[Cytogenic characteristics and virogenic status of lymphoid cells from malignant baboon lymphomas]

Important note: Information in this article was accurate in 1999. The state of the art may have changed since the publication date.

[Cytogenic characteristics and virogenic status of lymphoid cells from malignant baboon lymphomas]

Vestn Ross Akad Med Nauk. 1999;(7):49-53. Unique Identifier : AIDSLINE MED/99397217
Agrba VZ; Medvedeva NM; Iakovleva LA; Chikobava MG; Araviashvili DE; Timanovskaia VV; Lapin BA

Abstract: Four lymphoid cell cultures obtained from Papio hamadryads with malignant lymphomas were studied. The cultured cells produced two lymphotropic EBV-like herpes virus of Papio (HVP) and T-lymphotropic monkey retrovirus STLV-1 (HTLV-1 family) or HVP alone. More than 100 subcultured cell lines were shown to remain mixed B- and T-cellular, the levels of T cells of different subpopulations were 15-50%. Cytogenetic investigations showed that one of the 4 cultures was tumorogenic and the others were derived from the normal cells of monkeys with malignant lymphomas. It is suggested that the presence of a cultural virus (viruses) may affect the karyotypes of cells.

Keywords: JOURNAL ARTICLE limfoidnykh kletok iz zlokachestvennykh limfom pavianov. Animal B-Lymphocytes/PATHOLOGY/*VIROLOGY Comparative Study English Abstract Herpesviridae Infections/PATHOLOGY/VETERINARY/VIROLOGY Herpesvirus 1, Cercopithecine/*ISOLATION & PURIF HTLV-I Infections/PATHOLOGY/VETERINARY/VIROLOGY Lymphoma/*PATHOLOGY/VETERINARY/VIROLOGY *Papio STLV/*ISOLATION & PURIF T-Lymphocytes/PATHOLOGY/*VIROLOGY Tumor Cells, Cultured
991230
A99C1029

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Bristol-Myers Squibb Company, Elton John AIDS Foundation, Gill Foundation, the National Library of Medicine, Quest Diagnostics, Roche and Trimeris, and donations from users like you. Always watch for outdated information. This article first appeared in 1999. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1999. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .