Encephalitozoon intestinale infection in an AIDS patient--a case report.

Important note: Information in this article was accurate in 1999. The state of the art may have changed since the publication date.

Encephalitozoon intestinale infection in an AIDS patient--a case report.

Cent Eur J Public Health. 1999 Feb;7(1):43-6. Unique Identifier : AIDSLINE MED/99183768
Kucerova-Pospisilova Z; Stankova M; Ditrich O; Institute of Parasitology, Academy of Sciences of the Czech; Republic, Ceske Budejovice, Czech Republic.

Abstract: The first case of one of the most frequent intestinal microsporidians, Encephalitozoon intestinale, is reported from an AIDS patient in the Czech Republic. The patient experienced diarrhoea and was found to have microsporidia spores in stool. Species determination by electron microscopy confirmed the diagnosis of the microsporidian, E. intestinale. The CD4-count at the time of the diagnosis was 73 cells/mm3, IRI = 0.21. Only after symptomatic therapy and rehydration the patient stopped the complaining, and although he refused an antimicrosporidial therapy, the CD4-count one month later increased to 200 cells/mm3 and patient didn't suffered from diarrhoea. Six months after the first finding of microsporidia, the patient was admitted to the hospital care for progressive encephalopathy and developing wasting syndrome again with the intermittent diarrhoea. The patient was treated with albendazole at that time. Nevertheless, after 14 days of albendazole therapy, he still remained positive for E. intestinale spores in the stool (urine specimens remained negative for all the time). The patient died after a two-month hospitalisation and the apparent cause of death was purulent bronchopneumonia, wasting syndrome with microsporidiosis, and HIV encephalopathy. Generalised mycobacteriosis (MAC) was also found from the autopsy material.

Keywords: JOURNAL ARTICLE Albendazole/THERAPEUTIC USE Antiprotozoal Agents/THERAPEUTIC USE Autopsy AIDS-Related Opportunistic Infections/*DIAGNOSIS/DRUG THERAPY Case Report Cause of Death Czech Republic Encephalitozoonosis/*DIAGNOSIS/DRUG THERAPY Human Intestinal Diseases, Parasitic/*DIAGNOSIS/DRUG THERAPY Male Microscopy, Electron Middle Age
990830
A9980929

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