Atopic disorders: a default pathway in the absence of infection? NLM AIDSLINE Important note: Information in this article was accurate in 1999. The state of the art may have changed since the publication date.

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Atopic disorders: a default pathway in the absence of infection?

Immunol Today. 1999 Jul;20(7):317-22. Unique Identifier : AIDSLINE MED/99309059
Erb KJ; Zentrum fur Infektionsforschung, Universitat Wurzburg,; Rontgenring 11, 97070 Wurzburg, Germany.; klaus.erb@mai.l.uni-wuerzburg.de

Abstract: Atopic disorders, such as asthma, are increasingly prevalent in the developed world. Recent epidemiological and experimental data suggest that some infectious diseases prevalent in the developing nations can inhibit the development of allergic disorders. Here, Klaus Erb reviews the data and presents a model showing how a steady decline of infectious diseases could account for an increase in atopic disorders.
Keywords: JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL Animal Developing Countries Human Hypersensitivity, Immediate/EPIDEMIOLOGY/*ETIOLOGY/PREVENTION & CONTROL Infection/EPIDEMIOLOGY/*IMMUNOLOGY Models, Biological Support, Non-U.S. Gov't Th1 Cells/IMMUNOLOGY Th2 Cells/IMMUNOLOGYKWDjournalarticlereviewreview,tutorialanimaldevelopingcountrieshumanhypersensitivity,immediate/epidemiology/KWDetiology/prevention&controlinfection/epidemiology/KWDimmunologymodels,biologicalsupport,non-uKWDsKWDgov'tth1cells/immunologyth2cells/immunology
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A99B1140

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