HIV-2 and T cell recognition. NLM AIDSLINE Important note: Information in this article was accurate in 1999. The state of the art may have changed since the publication date.

Click here to return to AIDSLINE main menu
DonateNow
Print this Article


HIV-2 and T cell recognition.

Curr Opin Immunol. 1998 Aug;10(4):382-7. Unique Identifier : AIDSLINE MED/98390152
Whittle HC; Ariyoshi K; Rowland-Jones S; MRC Laboratories, The Gambia, West Africa. whittle@commit.gm

Abstract: HIV-2 is less pathogenic and less transmissible than HIV-1. Recent research in relation to deletions in the HIV nef gene and to immune cross-reactions between infections by HIV-2, HIV-1 and simian immunodeficiency virus suggests that T cell recognition and the control of viral replication may be more efficient in HIV-2 infection than in HIV-1 infection. These insights may be crucial to the design of effective vaccines.
Keywords: JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL Animal *AIDS Vaccines Human HIV Infections/EPIDEMIOLOGY/*VIROLOGY HIV-1/IMMUNOLOGY HIV-2/GENETICS/*IMMUNOLOGY T-Lymphocytes/*IMMUNOLOGY Vaccines, AttenuatedKWDjournalarticlereviewreview,tutorialanimalKWDaidsvaccineshumanhivinfections/epidemiology/KWDvirologyhiv-1/immunologyhiv-2/genetics/KWDimmunologyt-lymphocytes/KWDimmunologyvaccines,attenuated
990228
A9920981

Copyright © 1999 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Bristol-Myers Squibb Company, Elton John AIDS Foundation, Gill Foundation, the National Library of Medicine, Quest Diagnostics, Roche and Trimeris, and donations from users like you. Always watch for outdated information. This article first appeared in 1999. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1999. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .