Abdominal findings in AIDS-related pulmonary tuberculosis correlated with associated CD4 levels [see comments]

Important note: Information in this article was accurate in 1999. The state of the art may have changed since the publication date.

Abdominal findings in AIDS-related pulmonary tuberculosis correlated with associated CD4 levels [see comments]

Abdom Imaging. 1998 Nov-Dec;23(6):573-7. Unique Identifier : AIDSLINE MED/99119249
Solomon A; Feldman C; Kobilski SA; Department of Diagnostic Radiology, University of Witwatersrand,; Parktown, South Africa.

Abstract: BACKGROUND: To document the abdominal manifestations of tuberculosis (TB) associated with human immunodeficiency virus (HIV) infection and to correlate those findings with CD4 levels. METHODS: Twenty-nine HIV-positive patients with culture-proven Mycobacterium tuberculosis infection were entered into the study. Chest changes were used to separate patients into two groups: those with and those without evidence of previous TB. All patients had standard chest radiographs, routine and high-resolution chest computed tomography (CT), and abdominal ultrasound examinations. Twenty-four patients had abdominal CT scans. RESULTS: The group of patients with no previous radiographic evidence of pulmonary TB had a significantly greater tendency to have manifestations of pulmonary and/or abdominal miliary dissemination. Those patients with radiological evidence of miliary dissemination were significantly more likely to have CD4 counts of less than 300. CONCLUSIONS: Chest and abdominal miliary dissemination of TB in HIV-positive patients is significantly associated with radiologically determined primary onset pulmonary TB. These changes occur predominantly at CD4 counts of less than 300.

Keywords: JOURNAL ARTICLE Adult Aged AIDS-Related Opportunistic Infections/IMMUNOLOGY/*RADIOGRAPHY/ ULTRASONOGRAPHY *CD4 Lymphocyte Count Enzyme-Linked Immunosorbent Assay Female Human Male Middle Age Prospective Studies Statistics, Nonparametric Tomography, X-Ray Computed Tuberculosis, Miliary/IMMUNOLOGY/*RADIOGRAPHY/ULTRASONOGRAPHY Tuberculosis, Pulmonary/IMMUNOLOGY/*RADIOGRAPHY/ULTRASONOGRAPHY Tuberculosis, Splenic/IMMUNOLOGY/*RADIOGRAPHY/ULTRASONOGRAPHY
Comment in: Abdom Imaging 1998 Nov-Dec;23(6):578-9
990530
A9950954

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