1997
- Synthesis, antiviral and antiproliferative activity of a new class of 5-(alkyl or arylthio)-6-vinyl uracils.
- Anticancer Drug Des. 1996 Dec;11(8):597-609. Unique Identifier : AIDSLINE MED/97175088
- Baraldi PG; Cacciari B; Romagnoli R; Spalluto G; Garuti L; Roberti M; Pani A; Perra G; Scintu F; Pinna N; Musiu C; La Colla P
- Uracil derivatives bearing substituted or unsubstituted vinyl groups at position C6 and alkyl- or arylthio groups at position C5 were synthesized and tested in vitro for antiviral and antiproliferative activity. None of the compounds were active against HIV-1. However, some of them inhibited the proliferation of leuke
- Naltrexone prevents ethanol-induced changes in rat thymus.
- Alcohol. 1996 Nov-Dec;13(6):533-7. Unique Identifier : AIDSLINE MED/97107198
- Budec M; Leposavic G; Karapetrovic B; Kosec D; Institute for Medical Research, Beograd, Yugoslavia.
- Ethanol is known to suppress the immune response, but the underlying mechanism accounting for the immunosuppression is not clearly elucidated yet. The purpose of this study was to investigate the effect of a single dose of ethanol on relative proportion of the four major rat thymocyte subsets and possible mechanism of
- Shedding of HIV-1 in the genital tract [editorial]
- AIDS. 1996 Oct;10(12):1305-15. Unique Identifier : AIDSLINE MED/97057719
- Mostad SB; Kreiss JK
- RANTES, MIP-1 alpha and MIP-1 beta are not involved in the inhibition of HIV-1SF33 replication mediated by CD8+ T-cell clones.
- AIDS. 1996 Oct;10(12):1317-21. Unique Identifier : AIDSLINE MED/97057720
- Paliard X; Lee AY; Walker CM; Chiron Corporation, Virology and Vaccine Development, Emeryville, CA; 94608, USA.
- OBJECTIVE: To determine whether CD8+ cells inhibit HIV replication in vitro through the chemokines RANTES, macrophage inflammatory protein (MIP)-1 alpha and MIP-1 beta. DESIGN AND METHODS: CD8+ T-cell clones were screened for their ability to inhibit HIV-1SF33 replication in CD4+ cells using p24 antigen and HIV RNA le
- Functional interaction between the HIV-1 Tat transactivator and the inhibitory domain of the Oct-2 cellular transcription factor.
- AIDS. 1996 Oct;10(12):1323-9. Unique Identifier : AIDSLINE MED/97057721
- Liu YZ; Lania L; Latchman DS; Department of Molecular Pathology, University College London Medical; School, UK.
- OBJECTIVES: To examine the interaction of the HIV Tat protein and the inhibitory domain of the cellular transcription factor Oct-2. DESIGN: HIV reporter plasmids were co-transfected with expression vectors encoding wild-type and mutant Tat proteins and vectors encoding the inhibitory domain either alone or linked to a
- Chimeric viruses between SIVmac and various HIV-1 isolates have biological properties that are similar to those of the parental HIV-1.
- AIDS. 1996 Oct;10(12):1331-7. Unique Identifier : AIDSLINE MED/97057722
- Kuwata T; Shioda T; Igarashi T; Ido E; Ibuki K; Enose Y; Stahl-Hennig C; Hunsmann G; Miura T; Hayami M; Institute for Virus Research, Kyoto University, Japan.
- OBJECTIVE: To examine the biological properties of HIV-1/SIVmac chimeric viruses from HIV-1 isolates that have different replication rates, cell tropisms and cytopathicities. DESIGN AND METHODS: Four chimeric viruses with gag, pol, vif, vpx, nef and long terminal repeats of SIVmax and vpr, tat, rev, vpu and env of var
- Buspirone, a serotonin receptor agonist, increases CD4 T-cell counts and modulates the immune system in HIV-seropositive subjects.
- AIDS. 1996 Oct;10(12):1339-47. Unique Identifier : AIDSLINE MED/97057723
- Hofmann B; Afzelius P; Iversen J; Kronborg G; Aabech P; Benfield T; Dybkjaer E; Nielsen JO; Department of Clinical Immunology, Copenhagen University Hospitals,; Hvidovre, Denmark.
- OBJECTIVE: We have previously shown that drugs that decrease intracellular cAMP levels increase/restore the proliferative and cytotoxic capacity of T cells from HIV-seropositive subjects in vitro. Buspirone, a serotonin receptor agonist, indirectly decreases intracellular cAMP levels in T cells and has the same increa
- Inflammatory cytokines and inhibitors in HIV infection: correlation between interleukin-1 receptor antagonist and weight loss.
- AIDS. 1996 Oct;10(12):1349-56. Unique Identifier : AIDSLINE MED/97057724
- Rimaniol AC; Zylberberg H; Zavala F; Viard JP; Institut National de la Sante et de la Recherche Medicale INSERM) U25,; Necker Hospital, Paris, France.
- OBJECTIVE: To determine serum levels of the interleukin-1 receptor antagonist (IL-1Ra), together with cytokines, other cytokine inhibitors and markers of immune activation in HIV-infected patients. METHODS: Sixty-one HIV-patients were classified into Center for Disease Control and Prevention (CDC) groups A (n = 14), B
- Pilot study of the efficacy of atevirdine in the treatment of AIDS dementia complex.
- AIDS. 1996 Oct;10(12):1357-60. Unique Identifier : AIDSLINE MED/97057725
- Brew BJ; Dunbar N; Druett JA; Freund J; Ward P; National Centre in HIV Epidemiology and Clinical Research,; Darlinghurst, Sydney, Australia.
- OBJECTIVES: To determine the efficacy of the non-nucleoside reverse transcriptase inhibitor atevirdine in the treatment of AIDS dementia complex (ADC). DESIGN: Open label pilot study. METHODS: Ten patients with ADC (stage 1 or 2) who were intolerant to zidovudine or dideoxyinosine,
- The effect of zidovudine dose on the formation of intracellular phosphorylated metabolites.
- AIDS. 1996 Oct;10(12):1361-7. Unique Identifier : AIDSLINE MED/97057726
- Barry MG; Khoo SH; Veal GJ; Hoggard PG; Gibbons SE; Wilkins EG; Williams O; Breckenridge AM; Back DJ; Department of Pharmacology and Therapeutics, University of Liverpool,; UK.
- OBJECTIVES: Zidovudine (ZDV) requires intracellular phosphorylation to ZDV triphosphate (ZDV-TP) prior to the inhibition of HIV replication. The effect of ZDV dose on the formation of intracellular phosphorylated metabolites may help define the optimum daily dose of ZDV, which is still unknown. DESIGN AND METHODS: The
- Itraconazole cyclodextrin solution for fluconazole-refractory oropharyngeal candidiasis in AIDS: correlation of clinical response with in vitro susceptibility.
- AIDS. 1996 Oct;10(12):1369-76. Unique Identifier : AIDSLINE MED/97057727
- Phillips P; Zemcov J; Mahmood W; Montaner JS; Craib K; Clarke AM; AIDS Research Program, St Paul's Hospital, Vancouver, Canada.
- OBJECTIVE: To evaluate the efficacy of itraconazole cyclodextrin solution in fluconazole-refractory oropharyngeal candidiasis OPC), and to correlate clinical outcome with in vitro susceptibility and serum azole levels. DESIGN: A prospective, open-label, intervention study. SETTING: A university hospital, which serves
- Energy balance in asymptomatic HIV infection.
- AIDS. 1996 Oct;10(12):1377-84. Unique Identifier : AIDSLINE MED/97057728
- Sharpstone DR; Murray CP; Ross HM; Hancock MR; Phelan MS; Crane RC; Menzies IS; Reaveley DA; Lepri AC; Nelson MR; Gazzard BG; Department of HIV/Genito-Urinary Medicine, Chelsea and Westminster; Hospital, London, UK.
- OBJECTIVES: Body weight is regulated by the balance between energy intake and energy expenditure, but the influence of HIV infection on energy balance has not been fully examined. The main objectives of this study were (1) to assess the effect of HIV on energy balance, (2) to examine the relationship of parameters of
- Intestinal inflammation, ileal structure and function in HIV.
- AIDS. 1996 Oct;10(12):1385-91. Unique Identifier : AIDSLINE MED/97057729
- Bjarnason I; Sharpstone DR; Francis N; Marker A; Taylor C; Barrett M; Macpherson A; Baldwin C; Menzies IS; Crane RC; Smith T; Pozniak A; Gazzard BG; Department of Clinical Biochemistry, King's College School of Medicine; and Dentistry, London, UK.
- OBJECTIVES: This study examines small intestinal absorption-permeability, intestinal inflammation and ileal structure and function in HIV-positive male homosexuals. METHODS: Thirty HIV-seropositive male homosexuals at various stages of disease underwent intestinal absorption permeability and 111indium leukocyte studie
- Toxoplasmic encephalitis in HIV-infected persons: risk factors and trends. The Adult/Adolescent Spectrum of Disease Group.
- AIDS. 1996 Oct;10(12):1393-9. Unique Identifier : AIDSLINE MED/97057730
- Jones JL; Hanson DL; Chu SY; Ciesielski CA; Kaplan JE; Ward JW; Navin TR; Division of HIV/AIDS Prevention, Centers for Disease Control and; Prevention, Atlanta, Georgia 30333, USA.
- OBJECTIVE: To evaluate the incidence of and risk factors for toxoplasmic encephalitis among HIV-infected persons. DESIGN: Medical facility-based prospective medical record reviews of consecutive patients. METHODS: We analysed data collected from January 1990 through August 1995 in more than 90 inpatient and outpatient
- Declining incidence and later occurrence of Kaposi's sarcoma among persons with AIDS in Australia: the Australian AIDS cohort.
- AIDS. 1996 Oct;10(12):1401-6. Unique Identifier : AIDSLINE MED/97057731
- Dore GJ; Li Y; Grulich AE; Hoy JF; Mallal SA; Mijch AM; French MA; Cooper DA; Kaldor JM; National Centre in HIV Epidemiology and Clinical Research, University; of New South Wales, Sydney, Australia.
- OBJECTIVE: To explore trends in cumulative incidence of Kaposi s sarcoma (KS) and the level of immunodeficiency at KS diagnosis among people with AIDS in Australia . SETTING: Three hospital-based HIV units. STUDY POPULATION: Retrospective cohort of 2580 people diagnosed with AIDS
- Incidence and spectrum of severe medical complications among hospitalized HIV-seronegative and HIV-seropositive narcotic drug users [see comments]
- AIDS. 1996 Oct;10(12):1407-14. Unique Identifier : AIDSLINE MED/97057732
- Scheidegger C; Zimmerli W; Department of Internal Medicine, University Hospital of Basel,; Switzerland.
- OBJECTIVE: To examine differences in the incidence and spectrum of diseases, as well as duration of inpatient stay, between HIV-seronegative and HIV-seropositive narcotic drug, users (NDU). DESIGN: Retrospective analysis of 9 years of experience. Data collection by chart review using preset criteria for diagnoses. Est
- Changes in male sexual behaviour in response to the AIDS epidemic: evidence from a cohort study in urban Tanzania.
- AIDS. 1996 Oct;10(12):1415-20. Unique Identifier : AIDSLINE MED/97057733
- Ng'weshemi JZ; Boerma JT; Pool R; Barongo L; Senkoro K; Maswe M; Isingo R; Schapink D; Nnko S; Borgdorff MW; Tanzania-Netherlands Project to Support AIDS Control in Mwanza Region; (TANESA), Mwanza, Tanzania.
- OBJECTIVE: To examine changes in sexual behaviour among men in urban Tanzania . DESIGN: An observational cohort study among factory workers during 1991-1994. METHODS: Data from five follow-up visits with structured questionnaire-guided interviews and biomedical data were analysed
- Quality of life in HIV disease as measured by the McGill quality of life questionnaire.
- AIDS. 1996 Oct;10(12):1421-7. Unique Identifier : AIDSLINE MED/97057734
- Cohen SR; Hassan SA; Lapointe BJ; Mount BM; Department of Oncology, McGill University, Montreal, Quebec, Canada.
- OBJECTIVE: To test the acceptability, validity, and internal consistency reliability of the McGill quality of life questionnaire (MQOL) for persons living with HIV/AIDS. DESIGN: The validity of MQOL was tested by having HIV-seropositive outpatients complete the 16-item MQOL, a single-item scale (SIS) measuring overall
- Can we reduce the burden of morbidity in HIV-infected injecting drug users? [editorial; comment]
- AIDS. 1996 Oct;10(12):1429-30. Unique Identifier : AIDSLINE MED/97057735
- Selwyn PA
- Serum levels of RANTES and MIP-1 alpha in HIV-positive long-term survivors and progressor patients [letter]
- AIDS. 1996 Oct;10(12):1431-2. Unique Identifier : AIDSLINE MED/97057736
- Zanussi S; D'Andrea M; Simonelli C; Tirelli U; De Paoli P
- Chemokine production in HIV-seropositive long-term asymptomatic individuals [letter]
- AIDS. 1996 Oct;10(12):1432-3. Unique Identifier : AIDSLINE MED/97057737
- Clerici M; Balotta C; Trabattoni D; Papagno L; Ruzzante S; Rusconi S; Fusi ML; Colombo MC; Galli M
- CD8+ T-cell-mediated suppression of HIV-1 infection may not be due to chemokines RANTES, MIP-1 alpha and MIP-1 beta [letter]
- AIDS. 1996 Oct;10(12):1434-5. Unique Identifier : AIDSLINE MED/97057738
- Chen Y; Gupta P
- RANTES, MIP and interleukin-16 in HIV infection [letter]
- AIDS. 1996 Oct;10(12):1435-6. Unique Identifier : AIDSLINE MED/97057739
- Blazevic V; Heino M; Ranki A; Jussila T; Krohn KJ
- Marked activation of the tumour necrosis factor system in AIDS-associated cryptococcosis [letter]
- AIDS. 1996 Oct;10(12):1436-8. Unique Identifier : AIDSLINE MED/97057740
- Mastroianni CM; Lichtner M; Mengoni F; Santopadre P; Vullo V; Delia S
- Susceptibility of peripheral blood mononuclear cells from gorillas, orangutans and baboons to diverse HIV isolates [letter]
- AIDS. 1996 Oct;10(12):1438-40. Unique Identifier : AIDSLINE MED/97057741
- Locher CP; Blackbourn DJ; Castro BA; Brasky KM; Levy JA
- Cytotoxic T-lymphocyte response induced by a V3 loop synthetic peptide from an African HIV-1 isolate is cross-reactive against HIV-1 strains from North America/Europe region [letter]
- AIDS. 1996 Oct;10(12):1440-1. Unique Identifier : AIDSLINE MED/97057742
- Casement KS; Arlinghaus KB; Sastry KJ
- Identification of a novel human leukocyte antigen A26-restricted epitope in a conserved region of Gag [letter]
- AIDS. 1996 Oct;10(12):1441-3. Unique Identifier : AIDSLINE MED/97057743
- Goulder P; Conlon C; Mclntyre K; McMichael A
- Cerebral proton magnetic resonance spectroscopy in cytomegalovirus encephalitis and HIV leucoencephalopathy/encephalitis [letter]
- AIDS. 1996 Oct;10(12):1443-4. Unique Identifier : AIDSLINE MED/97057744
- Wilkinson ID; Miller RF; Paley MN; Miszkiel KA; Kendall BE; Hall-Craggs MA; Harrison MJ
- CD4+ lymphocyte count variations in HIV-negative subjects treated with zidovudine [letter]
- AIDS. 1996 Oct;10(12):1444-5. Unique Identifier : AIDSLINE MED/97057745
- Milazzo L; Vaira LM; Cremoni L
- The influence of intravenous drug use and HIV infection in the transmission of tuberculosis [letter; comment]
- AIDS. 1996 Oct;10(12):1445-6. Unique Identifier : AIDSLINE MED/97057746
- Collazos J; Gonzalez-Bricio A
- The influence of intravenous drug use and HIV infection in the transmission of tuberculosis [letter]
- AIDS. 1996 Oct;10(12):1446-7. Unique Identifier : AIDSLINE MED/97057747
- Cayla JA; Garcia de Olalla P; Galdos-Tanguis H; Vidal R; Lopez-Colomes JL; Gatell JM; Jansa JM
- HIV among drug users in regional towns near the initial focus of the Dutch epidemic [letter]
- AIDS. 1996 Oct;10(12):1448-9. Unique Identifier : AIDSLINE MED/97057748
- Wiessing LG; Houweling H; Spruit IP; Korf DJ; van Duynhoven YT; Fennema JS; Borgdorff MW
- Job's syndrome associated with HIV infection improved with immune globulin therapy [letter]
- AIDS. 1996 Oct;10(12):1449-50. Unique Identifier : AIDSLINE MED/97057749
- Domingo P; Ris J; Puig M; Lopez-Contreras J
- Plasma levels of soluble CD30, tumour necrosis factor (TNF)-alpha and TNF receptors during primary HIV-1 infection: correlation with HIV-1 RNA and the clinical outcome.
- AIDS. 1996 Nov;10(13):F45-50. Unique Identifier : AIDSLINE MED/97085691
- Rizzardi GP; Barcellini W; Tambussi G; Lillo F; Malnati M; Perrin L; Lazzarin A; Institute of Internal Medicine, Infectious Diseases and; Immunopathology, University of Milan, Italy.
- OBJECTIVES: The immunological and virological events associated with primary HIV-1 infection have a major impact on the course of HIV-1 disease, and the identification of early predictors during primary HIV infection is critical for the therapeutic strategy. DESIGN AND METHODS: Eighteen consecutive patients with prima
- Testing for HIV at home: what are the issues? [editorial] [see comments]
- AIDS. 1996 Nov;10(13):1455-65. Unique Identifier : AIDSLINE MED/97085692
- Schopper D; Vercauteren G
- Identification of cell subsets expressing intracytoplasmic cytokines within HIV-1-infected lymph nodes.
- AIDS. 1996 Nov;10(13):1467-75. Unique Identifier : AIDSLINE MED/97085693
- Gray CM; Morris L; Murray J; Keeton J; Shalekoff S; Lyons SF; Sonnenberg P; Martin DJ; Medical Research Council AIDS Virus Research Unit, National Institute; for Virology, Johannesburg, South Africa.
- OBJECTIVE: To describe the endogenous cytokine profile of HIV-1-infected lymph nodes (LN) and to identify the phenotype of individual cells expressing intracytoplasmic cytokines. DESIGN AND METHODS: Whole LN biopsies were collected from three HIV-seronegative controls and four HIV-1-positive individuals with persisten
- CD4+ memory T cells are the predominant population of HIV-1-infected lymphocytes in neonates and children.
- AIDS. 1996 Nov;10(13):1477-84. Unique Identifier : AIDSLINE MED/97085694
- Sleasman JW; Aleixo LF; Morton A; Skoda-Smith S; Goodenow MM; Department of Pediatrics, University of Florida College of Medicine,; Gainesville 32610-0296, USA.
- BACKGROUND: CD4+ memory T cells express CD45RO and are the principal viral reservoir in HIV-infected adults. In infants and children, CD45RO T cells comprise the minority of the CD4+ T-cell population. The majority of blood CD4+ T cells are naive, expressing CD45RA. OBJECTIVE: To determine the developmental stage at w
- Phylogenetic analysis of the env gene of HIV-1 isolates taking into account individual nucleotide substitution rates.
- AIDS. 1996 Nov;10(13):1485-94. Unique Identifier : AIDSLINE MED/97085695
- Van de Peer Y; Janssens W; Heyndrickx L; Fransen K; van der Groen G; De Wachter R; Department of Biochemistry, University of Antwerp, Belgium.
- OBJECTIVE: To estimate the relative substitution rate of the individual positions in an alignment of HIV-1 env sequences coding for areas V3, V4, V5, and the beginning of gp41, and to study phylogenetic relationships between HIV-1 strains taking into account these substitution rate estimates. DESIGN: Phylogenetic comp
- Monokine products as predictors of AIDS dementia.
- AIDS. 1996 Nov;10(13):1495-500. Unique Identifier : AIDSLINE MED/97085696
- Pulliam L; Clarke JA; McGrath MS; Moore D; McGuire D; Department of Laboratory Medicine, Veterans Affairs Medical Center,; San Francisco, CA 94121, USA.
- OBJECTIVE: To determine whether or not soluble factors produced by peripheral blood mononuclear cells (PBMC) can predict AIDS dementia . DESIGN AND METHODS: PBMC were isolated from individuals with and without AIDS dementia complex (ADC) to determine if the levels of cytokines tumou
- Effects of thalidomide on HIV-associated wasting syndrome: a randomized, double-blind, placebo-controlled clinical trial.
- AIDS. 1996 Nov;10(13):1501-7. Unique Identifier : AIDSLINE MED/97085697
- Reyes-Teran G; Sierra-Madero JG; Martinez del Cerro V; Arroyo-Figueroa H; Pasquetti A; Calva JJ; Ruiz-Palacios GM; Department of Infectious Diseases, Instituto Nacional de la Nutricion; Salvador Zubiran, Tlalpan, Mexico, D.F., Mexico.
- OBJECTIVE: To evaluate the efficacy of thalidomide in treating wasting syndrome in patients with advanced HIV disease, and to assess the effects of thalidomide on circulating CD4+ T cells, and on HIV viral burden in peripheral blood mononuclear cells PBMC). DESIGN: Randomized, double-blind placebo-controlled clinical
- Impaired absorption of zidovudine in patients with AIDS-related small intestinal disease.
- AIDS. 1996 Nov;10(13):1509-14. Unique Identifier : AIDSLINE MED/97085698
- Kapembwa MS; Fleming SC; Orr M; Wells C; Bland M; Back D; Griffin GE; Department of Genitourinary Medicine, Imperial College of Science, St; Mary's Hospital Medical School, London, UK.
- OBJECTIVES: To investigate the effect of small intestinal disease SID) on the absorption of zidovudine (ZDV) in patients with AIDS. METHODS: Fourteen fasted homosexual men with AIDS received a single oral dose of ZDV (5 mg/kg). Nine subjects had clinical evidence of intestinal disease (chronic diarrhoea with wasting)
- Cytomegalovirus retinitis in AIDS patients: influence of cytomegaloviral load on response to ganciclovir, time to recurrence and survival.
- AIDS. 1996 Nov;10(13):1515-20. Unique Identifier : AIDSLINE MED/97085699
- Bowen EF; Wilson P; Cope A; Sabin C; Griffiths P; Davey C; Johnson M; Emery V; Department of Virology, Royal Free Hospital and School of Medicine,; London, UK.
- OBJECTIVES: Despite life-long maintenance therapy, cytomegalovirus ( CMV ) retinitis frequently progresses in patients with AIDS. Virological markers that could clarify pathogenesis and identify risk factors for progression are
- Predictive value of Toxoplasma gondii antibody titres on the occurrence of toxoplasmic encephalitis in HIV-infected patients. ANRS 005/ACTG 154 Trial Group.
- AIDS. 1996 Nov;10(13):1521-7. Unique Identifier : AIDSLINE MED/97085700
- Derouin F; Leport C; Pueyo S; Morlat P; Letrillart B; Chene G; Ecobichon JL; Luft B; Aubertin J; Hafner R; Vilde JL; Salamon R; Laboratory of Parasitology, Saint-Louis Hospital, Paris, France.
- OBJECTIVE: To study the predictive value of anti-Toxoplasma gondii antibody titres for the occurrence of toxoplasmic encephalitis (TE) in HIV-infected patients. METHODS: Data from the placebo arm of a trial of primary prophylaxis for TE (ANRS 005/ACTG 154) were analysed. Patients included had CD4+ cell counts
- The metabolic response to opportunistic infections in AIDS.
- AIDS. 1996 Nov;10(13):1529-33. Unique Identifier : AIDSLINE MED/97085701
- Sharpstone DR; Ross HM; Gazzard BG; Department of HIV/Genito-Urinary Medicine, Chelsea and Westminster; Hospital, London, UK.
- OBJECTIVE: The metabolic response to AIDS-defining opportunistic infections was examined to provide a logical basis for the management of associated weight loss. DESIGN: A prospective study of metabolism in AIDS. SETTING: HIV outpatients department and wards at the Chelsea and Westminster Hospital, London. PATIENTS:
- Immunological activation markers in the serum of African and European HIV-seropositive and seronegative individuals.
- AIDS. 1996 Nov;10(13):1535-42. Unique Identifier : AIDSLINE MED/97085702
- Rizzardini G; Piconi S; Ruzzante S; Fusi ML; Lukwiya M; Declich S; Tamburini M; Villa ML; Fabiani M; Milazzo F; Clerici M; First Division of Infectious Disease, University of Milan, Luigi Sacco; Hospital, Italy.
- OBJECTIVE: The concentration of type 1 and type 2 cytokines and fibroblast-associated apoptosis-1 soluble receptor (sAPO-1/Fas) was analysed in the sera of Ugandan and Italian HIV-1-seropositive and seronegative individuals. The data were compared to determine whether the immunological status of these groups was diffe
- Chlamydia pneumoniae seroprevalence among HIV-1-infected and uninfected people with known HIV risk factor.
- AIDS. 1996 Nov;10(13):1543-7. Unique Identifier : AIDSLINE MED/97085703
- Viscott Comandini U; Massetti AP; Marchese R; Zaccarelli M; Vullo V; Delia S; Department of Infectious and Tropical Diseases, La Sapienza; University, Rome, Italy.
- OBJECTIVE: To evaluate the prevalence of Chlamydia pneumoniae antibodies in an Italian population of HIV-infected and uninfected individuals in relation to the presence of HIV risk factors. DESIGN AND METHODS: A prospective evaluation of C. pneumoniae microimmunofluorescence immunoglobulin (Ig) G and IgM titres, in re
- Reasons for HIV antibody test refusal in a heterosexual sexually transmitted disease clinic population.
- AIDS. 1996 Nov;10(13):1549-53. Unique Identifier : AIDSLINE MED/97085704
- Simon PA; Weber M; Ford WL; Cheng F; Kerndt PR; HIV Epidemiology Program, Los Angeles County Department of Health; Services, California 90005, USA.
- OBJECTIVE: To evaluate acceptance of confidential HIV antibody testing and reasons for test refusal among heterosexual clients of Los Angeles County sexually transmitted disease (STD) clinics. METHODS: From January 1993 through June 1994, all blood specimens routinely collected for syphilis serology were tested blindl
- The feasibility of HIV-1 vaccine efficacy trials among gay/bisexual men in New York City: Project ACHIEVE. AIDS Community Health Initiative Enroute to the Vaccine EFfort.
- AIDS. 1996 Nov;10(13):1555-61. Unique Identifier : AIDSLINE MED/97085705
- Koblin BA; Taylor PE; Avrett S; Stevens CE; Wolf Szmuness Laboratory of Epidemiology, New York Blood Center, New; York 10021, USA.
- OBJECTIVE: Candidate populations for HIV-1 vaccine efficacy trials need to be at high risk of infection, adhere to study protocols and be willing to participate. The goal of Project ACHIEVE is to collect baseline data needed in order to prepare for vaccine efficacy trials among gay/bisexual men in New York City. DESIG
- Spectrum of disease in Africans with AIDS in London.
- AIDS. 1996 Nov;10(13):1563-9. Unique Identifier : AIDSLINE MED/97085706
- Del Amo J; Petruckevitch A; Phillips AN; Johnson AM; Stephenson JM; Desmond N; Hanscheid T; Low N; Newell A; Obasi A; Paine K; Pym A; Theodore CM; De Cock KM; Department of STD, Mortimer Market Centre, London, UK.
- OBJECTIVE: To compare the spectrum of disease, severity of immune deficiency and chemoprophylaxis prescribed in HIV-infected African and non-African patients in London. DESIGN: Retrospective review of case notes of all HIV-infected Africans and a comparison group of non-Africans attending 11 specialist HIV/AIDS Units
- United Kingdom AIDS survival in adults.
- AIDS. 1996 Nov;10(13):1571-8. Unique Identifier : AIDSLINE MED/97085707
- Rogers PA; Gore SM; Whitmore-Overton SE; Allardice GM; Swan AV; Noone A; Public Health Laboratory Service (PHLS) Statistics Unit, Communicable; Disease Surveillance Centre, London, UK.
- OBJECTIVE: To examine the impact of age, year and region of AIDS diagnosis on early (up to 12 months) and late survival of AIDS patients in different exposure categories; to describe the hazard pattern from 12 months after AIDS diagnosis. PATIENTS: A total of 4577 UK adult AIDS diagnoses to the end of 1991 in men who
- Distribution of HIV-1 subtypes seen in an AIDS clinic in Sao Paulo City, Brazil.
- AIDS. 1996 Nov;10(13):1579-84. Unique Identifier : AIDSLINE MED/97085708
- Sabino EC; Diaz RS; Brigido LF; Learn GH; Mullins JI; Reingold AL; Duarte AJ; Mayer A; Busch MP; Instituto Adolfo Lutz, Sao Paulo, Brazil.
- OBJECTIVE: To determine the distribution of HIV-1 subtypes in Sao Paulo, Brazil . METHODS: Samples were obtained from 80 consecutive HIV-1-infected individuals attending the Immunodeficiency Clinic at the University of Sao Paulo in 1993. Peripheral blood mononuclear cells (PBMC) wer
- Age of wife as a major determinant of male-to-female transmission of HIV-2 infection: a community study from rural West Africa.
- AIDS. 1996 Nov;10(13):1585-90. Unique Identifier : AIDSLINE MED/97085709
- Aaby P; Ariyoshi K; Buckner M; Jensen H; Berry N; Wilkins A; Richard D; Larsen O; Dias F; Melbye M; Whittle H; Department of Epidemiology Research, Danish Epidemiology Science; Centre, Statens Seruminstitut, Copenhagen, Denmark.
