Evaluation of behavioral and social issues among Thai HIV vaccine trial volunteers. NLM AIDSLINE Important note: Information in this article was accurate in 1999. The state of the art may have changed since the publication date.

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Evaluation of behavioral and social issues among Thai HIV vaccine trial volunteers.

J Acquir Immune Defic Syndr Hum Retrovirol. 1999 Mar 1;20(3):308-14. Unique Identifier : AIDSLINE MED/99174800
Thapinta D; Jenkins RA; Celentano DD; Nitayaphan S; Buapunth P; Triampon A; Morgan PA; Khamboonruang C; Suwanarach C; Yutabootr Y; Ruckphaopunt S; Suwankiti S; Tubtong V; Cheewawat W; McNeil JG; Michael RA; Faculty of Nursing, Research Institute of Health Sciences, Chiang; Mai University, Thailand.

Abstract: Behavioral and social issues were investigated in phase I/II preventive HIV vaccine trial volunteers in Thailand. These included risk behavior, HIV knowledge, distress, and social experiences associated with trial participation. Data were collected at baseline and at 4- and 8-month follow-up visits. Volunteers reported relatively low levels of risk behaviors at baseline and at the follow-up visits. About one fifth reported overtly negative reactions from family or friends. No problems with discrimination in employment, health care, or insurance were reported. Findings add to the evidence suggesting the feasibility of phase I/II prophylactic HIV vaccine trials with low-risk volunteers in Thailand.
Keywords: CLINICAL TRIAL CLINICAL TRIAL, PHASE I CLINICAL TRIAL, PHASE II JOURNAL ARTICLE RANDOMIZED CONTROLLED TRIAL Adult *AIDS Vaccines Double-Blind Method Evaluation Studies Female Follow-Up Studies Human HIV Infections/*PREVENTION & CONTROL Knowledge, Attitudes, Practice Life Style Male Middle Age *Risk-Taking Support, Non-U.S. Gov't Support, U.S. Gov't, Non-P.H.S. Thailand *Vaccines, Synthetic Voluntary Workers/*PSYCHOLOGYKWDclinicaltrialclinicaltrial,phaseiclinicaltrial,phaseiijournalarticlerandomizedcontrolledtrialadultKWDaidsvaccinesdouble-blindmethodevaluationstudiesfemalefollow-upstudieshumanhivinfections/KWDprevention&controlknowledge,attitudes,practicelifestylemalemiddleageKWDrisk-takingsupport,non-uKWDsKWDgov'tsupport,uKWDsKWDgov't,non-pKWDhKWDsKWDthailandKWDvaccines,syntheticvoluntaryworkers/KWDpsychology
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Copyright © 1999 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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