[The effect of chaihu qingxin yin on left cardiac function and T-cell subgroup in peripheral blood in children with viral myocarditis] NLM AIDSLINE Important note: Information in this article was accurate in 1999. The state of the art may have changed since the publication date.

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[The effect of chaihu qingxin yin on left cardiac function and T-cell subgroup in peripheral blood in children with viral myocarditis]

Chung Kuo Chung Hsi I Chieh Ho Tsa Chih. 1997 Feb;17(2):73-5. Unique Identifier : AIDSLINE MED/99029202
Wang XF; Yan WC; Guo ZW; Liaoning College of Traditional Chinese Medicine, Shenyang.

Abstract: OBJECTIVE: To observe the effect of Caihu Qingxin Yin (CHQXY) in treating viral myocarditis. METHODS: CHQXY was used to treat 52 cases of acute viral myocarditis in children, compared with the routine method using energy mixture in 32 patients. RESULTS: (1) The total effective rate of 52 patients using CHQXY was 71.2% which was higher than that of the control group in 32 patients with 53.1%, Ridit analysis, P < 0.01. (2) Functional shortaxial shortening rate (FS) and ejecting fraction (EF) in CHQXY group were superior to those of the control group, P < 0.01. (3) CHQXY might modulate the immune function of T lymphocyte, enabled the CD3 and ratio of CD4/CD8 tended to normalize. CONCLUSION: CHQXY played an important role in the treatment of viral myocarditis with the mechanism of improving the left cardiac function and modulating celluar immune function.
Keywords: CLINICAL TRIAL JOURNAL ARTICLE RANDOMIZED CONTROLLED TRIAL Adolescence Antiviral Agents/PHARMACOLOGY Child Child, Preschool Comparative Study Coxsackievirus Infections/IMMUNOLOGY/*PHYSIOPATHOLOGY Coxsackieviruses B CD4-CD8 Ratio Drugs, Chinese Herbal/*PHARMACOLOGY English Abstract Female Human Male Myocarditis/IMMUNOLOGY/*PHYSIOPATHOLOGY/VIROLOGY T-Lymphocyte Subsets/*DRUG EFFECTS Ventricular Function, Left/*DRUG EFFECTSKWDclinicaltrialjournalarticlerandomizedcontrolledtrialadolescenceantiviralagents/pharmacologychildchild,preschoolcomparativestudycoxsackievirusinfections/immunology/KWDphysiopathologycoxsackievirusesbcd4-cd8ratiodrugs,chineseherbal/KWDpharmacologyenglishabstractfemalehumanmalemyocarditis/immunology/KWDphysiopathology/virologyt-lymphocytesubsets/KWDdrugeffectsventricularfunction,left/KWDdrugeffects
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