- OBJECTIVE: To examine whether proviral load is important for transmission between spouses, since we have previously found that the proviral load of HIV-2 predicts the severity of infection. DESIGN: Proviral load was examined in 121 HIV-2-infected adults in a rural area of Guinea-Bissa
- HIV therapy in the real world [editorial]
- AIDS. 1996 Nov;10(13):1591-3. Unique Identifier : AIDSLINE MED/97085710
- Selwyn PA
- The sex ratio of AIDS-associated Kaposi's sarcoma does not provide evidence that sex hormones play a role in pathogenesis [letter]
- AIDS. 1996 Nov;10(13):1595-6. Unique Identifier : AIDSLINE MED/97085711
- Grulich AE; Kaldor JM
- Detection of Kaposi's sarcoma herpesvirus DNA in semen of homosexual men with Kaposi's sarcoma [letter]
- AIDS. 1996 Nov;10(13):1596-8. Unique Identifier : AIDSLINE MED/97085712
- Gupta P; Singh MK; Rinaldo C; Ding M; Farzadegan H; Saah A; Hoover D; Moore P; Kingsley L
- Syncytium-inducing HIV-1 variants replicate equally well in all types of T-helper cell clones [letter]
- AIDS. 1996 Nov;10(13):1598-600. Unique Identifier : AIDSLINE MED/97085713
- Meyaard L; Fouchier RA; Brouwer M; Hovenkamp E; Miedema F
- Better prediction of vertical HIV-1 transmission from maternal blood at delivery compared with cord blood samples [letter]
- AIDS. 1996 Nov;10(13):1600-1. Unique Identifier : AIDSLINE MED/97085714
- Zollner B; Feucht HH; Mattner UM; Helling-Giese G; Baumgartner EM; Laufs R
- Temporal trends of the natural history of HIV-1 infection following seroconversion between 1984 and 1993 [letter]
- AIDS. 1996 Nov;10(13):1601-2. Unique Identifier : AIDSLINE MED/97085715
- Keet IP; Veugelers PJ; Koot M; de Weerd MH; Roos MT; Miedema F; de Wolf F; Goudsmit J; Coutinho RA
- Secondary Pneumocystis carinii pneumonia prophylaxis with trimethoprim-sulphamethoxazole does not prevent bacterial pneumonia in HIV-infected persons [letter]
- AIDS. 1996 Nov;10(13):1603-4. Unique Identifier : AIDSLINE MED/97085716
- Tumbarello M; Tacconelli E; Cauda R; Ortona L
- AIDS-related varicella zoster meningoencephalitis and radicular pain without cutaneous eruption [letter]
- AIDS. 1996 Nov;10(13):1604-6. Unique Identifier : AIDSLINE MED/97085717
- Debat Zoguereh D; Saadoun R; Zandotti C; Cawston P; Moreau J
- Thrombocytopenia and AIDS: possible direct role of HIV [letter]
- AIDS. 1996 Nov;10(13):1606-8. Unique Identifier : AIDSLINE MED/97085718
- Borgia G; Reynaud L; Cicciarello S; Tallarino A; Fratellanza G; Lambiase A; Nasti G; Simonelli C; Foggia M; Tirelli U; Piazza M
- Compulsory HIV testing: medical students' views [letter]
- AIDS. 1996 Nov;10(13):1608-9. Unique Identifier : AIDSLINE MED/97085719
- Williams S; Elford J; Cockcroft A
- Nosocomial outbreak of tuberculosis in an outpatient HIV treatment room [letter; comment]
- AIDS. 1996 Nov;10(13):1609. Unique Identifier : AIDSLINE MED/97085720
- Singh G
- Perspective: research highlights at the Dana-Farber Cancer Institute Center for AIDS Research (CFAR).
- AIDS Res Hum Retroviruses. 1996 Nov 1;12(16):1499-502. Unique Identifier : AIDSLINE MED/97068246
- Sodroski J; Dana-Farber Cancer Institute, Department of Pathology, Harvard Medical; School, Boston, Massachusetts, USA.
- V3 loop sequence analysis of seven HIV type 1 group O isolates phenotyped in peripheral blood mononuclear cells and MT-2 cells.
- AIDS Res Hum Retroviruses. 1996 Nov 1;12(16):1503-7. Unique Identifier : AIDSLINE MED/97068247
- De Jong J; Simon F; Van der Groen G; Baan E; Saragosti S; Brun-Vezinet F; Goudsmit J; Department of Human Retrovirology, Academic Medical Centre, Amsterdam,; The Netherlands.
- HIV-1-infected individuals from which syncytium-inducing (SI) viruses are isolated most often progress more rapidly to AIDS than individuals carrying only non-syncytium-inducing (NSI) viruses. The syncytium-inducing capacity of virus isolates is commonly determined in conjunction to replication in MT-2 cells. Comparis
- Neutralization of HIV type 1 infectivity by serum antibodies from a subset of autoimmune patients with mixed connective tissue disease.
- AIDS Res Hum Retroviruses. 1996 Nov 1;12(16):1509-17. Unique Identifier : AIDSLINE MED/97068248
- Douvas A; Takehana Y; Ehresmann G; Chernyovskiy T; Daar ES; Department of Medicine, University of Southern California School of; Medicine, Los Angeles 90033, USA.
- Mixed connective tissue disease (MCTD) is a rheumatic disorder with clinical similarities to HIV-1 infection, and with characteristic autoimmune anti-RNP antibodies specific for the U1 snRNP splicing complex. Anti-RNP antibodies cross-react with the HIV-1 surface, owing to multiple homologies between the gp120/41 enve
- Activation of the HIV type 1 long terminal repeat by X-irradiation involves two main Re1/NF-kappa B DNA-binding complexes.
- AIDS Res Hum Retroviruses. 1996 Nov 1;12(16):1519-27. Unique Identifier : AIDSLINE MED/97068249
- Faure E; Lecine P; Imbert J; Champion S; Institut de Chimie Biologique, Universite de Provence, Marscelle,; France.
- Transcription of human immunodeficiency virus type 1 (HIV-1) is regulated by multiple cis-acting regulatory elements located in the viral long terminal repeats (LTRs). HIV-1 LTR enhancer is activated by a variety of heterologous viral, chemical, and physical agents. Studies have demonstrated that irradiation by X-rays
- Effect of HIV type 1 Tat protein on butyric acid-induced differentiation in a hematopoietic progenitor cell line.
- AIDS Res Hum Retroviruses. 1996 Nov 1;12(16):1529-36. Unique Identifier : AIDSLINE MED/97068250
- Mondal D; Agrawal KC; Department of Pharmacology, Tulane University School of Medicine, New; Orleans, Louisiana 70112, USA.
- The trans-activator protein (Tat) of HIV-1 plays an important role in viral pathogenesis. Since Tat has been shown to alter expression of a number of host cellular genes, we have investigated the role of Tat in modulating gene expression and differentiation in hematopoietic progenitor cells. Tat protein was introduced
- Glutathione inhibits HIV replication by acting at late stages of the virus life cycle.
- AIDS Res Hum Retroviruses. 1996 Nov 1;12(16):1537-41. Unique Identifier : AIDSLINE MED/97068251
- Palamara AT; Perno CF; Aquaro S; Bue MC; Dini L; Garaci E; Department of Experimental Medicine and Biochemical Sciences,; University of Rome, Italy.
- We investigated the effect of glutathione on the replication of human immunodeficiency virus (HIV) in chronically infected macrophages, a known reservoir of the virus in the body. We found that exogenous GSH strongly suppresses the production of p24gag protein as well as the virus infectivity. This is related to a dra
- A high frequency of defective vif genes in peripheral blood mononuclear cells from HIV type 1-infected individuals.
- AIDS Res Hum Retroviruses. 1996 Nov 1;12(16):1543-9. Unique Identifier : AIDSLINE MED/97068252
- Tominaga K; Kato S; Negishi M; Takano T; Department of Microbiology, Keio University School of Medicine, Tokyo,; Japan.
- We studied the heterogeneity and intactness of the vif gene in six HIV-1-infected individuals at various clinical stages. The proviral vif sequences in peripheral blood mononuclear cells were amplified by PCR, followed by cloning and sequencing of 45 vif clones. The intraindividual diversity of the vif genes ranged fr
- HIV type 1 RNA expression in bone marrows of patients with a spectrum of disease.
- AIDS Res Hum Retroviruses. 1996 Nov 1;12(16):1551-8. Unique Identifier : AIDSLINE MED/97068253
- Weiser B; Burger H; Campbell P; Donelan S; Mladenovic J; Wadsworth Center, New York State Department of Health and Albany; Medical College, New York 12201-2002, USA.
- HIV-1-infected individuals at various stages of disease harbor virus in their lymphoid organs, which serve as reservoirs of viral replication throughout the course of infection. Hematologic abnormalities are extremely common in HIV-1-infected individuals and occur at all stages of disease. To determine if the bone mar
- Early impairment of systolic and diastolic function in asymptomatic HIV-positive patients: a multicenter echocardiographic and echo-Doppler study. The Gruppo Italiano Per lo Studio Cardiologico dei Pazienti Affetti da AIDS.
- AIDS Res Hum Retroviruses. 1996 Nov 1;12(16):1559-63. Unique Identifier : AIDSLINE MED/97068254
- Barbaro G; Barbarini G; Di Lorenzo G; Department of Emergency Medicine, University La Sapienza, Rome, Italy.
- Human immunodeficiency virus (HIV) possesses an intrinsic cardiopathogenic action that may be detected even in the early stages of HIV disease. To assess an early impairment of systolic and diastolic function in asymptomatic HIV-positive patients CD4+ > or = 600/mm3), we performed a multicenter echocardiographic and e
- Workshop on perinatally acquired human immunodeficiency virus infection in long-term surviving children: a collaborative study of factors contributing to slow disease progression. The Long-Term Survivor Project.
- AIDS Res Hum Retroviruses. 1996 Nov 1;12(16):1565-70. Unique Identifier : AIDSLINE MED/97068255
- Martin N; Koup R; Kaslow R; Coffin J; Ammann A; Pediatric AIDS Foundation, Novato, California 94949, USA.
- Characterization of V3 loop of HIV type 1 spreading rapidly among injection drug users of Manipur, India: a molecular epidemiological perspective.
- AIDS Res Hum Retroviruses. 1996 Nov 1;12(16):1571-3. Unique Identifier : AIDSLINE MED/97068256
- Panda S; Wang G; Sarkar S; Perez CM; Chakraborty S; Agarwal A; Dorman K; Sarkar K; Detels R; Kaplan AH; Indian Council of Medical Research (ICMR) Unit for Research on AIDS,; Salt Lake, Calcutta, India.
- Genetic and phylogenetic analysis of HIV type 1 env subtypes in Ghana, west Africa.
- AIDS Res Hum Retroviruses. 1996 Nov 1;12(16):1575-8. Unique Identifier : AIDSLINE MED/97068257
- Ishikawa K; Janssens W; Brandful J; Heyndrickx L; Takebe Y; Ampofo W; Sata T; Yamazaki S; Osei-Kwasi M; Yamamoto N; Koyanagi Y; Van der Groen G; Kurata T; Laboratory of AIDS Pathology, National Institute of Health, Tokyo,; Japan.
- Unraveling the function of HIV type 1 Nef.
- AIDS Res Hum Retroviruses. 1996 Nov 20;12(17):1579-82. Unique Identifier : AIDSLINE MED/97102919
- Geleziunas R; Miller MD; Greene WC; Gladstone Institute of Virology and Immunology, University of; California, San Francisco 94141, USA.
- Syndrome of recurrent transient neurological deficits in patients with HIV infection [letter]
- AIDS Res Hum Retroviruses. 1996 Nov 20;12(17):1583. Unique Identifier : AIDSLINE MED/97102920
- Manfredi R; Azzimondi G; Rinaldi R; Tonon C; Mastroianni A; Coronado OV; D'Alessandro R; Chiodo F
- In vitro characterization of HIV type 1 biological clones from asymptomatic and symptomatic pediatric patients.
- AIDS Res Hum Retroviruses. 1996 Nov 20;12(17):1585-93. Unique Identifier : AIDSLINE MED/97102921
- Forte SE; Sullivan JL; Somasundaran M; Department of Pediatrics, University of Massachusetts Medical Center,; Worcester 01605, USA.
- To investigate the mechanisms of HIV-1 cytopathogenicity, functional biological HIV-1 clones were isolated from two infected children with high viral loads in vivo. Clone HC4 was isolated from a symptomatic child and clone GC6 8-4 was isolated from an asymptomatic child. These clones were characterized for their abili
- Molecular epidemiology and MT-2 cell tropism of Russian HIV type 1 variant.
- AIDS Res Hum Retroviruses. 1996 Nov 20;12(17):1595-603. Unique Identifier : AIDSLINE MED/97102922
- Leitner T; Korovina G; Marquina S; Smolskaya T; Albert J; Department of Clinical Virology, Swedish Institute for Infectious; Disease Control, Karolinska Institute, Stockholm, Sweden.
- Twenty-two HIV-1-infected Russian individuals were studied to gain better insight on the genetic and biological characteristics of HIV-1 variants present in Russia. The V3 domain of the HIV-1 envelope was directly sequenced from cultured peripheral blood mononuclear cells (PBMCs). Phylogenetic analyses were used to de
- Lentiviral genomes with G-to-A hypermutation may result from Taq polymerase errors during polymerase chain reaction.
- AIDS Res Hum Retroviruses. 1996 Nov 20;12(17):1605-13. Unique Identifier : AIDSLINE MED/97102923
- Overbaugh J; Jackson SM; Papenhausen MD; Rudensey LM; Department of Microbiology, University of Washington, Seattle 98195,; USA.
- Retroviral genomes with a high frequency of G-to-A mutations are thought to originate during reverse transcription. Here we show that bursts of G-to-A mutation may also occur during DNA synthesis by Taq polymerase on a simian immunodeficiency proviral template. These G-to-A changes tend to occur at GpA and, to a lesse
- Alteration of CD44 expression in HIV type 1-infected T cell lines.
- AIDS Res Hum Retroviruses. 1996 Nov 20;12(17):1615-22. Unique Identifier : AIDSLINE MED/97102924
- Giordanengo V; Limouse M; Doglio A; Lesimple J; Lefebvre JC; Laboratoire de Virologie, Faculte de Medecine, Nice, France.
- CD44 is known to interfere in HIV replication and to participate in many physiological processes such as lymphocyte binding to high endothelial venules of lymphoid tissue, lymph nodes, and mucosal endothelium. The T cell lines MOLT-4 and CEM, and CEM subclones were infected with the HIV-1 LAI strain and monitored for
- Twenty-five years of HTLV type II follow-up with a possible case of tropical spastic paraparesis in the Kayapo, a Brazilian Indian tribe.
- AIDS Res Hum Retroviruses. 1996 Nov 20;12(17):1623-7. Unique Identifier : AIDSLINE MED/97102925
- Black FL; Biggar RJ; Lal RB; Gabbai AA; Filho JP; Department of Public Health, Yale University, School of Medicine, New; Haven, Connecticut 06520-8034, USA.
- A longitudinal study, spanning 25 years and great demographic and cultural change, found a persistently high prevalence of human T-lymphotropic virus type II (HTLV-II) in the Xikrin Kayapo Indians of Brazil . More than 10% of the children continue to develop immune reactions to the
- Infection of human T lymphoid cells by human herpesvirus 6 is blocked by two unrelated protein tyrosine kinase inhibitors, biochanin A and herbimycin.
- AIDS Res Hum Retroviruses. 1996 Nov 20;12(17):1629-34. Unique Identifier : AIDSLINE MED/97102926
- Cirone M; Zompetta C; Tarasi D; Frati L; Faggioni A; Dipartimento di Medicina Sperimentale e Patologia, Universita degli; Studi La Sapienza, Rome, Italy.
- Human herpesvirus 6 is a T lymphotropic herpesvirus that causes exanthem subitum in infants and is considered a potential cofactor in AIDS etiopathogenesis and progression owing to its in vivo and in vitro interactions with human immunodeficiency virus. We report that no differences in phosphorylation on tyrosine resi
- Intracellular glutathione as a possible direct blocker of HIV type 1 reverse transcription.
- AIDS Res Hum Retroviruses. 1996 Nov 20;12(17):1635-8. Unique Identifier : AIDSLINE MED/97102927
- Kameoka M; Okada Y; Tobiume M; Kimura T; Ikuta K; Section of Serology, Hokkaido University, Sapporo, Japan.
- In AIDS patients, chronic inflammation and elevated levels of cytokines seem to be associated with reduced levels of glutathione (GSH). GSH has been proposed to inhibit the activation of NF-kB, which results in the inhibition of HIV-1 replication. Here, we show the evidence that GSH and N-acetylcysteine, but not L-cys
- Elevated hepatic gamma-glutamylcysteine synthetase activity and abnormal sulfate levels in liver and muscle tissue may explain abnormal cysteine and glutathione levels in SIV-infected rhesus macaques.
- AIDS Res Hum Retroviruses. 1996 Nov 20;12(17):1639-41. Unique Identifier : AIDSLINE MED/97102928
- Gross A; Hack V; Stahl-Hennig C; Droge W; Department of Immunochemistry, Deutsches Krebsforschungszentrum,; Heidelberg, Germany.
- To establish whether the low cysteine and glutathione levels in HIV-infected patients and SIV-infected rhesus macaques may be consequences of an abnormal cysteine catabolism, we analyzed sulfate and glutathione levels in macaques. Muscle tissue (m. vastus lateralis and m. gastrocnemius) of SIV-infected macaques n = 25
- Genetic and biological analysis of variants derived from the cerebrospinal fluid of HIV type 1 subtype B- and D- infected patients with and without AIDS dementia complex.
- AIDS Res Hum Retroviruses. 1996 Nov 20;12(17):1643-5. Unique Identifier : AIDSLINE MED/97102929
- Brengel-Pesce K; Morand P; Innocenti-Francillard P; Chanzy B; Bourgeat MJ; Leclercq P; Micoud M; Seigneurin JM; Laboratoire de Virologie-RAHP, Faculte de Medicine de Grenoble, La; Tronche, France.
- Env gene characterization of the first HIV type 1 group O Spanish isolate.
- AIDS Res Hum Retroviruses. 1996 Nov 20;12(17):1647-9. Unique Identifier : AIDSLINE MED/97102930
- Mas A; Quinones-Mateu E; Soriano V; Domingo E; Servicio de Enfermedades Infecciosas, Instituto de Salud Carlos III,; Madrid, Spain.
- Coexistence of subtypes B, F, and as B/F env recombinant of HIV type 1 in Buenos Aires Argentina.
- AIDS Res Hum Retroviruses. 1996 Nov 20;12(17):1651-4. Unique Identifier : AIDSLINE MED/97102931
- Marquina S; Leitner T; Rabinovich RD; Benetucci J; Libonatti O; Albert J; Department of Microbiology, University of Buenos Aires, School of; Medicine, Argentina.
- HIV type 1 subtypes in Malaysia include B, C, and E.
- AIDS Res Hum Retroviruses. 1996 Nov 20;12(17):1655-7. Unique Identifier : AIDSLINE MED/97102932
- Brown TM; Robbins KE; Sinniah M; Saraswathy TS; Lee V; Hooi LS; Vijayamalar B; Luo CC; Ou CY; Rapier J; Schochetman G; Kalish ML; Division of AIDS/STD/TB/Laboratory Research, Centers for Disease; Control and Prevention, Atlanta, Georgia 30333, USA.
- HIV/AIDS: the global epidemic, December 1996.
- Wkly Epidemiol Rec. 1997 Jan 24;72(4):17-21. Unique Identifier : AIDSLINE MED/97172702
- Cryptococcosis.
- Adv Pharmacol. 1997;37:215-51. Unique Identifier : AIDSLINE MED/97046181
- Aberg JA; Powderly WG; AIDS Clinical Trials Unit, Washington University School of Medicine,; St. Louis, Missouri 63108, USA.
- Structural RNA mimetics: N3'-->P5' phosphoramidate DNA analogs of HIV-1 RRE and TAR RNA form A-type helices that bind specifically to Rev and Tat-related peptides.
- Biochemistry. 1997 Jan 21;36(3):650-9. Unique Identifier : AIDSLINE MED/97164918
- Rigl CT; Lloyd DH; Tsou DS; Gryaznov SM; Wilson WD; Department of Chemistry, Georgia State University, Atlanta 30303, USA.
- An attractive strategy for the development of anti-retroviral drugs is the exploration of compounds that mimic RNA control regions of the viral genome and act as decoys to sequester viral gene regulatory proteins. Decoys consisting of RNA, however, are chemically unstable and readily degraded by cellular nucleases.
- Squamous intraepithelial lesions among adolescent women infected with human immunodeficiency virus [letter]
- J Adolesc Health. 1996 Oct;19(4):246-7. Unique Identifier : AIDSLINE MED/97052467
- Clark R; Kissinger P; Fuller C; Abdalian SE
- Delivery of STD/HIV preventive services to adolescents by primary care physicians.
- J Adolesc Health. 1996 Oct;19(4):249-57. Unique Identifier : AIDSLINE MED/97052468
- Millstein SG; Igra V; Gans J; School of Medicine, University of California, San Francisco 94143 USA.
- PURPOSE: To document the rates of STD/HIV preventive services delivered to adolescents by primary care physicians in California, and to identify variation owing to physician and practice-related factors. METHODS: A stratified random sample of California internists, family physicians, obstetricians-gynecologists, and p
- Sixth and eighth graders and acquired immunodeficiency syndrome: the results of focus group analysis.
- J Adolesc Health. 1996 Oct;19(4):297-302. Unique Identifier : AIDSLINE MED/97052474
- Palmer DA; Boardman B; Bauchner H; Division of General Pediatrics, Boston City Hospital, Boston; University School of Medicine, Massachusetts 02118, USA.
- OBJECTIVE: To determine young adolescents range of factual knowledge and beliefs about human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) among those who have received AIDS education. DESIGN: Focus group analysis. SETTING: Urban middle school. PARTICIPANTS: Two male and two female groups
- Adolescent health in Russia: a view from Moscow and St. Petersburg.
- J Adolesc Health. 1996 Oct;19(4):308-14. Unique Identifier : AIDSLINE MED/97052476
- Blum RW; Blum L; Phillips S; Smith P; Slap G; Department of Pediatrics, University of Minnesota, Minneapolis 55455,; USA.
- PURPOSE: The purpose of this study was to report on the current state of adolescent health in Russia . METHODS: By means of site visits, literature review, discussions with Russian colleagues, and a scientific meeting in Moscow, data were collected on health status of youth, the org
- Tennessee Nurses Association. Resolution. In support of HIV/AIDS preventive vaccine research.
- Tenn Nurse. 1996 Dec;59(6):13, 18. Unique Identifier : AIDSLINE MED/97178208
- HIV/AIDS health worker stress and burnout: introduction and overview [editorial]
- AIDS Care. 1996 Apr;8(2):133-5. Unique Identifier : AIDSLINE MED/97014579
- Miller D; Department of Sexually Transmitted Diseases, University College London; Medical School, London, UK.
- Prediction of grief and HIV/AIDS-related burnout in volunteers.
- AIDS Care. 1996 Apr;8(2):137-43. Unique Identifier : AIDSLINE MED/97014580
- Nesbitt WH; Ross MW; Sunderland RH; Shelp E; Center for Health Promotion Research and Development, School of Public; Health, University of Texas, Houston 77225, USA.
- Burnout in volunteer workers in the HIV/AIDS area results in the loss of dedicated personnel, consequently straining the HIV/AIDS care delivery system. By assessing the predictors of burnout and grief this study describes the role of grief in HIV/AIDS volunteer burnout. Voluntary and anonymous questionnaires were senta
- The relationship between recognition, rewards and burnout in AIDS caring.
- AIDS Care. 1996 Apr;8(2):145-53. Unique Identifier : AIDSLINE MED/97014581
- Bennett L; Ross MW; Sunderland R; Department of Behavioural & Social Sciences in Nursing, The University; of Sydney, Australia.
- The positive psychological and sociological dimensions of AIDS care provision may produce important information to assist burnout prevention. While most studies on stress and burnout in AIDS health care have focused on the negative and difficult aspects of this work, few have considered the notion that the rewards of a
- HIV counsellors' knowledge, attitudes and vulnerabilities to HIV in Lusaka, Zambia, 1994.
- AIDS Care. 1996 Apr;8(2):155-66. Unique Identifier : AIDSLINE MED/97014582
- Baggaley R; Sulwe J; Kelly M; MacMillan MN; Godfrey-Faussett P; Kara Counselling and Training Trust, Lusaka, Zambia.
- The objective of this study was to see how HIV affected counsellors in their personal and professional lives and how they coped. A total of 101 people who were currently working as HIV counsellors were interviewed. Of these, 70 had a relative who had died of HIV, but few had been able to discuss HIV with them. Seventya
- Is there life after work? Experiences of HIV and oncology health staff.
- AIDS Care. 1996 Apr;8(2):167-82. Unique Identifier : AIDSLINE MED/97014583
- Miller D; Gillies P; Department of Sexually Transmitted Diseases, University College London; Medical School, London, UK.
- A cross-sectional interview survey of 103 HIV/AIDS and 100 oncology staff in nine treatment sites in London aimed to identify ways in which work stress affected domestic and social lives of such staff. In all staff one-third of those without long-term emotional relationships stated they felt their work formed a barriea
- Psychological stress in nurses' relationships with HIV-infected patients: the risk of burnout syndrome.
- AIDS Care. 1996 Apr;8(2):183-94. Unique Identifier : AIDSLINE MED/97014584
- Visintini R; Campanini E; Fossati A; Bagnato M; Novella L; Maffei C; Medical Psychology and Psychotherapy Unit, Neuropsychic Science; Department, Istituto Scientifico San Raffaele, Milan, Italy.
- To assess the role played by psychological stress and sociodemographic factors as predictors of burnout in nurses, we administered the AIDS Impact Scale (AIS) and the Maslach Burnout Inventory (MBI) to nurses in the AIDS field. The sample was composed of 410 nurses from 19 departments for the treatment of infectious da
- Burnout, social support and AIDS volunteers.
- AIDS Care. 1996 Apr;8(2):195-206. Unique Identifier : AIDSLINE MED/97014585
- Maslanka H
- Care providers working with people with HIV have shown high levels of burnout (Maslach, 1986) as staff were required to deal with a multi-faceted disease while creating new ways of working with clients. At the same time high burnout levels were also being seen among volunteers who were supplementing the work of paid sa
- Burnout and related factors among HIV/AIDS health care workers.
- AIDS Care. 1996 Apr;8(2):207-21. Unique Identifier : AIDSLINE MED/97014586
- Bellani ML; Furlani F; Gnecchi M; Pezzotta P; Trotti EM; Bellotti GG; Department of Medical Psychology, University of Pavia School of; Medicine at Varese, Regional Psychological AIDS Centre, Varese, Italy.
- A sample of 194 Italian health care-givers working in HIV/AIDS units was assessed to investigate whether there was a correlation between individual variables (socio-demographic and occupational characteristics, personality traits, anxiety, depression, attitudes and emotional reactions) and burnout and job satisfactiona
- AIDS-related beliefs, attitudes and intentions among Malawian students in three secondary schools.
- AIDS Care. 1996 Apr;8(2):223-32. Unique Identifier : AIDSLINE MED/97014587
- Bandawe CR; Foster D; Department of Community Health, College of Medicine, University of; Malawi, Rondebosch, South Africa.
- This preliminary investigation into factors influencing the intention of Malawian secondary school students to engage in low-risk AIDS-related behaviours was based on the Theory of Reasoned Action (Ajzen & Fishbein, 1980). A total of 191 male and female subjects (mean age 19.32) from three secondary schools in Mala
- Research in psychopathology in patients with HIV/AIDS and psychiatric services in Spain.
- AIDS Care. 1996 Apr;8(2):233-9. Unique Identifier : AIDSLINE MED/97014588
- Ayuso Mateos JL; Lastra I; Montanes F; Social Psychiatry Research Unit of Cantabria, University of Cantabria,; Madrid, Spain.
- In this article, we review the research carried out in Spain concerning psychiatric aspects of HIV/AIDS in general, and of suicide and suicidal ideation in particular. The paper presents available information concerning this psychopathology in patients with HIV infection, along with
- Reflections on the 9th International Conference on AIDS Education-- Interventions in Multi-cultural Societies, Israel 25 November-1 December, 1995.
- AIDS Care. 1996 Apr;8(2):241-2. Unique Identifier : AIDSLINE MED/97014589
- Vowles D
- [Aspergillosis and AIDS (editorial)]
- Enferm Infecc Microbiol Clin. 1996 Nov;14(9):517-8. Unique Identifier : AIDSLINE MED/97170442
- Moreno S; Berenguer J
- [Pseudomonas spp. infections in patients with HIV infections]
- Enferm Infecc Microbiol Clin. 1996 Nov;14(9):519-23. Unique Identifier : AIDSLINE MED/97170443
- Payeras A; Riera M; Riera M; Altes J; Homar F; Gil J; Salas A; Villalonga C; Unidad de Enfermedades Infecciosas, Hospital Son Dureta, Palma de; Mallorca.
- BACKGROUND: The aim of this study was to describe the characteristics of the infections by Pseudomonas spp. observed in patients with HIV infection in Spain . METHODS: A retrospective study was performed of the isolations of Pseudomonas spp. in microbiologic samples of patients with
- [Diagnosis of 4 cases of intestinal microsporidiosis in AIDS patients]
- Enferm Infecc Microbiol Clin. 1996 Nov;14(9):533-7. Unique Identifier : AIDSLINE MED/97170446
- Subirats M; Gonzalez-Castelao G; Aguilera O; Moody A; Visvesvara G; Verdejo J; Baquero M; del Aguila C; Servicio de Microbiologia, CIC., Instituto de Salud Carlos III,; Madrid.
- BACKGROUND: Most of the latest clinical and epidemiologic studies indicate that microsporidiosis and above all Enterocytozoon bieneusi cause approximately 7-50% of otherwise unexplained diarrhea in HIV-infected patients. Four cases of intestinal microsporidiosis in AID
- [Colonic tuberculosis as a cause of rectal bleeding in 2 patients with HIV infection]
- Enferm Infecc Microbiol Clin. 1996 Nov;14(9):538-40. Unique Identifier : AIDSLINE MED/97170447
- Pintor E; Piret MV; Velasco M; Barreiro P; Ruiz M; Blanco J; Servicio de Medicina Interna III, Hospital Universitario San Carlos,; Madrid.
