2000
- Peripheral lymphocyte subsets and other immune aspects in Rett syndrome.
- Pediatr Neurol. 1999 Sep;21(3):619-21. Unique Identifier : AIDSLINE MED/99441845
- Fiumara A; Sciotto A; Barone R; D'Asero G; Munda S; Parano E; Pavone L; Department of Paediatric Neurology, Paediatric Clinic, University; of Catania, Italy.
- A possible role of the immune system in the pathogenesis of some neurologic disorders, including infantile autism, was recently postulated. This observation prompted the authors to investigate some immunologic aspects in a group of patients with Rett syndrome, a disorder still not completely clarified but with some po
- Synthesis and biological evaluation of [alpha-(1,5-disubstituted 1H-pyrazol-4-yl)benzyl]azoles, analogues of bifonazole.
- Unique Identifier : AIDSLINE MED/99371968
- Menozzi G; Mosti L; Bruno O; Lo Presti E; Musiu C; Longu S; La Colla P; Filippelli W; Falcone G; Piucci B; Dipartimento di Scienze Farmaceutiche, Universita di Genova,; Italy. menozzi@unige.it
- A series of pyrazole analogues of bifonazole, an antifungal drug used in clinical practice, 2a-h and 4a-h were synthesized and tested in vitro against Candida albicans, Cryptococcus neoformans and Aspergillus fumigatus, with no significant results. Imidazoles 2a-h were also tested in vivo for antiarrhythmic and antihy
- Synthesis and antimicrobial activity of Schiff and Mannich bases of isatin and its derivatives with pyrimidine.
- Farmaco. 1999 Sep 30;54(9):624-8. Unique Identifier : AIDSLINE MED/20022964
- Pandeya SN; Sriram D; Nath G; De Clercq E; Department of Pharmaceutics, Banaras Hindu University, Varanasi,; India. snpande@banaras.ernet.in
- Isatin and its derivatives have been reacted with 4-(4 -chlorophenyl)-6-(4 -methyl phenyl)-2-aminopyrimidine to form Schiff bases and the N-Mannich bases of these compounds were synthesized by reacting them with formaldehyde and several secondary amines. Investigation of antimicrobial activity of the compounds was mad
- Regression and spreading of self-recognition during the development of autoimmune demyelinating disease.
- J Autoimmun. 1999 Aug;13(1):11-20. Unique Identifier : AIDSLINE MED/99371720
- Tuohy VK; Yu M; Yin L; Kawczak JA; Kinkel PR; Department of Immunology, Lerner Research Institute, The; Cleveland Clinic Foundation, Cleveland, OH, 44195, USA.; tuohv@ccf.org
- The autoimmune T cell repertoire in experimental autoimmune encephalomyelitis (EAE) and multiple sclerosis (MS) is characterized by CD4(+)T cells of the Th1 phenotype that recognize peptide determinants of central nervous system (CNS) myelin proteins in an MHC class II-restricted manner. Our recent studies and those p
- Human retrovirus-5 in rheumatic disease.
- J Autoimmun. 1999 Aug;13(1):149-54. Unique Identifier : AIDSLINE MED/99371737
- Brand A; Griffiths DJ; Herve C; Mallon E; Venables PJ; Chelsea and Westminster Hospital, London, UK.
- It has long been suggested that retroviral infection may play a role in the pathogenesis of autoimmune rheumatic disease. Particles resembling retroviruses have been reported in tissue from patients with Sjogren s syndrome, lupus and rheumatoid arthritis, and molecular mimicry between retroviral antigens and host prot
- Th1 predominance and perforin expression in minor salivary glands from patients with primary Sjogren's syndrome.
- J Autoimmun. 1999 Aug;13(1):155-62. Unique Identifier : AIDSLINE MED/99371738
- Kolkowski EC; Reth P; Pelusa F; Bosch J; Pujol-Borrell R; Coll J; Jaraquemada D; Immunology Unit, Facultat de Medicina, Universitat Autonoma de; Barcelona, Barcelona, Spain.
- Objectives of this study were to examine the cytokine and perforin mRNA expression in minor salivary glands from patients with primary Sjogren s syndrome (pSS), searching for possible correlation with clinical parameters and to identify the dominant cytokine pattern in the different groups. Oral mucosa biopsy samples
- Th2 T cells expressing transgene PDGF-A serve as vectors for gene therapy in autoimmune demyelinating disease.
- J Autoimmun. 1999 Aug;13(1):31-8. Unique Identifier : AIDSLINE MED/99371722
- Mathisen PM; Yu M; Yin L; Johnson JM; Kawczak JA; Nishiyama A; Tuohy VK; Department of Immunology, Lerner Research Institute, The; Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH,; 44195, USA.
- We hypothesized that T cells can be genetically modified to express growth factor transgene products capable of inducing oligodendrocyte progenitor proliferation. Autoreactive T cells isolated from SWXJ mice immunized with the p139-151 determinant of myelin proteolipid protein (PLP) were transfected with an antigen-in
- Plasma lactoferrin levels are decreased in end-stage AIDS patients.
- Viral Immunol. 1999;12(3):197-203. Unique Identifier : AIDSLINE MED/20000448
- van der Strate BW; Harmsen MC; The TH; Sprenger HG; de Vries H; Eikelboom MC; Kuipers ME; Meijer DK; Swart PJ; Department of Pharmacokinetics and Drug Delivery, Groningen; University Institute for Drug Exploration, University Centre for; Pharmacy, The Netherlands. B.W.A.van.der.Strate@farm.rug.nl
- The antimicrobial protein lactoferrin (Lf) is present in plasma and in mucosal secretions. Using ELISA we analysed plasma and saliva of HIV-infected patients, patients with AIDS, and healthy controls for the presence of secreted Lf. The plasma Lf levels of AIDS patients (classification C3) were significantly lower (p
- Immunogenicity of full length and truncated SIV envelope proteins.
- Viral Immunol. 1999;12(3):205-15. Unique Identifier : AIDSLINE MED/20000449
- Vzorov AN; Lea-Fox D; Compans RW; Department of Microbiology and Immunology, Emory University; School of Medicine, Atlanta, Georgia 30322, USA.
- We have compared the immunogenicity of the full-length (FL) SIV envelope (Env) protein and a truncated (T) form of the Env protein which has a short cytoplasmic tail. The Env(T) protein was previously shown to be more fusogenic than Env(FL), has a higher level of incorporation into virus-like particles (VLPs) and memb
- Plasmid expressing the influenza HA gene protects old mice from lethal challenge with influenza virus.
- Viral Immunol. 1999;12(3):217-26. Unique Identifier : AIDSLINE MED/20000450
- Radu DL; Antohi S; Bot A; Weksler ME; Bona C; Department of Microbiology, Mount Sinai School of Medicine, New; York, New York 10029, USA.
- Virus-based influenza vaccines induce less protection in old compared to young subjects due, in part, to age-associated alterations in the immune response. This study shows that old mice produce a less diverse HI antibody response after immunization than adult mice. However, immunization of old and young mice with pla
- Accommodation.
- Immunol Today. 1999 Oct;20(10):434-7. Unique Identifier : AIDSLINE MED/99431571
- Soares MP; Lin Y; Sato K; Stuhlmeier KM; Bach FH; Immunobiology Research Center, Beth Israel Deaconess Medical; Center, Harvard Medical School, Boston, MA 02215, USA.; msoares@caregroup.harvard.edu
- Measurement of T-cell kinetics: recent methodologic advances.
- Immunol Today. 1999 Oct;20(10):438-41. Unique Identifier : AIDSLINE MED/99431572
- Hellerstein MK; Dept of Nutritional Sciences, 309 Morgan Hall, University of; California at Berkeley, CA 94720-3104, USA.; march@nature.berkeley.edu
- The moving target: mechanisms of HIV persistence during primary infection.
- Immunol Today. 1999 Oct;20(10):446-50. Unique Identifier : AIDSLINE MED/99431574
- Soudeyns H; Pantaleo G; Laboratory of AIDS Immunopathogenesis, Dept of Internal Medicine,; Centre Hospitalier Universitaire Vaudois, Lausanne 1011,; Switzerland.
- The vigorous host immune responses detected during primary HIV infection fail to prevent the establishment of chronic infection because HIV has evolved multiple strategies to make these responses ineffective. Here, Hugo Soudeyns and Giuseppe Pantaleo discuss the mechanisms that allow HIV to persist in the host.
- Positive selection of thymocytes: the long and winding road.
- Immunol Today. 1999 Oct;20(10):463-8. Unique Identifier : AIDSLINE MED/99431577
- Anderson G; Hare KJ; Jenkinson EJ; Dept of Anatomy, MRC Centre for Immune Regulation, Division of; Infection and Immunity, The Medical School, University of; Birmingham, Edgbaston, Birmingham, UK B15 2TT.; andersog@novell2.bham.ac.uk
- Positive selection is a crucial stage in T-cell development because it is here that CD4+CD8+ cells bearing T-cell receptors that interact with self-major histocompatibility complex molecules are rescued from cell death, resulting in the generation of mature T cells. Here, Graham Anderson and colleagues review recent s
- Is there a balance between microglia and astrocytes in regulating Th1/Th2-cell responses and neuropathologies?
- Immunol Today. 1999 Nov;20(11):477-9. Unique Identifier : AIDSLINE MED/20001982
- Xiao BG; Link H; Division of Neurology, Karolinska Institute, Huddinge University; Hospital, S-141 86 Huddinge, Stockholm, Sweden.; bao-guo.xiao@neurotec.ki.se
- Can eradication of helminthic infections change the face of AIDS and tuberculosis?
- Immunol Today. 1999 Nov;20(11):485-7. Unique Identifier : AIDSLINE MED/20001984
- Bentwich Z; Kalinkovich A; Weisman Z; Borkow G; Beyers N; Beyers AD; R. Ben-Ari Institute of Clinical Immunology, AIDS Center, Kaplan; Medical Center, Hebrew University Hadassah Medical School,; Rehovot, Israel. bentwich@agri.huji.ac.il
- Eotaxin: from an eosinophilic chemokine to a major regulator of allergic reactions.
- Immunol Today. 1999 Nov;20(11):500-4. Unique Identifier : AIDSLINE MED/20001987
- Gutierrez-Ramos JC; Lloyd C; Gonzalo JA; Millennium Pharmaceuticals, 75 Sidney Street, Cambridge, MA; 02139, USA. gutierrez@mpi.com
- Th2-deviation of fetus-specific T cells [letter]
- Immunol Today. 1999 Nov;20(11):534. Unique Identifier : AIDSLINE MED/20001993
- Ekerfelt C; Matthiesen L; Berg G; Ernerudh J
- Imaging features of Pneumocystis carinii pneumonia.
- Crit Rev Diagn Imaging. 1999 Aug;40(4):251-84. Unique Identifier : AIDSLINE MED/99444526
- Crans CA Jr; Boiselle PM; Department of Diagnostic Imaging, Temple University Hospital,; Philadelphia, PA.
- Despite a declining prevalence secondary to improved prophylaxis, Pneumocystis carinii remains an important pulmonary pathogen in the immunocompromised host. Because the radiologist is often the first to suggest the diagnosis of PCP, an awareness of the entire spectrum of imaging features associated with this organism
- Chemokines and the human immunodeficiency virus.
- Chem Immunol. 1999;72:121-40. Unique Identifier : AIDSLINE MED/20018597
- Poli G; AIDS Immunophathogenesis Unit, DiBiT, San Raffaele Scientific; Institute, Milano, Italy. poli.guido@hsr.it
- Inhibition of the expression and function of chemokine receptors on human CD4+ leukocytes by HIV-1 envelope protein gp120.
- Chem Immunol. 1999;72:141-60. Unique Identifier : AIDSLINE MED/20018598
- Su SB; Ueda H; Howard OM; Grimm MC; Gong W; Ruscetti FW; Oppenheim JJ; Wang JM; Laboratory of Molecular Immunoregulation, SAIC, Frederick,; National Cancer Institute, Md., USA.
- Strategies to interfere with the chemokine network in disease.
- Chem Immunol. 1999;72:181-201. Unique Identifier : AIDSLINE MED/20018600
- Wells TN; Proudfoot AE; Power CA; Serono Pharmaceutical Research Institute, Geneva, Switzerland.; Tim.wells@serono.com
- CCR2: from cloning to the creation of knockout mice.
- Chem Immunol. 1999;72:30-41. Unique Identifier : AIDSLINE MED/20018591
- Charo IF; Gladstone Institute of Cardiovascular Disease, San Francisco,; Calif., USA. icharo@gladstone.ucsf.edu
- The role of CD26/DPP IV in chemokine processing.
- Chem Immunol. 1999;72:42-56. Unique Identifier : AIDSLINE MED/20018592
- Van Damme J; Struyf S; Wuyts A; Van Coillie E; Menten P; Schols D; Sozzani S; De Meester I; Proost P; Laboratory of Molecular Immunology, University of Leuven,; Belgium. jozef.vandamme@rega.kuleuven.ac.be
- DNA priming-protein boosting enhances both antigen-specific antibody and Th1-type cellular immune responses in a murine herpes simplex virus-2 gD vaccine model.
- DNA Cell Biol. 1999 Oct;18(10):771-9. Unique Identifier : AIDSLINE MED/20007449
- Sin JI; Bagarazzi M; Pachuk C; Weiner DB; Department of Pathology and Laboratory Medicine, University of; Pennsylvania, Philadelphia 19104, USA.
- It has previously been reported that herpes simplex virus (HSV)-2 gD DNA vaccine preferentially induces T-helper (Th) 1-type cellular immune responses, whereas the literature supports the view that subunit vaccines tend to induce potent antibody responses, supporting a Th2 bias. Here, using an HSV gD vaccine model, we
- What is the role of regulatory T cells in transplantation tolerance?
- Curr Opin Immunol. 1999 Oct;11(5):497-503. Unique Identifier : AIDSLINE MED/99439585
- Zhai Y; Kupiec-Weglinski JW; The Dumont-UCLA Transplant Center, University of California (Los; Angeles) School of Medicine, Department of Surgery, Room 77-120,; Center for Health Science, 10833 Le Conte Avenue, Los Angeles, CA; 90095, USA.
- There has been considerable recent progress in the characterization of the regulatory T cells that mediate tolerance in a number of transplantation models. The conditions that facilitate the generation of regulatory T cells point to the thymus, the nature of immune suppression and the dose of immunosuppressive agent(s
- Hydroxyurea and HIV: 5 years later--from antiviral to immune-modulating effects [editorial]
- AIDS. 1999 Aug 20;13(12):1433-42. Unique Identifier : AIDSLINE MED/99392734
- Lori F
- A soluble factor produced by macrophages mediates the neurotoxic effects of HIV-1 Tat in vitro.
- AIDS. 1999 Aug 20;13(12):1443-52. Unique Identifier : AIDSLINE MED/99392735
- Brana C; Biggs TE; Barton CH; Sundstrom LE; Mann DA; Department of Clinical Neurological Sciences, University of; Southampton, Southampton General Hospital, UK.
- OBJECTIVES: There is now a strong consensus that the neurotoxic properties of HIV-1 are likely to be mediated by an indirect mechanism in which neurones are damaged by infected mononuclear cells. The aim of this study was to determine the ability of HIV-1 Tat to induce neurotoxic properties in a murine macrophage cell
- The CDK9-associated cyclins T1 and T2 exert opposite effects on HIV-1 Tat activity.
- AIDS. 1999 Aug 20;13(12):1453-9. Unique Identifier : AIDSLINE MED/99392736
- Napolitano G; Licciardo P; Gallo P; Majello B; Giordano A; Lania L; Department of Genetics, University of Naples Federico II, and; International Institute of Genetics and Biophysics, Italy.
- OBJECTIVES: To examine the functional interaction between HIV-1 Tat protein and the cyclin T1 and T2 proteins which, in association with cyclin dependent kinase (CDK)9, are the regulatory subunits of the TAK/P-TEFb cellular complex strictly required for Tat transactivation. DESIGN: HIV-1 long terminal repeat (LTR) rep
- Recombinant gp160 as a therapeutic vaccine for HIV-infection: results of a large randomized, controlled trial. European Multinational IMMUNO AIDS Vaccine Study Group.
- AIDS. 1999 Aug 20;13(12):1461-8. Unique Identifier : AIDSLINE MED/99392737
- Goebel FD; Mannhalter JW; Belshe RB; Eibl MM; Grob PJ; de Gruttola V; Griffiths PD; Erfle V; Kunschak M; Engl W; Medizinische Poliklinik, University of Munich, Germany.
- OBJECTIVES: The primary objective of this study was to expand the safety and immunogenicity database of recombinant gp160 as a therapeutic vaccine in the treatment of HIV-infection. Preliminary efficacy data was also sought. DESIGN: This trial was a randomized, double-blind, placebo-controlled study. Two-hundred and e
- Human polyomavirus JC latency and reactivation status in blood of HIV-1-positive immunocompromised patients with and without progressive multifocal leukoencephalopathy.
- AIDS. 1999 Aug 20;13(12):1469-75. Unique Identifier : AIDSLINE MED/99392738
- Andreoletti L; Dubois V; Lescieux A; Dewilde A; Bocket L; Fleury HJ; Wattre P; Laboratoire de Virologie, Lille, France.
- BACKGROUND: Human polyomavirus JC (JCV) induces human progressive multifocal leukoencephalopathy (PML) in patients with AIDS. Peripheral blood mononuclear cells (PBMC) of HIV-1-positive immunocompetent and immunocompromised patients can harbour JCV genome, but their precise role in JCV latency or reactivation status b
- Activity of non-nucleoside reverse transcriptase inhibitors against HIV-2 and SIV.
- AIDS. 1999 Aug 20;13(12):1477-83. Unique Identifier : AIDSLINE MED/99392739
- Witvrouw M; Pannecouque C; Van Laethem K; Desmyter J; De Clercq E; Vandamme AM; Rega Institute for Medical Research, Leuven, Belgium.
- BACKGROUND: After the initial discovery of 1-(2-hydroxyethoxymethyl)-6-(phenylthio)thymine (HEPT) and tetrahydroimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-one and thione (TIBO) derivatives, several other non-nucleoside reverse transcriptase (RT) inhibitors (NNRTI), including
- Salvage therapy with regimens containing ritonavir and saquinavir in extensively pretreated HIV-infected patients.
- AIDS. 1999 Aug 20;13(12):1485-9. Unique Identifier : AIDSLINE MED/99392740
- Fatkenheuer G; Hoetelmans RM; Hunn N; Schwenk A; Franzen C; Reiser M; Jutte A; Rockstroh J; Diehl V; Salzberger B; Department of Internal Medicine, University of Koln, Germany.
- OBJECTIVE: To evaluate the efficacy and toxicity of salvage regimens containing ritonavir and saquinavir in patients failing highly active antiretroviral therapy (HAART), and to correlate outcome with plasma concentrations of
- Cerebrospinal fluid HIV-1 RNA levels in asymptomatic patients with early stage chronic HIV-1 infection: support for the hypothesis of local virus replication.
- AIDS. 1999 Aug 20;13(12):1491-6. Unique Identifier : AIDSLINE MED/99392741
- Garcia F; Niebla G; Romeu J; Vidal C; Plana M; Ortega M; Ruiz L; Gallart T; Clotet B; Miro JM; Pumarola T; Gatell JM; Infectious Diseases Unit, Institut d'Investigacions Biomediques,; August Pi I Sunyer Hospital Clinic, Faculty of Medicine,; University of Barcelona, Spain.
- OBJECTIVE: To assess HIV-1 RNA levels in cerebrospinal fluid (CSF) and their potential correlation with plasma viral load and central nervous system (CNS) HIV-1 infection markers in stable asymptomatic patients with a CD4 T cell count >500x10(6) cells/l. PATIENTS AND METHODS: Consecutive patients screened for two tria
- Incidence and risk factors for developing cytomegalovirus retinitis in HIV-infected patients receiving protease inhibitor therapy. Spanish CMV-AIDS Study Group.
- AIDS. 1999 Aug 20;13(12):1497-502. Unique Identifier : AIDSLINE MED/99392742
- Casado JL; Arrizabalaga J; Montes M; Marti-Belda P; Tural C; Pinilla J; Gutierrez C; Portu J; Schuurman R; Aguirrebengoa K; Infectious Diseases Unit, Hospital Ramon y Cajal, Madrid, Spain.
- OBJECTIVE: To assess the incidence and risk factors for cytomegalovirus ( CMV ) retinitis in HIV-infected patients who initiated protease inhibitor-containing antiretroviral therapy. DESIGN AND SETTING: Prospective, multicentre
- Sampling lymphoid tissue cells by ultrasound-guided fine needle aspiration of lymph nodes in HIV-infected patients. Swiss HIV Cohort Study.
- AIDS. 1999 Aug 20;13(12):1503-9. Unique Identifier : AIDSLINE MED/99392743
- Bart PA; Meuwly JY; Corpataux JM; Yerly S; Rizzardi P; Fleury S; Munoz M; Knabenhans C; Welbon C; Pantaleo G; Meylan PR; Division of Infectious Diseases, Centre Hospitalier Universitaire; Vaudois, University of Lausanne, Switzerland.
- OBJECTIVE: To establish the feasibility of using ultrasound-guided lymph node needle aspiration as a means to obtain lymphoid tissue cells for the determination of a series of immunologic and virologic measures in HIV-infected patients. DESIGN: First, a comparison of the characteristics of cell populations obtained by
- Phase 1 trial of nonoxynol-9 film among sex workers in South Africa.
- AIDS. 1999 Aug 20;13(12):1511-5. Unique Identifier : AIDSLINE MED/99392744
- Rustomjee R; Abdool Karim Q; Abdool Karim SS; Laga M; Stein Z; Centre for Epidemiological Research in South Africa, South; African Medical Research Council, Durban.
- OBJECTIVES: To assess the acceptability and safety of a vaginal nonoxynol-9 film in a group of sex workers at a truck stop in South Africa . DESIGN: A randomized double-blinded crossover trial was conducted between April 1995 and July 1995. INTERVENTION: Seventy-two mg nonoxynol-9
- Randomized trial testing the effect of vitamin A supplementation on pregnancy outcomes and early mother-to-child HIV-1 transmission in Durban, South Africa. South African Vitamin A Study Group.
- AIDS. 1999 Aug 20;13(12):1517-24. Unique Identifier : AIDSLINE MED/99392745
- Coutsoudis A; Pillay K; Spooner E; Kuhn L; Coovadia HM; Department of Paediatrics and Child Health, University of Natal,; Africa Centre for Population Studies and Reproductive Health,; South Africa.
- OBJECTIVE: Poor vitamin A status has been associated with a higher risk for mother-to-child transmission of HIV-1 and there is contradictory evidence on the impact of vitamin A on perinatal outcome. We therefore assessed the effect of vitamin A supplementation to mothers on birth outcome and mother-to-child transmissi
- Gay men report high rates of unprotected anal sex with partners of unknown or discordant HIV status.
- AIDS. 1999 Aug 20;13(12):1525-33. Unique Identifier : AIDSLINE MED/99392746
- Ekstrand ML; Stall RD; Paul JP; Osmond DH; Coates TJ; Center for AIDS Prevention Studies, University of California, San; Francisco, USA.
- OBJECTIVE: To examine patterns and factors that correlate with unprotected anal intercourse (UAI) practices among San Francisco gay men, including UAI with partners of unknown or different HIV antibody status. DESIGN: A longitudinal cohort recruited for the San Francisco Young Men s Health Study in 1992; re-assessed a
- Mortality in young adults in England and Wales: the impact of the HIV epidemic.
- AIDS. 1999 Aug 20;13(12):1535-41. Unique Identifier : AIDSLINE MED/99392747
- Nylen G; Mortimer J; Evans B; Gill N; PHLS AIDS and STD Centre, Communicable Diseases Surveillance; Centre, London, UK.
- OBJECTIVE: To quantify the contribution of the HIV epidemic to premature mortality in England and Wales 1985-1996. DESIGN: Surveillance of deaths in HIV-infected individuals and causes of death from death certificates. MAIN OUTCOME MEASURES: Time trends in age-specific mortality rates among 15-44 year olds and years o
- Relapse and mortality among HIV-infected and uninfected patients with tuberculosis successfully treated with twice weekly directly observed therapy in rural South Africa.
- AIDS. 1999 Aug 20;13(12):1543-7. Unique Identifier : AIDSLINE MED/99392748
- Connolly C; Reid A; Davies G; Sturm W; McAdam KP; Wilkinson D; Centre for Epidemiological Research in South Africa, Medical; Research Council, Durban.
- OBJECTIVE: To determine post-treatment relapse and mortality rates among HIV-infected and uninfected patients with tuberculosis treated with a twice-weekly drug regimen under direct observation (DOT). SETTING: Hlabisa, South Africa . PATIENTS: A group of 403 patients with tuberculo
- Tuberculosis preventive therapy for HIV-infected people in sub-Saharan Africa is cost-effective [see comments]
- AIDS. 1999 Aug 20;13(12):1549-56. Unique Identifier : AIDSLINE MED/99392749
- Bell JC; Rose DN; Sacks HS; Thomas C. Chalmers Clinical Trials Unit, Mount Sinai School of; Medicine, New York, New York 10029, USA.
- OBJECTIVE: Since antiretroviral therapy is largely unavailable to HIV-infected patients in developing countries and recent clinical trials have shown that tuberculosis (TB) preventive therapy can reduce TB and HIV-associated morbidity and mortality, we studied the effectiveness and cost-effectiveness of TB preventive
- A psychological epidemiology of people seeking HIV/AIDS counselling in Kenya: an approach for improving counsellor training [see comments]
- AIDS. 1999 Aug 20;13(12):1557-67. Unique Identifier : AIDSLINE MED/99392750
- Vollmer NA; Valadez JJ; Plan International, Arlington, VA 22201, USA.
- OBJECTIVE: This study develops a typology of psychological problems reported during HIV/AIDS counselling. This typology provides a framework for training paraprofessional counsellors (PPCs) in East Africa. DESIGN: Study participants included 307 Kenyans tested for HIV at any of six clinics in Nairobi specialising in S
- Costs and benefits to the mother of antenatal HIV testing: estimates from simulation modelling.
- AIDS. 1999 Aug 20;13(12):1569-76. Unique Identifier : AIDSLINE MED/99392751
- Gibb DM; Ades AE; Gupta R; Sculpher MJ; MRC Clinical Trials Unit, University College London Medical; School, UK.
- OBJECTIVE: To assess the health service costs and benefits for the woman of an earlier HIV diagnosis as a result of antenatal HIV testing. DESIGN: A model of maternal disease progression was developed based on the rate of decline in CD4 cell counts and applied to two matched simulated cohorts of women with identical i
- HIV counseling in sub-Saharan Africa [editorial; comment]
- AIDS. 1999 Aug 20;13(12):1577-9. Unique Identifier : AIDSLINE MED/99392752
- Kaaya SF; Fawzi MC
- Tuberculosis preventive therapy in people living with HIV in sub-Saharan Africa [editorial; comment]
- AIDS. 1999 Aug 20;13(12):1581-2. Unique Identifier : AIDSLINE MED/99392753
- Godfrey-Faussett P
- HLA-unrestricted killing of HIV-1 gag protein-expressing CD4 T cells by gag-specific CD8 cytotoxic T cells [letter; comment]
- AIDS. 1999 Aug 20;13(12):1583-4. Unique Identifier : AIDSLINE MED/99392754
- Salerno-Goncalves R; Lu W; Achour A; Andrieu JM
- Characterization of a third CCR5 amplicon from CCR5-delta32-heterozygous HIV-1-infected individuals [letter]
- AIDS. 1999 Aug 20;13(12):1585-6. Unique Identifier : AIDSLINE MED/99392755
- Aikhionbare FO; Newman C; Womack C; Roth WW; Stringer HG Jr; Bond VC
- Reversible zidovudine-induced pure red cell aplasia [letter]
- AIDS. 1999 Aug 20;13(12):1586-7. Unique Identifier : AIDSLINE MED/99392756
- Blanche P; Silberman B; Barreto L; Gombert B; Sicard D
- Quality of life in asymptomatic patients with early HIV infection initiating antiretroviral therapy. Swiss HIV Cohort Study [letter]
- AIDS. 1999 Aug 20;13(12):1587-9. Unique Identifier : AIDSLINE MED/99392757
- Zinkernagel C; Ledergerber B; Battegay M; Cone RW; Vernazza P; Hirschel B; Opravil M
- Treatment of painful distal sensory polyneuropathy in HIV-infected patients with a topical agent: results of an open-label trial of 5% lidocaine gel [letter]
- AIDS. 1999 Aug 20;13(12):1589-90. Unique Identifier : AIDSLINE MED/99392758
- Dorfman D; Dalton A; Khan A; Markarian Y; Scarano A; Cansino M; Wulff E; Simpson D
- Serum thrombopoietin levels correlate with disease progression of AIDS [letter]
- AIDS. 1999 Aug 20;13(12):1590-1. Unique Identifier : AIDSLINE MED/99392759
- Gatanaga H; Hoshikawa N; Tahara T; Kato T; Oka S
- Salvage therapy in HIV-positive patients with a previous therapeutic experience with protease inhibitors. Members of the Master Group [letter]
- AIDS. 1999 Aug 20;13(12):1591-2. Unique Identifier : AIDSLINE MED/99392760
- Maggiolo F; Maserati R; Pan A; Castelli F; Suter F
- Hydroxyurea-induced neurotoxicity in HIV disease [letter]
- AIDS. 1999 Aug 20;13(12):1592-4. Unique Identifier : AIDSLINE MED/99392761
- Barry M; Clarke S; Mulcahy F; Back D
- Changes in plasma HIV-RNA and CD4 lymphocyte counts in patients receiving highly active antiretroviral therapy [letter]
- AIDS. 1999 Aug 20;13(12):1594-5. Unique Identifier : AIDSLINE MED/99392762
- Maggiolo F; Bottura P; Capra R; Pirali A; Zaffaroni P; Suter F
- The frequency of anonymous HIV testing in the United States: data from a national survey [letter]
- AIDS. 1999 Aug 20;13(12):1595-7. Unique Identifier : AIDSLINE MED/99392763
- Anderson JE
- Sentinel surveillance for HIV infection and risk behavior among adolescents entering juvenile detention in San Francisco: 1990-1995 [letter]
- AIDS. 1999 Aug 20;13(12):1597-8. Unique Identifier : AIDSLINE MED/99392764
- Kim AA; McFarland W; Kellogg T; Katz MH
- Adjustment of antenatal clinic HIV surveillance data for HIV-associated differences in fertility [letter; comment]
- AIDS. 1999 Aug 20;13(12):1598-9. Unique Identifier : AIDSLINE MED/99392765
- Glynn JR; Buve A; Carael M; Zaba B
- Sexual behavioural study of commercial sex workers and their clients in Cambodia. Japan-Cambodia Collaborating Research Group [letter]
- AIDS. 1999 Aug 20;13(12):1599-601. Unique Identifier : AIDSLINE MED/99392766
- Morio S; Soda K; Tajima K; Leng HB
- Changes in viral load during acute respiratory infections in HIV-infected patients [letter]
- AIDS. 1999 Aug 20;13(12):1601-2. Unique Identifier : AIDSLINE MED/99392767
- Villar-Arias A; Pinilla-Moraza J; Labarga-Echeverria P; Anton-Botella F
- The interaction of opportunistic infections and HIV replication [editorial]
- AIDS. 1999 Sep 10;13(13):1603-6. Unique Identifier : AIDSLINE MED/99437258
- Powderly WG
- Cell-associated HIV-1 messenger RNA and DNA in T-helper cell and monocytes in asymptomatic HIV-1-infected subjects on HAART plus an inactivated HIV-1 immunogen.
