Cryptosporidium, enterocytozoon, and cyclospora infections in pediatric and adult patients with diarrhea in Tanzania.

Important note: Information in this article was accurate in 1999. The state of the art may have changed since the publication date.

Cryptosporidium, enterocytozoon, and cyclospora infections in pediatric and adult patients with diarrhea in Tanzania.

Clin Infect Dis. 1999 Feb;28(2):314-21. Unique Identifier : AIDSLINE MED/99162013
Cegielski JP; Ortega YR; McKee S; Madden JF; Gaido L; Schwartz DA; Manji K; Jorgensen AF; Miller SE; Pulipaka UP; Msengi AE; Mwakyusa DH; Sterling CR; Reller LB; Duke University Medical Center, Durham, North Carolina, USA.; gzc2@cdc.gov

Abstract: Cryptosporidiosis, microsporidiosis, and cyclosporiasis were studied in four groups of Tanzanian inpatients: adults with AIDS-associated diarrhea, children with chronic diarrhea (of whom 23 of 59 were positive [+] for human immunodeficiency virus [HIV]), children with acute diarrhea (of whom 15 of 55 were HIV+), and HIV control children without diarrhea. Cryptosporidium was identified in specimens from 6/86 adults, 5/59 children with chronic diarrhea (3/5, HIV+), 7/55 children with acute diarrhea (0/7, HIV+), and 0/20 control children. Among children with acute diarrhea, 7/7 with cryptosporidiosis were malnourished, compared with 10/48 without cryptosporidiosis (P < .01). Enterocytozoon was identified in specimens from 3/86 adults, 2/59 children with chronic diarrhea (1 HIV+), 0/55 children with acute diarrhea, and 4/20 control children. All four controls were underweight (P < .01). Cyclospora was identified in specimens from one adult and one child with acute diarrhea (HIV-). Thus, Cryptosporidium was the most frequent and Cyclospora the least frequent pathogen identified. Cryptosporidium and Enterocytozoon were associated with malnutrition. Asymptomatic fecal shedding of Enterocytozoon in otherwise healthy, HIV children has not been described previously.

Keywords: JOURNAL ARTICLE Acute Disease Adolescence Adult Animal Child Child, Preschool Chronic Disease Coccidiosis/*EPIDEMIOLOGY Cryptosporidiosis/*EPIDEMIOLOGY Diarrhea/*EPIDEMIOLOGY Human Infant Microspora Infections/*EPIDEMIOLOGY Middle Age Support, Non-U.S. Gov't Tanzania/EPIDEMIOLOGY
990830
A9980945

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