Reversible pulmonary hypertension in POEMS syndrome--another etiology of triggered pulmonary vasculopathy? NLM AIDSLINE Important note: Information in this article was accurate in 2000. The state of the art may have changed since the publication date.

Click here to return to AIDSLINE main menu
DonateNow
Print this Article


Reversible pulmonary hypertension in POEMS syndrome--another etiology of triggered pulmonary vasculopathy?

Can J Cardiol. 2000 Aug;16(8):1007-12. Unique Identifier : AIDSLINE MED/20435621
Paciocco G; Bossone E; Erba H; Rubenfire M; Instituto di Malattie dell'App Respiratorio, Italy.

Abstract: Polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy and skin changes (POEMS) syndrome, a plasma cell dyscrasia associated with pulmonary hypertension, has been treated in the past with anticytokine strategies with a poor outcome. A patient is described who had POEMS syndrome with precapillary pulmonary hypertension and Raynaud's phenomenon, and who responded well to a short course of corticosteroids and long term nifedipine. POEMS syndrome, like anorexigens, cocaine, portal hypertension and human immunodeficiency virus infection, may be another trigger for the pulmonary vascular occlusive process found in primary pulmonary hypertension.

Keywords: JOURNAL ARTICLE REVIEW REVIEW OF REPORTED CASES Adrenal Cortex Hormones/ADMINISTRATION & DOSAGE Case Report Diuretics/ADMINISTRATION & DOSAGE Drug Therapy, Combination Female Human Hypertension, Pulmonary/DIAGNOSIS/DRUG THERAPY/*ETIOLOGY Middle Age Nifedipine/ADMINISTRATION & DOSAGE POEMS Syndrome/*COMPLICATIONS/DIAGNOSIS/DRUG THERAPY Raynaud's Disease/COMPLICATIONS/DIAGNOSIS/DRUG THERAPY Remission Induction Time Factors

KWDjournalarticlereviewreviewofreportedcasesadrenalcortexhormones/administration&dosagecasereportdiuretics/administration&dosagedrugtherapy,combinationfemalehumanhypertension,pulmonary/diagnosis/drugtherapy/KWDetiologymiddleagenifedipine/administration&dosagepoemssyndrome/KWDcomplications/diagnosis/drugtherapyraynaud'sdisease/complications/diagnosis/drugtherapyremissioninductiontimefactors
001230
A00C0918

Copyright © 2000 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Elton John AIDS Foundation, the National Library of Medicine, and donations from users like you. Always watch for outdated information. This article first appeared in 2000. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 2000. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .