An indolent penile herpetic ulcer in a patient with previously undiagnosed human immunodeficiency virus infection. NLM AIDSLINE Important note: Information in this article was accurate in 1998. The state of the art may have changed since the publication date.

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An indolent penile herpetic ulcer in a patient with previously undiagnosed human immunodeficiency virus infection.

Br J Dermatol. 1998 Feb;138(2):334-6. Unique Identifier : AIDSLINE MED/98265596
Tayal SC; Pattman RS; Mclelland J; Sviland L; Snow MH; Department of Genito-Urinary Medicine, Newcastle General Hospital,; Newcastle Upon Tyne, U.K.

Abstract: We report a case of an atypical penile herpetic ulcer in a man with previously undiagnosed human immunodeficiency virus (HIV) infection. Swabs of the lesion were negative for herpes simplex virus (HSV) by culture and electron microscopy. However, histopathology of biopsy material showed characteristic herpetic multinucleate giant cells. Immunochemistry using polyclonal antibodies was positive for HSV1 and HSV2. The lesion completely resolved after treatment with aciclovir and the patient subsequently tested positively for HIV antibodies.
Keywords: *Herpes Genitalis/COMPLICATIONS *Herpesvirus 1, Human *Herpesvirus 2, Human *HIV Infections/COMPLICATIONS *Penile Diseases/VIROLOGY *Ulcer/VIROLOGYKWDherpesgenitalis/complicationsKWDherpesvirus1,humanKWDherpesvirus2,humanKWDhivinfections/complicationsKWDpenilediseases/virologyKWDulcer/virology
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