- AIDS. 1999 Sep 10;13(13):1607-11. Unique Identifier : AIDSLINE MED/99437259
- Patterson BK; Carlo DJ; Kaplan MH; Marecki M; Pawha S; Moss RB; Northwestern University Medical School, Department of; Obstetrics/Gynecology and Medicine, Chicago, Illinois 60611, USA.; bpatters@nmh.org
- OBJECTIVE: We examined the effect of an HIV-1-specific immune-based therapy on cell-associated HIV-1 DNA and RNA. DESIGN: Five HIV-1-infected subjects receiving HIV-1 immunogen plus HAART were compared with three HIV-1-infected subjects who received incomplete Freund s adjuvant (IFA) plus HAART. METHODS: Cell-associat
- Emerging recombinant human immunodeficiency viruses: uneven representation of the envelope V3 region.
- AIDS. 1999 Sep 10;13(13):1613-21. Unique Identifier : AIDSLINE MED/99437260
- Renjifo B; Gilbert P; Chaplin B; Vannberg F; Mwakagile D; Msamanga G; Hunter D; Fawzi W; Essex M; Harvard AIDS Institute, Boston, Massachusetts 02115-6017, USA.
- OBJECTIVE: To determine whether the envelope V3 region from HIV-1 subtypes A, C or D had the same probability of being present in intersubtype recombinant genomes. MATERIALS AND METHODS: The envelope C2-C5 and the gag p24-p7 regions from one hundred infants infected perinatally in Ta
- Modulation of P-glycoprotein function in human lymphocytes and Caco-2 cell monolayers by HIV-1 protease inhibitors.
- AIDS. 1999 Sep 10;13(13):1623-7. Unique Identifier : AIDSLINE MED/99437261
- Profit L; Eagling VA; Back DJ; Department of Pharmacology and Therapeutics, University of; Liverpool, UK.
- OBJECTIVES: To determine the effect of the protease inhibitors ritonavir , nelfinavir and indinavir on the P-glycoprotein (P-gp)-me
- Peripheral blood mononuclear cell markers in antiretroviral therapy-naive HIV-infected and high risk seronegative adolescents. Adolescent Medicine HIV/AIDS Research Network.
- AIDS. 1999 Sep 10;13(13):1629-35. Unique Identifier : AIDSLINE MED/99437262
- Douglas SD; Rudy B; Muenz L; Moscicki AB; Wilson CM; Holland C; Crowley-Nowick P; Vermund SH; Children's Hospital of Philadelphia, Department of Pediatrics of; the University of Pennsylvania School of Medicine, 19104-4399,; USA.
- OBJECTIVE: To examine potential hematologic and immunologic markers for healthy adolescents and for adolescents infected with HIV. DESIGN: The REACH Project (Reaching for Excellence in Adolescent Care and Health) of the Adolescent Medicine HIV/AIDS Research Network (AMHARN) recruits HIV-infected and high-risk HIV-unin
- Extracellular HIV-1 Tat protein differentially activates the JNK and ERK/MAPK pathways in CD4 T cells.
- AIDS. 1999 Sep 10;13(13):1637-45. Unique Identifier : AIDSLINE MED/99437263
- Mischiati C; Pironi F; Milani D; Giacca M; Mirandola P; Capitani S; Zauli G; Department of Morphology and Embryology, University of Ferrara,; Italy.
- OBJECTIVE: To investigate the intracellular signals elicited by extracellular HIV-1 Tat protein in lymphoid CD4 T cells. METHODS: CD4 Jurkat T cells were treated with a series of glutathione S-transferase (GST)-Tat fusion proteins: full-length two-exon GST-Tat (GST-Tat2E); one-exon Tat, in which the second exon of Tat
- Can chemoprophylaxis against opportunistic infections be discontinued after an increase in CD4 cells induced by highly active antiretroviral therapy?
- AIDS. 1999 Sep 10;13(13):1647-51. Unique Identifier : AIDSLINE MED/99437264
- Kirk O; Lundgren JD; Pedersen C; Nielsen H; Gerstoft J; Department of Infectious Diseases, Hvidovre Hospital, University; of Copenhagen, Hvidovre, Denmark.
- BACKGROUND: In the USPHS/IDSA Guidelines for Prevention of Opportunistic Infections in Persons Infected with Human Immunodeficiency Virus , the indications for chemoprophylaxis are based on nadir CD4 cell count. Many patients have, however, experienced an increase in CD4 cell count after the introduction of highly ac
- Preliminary experiences with triple therapy including nelfinavir and two reverse transcriptase inhibitors in previously untreated HIV-infected children.
- AIDS. 1999 Sep 10;13(13):1653-8. Unique Identifier : AIDSLINE MED/99437265
- Funk MB; Linde R; Wintergerst U; Notheis G; Hoffmann F; Schuster T; Kornhuber B; Ahrens P; Kreuz W; Children's Hospital, Johann Wolfgang Goethe-University Frankfurt,; Germany.
- OBJECTIVE: In an intent-to-treat study increase in CD4 cell count, reduction of viral load, clinical benefit and adverse reactions were examined in HIV-infected previously treatment-naive children taking triple therapy. METHODS: sixteen HIV-infected children in category A or B on antiretroviral triple therapy were fol
- A syndrome of peripheral fat wasting (lipodystrophy) in patients receiving long-term nucleoside analogue therapy.
- AIDS. 1999 Sep 10;13(13):1659-67. Unique Identifier : AIDSLINE MED/99437266
- Saint-Marc T; Partisani M; Poizot-Martin I; Bruno F; Rouviere O; Lang JM; Gastaut JA; Touraine JL; Transplantation and Clinical Immunology Unit, Pavillon P,; Hopital Edouard-Herriot, Lyon, France.
- OBJECTIVE: To compare body composition, body fat distribution and insulin secretion in patients taking nucleoside reverse transcriptase inhibitor (NRTI) therapy. DESIGN AND SETTING: Cross-sectional study in three French AIDS clinical centres. PATIENTS: Forty-three HIV-infected patients on long-term NRTI therapy includ
- CD4 cell counts at the third month of HAART may predict clinical failure.
- AIDS. 1999 Sep 10;13(13):1669-76. Unique Identifier : AIDSLINE MED/99437267
- d'Arminio Monforte A; Testori V; Adorni F; Castelnuovo B; Bini T; Testa L; Moscatelli G; Chiesa E; Rusconi S; Abeli C; Sollima S; Musicco M; Meroni L; Galli M; Moroni M; Institute of Infectious and Tropical Diseases, University of; Milan, Italy.
- OBJECTIVE: To evaluate the influence of immunological and virological markers on clinical outcome in patients receiving their first highly active antiretroviral therapy (HAART) regimen. DESIGN AND METHODS: Observational study of 585 patients initiating HAART in a clinical setting. Clinical failure was defined as the o
- Neurological outcomes in late HIV infection: adverse impact of neurological impairment on survival and protective effect of antiviral therapy. AIDS Clinical Trial Group and Neurological AIDS Research Consortium study team.
- AIDS. 1999 Sep 10;13(13):1677-85. Unique Identifier : AIDSLINE MED/99437268
- Price RW; Yiannoutsos CT; Clifford DB; Zaborski L; Tselis A; Sidtis JJ; Cohen B; Hall CD; Erice A; Henry K; University of California, San Francisco, USA.
- OBJECTIVE: In a large multi-center clinical trial of combination reverse transcriptase inhibitors (RTIs), we assessed the impact of antiretroviral therapy on neurological function, the relationship between neurological and systemic benefit, and the prognostic value of neurological performance in late HIV-1 infection.
- Effects of antiretroviral therapy and opportunistic illness primary chemoprophylaxis on survival after AIDS diagnosis. Adult/Adolescent Spectrum of Disease Group.
- Unique Identifier : AIDSLINE MED/99437269
- McNaghten AD; Hanson DL; Jones JL; Dworkin MS; Ward JW; Council of State and Territorial Epidemiologists, Centers for; Disease Control and Prevention, Atlanta, Georgia 30333, USA.
- OBJECTIVE: To examine the effects of antiretroviral therapy (ART) and opportunistic illness chemoprophylaxis on the survival of persons with AIDS and survival time based on year of AIDS diagnosis. DESIGN: Longitudinal medical record review. SETTING: Ninety-three hospitals and clinics in nine cities in the USA. PATIENT
- Photofrin photodynamic therapy for treatment of AIDS-related cutaneous Kaposi's sarcoma.
- AIDS. 1999 Sep 10;13(13):1697-704. Unique Identifier : AIDSLINE MED/99437270
- Bernstein ZP; Wilson BD; Oseroff AR; Jones CM; Dozier SE; Brooks JS; Cheney R; Foulke L; Mang TS; Bellnier DA; Dougherty TJ; Department of Medicine, Roswell Park Cancer Institute, Buffalo,; New York 14263, USA.
- OBJECTIVE: Kaposi s sarcoma, the most common malignancy in AIDS patients, often presents with painful cutaneous lesions that are difficult to treat effectively despite a wide variety of therapeutic approaches. We used photodynamic therapy in an attempt to provide effective palliative treatment for this disease. METHOD
- Emergence of zidovudine and multidrug-resistance mutations in the HIV-1 reverse transcriptase gene in therapy-naive patients receiving stavudine plus didanosine combination therapy. STADI Group.
- AIDS. 1999 Sep 10;13(13):1705-9. Unique Identifier : AIDSLINE MED/99437271
- Pellegrin I; Izopet J; Reynes J; Denayrolles M; Montes B; Pellegrin JL; Massip P; Puel J; Fleury H; Segondy M; Department of Virology, Bordeaux University Hospital, France.
- OBJECTIVE: Assessment of genotypic changes in the reverse transcriptase gene of HIV-1 occurring in antiretroviral naive patients treated by stavudine plus didanosine combination therapy . METHODS: Sequence analysis (codons 1-230) was performed after amplification of the
- Methadone maintenance treatment modalities in relation to incidence of HIV: results of the Amsterdam cohort study.
- AIDS. 1999 Sep 10;13(13):1711-6. Unique Identifier : AIDSLINE MED/99437272
- Langendam MW; van Brussel GH; Coutinho RA; van Ameijden EJ; Division of Public Health and Environment, Municipal Health; Service, Amsterdam, The Netherlands. mlangendam@gggd.amsterdam.nl
- STUDY OBJECTIVE: To evaluate methadone maintenance treatment modalities, prescribed within the concept of harm reduction, in relation to incidence of HIV infection among drug users with a history of methadone treatment in Amsterdam, The Netherlands . DESIGN: Prospective observa
- The relative value of CD4 cell count and quantitative HIV-1 RNA in predicting survival in HIV-1-infected women: results of the women's interagency HIV study.
- AIDS. 1999 Sep 10;13(13):1717-26. Unique Identifier : AIDSLINE MED/99437273
- Anastos K; Kalish LA; Hessol N; Weiser B; Melnick S; Burns D; Delapenha R; DeHovitz J; Cohen M; Meyer W; Bremer J; Kovacs A; Montefiore Medical Center, Bronx, New York, USA.
- OBJECTIVES: To determine factors associated with survival and to assess the relative strength of CD4 cell count and HIV-1 RNA in predicting survival in a cohort of HIV-1-infected women. DESIGN: Prospective cohort, enrolled during 1994-1995, with median follow-up of 29 months RESULTS: Of 1769 HIV-infected women 252 die
- A randomized study comparing instruments for measuring health-related quality of life in HIV-infected patients. Spanish MOS-HIV and MQOL-HIV Validation Group. Medical Outcomes Study HIV Health Survey.
- Unique Identifier : AIDSLINE MED/99437274
- Badia X; Podzamczer D; Garcia M; Lopez-Lavid C C; Consiglio E; Catalan Institute of Public Health, University of Barcelona,; L'Hospitalet de Llobregat, Spain. xbadia@bell.ub.es
- OBJECTIVE: To compare the feasibility, reliability, validity and sensitivity to change of the MOS-HIV and MQOL-HIV in order to determine their suitability for use in clinical research. METHODS: Five hundred and fifty-eight HIV-infected patients and 80 healthy blood donors were randomly assigned to receive the MOS-HIV
- Nosocomial HIV-transmission in an outpatient clinic detected by epidemiological and phylogenetic analyses [see comments]
- AIDS. 1999 Sep 10;13(13):1737-44. Unique Identifier : AIDSLINE MED/99437275
- Katzenstein TL; Jorgensen LB; Permin H; Hansen J; Nielsen C; Machuca R; Gerstoft J; Department of Infectious Diseases, Rigshopitalet, Copenhagen,; Denmark. Terese@RH.DK
- OBJECTIVE: To determine if a case of HIV-infection in a patient (GP) with common variable immunodeficiency, and with no known risk factors for HIV-infection, could be due to horizontal nosocomial transmission. METHODS: For determination of time of transmission stored serum-samples from GP were analysed for HIV RNA con
- Cost-effectiveness of counseling and testing and partner notification: a decision analysis.
- AIDS. 1999 Sep 10;13(13):1745-51. Unique Identifier : AIDSLINE MED/99437276
- Varghese B; Peterman TA; Holtgrave DR; Division of HIV/AIDS Prevention, Centers for Disease Control and; Prevention, Atlanta, Georgia 30333, USA.
- OBJECTIVE: Counseling and testing and partner notification are effective HIV prevention strategies, but they can be resource intensive. This paper evaluates the cost-effectiveness of partner notification and counseling and testing offered in HIV and sexually transmitted disease (STD) clinics in preventing future HIV i
- Mobilizing young gay and bisexual men for HIV prevention: a two-community study.
