Lower genital tract neoplasia in women with HIV infection. NLM AIDSLINE Important note: Information in this article was accurate in 1999. The state of the art may have changed since the publication date.

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Lower genital tract neoplasia in women with HIV infection.

Oncology (Huntingt). 1998 Dec;12(12):1735-9; discussion 1742, 1745, 1747. Unique Identifier : AIDSLINE MED/99092006
Abercrombie PD; Korn AP; UCSF Department of Obstetrics, Gynecology, and Reproductive; Sciences, San Francisco General Hospital, California, USA.

Abstract: Women who are infected with human immunodeficiency virus (HIV) are at greater risk for the development of lower genital tract neoplasia than are HIV-negative women. Among HIV-positive women, those who are more severely immunosuppressed appear to be at higher risk for cervical intraepithelial neoplasia (CIN), also known as squamous intraepithelial lesions (SILs). Women who are HIV-positive also are more likely than HIV-negative women to have multifocal lower genital tract neoplasia. Cervical cancer is one of the most important acquired immune deficiency syndrome (AIDS)--related malignancies in women. Cancer and intraepithelial neoplasia of the lower genital tract can be persistent, progressive, recurrent, and difficult to treat in HIV-positive women. The most effective method for treating SILs has not been determined. Regular performance of Pap smears in HIV-positive women is of critical importance, as is careful examination of the entire lower genital tract. Also, women with high-grade intraepithelial or cervical cancer should be tested for HIV.
Keywords: JOURNAL ARTICLE REVIEW REVIEW, ACADEMIC Cervical Intraepithelial Neoplasia/*COMPLICATIONS/DIAGNOSIS/ THERAPY/VIROLOGY Cervix Neoplasms/*COMPLICATIONS/DIAGNOSIS/THERAPY/VIROLOGY Female Human HIV Infections/*COMPLICATIONS Papillomavirus, Human Papovaviridae Infections/COMPLICATIONS Tumor Virus Infections/COMPLICATIONSKWDjournalarticlereviewreview,academiccervicalintraepithelialneoplasia/KWDcomplications/diagnosis/therapy/virologycervixneoplasms/KWDcomplications/diagnosis/therapy/virologyfemalehumanhivinfections/KWDcomplicationspapillomavirus,humanpapovaviridaeinfections/complicationstumorvirusinfections/complications
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A9950973

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