Nitrite inhalants: history, epidemiology, and possible links to AIDS. NLM AIDSLINE Important note: Information in this article was accurate in 1998. The state of the art may have changed since the publication date.

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Nitrite inhalants: history, epidemiology, and possible links to AIDS.

Environ Health Perspect. 1994 Oct;102(10):858-61. Unique Identifier : AIDSLINE MED/98409945
Haverkos HW; Kopstein AN; Wilson H; Drotman P; National Institute of Drug Abuse, Rockville, MD 20857, USA.

Abstract: Nitrite inhalants have been commonly abused substances in the United States. Nitrite inhalants and AIDS was a popular topic in the early 1980s, when the cause of AIDS was not known. With the discovery of HIV, concern about nitrite use in the USA waned. However, nitrite inhalant use is associated with behavioral relapse and HIV transmission among gay men, with decreased lymphocyte counts and natural killer cell activity in a few laboratory studies, and it remains a candidate cofactor in the pathogenesis of AIDS-related Kaposi's sarcoma. Discouraging nitrite use continues to be a worthwhile public health goal.
Keywords: JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL Acquired Immunodeficiency Syndrome/EPIDEMIOLOGY/*ETIOLOGY/ TRANSMISSION Human Male Nitrites/ADMINISTRATION & DOSAGE/*ADVERSE EFFECTS/THERAPEUTIC USE Risk Factors Sarcoma, Kaposi/EPIDEMIOLOGY/*ETIOLOGY Substance-Related Disorders/*COMPLICATIONS United States/EPIDEMIOLOGYKWDjournalarticlereviewreview,tutorialacquiredimmunodeficiencysyndrome/epidemiology/KWDetiology/transmissionhumanmalenitrites/administration&dosage/KWDadverseeffects/therapeuticuseriskfactorssarcoma,kaposi/epidemiology/KWDetiologysubstance-relateddisorders/KWDcomplicationsunitedstates/epidemiology
981230
M98C7410

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