- AIDS. 1999 Sep 10;13(13):1753-62. Unique Identifier : AIDSLINE MED/99437277
- Kegeles SM; Hays RB; Pollack LM; Coates TJ; Center for AIDS Prevention Studies, University of California, San; Francisco 94105, USA.
- BACKGROUND: To develop, implement and evaluate a community-level HIV prevention program (the Mpowerment Project) for young gay men in two US communities. DESIGN: Using a multiple baseline design, a cohort of young gay men was recruited independently of the intervention in each community and surveyed twice (1 year apar
- Sociodemographic and psychological variables influencing adherence to antiretroviral therapy.
- AIDS. 1999 Sep 10;13(13):1763-9. Unique Identifier : AIDSLINE MED/99437278
- Gordillo V; del Amo J; Soriano V; Gonzalez-Lahoz J; Department of Research Methodology in Education, University; Complutense, Hospital Carlos III, Madrid, Spain.; gordillo@eucmax.sim.ucm.es
- OBJECTIVE: To assess the degree of compliance with antiretroviral therapy in HIV-infected patients, and identify which sociodemographic and psychological factors influence it, in order to develop strategies to improve adherence. DESIGN AND SETTING: Cross-sectional study in a reference HIV/AIDS institution located in M
- Adherence communication: a qualitative analysis of physician-patient dialogue.
- AIDS. 1999 Sep 10;13(13):1771-8. Unique Identifier : AIDSLINE MED/99437279
- Roberts KJ; Volberding P; Department of Sociology, University of California, Los Angeles; 90095-1551, USA.
- OBJECTIVE: To explore how HIV/AIDS care physicians communicate with HIV-positive patients about the need for adherence to antiretroviral treatment regimens. DESIGN: Semi-structured, face-to-face interviews, a qualitative research method. SETTING: A comprehensive, multidisciplinary, HIV/AIDS practice at San Francisco G
- Away with multi-use vials! [editorial; comment]
- AIDS. 1999 Sep 10;13(13):1779-81. Unique Identifier : AIDSLINE MED/99437280
- Mortimer PP
- HIV infection among pregnant women in the South African private medical sector [letter]
- AIDS. 1999 Sep 10;13(13):1783. Unique Identifier : AIDSLINE MED/99437281
- Wilkinson D
- Reliability of tuberculin purified derivative skin testing and delayed-type hypersensitivity skin test anergy in HIV-infected homosexual men, at risk of tuberculosis [letter]
- AIDS. 1999 Sep 10;13(13):1784-5. Unique Identifier : AIDSLINE MED/99437282
- Maas JJ; Foudraine NA; Schellekens PT; Mensen ME; Veenstra J; Roos MT; van Leeuwen R; Coutinho RA
- Mucus impaction presenting as a lung mass in an AIDS patient with asthma [letter]
- AIDS. 1999 Sep 10;13(13):1785-7. Unique Identifier : AIDSLINE MED/99437283
- Mc Ilraith TB; Noskin GA; Corbridge TC
- Hypersensitivity reactions to high-dose co-trimoxazole in HIV-infected Malaysian and Scottish patients [letter]
- AIDS. 1999 Sep 10;13(13):1787-8. Unique Identifier : AIDSLINE MED/99437284
- Pakianathan MR; Kamarulzaman A; Ismail R; McMillan A; Scott GR
- Ritonavir and warfarin interaction [letter]
- AIDS. 1999 Sep 10;13(13):1788-9. Unique Identifier : AIDSLINE MED/99437285
- Newshan G; Tsang P
- Impact of opportunistic diseases on survival in HIV-infected patients in France, 1992-1997. Clinical Epidemiology Group from Centres d'Information et de Soins de l'Immunodeficience Humaine [letter]
- AIDS. 1999 Sep 10;13(13):1789-90. Unique Identifier : AIDSLINE MED/99437286
- Lievre L; Meyohas MC; Costagliola D
- Exacerbation of skin mycobacterial lesions under highly active antiretroviral therapy in an HIV-infected patient [letter]
- AIDS. 1999 Sep 10;13(13):1790-1. Unique Identifier : AIDSLINE MED/99437287
- Sotto A; Guillot B; Dandurand M; Jourdan J
- A syndrome resembling primary aldosteronism (Conn syndrome) in untreated HIV disease [letter]
- AIDS. 1999 Sep 10;13(13):1791-2. Unique Identifier : AIDSLINE MED/99437288
- Stricker RB; Goldberg DA; Hu C; Hsu JW; Goldberg B
- Recurrence of cytomegalovirus retinitis in an HIV-infected patient responsive to highly active antiretroviral therapy late after discontinuation of gancyclovir [letter]
- AIDS. 1999 Sep 10;13(13):1792-4. Unique Identifier : AIDSLINE MED/99437289
- Bertelli D; Stellini R; Cadeo GP
- Ritonavir-saquinavir rescue therapy in HIV-positive patients failing with indinavir, rotinavir or saquinavir [letter]
- AIDS. 1999 Sep 10;13(13):1794-5. Unique Identifier : AIDSLINE MED/99437290
- De Wit S; Cassano P; Hermans P; Sommereijns B; Kabeya K; O'Doherty E; Clumeck N
- Increasing morbidity from myocardial infarction during HIV protease inhibitor treatment? [letter]
- AIDS. 1999 Sep 10;13(13):1796-7. Unique Identifier : AIDSLINE MED/99437291
- Jutte A; Schwenk A; Franzen C; Romer K; Diet F; Diehl V; Fatkenheuer G; Salzberger B
- Multiple myeloma in two HIV-infected patients [letter]
- AIDS. 1999 Sep 10;13(13):1797-9. Unique Identifier : AIDSLINE MED/99437292
- Faure I; Viallard JF; Mercie P; Bonnefoy M; Pellegrin JL; Leng B
- The gp120 envelope of HIV-1 binds and presents peptides in a similar manner to human leukocyte antigen [letter]
- AIDS. 1999 Sep 10;13(13):1799-801. Unique Identifier : AIDSLINE MED/99437293
- Sheikh J; Souberbielle B; Westby M; Austen B; Dalgleish AG
- HIV-1 disease progression in women: role of the viral phenotype of the HIV-positive steady partner [letter]
- AIDS. 1999 Sep 10;13(13):1801-2. Unique Identifier : AIDSLINE MED/99437294
- Fiore JR; Buccoliero G; Pezzotti P; Rezza G; Saracino A; Pastore G; Fenyo EM; Angarano G
- Ritonavir-induced Cushing's syndrome in a patient treated with nasal fluticasone [letter]
- AIDS. 1999 Sep 10;13(13):1803. Unique Identifier : AIDSLINE MED/99437295
- Hillebrand-Haverkort ME; Prummel MF; ten Veen JH
- Detection of Epstein-Barr virus and human herpesvirus-8 DNA from Kaposi's sarcoma in patients with AIDS [letter]
- AIDS. 1999 Sep 10;13(13):1804-6. Unique Identifier : AIDSLINE MED/99437296
- Mastroianni A; Sabbatini AM; Portolani M; Cancellieri C
- Interaction of sildenafil and indinavir when co-administered to HIV-positive patients.
- AIDS. 1999 Oct 22;13(15):F101-7. Unique Identifier : AIDSLINE MED/20012342
- Merry C; Barry MG; Ryan M; Tjia JF; Hennessy M; Eagling VA; Mulcahy F; Back DJ; Department of Pharmacology and Therapeutics, Trinity Centre of; Health Sciences, St James's Hospital, Dublin, Ireland.
- OBJECTIVES: The prevalence of erectile dysfunction in HIV-infected men is estimated to be 33%. Sildenafil citrate (Viagra; Pfizer Ltd, Sandwich, Kent, UK) is the first oral drug for this condition. Since sildenafil and the p
- HIV-specific immunity following immunization with HIV synthetic envelope peptides in asymptomatic HIV-infected patients.
- AIDS. 1999 Oct 22;13(15):2003-12. Unique Identifier : AIDSLINE MED/20012343
- Pinto LA; Berzofsky JA; Fowke KR; Little RF; Merced-Galindez F; Humphrey R; Ahlers J; Dunlop N; Cohen RB; Steinberg SM; Nara P; Shearer GM; Yarchoan R; Experimental Immunology Branch, National Cancer Institute,; National Institutes of Health, Bethesda, Maryland 20892, USA.
- OBJECTIVE: A phase I trial was conducted to evaluate the safety and immunogenicity of an HIV synthetic peptide vaccine in HIV-seropositive individuals. The immunogens used in this study were PCLUS 3-18MN and PCLUS 6.1-18MN envelope peptides. METHODS: Eight HIV-infected patients received six subcutaneous injections of
- HIV-1 exposed dendritic cells show increased pro-inflammatory cytokine production but reduced IL-1ra following lipopolysaccharide stimulation.
- Unique Identifier : AIDSLINE MED/20012344 P P
- Lore K; Sonnerborg A; Olsson J; Patterson BK; Fehniger TE
- Expression and utilization of co-receptors in HIV and simian immunodeficiency virus infection of megakaryocytes.
- Unique Identifier : AIDSLINE MED/20012345
- Park IW; Wang JF; Groopman JE
- OBJECTIVE: To analyse the expression and specificity of co-receptors for the entry of HIV and simian immunodeficiency virus (SIV) into megakaryocytes. DESIGN AND METHODS: The expression of co-receptors was determined by flow cytometric analysis in combination with reverse transcription-polymerase chain (RT-PCR) reacti
- Enhanced HIV infectivity and changes in GP120 conformation associated with viral incorporation of human leucocyte antigen class I molecules.
- AIDS. 1999 Oct 22;13(15):2033-42. Unique Identifier : AIDSLINE MED/20012346
- Cosma A; Blanc D; Braun J; Quillent C; Barassi C; Moog C; Klasen S; Spire B; Scarlatti G; Pesenti E; Siccardi AG; Beretta A; Centre Integre de Recherches Biocliniques sur le SIDA, Paris,; France.
- BACKGROUND: Assembly of human immunodeficiency virus type 1 (HIV-1) occurs at the level of the plasma membrane of the host cell. During this process HIV incorporates significant quantities of cell surface-derived molecules into its lipid bilayer including human leucocyte antigen (HLA) class I and II, intercellular adh
- Functional and genetic integrity of the CD8 T-cell repertoire in advanced HIV infection.
- AIDS. 1999 Oct 22;13(15):2043-53. Unique Identifier : AIDSLINE MED/20012347
- Gamberg JC; Bowmer MI; Trahey JC; Campbell CM; Pardoe I; Grant MD; Immunology Program, Faculty of Medicine, Memorial University of; Newfoundland, St. John's, Canada.
- BACKGROUND: HIV-specific cytotoxic T lymphocytes (CTL) can restrict HIV replication in acute and chronic infection, but disease progression occurs in parallel with declining CTL activity. An understanding of why CTL fail to control HIV replication might reveal important mechanisms of disease progression and enhance pr
- HIV mediates a productive infection of the brain.
- Unique Identifier : AIDSLINE MED/20012348
- Wiley CA; Achim CL; Christopherson C; Kidane Y; Kwok S; Masliah E; Mellors J; Radhakrishnan L; Wang G; Soontornniyomkij V
- BACKGROUND: Approximately one quarter of patients with AIDS develop severe cognitive deficits called HIV-associated dementia complex. There is some controversy regarding the importance of viral load and distribution in mediating this neurologic disease. OBJECTIVE: Brain HIV provira
- Analysis of HIV cross-resistance to protease inhibitors using a rapid single-cycle recombinant virus assay for patients failing on combination therapies.
- AIDS. 1999 Oct 22;13(15):2061-8. Unique Identifier : AIDSLINE MED/20012349
- Race E; Dam E; Obry V; Paulous S; Clavel F; Laboratoire de Recherche Antivirale, Hopital Bichat-Claude; Bernard, Paris, France.
- OBJECTIVE: To assess the patterns of HIV phenotypic cross-resistance to protease inhibitors (PI) in patients experiencing viral load rebound on combination therapy including a PI. METHODS: Phenotypic analysis of sens
- Effectiveness of isoniazid chemoprophylaxis for HIV-infected drug users at high risk for active tuberculosis.
- AIDS. 1999 Oct 22;13(15):2069-74. Unique Identifier : AIDSLINE MED/20012350
- Gourevitch MN; Hartel D; Selwyn PA; Schoenbaum EE; Klein RS; Department of Epidemiology and Social Medicine, Montefiore; Medical Center, Albert Einstein College of Medicine, Bronx, New; York 10467, USA. mgourevi@montefiore.org
- OBJECTIVE: To define the effectiveness of chemoprophylaxis, outside of a clinical trial setting, in preventing tuberculosis among tuberculin-reactive and anergic HIV-infected drug users at high risk of developing active tuberculosis. DESIGN: An observational cohort study. SETTING: Methadone maintenance treatment progr
- Use of observational databases to evaluate the effectiveness of antiretroviral therapy for HIV infection: comparison of cohort studies with randomized trials. EuroSIDA, the French Hospital Database on HIV and the Swiss HIV Cohort Study Groups.
- AIDS. 1999 Oct 22;13(15):2075-82. Unique Identifier : AIDSLINE MED/20012351
- Phillips AN; Grabar S; Tassie JM; Costagliola D; Lundgren JD; Egger M; Royal Free Centre for HIV Medicine and Department of Primary Care; and Population Sciences, Royal Free and University College; Medical School, University College London, UK.
- OBJECTIVES: It is important to assess the extent of bias when comparing the clinical efficacy of antiretroviral regimens in observational databases because, with the current lack of planned large trials, such analyses may represent the only means of assessing the risk of serious clinical events associated with new reg
- The relationship between ritonavir plasma levels and side-effects: implications for therapeutic drug monitoring.
- AIDS. 1999 Oct 22;13(15):2083-9. Unique Identifier : AIDSLINE MED/20012352
- Gatti G; Di Biagio A; Casazza R; De Pascalis C; Bassetti M; Cruciani M; Vella S; Bassetti D; Department of Infectious Diseases, University of Genoa, Italy.; gigatti@smartino.ge.it
- OBJECTIVES: To assess whether the neurological or gastrointestinal adverse effects of ritonavir correlate with parameters of ritonavir systemic exposure. METHODS: Peak (Cmax) and trough (Cmin) ritonavir plasma levels were compared in 11 patients experiencing side-effects (group A) versus 10 patients without side-effec
- Effect of intrauterine device use on cervical shedding of HIV-1 DNA.
- AIDS. 1999 Oct 22;13(15):2091-7. Unique Identifier : AIDSLINE MED/20012353
- Richardson BA; Morrison CS; Sekadde-Kigondu C; Sinei SK; Overbaugh J; Panteleeff DD; Weiner DH; Kreiss JK; Department of Biostatistics, University of Washington, Seattle; 98195, USA.
- OBJECTIVE: Hormonal contraception has been associated with an increased prevalence of cervical shedding of HIV-1 DNA among infected women. We conducted this study to evaluate the effect of the use of an intrauterine device (IUD) on the detection of HIV-1 DNA in cervical secretions. DESIGN: A prospective study of HIV-1
- Recombinant human growth hormone improves the fat redistribution syndrome (lipodystrophy) in patients with HIV.