- BACKGROUND: Extrapulmonary tuberculosis is a relatively frequent disease in patients with HIV infection. This may be observed coinciding with pulmonary involvement or without diagnostic data of the same. Within extrapulmonary involvement, gastrointestinal involvement is one of the least frequently observed and its dia
- [Oncogenic mechanisms of Epstein-Barr virus]
- Enferm Infecc Microbiol Clin. 1996 Nov;14(9):551-60. Unique Identifier : AIDSLINE MED/97170451
- Herrero JA; Mayo Foundation, Rochester, Minnesota, USA.
- [Is HVH-8 the etiologic agent for Kaposi's sarcoma? (letter; comment)]
- Enferm Infecc Microbiol Clin. 1996 Nov;14(9):569-70. Unique Identifier : AIDSLINE MED/97170455
- Aspiroz MC; Saenz MC
- [Salmonella septic arthritis in a hemophiliac with AIDS: aggressive treatment (letter)]
- Enferm Infecc Microbiol Clin. 1996 Nov;14(9):573-4. Unique Identifier : AIDSLINE MED/97170460
- Ferre R; Martin-Urda A; Vidal F; Richart C
- Specific radioimmunoassays for the measurement of stavudine in human plasma and urine.
- J Pharm Biomed Anal. 1996 Nov;15(2):165-74. Unique Identifier : AIDSLINE MED/97087415
- Kaul S; Stouffer B; Mummaneni V; Turabi N; Mantha S; Jayatilak P; Barbhaiya R; Bristol-Myers Squibb Pharmaceutical Research Institute, Princeton, NJ; 08543, USA.
- Sensitive and specific radioimmunoassays (RIAs) have been developed and validated for the determination of stavudine , a nucleoside analog possessing anti-human immunodeficiency virus HIV) activity, in human plasma and urine. The hemisuccinate of stavu
- Nursing in the urban core [interview by Helen Griffiths]
- Nurs BC. 1996 Nov-Dec;28(5):14-6. Unique Identifier : AIDSLINE MED/97178126
- Brennan E
- [Composition of HIV-1 B-epitopes and heterologous T-cell epitopes. I. Maintenance of antigenic properties of HIV-1 B-epitopes]
- Biokhimiia. 1996 Jul;61(7):1221-9. Unique Identifier : AIDSLINE MED/97000263
- Isaguliants MG; Koshida R; Ruden U; Varen B; Department of Virology, Swedish Institute for Infectious Disease; Control, Stockholm, Sweden.
- Peptides were synthesized combining an immunodominant B-cell epitope from gp41 of HIV-1 with heterogenous T-cell epitopes from tetanus toxoid or hepatitis B core antigen with no spacer bridge between epitopes. The antigenic properties of the B-cell epitope within the composites were evaluated. The majority of the rabb
- [Composition of HIV-1 B-epitopes and heterologous T-cell epitopes. II. Combined analysis of immunogenicity of composite peptides in rabbits]
- Biokhimiia. 1996 Jul;61(7):1230-40. Unique Identifier : AIDSLINE MED/97000264
- Isaruliants MG; Ruden U; Wahren B; Department of Virology, Swedish Institute for Infectious Disease; Control, Stockholm, Sweden.
- Rabbits were immunized with a mixture of linear cojoined peptides composites) combining an immunodominant B-cell epitope from gp41 of HIV-1 (amino acids 593-604) and a heterogeneous T-cell epitope from tetanus toxoid or hepatitis B core antigen. HIV-1 B-epitope in the context of the composites induced HIV-1 specific a
- Drug interactions in patients infected with human immunodeficiency virus.
- Clin Infect Dis. 1996 Oct;23(4):685-93. Unique Identifier : AIDSLINE MED/97066346
- Piscitelli SC; Flexner C; Minor JR; Polis MA; Masur H; Department of Pharmacy, Warren G. Magnuson Clinical Center, National; Institutes of Health, Bethesda, Maryland, USA.
- Patients with AIDS who are receiving optimal medical care, including combination therapy with antiretroviral agents and more effective prophylaxis and therapy for opportunistic infections and neoplasms, are surviving longer. However, the potential for drug interactions
- Cutaneous miliary tuberculosis in the AIDS era: case report and review.
- Clin Infect Dis. 1996 Oct;23(4):706-10. Unique Identifier : AIDSLINE MED/97066349
- Libraty DH; Byrd TF; Department of Medicine, UCLA School of Medicine, USA.
- Tuberculosis with extrapulmonary manifestations is common in patients with AIDS. The skin is a site of dissemination that has often been overlooked. Historically, cutaneous miliary tuberculosis, also known as tuberculosis cutis miliaris disseminata, was noted to be a rare entity in adults; however, over the past 5 yea
- Clindamycin/primaquine as prophylaxis for Pneumocystis carinii pneumonia.
- Clin Infect Dis. 1996 Oct;23(4):718-22. Unique Identifier : AIDSLINE MED/97066352
- Barber BA; Pegram PS; High KP; Department of Internal Medicine, Bowman Gray School of Medicine of; Wake Forest University, Winston-Salem, North Carolina 27157-1042, USA.
- The records of 206 patients with advanced infection due to human immunodeficiency virus type 1 who were receiving prophylaxis with clindamycin/primaquine (C/P), trimethoprim-sulfamethoxazole TMP-SMZ), or dapsone to prevent Pneumocystis carinii pneumonia PCP) were retrospectively examined. Two hundred sixty-two patient
- Antibody responses to two Epstein-Barr virus (EBV) nuclear antigens (EBNA-1 and EBNA-2) during EBV primary infection in children born to mothers infected with human immunodeficiency virus.
- Clin Infect Dis. 1996 Oct;23(4):806-8. Unique Identifier : AIDSLINE MED/97066367
- Pedneault L; Lapointe N; Alfieri C; Ghadirian P; Carpentier L; Samson J; Joncas J; Department of Microbiology, Hopital Sainte-Justine, Montreal, Quebec,; Canada.
- A variety of antibody response patterns to the latent Epstein-Barr nuclear antigen (EBNA) family have been described in different groups of subjects infected with Epstein-Barr virus EBV). The purpose of this study was to characterize the immune response to two EBNA proteins, EBNA-1 and EBNA-2, in a population of child
- Asymptomatic solitary pulmonary nodules due to Cryptococcus neoformans in patients infected with human immunodeficiency virus.
- Clin Infect Dis. 1996 Oct;23(4):810-2. Unique Identifier : AIDSLINE MED/97066368
- Miller KD; Mican JA; Davey RT; Laboratory of Immunoregulation, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Bethesda, Maryland; 20892, USA.
- We report the cases of three HIV-positive patients with solitary pulmonary nodules caused by Cryptococcus neoformans. Although human infection with C. neoformans occurs via the respiratory tract, isolated pulmonary infection in HIV-positive patients, in contrast with HIV-negative patients, has been thought to be relat
- Enterocytozoon bieneusi infection and diarrheal disease in patients who were not infected with human immunodeficiency virus: case report and review.
- Clin Infect Dis. 1996 Oct;23(4):816-8. Unique Identifier : AIDSLINE MED/97066370
- Wanke CA; DeGirolami P; Federman M; Department of Internal Medicine, New England Deaconess Hospital,; Harvard Medical School, Boston, Massachusetts 02215, USA.
- We describe the identification of the protozoan parasite Enterocytozoon bieneusi in the stool of a patient who was not infected with HIV but who presented with persistent diarrheal disease and severe abdominal complaints. The patient was not infected with HIV but had been noted to have a decreased CD4 cell count since
- Serum cryptococcal antigen in patients with AIDS [editorial]
- Clin Infect Dis. 1996 Oct;23(4):827-30. Unique Identifier : AIDSLINE MED/97066373
- Feldmesser M; Harris C; Reichberg S; Khan S; Casadevall A
- Disseminated Mycobacterium simiae infection in a patient with AIDS: clinical features and treatment.
- Clin Infect Dis. 1996 Oct;23(4):832-3. Unique Identifier : AIDSLINE MED/97066375
- Koeck JL; Debord T; Fabre M; Vincent V; Cavallo JD; Le Vagueresse R; Laboratoire de Biologie Clinique, Hopital d'Instruction des Armees; Dominique Larrey, Versailles, France.
- Cutaneous infection caused by Tsukamurella paurometabolum.
- Clin Infect Dis. 1996 Oct;23(4):839-40. Unique Identifier : AIDSLINE MED/97066381
- Granel F; Lozniewski A; Barbaud A; Lion C; Dailloux M; Weber M; Schmutz JL; Service de Dermatologie, Hopital Fournier, Nancy, France.
- Bilateral staphylococcal axillary lymphadenitis in a man with AIDS.
- Clin Infect Dis. 1996 Oct;23(4):840-1. Unique Identifier : AIDSLINE MED/97066382
- Kaur B; Thurn JR; Filice GA; Infectious Disease Section (111F), Veterans Affairs Medical Center,; Minneapolis, Minnesota 55417, USA.
- Disseminated infection due to multidrug-resistant Mycobacterium bovis in a patient who was seropositive for human immunodeficiency virus.
- Clin Infect Dis. 1996 Oct;23(4):841-3. Unique Identifier : AIDSLINE MED/97066383
- Schultsz C; Kuijper EJ; van Soolingen D; Prins JM; Department of Internal Medicine, Academic Medical Centre, Amsterdam,; The Netherlands.
- Rhinocerebral mucormycosis in a patient with AIDS: a complication of diabetic ketoacidosis following pentamidine therapy.
- Clin Infect Dis. 1996 Oct;23(4):845-6. Unique Identifier : AIDSLINE MED/97066386
- Abril V; Ortega E; Segarra P; Pedro F; Sabater V; Herrera A; Department of Internal Medicine, Hospital General Universitario,; Valencia, Spain.
- Isolated detection of cryptococcal polysaccharide antigen in cerebrospinal fluid samples from patients with AIDS.
- Clin Infect Dis. 1996 Oct;23(4):849-50. Unique Identifier : AIDSLINE MED/97066388
- Manfredi R; Moroni A; Mazzoni A; Nanetti A; Donati M; Mastroianni A; Coronado OV; Chiodo F; Department of Clinical and Experimental Medicine, University of; Bologna, Italy.
- 3'-Azido 3'-deoxythymidine + methotrexate as a novel antineoplastic combination in the treatment of human immunodeficiency virus-related non-Hodgkin's lymphomas.
- Blood. 1997 Jan 15;89(2):419-25. Unique Identifier : AIDSLINE MED/97156553
- Tosi P; Gherlinzoni F; Mazza P; Visani G; Coronado O; Costigliola P; Raise E; Mazzetti M; Gritti F; Chiodo F; Tura S; Istituto di Ematologia 'L. e A. Seragnoli', Policlinico S. Orsola,; Bologna, Italy.
- We have previously reported that 3 -azido 3 -deoxythymidine ( AZT ) can possess a significant antineoplastic activity when combined with drugs that disrupt de novo thymidylate synthesis, such as 5-fluorouracil and methotrexate (MTX). The aim of the pres
- A cysteine protease inhibitor prevents activation-induced T-cell apoptosis and death of peripheral blood cells from human immunodeficiency virus-infected individuals by inhibiting upregulation of Fas ligand [see comments]
- Blood. 1997 Jan 15;89(2):550-7. Unique Identifier : AIDSLINE MED/97156568
- Yang Y; Liu ZH; Ware CF; Ashwell JD; Laboratory of Immune Cell Biology, National Cancer Institute,; Bethesda, MD 20892-1152, USA.
- Activation of T-cell hybridomas, preactivated normal T cells, and peripheral blood lymphocytes (PBL) from human immunodeficiency virus (HIV)-infected individuals results in apoptosis. In the first two cases, apoptosis is caused by the upregulation of Fas ligand (FasL) and its subsequent interaction with Fas; the mecha
- Differential susceptibility to HIV-GP120-sensitized apoptosis in CD4+ T-cell clones with different T-helper phenotypes: role of CD95/CD95L interactions.
- Blood. 1997 Jan 15;89(2):558-69. Unique Identifier : AIDSLINE MED/97156569
- Accornero P; Radrizzani M; Delia D; Gerosa F; Kurrle R; Colombo MP; Division of Experimental Oncology D, Istituto Nazionale Tumori, Milan,; Italy.
- The susceptibility of Th1 and Th2 cell clones to apoptosis following HIV-gp120/CD4 cross-linking and TCR activation was investigated. We show that only Th1 clones are susceptible to HIV-gp120-sensitized apoptosis, although both types of clones express similar levels of CD4 and bind similar amounts of recombinant gp120
- Interleukin-12 (IL-12) production in whole blood cultures from human immunodeficiency virus-infected individuals studied in relation to IL-10 and prostaglandin E2 production.
- Blood. 1997 Jan 15;89(2):570-6. Unique Identifier : AIDSLINE MED/97156570
- Meyaard L; Hovenkamp E; Pakker N; van der Pouw Kraan TC; Miedema F; Department of Clinical Viro-Immunology, Central Laboratory of the; Netherlands Red Cross Blood Transfusion Service, Amsterdam, The; Netherlands.
- The role of interleukin-12 (IL-12) in Th1 cell differentiation is well established. The heterodimer p70, composed of a p40 and a p35 chain, is the biologically active form. IL-12 production by human monocytes is enhanced by interferon-gamma (IFN-gamma) and inhibited by IL-10 and prostaglandin E2 (PGE2). Peripheral blo
- CD3+, CD16+, CD56+ cells: a novel subset of T lymphocytes from patients with Balkanic nephropathy.
- Roum Arch Microbiol Immunol. 1995 Oct-Dec;54(4):255-64. Unique Identifier : AIDSLINE MED/97146216
- Drugarin D; Bona CA; Noveanu L; Schneider F; Tatu C; Department of Physiology, University of Medicine and Pharmacy; Timisoara, Romania.
- Balkanic Nephropathy (BN) is characterized by: an incidence limited to a geographic area; a familial character and a slow progressive evolution towards chronic renal failure associated with the symmetrical reduction of the kidney size. The aim of our study was to find out the immune alterations in BN pathology. The an
- Cardiomyopathy and other symptomatic heart diseases associated with HIV infection.
- Curr Opin Cardiol. 1996 May;11(3):325-31. Unique Identifier : AIDSLINE MED/96432847
- Herskowitz A; Ischemia Research and Education Foundation, San Francisco, CA 94134,; USA.
- Approximately 14 million persons worldwide are estimated to be infected with HIV-1. As more effective therapies have produced longer survival times for HIV-infected patients, new complications of late-stage HIV infection including HIV-related heart disease have emerged. The most common and life-threatening cardiovascu
- Recurrence of Kikuchi's disease with aseptic meningitis in HTLV-1 carrier [editorial; comment]
- Intern Med. 1996 Oct;35(10):753. Unique Identifier : AIDSLINE MED/97087162
- Kikuchi M
- Recurrent histiocytic necrotizing lymphadenitis (Kikuchi's disease) in an human T lymphotropic virus type I carrier [see comments]
- Intern Med. 1996 Oct;35(10):821-5. Unique Identifier : AIDSLINE MED/97087177
- Atarashi K; Yoshimura N; Nodera H; Tsukimoto K; Beppu H; Kanayama M; Department of Internal Medicine, Hiratsuka Kyosai Hospital.
- We describe a case of recurrent histiocytic necrotizing lymphadenitis (HNL) with aseptic meningitis. The patient was a 46-year-old male and a carrier of human T lymphotropic virus type I (HTLV-I). The patient had a past medical history of at least three relapses of HNL. In addition, his sister, who was also an HTLV-I
- Lectin activities of cytokines and growth factors: function and implications for pathology.
- Histol Histopathol. 1996 Oct;11(4):1101-8. Unique Identifier : AIDSLINE MED/97084307
- Zanetta JP; Scior T; Wantyghem J; Wermuth C; Aubery M; Strecker G; Michalski JC; Centre de Neurochimie du CNRS, Strasbourg, France.
- The discovery that certain cytokines have carbohydrate-binding lectin) properties opens new concepts in the understanding of their mechanism of action. The carbohydrate-recognition domain, which is localized opposite to the receptor-binding domain, makes these molecules bi-functional. The expression of the biological
- Chinese clamp down on blood products [news]
- BMJ. 1997 Jan 11;314(7074):93. Unique Identifier : AIDSLINE MED/97159118
- Tomlinson R
- Stable HIV rates hide worrying trends [news]
- BMJ. 1997 Jan 11;314(7074):94. Unique Identifier : AIDSLINE MED/97159121
- Bower H
- AIDS-related primary esophageal lymphoma.
- Abdom Imaging. 1997 Jan-Feb;22(1):11-3. Unique Identifier : AIDSLINE MED/97153435
- Sabate JM; Franquet T; Palmer J; Monill JM; Department of Diagnostic Radiology, Hospital de Sant Pau, Universidad; Autonoma de Barcelona, Avenida Sant Antoni Ma Claret 165, Barcelona; 08025, Spain.
- AIDS-related primary esophageal lymphoma should be considered in the differential diagnosis of a patient with AIDS who presents with dysphagia and a large ulcerated esophageal mass. Endoscopy is mandatory in those patients to establish a definitive diagnosis and to rule out the possibility of an infectious cause of th
- Preliminary crystallographic studies of an anti-HIV-1 protease antibody that inhibits enzyme activity.
- Protein Sci. 1996 May;5(5):966-8. Unique Identifier : AIDSLINE MED/96303819
- Lescar J; Stouracova R; Riottot MM; Chitarra V; Brynda J; Fabry M; Horejsi M; Sedlacek J; Bentley GA; Unite d'Immunologie Structurale, Institut Pasteur, Paris, France.
- F11.2.32, a monoclonal antibody directed against the HIV-1 protease, displays strong inhibitory effects toward the catalytic activity of the enzyme. The antibody cross-reacts with peptides 36-46 and 36-57 from the protease. Crystals of the Fab have been obtained both in the free state and as complexes formed with the
- Lymphocytosis of donor origin in cerebrospinal fluid, and marrow aplasia after donor leukocyte infusion for EBV-lymphoproliferative disease.
- Bone Marrow Transplant. 1996 Jul;18(1):221-4. Unique Identifier : AIDSLINE MED/96428919
- Gharpure V; Rubin L; Amlin J; Emanuel D; Schroeder W; Davidson A; Hromas R; Cornetta K; Department of Medicine, Indiana University School of Medicine,; Indianapolis, USA.
- A 29-year-old woman underwent a T cell-depleted unrelated donor transplant for CML in chronic phase. Sixty-three days after marrow infusion, the patient developed fevers and generalized lymphadenopathy. Lymph node biopsy was consistent with monoclonal EBV-associated immunoblastic lymphoma for which the patient receive
- Request for research proposals. Division of STD Prevention and Control, bureau of HIV/AIDS and STD, Laboratory Centre for Disease Control.
- Can Commun Dis Rep. 1996 Oct 15;22(20):173-4. Unique Identifier : AIDSLINE MED/97154280
- 10th anniversary of the National Reference Laboratory on AIDS in the Czech Republic.
- Cent Eur J Public Health. 1995 Nov;3(4):202-4. Unique Identifier : AIDSLINE MED/97059200
- Bruckova M; Syrucek L; Kopecka D; National Reference Laboratory on AIDS, National Institute of Public; Health, Prague, Czech Republic.
- National Reference Laboratory on AIDS (NRL AIDS) was established in the National Institute of Public Health by the Ministry of Health in the late 1985. At that time the existence of HIV/AIDS and the potencial spread of this infection/disease even in a socialistic country has been officially recognized. The main tasks
- Nasal absorption of 2',3'-didehydro-3'-deoxythymidine (D4T) and its esters in rats.
- Biol Pharm Bull. 1996 Sep;19(9):1234-7. Unique Identifier : AIDSLINE MED/97043978
- Yajima T; Hasegawa T; Juni K; Saneyoshi M; Kawaguchi T; Faculty of Pharmaceutical Sciences, Josai University, Saitama, Japan.
- Nasal absorption of 2 ,3 -didehydro-3 -deoxythymidine (D4T) and its esters (5 -acetyl D4T: C2-D4T and 5 -hemisuccinyl D4T: Suc-D4T) was investigated in rats. Bioavailability of D4T following intranasal (i.n.) administration was 98.0%, and the elimination from plasma was as rapid as that following intravenous administr
- Stargazing: 1997 NOVA Award winners.
- Hosp Health Netw. 1997 Jan 20;71(2):47-50, 52, 54-6. Unique Identifier : AIDSLINE MED/97178233
- Swan H
- Needle exchanges provide useful data [news]
- Aust Nurs J. 1996 Dec-1997 Jan;4(6):16. Unique Identifier : AIDSLINE MED/97177931
- Expression of latent membrane protein 1 in clinically isolated cases and animal models of AIDS-associated non-Hodgkin's lymphomas.
- Pathol Int. 1996 Aug;46(8):568-74. Unique Identifier : AIDSLINE MED/97048389
- Katano H; Morishita Y; Cui LX; Watanabe T; Hirai K; Mori S; Department of Pathology, University of Tokyo, Japan.
- Epstein-Barr virus (EBV)-encoded latent membrane protein 1 (LMP1) is known to be expressed in non-Hodgkin s lymphomas (NHL) occurring in immunocompromised hosts, playing crucial roles in lymphomagenesis. LMP1 expression at the microscopic level, however, was reported to be limited to some, not all, neoplastic cells in
- Epstein-Barr virus-associated post-transplant primary smooth muscle tumor of the liver: report of an autopsy case.
- Pathol Int. 1996 Aug;46(8):601-4. Unique Identifier : AIDSLINE MED/97048394
- Sadahira Y; Moriya T; Shirabe T; Matsuno T; Manabe T; Department of Pathology, Kawasaki Medical School, Kurashiki, Japan.
- Epstein-Barr (EB) virus-associated primary smooth muscle tumors have been reported in immunosuppressed young patients with acquired immunodeficiency syndrome (AIDS) and young people who have undergone liver transplantation. An autopsy case of EB virus-associated smooth muscle cell tumor in a 21 year old female who rec
- The immunologic aspects of human immunodeficiency virus infection in the gastrointestinal tract.
- Semin Gastrointest Dis. 1996 Jan;7(1):19-29. Unique Identifier : AIDSLINE MED/97059255
- Schneider T; Ullrich R; Zeitz M; Medical Clinic II, University of the Saarland, Homburg/Saar, Berlin,; Germany.
- The intestinal (in particular rectal) mucosa is an important portal of entry of human immunodeficiency virus (HIV) in homosexual men, who represent the vast majority of HIV-infected patients in Europe and North America. There are several possibilities for HIV to reach the CD4+ T cells, macrophages, and follicular dend
- Cyclophilin A complexed with a fragment of HIV-1 gag protein: insights into HIV-1 infectious activity.
- Structure. 1997 Jan 15;5(1):139-46. Unique Identifier : AIDSLINE MED/97169450
- Zhao Y; Chen Y; Schutkowski M; Fischer G; Ke H; Department of Biochemistry and Biophysics, School of Medicine, The; University of North Carolina, Chapel Hill, NC 27599, USA.
- BACKGROUND: Cyclophilin A (CyPA), a receptor of the immunosuppressive drug cyclosporin A, catalyzes the cis-trans isomerization of peptidyl-prolyl bonds and is required for the infectious activity of human immunodeficiency virus type 1 HIV-1). The crystal structure of CyPA complexed with a fragment of the HIV-1 gag pr
- Role REVersal: understanding how RRE RNA binds its peptide ligand.
- Structure. 1997 Jan 15;5(1):7-11. Unique Identifier : AIDSLINE MED/97169439
- Grate D; Wilson C; Department of Biology, University of California at Santa Cruz, 1156; High Street, Santa Cruz, CA 95064, USA. grate@biology.ucsc.edu
- The structure of a complex between the HIV Revresponsive element RRE) RNA and a fragment of the Rev protein has recently been determined by NMR. Together with previous studies of the Tat-TAR complex, these results show how RNA elements with considerable tertiary structure are able to play a more active role in directi
- HIV-1: is Nef a PAK animal?
- Curr Biol. 1996 Dec 1;6(12):1557-9. Unique Identifier : AIDSLINE MED/97148179
- Cullen BR; Howard Hughes Medical Institute, Durham, North Carolina, USA.
- HIV-1 Nef is clearly essential for efficient viral replication in vivo, but it has been difficult to determine why. Recent evidence that Nef specifically activates a PAK-dependent signalling cascade may be the first step in defining the mechanism of action of this enigmatic viral protein.
- CDC42 and Rac1 are implicated in the activation of the Nef-associated kinase and replication of HIV-1.
- Curr Biol. 1996 Dec 1;6(12):1677-84. Unique Identifier : AIDSLINE MED/97148201
- Lu X; Wu X; Plemenitas A; Yu H; Sawai ET; Abo A; Peterlin BM; Howard Hughes Medical Institute, University of California at San; Francisco, California, USA.
- BACKGROUND: The negative factor (Nef) of human and simian immunodeficiency viruses (HIV-1, HIV-2 and SIV) is required for high levels of viremia and progression to AIDS. Additionally, Nef leads to cellular activation, increased viral infectivity and decreased expression of CD4 on the cell surface. Previously, we and o
- Unusual presentation of a tuberculous peritonitis in a patient with concomitant AIDS and liver cirrhosis.
- Eur J Gastroenterol Hepatol. 1996 Oct;8(10):1021-2. Unique Identifier : AIDSLINE MED/97084227
- Turner L; Dupont C; Lesur G; Barthod F; Moreau D; Rouveix E; Dorra M; Department of Medicine, Hopital Ambroise Pare, Boulogne, France.
- We report a case of tuberculous peritonitis in a patient with concomitant HIV infection and liver cirrhosis. A 50-year-old man with viral B and delta liver cirrhosis and AIDS was diagnosed with spontaneous Escherichia coli peritonitis and successfully treated with beta-lactamins. Three months later, ascites reappeared
- New trends in the drug therapy of localized and disseminated Mycobacterium avium complex infection [see comments]
- Am J Health Syst Pharm. 1996 Nov 1;53(21):2585-90. Unique Identifier : AIDSLINE MED/97070461
- Sesin GP; Manzi SF; Pacheco R; Charlton Memorial Hospital, Fall River, MA 02720, USA.
- Recent advances in the drug therapy of localized and disseminated infection with Mycobacterium avium complex (MAC) are reviewed. MAC infection is the most commonly reported bacterial infection in patients with AIDS, and the frequency of this infection in patients negative for the human immunodeficiency virus (HIV) is
- HLA allele selection for designing peptide vaccines.
- Genet Anal. 1996 Sep;13(3):81-6. Unique Identifier : AIDSLINE MED/97085921
- Gulukota K; DeLisi C; Department of Biomedical Engineering, Boston University, MA 02215,; USA. gulu@bu.edu
- A central problem in developing vaccines against rapidly evolving viruses such as HIV and Influenza is the mutability of their antigens. In principle, the problem can be mitigated by using peptides from conserved portions of viral proteins. However, because cytotoxic T lymphocytes (CTLs), which such vaccines would sti
- Patients with HIV infection and end-stage renal disease.
- Adv Ren Replace Ther. 1996 Oct;3(4):287-92. Unique Identifier : AIDSLINE MED/97071845
- Schoenfeld P; Rodriguez R; Mendelson M; University of California Renal Center, San Francisco, USA.
- There has been a steady increase in the number of dialysis patients with human immunodeficiency viral (HIV) infection. HIV-associated nephropathy (HIVAN) is the most common cause of end-stage renal disease in this patient population. Although the major potential category of risk of HIV transmission is from the dialysi
- HIV infection: challenges for dialysis personnel.
- Adv Ren Replace Ther. 1996 Oct;3(4):293-7. Unique Identifier : AIDSLINE MED/97071846
- Bradley-Springer L; New Mexico AIDS Education and Training Center, Albuquerque 87131, USA.
- Patients with human immunodeficiency viral (HIV) infection who also require dialysis present a complex constellation of challenges for dialysis personnel. The major challenges that health care providers (HCPs) face when working with HIV-infected patients are related to overcoming personal fears and to adapting to HIV-
- Disposal of dialysate in HIV-positive patients: an update.
- Adv Ren Replace Ther. 1996 Oct;3(4):298-301. Unique Identifier : AIDSLINE MED/97071847
- Scheel PJ Jr; Malan M; Department of Medicine Johns Hopkins Medical Institutions, Baltimore,; MD, USA.
- One of the concerns with the use of peritoneal dialysis in human immunodeficiency virus (HIV)-positive patients is disposal of the peritoneal effluents. This article reviews survival characteristics of HIV in dialysate effluents and current disinfectant strategies.
- An evaluation of dipstick-dot immunoassay in the detection of antibodies to HIV-1 and 2 in Zimbabwe.
- Trop Med Int Health. 1997 Jan;2(1):83-8. Unique Identifier : AIDSLINE MED/97171032
- Ray CS; Mason PR; Smith H; Rogers L; Tobaiwa O; Katzenstein DA; Zimbabwe AIDS Prevention Project, University of Zimbabwe, Harare,; Zimbabwe.
- There is a need, in many developing countries, for simple and inexpensive HIV serology tests for use at the district level of health care. The Programme for Appropriate Technology in Health has developed a simple dipstick ELISA to detect antibodies to HIV-1 and 2, at a cost considerably lower than current ELISAs, whic
- HIV postexposure prophylaxis: new recommendations [see comments]
- Can Med Assoc J. 1997 Jan 15;156(2):233-4. Unique Identifier : AIDSLINE MED/97164966
- Patrick DM; British Columbia Centre for Disease Control Vancouver, BC.
- Kit helps physicians, women work together to weigh HRT risks, benefits.
- Can Med Assoc J. 1997 Jan 15;156(2):248-50. Unique Identifier : AIDSLINE MED/97164971
- Robinson A
- The Ottawa Health Decision Centre is developing a line of decision AIDS to make it easier for physicians to discuss potential therapies with patients. The first kit, Making choices: hormones after menopause, helps women weigh the risks and benefits of hormone replacement therapy.
- Anti-HTLV-1 antibody positive cutaneous T-cell lymphoma.
- Cancer. 1997 Jan 15;79(2):269-74. Unique Identifier : AIDSLINE MED/97163265
- Kikuchi A; Ohata Y; Matsumoto H; Sugiura M; Nishikawa T; Department of Dermatology, Keio University School of Medicine, Tokyo,; Japan.
