Fetal immunization of baboons induces a fetal-specific antibody response. NLM AIDSLINE Important note: Information in this article was accurate in 1999. The state of the art may have changed since the publication date.

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Fetal immunization of baboons induces a fetal-specific antibody response.

Unique Identifier : AIDSLINE MED/99217583
Watts AM; Stanley JR; Shearer MH; Hefty PS; Kennedy RC

Abstract: Neonates face a high risk of infection because of the immaturity of their immune systems. Although the transplacental transfer of maternal antibodies to the fetus may convey improved postnatal immunity, this transfer occurs late in gestation and may fail to prevent in utero infection. Both fetal immunization and in utero exposure to antigen can result in a state of immunologic tolerance in the neonate. Tolerance induction of fetal and
990730
A9971177

Copyright © 1999 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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