- AIDS. 1999 Oct 22;13(15):2099-103. Unique Identifier : AIDSLINE MED/20012354
- Wanke C; Gerrior J; Kantaros J; Coakley E; Albrecht M; Division of Infectious Disease, Beth Israel Deaconess Medical; Center, Harvard Medical School, Boston, MA, USA.; cwanke@infonet.tufts.edu
- OBJECTIVE: To determine the efficacy of recombinant human growth hormone (rhGH) in the treatment of the fat redistribution syndrome (FRS) in patients with HIV. DESIGN: A prospective, open-label study. SETTING: An urban, university-affiliated Infectious Disease Clinic. PATIENTS: Ten HIV-infected patients (seven men, th
- Highly active anti-retroviral therapy (HAART) prolongs time to treatment failure in Kaposi's sarcoma.
- AIDS. 1999 Oct 22;13(15):2105-11. Unique Identifier : AIDSLINE MED/20012355
- Bower M; Fox P; Fife K; Gill J; Nelson M; Gazzard B; Department of Oncology, Chelsea and Westminster Hospital, London,; UK. m.bower@cxwms.ac.uk
- OBJECTIVE: To evaluate the impact of highly active antiretroviral therapy (HAART) on Kaposi s sarcoma. DESIGN: Retrospective study of patients who had received systemic or local treatment for AIDS-related Kaposi s sarcoma who subsequently commenced HAART. METHODS: Case note review to determine time to treatment failur
- Relative risks and population attributable fraction of incident HIV associated with symptoms of sexually transmitted diseases and treatable symptomatic sexually transmitted diseases in Rakai District, Uganda. Rakai Project Team.
- AIDS. 1999 Oct 22;13(15):2113-23. Unique Identifier : AIDSLINE MED/20012356
- Gray RH; Wawer MJ; Sewankambo NK; Serwadda D; Li C; Moulton LH; Lutalo T; Wabwire-Mangen F; Meehan MP; Ahmed S; Paxton LA; Kiwanuka N; Nalugoda F; Korenromp EL; Quinn TC; Department of Population and Family Health Sciences, School of; Hygiene and Public Health, Johns Hopkins University, Baltimore,; Maryland 21205, USA.
- OBJECTIVES: To assess the linkage of sexually transmitted disease (STD) symptoms and treatable STD to HIV incidence. DESIGN: Analysis of a randomized trial of STD control for HIV prevention, Rakai, Uganda . METHODS: Consenting adults 15-59 years of age were seen at 10-monthly home v
- Changes in survival among people with AIDS in Lazio, Italy from 1993 to 1998. Lazio AIDS Surveillance Collaborative Group [see comments]
- AIDS. 1999 Oct 22;13(15):2125-31. Unique Identifier : AIDSLINE MED/20012357
- Porta D; Rapiti E; Forastiere F; Pezzotti P; Perucci CA; Epidemiology Department Lazio Region, Rome, Italy.
- OBJECTIVES: To investigate temporal changes in survival of persons with AIDS (PWA) diagnosed in Lazio, Italy . DESIGN: Longitudinal study of 2862 PWA registered at the AIDS Surveillance System in the period 1 January 1993 to 30 June 1997 and followed for vital status up to 31 May 199
- Reduced fertility associated with HIV: the contribution of pre-existing subfertility.
- AIDS. 1999 Oct 22;13(15):2133-41. Unique Identifier : AIDSLINE MED/20012358
- Ross A; Morgan D; Lubega R; Carpenter LM; Mayanja B; Whitworth JA; Medical Research Council Programme on AIDS in Uganda, Uganda; Virus Research Institute, Entebbe.
- BACKGROUND: HIV-1 infection is associated with lower fertility among women in sub-Saharan Africa and this association is not explained by the frequency of sexual intercourse, illness, knowledge of HIV status or infection with other sexually transmitted diseases. Women with fertility problems are at increased risk of m
- Frequent detection of HIV-1 in the gastric aspirates of neonates born to HIV-infected mothers.
- AIDS. 1999 Oct 22;13(15):2143-9. Unique Identifier : AIDSLINE MED/20012359
- Mandelbrot L; Burgard M; Teglas JP; Benifla JL; Khan C; Blot P; Vilmer E; Matheron S; Firtion G; Blanche S; Mayaux MJ; Rouzioux C; Service de Gynecologie-Obstetrique I, Centre Hospitalier; Universitaire Cochin-Port Royal, Paris, France.
- OBJECTIVE: To evaluate the frequency and correlates of oral route exposure of infants born to HIV-1-infected women. METHODS: A multicenter study was performed within the prospective French Perinatal Cohort Study of mother-to-child HIV transmission. Oropharyngeal and gastric aspirates from 122 neonates were studied by
- Changes in HIV-related risk behaviors following drug abuse treatment.
- AIDS. 1999 Oct 22;13(15):2151-5. Unique Identifier : AIDSLINE MED/20012360
- Woods WJ; Guydish JR; Sorensen JL; Coutts A; Bostrom A; Acampora A; Department of Medicine, University of California San Francisco,; 94105, USA. bwoods@psg.ucsf.edu
- OBJECTIVES: To measure changes in HIV-related injection drug and sexual risk behaviors following drug treatment in a therapeutic community program. METHODS: We conducted a prospective cohort study of 261 drug users, randomly assigned to day or residential treatment. Participants were interviewed 2 weeks after entering
- Decreased morbidity and use of hospital services in English HIV-infected individuals with increased uptake of anti-retroviral therapy 1996-1997. National Prospective Monitoring System Steering Group.
- AIDS. 1999 Oct 22;13(15):2157-64. Unique Identifier : AIDSLINE MED/20012361
- Beck EJ; Mandalia S; Williams I; Power A; Newson R; Molesworth A; Barlow D; Easterbrook P; Fisher M; Innes J; Kinghorn G; Mandel B; Pozniak A; Tang A; Tomlinson D; NPMS Coordinating and Analytic Centre, Chelsea and Westminster; Hospital, London, UK. e.beck@ic.ac.uk
- OBJECTIVE: To investigate the relationship between changing morbidity patterns, the use of hospital services by HIV-infected patients and the uptake of antiretroviral therapy (ART) in England. DESIGN: Prospective serial cross-sectional analyses based on data collected through the National Prospective Monitoring System
- Assessing the impact of highly active antiretroviral therapy on AIDS and death [editorial; comment]
- AIDS. 1999 Oct 22;13(15):2165-6. Unique Identifier : AIDSLINE MED/20012362
- Sabin CA
- Report of gynecomastia in five male patients during antiretroviral therapy for HIV infection [letter]
- AIDS. 1999 Oct 22;13(15):2167-9. Unique Identifier : AIDSLINE MED/20012363
- Peyriere H; Mauboussin JM; Rouanet I; Merle C; Sotto A; Arnaud A; Hillaire-Buys D; Balmes P
- Seminal plasma RANTES levels positively correlate with seminal plasma HIV-1 RNA levels [letter]
- Unique Identifier : AIDSLINE MED/20012364
- Storey DF; Dolan MJ; Anderson SA; Meier PA; Walter EA
- Prolonged therapy with the fusion inhibitor T-20 in combination with oral antiretroviral agents in an HIV-infected individual [letter]
- AIDS. 1999 Oct 22;13(15):2171-3. Unique Identifier : AIDSLINE MED/20012365
- Pilcher CD; Eron JJ Jr; Ngo L; Dusek A; Sista P; Gleavy J; Brooks D; Venetta T; DiMassimo E; Hopkins S
- Nephropathy and renal colic in patients treated with indinavir, ritonavir plus indinavir or ritonavir plus saquinavir [letter]
- AIDS. 1999 Oct 22;13(15):2173-4. Unique Identifier : AIDSLINE MED/20012366
- Padberg J; Fritsche L; Bergmann F; Schurmann D; Suttorp N
- Oral hairy leukoplakia and oral candidiasis as predictors of HIV viral load [letter]
- AIDS. 1999 Oct 22;13(15):2174-6. Unique Identifier : AIDSLINE MED/20012367
- Patton LL; McKaig RG; Eron JJ Jr; Lawrence HP; Strauss RP
- Combination therapy with alpha interferon and lamivudine in patients with chronic hepatitis B and HIV infection [letter]
- AIDS. 1999 Oct 22;13(15):2176-8. Unique Identifier : AIDSLINE MED/20012368
- Nasti G; di Gennaro G; Donada C; Donadon V; Tirelli U
- Interleukin 1beta induces expression of human herpesvirus 8 encoded genes in BCBL-1 cells [letter]
- AIDS. 1999 Oct 22;13(15):2178-80. Unique Identifier : AIDSLINE MED/20012369
- Yu Y; Roan F; Offermann MK
- What dual protease inhibitor combination for salvage therapies? [letter]
- AIDS. 1999 Oct 22;13(15):2180-1. Unique Identifier : AIDSLINE MED/20012370
- Rodriguez-Rosado R; Soriano V; Barreiro P; Dona C; Gonzalez-Lahoz J
- Ingrown toenail and indinavir: case-control study demonstrates strong relationship [letter]
- AIDS. 1999 Oct 22;13(15):2181-2. Unique Identifier : AIDSLINE MED/20012371
- Bourezane Y; Thalamy B; Viel JF; Bardonnet K; Drobacheff C; Gil H; Vuitton DA; Hoen B
- Frequency of HIV false positivity from two sequential enzyme immunoassays in 111 639 sera [letter]
- AIDS. 1999 Oct 22;13(15):2182-3. Unique Identifier : AIDSLINE MED/20012372
- Chanbancherd P; Jugsudee A; Thanomklom S; Limpairojn N; Julananto P; Thienamporn P; Markowitz LE; de Souza MS; Brown AE
- Genetic diversity of HIV-1 subtype F from Brazil: failure of HIV-1 viral load testing based on molecular biology amplification methods [letter]
- AIDS. 1999 Oct 22;13(15):2183-5. Unique Identifier : AIDSLINE MED/20012373
- Mercado JM; Di Dio R; Pradal MG
- Localized Mycobacterium avium intracellulare psoas abscess in patients with AIDS after antiretroviral therapy [letter]
- AIDS. 1999 Oct 22;13(15):2185-6. Unique Identifier : AIDSLINE MED/20012374
- Boyd AE; Brettle RP
- Hydroxyurea reduces the 50% inhibitory concentration of didanosine in HIV-infected cells [letter]
- AIDS. 1999 Oct 22;13(15):2186-8. Unique Identifier : AIDSLINE MED/20012375
- Rana KZ; Simmons KA; Dudley MN
- The effects of discontinuing stavudine therapy on clinical and metabolic abnormalities in patients suffering from lipodystrophy [letter]
- AIDS. 1999 Oct 22;13(15):2188-9. Unique Identifier : AIDSLINE MED/20012376
- Saint-Marc T; Touraine JL
- Screening people living with HIV before tuberculosis preventative therapy [letter]
- AIDS. 1999 Oct 22;13(15):2190-1. Unique Identifier : AIDSLINE MED/20012377
- Godfrey-Faussett P; Quigley M; Ayles H; Mwinga A; Hosp M; Porter J
- The significance of bacteremic tuberculosis among persons with HIV infection in developing countries [editorial]
- AIDS. 1999 Nov 12;13(16):2193-5. Unique Identifier : AIDSLINE MED/20025228
- von Reyn CF
- HIV type 1 envelope glycoprotein gp120 induces development of a T helper type 2 response to Cryptococcus neoformans.
- AIDS. 1999 Nov 12;13(16):2197-207. Unique Identifier : AIDSLINE MED/20025229
- Pietrella D; Monari C; Retini C; Palazzetti B; Kozel TR; Vecchiarelli A; Department of Experimental Medicine and Biochemical Sciences,; University of Perugia, Italy.
- OBJECTIVE: To analyse the contribution of HIV type 1 envelope glycoprotein gp120 to regulation of a T-cell response to Cryptococcus neoformans. DESIGN: Monocytes treated with recombinant gp120 and exposed to C. neoformans were used as antigen presenting cells (APC) in coculture with autologous T lymphocytes. METHODS:
- A randomized trial comparing regimens of four reverse transcriptase inhibitors given together or cyclically in HIV-1 infection--the Quattro Trial. Quattro Steering Committee.
- AIDS. 1999 Nov 12;13(16):2209-17. Unique Identifier : AIDSLINE MED/20025230
- OBJECTIVES: To assess if cyclical therapy with four reverse transcriptase inhibitors is less toxic and as active, based on virological and immunological markers, as the same four drugs given together over a 64-week period. METHODS: An open randomized trial comparing concurrent therapy (T4) with zidovudine, lamivudine,
- Lymph node architecture preceding and following 6 months of potent antiviral therapy: follicular hyperplasia persists in parallel with p24 antigen restoration after involution and CD4 cell depletion in an AIDS patient.
- AIDS. 1999 Nov 12;13(16):2219-29. Unique Identifier : AIDSLINE MED/20025231
- Orenstein JM; Feinberg M; Yoder C; Schrager L; Mican JM; Schwartzentruber DJ; Davey RT Jr; Walker RE; Falloon J; Kovacs JA; Miller KD; Fox C; Metcalf JA; Masur H; Polis MA; Department of Pathology, George Washington University Medical; Center, Washington, DC 20037, USA. patjmo@gwumc.edu
- OBJECTIVES: To evaluate changes in architecture, viral RNA, and viral protein over 6 months in lymph nodes from retroviral-naive HIV-infected persons before and after commencing highly active antiretroviral therapy (HAART). METHODS: Nine antiretroviral-naive HIV-infected persons had lymph nodes excised at baseline and
- Sustained plasma TNF-alpha and HIV-1 load despite resolution of other parameters of immune activation during treatment of tuberculosis in Africans.
- AIDS. 1999 Nov 12;13(16):2231-7. Unique Identifier : AIDSLINE MED/20025232
- Lawn SD; Shattock RJ; Acheampong JW; Lal RB; Folks TM; Griffin GE; Butera ST; HIV and Retrovirology Branch, Centers for Disease Control and; Prevention, Public Health Service, U.S. Department of Health and; Human Services, Atlanta, Georgia 30333, USA.
- OBJECTIVE: To determine the impact of treatment of tuberculosis on plasma HIV-1 load in African subjects and to correlate viral load with response to treatment and changes in immune activation. DESIGN: Clinical and microbiological responses, immune activation parameters and plasma HIV-1 load were determined in 20 pati
- The pharmacokinetics of lamivudine phosphorylation in peripheral blood mononuclear cells from patients infected with HIV-1.
- AIDS. 1999 Nov 12;13(16):2239-50. Unique Identifier : AIDSLINE MED/20025233
- Moore KH; Barrett JE; Shaw S; Pakes GE; Churchus R; Kapoor A; Lloyd J; Barry MG; Back D; Glaxo Wellcome Research and Development, Greenford, UK.
- OBJECTIVE: To assess the pharmacokinetics of lamivudine phosphorylation in peripheral blood mononuclear cells (PBMC) from patients infected with HIV-1. DESIGN: Single-center, open-label, randomized, two-period, cross-over study in 10 asymptomatic, antiretroviral-experienced, HIV-1-infected patients who had a CD4+ lymp
- Lipodystrophy defined by a clinical score in HIV-infected men on highly active antiretroviral therapy: correlation between dyslipidaemia and steroid hormone alterations.
