Rosai-Dorfman disease (extranodal sinus histiocytosis) in a patient with HIV. NLM AIDSLINE Important note: Information in this article was accurate in 1999. The state of the art may have changed since the publication date.

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Rosai-Dorfman disease (extranodal sinus histiocytosis) in a patient with HIV.

Ear Nose Throat J. 1998 Oct;77(10):855-8. Unique Identifier : AIDSLINE MED/99035944
Perry BP; Gregg CM; Myers S; Lilly S; Mann KP; Prieto V; Division of Otolaryngology-Head and Neck Surgery, Duke University; Medical Center, Durham, North Carolina, USA.

Abstract: Rosai-Dorfman disease, or sinus histiocytosis with massive lymphadenopathy (SHML), is a rare histiocytosis of unknown etiology that most commonly involves the cervical lymph nodes. Extranodal involvement occurs in 30-40% of cases, most often in the head and neck. Characteristic histologic findings include emperiopolesis (engulfment) of lymphocytes and S-100 protein positivity. Treatment of Rosai-Dorfman disease is unnecessary unless the disorder becomes life- or organ-threatening, since the disease will resolve spontaneously in most patients. We present what, to the best of our knowledge, is the first reported case of Rosai-Dorfman disease limited to the skin in a patient infected with human immunodeficiency virus. SHML is described and diagnostic and therapeutic measures are reviewed.
Keywords: JOURNAL ARTICLE Adult Case Report Histiocytosis, Sinus/*COMPLICATIONS/*DIAGNOSIS/SURGERY Human HIV Seropositivity/*COMPLICATIONS Male Nasal Cavity/PATHOLOGY/SURGERYKWDjournalarticleadultcasereporthistiocytosis,sinus/KWDcomplications/KWDdiagnosis/surgeryhumanhivseropositivity/KWDcomplicationsmalenasalcavity/pathology/surgery
990330
A9931077

Copyright © 1999 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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