Dose-ranging studies. NLM AIDSLINE Important note: Information in this article was accurate in 2000. The state of the art may have changed since the publication date.

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Dose-ranging studies.

Int J Clin Pract Suppl. 1999 Jun;103:8-9. Unique Identifier : AIDSLINE MED/20087916
Manion D; Worldwide Medical Affairs, DuPont Pharmaceuticals Company,; Wilmington, USA.

Abstract: Several studies have been performed to investigate the appropriate dose of efavirenz (SUSTIVA, DMP 266, EFV) for the treatment of HIV infection. When considering the most appropriate dose, virological, pharmacological, clinical and safety data from these studies were examined. Efavirenz 600 mg once daily is the recommended dose of efavirenz for combination therapy in adults. Efavirenz 600 mg once daily adjusted for body size is the appropriate dose for combination therapy in children three years of age or older.

Keywords: JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL Age Factors Anti-HIV Agents/*ADMINISTRATION & DOSAGE/ADVERSE EFFECTS Clinical Trials Dose-Response Relationship, Drug Drug Administration Schedule Drug Therapy, Combination Human HIV Infections/*DRUG THERAPY Oxazines/*ADMINISTRATION & DOSAGE/ADVERSE EFFECTS

KWDjournalarticlereviewreview,tutorialagefactorsanti-hivagents/KWDadministration&dosage/adverseeffectsclinicaltrialsdose-responserelationship,drugdrugadministrationscheduledrugtherapy,combinationhumanhivinfections/KWDdrugtherapyoxazines/KWDadministration&dosage/adverseeffects
000430
A0040879

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