Fatal herpetic hepatitis in adult following short corticotherapy: a case report. NLM AIDSLINE Important note: Information in this article was accurate in 1999. The state of the art may have changed since the publication date.

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Fatal herpetic hepatitis in adult following short corticotherapy: a case report.

Intensive Care Med. 1999 Apr;25(4):415-7. Unique Identifier : AIDSLINE MED/99271947
Seksik P; Gozlan J; Guitton C; Galula G; Maury E; Offenstadt G; Medical Intensive Care Unit, Hopital Saint-Antoine, Assistance; Publique-Hopitaux de Paris, France.


Abstract: Herpes simplex virus hepatitis (HSV hepatitis) is an uncommon and severe complication of HSV type 1 and HSV type 2 infection. HSV hepatitis affects mostly immunocompromised patients. We report the case of a young man without any previous known immunodeficiency who developed fatal HSV hepatitis in the first 8 days of oral corticotherapy given for ulcerative colitis. A prompt diagnosis was possible because HSV was recovered from peripheral blood leukocytes.
Keywords: JOURNAL ARTICLE Acute Disease Adult Anti-Inflammatory Agents, Steroidal/*THERAPEUTIC USE Case Report Colitis, Ulcerative/*DRUG THERAPY Diagnosis, Differential Fatal Outcome Hepatitis, Viral, Human/*DIAGNOSIS Herpes Simplex/*DIAGNOSIS Herpesvirus 1, Human/ISOLATION & PURIF Herpesvirus 2, Human/ISOLATION & PURIF Human Male Prednisone/*THERAPEUTIC USEKWDjournalarticleacutediseaseadultanti-inflammatoryagents,steroidal/KWDtherapeuticusecasereportcolitis,ulcerative/KWDdrugtherapydiagnosis,differentialfataloutcomehepatitis,viral,human/KWDdiagnosisherpessimplex/KWDdiagnosisherpesvirus1,human/isolation&purifherpesvirus2,human/isolation&purifhumanmaleprednisone/KWDtherapeuticuse
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A99A0877

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