- BACKGROUND: Adult T-cell leukemia/lymphoma (ATLL) is a neoplasm of the mature helper T-lymphocyte. Human T-lymphotropic virus type 1 (HTLV-1) has been shown to be the cause of this neoplasm. Recently, however, the HTLV-1 genome has been found in some patients with cutaneous T-cell lymphoma (CTCL), which suggests a cau
- Denver HIV/AIDS demonstration program--project SNAPP is a winner!
- Colo Nurse. 1996 Dec;96(4):33. Unique Identifier : AIDSLINE MED/97177954
- Moorhouse M
- Oxidative stress in blood of HIV infected patients.
- Clin Chim Acta. 1996 Nov 29;255(2):107-17. Unique Identifier : AIDSLINE MED/97092089
- Repetto M; Reides C; Gomez Carretero ML; Costa M; Griemberg G; Llesuy S; National Laboratory of Free Radical Biology, Catedra de Quimica; General e Inorganica, Facultad de Farmacia y Bioquimica, Universidad; de Buenos Aires, Argentina.
- The oxidative stress in human erythrocytes was studied in asymptomatic and symptomatic patients infected by the human immunodeficiency virus (HIV), and patients with the acquired immunodeficiency syndrome (AIDS). tert-Butyl hydroperoxide initiated chemiluminescence, superoxide dismutase and catalase activities, and to
- Escape of HIV-1 is associated with lack of V3 domain-specific antibodies in vivo.
- Clin Exp Immunol. 1997 Jan;107(1):15-20. Unique Identifier : AIDSLINE MED/97163431
- Schreiber M; Muller H; Wachsmuth C; Laue T; Hufert FT; Van Laer MD; Schmitz H; Medical Microbiology Section, Department of Virology, Bernhard Nocht; Institute for Tropical Medicine, Hamburg, Germany.
- This study was performed to analyse correlates of viral escape in AIDS patients. Peripheral blood mononuclear cells (PBMC) from HIV- donors were inoculated with AIDS patients serum to detect neutralization-resistant cell-free virus. Infectious virus was detected by polymerase chain reaction (PCR) and analysed by sequ
- Relevance of local Th2-type cytokine mRNA expression in immunocompetent infiltrates in inflamed gingival tissue to periodontal diseases.
- Clin Exp Immunol. 1997 Jan;107(1):166-74. Unique Identifier : AIDSLINE MED/97163452
- Tokoro Y; Matsuki Y; Yamamoto T; Suzuki T; Hara K; Department of Periodontology, Niigata University School of Dentistry,; Japan.
- It has been suggested that the types of inflammatory round cell infiltrates and the divergence in the cytokine production profile by macrophages and helper T cells regulate the course of infectious or inflammatory diseases, including periodontitis and gingivitis. We examined the expression of IL-1alpha, IL-1beta,
- T cell receptor (TCR) BV gene repertoires and clonal expansions of CD4 cells in patients with HIV infections.
- Clin Exp Immunol. 1997 Jan;107(1):21-30. Unique Identifier : AIDSLINE MED/97163432
- Roglic M; Macphee RD; Duncan SR; Sattler FR; Theofilopoulos AN; Department of Immunology, The Scripps Research Institute, La Jolla, CA; 92037, USA.
- Despite extensive investigation, the pathogenesis of T cell depletions that characterize AIDS has not been elucidated. To study this process further, we evaluated T cell antigen receptor beta-chain variable gene (TCRBV) repertoires in peripheral blood lymphocytes (PBL) of 23 HIV-infected patients. Expression levels of
- Progression of HIV disease is associated with increased expression of Fc gammaRI and CR1 on alveolar macrophages.
- Clin Exp Immunol. 1997 Jan;107(1):31-6. Unique Identifier : AIDSLINE MED/97163433
- Gilbody J; Lipman MC; Johnson MA; Atkins M; Poulter LW; Department of Clinical Immunology, Royal Free Hospital and School of; Medicine, London, UK.
- The expression of receptors for complement and the Fc region of immunoglobulin by alveolar macrophages (AM) constitutes a valuable aid to effector function of these cells. However, during HIV infection such expression may also act to increase binding of immune complexes, thus facilitating viral infection of these cell
- Modulation of lymphocyte and monocyte activity after intravenous immunoglobulin administration in vivo.
- Clin Exp Immunol. 1997 Jan;107(1):50-6. Unique Identifier : AIDSLINE MED/97163436
- Aukrust P; Muller F; Nordoy I; Haug CJ; Froland SS; Medical Department A and Research Institute for Internal Medicine,; University of Oslo, The National Hospital, Rikshospitalet, Norway.
- In 12 patients with primary hypogammaglobulinaemia we investigated the in vivo effect of one bolus injection (400 mg/kg) of intravenous immunoglobulin (IVIG) on lymphocyte subsets and monocytes in peripheral blood, on plasma levels of soluble factors reflecting monocyte and lymphocyte activity and on lymphocyte prolif
- Comparative brain pathology of HIV-seronegative and HIV-infected drug addicts.
- Clin Neuropathol. 1996 Nov-Dec;15(6):324-9. Unique Identifier : AIDSLINE MED/97092113
- Makrigeorgi-Butera M; Hagel C; Laas R; Puschel K; Stavrou D; Department of Neuropathology, University of Hamburg, Germany.
- Early stages of infection with human immunodeficiency virus (HIV) were studied in HIV-seropositive drug addicts. Since heroin users are immunocompromized even in the absence of HIV infection, the aim of the present study was to compare the morphological alterations present in HIV-seronegative and HIV-seropositive drug
- Vascular changes in the cerebral cortex in HIV-1 infection: I. A morphometric investigation by light and electron microscopy.
- Clin Neuropathol. 1996 Nov-Dec;15(6):361-6. Unique Identifier : AIDSLINE MED/97092120
- Weis S; Haug H; Budka H; Institute of Neuropathology, Ludwig-Maximilians-University, Munich,; Germany.
- The microvasculature of the cerebral cortex in AIDS brains was investigated by means of stereology at the light and electron microscopic levels. Stereologic parameters for microvessels were determined in formalin-fixed autopsy tissue of 24 AIDS patients and of 35 age- and sex-matched controls. At the light microscopic
- A pooled analysis of CD4 response to zidovudine and zalcitabine treatment in patients with AIDS and AIDS-related complex.
- Clin Pharmacol Ther. 1997 Jan;61(1):70-82. Unique Identifier : AIDSLINE MED/97176636
- Gries JM; Troconiz IF; Verotta D; Jacobson M; Sheiner LB; Department of Biopharmaceutical Sciences, School of Pharmacy,; University of California, San Francisco 94143-0446, USA.
- INTRODUCTION: This article reports a meta-analysis focused on the efficacy of zalcitabine and zidovudine alone or in combination as reported by three AIDS Clinical Trial Group trials. We analyzed the log CD4 count (LCD4) response to therapy up to 1 year after the beginning of therapy. One of the purposes of this artic
- Dangerousness and dentistry: an explanation of dentists' reactions and responses to the treatment of HIV-seropositive patients.
- Community Dent Oral Epidemiol. 1996 Oct;24(5):341-5. Unique Identifier : AIDSLINE MED/97112541
- Gibson BJ; Freeman R; Dental Public Health Research Group, School of Clinical Dentistry,; Queen's University of Belfast, N. Ireland.
- Factors which influence health professional s willingness to treat HIV seropositive patients have been explained in terms of the concept of dangerousness. Can this concept be used as a vehicle to explain dentists responses? All dentists currently in practice in Northern
- Persistent activation of CD8+ T-cells characterizes prediabetic twins.
- Diabetes Care. 1996 Nov;19(11):1177-84. Unique Identifier : AIDSLINE MED/97064826
- Peakman M; Leslie RD; Alviggi L; Hawa M; Vergani D; Department of Immunology, King's College School of Medicine and; Dentistry, London, U.K.
- OBJECTIVE: Elevated circulating levels of activated CD3+ T-cells are characteristic of type I diabetes at diagnosis, and activated CD8+ (cytotoxic/suppressor) T-cells predominate in the islet infiltrate. The aim of this study was to examine the peripheral blood of prediabetic and nondiabetic identical twins of patient
- Substance abuse treatment entry, retention and effectiveness: out-of-treatment opiate injection drug users.
- Drug Alcohol Depend. 1996 Sep;42(1):11-20. Unique Identifier : AIDSLINE MED/97044328
- Booth RE; Crowley TJ; Zhang Y; Department of Psychiatry, School of Medicine, University of Colorado; Health Sciences Center, Denver 80211, USA.
- This study was designed to assess the effect of client characteristics and community interventions on treatment entry and retention, and to evaluate the relative effectiveness of treatment, compared to other interventions, in reducing drug use and crime among out-of-treatment opiate injectors. Subjects (N = 2973) from
- Crack cocaine smokers who turn to drug injection: characteristics, factors associated with injection, and implications for HIV transmission. The Multicenter Crack Cocaine and HIV Infection Study Team.
- Drug Alcohol Depend. 1996 Oct;42(2):85-92. Unique Identifier : AIDSLINE MED/97044336
- Irwin KL; Edlin BR; Faruque S; McCoy HV; Word C; Serrano Y; Inciardi J; Bowser B; Holmberg SD; Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
- A survey of 1220 street-recruited crack cocaine smokers revealed that crack smokers may turn to drug injection to ease crack withdrawal. Crack smokers who later injected tended to smoke crack more heavily and for longer periods than those who did not inject. The initiation of injection was significantly associated wit
- Cytomegalovirus ileocolitis: different manifestations of the same illness in the terminal ileum and colon.
- Endoscopy. 1996 Oct;28(8):729. Unique Identifier : AIDSLINE MED/97088160
- Sebastian JJ; Uribarrena R; Gastroenterology Dept., Miguel Servet Hospital, Zaragoza, Spain.
- Statistical methods for the blood beryllium lymphocyte proliferation test.
- Environ Health Perspect. 1996 Oct;104 Suppl 5:957-68. Unique Identifier : AIDSLINE MED/97087013
- Frome EL; Smith MH; Littlefield LG; Neubert RL; Colyer SP; Computer Science and Mathematics Division, Oak Ridge National; Laboratory, Tennessee 37831-6367, USA. fromeel@ornl.gov
- The blood beryllium lymphocyte proliferation test (BeLPT) is a modification of the standard lymphocyte proliferation test that is used to identify persons who may have chronic beryllium disease. A major problem in the interpretation of BeLPT test results is outlying data values among the replicate well counts approxim
- Prospective evaluation of fever of unknown origin in patients infected with the human immunodeficiency virus. Grupo Andaluz para el Estudio de las Enfermedades Infecciosas.
- Eur J Clin Microbiol Infect Dis. 1996 Sep;15(9):705-11. Unique Identifier : AIDSLINE MED/97081324
- Lozano F; Torre-Cisneros J; Bascunana A; Polo J; Viciana P; Garcia-Ordonez MA; Hernandez-Quero J; Marquez M; Vergara A; Diez F; Pujol E; Torres-Tortosa M; Pasquau J; Hernandez-Burruezo JJ; Suarez I; Infectious Diseases Section, Hospital Universitario de Valme, Seville,; Spain.
- The aim of this study was to determine the frequency and aetiology of fever of unknown origin (FUO) in patients infected with the human immunodeficiency virus (HIV), to assess the value of the tests used in its diagnosis, and to evaluate possible models of diagnosis for the causes found most frequently. One hundred tw
- Isolation of Bartonella quintana from an HIV-positive patient with bacillary angiomatosis.
- Eur J Clin Microbiol Infect Dis. 1996 Sep;15(9):736-41. Unique Identifier : AIDSLINE MED/97081329
- Schmidt HU; Kaliebe T; Poppinger J; Buhler C; Sander A; Institut fur Medizinische Mikrobiologie, Krankenhaus; Munchen-Schwabing, Germany.
- Bartonella quintana was grown from a lysis-centrifugation blood culture of an HIV-positive man who presented with lesions of bacillary angiomatosis in skin and bones. The isolate was identified by sodium dodecylsulfate-polyacrylamide gel electrophoresis, 16S rRNA gene sequenc
- Sexual behaviour and multiple infections in drug abusers.
- Eur J Epidemiol. 1996 Oct;12(5):429-35. Unique Identifier : AIDSLINE MED/97061271
- Coppola RC; Masia G; di Martino ML; Carboni G; Muggianu E; Piro R; Manconi PE; Department of Hygiene and Public Health, University of Cagliari,; Italy.
- We have studied the prevalence and the serological profile of HBV, HCV, HDV and HIV infections in 137 Italian subjects addicted to the intravenous use of heroine and correlated the virological findings with sexual behaviour. HBV and HCV viremia were also measured in 114 patients. Anti-HCV was detected in 81% of the ad
- Vertical transmission of hepatitis C virus: an epidemiological study on 2,980 pregnant women in Italy.
- Eur J Epidemiol. 1996 Oct;12(5):443-7. Unique Identifier : AIDSLINE MED/97061273
- Sabatino G; Ramenghi LA; di Marzio M; Pizzigallo E; Department of Pediatrics-Neonatal Intensive Care Unit, G. D' Annunzio; University, Chieti, Italy.
- The risk of mother-to-infant transmission of hepatitis C virus HCV) varies according to the population studied and the tests used. Aim of the current study was to investigate HCV vertical transmission rate in children born to 30 HCV positive/HIV negative pregnant women in Italy . We
- Direct activation of protein phosphatase-2A0 by HIV-1 encoded protein complex NCp7:vpr.
- FEBS Lett. 1997 Jan 20;401(2-3):197-201. Unique Identifier : AIDSLINE MED/97165993
- Tung HY; De Rocquigny H; Zhao LJ; Cayla X; Roques BP; Ozon R; Laboratoire de Physiologie de la Reproduction, CNRS URA 1449, INRA,; Universite Pierre et Marie Curie, Paris, France.; ltung@hall.snv.jussieu.fr
- The effects of HIV-1 encoded proteins NCp7, vpr and NCp7:vpr complex on the activity of protein phosphatase-2A0 have been tested. We report that NCp7 is an activator of protein phosphatase-2A0 and that vpr activated protein phosphatase-2A0 only slightly. We also report that NCp7 and vpr form a tight complex which beco
- Development of a novel drug-delivery system using bacteriophage MS2 capsids.
- Biochem Soc Trans. 1996 Aug;24(3):413S. Unique Identifier : AIDSLINE MED/97033210
- Wu M; Brown WL; Hill HR; Stockley PG; Department of Biology, University of Leeds, UK.
- [Serum cardiolipin antibodies in patients with alcoholic cirrhosis]
- Gastroenterol Clin Biol. 1996;20(10):736-42. Unique Identifier : AIDSLINE MED/97145500
- Gervais A; Czernichow B; Grunebaum L; Wiesel ML; Auperin A; Rivalland D; Gabanyi J; Goldstein L; Cazenave JP; Doffoel M; Service d'Hepato-Gastroenterologie, Hopital Civil, Strasbourg.
- OBJECTIVE: Although portal obstruction is a complication in cirrhosis which is usually associated with hepatocellular carcinoma, its precise neoplastic or thrombotic nature is not easy to determine. Serum antiphospholipid antibodies could be involved in thrombosis-related portal obstruction. PATIENTS AND METHODS: The
- Outpatient therapeutic ERCP: a series of 262 consecutive cases.
- Gastrointest Endosc. 1996 Oct;44(4):443-9. Unique Identifier : AIDSLINE MED/97061336
- Mehta SN; Pavone E; Barkun AN; Montreal General Hospital, Quebec, Canada.
- BACKGROUND: Because of possible complications, it has been common practice to admit most if not all patients undergoing therapeutic ERCP. Therefore, little descriptive data exist on the safety of outpatient therapeutic ERCP. METHODS: We assessed 262 consecutive ERCPs in 209 patients undergoing outpatient therapeutic E
- T-cell lymphoma in Hashimoto's thyroiditis.
- Histopathology. 1996 Nov;29(5):455-9. Unique Identifier : AIDSLINE MED/97109211
- Abdul-Rahman ZH; Gogas HJ; Tooze JA; Anderson B; Mansi J; Sacks NP; Finlayson CJ; Department of Histopathology, St George's Hospital, London, UK.
- An elderly Caucasian woman with a 2-year-history of hypothyroidism, treated with thyroxine, presented with a rapidly growing mass in the thyroid. The morphological and immunological features of this thyroid tumour were those of a peripheral T-cell lymphoma with an immunophenotype commonly associated with HTLV-1 positi
- The potential roles of endogenous retroviruses in autoimmunity.
- Immunol Rev. 1996 Aug;152:193-236. Unique Identifier : AIDSLINE MED/97084330
- Nakagawa K; Harrison LC; Burnet Clinical Research Unit, Walter and Eliza Hall Institute of; Medical Research, Royal Melbourne Hospital, Parkville, Australia.
- Endogenous retroviruses (ERVs) are estimated to comprise up to 1% of human DNA. While the genome of many ERVs is interrupted by termination codons, deletions or frame shift mutations, some ERVs are transcriptionally active and recent studies reveal protein expression or particle formation by human ERVs. ERVs have been
- Flavivirus-induced up-regulation of MHC class I antigens; implications for the induction of CD8+ T-cell-mediated autoimmunity.
- Immunol Rev. 1996 Aug;152:5-19. Unique Identifier : AIDSLINE MED/97084321
- Lobigs M; Blanden RV; Mullbacher A; Division of Immunology and Cell Biology, John Curtin School of Medical; Research, Australian National University, Canberra, Australia.
- Infection of a wide variety of cells of human, mouse and other species origin by flaviviruses such as WNV, YF, Den, MVE, KUN and JE, increases the cell-surface expression of MHC class I. This MHC class I up-regulation is not due to increased MHC class I synthesis per se, but the result of increased peptide availabili
- A role for B cells in resistance to Cryptococcus neoformans in mice.
- Infect Immun. 1997 Feb;65(2):525-30. Unique Identifier : AIDSLINE MED/97162321
- Aguirre KM; Johnson LL; Trudeau Institute, Saranac Lake, New York 12983, USA.
- The role of B cells in immunity to Cryptococcus neoformans was investigated. Genetically targeted, B-cell-deficient mice (mu Mt) examined at various times after intravenous infection with C. neoformans 184 had lung and brain yeast burdens that were equivalent to tissue burdens in control B-cell-sufficient mice. Both B
- Th1 and Th2 cytokines in mice with invasive aspergillosis.
- Infect Immun. 1997 Feb;65(2):564-70. Unique Identifier : AIDSLINE MED/97162327
- Cenci E; Perito S; Enssle KH; Mosci P; Latge JP; Romani L; Bistoni F; Microbiology Section, Department of Experimental Medicine and; Biochemical Sciences, University of Perugia, Italy.
- With a murine model of invasive aspergillosis we investigated cytokine production by CD4+ T helper cells and the effects of cytokine administration or neutralization on the course and outcome of infection. Patterns of susceptibility and resistance to infection were obtained with different strains of mice injected with
- Oral carriage of Candida albicans in murine AIDS.
- Infect Immun. 1997 Feb;65(2):661-7. Unique Identifier : AIDSLINE MED/97162341
- Deslauriers N; Cote L; Montplaisir S; de Repentigny L; Faculty of Dental Medicine, Laval University, Quebec, Canada.
- Oral candidiasis is a common fungal infection in patients infected with the human immunodeficiency virus (HIV). Although rare at the time of primary HIV infection, it is frequently found throughout the asymptomatic phase and is predictive of progressive immunodeficiency. However, the precise immune defect which result
- Induction of cytotoxic T-cell responses against culture filtrate antigens in Mycobacterium bovis bacillus Calmette-Guerin-infected mice.
- Infect Immun. 1997 Feb;65(2):676-84. Unique Identifier : AIDSLINE MED/97162343
- Denis O; Lozes E; Huygen K; Laboratory of Mycobacterial Immunology, Pasteur Institute of Brussels,; Belgium.
- CD8+ T cells are essential for protection against mycobacteria, as is clearly demonstrated by the fatal outcome of experimental infection of beta-2 microglobulin knockout mice. However, the mechanisms and antigens (Ags) leading to CD8+ T-cell activation and regulation have been poorly characterized. Here we show that,
- Herpes simplex virus type 2 in Brazil: seroepidemiologic survey.
- Int J Dermatol. 1996 Nov;35(11):794-6. Unique Identifier : AIDSLINE MED/97072984
- Da Rosa-Santos OL; Goncalves Da Silva A; Pereira AC Jr; Department of Medical Clinics (Dermatology), Clementino Fraga Filho; University Hospital, Rio de Janeiro, Brazil.
- BACKGROUND: The incidence of genital herpes is increasing worldwide. Herpes simplex virus type 2 (HSV-2) is the most common cause of genital ulcerations among the sexually transmitted diseases (STDS). In order to investigate the sexual transmission of genital herpes infection in
- Nodular Kaposi's sarcoma as a presenting feature of HIV infection.
- Int J Dermatol. 1996 Nov;35(11):813-5. Unique Identifier : AIDSLINE MED/97072990
- Gonzalez-Martinez R; Marin-Bertolin S; Martinez-Escribano J; Amorrortu-Velayos J; Department of Plastic and Reconstructive Surgery, University General; Hospital, Valencia, Spain.
- Kaposi's sarcoma and sarcoidosis coexisting in lesions of HIV-seronegative patient.
- Int J Dermatol. 1996 Nov;35(11):824-6. Unique Identifier : AIDSLINE MED/97072995
- Dessoukey MW; Dayem HA; Omer MF; Department of Dermatology, Al-Jazeira Hospital, Abu-Dhabi, United Arab; Emirates.
- Advanced epidemic Kaposi's sarcoma: treatment with bleomycin or combination of doxorubicin, bleomycin, and vincristine.
- Int J Dermatol. 1996 Nov;35(11):831-3. Unique Identifier : AIDSLINE MED/97072998
- Hernandez DE; Perez JR; Department of Medicine, Vargas Medical School, Hospital Vargas,; Universidad Central de Venezuela, Caracas, Venezuela.
- BACKGROUND: Systemic chemotherapy is a treatment modality in the management of epidemic Kaposi s sarcoma (EKS). We conducted a prospective trial to compare bleomycin as a single agent with a regimen of low-dose doxorubicin, bleomycin, and vincristine (ABV) in patients with advanced EKS. METHODS: Twenty-four homosexual
- Antioxidant vitamins and immunodeficiency.
- Int J Vitam Nutr Res. 1996;66(2):141-5. Unique Identifier : AIDSLINE MED/97000959
- Mastroiacovo P; Ajassa C; Berardelli G; Bruni R; Catania N; Fidanza A; Pace V; Zanzoglous S; Institute of General Physiology, La Sapienza University, Rome, Italy.
- On the plasma of 20 children from 1 to 6 years old with HIV infection, the following analyses were carried out: vitamin assays (vitamin E and beta-carotene), hematochemical assays, and immunoassays. From the body of our results it emerged that in the seropositive children considered, in addition to the already well-kn
- New therapies for cytomegalovirus retinitis.
- Int Ophthalmol Clin. 1996 Spring;36(2):1-9. Unique Identifier : AIDSLINE MED/97107904
- Schwartz DM; Department of Ophthalmology, University of California, San Francisco; 94143, USA.
- A phase II study of weekly oral methotrexate and zidovudine (AZT) in advanced adenocarcinoma of the pancreas and hepatocellular carcinoma.
- Invest New Drugs. 1996;14(2):207-12. Unique Identifier : AIDSLINE MED/97070916
- Miller KD; Loehrer PJ; Gonin R; Weber G; Ansari R; Pletcher W; McClean J; Spiridonidis CH; Mortimer J; Department of Medicine, Indiana University Medical Center,; Indianapolis, USA.
- From January 1992 through May 1993, 31 patients with adenocarcinoma of the pancreas or hepatocellular carcinoma were treated with weekly oral methotrexate (7.5 mg/M2 every 6 hours for 6 doses) and continuous oral AZT (200 mg four times daily). Patient
- Pharmacokinetic profile of Mitoguazone (MGBG) in patients with AIDS related non-Hodgkin's lymphoma.
- Invest New Drugs. 1996;14(2):227-34. Unique Identifier : AIDSLINE MED/97070920
- Rizzo J; Levine AM; Weiss GR; Pearce T; Kraynak M; Mueck R; Smith S; Von Hoff DD; Kuhn JG; Cancer Therapy and Research Center, San Antonio, TX, 78229, USA.
- Mitoguazone is a unique chemotherapeutic agent whose activity is believed to result primarily from the competitive inhibition of S-adenosyl-methionine decarboxylase leading to a disruption in polyamine biosynthesis. Initial clinical trials demonstrated that the dose-limiting toxicities (mucositis and myelosuppression)
- [Plasmapheresis and immunopathogenetic aspects of toxic epidermal necrolysis]
- Hautarzt. 1996 Oct;47(10):749-53. Unique Identifier : AIDSLINE MED/97095312
- Hermes B; Haas N; Henz BM; Hautklinik, Virchow-Klinikum, Humboldt-Universitat zu Berlin.
- Drug-induced toxic epidermal necrolysis (TEN) is a rare but frequently lethal disease of the skin and mucosa of unknown etiology. Toxic metabolic and immunologic products in the serum have been discussed as possible causes. For this reason we have performed plasmapheresis on these patients for many years. Results rega
- [HIV-associated skin diseases. 1: Follow-up and epidemiology of HIV infection, pathogen-induced HIV-associated dermatoses]
- Hautarzt. 1996 Oct;47(10):795-813. Unique Identifier : AIDSLINE MED/97095322
- Ramsauer J; Plettenberg A; Meigel W; Abteilung fur Dermatologie, Allgemeines Krankenhaus St. Georg,; Hamburg.
- In-vitro activity of macrolides alone and in combination with artemisin, atovaquone, dapsone, minocycline or pyrimethamine against Cryptosporidium parvum.
- J Antimicrob Chemother. 1996 Sep;38(3):399-408. Unique Identifier : AIDSLINE MED/97044644
- Giacometti A; Cirioni O; Scalise G; Institute of Infectious Diseases and Public Health, University of; Ancona, Italy.
- The anticryptosporidial activity of four macrolides alone and in combination with other antimicrobial agents was investigated against ten clinical isolates of Cryptosporidium parvum recovered from stools of AIDS patients. The susceptibility tests were performed by inoculation of the protozoa on to cell monolayers and
- Multi-drug resistant non-typhi salmonellae in Kenya.
- J Antimicrob Chemother. 1996 Sep;38(3):425-34. Unique Identifier : AIDSLINE MED/97044646
- Kariuki S; Gilks C; Corkill J; Kimari J; Benea A; Waiyaki P; Hart CA; Department of Medical Microbiology, School of Tropical Medicine,; University of Liverpool, UK.
- Two methods of plasmid characterization, restriction digest patterns and incompatibility grouping, were used to study self-transmissible multi-drug resistance among non-typhi salmonellae (NTS). Resistance to ampicillin and other commonly applied beta-lactams was evaluated by iso-electric focusing and disc inactivation
- Comparative activity of azithromycin against clinical isolates of mycobacteria.
- J Antimicrob Chemother. 1996 Sep;38(3):539-42. Unique Identifier : AIDSLINE MED/97044656
- Watt B; Rayner A; Harris G; Scottish Mycobacteria Reference Laboratory, City Hospital, Edinburgh,; UK.
- Azithromycin exhibited in-vitro activity against 20 clinical isolates of Mycobacterium avium complex for which the MIC90 was 32 mg/L and 22 clinical isolates of other mycobacteria but showed no activity against 20 isolates of Mycobacterium tuberculosis MIC90 > 128 mg/L) nor against the single isolate of Mycobacterium
- Preferential binding of poly(A)-binding protein 1 to an inhibitory RNA element in the human immunodeficiency virus type 1 gag mRNA.
- J Biol Chem. 1997 Jan 24;272(4):2307-11. Unique Identifier : AIDSLINE MED/97153004
- Afonina E; Neumann M; Pavlakis GN; Human Retrovirus Section, ABL-Basic Research Program, NCI-FCRDC,; Frederick, Maryland 21702-1201, USA.
- Human immunodeficiency virus type 1 (HIV-1) mRNAs encoding structural proteins contain multiple inhibitory/instability elements (INS), which decrease the efficiency of viral protein expression. We have previously identified a strong INS element INS-1) within the p17(gag) coding region. Here we show that poly(A)-bindin
- Susceptibility testing of fungi: current status of correlation of in vitro data with clinical outcome.
- J Clin Microbiol. 1996 Mar;34(3):489-95. Unique Identifier : AIDSLINE MED/97060079
- Ghannoum MA; Rex JH; Galgiani JN; Division of Infectious Diseases, Department of Internal Medicine,; Harbor-University of California, Los Angeles, USA. ghannoum@humc.edu
- In summary, it is clear that in vitro susceptibility testing can predict outcome in selected clinical situations. The clearest data are from the fluconazole-treated AIDS patients with oropharyngeal candidiasis. In this setting, the homogeneity of the underlying immune defect, combined with the ease of identification a
- Rapid diagnosis of Mycobacterium tuberculosis bacteremia by PCR.
- J Clin Microbiol. 1996 Mar;34(3):512-5. Unique Identifier : AIDSLINE MED/97060083
- Folgueira L; Delgado R; Palenque E; Aguado JM; Noriega AR; Department of Clinical Microbiology, Hospital Doce de Octubre, Madrid,; Spain.
- A method based on DNA amplification and hybridization has been used for the rapid detection of Mycobacterium tuberculosis in blood samples from 38 hospitalized patients (15 human immunodeficiency virus [HIV] positive and 23 HIV negative) in whom localized or disseminated forms of tuberculosis were suspected. In 32 of
- Quantitative light microscopic detection of Enterocytozoon bieneusi in stool specimens: a longitudinal study of human immunodeficiency virus-infected microsporidiosis patients.
- J Clin Microbiol. 1996 Mar;34(3):520-3. Unique Identifier : AIDSLINE MED/97060085
- Clarridge JE 3rd; Karkhanis S; Rabeneck L; Marino B; Foote LW; Veterans Affairs Medical Center, Baylor College of Medicine, Houston,; Texas 77030, USA.