- AIDS. 1999 Nov 12;13(16):2251-60. Unique Identifier : AIDSLINE MED/20025234
- Christeff N; Melchior JC; de Truchis P; Perronne C; Nunez EA; Gougeon ML; URA CNRS 1930, Departement SIDA et Retrovirus, Institut Pasteur,; Paris, France.
- BACKGROUND: A syndrome of lipodystrophy, associated with hypertriglyceridaemia, hypercholesterolaemia, hyperinsulinaemia and peripheral insulin resistance has been reported in protease inhibitor (PI)-treated HIV-infected patients. Because lipid metabolism, fat mass distribution and insulin resistance are partly regula
- Subcutaneous adipocyte apoptosis in HIV-1 protease inhibitor-associated lipodystrophy.
- AIDS. 1999 Nov 12;13(16):2261-7. Unique Identifier : AIDSLINE MED/20025235
- Domingo P; Matias-Guiu X; Pujol RM; Francia E; Lagarda E; Sambeat MA; Vazquez G; Department of Internal Medicine, Hospital de la Santa Creu i Sant; Pau, Universitat Autonoma de Barcelona, Spain.; pere.domingo@cc.uab.es
- BACKGROUND: Inhibitors of HIV-1 protease produce a rapid decrease in plasma HIV-1 RNA, with concomitant immune reconstitution. However, severe metabolic side effects together with a previously unseen form of lipodystrophy have been associated with long-term use of protease-inhibitor therapy. The pathogenic mechanisms
- The contribution of assay variation and biological variation to the total variability of plasma HIV-1 RNA measurements. The Women Infant Transmission Study Clinics. Virology Quality Assurance Program.
- AIDS. 1999 Nov 12;13(16):2269-79. Unique Identifier : AIDSLINE MED/20025236
- Brambilla D; Reichelderfer PS; Bremer JW; Shapiro DE; Hershow RC; Katzenstein DA; Hammer SM; Jackson B; Collier AC; Sperling RS; Fowler MG; Coombs RW; New England Research Institute, Watertown, MA 02472, USA.
- OBJECTIVES: To assess the specific contributions of assay variation and biological variation to the total variation of plasma HIV-1 RNA measured by the Roche Monitor assay and the extent to which batch assays reduced both assay variability and total variability compared with real-time determinations. DESIGN: A retrosp
- Regional survival differences across Europe in HIV-positive people: the EuroSIDA study.
- AIDS. 1999 Nov 12;13(16):2281-8. Unique Identifier : AIDSLINE MED/20025237
- Chiesi A; Mocroft A; Dally LG; Miller V; Katlama C; Ledergerber B; Pedersen C; Phillips AN; Arcieri R; Lundgren JD; Istituto Superiore di Sanita', Rome, Italy.
- OBJECTIVES: To analyse the survival differences between macro-regions of Europe (northern, central and southern Europe) between 1994 and early 1999, and their possible association with antiretroviral treatment differences. DESIGN: From September 1994 the EuroSIDA study has prospectively followed non-selected HIV-infec
- HIV treatments optimism and sexual behaviour among gay men in Sydney and Melbourne.
- Unique Identifier : AIDSLINE MED/20025238 P P
- Van de Ven P; Kippax S
- Risk perception and HIV-1 prevalence in 15,000 adults in rural south-west Uganda.
- AIDS. 1999 Nov 12;13(16):2295-302. Unique Identifier : AIDSLINE MED/20025239
- Kengeya-Kayondo JF; Carpenter LM; Kintu PM; Nabaitu J; Pool R; Whitworth JA; Medical Research Council (UK) Programme on AIDS in Uganda, Uganda; Virus Research Institute, Entebbe.
- OBJECTIVE: Few studies have described levels and determinants of perceived risk of HIV-1 among African adults for whom the sero-status is known. This study describes HIV risk perception obtained from a large rural population in south-west Uganda which also underwent serological tes
- Recent increases in HIV seroconversion among repeat anonymous testers in San Francisco [letter]
- AIDS. 1999 Nov 12;13(16):2303-4. Unique Identifier : AIDSLINE MED/20025240
- Kellogg T; McFarland W; Katz M
- Indication for increasing prevalence of resistance mutations for protease inhibitors in therapy-naive HIV-1-positive German patients [letter]
- AIDS. 1999 Nov 12;13(16):2304-5. Unique Identifier : AIDSLINE MED/20025241
- Dietrich U; Raudonat I; Wolf E; Jager H; Husak R; Orfanos CE; Knickmann M; Knechten H; von Briesen H; Ruppach H; Immelmann A
- Frozen shoulder in HIV patients treated with indinavir: report of three cases [letter]
- AIDS. 1999 Nov 12;13(16):2305-6. Unique Identifier : AIDSLINE MED/20025242
- Peyriere H; Mauboussin JM; Rouanet I; Rouveroux P; Hillaire-Buys D; Balmes P
- Prednisolone does not prevent the occurrence of nevirapine-induced rashes [letter]
- AIDS. 1999 Nov 12;13(16):2307. Unique Identifier : AIDSLINE MED/20025243
- Rey D; Partisani M; Krantz V; Kempf G; Nicolle M; de Mautort E; Priester M; Bernard-Henry C; Lang JM
- High circulating levels of soluble CD30 correlate with impaired delayed-type hypersensitivity responses in HIV-infected patients [letter]
- AIDS. 1999 Nov 12;13(16):2308-9. Unique Identifier : AIDSLINE MED/20025244
- Price P; Murray RJ; John M; French MA
- Severe anemia as a newly recognized side-effect caused by lamivudine [letter]
- AIDS. 1999 Nov 12;13(16):2309-11. Unique Identifier : AIDSLINE MED/20025245
- Weitzel T; Plettenberg A; Albrecht D; Lorenzen T; Stoehr A
- Nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity as an etiology for lipodystrophy [letter]
- AIDS. 1999 Nov 12;13(16):2311-2. Unique Identifier : AIDSLINE MED/20025246
- Kakuda TN; Brundage RC; Anderson PL; Fletcher CV
- Visceral obesity, hypertriglyceridemia and hypercortisolism in a boy with perinatally acquired HIV infection receiving protease inhibitor-containing antiviral treatment [letter]
- AIDS. 1999 Nov 12;13(16):2312-3. Unique Identifier : AIDSLINE MED/20025247
- Arpadi SM; Cuff PA; Horlick M; Kotler DP
- Family issues in HIV-infected haemophilic patients [letter]
- AIDS. 1999 Nov 12;13(16):2314-5. Unique Identifier : AIDSLINE MED/20025248
- Yee TT; Goldman E; Devereux H; Sabin C; Lee CA
- Silicones, hormones and HIV in transgender street prostitutes [letter]
- AIDS. 1999 Nov 12;13(16):2315-6. Unique Identifier : AIDSLINE MED/20025249
- Wiessing LG; van Roosmalen MS; Koedijk P; Bieleman B; Houweling H
- Advances in the medical management of patients with HIV-1 infection: an overview.
- AIDS. 1999 Sep;13 Suppl 1:S1-9. Unique Identifier : AIDSLINE MED/20012271
- Volberding PA; San Francisco General Hospital, UCSF AIDS Program, California; 94110, USA. pvolberding@PHP.UCSF.edu
- New guidelines for the management of patients with HIV-1 infection emphasize early aggressive treatment using multi-drug combination regimens. Accurate assessment of the effectiveness of these treatments and their potential (small as it now seems) to eradicate HIV-1 infection requires testing for viral levels in the b
- Viral kinetics: implications for treatment.
- AIDS. 1999 Sep;13 Suppl 1:S11-7. Unique Identifier : AIDSLINE MED/20012272
- Young B; Kuritzkes DR; Division of Infectious Diseases, University of Colorado Health; Sciences Center, Denver, USA. denveridc@aol.com
- Increasing knowledge of the principles of viral dynamics in HIV infection has dramatically changed our understanding of the disease. Basic concepts of viral kinetics and implications for the treatment of HIV-infected persons are reviewed.
- HIV protease inhibitors: immunological insights.
- AIDS. 1999 Sep;13 Suppl 1:S19-27. Unique Identifier : AIDSLINE MED/20012273
- Mitsuyasu R; University of California at Los Angeles CARE Center, USA.
- Regimens of highly active antiretroviral therapy (HAART), including those containing one or more of the potent HIV protease inhibitors , often cause large increases in CD4 cell count as well as large decreases in plasma HIV RNA that persist over time. Patients improv
- HIV protease inhibitors: pharmacologic and metabolic distinctions.
- AIDS. 1999 Sep;13 Suppl 1:S29-40. Unique Identifier : AIDSLINE MED/20012274
- Sommadossi JP; Department of Clinical Pharmacology, Center for AIDS Research,; University of Alabama at Birmingham, School of Medicine,; 35294-0019, USA.
- In the earlier era of nucleoside analogue antiretroviral therapy, considerations of pharmacologic drug-drug interactions were only a small factor in choosing optimal therapies for patients with HIV infection. However, pharmacologic considerations are critical for selecting and managing the current multiple-drug antire
- Nelfinavir, a new protease inhibitor: early clinical results.
- AIDS. 1999 Sep;13 Suppl 1:S41-8. Unique Identifier : AIDSLINE MED/20012275
- Powderly WG; Tebas P; Division of Infectious Diseases, Washington University School of; Medicine, St Louis, Missouri 63110, USA.; wpowderl@imgate.wustl.edu
- Nelfinavir is a potent inhibitor of the HIV-1 protease, which shows good inhibitory activity against HIV-1 in vitro. Initial clinical trials have shown that it has excellent activity in vivo in HIV-infected patients. The combination of 750 mg nelfinavir three times daily with zidovudine and lamivudine has been shown t
- Antiretroviral therapy in 1999 for antiretroviral-naive individuals with HIV infection.
- AIDS. 1999 Sep;13 Suppl 1:S49-59. Unique Identifier : AIDSLINE MED/20012276
- Fischl MA; University of Miami School of Medicine, AIDS Clinical Research; Unit, Florida 33101, USA.
- The choice of initial antiretroviral regimen for treating people infected with HIV is crucial to successful long-term control of virus replication. Potent antiretroviral therapy substantially suppresses viral replication as measured by plasma HIV RNA levels to below limits of detection: the current standard of care is
- Attaining higher goals in HIV treatment: the central importance of adherence.
- AIDS. 1999 Sep;13 Suppl 1:S61-72. Unique Identifier : AIDSLINE MED/20012277
- Friedland GH; Williams A; AIDS Program, Yale University School of Medicine, New Haven,; Connecticut 06437, USA. gerald.Freidland!@yale.edu
- In recent years, advances in HIV therapeutics have changed the nature of HIV/AIDS disease, so that it has now assumed some of the characteristics of a chronic disease. Several factors have, however, qualified these advances. Social, economic, and clinical variables have confounded universal therapeutic success. Acce
- Quiz case 2. Coccidioidomycosis.
- Arch Otolaryngol Head Neck Surg. 1999 Oct;125(10):1159, 1161-2. Unique Identifier : AIDSLINE MED/99450347
- Spiegel JH; Sudilovsky D
- Allergic networks regulating eosinophilia [comment]
- Am J Respir Cell Mol Biol. 1999 Oct;21(4):451-4. Unique Identifier : AIDSLINE MED/99433893
- Foster PS; Division of Biochemistry and Molecular Biology, John Curtin; School of Medical Research, Australian National University,; Canberra, ACTON ACT, Australia. Paul.Foster@anu.edu.au
- Expression of monocyte chemotactic protein (MCP)-1, MCP-2, and MCP-3 by human airway smooth-muscle cells. Modulation by corticosteroids and T-helper 2 cytokines.
- Am J Respir Cell Mol Biol. 1999 Oct;21(4):528-36. Unique Identifier : AIDSLINE MED/99433902
- Pype JL; Dupont LJ; Menten P; Van Coillie E; Opdenakker G; Van Damme J; Chung KF; Demedts MG; Verleden GM; Laboratory of Pneumology, Laboratory of Molecular Immunology,; Rega Institute, Katholieke Universiteit, Leuven, Belgium.
- We have demonstrated that, in addition to their contractile function, human airway smooth-muscle cells (HASMC) are able to express and to secrete chemokines of the monocyte chemotactic protein (MCP)/ eotaxin subfamily. This group of chemokines is believed to play a fundamental role in the development of allergic airwa
- [Meningitis by Cryptococcus neoformans in patients with HIV infection]
- Neurologia. 1999 May;14(5):218-23. Unique Identifier : AIDSLINE MED/99305485
- Martinez Fernandez EM; Lopez-Cortes LF; Regordan C; Cordero Matia E; Servicio de Neurologia, Hospital Universitario Virgen del; Rocio, Sevilla. evamtnez@arrakis.es
- OBJECTIVE: To review a serie of patients with cryptococcal meningitis and immunodeficiency syndrome (AIDS) treated in our hospital in the last two years. PATIENTS AND METHODS: Retrospective study of 25 patients infected with the human immunodeficiency virus (HIV) and affected by Cryptococcus neoformans meningitis. The
- Using cross-cultural input to adapt the Functional Assessment of Chronic Illness Therapy (FACIT) scales.
- Acta Oncol. 1999;38(6):695-702. Unique Identifier : AIDSLINE MED/99450594
- Lent L; Hahn E; Eremenco S; Webster K; Cella D; Center on Outcomes, Research and Education, Evanston Northwestern; Healthcare, Evanston, IL 60201, USA.
- Cross-cultural quality of life measurement and psychosocial assessment in oncology have become reality with the translation and international validation of quality of life questionnaires. The Functional Assessment of Chronic Illness Therapy (FACIT) Measurement System, under development since 1987, produced its 4th ver
- Controlled management of public relations following a public health incident.
- J Public Health Med. 1999 Sep;21(3):251-4. Unique Identifier : AIDSLINE MED/99456219
- Holdsworth GM; Breathnach A; Asboe D; Free D; Cranston R; Peters BS; de Ruiter A; Department of Public Health and Health Policy, Lambeth, Southwark; and Lewisham Health Authority, London.
- This paper describes the management of public relations following an outbreak of multidrug resistant TB at a London hospital. Eight patients were involved, all of the secondary cases occurred in HIV seropositive patients, and three cases died. The paper describes how the the Incident Committee undertook to recall cont
- What is the cost of getting the price wrong?
- J Public Health Med. 1999 Sep;21(3):311-7. Unique Identifier : AIDSLINE MED/99456227
- Beck EJ; Beecham J; Mandalia S; Griffith R; Walters MD; Boulton M; Miller DL; Department of Epidemiology and Public Health, Imperial College; School of Medicine, London.
- BACKGROUND: The objective of this study was to compare differences in cost estimates for paediatric HIV hospital service provision based on hospital prices with cost estimates obtained through a research-based service-specific costing exercise. METHODS: Activity data on the use of hospital services of children by stag
- Quarterly communicable disease review January to March 1999. From the PHLS Communicable Disease Surveillance Centre. Public Health Laboratory Service.
- J Public Health Med. 1999 Sep;21(3):348-54. Unique Identifier : AIDSLINE MED/99456232
- Catchpole M; Hamilton G; Hawker J; Olowokure B; Ramsay M; Weinberg J; Weild A
- Characteristic distribution of HTLV type I and HTLV type II carriers among native ethnic groups in South America.
