New AIDS study suppresses T cells to stop viral growth. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.

Important note: Information in this article was accurate in 1997. The state of the art may have changed since the publication date.

New AIDS study suppresses T cells to stop viral growth. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.

AIDS Alert. 1997 Jul;12(7):77-8. Unique Identifier : AIDSLINE MED/97702685

Abstract: A controversial new study of the experimental drug BCX-34 is underway by Biocryst Pharmaceuticals. The drug suppresses T cells, a radically different approach; however, the drug is highly reversible. T cell counts return to pretreatment levels within two weeks after the drug is discontinued. The drug is already in Phase III studies for cutaneous T cell lymphoma and for psoriasis, and has proven safe for both those conditions. BCX-34 is expected to reduce the speed with which the virus develops resistance.

Keywords: *CD4-Positive T-Lymphocytes/DRUG EFFECTS *CD4-Positive T-Lymphocytes/IMMUNOLOGY *HIV Infections/DRUG THERAPY *Immunosuppressive Agents/THERAPEUTIC USE
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