- The clinical course of microsporidiosis caused by Enterocytozoon bieneusi and the pattern of intestinal shedding of spores have not been correlated, at least in part because detection of E. bieneusi in stools is more difficult than detection of other protozoa because o
- Multicenter evaluation of new double-antigen sandwich enzyme immunoassay for measurement of anti-human immunodeficiency virus type 1 and type 2 antibodies.
- J Clin Microbiol. 1996 Mar;34(3):634-7. Unique Identifier : AIDSLINE MED/97060107
- Burgisser P; Simon F; Wernli M; Wust T; Beya MF; Frei PC; Division d'Immunologie et Allergie, Centre Hospitalier Universitaire; Vaudois, Lausanne, Switzerland.
- A new enzyme immunoassay (EIA), the Cobas Core Anti-HIV-1/HIV-2 EIA DAGS (also referred to as Roche DAGS), for the detection of antibodies to human immunodeficiency virus type 1 (HIV-1) and HIV-2 was evaluated in four centers. The assay is based on the double-antigen sandwich (DAGS) format, which enables the detection
- Mycobacterium malmoense bacteremia in two AIDS patients.
- J Clin Microbiol. 1996 Mar;34(3):731-3. Unique Identifier : AIDSLINE MED/97060127
- Fakih M; Chapalamadugu S; Ricart A; Corriere N; Amsterdam D; Infectious Diseases Division, Department of Medicine, School of; Medicine, University at Buffalo, NY, USA.
- We report two cases of Mycobacterium malmoense bacteremia in two patients with AIDS. These are the first reported cases of disseminated M. malmoense in human immunodeficiency virus patients occurring in the United States . This slow-growing organism can cause invasive disease mimicking
- Priming of human CD4+ antigen-specific T cells to undergo apoptosis by HIV-infected monocytes. A two-step mechanism involving the gp120 molecule.
- J Clin Invest. 1997 Jan 15;99(2):257-66. Unique Identifier : AIDSLINE MED/97158634
- Cottrez F; Manca F; Dalgleish AG; Arenzana-Seisdedos F; Capron A; Groux H; Unite mixte Institut National de la Sante et de la Recherche Medicale; U167-CNRS 624, Institut Pasteur, Lille, France.
- The study of the pathology of HIV-1 infection in chimpanzees supports the idea of the crucial role of HIV-infected monocytes in the pathogenesis of AIDS, although viral mechanisms that lead to T cell dysfunction and deletion during HIV infection are still unclear. We show here that HIV-1-infected antigen-presenting mo
- Infection control practices in the home: a survey of households of HIV-infected persons with hemophilia [see comments]
- Infect Control Hosp Epidemiol. 1996 Nov;17(11):721-5. Unique Identifier : AIDSLINE MED/97088300
- Lobato MN; Oxtoby MJ; Augustyniak L; Caldwell MB; Wiley SD; Simonds RJ; Division of HIV/AIDS, National Centers for Infectious Diseases,; Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
- OBJECTIVE: To assess infection control practices and risk for human immunodeficiency virus (HIV) transmission in households where home infusion for hemophilia is used. DESIGN: Cross-sectional prospective survey from 1992 through 1994. SETTING: Hemophilia treatment centers. PARTICIPANTS: Human immunodeficiency virus (H
- Attitudes, practices, and infection risks of hemophilia treatment center nurses who teach infection control for the home [see comments]
- Infect Control Hosp Epidemiol. 1996 Nov;17(11):726-31. Unique Identifier : AIDSLINE MED/97088301
- Lobato MN; Hannan J; Simonds RJ; Riske B; Evatt BL; Division of HIV/AIDS, Centers for Disease Control and Prevention,; Atlanta, GA 30333, USA.
- OBJECTIVE: To examine the practices toward infection control training and to assess the attitudes about, and risks for, exposures to blood among hemophilia treatment center (HTC) nurses who teach home infusion therapy (HIT). DESIGN AND POPULATION: Written and telephone interview surveys of the 153 nurses who teach HIT
- Detection of HIV infection in pulmonary tuberculosis patients.
- J Indian Med Assoc. 1996 Sep;94(9):331-3. Unique Identifier : AIDSLINE MED/97171908
- Samuel NM; Alamelu C; Jagannath K; Rajan B; Department of Experimental Medicine/SMT, Tamilnadu Dr MGR Medical; University, Madras.
- Well documented 112 pulmonary tuberculosis patients were studied for the prevalence of human immunodeficiency virus (HIV) seropositivity by using two antibody screening tests along with western blot test. Nineteen of the pulmonary tuberculosis patients were HIV seropositive, 12 were acid-fast bacillus smear positive;
- Transcriptional activation of the human immunodeficiency virus long terminal repeat sequences by retinoic acid in human epithelial and fibroblast tumor cell lines.
- Int J Biol Markers. 1996 Jul-Sep;11(3):153-8. Unique Identifier : AIDSLINE MED/97072962
- Zoumpourlis V; Ergazaki M; Spandidos DA; Institute of Biological Research and Biotechnology, National Hellenic; Research Foundation, Athens, Greece.
- We employed a recombinant plasmid, pBHIV1, carrying the long terminal repeat (LTR) sequences of HIV-1 linked to the reporter chloramphenicol acetyl transferase (CAT) gene and to the aminoglycoside phosphotransferase (aph) gene as a selectable marker. We introduced pBHIV1 into human epithelial and fibroblast tumor cell
- [AIDS and tuberculosis]
- Nippon Naika Gakkai Zasshi. 1996 Jan 10;85(1):129-34. Unique Identifier : AIDSLINE MED/97025098
- Tanaka K
- Marked inhibition of the intracellular multiplication of Legionella pneumophila in monocytes isolated from carriers of human T lymphotrophic virus type I.
- J Leukoc Biol. 1997 Feb;61(2):133-40. Unique Identifier : AIDSLINE MED/97174183
- Funai N; Shimamoto Y; Watanabe M; Yoshida SI; Kohashi O; Department of Internal Medicine, Saga Medical School, Japan.
- Intracellular growth patterns of Legionella pneumophila were examined in monocytes obtained from carriers of human T-lymphotropic virus type I (HTLV-1) and controls who were HTLV-1 seronegative. All subjects were seronegative for antibodies against L. pneumophila. Bacterial growth was determined 0, 1, 2, and/or 3 days
- CD40-CD40L interactions provide "third-party" costimulation for T cell response against B7-1-transfected human breast tumor cells.
- J Leukoc Biol. 1997 Feb;61(2):201-8. Unique Identifier : AIDSLINE MED/97174192
- Pericle F; Epling-Burnette PK; Podack ER; Wei S; Djeu JY; Experimental Immunology Branch, National Cancer Institute, Bethesda,; Maryland 20892, USA.
- In this study we provide evidence that a human breast carcinoma cell line, MDA-MB-231 (MDA), can be made immunogenic following B7 transfection and that full T cell activation is obtained through cooperation of T-B lymphocytes via CD40-CD40L interactions. Tumor cells transfected with either B7 gene (MDAB7), neomycin-re
- Proteolytic activity in vivo and encapsidation of recombinant human immunodeficiency virus type 1 proteinase expressed in baculovirus-infected cells.
- J Gen Virol. 1997 Jan;78 ( Pt 1):131-42. Unique Identifier : AIDSLINE MED/97163476
- Royer M; Bardy M; Gay B; Tournier J; Boulanger P; Laboratoire de Virologie et Pathogenese Moleculaires, CNRS; URA-1487,Institut de Biologie, Faculte de Medecine, Montpellier,; France.
- The activity in vivo of HIV-1 proteinase (PR) was analysed in the baculovirus expression system, using eight different constructs of the prt gene under the control of polyhedrin (PH) promoters of various strengths. None of the active PRs was expressed in substantial quantities, and only PH-fused and/or non-functional
- Infection of choroid plexus cells by human T cell leukaemia virus type I.
- J Gen Virol. 1997 Jan;78 ( Pt 1):143-6. Unique Identifier : AIDSLINE MED/97163477
- Coscoy L; Gonzalez-Dunia D; Brahic M; Ozden S; Unite de Virus Lents, URA 1157 CNRS, Institut Pasteur, Paris, France.
- Very little is known about the factors that determine the outcome of infection by human T cell leukaemia virus type I (HTLV-I) and the neurotropism of this virus is still a controversial point. In transgenic mice, the HTLV-I LTR is active mainly in the central nervous system (CNS), in parenchyma as well as in ependyma
- Long-term persistence of protective immunity in cynomolgus monkeys immunized with a recombinant vaccinia virus expressing the human T cell leukaemia virus type I envelope gene.
- J Gen Virol. 1997 Jan;78 ( Pt 1):147-52. Unique Identifier : AIDSLINE MED/97163478
- Ibuki K; Funahashi SI; Yamamoto H; Nakamura M; Igarashi T; Miura T; Ido E; Hayami M; Shida H; Institute for Virus Research, Kyoto University, Japan.
- To develop effective vaccines against infection with human T cell leukaemia virus type I (HTLV-I), we constructed a recombinant vaccinia virus (WR-SFB5env) synthesizing the HTLV-I envelope Env) gp46 protein under the control of a strong promoter, termed the ATI hybrid promoter. WR-SFB5env expressed a large quantity of
- Bovine leukaemia virus-induced lymphocytosis in sheep is associated with reduction of spontaneous B cell apoptosis.
- J Gen Virol. 1997 Jan;78 ( Pt 1):153-62. Unique Identifier : AIDSLINE MED/97163479
- Schwartz-Cornil I; Chevallier N; Belloc C; Le Rhun D; Laine V; Berthelemy M; Mateo A; Levy D; URA INRA d'Immuno Pathologie Cellulaire et Moleculaire,; Maisons-Alfort, France. schwartz@jouy.inra.fr
- Experimental inoculation of sheep with bovine leukaemia virus BLV), a retrovirus homologous to the human T-lymphotropic virus type 1 (HTLV-1), induces a chronic expansion of the B lymphocyte population (persistent lymphocytosis) and the development of a B cell leukaemia/lymphosarcoma syndrome. To gain insight into the
- An anti-fusion regulatory protein-1 monoclonal antibody suppresses human parainfluenza virus type 2-induced cell fusion.
- J Gen Virol. 1997 Jan;78 ( Pt 1):83-9. Unique Identifier : AIDSLINE MED/97163469
- Okamoto K; Tsurudome M; Ohgimoto S; Kawano M; Nishio M; Komada H; Ito M; Sakakura Y; Ito Y; Department of Microbiology, Mie University School of Medicine,; Edobashi, Tsu-Shi, Japan.
- Fusion regulatory protein-1 (FRP-1) regulates virus-mediated cell fusion and induces poly-karyocyte formation of monocytes without any fusogen. We have recently reported that FRP-1 and the 4F2/CD98 heavy chain are identical molecules. Cell fusion in Newcastle disease virus (NDV)-infected HeLa cells was enhanced when c
- Regulated expression vectors demonstrate cell-type-specific sensitivity to human immunodeficiency virus type 1 Nef-induced cytostasis.
- J Gen Virol. 1997 Feb;78 ( Pt 2):381-92. Unique Identifier : AIDSLINE MED/97170757
- Cooke SJ; Coates K; Barton CH; Biggs TE; Barrett SJ; Cochrane A; Oliver K; McKeating JA; Harris MP; Mann DA; University Clinical Biochemistry, University of Southampton School of; Medicine, Southampton General Hospital, UK.
- The nef gene product of both human and simian immunodeficiency viruses is critically important for virus replication and disease progression in vivo. However, the precise biological function of Nef remains poorly characterized in vitro, with previous reports suggesting that Nef might be either cytotoxic or cytostatic.
- Diversity of the vif gene of human immunodeficiency virus type 1 in Uganda.
- J Gen Virol. 1997 Feb;78 ( Pt 2):393-400. Unique Identifier : AIDSLINE MED/97170758
- Wieland U; Seelhoff A; Hofmann A; Kuhn JE; Eggers HJ; Mugyenyi P; Schwander S; Institut fur Virologie, Universitat zu Koln, Germany.; ulrike.wieland@uni-koeln.de
- Little sequence information is available for human immunodeficiency virus type 1 (HIV-1) vif genes of African origin. Here we describe 37 new complete vif genes of 18 AIDS patients from Uganda and show that vif has a high in vivo genetic variability. vif proviral DNA sequences of p
- Lack of predictive value for progression of dissociated circulating P24 antigen in human immunodeficiency virus type 1-infected black patients.
- J Med Virol. 1996 Oct;50(2):181-7. Unique Identifier : AIDSLINE MED/97073137
- Prazuck T; Troisvallets D; Vallantin X; Patey O; Matta M; Fisch A; Lesguiller C; Si Mohammed A; Thomas M; Lafaix C; Belec L; Department des Maladies Infectieuses, Centre Hospitalier; Universitaire, Villeneuve St Georges, France.
- In human immunodeficiency virus type 1 (HIV)-1-infected Black people, the circulating p24 antigen is hidden frequently in immune complexes, because of high titers of serum anti-p24 antibodies. In order to evaluate the prognostic values for progression of free and dissociated serum p24 antigen in Black people, sera fro
- Seroepidemiology of new AIDS-associated adenoviruses among the San Francisco Men's Health Study.
- J Med Virol. 1996 Nov;50(3):230-6. Unique Identifier : AIDSLINE MED/97082044
- Crawford-Miksza L; Schnurr DP; Viral and Rickettsial Disease Laboratory, California Department of; Health Services, Berkeley 94704, USA.
- A seroprevalence survey to recently proposed adenovirus (AV) serotypes AV 48 and AV 49, isolated primarily from AIDS patients, was conducted among the San Francisco Men s Health Study cohort. This cohort of homosexual, heterosexual, or bisexual HIV-seronegative and seropositive men from selected San Francisco census t
- Significance of placental damage in vertical transmission of human immunodeficiency virus.
- J Med Virol. 1996 Nov;50(3):237-43. Unique Identifier : AIDSLINE MED/97082045
- Burton GJ; O'Shea S; Rostron T; Mullen JE; Aiyer S; Skepper JN; Smith R; Banatvala JE; Department of Anatomy, University of Cambridge, UK.
- The significance of physical breaches of the trophoblastic layer of the placenta in transmission of HIV from mother to infant was evaluated in 17 HIV-infected pregnant women. Samples of peripheral blood were obtained from the women during pregnancy and at delivery, at which time a small piece of placental tissue was o
- Molecular analysis of mixed infection with hepatitis C virus and human immunodeficiency virus in a patient infected simultaneously.
- J Med Virol. 1996 Nov;50(3):276-82. Unique Identifier : AIDSLINE MED/97082051
- Mazza C; Puoti M; Ravaggi A; Castelnuovo F; Albertini A; Cariani E; III Laboratory of Clinical Chemistry, Hospital of Brescia, Italy.
- A case of simultaneous infection with HIV and HCV characterized by a rapidly progressive clinical course was studied retrospectively over 3.5 years. Molecular analysis indicated interference between HIV and HCV and between HCV subtypes 1a and 1b. An ineffective immune response was suggested by the persistence and sequ
- Comparative evaluation of three assays for the quantitation of human immunodeficiency virus type 1 RNA in plasma.
- J Med Virol. 1996 Dec;50(4):293-302. Unique Identifier : AIDSLINE MED/97107985
- Coste J; Montes B; Reynes J; Peeters M; Segarra C; Vendrell JP; Delaporte E; Segondy M; Etablissement de Transfusion Sanguine Languedoc-Roussillon, Centre; Hospitalier Universitaire, Montpellier, France.
- Reverse transcriptase-coupled polymerase chain reaction (Amplicor HIV-1 Monitor), the branched DNA (bDNA) method (Quantiplex HIV-1 RNA) and the nucleic acid sequence-based assay (NASBA HIV-1 RNA QT) were comparatively evaluated for the quantitation of human immunodeficiency virus type 1 (HIV-1) RNA in plasma. Among 60
- Accepting our responsibility for treating AIDS patients [letter]
- J Oral Maxillofac Surg. 1997 Feb;55(2):204. Unique Identifier : AIDSLINE MED/97176826
- Smail DB
- Meningitis caused by Rhodotorula rubra in an HIV-infected patient.
- J Med Vet Mycol. 1996 Sep-Oct;34(5):357-9. Unique Identifier : AIDSLINE MED/97068983
- Gyaurgieva OH; Bogomolova TS; Gorshkova GI; Centre for Deep Mycoses of Medical Academy for Postgraduate Training,; St Petersburg, Russia.
- Meningitis caused by Rhodotorula spp. in HIV-infected patients has not been reported previously. We present a brief review of the literature regarding medically important species of Rhodotorula and a case of meningitis caused by Rhodotorula rubra in an HIV-infected patient. The diagnosis was confirmed by the isolation
- Women and HIV infection: investigation of its psychosocial consequences.
- J Psychosom Res. 1996 Jul;41(1):39-47. Unique Identifier : AIDSLINE MED/97042617
- Catalan J; Beevor A; Cassidy L; Burgess AP; Meadows J; Pergami A; Gazzard B; Barton S; Charing Cross and Westminster Medical School, Psychological Medicine; Unit, Chelsea and Westminster Hospital, London, UK.
- HIV infection is associated with substantial psychological and social morbidity, although there is a dearth of studies of women with the infection. In recent years, developed countries have reported an increase in the prevalence of HIV infection in women, a fact that makes it all the more important to address the stud
- Concurrent Sweet's syndrome and Lofgren's syndrome.
- J Rheumatol. 1996 Nov;23(11):1995-8. Unique Identifier : AIDSLINE MED/97082139
- Cuende Quintana E; Gomez Rz de Mendarozqueta M; Gorospe Arrazuria MA; Saracibar Oyon N; Atares Pueyo B; Pena MV; Vesga Carasa JC; Rheumatology Unit, Hospital Txagorritxu, Pais Vasco, Spain.
- Concurrent Sweet s syndrome and acute sarcoidosis (Lofgren s syndrome) has been reported in 4 cases. We describe a 40-year-old woman with biopsy confirmed lesions of Sweet s syndrome and erythema nodosum together with arthritis and hilar and mediastinal adenopathy. We review the association of Sweet s syndrome and mal
- Cyclic urea amides: HIV-1 protease inhibitors with low nanomolar potency against both wild type and protease inhibitor resistant mutants of HIV.
- J Med Chem. 1997 Jan 17;40(2):181-91. Unique Identifier : AIDSLINE MED/97157135
- Jadhav PK; Ala P; Woerner FJ; Chang CH; Garber SS; Anton ED; Bacheler LT; DuPont Merck Research Laboratories, DuPont Merck Pharmaceutical; Company, Wilmington, Delaware 19880, USA.; jadhavpk@a1.lldmpc.umc.dupont.com
- Cyclic urea amides, a novel series of HIV-1 protease (HIV PR) inhibitors, have increased activity against drug-resistant mutants of the HIV PR. The design strategy for these inhibitors is based on the hypotheses that (i) the hydrogen-bonding interactions between the inhibitor and the protease backbone will remain cons
- Coumarin-based inhibitors of HIV integrase.
- J Med Chem. 1997 Jan 17;40(2):242-9. Unique Identifier : AIDSLINE MED/97157142
- Zhao H; Neamati N; Hong H; Mazumder A; Wang S; Sunder S; Milne GW; Pommier Y; Burke TR Jr; Laboratory of Medicinal Chemistry, National Cancer Institute, National; Institutes of Health, Bethesda, Maryland 20892, USA.
- The structures of a large number of HIV-1 integrase inhibitors have in common two aryl units separated by a central linker. Frequently at least one of these aryl moieties must contain 1,2-dihydroxy substituents in order to exhibit high inhibitory potency. The ability of o-dihydroxy-containing species to undergo in sit
- Sero-prevalence of HIV: six years' experience at Shaikh Zayed Hospital, Lahore.
- JPMA J Pak Med Assoc. 1996 Nov;46(11):255-8. Unique Identifier : AIDSLINE MED/97153888
- Iqbal J; Rehan N; Department of Microbiology, Pakistan Medical Research Council, Lahore.
- Sero-prevalence of HIV was tested among 16,170 individuals. They included 215 patients with sexually transmitted diseases (STD), 77 I/V drug users, 21 commercial sex workers, 987 patients on haemodialysis, 119 subjects referred for HIV testing, 12,482 voluntary blood donors, 360 ante-natal attenders, 73 tuberculosis p
- [Identification of T cell epitopes by reverse immunogenetics]
- Nippon Rinsho. 1996 Dec;54(12):3379-88. Unique Identifier : AIDSLINE MED/97130335
- Takiguchi M; Department of Tumor Biology, University of Tokyo.
- Novel Strategy to identify CTL epitopes called reverse immunogenetics was introduced. CTL epitopes were identified as follows; (i) Identification of the motif of HLA class I binding peptides (ii) Selection of sequences matched to the motif of HLA class I binding peptides from HIV proteins and synthesis of peptides (
- [Detection of HIV-1 in plasma samples using microplate hybridization after RT-PCR]
- Rinsho Byori. 1996 Dec;44(12):1169-74. Unique Identifier : AIDSLINE MED/97145277
- Suzuki H; Fukushima K; Matsuo M; Hashimoto N; Yoshihara N; AIDS Research Center, National Institute of Health, Tokyo.
- We have developed a microplate hybridization(MH) technique, which utilizes the non-isotopic method of enzyme-linked assay for detection of HIV in the amplified product after PCR. HIV RNA extracted from plasma was amplified by RT-Nested-PCR using biotinylated-inner primers of gag, pol and env regions, respectively. The
- [Six patients with pneumonitis related to blended Chinese traditional medicines]
- Nippon Kyobu Shikkan Gakkai Zasshi. 1996 Dec;34(12):1331-6. Unique Identifier : AIDSLINE MED/97174618
- Yamawaki I; Katsura H; Taira M; Kadoriku C; Hashimoto I; Chiyotani A; Kondo M; Tamaoki J; Nagai A; Konno K; Department of Medicine, Seirei Hamamatsu Hospital, Shizuoka, Japan.
- We encountered six patients with pneumonitis related to blended chinese traditional medicine (Kampo). The duration of treatment with kampo ranged from 14 to 110 days (mean: 38 days). The most common complaints were dyspnea, fever, and dry coughing. Fine crackles were heard at the bases of both lungs. Abnormal laborato
- [Sarcoidosis in an 82-year-old woman who presented with ocular symptoms]
- Nippon Kyobu Shikkan Gakkai Zasshi. 1996 Dec;34(12):1375-9. Unique Identifier : AIDSLINE MED/97174626
- Kawano H; Hirata M; Murakami S; Maki K; Yoneda S; Kajita Y; Fujita Y; Department of Internal Medicine, Nantan General Hospital, Kyoto,; Japan.
- An 82-year-old woman with blurred vision consulted an ophthalmologist. She was admitted to the hospital (internal medicine) for further examination because of uveitis and cataracts. A chest X-ray film and a CT scan showed interstitial infiltration in the right middle lung field, and a Ga-scintigram showed abnormal acc
- [Pneumocystis carinii pneumonia associated with high levels of serum KL-6]
- Nippon Kyobu Shikkan Gakkai Zasshi. 1996 Dec;34(12):1420-6. Unique Identifier : AIDSLINE MED/97174635
- Kawakami R; Kikuchi K; Kobayashi J; Shibuya Y; Hagiwara S; Saku N; Hironaka M; Fujii T; Chiba Y; Department of Pulmonary Medicine, Jichi Medical School, Tochigi,; Japan.
- In May 1995, a 52-year-old man complaining of fever and dyspnea was admitted to a hospital. Based on clinical and radiographic findings, hypersensitivity pneumonitis was suspected. Steroid pulse therapy was unsuccessful, and he was then transferred to our hospital. A chest X-ray film showed bilateral ground-glass shad
- [To care humanely and professionally. AIDS: accompaniment and support]
- Krankenpfl Soins Infirm. 1996 May;89(5):88-90. Unique Identifier : AIDSLINE MED/96403478
- Bagnaschi P
- Neural network prediction of the HIV-1 protease cleavage sites.
- J Theor Biol. 1995 Dec 21;177(4):369-79. Unique Identifier : AIDSLINE MED/97025251
- Thompson TB; Chou KC; Zheng C; Department of Chemistry, Northern Illinois University, DeKalb 60115,; USA.
- A back propagation neural network method has been developed to study the pattern of polypeptides that can be cleaved by the HIV-1 protease. This method can incorporate many characteristics of the peptides, such as hydrophobicity, beta-sheet and alpha-helix propensities. Mutations can also be applied to probe the most
- Human herpes virus 8 (Kaposi's sarcoma herpes virus) and malignant lymphoproliferations in France: a molecular study of 250 cases including two AIDS-associated body cavity based lymphomas.
- Leukemia. 1997 Feb;11(2):266-72. Unique Identifier : AIDSLINE MED/97162104
- Gessain A; Briere J; Angelin-Duclos C; Valensi F; Beral HM; Davi F; Nicola MA; Sudaka A; Fouchard N; Gabarre J; Troussard X; Dulmet E; Audouin J; Diebold J; de The G; Unite d'Epidemiologie des Virus Oncogenes, Institut Pasteur, Paris,; France.
- The new human herpes virus 8 (HHV8) was recently detected in cases of body cavity based lymphoma (BCBL), a rare B cell lymphoma, mostly AIDS-associated. We investigated for HHV8 DNA sequences a series of 250 B or T cell lymphoproliferative malignancies, as seen in France , including
- [Cerebral proton spectroscopy of people infected with the human immunodeficiency virus]
- Med Clin (Barc). 1996 Sep 28;107(10):361-5. Unique Identifier : AIDSLINE MED/97081244
- Alonso J; Rovira A; Capellades J; Ocana I; Rio J; Wicklow K; Sauter R; Gili J; Unitat de Ressonancia Magnetica Vall d'Hebron, Institut de Diagnostic; per la lmatge, Barcelona.
- BACKGROUND: This article presents a combined magnetic resonance imaging and proton spectroscopy protocol (MRI/1H-MRS) applied to study the brain of human immunodeficiency virus (HIV) infected patients. The spectroscopic results were compared with clinical and radiological parameters. PATIENTS AND METHODS: The proton s
- [Pseudomonas aeruginosa infection in patients infected with HIV admitted at a hospital unit for prisoners (letter)]
- Med Clin (Barc). 1996 Sep 28;107(10):397-8. Unique Identifier : AIDSLINE MED/97081253
- Tsi L; Aranda M; Simo M; Bella F
- [Quiescent multiple myeloma and HIV infection: coincidence or association? (letter)]
- Med Clin (Barc). 1996 Sep 28;107(10):398-9. Unique Identifier : AIDSLINE MED/97081254
- Trapiella Martinez L; Suarez Moro R; Caminal Montero L; Gonzalez Marroquin A
- [The main causes of death in Spain, 1992; comment]
- Med Clin (Barc). 1996 Oct 12;107(12):441-5. Unique Identifier : AIDSLINE MED/97097136
- Alonso I; Regidor E; Rodriguez C; Gutierrez-Fisac JL; Subdireccion General de Epidermiologia, Ministerio de Sanidad y; Consumo, Madrid.
- BACKGROUND: To study the mortality from the leading causes of death in Spain in 1992 and trends since 1980. POPULATION AND METHOD: The number of deaths was obtained from mortality statistics. We included the 12 causes with the highest mortality rates in 1992 and calculated for each
- [Analysis of the diagnostic delay in tuberculosis]
- Med Clin (Barc). 1996 Oct 12;107(12):453-7. Unique Identifier : AIDSLINE MED/97097138
- Franco J; Blanquer R; Flores J; Fernandez E; Plaza P; Nogueira JM; Servicio de Neumologia, Hospital Dr. Peset, Valencia.
- OBJECTIVE: To identify the situations that influence in the delayed diagnosis of tuberculosis. PATIENTS AND METHOD: We studied 109 patients (87 non HIV-infected and 22 HIV-infected) who were diagnosed of tuberculosis in one year consecutively, using a questionnaire to obtain time intervals in which the whole diagnosti
- [Clinical significance of the genetic variability of the human immunodeficiency virus (editorial)]
- Med Clin (Barc). 1996 Oct 12;107(12):460-3. Unique Identifier : AIDSLINE MED/97097140
- Soriano V; Domingo E
- Arthritis syndromes associated with human T cell lymphotropic virus type I infection.
- Med Clin North Am. 1997 Jan;81(1):261-76. Unique Identifier : AIDSLINE MED/97165002
- McCallum RM; Patel DD; Moore JO; Haynes BF; Department of Medicine, Duke University Medical Center, Durham, North; Carolina, USA.
- Arthritis syndromes occur associated with HTLV-I infection both in the presence and in the absence of clinical ATL, and polyarthritis may be the presenting manifestation of HTLV-I-associated ATL. In both clinical settings, HTLV-I-infected T cells home to affected joints, and tax-transgenic mouse studies have suggested
- Susceptibility to HIV infection and progression of AIDS in relation to variant alleles of mannose-binding lectin.
- Lancet. 1997 Jan 25;349(9047):236-40. Unique Identifier : AIDSLINE MED/97167221
- Garred P; Madsen HO; Balslev U; Hofmann B; Pedersen C; Gerstoft J; Svejgaard A; Department of Clinical Immunology, Rigshospitalet, Copenhagen,; Denmark.
- BACKGROUND: Low serum concentrations of mannose-binding lectin MBL) are associated with increased susceptibility to recurrent infection. Three variant alleles in the MBL gene (B, C, and D), cause low serum concentrations of the protein. We investigated whether variant alleles of MBL affect susceptibility to infection
- Circulating spindle cells: correlation with human herpesvirus-8 HHV-8) infection and Kaposi's sarcoma [letter]
- Lancet. 1997 Jan 25;349(9047):255. Unique Identifier : AIDSLINE MED/97167232
- Sirianni MC; Uccini S; Angeloni A; Faggioni A; Cottoni F; Ensoli B
- US expert panel reaffirms benefit of perinatal zidovudine [news]
- Lancet. 1997 Jan 25;349(9047):258. Unique Identifier : AIDSLINE MED/97167235
- Rowe PM
- Oral HIV test found to be highly accurate [news]
- Lancet. 1997 Jan 25;349(9047):259. Unique Identifier : AIDSLINE MED/97167236
- The katE gene, which encodes the catalase HPII of Mycobacterium avium.
