[Osteoarticular Mycobacterium xenopi infection] NLM AIDSLINE Important note: Information in this article was accurate in 1999. The state of the art may have changed since the publication date.

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[Osteoarticular Mycobacterium xenopi infection]

Presse Med. 1998 May 2-9;27(17):800-3. Unique Identifier : AIDSLINE MED/98440997
Ollagnier E; Fresard A; Guglielminotti C; Carricajo A; Mosnier JF; Alexandre C; Lucht F; Service de Rhumatologie, Hopital de Bellevue, CHU de; Saint-Etienne.

Abstract: BACKGROUND: Mycobacterium xenopi is a potential pathogen for man and can cause bone and joint infections, particularly spondylodiscitis. Most cases of infection occur in fragilized patients and are found more and more often in AIDS patients. CASE REPORT: A 41-year-old HIV+ woman developed cervical spondylodiscitis due to Mycobacterium xenopi infection. The strain was isolated from a discovertebral biopsy and was resistant to several antibiotics. Outcome was unfavorable. DISCUSSION: Most of the cases reported to date have involved spondylodiscitis of the thoracic or lumbar spine. To our knowledge, this is the first report of cervical spondylodiscitis dut to Mycobacterium xenopi in an HIV+ patient. Antibiotic combinations using fluoroquinolones and new macrolides are usually prescribed. Such protocols may provide cure of these opportunistic infections in immunodeficient patients.
Keywords: JOURNAL ARTICLE Adult Antibiotics, Antitubercular/THERAPEUTIC USE AIDS-Related Opportunistic Infections/*DIAGNOSIS Biopsy Case Report Cervical Vertebrae/*MICROBIOLOGY Discitis/*MICROBIOLOGY English Abstract Fatal Outcome Female Human *HIV Seropositivity *Mycobacterium xenopi/DRUG EFFECTS Mycobacterium Infections, Atypical/*DIAGNOSIS Tuberculosis, Multidrug-Resistant/DRUG THERAPY Tuberculosis, Spinal/*MICROBIOLOGYKWDjournalarticleadultantibiotics,antitubercular/therapeuticuseaids-relatedopportunisticinfections/KWDdiagnosisbiopsycasereportcervicalvertebrae/KWDmicrobiologydiscitis/KWDmicrobiologyenglishabstractfataloutcomefemalehumanKWDhivseropositivityKWDmycobacteriumxenopi/drugeffectsmycobacteriuminfections,atypical/KWDdiagnosistuberculosis,multidrug-resistant/drugtherapytuberculosis,spinal/KWDmicrobiology
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