Intracerebral haemorrhage in AIDS. NLM AIDSLINE Important note: Information in this article was accurate in 1998. The state of the art may have changed since the publication date.

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Intracerebral haemorrhage in AIDS.

Cerebrovasc Dis. 1998 Jul-Aug;8(4):222-7. Unique Identifier : AIDSLINE MED/98348687
Roquer J; Palomeras E; Knobel H; Pou A; Servei de Neurologia, Hospital del Mar, Autonomous University of; Barcelona, Spain. 35826@imas.imim.es

Abstract: We report 8 patients with the acquired immunodeficiency syndrome (AIDS) and intracerebral haemorrhage. There were 7 men and 1 woman (mean age 37.2 years) with a mean CD4 count of 81.2/mm3. Alcohol abuse was recorded in 7 patients, intravenous drug use in 4, homosexual activity in 2, thrombocytopaenia in 1 and severe hypertension in 1. There were 5 lobar and 3 deep haemorrhages. Potential aetiologies of intracerebral haemorrhage included cerebral toxoplasmosis (n = 2), thrombocytopenia (n = 2), hypertension (n = 1) and cerebral tuberculosis (n = 1). Data of these patients were compared with those of 30 AIDS inpatients without brain haemorrhage matched by age and sex and no statistically significant differences in risk factors for AIDS except for alcohol abuse (> 80 g/day) (p = 0.045) were found. Causes of brain haemorrhage in AIDS patients are heterogeneous. The relationship between both conditions may be explained by the effect of several predisposing factors to stroke in association with AIDS-related complications. Intracerebral haemorrhage is a late and serious complication of AIDS (mortality 62.5%). The frequency of intracerebral haemorrhage in AIDS (1.0%) is higher than that expected in a general population of young adults.
Keywords: JOURNAL ARTICLE Acquired Immunodeficiency Syndrome/*COMPLICATIONS Adult Cerebral Hemorrhage/*ETIOLOGY/RADIOGRAPHY Female Human Male Middle Age Prognosis Retrospective Studies Tomography, X-Ray ComputedKWDjournalarticleacquiredimmunodeficiencysyndrome/KWDcomplicationsadultcerebralhemorrhage/KWDetiology/radiographyfemalehumanmalemiddleageprognosisretrospectivestudiestomography,x-raycomputed
981230
M98C6642

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