- Mol Microbiol. 1996 Jan;19(1):113-23. Unique Identifier : AIDSLINE MED/96419168
- Milano A; De Rossi E; Gusberti L; Heym B; Marone P; Riccardi G; Dipartimento di Genetica e Microbiologia, Universita degli Studi di; Pavia, Italy.
- Disseminated Mycobacterium avium-Mycobacterium intracellulare disease is a prevalent opportunistic infection in patients with acquired immune deficiency syndrome (AIDS). These pathogens are generally resistant to isoniazid (INH), a powerful antituberculosis drug. It is now generally accepted that the INH susceptibilit
- Characterization of the fibronectin-attachment protein of Mycobacterium avium reveals a fibronectin-binding motif conserved among mycobacteria.
- Mol Microbiol. 1996 Jul;21(2):321-9. Unique Identifier : AIDSLINE MED/97011577
- Schorey JS; Holsti MA; Ratliff TL; Allen PM; Brown EJ; Department of Internal Medicine, Washington University School of; Medicine, St. Louis, Missouri 63110, USA.
- Mycobacterium avium is an intracellular pathogen and a major opportunistic infectious agent observed in patients with acquired immune deficiency syndrome (AIDS). Evidence suggests that the initial portal of infection by M. avium is often the gastrointestinal tract. However, the mechanism by which the M. avium crosses
- Does coinfection of Bartonella henselae and FIV induce clinical disorders in cats?
- Microbiol Immunol. 1996;40(9):617-20. Unique Identifier : AIDSLINE MED/97065055
- Ueno H; Hohdatsu T; Muramatsu Y; Koyama H; Morita C; Department of Veterinary Public Health, School of Veterinary Medicine,; Rakunogakuen University, Hokkaido, Japan.
- It was found that Bartonella henselae (B. henselae) may induce clinical disorders in cats in natural conditions from a comparison of the serological status for B. henselae with the serostatus for feline immunodeficiency virus (FIV) and several clinical characteristics in 170 domestic cats. Seropositivity for B. hensel
- No proof of HTLV-I/II in intravenous drug abusers with a high rate of HIV-1 infection in central Thailand.
- Microbiol Immunol. 1996;40(9):639-44. Unique Identifier : AIDSLINE MED/97065058
- Saguanwongse S; Muangpom A; Ruchusatsawat N; Wongcheree S; Warachit P; Miyamura K; Yamazaki S; Honda M; Virus Research Institute, Department of Medical Sciences, Thailand.
- Serum specimens of 1,074 intravenous drug abusers (IVDA) were examined for infection with HIV-1, HTLV-I and HTLV-II in central Thailand . Three hundred and sixty-two of the specimens were seropositive for HIV-1 (33.7%). The HIV-1 seropositive IVDAs exhibited increased seropositivi
- Development of functional rat-derived T cells in SCID mice engrafted with the fetal thymus of LEC rats which are defective in CD4+ T cells.
- Microbiol Immunol. 1996;40(9):659-64. Unique Identifier : AIDSLINE MED/97065061
- Chai JG; Sakai T; Hisaeda H; Nagasawa H; Yasutomo K; Furukawa A; Ishikawa H; Maekawa Y; Uehara H; Izumi K; Matsumoto K; Himeno K; Department of Parasitology and Immunology, University of Tokushima; School of Medicine, Japan.
- We reported that LEC rats are genetically deficient in the development of thymic CD4+8- cells and that this defect is caused by bone marrow (BM)-derived stem cells. To determine which BM-derived cells are responsible for the arrest of T-cell development in LEC rats, fetal thymuses of LEC rats, or LEA rats which bear t
- Informed consent is required for HIV testing [news]
- Minn Med. 1996 Nov;79(11):36. Unique Identifier : AIDSLINE MED/97121067
- Sporozoites of Toxoplasma gondii lack dense-granule protein GRA3 and form a unique parasitophorous vacuole.
- Mol Biochem Parasitol. 1995 Dec;75(1):75-86. Unique Identifier : AIDSLINE MED/96362063
- Speer CA; Tilley M; Temple ME; Blixt JA; Dubey JP; White MW; Department of Veterinary Molecular Biology, Montana State University,; Bozeman 59717, USA.
- The invasion of host cells by sporozoites of Toxoplasma gondii leads to the formation of parasitophorous vacuoles that are distinctly different from those surrounding tachyzoites. In sporozoite-infected cells, the fluid-filled space surrounding the sporozoite is many times larger in volume than the sporozoite, essenti
- Remission of progressive multifocal leukoencephalopathy following splenectomy and antiretroviral therapy in a patient with HIV infection [letter]
- N Engl J Med. 1997 Feb 27;336(9):661-2. Unique Identifier : AIDSLINE MED/97170838
- Power C; Nath A; Aoki FY; Bigio MD
- [Mycobacterium avium infection in HIV-infected patients: epidemiology, diagnosis, prevention and treatment (see comments)]
- Ned Tijdschr Geneeskd. 1997 Jan 11;141(2):80-3. Unique Identifier : AIDSLINE MED/97166704
- Schneider MM; Reiss P; Borleffs JC; Rozenberg-Arska M; Hoepelman IM; Afd. Interne Geneeskunde, Academisch Ziekenhuis, Utrecht.
- The prevalence of infection with Mycobacterium avium complex MAC) has increased since the outbreak of the HIV pandemic. This complex comprises two organisms: M. avium (mostly) and M. intracellulare (rarely). The source of MAC infection is not known. The principal risk factors for disseminated MAC infection in a patien
- [Sensory Jacksonian seizures as initial manifestation of sarcoidosis]
- Nervenarzt. 1996 Oct;67(10):883-5. Unique Identifier : AIDSLINE MED/97126859
- Meincke U; Mull M; Weis J; Topper R; Neurologische Klinik, RWTH Aachen.
- A 46-year old patient is reported presenting with somatosensory focal seizures of either arm as the only manifestation of an otherwise clinically inapparent sarcoidosis. MRI showed signs of a granulomatous leptomeningeal affection. Histological examination of a meningeal biopsy proved the diagnosis of sarcoidosis by d
- AIDS-associated renal tuberculosis.
- Nephron. 1996;74(4):701-4. Unique Identifier : AIDSLINE MED/97114570
- Marques LP; Rioja LS; Oliveira CA; Santos OD; Department of Medicine, University of Rio de Janeiro, Brazil.
- In order to study the prevalence and the clinical features of renal tuberculosis associated with AIDS, we studied the renal tissue of the necropsies made in 46 AIDS patients under light microscopy. We found renal tuberculous granuloma in 11 (23%) patients (in 3 without previous diagnosis of renal or extrarenal tubercu
- Idiopathic dural herniation of the thoracic spinal cord.
- Neuroradiology. 1996 Aug;38(6):503-10. Unique Identifier : AIDSLINE MED/97035050
- Hausmann ON; Moseley IF; Lysholm Radiological Department, National Hospital for Neurology and; Neurosurgery, London, UK.
- Symptomatic anterior or anterolateral dural herniation of the spinal cord is rare, and not uncommonly misdiagnosed, both clinically and radiologically. We present four patients with a radiological diagnosis of herniation of the thoracic spinal cord, and review the current literature. All affected patients have been ad
- The "target sign": is it a specific sign of CNS tuberculoma?
- Neuroradiology. 1996 Aug;38(6):547-50. Unique Identifier : AIDSLINE MED/97035060
- Bargallo J; Berenguer J; Garcia-Barrionuevo J; Ubeda B; Bargallo N; Cardenal C; Mercader JM; Department of Neuroradiology, Hospital Clinic i Provincial, University; of Barcelona, Spain.
- In brain lesions, the target sign has been defined as a central nidus of calcification or central enhancement surrounded by a ring of enhancement. It has been considered a pathognomonic finding of central nervous system (CNS) tuberculoma. The purpose of this report is to demonstrate that the target sign related to cen
- Myelopathy among Brazilians coinfected with human T-cell lymphotropic virus type I and HIV.
- Neurology. 1997 Jan;48(1):13-8. Unique Identifier : AIDSLINE MED/97161229
- Harrison LH; Vaz B; Taveira DM; Quinn TC; Gibbs CJ; de Souza SH; McArthur JC; Schechter M; Department of International Health, Johns Hopkins University School of; Hygiene, Baltimore, MD, USA. LHARRISO+@PITT.EDU
- OBJECTIVE: To determine whether subjects coinfected with HTLV-I and HIV have a higher frequency of myelopathy than subjects singly infected with HIV. DESIGN: A prospective, nested case-control study of HTLV-I and HIV coinfected (cases) and HIV singly infected adults (controls) participating in a prospective HIV cohort
- HIV infection and cognition in intravenous drug users: long-term follow-up.
- Neurology. 1997 Jan;48(1):223-30. Unique Identifier : AIDSLINE MED/97161265
- Selnes OA; Galai N; McArthur JC; Cohn S; Royal W 3rd; Esposito D; Vlahov D; Department of Neurology, Johns Hopkins University School of Medicine,; Baltimore, MD 21287, USA.
- A cohort of 185 HIV-infected injection drug users (IDUs) and seronegative controls was followed with semiannual neuropsychological assessments for up to 4.5 years. Changes in cognitive performance over time were evaluated, and results of seronegative controls were used to adjust for level of education and practice eff
- Protease inhibitors [news]
- Nurse Pract. 1996 Oct;21(10):125-8. Unique Identifier : AIDSLINE MED/97050469
- Klaus BD
- Herpes simplex virus keratitis among patients who are positive or negative for human immunodeficiency virus: an epidemiologic study.
- Ophthalmology. 1997 Jan;104(1):120-4. Unique Identifier : AIDSLINE MED/97174381
- Hodge WG; Margolis TP; Francis I. Proctor Foundation for Research in Ophthalmology, San; Francisco, CA 94122, USA.
- PURPOSE: The authors compare the incidence and clinical course of herpes simplex virus (HSV) keratitis among patients who are positive and negative for human immunodeficiency virus (HIV). METHODS: A retrospective cohort study was designed. Outcomes measured in both groups included incidence of HSV keratitis, lesion ty
- Human herpesvirus 6 (HHV-6) ORF-1 transactivating gene exhibits malignant transforming activity and its protein binds to p53.
- Oncogene. 1997 Jan 23;14(3):359-67. Unique Identifier : AIDSLINE MED/97170818
- Kashanchi F; Araujo J; Doniger J; Muralidhar S; Hoch R; Khleif S; Mendelson E; Thompson J; Azumi N; Brady JN; Luppi M; Torelli G; Rosenthal LJ; Laboratory of Molecular Virology, National Cancer Institute, National; Institutes of Health, Bethesda, Maryland 20892, USA.
- The 357 amino acid open reading frame 1 (ORF-1), also designated DR7, within the SalI-L fragment of human herpesvirus 6 (HHV-6) exhibited transactivation of the human immunodeficiency virus type 1 (HIV-1) long terminal repeat (LTR) promoter and increased HIV-1 replication (Kashanchi et al., Virology, 201, 95-106, 1994
- Detection of human viruses in periodontal pockets using polymerase chain reaction.
- Oral Microbiol Immunol. 1996 Oct;11(5):289-93. Unique Identifier : AIDSLINE MED/97180035
- Parra B; Slots J; Department of Periodontology, School of Dentistry, University of; Southern California, Los Angeles 90089-0641, USA.
- Even though viruses have been implicated in the etiology of several medical and dental disorders, little or no data are available on the possible involvement of human viruses in the pathogenesis of human periodontal disease. This study investigated the presence of human cytomegalovirus
- HIV/AIDS and Related Issues Forum.
- N J Nurse. 1996 Dec;26(10):8. Unique Identifier : AIDSLINE MED/97178092
- Vitiello-Taylor MA
- Ophthalmic complications of HIV/AIDS.
- Postgrad Med J. 1996 Dec;72(854):725-30. Unique Identifier : AIDSLINE MED/97167848
- Ah-Fat FG; Batterbury M; St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool,; UK.
- As a result of improved treatment and patient survival, ophthalmic complications are now being seen with increasing frequency in AIDS, occurring in up to 75% of patients during the course of the disease. The eye may be involved by an AIDS-related microvasculopathy, which gives rise to cotton wool spots, and by opportu
- Synthesis of novel thiazolo[4,5-d]pyrimidine derivatives for antimicrobial, anti-HIV and anticancer investigation.
- Pharmazie. 1996 Dec;51(12):927-31. Unique Identifier : AIDSLINE MED/97139013
- Rida SM; Habib NS; Badawey EA; Fahmy HT; Ghozlan HA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy,; University of Alexandria, Egypt.
- Some novel thiazolo[4,5-d]pyrimidines containing 6-arylideneamino 3a-e). 2-dicyanomethylidene (5a), 2-(cyanoethoxy carbonyl) methylidene (5b) or 2-hydrazono (7a, b) moieties were synthesized. The prepared compounds were tested in vitro for their antibacterial, antifungal, anti-HIV and anticancer activities. Most of th
- Psychopharmacology in HIV-positive patients: research perspectives.
- Psychopharmacol Bull. 1996;32(3):293-7. Unique Identifier : AIDSLINE MED/97121104
- Vitiello B; Stover ES; National Institute of Mental Health, Office on AIDS, Rockville, MD; 20857, USA.
- Psychotropic medications play an important role in the treatment of human immunodeficiency virus (HIV)-positive subjects suffering from neuropsychiatric disorders or other acquired immunodeficiency syndrome (AIDS)-related symptomatology. The quality of life of these patients can be significantly improved by the approp
- [Inflammatory diseases of the spinal cord and spinal nerve roots in the MRI]
- Radiologe. 1996 Nov;36(11):897-913. Unique Identifier : AIDSLINE MED/97114658
- Sartoretti-Schefer S; Wichmann W; Valavanis A; Institut fur Neuroradiologie, Universitatsspital Zurich.
- PURPOSE: To evaluate characteristic and reliable MRI patterns of different inflammatory lesions of the spinal cord and the nerve roots in immunologically compromised and immunologically competent patients in order to be able to establish a correct diagnosis based on MRI findings. MATERIAL AND METHODS: The MRI examinat
- [NF-kappa B system]
- Tanpakushitsu Kakusan Koso. 1996 Jun;41(8 Suppl):1198-209. Unique Identifier : AIDSLINE MED/96316692
- Watanabe N; Fujita T; Department of Tumor Cell Biology, Tokyo Metropolitan Institute of; Medical Science, Japan.
- [Interaction of HTLV-1 Tax with cellular factors]
- Tanpakushitsu Kakusan Koso. 1996 Jun;41(8 Suppl):1249-57. Unique Identifier : AIDSLINE MED/96316697
- Suzuki T; Yoshida M; Department of Cellular and Molecular Biology, University of Tokyo,; Japan.
- [Periodontal disease in patients with HIV infection. Radiographic study]
- Radiol Med (Torino). 1996 Nov;92(5):562-8. Unique Identifier : AIDSLINE MED/97157172
- Scutellari PN; Orzincolo C; Guarnelli EM; Dipartimento di Scienze Biomediche e Terapie Avanzate, Universita; degli Studi, Ferrara.
- A painful and rapidly progressive form of periodontitis--involving both soft tissue and bone, with gingival bleeding and loss of teeth--was observed in HIV-patients in the mid-80 s. Today, there are few reports regarding the real incidence of periodontitis in HIV populations: however, it seems not as high as first sup
- [Pneumocystis infection in a non-immunocompromised patient]
- Rev Mal Respir. 1996 Dec;13(6):603-6. Unique Identifier : AIDSLINE MED/97161689
- Yassine N; el Meziane A; Alaoui YA; Bartal M; Service des Maladies Respiratoires, Centre Hospitalier Universitaire; Ibn Rochd, Casablanca, Maroc.
- Pneumocystis is typically described in the immunodepressed. We report a case of pneumocystis occurring in a patient without known depression of the immune system. The patient, aged 50, was hospitalised for a diffused infiltration pneumonia which developed sub-acutely, and presented with increasing dyspnoea of effort,
- Quantification of hepatitis C virus RNA in peripheral blood mononuclear cells: a comparison between patients chronically infected by HCV and patients coinfected by HIV.
- Res Virol. 1996 Nov-Dec;147(6):325-32. Unique Identifier : AIDSLINE MED/97117548
- Cribier B; Rey D; Uhl G; Schmitt C; Libbrecht E; Vetter D; Lang JM; Kirn A; Stoll-Keller F; INSERM U74, Strasbourg, France.
- In patients chronically infected by hepatitis C virus (HCV), peripheral blood mononuclear cells (PBMCs) were shown to be targets for virus replication and in those coinfected with HIV, HCV viraemia was considerably increased. The purpose of this study was to quantify HCV RNA in PBMCs from 25 patients infected by HCV a
- Type D retrovirus markers in healthy Africans from Guinea.
- Res Virol. 1996 Nov-Dec;147(6):341-51. Unique Identifier : AIDSLINE MED/97117550
- Morozov VA; Lagaye S; Lyakh L; ter Meulen J; Laboratory of Molecular Virology and Carcinogenesis, NCI-Frederick; Cancer Research and Development Center, MD 21702, USA.
- Sixteen matching sera and DNA samples from healthy African blood donors living in rural areas of Guinea were analysed for the presence of type D retrovirus markers. Screening for the antibodies against structural proteins of Mason- Pfizer
- HIV protease and the pathogenesis of AIDS.
- Res Virol. 1996 Nov-Dec;147(6):375-9. Unique Identifier : AIDSLINE MED/97117553
- Goldberg B; Stricker RB; DNCB Study Group, California Pacific Medical Center, San Francisco,; USA.
- Intraoperative diagnostic techniques for stereotactic brain biopsy: cytology versus frozen-section histopathology.
- Stereotact Funct Neurosurg. 1995;65(1-4):187-93. Unique Identifier : AIDSLINE MED/97073643
- Hayden R; Cajulis RS; Frias-Hidvegi D; Brody BA; Yu G; Levy R; Department of Pathology, Northwestern University Medical School,; Chicago, Ill., USA.
- Stereotactic brain biopsy has gained widespread acceptance as a primary diagnostic tool for the evaluation of intracranial lesions. Intraoperative evaluation of such specimens has included the use of both cytological and frozen section histologic techniques. The current study seeks to compare the diagnostic utility of
- Predominance of detrimental humoral immune responses to HIV-1 in AIDS patients with CD4 lymphocyte counts less than 400/mm3.
- Scand J Immunol. 1997 Jan;45(1):103-11. Unique Identifier : AIDSLINE MED/97163700
- McDougall B; Nymark MH; Landucci G; Forthal D; Robinson WE Jr; Department of Pathology, University of California, Irvine 92697-4800,; USA.
- The humoral immune response to human immunodeficiency virus type 1 (HIV-1) was studied in 25 AIDS patients with CD4 lymphocyte counts of less than 400/mm3. Humoral immune responses against tissue culture adapted strains of HIV-1, and two limited-passage patient isolates were investigated. Total anti-HIV antibody level
- HIV antigens and T-cell receptor variable beta chain families.
- Scand J Immunol. 1997 Jan;45(1):81-90. Unique Identifier : AIDSLINE MED/97163697
- Jason J; Inge KL; Orloff SL; Immunology Branch, Centers for Disease Control and Prevention CDC),; Atlanta, GA 30333, USA.
- The authors investigated whether the human immunodeficiency virus HIV) has restrictive effects on the variable region of the beta chain (V beta) of the T-cell antigen receptor (TCR), by in vitro cultivation of non-HIV-infected peripheral blood lymphocytes with one of six HIV antigens or heat-inactivated whole virus (H
- Lymphokine-activated cytotoxicity in peripheral blood mononuclear cells of severely immunocompromised HIV-infected patients.
- Scand J Immunol. 1997 Jan;45(1):91-5. Unique Identifier : AIDSLINE MED/97163698
- Forthal DN; Landucci G; Robinson WE Jr; Department of Medicine, University of California, Irvine College of; Medicine, Orange, USA.
- The authors determined the natural killer (NK) and lymphokine-activated killer (LAK) activities of peripheral blood mononuclear cells (PBMCs) from a severely immunocompromised (CD4 cell counts
- Pattern of HIV viraemia and CD4 levels in relation to pregnancy in HIV-1 infected women.
- Scand J Infect Dis. 1996;28(5):425-33. Unique Identifier : AIDSLINE MED/97111916
- Lindgren S; Martin C; Anzen B; Strand H; Bredberg-R~aden U; Ehrnst A; Department of Immunology, Microbiology, Pathology and Infectious; Diseases, IMPI, Stockholm, Sweden.
- The objective was to study HIV-1 viraemia and CD4 levels during and 6 months after pregnancy. HIV cultures on peripheral blood mononuclear cells (PBMC) and plasma from 225 samples were performed in 90 HIV-1 infected women with 59 continued and 35 terminated pregnancies. P-24 antigen and HIV-DNA were also studied. 34 w
- Hepatitis E virus infection in individuals at high risk of transmission of non-A, non-B hepatitis and sexually transmitted diseases.
- Scand J Infect Dis. 1996;28(5):443-5. Unique Identifier : AIDSLINE MED/97111919
- Psichogiou M; Tzala E; Boletis J; Zakopoulou N; Loutradi A; Maliori M; Kourea-Kremastinou J; Stratigos J; Hatzakis A; Department of Hygiene and Epidemiology, Athens University Medical; School, Greece.
- The aim of the study was to determine the prevalence of hepatitis E virus (HEV) infection among individuals at high risk of transmission of non-A, non-B hepatitis or sexually transmitted diseases (STDs), and to evaluate whether they have an increased risk of exposure to HEV. Serum samples from 125 thalassemia patients
- Glycoprotein B genotype of human cytomegalovirus: distribution in HIV-infected patients.
- Scand J Infect Dis. 1996;28(5):447-9. Unique Identifier : AIDSLINE MED/97111920
- Bongarts A; Von Laer D; Vogelberg C; Ebert K; Van Lunzen J; Garweg J; Vaith P; Hufert FT; Haller O; Meyer-Konig U; Abteilung Virologie, Universitat Freiburg, Germany.
- Glycoprotein B (gB) is involved in cell to cell transmission of human cytomegalovirus (HCMV) and may be a critical factor in tissue tropism and viral pathogenesis. We analyzed the distribution of the four known gB genotypes of HCMV in 99 HIV-positive patients. 29 patients had HCMV
- Rhodococcus equi infection in HIV-positive subjects: a retrospective analysis of 24 cases.
- Scand J Infect Dis. 1996;28(5):463-7. Unique Identifier : AIDSLINE MED/97111924
- Arlotti M; Zoboli G; Moscatelli GL; Magnani G; Maserati R; Borghi V; Andreoni M; Libanore M; Bonazzi L; Piscina A; Ciammarughi R; Division of Infectious Diseases, Rimini Hospital, Italy.
- Rhodococcus equi causes a rare infection in immunocompromised hosts. We describe 24 cases of infection in patients with AIDS-related complex (ARC)/acquired immunodeficiency syndrome AIDS). Pneumonia was always the first manifestation of R. equi infection, but extrapulmonary involvement was also observed. The main sour
- Drug resistance patterns among tuberculosis patients in Rome, 1990-1992.
- Scand J Infect Dis. 1996;28(5):487-91. Unique Identifier : AIDSLINE MED/97111928
- Girardi E; Antonucci G; Tronci M; Bordi E; Ippolito G; Centro di Riferimento AIDS, Servizio di Epidemiologia delle Malattie; Infettive, Ospedale Lazzaro Spallanzani, Rome, Italy.
- Prevalence of, and risk factors for, drug-resistance of Mycobacterium tuberculosis were assessed among 407 hospitalized patients with tuberculosis in Rome, Italy , during the period 1990-1992. Resistance to 1 or more drugs was detected in 106 isolates (26%). Resistance to streptomyci
- [Organization of a bone and tissue bank. Consequences for organization of bone and tissue banks after HIV and hepatitis C infections]
- Unfallchirurg. 1996 Nov;99(11):880-8. Unique Identifier : AIDSLINE MED/97122907
- Schratt HE; Regel G; Lobenhoffer P; Tscherne H; Unfallchirurgische Klinik. Medizinische Hochschule. Hannover.
- The use of non-treated cryopreserved bone allografts has been criticized following the publication of new cases of HIV and hepatitis-C infection caused by such grafts. However, the new cases of HIV infection arose in 1984/1985. when HIV testing was not possible. A critical analysis of the German bone bank procedures
- Pregnancy and HIV testing: implications for Texas nurses.
- Tex Nurs. 1996 Sep;70(8):8-9. Unique Identifier : AIDSLINE MED/97100887
- Aranda-Naranjo B; Catala S
- Safety and efficacy of monoclonal antibody purified factor IX concentrate in previously untreated patients with hemophilia B.
- Thromb Haemost. 1996 Jan;75(1):30-5. Unique Identifier : AIDSLINE MED/96351766
- Shapiro AD; Ragni MV; Lusher JM; Culbert S; Koerper MA; Bergman GE; Hannan MM; Riley Hospital for Children, Indiana University Medical Center,; Indianapolis 46202-5225, USA.
- The safety and efficacy of a monoclonal antibody purified factor IX concentrate were evaluated in two continuing trials of 32 previously untreated patients with mild, moderate, or severe hemophilia B. Patients were evaluated every 2 weeks for 24 weeks and every 3 months thereafter for at least 1 year. No patients beca
- Compounds with anti-HIV activity from plants.
- Trans R Soc Trop Med Hyg. 1996 Nov-Dec;90(6):601-4. Unique Identifier : AIDSLINE MED/97167875
- Houghton PJ; Department of Pharmacy, King's College, London, UK.
- Natural products are described which have shown activity against human immunodeficiency virus in vitro. These compounds have a variety of chemical structures and modes of action. The discovery of these compounds and features of their development are used to illustrate aspects of the wider use of natural products as no
- Leishmania infantum and L. major in Algeria.
- Trans R Soc Trop Med Hyg. 1996 Nov-Dec;90(6):625-9. Unique Identifier : AIDSLINE MED/97167880
- Harrat Z; Pratlong F; Belazzoug S; Dereure J; Deniau M; Rioux JA; Belkaid M; Dedet JP; Institut Pasteur d'Algerie, El Hamma, Algiers.
- Since 1980, the development of leishmaniasis in Algeria has been marked by a considerable increase in the number of cases of both visceral leishmaniasis (1121 cases recorded) and cutaneous leishmaniasis (more than 2000 cases per year). New Leishmania infantum and L. major foci hav
- Resistance to antituberculosis drugs in rural South Africa: rates, patterns, risks, and transmission dynamics.
- Trans R Soc Trop Med Hyg. 1996 Nov-Dec;90(6):692-5. Unique Identifier : AIDSLINE MED/97167904
- Wilkinson D; Pillay M; Davies GR; Sturm AW; Centre for Epidemiological Research in South Africa, South African; Medical Research Council, Hlabisa, South Africa.
- This study describes the rate, pattern, and transmission dynamics of, and risk factors for, isolates of Mycobacterium tuberculosis resistant to antituberculosis drugs in a rural South African health district. Twenty-one of 254 (7.6%; 95% confidence interval [CI] 4.8-11.4) isolates from incident cases were resistant to
- Human immunodeficiency virus-indeterminate western blot and abortive infection [editorial; comment]
- Transfusion. 1997 Jan;37(1):1-2. Unique Identifier : AIDSLINE MED/97176942
- Jackson JB
- Cost-effectiveness of expanded human immunodeficiency virus-testing protocols for donated blood.
- Transfusion. 1997 Jan;37(1):45-51. Unique Identifier : AIDSLINE MED/97176950
- AuBuchon JP; Birkmeyer JD; Busch MP; Department of Pathology, Dartmouth-Ilitchcock Medical Center, Lebanon,; New Hampshire, USA.
- BACKGROUND: This study was designed to estimate the cost-effectiveness of expanding the human immunodeficiency virus HIV)-testing protocol for donated blood beyond screening for HIV antibodies to further reduce the risk of HIV transmission through transfusion. STUDY DESIGN AND METHODS: A Markov decision analysis model
- Comparative performances of enzyme-linked immunosorbent, western blot, and polymerase chain reaction assays for human T-lymphotropic virus type II infection that is endemic among Indians of the Gran Chaco region of South America.
- Transfusion. 1997 Jan;37(1):52-9. Unique Identifier : AIDSLINE MED/97176951
- Poiesz BJ; Dube S; Jones B; Bryz-Gornia V; Dean MT; Spicer T; Hengst J; Sayre K; Esteban E; Ferrer JF; Department of Medicine, State University of New York, Health Science; Center, Syracuse, USA.
- BACKGROUND: Human T-cell lymphoma/leukemia viruses types I and II HTLV-I and HTLV-II) are related exogenous human retroviruses. The former is definitely pathogenic while disease association with the latter is unclear. There are two subtypes of HTLV-II, A and B. Currently, enzyme-linked immunosorbent assays (ELISAs) ba
- Transfusion transmission of human T-lymphotropic virus type I HTLV-I) from an asymptomatic blood donor: conservation of LTR U3, env, and tax nucleotide sequences in a recipient with HTLV-I-associated myelopathy.
- Transfusion. 1997 Jan;37(1):60-4. Unique Identifier : AIDSLINE MED/97176952
- Gasmi M; D'Incan M; Desgranges C; INSERM U271, Unite de Recherche sur les Hepatites, le SIDA et les; Retrovirus Humains, Lyon, France.
- BACKGROUND: Transfusion of human T-lymphotropic virus type I HTLV-I) contaminated blood is sometimes linked with the rapid onset of HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in immunocompromised recipients. STUDY DESIGN AND METHODS: This study addressed the question of whether HTLV-I variants
- Indeterminate human immunodeficiency virus type 1 western blot may indicate an abortive infection in some low-risk blood donors [see comments]
- Transfusion. 1997 Jan;37(1):65-72. Unique Identifier : AIDSLINE MED/97176953
- Georgoulias VA; Malliaraki NE; Theodoropoulou M; Spanakis E; Fountouli P; Tsatsaki D; Kotsaki S; Karvela-Aggelaki A; Malliaraki-Pinetidou E; AIDS National Reference Center of Crete, Greece.
