Post-exposure prophylaxis for HIV infection in gay and bisexual men. Implications for the future of HIV prevention. NLM AIDSLINE Important note: Information in this article was accurate in 1999. The state of the art may have changed since the publication date.

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Post-exposure prophylaxis for HIV infection in gay and bisexual men. Implications for the future of HIV prevention.

Am J Prev Med. 1998 Aug;15(2):120-7. Unique Identifier : AIDSLINE MED/98379289
Kalichman SC; Center for AIDS Intervention Research, Medical College of; Wisconsin, Milwaukee 53226, USA.


Abstract: OBJECTIVE: To assess the psychological and behavioral characteristics of gay and bisexual men who intend to use antiretroviral post-exposure prophylaxis (PEP) to prevent HIV infection. METHODS: Gay and bisexual men who had not tested HIV seropositive and were not in long-term exclusive sexual relationships (n = 327) completed anonymous surveys consisting of demographic characteristics, gay community acculturation, experience with and attitudes toward PEP, substance use, and sexual behavior in the past 6 months. SETTING: A large annual Gay Pride festival in Atlanta, Georgia. RESULTS: There were 8 (3%) men who had already used PEP and 85 (26%) who planned to use PEP to prevent themselves from becoming HIV infected. Compared to the 242 (74%) men who did not indicate plans to use PEP, those planning to use PEP were younger, less well educated, more likely to have used illicit substances in the past 6 months, and were more likely to have a history of injection drug use. Men intending to use PEP were also more likely to have practiced unprotected anal and oral intercourse as the receptive partner and were more likely to have multiple anal intercourse partners with whom they were receptive. CONCLUSIONS: Gay and bisexual men are generally supportive of the immediate use of PEP and a significant number of men are planning to use PEP, particularly less educated men who use multiple substances and practice the highest-risk sexual behaviors. Concurrent behavioral interventions must, therefore, be considered critical in the advancement of PEP.
Keywords: JOURNAL ARTICLE Adult Anti-HIV Agents/*THERAPEUTIC USE *Bisexuality/PSYCHOLOGY/STATISTICS & NUMER DATA Georgia Health Surveys *Homosexuality, Male/PSYCHOLOGY/STATISTICS & NUMER DATA Human HIV Infections/*PREVENTION & CONTROL Knowledge, Attitudes, Practice Male Motivation Patient Acceptance of Health Care/*STATISTICS & NUMER DATA Risk-Taking Sex Behavior/STATISTICS & NUMER DATA Statistics Substance-Related Disorders Support, U.S. Gov't, P.H.S.KWDjournalarticleadultanti-hivagents/KWDtherapeuticuseKWDbisexuality/psychology/statistics&numerdatageorgiahealthsurveysKWDhomosexuality,male/psychology/statistics&numerdatahumanhivinfections/KWDprevention&controlknowledge,attitudes,practicemalemotivationpatientacceptanceofhealthcare/KWDstatistics&numerdatarisk-takingsexbehavior/statistics&numerdatastatisticssubstance-relateddisorderssupport,uKWDsKWDgov't,pKWDhKWDs
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