- AIDS Res Hum Retroviruses. 1999 Sep 20;15(14):1235-9. Unique Identifier : AIDSLINE MED/99433490
- Fujiyoshi T; Li HC; Lou H; Yashiki S; Karino S; Zaninovic V; Oneegllo SG; Camacho M; Andrade R; Hurtado LV; Gomez LH; Damiani E; Cartier L; Dipierri JE; Hayami M; Sonoda S; Tajima K; Department of Virology, Faculty of Medicine, Kagoshima; University, Japan.
- To confirm the geographic and ethnic segregation of HTLV-I and HTLV-II carriers in native populations in South America, we have conducted a seroepidemiological study of native populations in South America, including HTLV-I carriers distributed among seven ethnic groups in the Andes highlands of
- Chloroquine exerts an additive in vitro anti-HIV type 1 effect when associated with didanosine and hydroxyurea.
- AIDS Res Hum Retroviruses. 1999 Sep 20;15(14):1241-7. Unique Identifier : AIDSLINE MED/99433491
- Boelaert JR; Sperber K; Piette J; Unit for Renal and Infectious Diseases, Algemeen Ziekenhuis; St-Jan, Brugge, Belgium. j.r.boelaert.brugge@unicall.be
- Several groups, including ours, have reported that chloroquine (CQ) or its analog hydroxychloroquine has anti-HIV-1 activity both in vitro and in vivo. We studied in vitro whether the addition of CQ to the combination of hydroxyurea (HU) plus didanosine (ddI) had an additive effect in inhibiting the replication of HIV
- Long-term effects of antiretroviral combination therapy on HIV type 1 DNA levels.
- AIDS Res Hum Retroviruses. 1999 Sep 20;15(14):1249-54. Unique Identifier : AIDSLINE MED/99433492
- Aleman S; Visco-Comandini U; Lore K; Sonnerborg A; Division of Clinical Virology, Institution of Immunology,; Microbiology, Pathology, and Infectious Diseases, Karolinska; Institute, Huddinge University Hospital, Huddinge/Stockholm,; Sweden.
- HIV-1 RNA and DNA levels were measured in 58 patients, of whom 37 and 11, respectively, received triple or double combination therapy . At baseline, strong correlations were found between the number of HIV-1 DNA copies per 106 CD4+ cells, the plasma HIV-1 RNA levels, an
- The cell death-inducing ability of glycoprotein 120 from different HIV strains correlates with their ability to induce CD4 lateral association with CD95 on CD4+ T cells.
- AIDS Res Hum Retroviruses. 1999 Sep 20;15(14):1255-63. Unique Identifier : AIDSLINE MED/99433493
- Bottarel F; Feito MJ; Bragardo M; Bonissoni S; Buonfiglio D; DeFranco S; Malavasi F; Bensi T; Ramenghi U; Dianzani U; Department of Medical Sciences, A. Avogadro University of Eastern; Piedmont at Novara, Italy.
- CD4 cross-linking by HIV gp120 triggers CD4+ T cell death. Several authors have suggested that this effect is mediated by CD95, but this possibility is debated by other authors. In a previous work, we found by co-capping that gp120(451) and gp120MN, but not gp120(IIIB), induce lateral association of CD4 with CD95 on t
- Effect of extracellular human immunodeficiency virus type 1 glycoprotein 120 on primary human vascular endothelial cell cultures.
- AIDS Res Hum Retroviruses. 1999 Sep 20;15(14):1265-77. Unique Identifier : AIDSLINE MED/99433494
- Huang MB; Hunter M; Bond VC; Department of Biochemistry, Morehouse School of Medicine,; Atlanta, Georgia 30087-1495, USA.
- During the course of an HIV-1 infection, free infectious and noninfectious virus particles, and free HIV-1 proteins, circulate within the host, exposing the host endothelium to these viral factors, even if the endothelium is not infected. This suggests that extracellular HIV-1 proteins could influence endothelial cell
- Chemokine pattern in relation to disease state in human immunodeficiency virus-infected children.
- AIDS Res Hum Retroviruses. 1999 Sep 20;15(14):1279-85. Unique Identifier : AIDSLINE MED/99433495
- Than S; Tumaliuan JA; Tamma S; Morales M; Bakshi S; Pahwa S; Department of Pediatrics, North Shore University Hospital-New; York University School of Medicine, Manhasset 11030, USA.
- Although beta chemokines can block human immunodeficiency virus (HIV) entry into target cells, their role in HIV disease progression is controversial. To determine the association of RANTES with HIV disease state, we examined constitutive mRNA expression by reverse-transcribed polymerase chain reaction (RT-PCR) in per
- Rapid detection of the HIV type 1 reverse transcriptase codon T215Y by reverse transcription-polymerase chain reaction with fluorogenic probes.
- AIDS Res Hum Retroviruses. 1999 Sep 20;15(14):1287-92. Unique Identifier : AIDSLINE MED/99433496
- Ross L; Vavro C; Zimmermann A; St. Clair M; Department of Virology, Glaxo Wellcome, Research Triangle Park,; North Carolina 27709, USA. llr8156@glaxowellcome.com
- Early detection of viral mutations, particularly those mutations associated with cross-resistance to antiretroviral drugs, is critical both for understanding the mechanism of drug resistance and for the clinical management of patients infected with HIV-1. One of the frequently observed mutations in the HIV-1 reverse t
- Long terminal repeat promoter/enhancer activity of different subtypes of HIV type 1.
- AIDS Res Hum Retroviruses. 1999 Sep 20;15(14):1293-303. Unique Identifier : AIDSLINE GENBANK/AF102226
- Naghavi MH; Schwartz S; Sonnerborg A; Vahlne A; Department of Immunology, Microbiology, Pathology, and Infectious; Diseases, Karolinska Institute, Huddinge University Hospital,; Huddinge/Stockholm, Sweden. muna@lab01.hs.sll.se
- Transcription of the HIV-1 provirus genome is regulated by a complex interplay between viral regulatory proteins and cellular transcription factors that interact with the viral long terminal repeat (LTR) region of HIV-1. However, several cellular transcription factors have been identified that can interact with the HI
- The dendritic cell-T cell milieu of the lymphoid tissue of the tonsil provides a locale in which SIV can reside and propagate at chronic stages of infection.
- AIDS Res Hum Retroviruses. 1999 Sep 20;15(14):1305-14. Unique Identifier : AIDSLINE MED/99433498
- Hu J; Miller CJ; O'Doherty U; Marx PA; Pope M; California Regional Primate Research Center, University of; California, Davis 95616, USA.
- Previous studies described the presence of numerous human immunodeficiency virus (HIV)-positive cells within and just beneath the mucosal surfaces of the tonsillar tissue of HIV-1-infected individuals. The virus-positive cells were most abundant in the dendritic cell (DC)-T cell rich areas of the lymphoepithelia linin
- Sequences and predicted structures of chimpanzee STRL33 (Bonzo) and gpr15 (BOB).
- AIDS Res Hum Retroviruses. 1999 Sep 20;15(14):1315-9. Unique Identifier : AIDSLINE MED/99433499
- Brussel A; Pretet JL; Girard M; Butor C; Laboratoire d'Immunologie des Pathologies Infectieuses et; Tumorales, INSERM U445, Institut Cochin de Genetique; Moleculaire, Universite Rene Decartes, Paris, France.
- An infectious DNA clone of HIV type 1 subtype C.
- AIDS Res Hum Retroviruses. 1999 Sep 20;15(14):1321-4. Unique Identifier : AIDSLINE GENBANK/AB023804
- Mochizuki N; Otsuka N; Matsuo K; Shiino T; Kojima A; Kurata T; Sakai K; Yamamoto N; Isomura S; Dhole TN; Takebe Y; Matsuda M; Tatsumi M; Department of Pathology, Research Institute, International; Medical Center of Japan, Toyama, Tokyo.
- Among the 10 subtypes of the M group of human immunodeficiency virus type 1, subtype C is the most prevalent in India and may dominate worldwide in the near future; however, there has been no report on the infectious DNA clone of this subtype. We have isolated an infectious DNA clon
- Inhibition of telomerase activity and cell proliferation by a reverse transcriptase inhibitor in gynaecological cancer cell lines.
- Eur J Cancer. 1999 Jun;35(6):1027-34. Unique Identifier : AIDSLINE MED/20003682
- Murakami J; Nagai N; Shigemasa K; Ohama K; Department of Obstetrics and Gynecology, Hiroshima University; School of Medicine, Japan.
- Telomerase is a ribonucleoprotein which has a RNA template to bind and extend telomere ends, so prolonging the life of tumour cells. The aim of this study was to determine whether transcriptase function of telomerase could be inhibited by the reverse transcriptase inhibitors (RTI); azydothymidine (
- Comparative analysis of quantification of viral load in patients infected with hepatitis C virus: quantiplex HCV RNA assay and amplicor monitor assay.
- Rev Esp Enferm Dig. 1999 Aug;91(8):569-82. Unique Identifier : AIDSLINE MED/99423573
- Olaso V; Cordoba J; Lopez B; Arguello L; Molina J; Lainez B; Ortiz V; Pastor M; Prieto M; Berenguer J; Servicio de Medicina Digestiva, Hospital "La Fe", Valencia,; 46009, Espana.
- OBJECTIVE: two standardized techniques, Quantiplex HCV RNA 2.0 (bDNA) and Amplicor Monitor, were evaluated for the quantification of hepatitis C virus (HCV) load. Our objectives were: 1) to determine the relationship between viral load and genotype, and 2) to evaluate viral load in serial serum samples and in patients
- Coping strategies of HIV-positive and HIV-negative female injection drug users: a longitudinal study.
- AIDS Educ Prev. 1999 Oct;11(5):373-88. Unique Identifier : AIDSLINE MED/20022548
- Brook DW; Brook JS; Richter L; Whiteman M; Win PT; Masci JR; Roberto J; Department of Community and Preventive Medicine, Mount Sinai; School of Medicine, New York, NY 10029, USA.
- This study longitudinally examined the psychosocial correlates of coping strategies among 165 HIV positive and 179 HIV negative female injection drug users (IDUs). Participants were interviewed twice using a structured questionnaire, with a 6-month interval between interviews. The questionnaire included psychosocial m
- Improving comprehension and recall of information for an HIV vaccine trial among women at risk for HIV: reading level simplification and inclusion of pictures to illustrate key concepts.
- AIDS Educ Prev. 1999 Oct;11(5):389-99. Unique Identifier : AIDSLINE MED/20022549
- Murphy DA; O'Keefe ZH; Kaufman AH; Health Risk Reduction Projects, Department of Psychiatry,; University of California, Los Angeles 90024, USA.; dmurphy@mednet.ucla.edu
- A simplified version of the prototype HIV vaccine material was developed through (a) reducing reading grade level, (b) restructuring of the organization and categorization of the material, (c) adding pictures designed to emphasize key concepts, and (d) obtaining feedback on the simplified version through focus groups
- A scale to measure attitudes about HIV-antibody testing: development and psychometric validation.
- AIDS Educ Prev. 1999 Oct;11(5):400-13. Unique Identifier : AIDSLINE MED/20022550
- Boshamer CB; Bruce KE; Department of Psychology, University of North Carolina at; Wilmington, 28403, USA.
- Testing for antibodies to HIV is a vital component of many AIDS prevention and intervention programs. To increase the use of HIV antibody testing, it is important to understand more about peoples attitudes about testing so that intervention programs can focus on the specific concerns of the target population. A scale
- Consensus theory model of AIDS/SIDA beliefs in four Latino populations.
- AIDS Educ Prev. 1999 Oct;11(5):414-26. Unique Identifier : AIDSLINE MED/20022551
- Trotter RT 2nd; Weller SC; Baer RD; Pachter LM; Glazer M; Garcia de Alba Garcia JE; Klein RE; Northern Arizona University, Flagstaff, USA.
- To describe Latino beliefs about AIDS (SIDA), Latino adults were sampled at two U.S. sites (Connecticut and Texas) and two international sites ( Mexico and Guatemala ). A 125-item questionnaire covered risk factors, symptoms, treatments, and se
- Aspects of motivation of a volunteer AIDS care team program.
- AIDS Educ Prev. 1999 Oct;11(5):427-35. Unique Identifier : AIDSLINE MED/20022552
- Christensen LA; Reininger BM; Richter DL; McKeown RE; Jones A; Classics of Charleston, Ltd, SC 29401, USA. lachris@innova.net
- The South Carolina AIDS Care Team Program, directed by The Ecumenical AIDS Ministry, a component of the South Carolina Christian Action Council, provides emotional and supportive services to people living with HIV and AIDS. A sample of volunteer care team members participated in five focus groups as part of a process
- African-American volunteers carrying an HIV prevention message: selective communication.
- AIDS Educ Prev. 1999 Oct;11(5):436-49. Unique Identifier : AIDSLINE MED/20022553
- Davison DM; Reeder GD; Teverbaugh K; Department of Social Work, Illinois State University, Normal; 61790, USA. dmdavis@ilstu.edu
- Despite increased resources and funding, the rate of new HIV infections has not been contained within the African American community. Initiatives such as the culturally specific American Red Cross African American HIV/AIDS Program have enlisted thousands of volunteers in the fight against AIDS. This article reports th
- AIDS knowledge, condom attitudes, and risk-taking sexual behavior of substance-abusing juvenile offenders on probation or parole.
- AIDS Educ Prev. 1999 Oct;11(5):450-61. Unique Identifier : AIDSLINE MED/20022554
- Robertson A; Levin ML; Social Science Research Center, Mississippi State University,; Mississippi State 39762, USA. angela.robertson@ssrc.msstate.edu
- AIDS knowledge, condom attitudes, and sexual behavior were examined in a sample of 193 substance-abusing juvenile offenders on probation or parole. The majority of these youths reported being sexually active, and many admitted to early onset of sexual activity as well as unsafe sexual practices. Potential predictors o
- Selenium-dependent glutathione peroxidase modules encoded by RNA viruses.
- Biol Trace Elem Res. 1999 Nov;70(2):97-116. Unique Identifier : AIDSLINE MED/20004178
- Zhang W; Ramanathan CS; Nadimpalli RG; Bhat AA; Cox AG; Taylor EW; Computational Center for Molecular Structure and Design, and; Department of Pharmaceutical and Biomedical Sciences, The; University of Georgia, Athens 30601-2352, USA.
- Glutathione peroxidase (GPx) is the prototypical eukaryotic selenoprotein, with the rare amino acid selenocysteine (Sec) at the enzyme active site, encoded by the UGA codon in RNA. A DNA virus, Molluscum contagiosum, has now been shown to encode a functional selenium-dependent GPx enzyme. Using modifications of conven
- Effect of HIV-1 gp41 peptides on secretion of beta-amyloid precursor protein in human astroglial cell line, T98G.
- J Mol Neurosci. 1999 Apr;12(2):147-56. Unique Identifier : AIDSLINE MED/99454582
- Chong YH; Lee MJ; Department of Microbiology, College of Medicine, Ewha Womans; University, Seoul, Korea.
