[Effects of green tea on growth inhibition and immune regulation of Lewis lung cancer in mice] NLM AIDSLINE Important note: Information in this article was accurate in 1999. The state of the art may have changed since the publication date.

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[Effects of green tea on growth inhibition and immune regulation of Lewis lung cancer in mice]

Chung Hua Yu Fang I Hsueh Tsa Chih. 1997 Nov;31(6):325-9. Unique Identifier : AIDSLINE MED/99080198
Zhu M; Gong Y; Ge G; Institute of Radiation Medicine, Academy of Military Medical; Sciences, Beijing.


Abstract: C57/BL6J mice were inoculated with Lewis lung cancer cells as an experimental model to study the effects of green tea on cancer prevention, inhibition of tumor growth and immune regulation in mice with tumor. Results showed that weight of thymus in C57/BL6J mice and its index declined, proportion of positive CD4 subgroup of T lymphocyte and ratio of CD4+, to CD8+ reduced, baseline chemilumi-nescence decreased in peripheral white blood cells, yeast zymosan stimulated chemiluminescence increased, and number of immunoglobulin M formation cells decreased. It indicated that green tea had obvious inhibition in Lewis lung cancer and protective effects, to various extent, on adverse changes of above indices.
Keywords: JOURNAL ARTICLE Adjuvants, Immunologic/*PHARMACOLOGY Animal Antineoplastic Agents/*PHARMACOLOGY Carcinoma, Lewis Lung/IMMUNOLOGY/*PATHOLOGY Chemiluminescence CD4-CD8 Ratio English Abstract Female In Vitro Leukocytes/IMMUNOLOGY Mice Mice, Inbred C57BL Neoplasm Transplantation Plant Extracts/PHARMACOLOGY Support, Non-U.S. Gov't T-Lymphocytes/*IMMUNOLOGY *TeaKWDjournalarticleadjuvants,immunologic/KWDpharmacologyanimalantineoplasticagents/KWDpharmacologycarcinoma,lewislung/immunology/KWDpathologychemiluminescencecd4-cd8ratioenglishabstractfemaleinvitroleukocytes/immunologymicemice,inbredc57blneoplasmtransplantationplantextracts/pharmacologysupport,non-uKWDsKWDgov'tt-lymphocytes/KWDimmunologyKWDtea
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