Prevalence of sinonasal symptoms in patients with HIV infection.

Important note: Information in this article was accurate in 1999. The state of the art may have changed since the publication date.

Prevalence of sinonasal symptoms in patients with HIV infection.

Am J Rhinol. 1999 May-Jun;13(3):203-8. Unique Identifier : AIDSLINE MED/99320536
Porter JP; Patel AA; Dewey CM; Stewart MG; Bobby R. Alford Department of Otorhinolaryngology and; Communicative Sciences, Baylor College of Medicine, Houston,; Texas 77030, USA.

Abstract: Infection with the human immunodeficiency virus (HIV) is increasing in prevalence, and disease patterns are changing as patient survival lengthens. The purpose of this cross-sectional epidemiological study was to assess the prevalence and severity of self-reported symptoms of otolaryngologic disease in a group of patients attending a general HIV outpatient clinic (n = 203), and to compare the prevalence of self-reported symptoms with a sample of patients without HIV infection (n = 100). Of the HIV-infected patients, 65% of patients had AIDS, 35% were HIV-positive, and the median CD4 count was 135. Although only 11% of patients had seen an otolaryngologist in the prior 6 months, the majority of patients (66%) reported the presence of sinonasal disease during that time. Allergic rhinitis (80%) and sinusitis (54%) were the most commonly reported sinonasal symptoms, and 44% regularly used nasal or sinus medications. Sinonasal disease severity was significantly higher than the self-reported severity of mouth/throat disease (p = 0.01), ear disease (p = 0.03), and neck/salivary disease (p = 0.01). Although patients' self-reported overall health status was associated (p = 0.02) with CD4 count, the severity of sinonasal symptoms was not associated (p = 0.93) with CD4 count. Similarly, sinonasal symptom severity did not differ between HIV-positive and AIDS patients (p = 0.45). In other words, sinonasal disease severity did not improve as general health status improved.

Keywords: CLINICAL TRIAL JOURNAL ARTICLE Acquired Immunodeficiency Syndrome/*COMPLICATIONS/EPIDEMIOLOGY/ IMMUNOLOGY Adolescence Adult Cross-Sectional Studies CD4 Lymphocyte Count Female Human HIV Seropositivity/*COMPLICATIONS/EPIDEMIOLOGY/IMMUNOLOGY Immunocompromised Host Male Middle Age Nasal Obstruction/*COMPLICATIONS/EPIDEMIOLOGY Prevalence Questionnaires Sinusitis/*COMPLICATIONS/EPIDEMIOLOGY Statistics, Nonparametric Texas/EPIDEMIOLOGY
991230
A99C1000

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