- To understand the mechanism underlying cognitive deficits in AIDS patients, we examined the influence of gp41 peptides on the expression and the secretion of Alzheimer s amyloid precursor protein (APP) in human astroglial cell line T98G. Western blotting analyses demonstrated that treatment of glial cells with a putat
- Myelodysplastic syndrome in a patient with adult T-cell leukaemia.
- Br J Haematol. 1999 Sep;106(3):702-5. Unique Identifier : AIDSLINE MED/99398085
- Kawabata H; Utsunomiya A; Hanada S; Makino T; Takatsuka Y; Takeuchi S; Suzuki S; Suzumiya J; Ohshima K; Horiike S; Department of Haematology, Imamura Bun-in Hospital, Kagoshima.
- A 53-year-old female who developed myelodysplastic syndrome (MDS) after chemotherapy for adult T-cell leukaemia (ATL) is described. The latent period of therapy-related MDS (t-MDS) from the time of diagnosis of ATL was approximately 35 months. Cytogenetic analysis of the bone marrow cells at the time of diagnosis of t
- Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) DNA sequences are absent in leukapheresis products and ex vivo expanded CD34+ cells from multiple myeloma patients.
- Br J Haematol. 1999 Sep;106(4):1033-6. Unique Identifier : AIDSLINE MED/99451301
- De Greef C; Van De Voorde W; Bakkus M; Corthals J; Heirman C; Schots R; Lacor P; Van Camp B; Van Riet I; Department of Haematology-Immunology, Free University of; Brussels, Belgium.
- Recently it was reported that Kaposi s sarcoma-associated herpesvirus (KSHV/HHV-8) infects bone marrow (BM) dendritic cells (DC) in multiple myeloma (MM) patients and therefore might play a role in MM development. Because of the use of myeloid growth factors like GM-CSF and G-CSF for the mobilization of peripheral blo
- Hepatitis C infection and B-cell non-Hodgkin's lymphoma in British Columbia: a cross-sectional analysis.
- Ann Oncol. 1999 Aug;10(8):961-4. Unique Identifier : AIDSLINE MED/99438575
- Shariff S; Yoshida EM; Gascoyne RD; Le N; Connors JM; Middleton PJ; Shenkier TN; Department of Medicine, University of British Columbia, Canada.
- OBJECTIVES: To determine the prevalence of hepatitis C virus (HCV) infection in patients with B-cell non-Hodgkin s lymphoma (NHL) in British Columbia. DESIGN: A cross-sectional analysis. SETTING: The British Columbia Cancer Agency (BCCA), a Canadian provincial tertiary oncology ref
- The potential importance of HIV-induction of lymphocyte homing to lymph nodes.
- Int Immunol. 1999 Oct;11(10):1591-4. Unique Identifier : AIDSLINE MED/99437880
- Chen JJ; Cloyd MW; Departments of Microbiology-Immunology and Pathology, University; of Texas Medical Branch, Galveston, TX 77555, USA.
- The mechanism by which HIV causes depletion of CD4 lymphocytes remains unknown. Recent studies have demonstrated that HIV binding to resting CD4 lymphocytes causes them to home from the blood into lymph node, and during the homing process, they are induced into apoptosis only to secondary signals through the homing re
- Positive selection of thymocytes induced by gene transfer: MHC class II-mediated selection of CD8 lineage cells.
- Int Immunol. 1999 Oct;11(10):1595-600. Unique Identifier : AIDSLINE MED/99437881
- Rooke R; Waltzinger C; Benoist C; Mathis D; Institut de Genetique et de Biologie Moleculaire et Cellulaire; (CNRS/INSERM/ULP), 67404 Illkirch, CU de Strasbourg, France.
- Recombinant adenovirus vectors are powerful tools for inducing de novo gene expression in vivo. Here we have exploited them to study the specificity of CD4/CD8 lineage commitment during thymocyte positive selection, transferring MHC class II genes directly into thymi of mice deficient in both class I and II molecules.
- Acute cellular rejection of human renal tissue by adoptive transfer of allogeneic human peripheral blood mononuclear cells into chimeric rats: sequential gene expression of cytokines, chemokines and cytolytic effector molecules, and their regulation by CTLA-4-Ig.
- Int Immunol. 1999 Oct;11(10):1673-83. Unique Identifier : AIDSLINE MED/99437889
- Dekel B; Bocher WO; Marcus H; Yussim A; Reisner Y; Department of Immunology, The Weizmann Institute of Science,; Rehovot 76100, Israel.
- T(h)1- and T(h)2-related cytokines (IFN-gamma, IL-2 , IL-4, IL-10), beta-chemokines (RANTES, macrophage inflammatory protein-1beta) and their receptor [chemotatic cytokine receptor (CCR) 5], and the cytolytic effector molecule [Fas ligand (FasL)] play an essential role
- NMR structure of the complex between the zinc finger protein NCp10 of Moloney murine leukemia virus and the single-stranded pentanucleotide d(ACGCC): comparison with HIV-NCp7 complexes.
- Biochemistry. 1999 Oct 5;38(40):12984-94. Unique Identifier : AIDSLINE PDB/1A6B
- Schuler W; Dong C; Wecker K; Roques BP; Departement de Pharmacochimie Moleculaire et Structurale,; INSERM U266-CNRS UMR 8600, UFR des Sciences Pharmaceutiques et; Biologiques, Paris, France.
- The structure of the 56 amino acid nucleocapsid protein NCp10 of retrovirus MoMuLV, which contains a single CX(2)CX(4)HX(4)C-type zinc finger, has been determined previously by NMR. The important role of NCp10 (or NCp7 for HIV-1) in the retroviral life cycle seems mainly related to their preferential binding to single
- Genetic evidence that stress-activated p38 MAP kinase is necessary but not sufficient for UV activation of HIV gene expression.
- Biochemistry. 1999 Oct 5;38(40):13055-62. Unique Identifier : AIDSLINE MED/99459250
- Taher MM; Baumgardner T; Dent P; Valerie K; Department of Radiation Oncology, Massey Cancer Center, Medical; College of Virginia, Virginia Commonwealth University, Richmond; 23298-0058, USA.
- We have examined the role of stress-activated p38 MAP kinase in regulating human immunodeficiency virus (HIV) gene expression in response to ultraviolet light (UV). We found that UV activated p38 in HeLa cells harboring stably integrated copies of an HIVcat plasmid to levels similar to those obtained by hyperosmotic s
- Inhibitors of DNA strand transfer reactions catalyzed by HIV-1 reverse transcriptase.
- Biochemistry. 1999 Oct 5;38(40):13070-6. Unique Identifier : AIDSLINE MED/99459252
- Gabbara S; Davis WR; Hupe L; Hupe D; Peliska JA; Department of Biological Chemistry, University of Michigan; Medical School, Ann Arbor 48109-0606, USA.
- The discovery and characterization of new inhibitors of HIV-1 reverse transcriptase (RT) is an important step toward understanding the mechanism of this multifunctional polymerase. We describe the identification of novel inhibitors of HIV-1 RT-catalyzed reactions utilizing a nucleic acid model system designed to mimic
- Reversible S-nitrosation and inhibition of HIV-1 protease.
- Biochemistry. 1999 Oct 5;38(40):13407-13. Unique Identifier : AIDSLINE MED/99459292
- Sehajpal PK; Basu A; Ogiste JS; Lander HM; Department of Biochemistry, Weill Medical College of Cornell; University, New York 10021, USA.
- Nitric oxide (*NO) is a short-lived free radical with many functions including vasoregulation, synaptic plasticity, and immune modulation and has recently been associated with AIDS pathology. Various pathophysiological conditions, such as viral infection, trigger inducible nitric oxide synthase (iNOS) to synthesize NO
- Drinking perceptions and drinking behaviors among urban black adolescents.
- J Adolesc Health. 1999 Oct;25(4):264-75. Unique Identifier : AIDSLINE MED/99433663
- Strunin L; Social and Behavioral Sciences Department, Boston University; School of Public Health, Massachusetts 02118-2526, USA.
- PURPOSE: To improve understanding of black (African American and Haitian Blacks) adolescents drinking behaviors and sexual patterns that put them at risk for human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) to determine whether specific cultural differences affect beliefs and behaviors about
- An exploratory attempt to distinguish subgroups among crack-abusing African-American women.
- J Addict Dis. 1999;18(3):41-54. Unique Identifier : AIDSLINE MED/99435415
- Cohen ED; Department of Sociology, Pennsylvania State University, Uniontown; 15401, USA. edcl@psu.edu
- Despite the significant emergence of research on female addiction over the last two decades, specific research on African-American women substance abusers, particularly crack cocaine users, is limited. The identification of meaningful subgroups of substance abusing populations, particularly minority women is important
- Poverty, disease progression and employment among people living with HIV/AIDS in Australia.
- AIDS Care. 1999 Aug;11(4):405-14. Unique Identifier : AIDSLINE MED/20003726
- Ezzy D; de Visser R; Bartos M; University of Tasmania, Melbourne, Australia.; Douglas.Ezzy@utas.edu.au
- A national survey of 925 people living with HIV/AIDS (PLWHA) in Australia is used to examine the relationship between disease progression, employment status, poverty and economic hardship. While disease progression has some impact on economic hardship, employment status is found
- Psychological and social correlates of high-risk sexual behaviour among men and women living with HIV/AIDS.
- AIDS Care. 1999 Aug;11(4):415-27. Unique Identifier : AIDSLINE MED/20003727
- Kalichman SC; Center for AIDS Intervention Research (CAIR), Medical College of; Wisconsin 53226, USA.
- Men and women living with HIV/AIDS who experience difficulty maintaining safer sex practices place their sex partners as well as themselves at considerable risk for sexually transmitted infections. Psychological correlates of continued sexual risk behaviours provide important information for intervention development.
- Lack of legal income is strongly associated with an increased risk of AIDS and death in HIV-infected injecting drug users.
- AIDS Care. 1999 Aug;11(4):429-36. Unique Identifier : AIDSLINE MED/20003728
- Piketty C; Castiel P; Giral P; Lhomme JP; Boubilley D; Olievenstein C; Lert F; Kazatchkine MD; Unite d'Immunologie, Hopital Broussais, Universite Pierre et; Marie Curie, Paris, France.; Christophe.piketty@brs.ap-hop-paris.fr
- The aim of the study was to analyze the impact of soci-economic status in addition to other risk factors in the progression of HIV disease in a cohort of injecting drug users (IDUs) with a mean follow-up of two years. Between 1989 and 1992, 124 HIV-infected IDUs were recruited in a primary care outpatient clinic provi
- Geographic proximity, policy and utilization of syringe exchange programmes.
- AIDS Care. 1999 Aug;11(4):437-42. Unique Identifier : AIDSLINE MED/20003729
- Rockwell R; Des Jarlais DC; Friedman SR; Perlis TE; Paone D; National Development and Research Institutes, Inc., New York; 10048, USA.
- The objective of the research was to assess the effects of geographic proximity on the utilization of syringe exchange among injection drug users (IDUs) in New York City. Between 1994 and 1996, 805 IDUs were interviewed with a structured questionnaire. Geographic proximity was defined as living within a ten-minute wal
- AIDS-related information exposure in the mass media and discussion within social networks among married women in Bombay, India.
- AIDS Care. 1999 Aug;11(4):443-6. Unique Identifier : AIDSLINE MED/20003730
- Chatterjee N; School of Public Health, University of Texas Health Science; Center, Houston 77225, USA. sph1974@utsph.sph.uth.tmc.edu
- Married women are at high risk of acquiring HIV infection in India and health education remains the most feasible preventive tool in their context. In a survey conducted among 350 married women in Bombay, it was found that a majority had acquired information about AIDS from the mass
- The parent disclosure interview.
- AIDS Care. 1999 Aug;11(4):447-52. Unique Identifier : AIDSLINE MED/20003731
- Pilowsky DJ; Sohler N; Susser E; Department of Psychiatry, Johns Hopkins University School of; Medicine & Kennedy-Krieger Institute, Baltimore, MD, USA.; pilowsky@kennedykrieger.org
- As the number of HIV-infected women and children in the USA has increased, clinicians and researchers have debated the benefits and risks of disclosure of parental HIV status to children. Disclosure is usually ascertained through interviews of unknown reliability. Given the need to advance knowledge regarding the bene
- Development of the Impact of Weight Loss Scale (IWLS): a psychometric study in a sample of men with HIV/AIDS.
- AIDS Care. 1999 Aug;11(4):453-7. Unique Identifier : AIDSLINE MED/20003732
- Wagner GJ; Rabkin JG; Department of Psychiatry, New York State Psychiatric Institute,; NY 10032, USA. wagnerg@pi.cpmc.columbia.edu
- The purpose of this study was to assess the psychometric properties of the newly developed Impact of Weight Loss Scale (IWLS), a subjective measure of perceived weight loss and related behaviour, body image perception, and affect, as well as the scale s relationship to mental health and nutritional measures in an HIV
- Knowledge, attitudes and practices concerning HIV/AIDS among sex workers in Phnom Penh, Cambodia.
- AIDS Care. 1999 Aug;11(4):459-72. Unique Identifier : AIDSLINE MED/20003733
- Prybylski D; Alto WA; Department of Epidemiology and Preventive Medicine, University of; Maryland School of Medicine, Baltimore 21201-1596, USA.; dprybyls@epi.umaryland.edu
- The human immunodeficiency virus (HIV)/AIDS epidemic is currently spreading faster in Cambodia than anywhere else in Asia. Heterosexual transmission of HIV through prostitution is believed to be catalyzing the epidemic, and sex workers (SWs) are at a very high risk for becoming i
- Contrasting strategies used by young people to ensure condom use: some findings from a qualitative research project.
- AIDS Care. 1999 Aug;11(4):473-9. Unique Identifier : AIDSLINE MED/20003734
- Coleman L; Ingham R; Department of Psychology, University of Southampton, UK.; LMC3@PSY.SOTON.AC.UK
- Interviews conducted among 56 young men and women (aged 16-19) reveal two contrasting strategies used to ensure condom use at first intercourse with a new partner. These are defined as verbal communication based strategies (involving some explicit discussion about contraception before intercourse) and non-verbal commu
- Caring for people with HIV in Zambia: are traditional healers and formal health workers willing to work together?
- AIDS Care. 1999 Aug;11(4):481-91. Unique Identifier : AIDSLINE MED/20003735
- Burnett A; Baggaley R; Ndovi-MacMillan M; Sulwe J; Hang'omba B; Bennett J; Department of General Practice, St. Bartholomew's and the Royal; London Hospital Medical College, UK. a.c.burnett@qmw.ac.uk
- This study of traditional healers and formal health workers determined their knowledge and practices in the field of HIV/AIDS and examined their training needs and attitudes to collaboration, in preparation for planning joint training workshops. Several misconceptions concerning symptoms and transmission of HIV diseas
- Virus-associated lymphomas [see comments]
- Curr Opin Oncol. 1999 Sep;11(5):322-32. Unique Identifier : AIDSLINE MED/99433586
- Cesarman E; Mesri EA; Department of Pathology, Weill Medical College of Cornell; University and The New York Presbyterian Hospital, NY 10021, USA.
- Epstein-Barr virus, Kaposi s sarcoma-associated herpesvirus/human herp