- BACKGROUND: The infectious status of persons with an indeterminate human immunodeficiency virus type 1 (HIV-1) Western blot must be established. STUDY DESIGN AND METHODS: Evaluation of the CD4 and CD8 T-cell subsets and the expression of HIV-1-integrated sequences by Southern blot and polymerase chain reaction were st
- Soluble interleukin 2 receptor and soluble CD8 levels in previously treated human immunodeficiency virus-negative hemophiliacs multiply transfused with a monoclonal antibody-purified factor VIII concentrate.
- Transfusion. 1997 Jan;37(1):86-9. Unique Identifier : AIDSLINE MED/97176956
- Smid WM; Martens A; van der Meer J; Hegge-Paping CS; Halie MR; Division of Haematology, University Hospital, Groningen, The; Netherlands.
- BACKGROUND: Serum levels of the soluble interleukin 2 receptor sIL-2R) and soluble CD8 (sCD8) may be used as markers of T-cell activation. The course of serum levels of sIL-2R and sCD8 in hemophiliacs who were treated first with an intermediate-purity factor VIII concentrate and then with a monoclonal antibody MoAb)-p
- Disseminated blastomycosis and acquired immunodeficiency syndrome: a case report and ultrastructural study.
- Ultrastruct Pathol. 1996 Sep-Oct;20(5):429-35. Unique Identifier : AIDSLINE MED/97037679
- Guccion JG; Rohatgi PK; Saini NB; French A; Tavaloki S; Barr S; Pathology and Laboratory Medicine Service, Department of Veterans; Affairs Medical Center, Washington, DC 20422, USA.
- A 42-year-old, African-American man presented with a 2-month history of weight loss and fever for 2 weeks. Presumptive diagnoses of human immunodeficiency virus infection (HIV) and acquired immunodeficiency syndrome were made on the basis of a CD4 lymphocyte count of 23 lymphocytes/mL. Chest x-ray revealed right parat
- Positive selection of EqCD8+ precursors increases equine lymphokine-activated killing.
- Vet Immunol Immunopathol. 1996 Sep;53(1-2):1-13. Unique Identifier : AIDSLINE MED/97097306
- Lunn DP; Schram BR; Vagnoni KE; Schobert CS; Horohov DW; Ginther OJ; Department of Medical Sciences, School of Veterinary Medicine,; University of Wisconsin, Madison 53706, USA.
- Lymphokine activated killing (LAK) is an example of natural cytotoxicity, and as such is a critical means of defense against diseases such as viral infection and neoplasia. Despite this important role, the specific molecular interactions involved in LAK or other forms of natural cytotoxicity are only partially underst
- Changes in lymphocyte subsets with age in perinatal cats: late gestation through eight weeks.
- Vet Immunol Immunopathol. 1996 Sep;53(1-2):105-13. Unique Identifier : AIDSLINE MED/97097315
- Sellon RK; Levy JK; Jordan HL; Gebhard DH; Tompkins MB; Tompkins WA; Department of Companion Animal and Special Species, College of; Veterinary Medicine, North Carolina State University, Raleigh 27606,; USA.
- The age-related changes in numbers and proportions of peripheral blood lymphocyte subsets (pan-T, CD4, CD8, Ig, and null) were evaluated by two-color flow cytometry in 16 feline fetuses (56-58 days gestational age) and 21 kittens from birth through 8 weeks of age. Populations of pan-T+, CD4+, and CD8+ cells increased
- Plasmas from lymphocyte- and macrophage-tropic SIVmac-infected macaques have antibodies with a broader spectrum of virus neutralization activity in macrophage versus lymphocyte cultures.
- Virology. 1997 Jan 6;227(1):24-33. Unique Identifier : AIDSLINE MED/97167514
- Zhuge W; Jia F; Adany I; Narayan O; Stephens EB; Marion Merrell Dow Laboratory of Viral Pathogenesis, University of; Kansas Medical Center, Kansas City, Kansas, 66160-7240, USA.
- We examined plasma from macaques infected with three different phenotypes of SIVmac for their ability to neutralize the infectivity of homologous and heterologous virus in lymphocyte CEMx174 cells or normal rhesus macaque peripheral blood lymphocytes) or normal rhesus macaque macrophage (Mphi) cultures. Similar to pre
- Natural endogenous reverse transcription of simian immunodeficiency virus.
- Virology. 1997 Jan 6;227(1):260-7. Unique Identifier : AIDSLINE MED/97167543
- Dornadula G; Zhang H; Bagasra O; Pomerantz RJ; Center for Human Virology, Division of Infectious Diseases, Department; of Medicine, Jefferson Medical College, Thomas Jefferson University,; 1020 Locust Street, Suite 329, Philadelphia, Pennsylvania, 19107, USA.
- It has been demonstrated that human immunodeficiency virus type 1 HIV-1) virions are biochemically active particles, within which reverse transcription can take place even in physiological microenvironments. This process has been termed natural endogenous reverse transcription (NERT). In this report, we demonstrate
- Identification of HIV-1 determinants for replication in vivo.
- Virology. 1997 Jan 6;227(1):45-52. Unique Identifier : AIDSLINE MED/97167516
- Su L; Kaneshima H; Bonyhadi ML; Lee R; Auten J; Wolf A; Du B; Rabin L; Hahn BH; Terwilliger E; Mccune JM; HIV Group, SyStemix, Inc., 1501 California Avenue, Palo Alto,; California, 94304, USA. lsu@med.unc.edu
- Pathogenic organisms are frequently attenuated after long-term culture in vitro. The mechanisms of the attenuation process are not clear, but probably involve mutations of functions required for replication and pathogenicity in vivo. To identify these functions, a direct comparison must be made between attenuated geno
- Primary infections with HIV-1 of women and their offspring in Rwanda: findings of heterogeneity at seroconversion, coinfection, and recombinants of HIV-1 subtypes A and C.
- Virology. 1997 Jan 6;227(1):63-76. Unique Identifier : AIDSLINE MED/97167518
- Kampinga GA; Simonon A; Van de Perre P; Karita E; Msellati P; Goudsmit J; Academic Medical Center, University of Amsterdam, Amsterdam, 1105 AZ,; The Netherlands.
- Variation in HIV-1 genomic RNA was studied in seroconversion samples from mother-child pairs from a Rwandan cohort. The mothers (n = 8) were heterosexually infected and their children n = 6) were vertically infected by breast milk. Five of the children seroconverted within the same 3-month period as did their mothers.
- Inhibition of HTLV-I induction and virus-induced syncytia formation by oligodeoxynucleotides.
- Virus Genes. 1996;12(3):205-17. Unique Identifier : AIDSLINE MED/97037711
- Miyano-Kurosaki N; Koyanagi Y; Mizuguchi M; Ohki S; Makino K; Yamamoto N; Department of Microbiology, Tokyo Medical and Dental University,; School of Medicine, Japan.
- HTLV-I is an exogenous human retrovirus that is a causative agent of adult T cell leukemia (ATL). In addition to the structural genes (gag, pol and env), a gene termed pX is postulated to be associated with leukemogenesis in ATL. Since no effective chemotherapy is currently available, it is important to find suitable
- Specific binding of polypyrimidine tract binding protein and hnRNP A1 to HIV-1 CRS elements.
- Virus Genes. 1996;12(3):275-85. Unique Identifier : AIDSLINE MED/97037718
- Black AC; Luo J; Chun S; Bakker A; Fraser JK; Rosenblatt JD
- The human immunodeficiency virus (HIV) Rev and human T-cell leukemia virus (HTLV) Rex proteins regulate viral RNA processing. Both proteins act to overcome the block to viral structural gene expression, at least in part, by reversing the inhibitory effect of intronic RNA sequences, termed cis-acting repressive (CRS) s
- Identification of single and dual infections with distinct subtypes of human immunodeficiency virus type 1 by using restriction fragment length polymorphism analysis.
- Virus Genes. 1996;13(1):69-81. Unique Identifier : AIDSLINE MED/97093420
- Janini LM; Pieniazek D; Peralta JM; Schechter M; Tanuri A; Vicente AC; dela Torre N; Pieniazek NJ; Luo CC; Kalish ML; Schochetman G; Rayfield MA; Division of AIDS, STD, TB, Laboratory Research (DASTLR), Centers for; Disease Control and Prevention, Atlanta, Georgia 30333, USA.
- The simultaneous presence of multiple HIV-1 subtypes has become common in communities with the growth of the pandemic. As a consequence, the potentiality for an increased frequency of HIV-1 mixed infections caused by viruses of distinct subtypes could be expected. Thus, there is a need to estimate the prevalence and g
- [Current problems in the prevention of HIV infection among the troops]
- Voen Med Zh. 1996 Aug;317(8):35-9. Unique Identifier : AIDSLINE MED/97062184
- Kashirin IA
- [Results of an open study for evaluating the effectiveness and tolerance of adjuvant administration of the ISF nutrient program in HIV positive patients]
- Wien Med Wochenschr. 1996;146(18):483-93. Unique Identifier : AIDSLINE MED/97127229
- Fuchs N; Markolin G; Kuklinski B; Jager R; Zelch N; Gurh I; Schicka G; Neumann K; BioPan Zeitgemasse Ernahrung GmbH & Co KG, Mariapfarr, Osterreich.
- HIV positive patients usually show a gradual deterioration of their general condition and the laboratory key values which are accompanied by the resulting negative effects on their subjective condition. This study showed a very good stabilization of HIV positive patients by using the complex ISF nutrient program over
- Antigen-specific oligoclonal IgG in AIDS-related cytomegalovirus and toxoplasma encephalitis.
- Acta Neurol Scand. 1996 Sep;94(3):215-8. Unique Identifier : AIDSLINE MED/97054767
- Franciotta D; Zardini E; Bono G; Brustia R; Minoli L; Cosi V; Laboratory of Neuroimmunology, IRCCS, Neurological Institute, C.; Mondino, Pavia, Italy.
- We retrospectively studied serum and cerebrospinal fluid (CSF) specimens from AIDS patients with either Cytomegalovirus (2 cases) or Toxoplasma gondii (5 cases) encephalitis. The samples, which had previously proved to be negative for total IgG oligoclonal bands (OCBs), were investigated for antigen-specific OCBs dire
- Cerebrovascular complications of HIV in children.
- AJNR Am J Neuroradiol. 1996 Nov-Dec;17(10):1913-7. Unique Identifier : AIDSLINE MED/97087938
- Shah SS; Zimmerman RA; Rorke LB; Vezina LG; Department of Radiology, Children's Hospital of Philadelphia, PA; 19104, USA.
- Two uncommon but important cerebrovascular manifestations of human immunodeficiency virus (HIV) infection in children are arteritis with formation of fusiform aneurysms and arterial sclerosis with vascular occlusion. We studied the CT and MR imaging features of HIV in two girls and one boy (9 to 18 years old) and comp
- The abusive patient: where do you draw the line? [see comments]
- Am J Nurs. 1997 Feb;97(2):31-5; quiz 36. Unique Identifier : AIDSLINE MED/97178249
- Zollo MB; Derse A; Division of Medical Ethics, University of Utah, Salt Lake City, USA.
- Stability of mood despite HIV illness progression in a group of homosexual men.
- Am J Psychiatry. 1997 Feb;154(2):231-8. Unique Identifier : AIDSLINE MED/97168680
- Rabkin JG; Goetz RR; Remien RH; Williams JB; Todak G; Gorman JM; Department of Psychiatry, College of Physicians and Surgeons, Columbia; University, New York, NY, USA.
- OBJECTIVE: The authors investigated the association between mood status and progression of HIV illness. METHOD: In a research clinic at a university medical center, 112 HIV-positive and 52 HIV-negative homosexual men were enrolled in a 4-year prospective study with semi-annual assessments. The main study measures were
- Assisted suicide for HIV patients [letter; comment]
- Am J Psychiatry. 1997 Feb;154(2):294-5. Unique Identifier : AIDSLINE MED/97168702
- Chochinov HM; Wilson KG
- Intravenous cidofovir for peripheral cytomegalovirus retinitis in patients with AIDS. A randomized, controlled trial.
- Ann Intern Med. 1997 Feb 15;126(4):257-63. Unique Identifier : AIDSLINE MED/97172876
- Lalezari JP; Stagg RJ; Kuppermann BD; Holland GN; Kramer F; Ives DV; Youle M; Robinson MR; Drew WL; Jaffe HS; University of California, San Francisco, USA.
- BACKGROUND: Cytomegalovirus ( CMV ) retinitis is the most common intraocular infection in patients with the acquired immunodeficiency syndrome (AIDS). If left untreated, it may lead to progressive destruction of retinal tissue and blindness. Cidofovir is a nucleot
- Parenteral cidofovir for cytomegalovirus retinitis in patients with AIDS: the HPMPC peripheral cytomegalovirus retinitis trial. A randomized, controlled trial. Studies of Ocular complications of AIDS Research Group in Collaboration with the AIDS Clinical Trials Group.
- Ann Intern Med. 1997 Feb 15;126(4):264-74. Unique Identifier : AIDSLINE MED/97172877
- BACKGROUND: Cytomegalovirus ( CMV ) retinitis is a common infection and a major cause of visual loss in patients with the acquired immunodeficiency syndrome (AIDS). OBJECTIVE: To evaluate intravenous cidofovir as a treatment for CMV retinitis. DESIGN: Two-stage, m
- Fluconazole suspension for oropharyngeal candidiasis unresponsive to tablets [letter]
- Ann Intern Med. 1997 Feb 15;126(4):332-3. Unique Identifier : AIDSLINE MED/97172890
- Martins MD; Rex JH
- Pharmacokinetics of a water-soluble fullerene in rats.
- Antimicrob Agents Chemother. 1996 Oct;40(10):2262-5. Unique Identifier : AIDSLINE MED/97046204
- Rajagopalan P; Wudl F; Schinazi RF; Boudinot FD; Department of Pharmaceutics, College of Pharmacy, University of; Georgia, Athens 30602, USA.
- Fullerenes are the recently discovered third allotropic form of carbon. The biological activities of these compounds are being studied for various purposes. The bis(monosuccinimide) derivative of p p -bis(2-amino-ethyl)-diphenyl-C60 (MSAD-C60) is a water-soluble fullerene derivative. MSAD-C60 has been shown to have an
- Susceptibilities of Candida albicans multidrug transporter mutants to various antifungal agents and other metabolic inhibitors.
- Antimicrob Agents Chemother. 1996 Oct;40(10):2300-5. Unique Identifier : AIDSLINE MED/97046213
- Sanglard D; Ischer F; Monod M; Bille J; Institut de Microbiologie, Centre Hospitalier Universitaire Vaudois,; Lausanne, Switzerland. dsanglar@eliot.unil.ch
- Some Candida albicans isolates from AIDS patients with oropharyngeal candidiasis are becoming resistant to the azole antifungal agent fluconazole after prolonged treatment with this compound. Most of the C. albicans isolates resistant to fluconazole fail to accumulate this antifungal agent, and this has been considere
- Pharmacokinetics of (-)-beta-D-2-aminopurine dioxolane and beta-D-2-amino-6-chloropurine dioxolane and their antiviral metabolite (-)-beta-D-dioxolane guanine in rhesus monkeys.
- Antimicrob Agents Chemother. 1996 Oct;40(10):2332-6. Unique Identifier : AIDSLINE MED/97046219
- Chen H; Boudinot FD; Chu CK; Mcclure HM; Schinazi RF; Department of Pharmaceutics, College of Pharmacy, University of; Georgia, Athens 30602, USA.
- (-)-beta-D-2-Aminopurine dioxolane (APD) and beta-D-2-amino-6-chloropurine dioxolane (ACPD) are recently synthesized dioxolanylpurine nucleoside derivatives being developed as potential prodrugs for the antiviral nucleoside analog (-)-beta-D-dioxolane guanine (DXG). In vitro, APD and ACPD are converted to DXG by xanth
- Potent activity of 2'-beta-fluoro-2',3'-dideoxyadenosine against human immunodeficiency virus type 1 infection in hu-PBL-SCID mice.
- Antimicrob Agents Chemother. 1996 Oct;40(10):2369-74. Unique Identifier : AIDSLINE MED/97046225
- Ruxrungtham K; Boone E; Ford H Jr; Driscoll JS; Davey RT Jr; Lane HC; Laboratory of Immunoregulation, National Institute of Allergy and; Infectious Diseases, Bethesda, Maryland 20892, USA.
- A new antiretroviral agent, 2 -beta-fluoro-2 ,3 -dideoxyadenosine FddA), is an acid-stable compound whose triphosphate form is a potent reverse transcriptase inhibitor with in vitro anti-human immunodeficiency virus (HIV) activity and a favorable pharmacokinetic profile. Severe combined immunodeficiency (SCID) mice re
- Human immunodeficiency virus type 1 drug susceptibility determination by using recombinant viruses generated from patient sera tested in a cell-killing assay.
- Antimicrob Agents Chemother. 1996 Oct;40(10):2404-9. Unique Identifier : AIDSLINE MED/97046231
- Boucher CA; Keulen W; van Bommel T; Nijhuis M; de Jong D; de Jong MD; Schipper P; Back NK; Department of Virology, Eijkman-Winkler Institute, University Hospital; Utrecht, The Netherlands. c.boucher@lab.azu.nl
- A simple approach for the determination of drug susceptibilities by using human immunodeficiency virus type 1 (HIV-1) RNA from the sera of patients is described. HIV-1 RNA was extracted from patient sera, and the 5 part of the reverse transcriptase (RT) gene was transcribed into DNA and amplified in a nested PCR. The
- Prenatal and postpartum pharmacokinetics of stavudine 2',3'-didehydro-3'-deoxythymidine) and didanosine dideoxyinosine) in pigtailed macaques (Macaca nemestrina).
- Antimicrob Agents Chemother. 1996 Oct;40(10):2423-5. Unique Identifier : AIDSLINE MED/97046236
- Odinecs A; Pereira C; Nosbisch C; Unadkat JD; Department of Pharmaceutics, University of Washington, Seattle 98195,; USA.
- Stavudine (5 mg/kg of body weight; n = 7) or didanosine (3.2 mg/kg; n = 4) was administered as an intravenous bolus to pregnant pigtailed macaques (Macaca nemestrina) near term and 4 to 5 weeks postpartum. No significant differences were found between
- Kaposi sarcoma unrelated to human immunodeficiency virus infection: long-term results of radiotherapy [letter; comment]
- Arch Dermatol. 1997 Jan;133(1):107-8. Unique Identifier : AIDSLINE MED/97159045
- Gonzalez-Acosta P; Romero J; de la Torre A; Valcarcel F; Regueiro CA; Magallon R; Aragon G
- Absence of human herpesvirus 8 DNA sequences in patients with immunosuppression-associated dermatofibromas [letter]
- Arch Dermatol. 1997 Jan;133(1):108-9. Unique Identifier : AIDSLINE MED/97159046
- Foreman K; Bonish B; Nickoloff B
- Kaposi sarcoma-associated herpesvirus/human herpesvirus type 8 and Epstein-Barr virus in iatrogenic Kaposi sarcoma [letter]
- Arch Dermatol. 1997 Jan;133(1):109-11. Unique Identifier : AIDSLINE MED/97159047
- Henghold WB 2nd; Purvis SF; Schaffer J; Leonard DG; Giam CZ; Wood GS
- Human herpesvirus 8 sequences are not detected in epithelial tumors from patients receiving transplants [letter]
- Arch Dermatol. 1997 Jan;133(1):111. Unique Identifier : AIDSLINE MED/97159048
- Lebbe C; Tatoud R; Morel P; Calvo F; Euvrard S; Kanitakis J; Faure M; Claudy A
- Detection of human herpesvirus 8 and human T-cell lymphotropic virus type 1 sequences in Kaposi sarcoma [see comments]
- Arch Dermatol. 1997 Jan;133(1):25-30. Unique Identifier : AIDSLINE MED/97159028
- Lebbe C; Agbalika F; de Cremoux P; Deplanche M; Rybojad M; Masgrau E; Morel P; Calvo F; Department of Dermatology, Hopital Saint-Louis, Paris, France.
- BACKGROUND: Ultrastructural studies have shown retroviral particles in Kaposi sarcoma (KS) unrelated to infection with the human immunodeficiency virus (HIV). Recently, DNA sequences from a new herpesvirus, human herpesvirus 8 (HHV-8), were detected in KS tissues. OBJECTIVES: To screen for the presence of HHV-8 sequen
- Kaposi sarcoma, Kaposi sarcoma-associated herpesvirus, and human T-cell lymphotropic virus type 1. What is the current evidence for causality? [editorial; comment]
- Arch Dermatol. 1997 Jan;133(1):83-5. Unique Identifier : AIDSLINE MED/97159035
- Warmuth I; Moore PS
- Detection of herpesvirus-like DNA in HIV-associated and classical Kaposi's sarcoma.
- Arch Dermatol Res. 1996 Jun;288(7):402-4. Unique Identifier : AIDSLINE MED/96415222
- Simon M; Kind P; Kaudewitz P; Graf A; Schirren CG; Raffeld M; Sander CA; Department of Dermatology, Ludwig-Maximilians-Universitat, Munich,; Germany.
- Transtibial prosthesis for a patient with Kaposi's sarcoma lesions on the residual limb.
- Arch Phys Med Rehabil. 1997 Jan;78(1):106-8. Unique Identifier : AIDSLINE MED/97167280
- Ethans KD; Kirby RL; Adderson JA; Department of Medicine, Dalhousie University, Canada.
- A man with acquired immunodeficiency syndrome (AIDS) and widespread Kaposi s sarcoma (KS) presented with a transtibial amputation secondary to foot infection and intractable pain. Several open and draining KS lesions were present on the residual limb. There were two concerns: (1) prescribing a prosthesis to a person w
- Bacillary angiomatosis: microbiology, histopathology, clinical presentation, diagnosis and management.
- Bol Asoc Med P R. 1996 Apr-Jun;88(4-6):46-51. Unique Identifier : AIDSLINE MED/97073746
- Ramirez Ramirez CR; Saavedra S; Ramirez Ronda CH; Infectious Diseases Program, University of Puerto Rico School of; Medicine, San Juan VA Medical Center 00927-5800.
- Bacillary angiomatosis is known to be caused by a rickettsial organism; Rochalimaea henselae. This causative agent has been compared with different microorganisms and clinical conditions that appear in similar settings but that have been clearly differentiated from them; e.i. Cat-scratch disease (Afipia felis), Barton
- Battle against maternal-fetal HIV transmission gaining ground in US.
- Immunol Today. 1997 Jan;18(1):3. Unique Identifier : AIDSLINE MED/97171795
- Immune correlates of protection from HIV infection and AIDS.
- Immunol Today. 1997 Jan;18(1):4-8. Unique Identifier : AIDSLINE MED/97171796
- Heeney JL; Bruck C; Goudsmit J; Montagnier L; Schultz A; Tyrrell D; Zolla-Pazner S; Dept of Virology, Biological Primate Research Centre, Rijswiik, The; Netherlands. heeney@bprc.nl
- Antibodies against HIV-1 from phage display libraries: mapping of an immune response and progress towards antiviral immunotherapy.
- Chem Immunol. 1997;65:18-56. Unique Identifier : AIDSLINE MED/97171699
- Parren PW; Burton DR; Scripps Research Institute. Department of Immunology, La Jolla,; Calif., USA.
- 3rd International Congress on Drug Therapy in HIV Infection. Birmingham, United Kingdom, 3-7 November 1996. Abstracts.
- AIDS. 1996 Nov;10 Suppl 2:S1-59. Unique Identifier : AIDSLINE MED/97186093
- Prevalence of high-risk sex among HIV-positive gay and bisexual men: a longitudinal analysis.
- Am J Prev Med. 1996 Nov-Dec;12(6):472-7. Unique Identifier : AIDSLINE MED/97113947
- Posner SF; Marks G; Department of Psychology, University of Southern California, Los; Angeles, USA.
- INTRODUCTION: This longitudinal study examined the prevalence and demographic correlates of unprotected insertive and receptive anal intercourse among HIV-positive gay and bisexual men who were aware of their serostatus. METHODS: Participants (n = 395), sampled randomly at two HIV outpatient clinics in Los Angeles, co
- Candidate HIV type 1 multideterminant cluster peptide-P18MN vaccine constructs elicit type 1 helper T cells, cytotoxic T cells, and neutralizing antibody, all using the same adjuvant immunization.
- AIDS Res Hum Retroviruses. 1996 Mar 1;12(4):259-72. Unique Identifier : AIDSLINE MED/97063118
- Ahlers JD; Dunlop N; Pendleton CD; Newman M; Nara PL; Berzofsky JA; Molecular Immunogenetics, National Cancer Institute, National; Institute of Health (NIH), Bethesda, Maryland 20892, USA.
- Cytotoxic T lymphocytes and Th1 cells have been suggested to play a critical role in the control of HIV infection. It is therefore considered that a vaccine that induces a strong Th1 response and CTL response would be more efficacious than one that does not in providing protection against infection and progression tow
- Autoantibodies to CD4 in HIV type 1-exposed seronegative individuals.
- AIDS Res Hum Retroviruses. 1996 Mar 1;12(4):273-80. Unique Identifier : AIDSLINE MED/97063119
- Burastero SE; Gaffi D; Lopalco L; Tambussi G; Borgonovo B; De Santis C; Abecasis C; Robbioni P; Gasparri A; Lazzarin A; Celada F; Siccardi AG; Beretta A; San Raffaele Scientific Institute, Milan, Italy.
- The aim of this study was to investigate the presence and the fine specificity of anti-CD4 autoantibodies in seronegative subjects sexually exposed to HIV-1. Anti-CD4 autoantibodies were previously detected in a fraction of HIV-1-seropositive individuals. Whole sera, purified IgG fractions, and supernatants of EBV-tra
- Soluble CD4 induces the binding of human immunodeficiency virus type 1 to cells via the V3 loop of glycoprotein 120 and specific sites in glycoprotein 41.
- AIDS Res Hum Retroviruses. 1996 Mar 1;12(4):281-90. Unique Identifier : AIDSLINE MED/97063120
- Demaria S; Bushkin Y; Laboratory of Molecular Immunology, Public Health Research Institute,; New York 10016, USA.
- We have previously reported that incubation of human immunodeficiency virus type 1 (HIV-1) at 4 degrees C with soluble CD4 (sCD4) does not block but increases the binding of virions to CD4-positive H9 cells. In this study, we investigated the mechanism of this effect. It appears that sCD4 can induce the binding of HIV
- Assembly and immunogenicity of chimeric Gag-Env proteins derived from the human immunodeficiency virus type 1.
- AIDS Res Hum Retroviruses. 1996 Mar 1;12(4):291-301. Unique Identifier : AIDSLINE MED/97063121
- Truong C; Brand D; Mallet F; Roingeard P; Brunet S; Barin F; Laboratoire de Virologie, Centre National de la Recherche Scienifique,; Centre Hospitalier Universitaire Bretonneau, France.
- We evaluated the potential of the precursor Gag protein (Pr55) of the human immunodeficiency virus type 1 (HIV-1) as a carrier for the presentation of envelope epitopes. Recombinant chimeric core-envelope protein-expressing constructs were derived by deletion of regions within the gag gene, especially of regions encod
- Long polymerase chain reaction amplification of heterogeneous HIV type 1 templates produces recombination at a relatively high frequency.
- AIDS Res Hum Retroviruses. 1996 Mar 1;12(4):303-6. Unique Identifier : AIDSLINE MED/97063122
- Yang YL; Wang G; Dorman K; Kaplan AH; Department of Medicine, UCLA School of Medicine, Los Angeles,; California 90024, USA.
- Studies of HIV molecular evolution and pathogenesis have relied on the polymerase chain reaction (PCR) to provide sequence information from infected tissues. Until recently, studies have been constrained by the limited length of fragments that can be reliably amplified. The addition of a thermostable 3 -exonuclease ac
- Forward mutation rate of human immunodeficiency virus type 1 in a T lymphoid cell line.
- AIDS Res Hum Retroviruses. 1996 Mar 1;12(4):307-14. Unique Identifier : AIDSLINE MED/97063123
- Mansky LM; McArdle Laboratory for Cancer Research, University of Wisconsin; Medical School, Madison 53706, USA.
- An in vivo assay was previously developed for detecting forward mutations in human immunodeficiency virus type 1 (HIV-1) in a single cycle of replication. This system uses the lacZalpha peptide gene as a reporter for mutations, and allows for the rates and types of mutations that occur to be determined. The forward mu
- Detection of unintegrated HIV type 1 DNA in cell culture and clinical peripheral blood mononuclear cell samples: correlation to disease stage.
- AIDS Res Hum Retroviruses. 1996 Mar 1;12(4):315-23. Unique Identifier : AIDSLINE MED/97063124
- Nicholson WJ; Shepherd AJ; Aw DW; Department of Medicial Microbiology, University Medical School, The; University of Edinburgh, Scotland, UK.
- This article reports on the development of PCR as a sensitive method of detecting both linear and circular forms of HIV-1 unintegrated viral DNA (UVD). The method was developed in a cell line study designed to follow the sequential synthesis of these forms over time. In all T lymphoid lineage cell lines, the full-leng
- Cytokines and soluble receptor changes in the transition from primary to early chronic HIV type 1 infection.
- AIDS Res Hum Retroviruses. 1996 Mar 1;12(4):325-31. Unique Identifier : AIDSLINE MED/97063125
- Barcellini W; Rizzardi GP; Poli G; Tambussi G; Velati C; Meroni PL; Dalgleish AG; Lazzarin A; Department of Internal Medicine, Infectious Diseases and; Immunopathology, University of Milan, Italy.
- We studied determinants of chronic inflammation and/or immune activation in plasma from patients in the transition from primary to early chronic HIV-1 infection. The following parameters were estimated in seven patients over time: plasma concentrations of soluble CD8 (sCD8), tumor necrosis factor alpha (TNF-alpha), so
- Cupric and ferric ions inactivate HIV.
- AIDS Res Hum Retroviruses. 1996 Mar 1;12(4):333-7. Unique Identifier : AIDSLINE MED/97063126
- Sagripanti JL; Lightfoote MM; Molecular Biology Branch (HFZ-113), Center for Devices and; Radiological Health, Food and Drug Administration, Rockville, Maryland; 20857, USA.
- Human immunodeficiency virus (HIV-1) was inactivated by either cupric or ferric ions when the virus was free in solution and also 3 hr after cell infection. Fifty percent inactivation of cell-free HIV was achieved with Cu(II) at a concentration between 0.16 and 1.6 mM, or by 1.8 to 18 mM Fe(III). Thus, the dose to ina
- The nef gene from a long-term HIV type 1 nonprogressor.
- AIDS Res Hum Retroviruses. 1996 Mar 1;12(4):337-45. Unique Identifier : AIDSLINE MED/97063127
- Premkumar DR; Ma XZ; Maitra RK; Chakrabarti BK; Salkowitz J; Yen-Lieberman B; Hirsch MS; Kestler HW; Department of Molecular Biology, Research Institute, The Cleveland; Clinic Foundation, Ohio 44195, USA.
- We examined the nef gene of HIV-1 in a long-term nonprogressor to look for evidence suggesting an attenuated virus. The nef gene was previously shown to be required for induction of AIDS. Simian immunodeficiency virus (SIV) deleted in nef, while infectious, fails to sustain the high viral loads necessary for the induc
- Mutations in the vpu, env, and nef genes of a syncytium-inducing variant of HIV type 1 JR-CSF that infects a range of T cell lines.
- AIDS Res Hum Retroviruses. 1996 Mar 1;12(4):347-50. Unique Identifier : AIDSLINE MED/97063128
- Klasse PJ; Boyd MT; Weiss RA; Schulz TF; Chester Beatty Laboratories, The Institute of Cancer Research, London,; UK.
- Length polymorphism of the viral protein R of human immunodeficiency virus type 1 strains.
- AIDS Res Hum Retroviruses. 1996 Mar 1;12(4):351-4. Unique Identifier : AIDSLINE MED/97063129
- Ge YC; Wang B; Dwyer DE; Xiang SH; Cunningham AL; Saksena N; HIV/HTLV Laboratory, Department of Virology, Westmead Hospital,; Sydney, Australia.
- [AIDS-related primary central nervous system lymphoma]
- No To Shinkei. 1997 Jan;49(1):19-24. Unique Identifier : AIDSLINE MED/97179644
- Hojo I; Department of Pathology, University of Tokyo, Japan.
- [Neurological manifestations associated with HIV-1 infection]
- No To Shinkei. 1997 Jan;49(1):25-37. Unique Identifier : AIDSLINE MED/97179645
- Kishida S; Department of Neurology, Tokyo Metropolitan Komagome Hospital, Japan.
- [Virology on AIDS and AIDS dementia complex]
- No To Shinkei. 1997 Jan;49(1):39-49. Unique Identifier : AIDSLINE MED/97179646
- Hoshino H; Department of Hygiene, Gunma University School of Medicine, Maebashi,; Japan.
- [Neuropathology of AIDS: opportunistic infections and HIV encephalopathy]
- No To Shinkei. 1997 Jan;49(1):5-17. Unique Identifier : AIDSLINE MED/97179643
- Shintaku M; Department of Pathology, Osaka Red Cross Hospital, Japan.
- Inadequate erythropoietin response to anaemia in HIV patients: relationship to serum levels of tumour necrosis factor-alpha, interleukin-6 and their soluble receptors.
- Br J Haematol. 1997 Feb;96(2):235-9. Unique Identifier : AIDSLINE MED/97180787
- Kreuzer KA; Rockstroh JK; Jelkmann W; Theisen A; Spengler U; Sauerbruch T; Department of Medicine, University of Bonn, Germany.
- Severe anaemia is a frequent complication in advanced HIV infection. In our study we investigated the interaction between cytokine network, HIV infection and erythropoietin (Epo) response with increasing anaemia levels. No correlations could be established between circulating tumour necrosis factor TNF)-alpha and any
- Clonal expansion of Vgamma3/Vdelta3-expressing gammadelta T cells in an HIV-1/2-negative patient with CD4 T-cell deficiency.
- Br J Haematol. 1997 Feb;96(2):266-71. Unique Identifier : AIDSLINE MED/97180793
- Kabelitz D; Hinz T; Dobmeyer T; Mentzel U; Marx S; Bohme A; Arden B; Rossol R; Hoelzer D; Department of Immunology, Paul-Ehrlich-Institute, Langen, Germany.
- Immunological investigations were carried out in an HIV-1/2//HTLV-1-negative patient with CD4 T-cell deficiency 0.357-0.6 x 10(9)/l) and expansion of gammadelta T cells which accounted for 26-42% of peripheral blood lymphocytes during an observation period of 3 years. Flow cytometry analyses with a panel of available
- Idiotype-specific T lymphocytes in monoclonal gammopathies: evidence for the presence of CD4+ and CD8+ subsets.
- Br J Haematol. 1997 Feb;96(2):338-45. Unique Identifier : AIDSLINE MED/97180805
- Yi Q; Eriksson I; He W; Holm G; Mellstedt H; Osterborg A; Department of Medicine, Karolinska Hospital, Stockholm, Sweden.
- Tumour-specific CD4+ T helper (Th) and CD8+ T cytotoxic (Tc) cells may participate in the control and eradication of tumour cells. In the present study, idiotype-specific stimulation of CD4+ and CD8+ blood T cells from patients with monoclonal gammopathy of undetermined significance and patients with untreated multipl
- Human herpesvirus-8/Kaposi's sarcoma-associated herpesvirus in organ transplant patients with immunosuppression.
- Br J Haematol. 1997 Feb;96(2):412-4. Unique Identifier : AIDSLINE MED/97180816
- Alkan S; Karcher DS; Ortiz A; Khalil S; Akhtar M; Ali MA; George Washington University, Washington, D.C. 20037, USA.
- Several recent studies have demonstrated Kaposi s sarcoma-associated herpes virus (KSHV), also known as putative human herpes virus-8 (HHV-8), DNA in various epidemiologic forms of Kaposi s sarcoma (KS), including AIDS-associated, classic, and endemic types. Risk of developing KS in non-HIV-infected immunosuppressed h
- Acute respiratory infections in young children comparative findings in emergency rooms in Accra, (Ghana) and Harare Zimbabwe).
- West Afr J Med. 1996 Jul-Sep;15(3):181-5. Unique Identifier : AIDSLINE MED/97166822
- Dakubo GB; Commey JO; Department of Child Health, University of Ghana Medical School, Accra.
- A descriptive study of the emergency room outcome of Acute Respiratory Infections (ARI) in children aged 0-3 years in the department of Child health of the Korle Bu Teaching Hospital KBTH), Ghana and Parirenyatwa Hospital (PH), Zimbabwe was und
- Induction of apoptosis by protease-defective particle preparations of human immunodeficiency virus type 1 is specific to a subset of U937-derived subclones.
- Int Immunol. 1996 Nov;8(11):1687-97. Unique Identifier : AIDSLINE MED/97098948
- Kameoka M; Kimura T; Zhong Q; Zheng YH; Luftig RB; Ikuta K; Section of Serology, Hokkaido University, Sapporo, Japan.
- Several recent reports support the hypothesis that apoptosis occurring in leukocytes of human immunodeficiency virus type 1 HIV-1)-infected individuals is important in progression to AIDS. Specifically, apoptosis of uninfected bystander cells appears critical in the pathogenesis of disease. Here, we present evidence t
- Subset-specific analysis of calcium fluxes in murine AIDS.
- Int Immunol. 1996 Nov;8(11):1715-27. Unique Identifier : AIDSLINE MED/97098951
- Moutschen M; Trebak M; Greimers R; Colombi S; Boniver J; Department of Pathology, University of Liege, Belgium.
- Infection of susceptible strains of mice with the Duplan strain of murine leukemia viruses induces a syndrome called MAIDS murine acquired immunodeficiency syndrome) characterized by immunodeficiency and lymphoproliferation. In addition to a complete refractoriness of most subsets of lymphocytes to mitogen stimulation
- CD4+ CD45RA+ T cells from adults respond to recall antigens after CD28 ligation.
- Int Immunol. 1996 Nov;8(11):1737-42. Unique Identifier : AIDSLINE MED/97098953
- Pilling D; Akbar AN; Bacon PA; Salmon M; Department of Rheumatology, University of Birmingham, UK.
- The leukocyte common antigen isoforms CD45RA and CD45RO have long been used to discriminate human naive and memory T cells respectively. This model was largely based on the observation that CD45RO+ T cells respond preferentially to and show a higher frequency of precursors specific for recall antigens. However, CD45RA
- A profile of human immunodeficiency virus-infected adolescents receiving health care services at selected sites in the United States.
- J Adolesc Health. 1996 Dec;19(6):401-8. Unique Identifier : AIDSLINE MED/97124058
- Rogers AS; Futterman D; Levin L; D'Angelo L; Pediatric, Adolescent, and Maternal AIDS Branch, National Institute of; Child Health and Human Development, National Institutes of Health,; Bethesda, MD 20892-7510, USA.
- OBJECTIVE: To determine the demographic/clinical profile of human immunodeficiency virus (HIV)-infected adolescents in care at selected sites. METHODS: We mailed surveys requesting prevalence data from physicians in government-funded HIV research and care programs on HIV-infected youth (10-21 years) receiving care. RE
- [Disseminated Mycobacterium genavense infection in patients with HIV infection. Description of 5 cases and review of the literature]
- Enferm Infecc Microbiol Clin. 1996 Apr;14(4):220-6. Unique Identifier : AIDSLINE MED/96266052
- Rodriguez P; March F; Garrigo M; Moreno C; Barrio J; Gurgui M; Sambeat MA; Coll P; Servicio de Microbiologia, Hospital de la Santa Creu i Sant Pau,; Barcelona.
- BACKGROUND. Five cases of disseminated infection by Mycobacterium genavense in patients with HIV infection are reported with a review of the literature. MATERIAL AND METHODS. A description of the clinical, epidemiologic and therapeutic characteristics of five cases are presented. The initial isolation of the microorga
- [Disseminated infection by Mycobacterium scrofulaceum: apropos of 3 cases (see comments)]
- Enferm Infecc Microbiol Clin. 1996 Apr;14(4):258-60. Unique Identifier : AIDSLINE MED/96266059
- Campos-Herrero MI; Rodriguez H; Lluch J; Perdomo M; Perez MC; Gomez E; Unidad de Microbiologia, Hospital Nuestra Senora del Pino, Las Palmas; de Gran Canaria.
- BACKGROUND. Mycobacterium avium-M. Intracellulare complex and Mycobacterium kansasii cause most of nontuberculous mycobacteria infections in AIDS patients in Spain . Mycobacterium scrofulaceum is rarely isolated as a cause of disseminated disease and most of case have been reported b
- [Streptococcus equisimilis as the etiologic agent of endocarditis letter)]
- Enferm Infecc Microbiol Clin. 1996 Apr;14(4):274-6. Unique Identifier : AIDSLINE MED/96266066
- Prada JL; Villanueva JL; Ibarra A; Torre-Cisneros J
- [Pneumothorax in patients with AIDS and tuberculosis (letter)]
- Enferm Infecc Microbiol Clin. 1996 Apr;14(4):278. Unique Identifier : AIDSLINE MED/96266070
- Supervia A; Knobel H; Lopez-Colomes JL; Aguirre A
- Retrovirus-mediated gene transfer of B7-1 and MHC class II converts a poorly immunogenic neuroblastoma into a highly immunogenic one.
- Hum Gene Ther. 1996 Nov 10;7(17):2059-68. Unique Identifier : AIDSLINE MED/97088282
- Heuer JG; Tucker-McClung C; Gonin R; Hock RA; Herman B Wells Center for Pediatric Research, Department of; Pediatrics, Indiana University School of Medicine, Indianapolis,; 46202, USA.
- The T cell co-stimulatory molecule B7-1 was transduced into a poorly immunogenic murine neuroblastoma cell line (Neuro-2a, N-2a) alone or in combination with MHC class II genes to test the ability of these genes to stimulate antitumor immunity. N-2a cells transduced with B7-1 exhibited reduced tumorigenicity, whereas
- Determination of tissue distribution of an intramuscular plasmid vaccine using PCR and in situ DNA hybridization.
- Hum Gene Ther. 1996 Nov 10;7(17):2185-94. Unique Identifier : AIDSLINE MED/97088294
- Winegar RA; Monforte JA; Suing KD; O'Loughlin KG; Rudd CJ; Macgregor JT; Toxicology Laboratory, SRI International, Menlo Park, CA 94025, USA.
- The increasing use of nucleic acid-based therapeutics has created a need for new methods of determining tissue distribution and levels. Radiolabel methods may not always be appropriate because nucleic acids are easily degraded. Quantitation using the polymerase chain reaction (PCR) has the advantage that only continuo
- Gene therapy for adult T cell leukemia using human immunodeficiency virus vector carrying the thymidine kinase gene of herpes simplex virus type 1.
- Hum Gene Ther. 1996 Dec 1;7(18):2203-8. Unique Identifier : AIDSLINE MED/97111508
- Obaru K; Fujii S; Matsushita S; Shimada T; Takatsuki K; Second Department of Internal Medicine, Kumamoto University School of; Medicine, Japan.
- Adult T cell leukemia/lymphoma (ATL) is derived from CD4+ T cells and has a poor prognosis because of its resistance to chemotherapy. To evaluate the effectiveness of gene therapy for ATL, the effect of ganciclovir on ATL cell lines transfected with the thymidine kinase gene of herpes simplex virus type 1 (HSV-TK) was
- Efficacy of antitat gene therapy in the presence of high multiplicity infection and inflammatory cytokines.
- Hum Gene Ther. 1996 Dec 1;7(18):2209-16. Unique Identifier : AIDSLINE MED/97111509
- Lisziewicz J; Sun D; Gallo RC; Ensoli B; Lori F; Research Institute for Genetic and Human Therapy, Gaithersburg, MD; 20879, USA.
- Because human immunodeficiency virus type 1 (HIV-1) infection is characterized by a large number of viral replication cycles and rapid cell turnover in vivo, successful gene therapy requires an approach effective under these conditions. The antitat gene has been proposed for gene therapy because it effectively blocks
- Transfer of a gene encoding the anticandidal protein histatin 3 to salivary glands.
- Hum Gene Ther. 1996 Dec 1;7(18):2255-61. Unique Identifier : AIDSLINE MED/97111514
- O'Connell BC; Xu T; Walsh TJ; Sein T; Mastrangeli A; Crystal RG; Oppenheim FG; Baum BJ; Clinical Investigations and Patient Care Branch, National Institute of; Dental Research, National Institutes of Health, Bethesda, MD 20892,; USA.
- Mucosal candidiasis, the most common opportunistic fungal infection in human immunodeficiency virus (HIV)-infected patients, is an early sign of clinically overt acquired immunodeficiency syndrome (AIDS) and an important cause of morbidity, particularly in HIV-infected children. The appearance of azole-resistant strai
- Two-step gene transfer using an adenoviral vector carrying the CD4 gene and human immunodeficiency viral vectors.
- Hum Gene Ther. 1996 Dec 1;7(18):2281-6. Unique Identifier : AIDSLINE MED/97111517
- Miyake K; Tohyama T; Shimada T; Department of Biochemistry and Molecular Biology, Nippon Medical; School, Tokyo, Japan.
- Human immunodeficiency virus-1 (HIV-1) belongs to the lentivirus subfamily of retroviruses and has several interesting features, including T cell tropism and the ability to infect nondividing cells. Replication-incompetent HIV vectors were developed and were shown to be capable of targeted gene transfer into CD4+T cel
- Asymptomatic shedding of herpes simplex virus from the genital tract: uncertainty and its consequences for patient management. The Herpes Simplex Virus Advisory Panel [editorial]
- Int J STD AIDS. 1996 Jul;7(4):229-32. Unique Identifier : AIDSLINE MED/97030410
- Barton SE; Munday PE; Patel RJ
- A frequent component of the management of patients with genital herpes concerns the possibility of asymptomatic shedding and potential sexual transmission of the virus. Approaches intended to provide supportive counselling and reassurance of patients about these issues need now
- Defining bacterial vaginosis: to BV or not to BV, that is the question [editorial]
- Int J STD AIDS. 1996 Jul;7(4):233-5. Unique Identifier : AIDSLINE MED/97030411
- Hay PE; Taylor-Robinson D
- The history of bacterial vaginosis (BV), now extending over more than 40 years, has been remarkable not only in terms of repeatedly changing the name of the bacterium that we now know as Gardnerella vaginalis but also in relation to what is thought to constitute the condition, what it should be called and how the diag
- AIDS in rural Africa: a paradigm for HIV-1 prevention [editorial]
- Int J STD AIDS. 1996 Jul;7(4):236-43. Unique Identifier : AIDSLINE MED/97030412
- Hudson CP
- Networks of concurrent sexual partnerships may be the primary cause of epidemic spread of HIV-1 in parts of sub-Saharan Africa. This pattern of sexual behaviour increases the likelihood that individuals experiencing primary HIV-1 infection transmit the virus to other persons. Networks of concurrent partnerships are li
- The management of mycobacterial infections in HIV seropositive individuals. Jefferiss Wing Therapeutics and Protocols Group [see comments]
- Int J STD AIDS. 1996 Jul;7(4):244-9; quiz 249-51. Unique Identifier : AIDSLINE MED/97030413
- Fisher M; Tomlinson DR; Coker RJ
- AIDS defining diseases in the UK: the impact of PCP prophylaxis and twelve years of change.
- Int J STD AIDS. 1996 Jul;7(4):252-7. Unique Identifier : AIDSLINE MED/97030414
- Porter K; Fairley CK; Wall PG; Evans BG; Goldberg DJ; Weerasuriya M; Noone A; PHLS AIDS Centre, London, UK.
- We examined all reports of adult AIDS cases made to the 2 national surveillance centres in the UK for changes in AIDS defining conditions between January 1982 and September 1994. Differences and changes among persons diagnosed since January 1988 who had and had not been aware of their HIV infection prior to their AIDS
- Clinical features, outcome and survival from cerebral toxoplasmosis in Edinburgh AIDS patients.
- Int J STD AIDS. 1996 Jul;7(4):258-64. Unique Identifier : AIDSLINE MED/97030415
- Laing RB; Flegg PJ; Brettle RP; Leen CL; Burns SM; Regional Infectious Diseases Unit, City Hospital, Edinburgh, UK.
- Nineteen cases of cerebral toxoplasmosis (CTOX) are reported from a group of Edinburgh AIDS patients. All patients were severely immunodeficient at the time of presentation with CD4 count
- HIV infection among pregnant women in Lindi, Tanzania, 1989-1993.
- Int J STD AIDS. 1996 Jul;7(4):265-8. Unique Identifier : AIDSLINE MED/97030416
- Petry KU; Kingu H; Department of Gynecologic Oncology, University of Hannover, Germany.
- One obstacle to contain the HIV-1 epidemic in the general population in Africa is a lack of knowledge about how it is spread in rural areas. We examined 683 pregnant women in 1989 and 484 in 1993 who attended antenatal clinics in Lindi district, Tanzania to determine changes in t
- Sexually transmitted diseases: a survey of case management in Malawi.
- Int J STD AIDS. 1996 Jul;7(4):269-75. Unique Identifier : AIDSLINE MED/97030417
- Chilongozi DA; Daly CC; Franco L; Liomba NG; Dallabetta G; National AIDS Control Programme, Ministry of Health, Malawi.
- A national survey of sexually transmitted disease (STD) case management was carried out at 39 health care facilities in Malawi in 1994. Fifty-four health care providers were observed managing 150 patients presenting with selected STD syndromes and 103 providers were interviewed. ST
- Efficacy of inosine pranobex oral therapy in subclinical human papillomavirus infection of the vulva: a randomized double-blinded placebo controlled study.
- Int J STD AIDS. 1996 Jul;7(4):276-80. Unique Identifier : AIDSLINE MED/97030418
- Tay SK; Singapore General Hospital, Singapore.
- A randomized double-blind placebo controlled study was carried out to assess the efficacy of inosine pranobex (1 g orally 3 times a day for 6 weeks) in the treatment of symptomatic subclinical human papillomavirus infection of the vulva. In a series of 55 women, 22 patients in the inosine pranobex group and 24 patient
- Men with repeated episodes of gonorrhoea 1990-1992.
- Int J STD AIDS. 1996 Jul;7(4):281-3. Unique Identifier : AIDSLINE MED/97030419
- Sherrard J; Barlow D; Harrison Department, Radcliffe Infirmary, Oxford, UK.
- Patients who acquire repeated infections of gonorrhoea are well described. A study was undertaken of male patients attending a central London clinic in an attempt to identify features of those acquiring repeated infections to facilitate risk reduction strategies. During the 3 years 1990 to 1992, 18.8% of patients cont
- Recurrent bacterial vaginosis--an old approach to a new problem [see comments]
- Int J STD AIDS. 1996 Jul;7(4):284-7. Unique Identifier : AIDSLINE MED/97030420
- Winceslaus SJ; Calver G; Maidstone General Hospital, Kent, UK.
- Bacterial vaginosis (BV) is a common cause of abnormal malodorous vaginal discharge and can be frustrating to manage in its recurrent form. Metronidazole is the standard treatment, but is unacceptable to many women when given repeatedly. Results of treating recurrent BV using a single vaginal washout with 3% hydrogen
- Determination of T-lymphocyte subsets on site in rural Tanzania: results in HIV-1 infected and non-infected individuals.
- Int J STD AIDS. 1996 Jul;7(4):288-91. Unique Identifier : AIDSLINE MED/97030421
- Levin A; Brubaker G; Shao JS; Kumby D; O'Brien TR; Goedert JJ; Strauss KW; Blattner WA; Hannet I; Department of Virology, Medical College of St Bartholomew's Hospital,; London, UK.
- With the FACSCount flow cytometer, counts of CD4, CD8 and CD3 lymphocytes and CD4/CD8 ratios were performed in a rural hospital in Tanzania . A total of 168 subjects (21 HIV-1 seropositive and 147 HIV-1 seronegative) were tested as part of a population-based serosurvey and AIDS ed
- Penile implant as a risk factor for sexually acquired gonococcal and chlamydial urethritis in the elderly.
- Int J STD AIDS. 1996 Jul;7(4):292-4. Unique Identifier : AIDSLINE MED/97030422
- Morgan DJ; Wall R; Richardson P; Colbeck R; Kapembwa M; Department of Genito-Urinary Medicine and Infectious Diseases,; Northwick Park Hospital, Harrow, UK.
- Systemic strongyloidiasis complicating HIV: a promising response to ivermectin.
- Int J STD AIDS. 1996 Jul;7(4):294-6. Unique Identifier : AIDSLINE MED/97030423
- Heath T; Riminton S; Garsia R; MacLeod C; Department of Infectious Diseases, Royal Prince Alfred Hospital,; Sydney, Australia.
- Arsenical pessaries in the successful elimination of metronidazole-resistant Trichomonas vaginalis.
- Int J STD AIDS. 1996 Jul;7(4):296-7. Unique Identifier : AIDSLINE MED/97030424
- Watson PG; Pattman RS; Department of GUM, Newcastle General Hospital, Newcastle upon Tyne,; UK.
- National standards for the management of gonorrhoea.
- Int J STD AIDS. 1996 Jul;7(4):298-300. Unique Identifier : AIDSLINE MED/97030425
- FitzGerald M; Bedford C; National Audit Development Project in Sexual Health, Taunton and; Somerset Hospital, Musgrove Park, UK. Royal College of Physicians,; National Audit Development Programme in Sexual Health.
- National standards for contact tracing in gonorrhoea. Royal College of Physicians, National Audit Development Programme in Sexual Health.
- Int J STD AIDS. 1996 Jul;7(4):301. Unique Identifier : AIDSLINE MED/97030426
- FitzGerald M; Thirlby D; Bell G; Bedford C; National Audit Development Project in Sexual Health, Taunton, UK.
- Atovaquone as prophylaxis for Pneumocystis carinii [letter]
- Int J STD AIDS. 1996 Jul;7(4):302. Unique Identifier : AIDSLINE MED/97030427
- Vilar FJ; McKendrick MW; Nash C
- The importance of transmission of HIV-1 in discordant couples in the population dynamics of HIV-1 infection in rural Africa [letter]
- Int J STD AIDS. 1996 Jul;7(4):302-4. Unique Identifier : AIDSLINE MED/97030428
- Hudson CP
- Sex, lies, and genitourinary medicine [letter]
- Int J STD AIDS. 1996 Jul;7(4):304-6. Unique Identifier : AIDSLINE MED/97030429
- Hudson CP
- Supercritical fluid extraction method development for extraction of an experimental HIV protease inhibitor drug from animal feed.
- J Pharm Biomed Anal. 1997 Jan;15(4):461-8. Unique Identifier : AIDSLINE MED/97111687
- Roston DA; Sun JJ; Searle Research and Development, Skokie, IL 60077, USA.
- Supercritical fluid extraction (SFE) was evaluated as a sample preparation procedure for the recovery of experimental drugs from animal feed preparations that are generated during long-term toxicology studies. A commercially available supercritical fluid extractor was utilized to develop and validate an off-line proce
- Association of natural killer cell immune recovery with a graft-versus-leukemia effect independent of graft-versus-host disease following allogeneic bone marrow transplantation.
- Ann Hematol. 1997 Jan;74(1):1-6. Unique Identifier : AIDSLINE MED/97183641
- Jiang YZ; Barrett AJ; Goldman JM; Mavroudis DA; Bone Marrow Transplantation Unit, NIH, Bethesda, MD 20892-1652, USA.
- There is good evidence that T lymphocytes play an important role in the graft-versus-leukemia (GVL) effect following allogeneic bone marrow transplantation (BMT) for hematologic malignancies. However, the role of natural killer (NK) cells in GVL is less clear. To further investigate a possible association of NK cells
- Validation of a particle enhanced immunoturbidimetric assay for serum beta 2-microglobulin on the Dade aca.
- Eur J Clin Chem Clin Biochem. 1996 Oct;34(10):861-5. Unique Identifier : AIDSLINE MED/97087084
- Newman DJ; Kassai M; Craig AR; Gorman EG; Price CP; Department of Clinical Biochemistry, St Bartholomew's School of; Medicine and Dentistry, London, UK.
- We describe the development and validation of a fully automated homogeneous immunoassay for serum beta 2-microglobulin on the Dade aca clinical analyzer. The assay employs latex enhanced immunoturbidimetry, with an affinity purified polyclonal antibody covalently coupled to a 40 nm latex particle. The assay working ra
- Prevalence of microsporidiosis due to Enterocytozoon bieneusi and Encephalitozoon (Septata) intestinalis among patients with AIDS-related diarrhea: determination by polymerase chain reaction to the microsporidian small-subunit rRNA gene.
- Clin Infect Dis. 1996 Nov;23(5):1002-6. Unique Identifier : AIDSLINE MED/97081550
- Coyle CM; Wittner M; Kotler DP; Noyer C; Orenstein JM; Tanowitz HB; Weiss LM; Department of Medicine, Albert Einstein College of Medicine, Bronx,; New York 10461, USA.
- Microsporidia are emerging as opportunistic pathogens in patients with AIDS. Enterocytozoon bieneusi and Encephalitozoon (Septata) intestinalis have been implicated in enteric infections in AIDS patients with chronic diarrhea, a wasting syndrome, and malabsorption. We used the polymerase chain reaction (PCR) and prime
- Lack of effect of cimetidine on lymphocyte subsets in patients infected with human immunodeficiency virus type 1.
- Clin Infect Dis. 1996 Nov;23(5):1049-54. Unique Identifier : AIDSLINE MED/97081558
- Cohen CJ; Hellinger JA; Day J; Salitsky N; Shevitz A; Zackin R; DeGruttola V; Community Research Initiative of New England, Harvard Community Health; Plan, Brookline, Massachusetts 02146, USA.
- Cimetidine, widely used for peptic ulcer disease, blocks type 2 histamine receptors present on immune cells, including T cells, B cells, and monocytes. As an earlier published study showed evidence of increases in CD4 cell counts due to this drug, we conducted a randomized, placebo-controlled, 8-week trial of oral cim
- Toxoplasmosis of the spinal cord in a patient with AIDS: case report and review.
- Clin Infect Dis. 1996 Nov;23(5):1061-5. Unique Identifier : AIDSLINE MED/97081560
- Vyas R; Ebright JR; Department of Internal Medicine, Wayne State University, Detroit; Medical Center, Michigan, USA.
- We present the case of a patient whose acute myelopathy almost completely resolved with empirical therapy for toxoplasmosis, and we review thirteen previously reported cases of myelopathy thought to have been caused by Toxoplasma gondii in patients with AIDS. The most common symptoms and abnormal physical findings wer
- Cytarabine therapy for progressive multifocal leukoencephalopathy in patients with AIDS.
- Clin Infect Dis. 1996 Nov;23(5):1066-8. Unique Identifier : AIDSLINE MED/97081561
- Moreno S; Miralles P; Diaz MD; Berenguer J; Bernaldo de Quiros JC; Blazquez R; Cosin J; Bouza E; Department of Clinical Microbiology, Hospital General Universitario,; Gregorio Maranon, Madrid, Spain.
- To evaluate the efficacy and safety of intravenous cytarabine in the treatment of AIDS-associated progressive multifocal leukoencephalopathy (PML), we reviewed the charts of all human immunodeficiency virus-infected patients with PML who were seen during a 28-month period at our institution. Patients with biopsy-prove
- Reciprocal interactions between human immunodeficiency virus and hepatitis C virus infections.
- Clin Infect Dis. 1996 Nov;23(5):1117-25. Unique Identifier : AIDSLINE MED/97081569
- Zylberberg H; Pol S; Service d'Hepatologie, Hopital Necker, Paris, France.
- Hepatitis C virus (HCV) and human immunodeficiency virus (HIV) share the same routes of transmission, which explains the high rate of HCV and HIV coinfection (approximately 9%). HIV/HCV coinfection leads to high rates of indeterminate recombinant immunoblot assay patterns and seroreversion; high levels of viral replic
- Seroconversion to human herpesvirus 6 and human herpesvirus 7 among Brazilian children with clinical diagnoses of measles or rubella.
- Clin Infect Dis. 1996 Nov;23(5):1156-8. Unique Identifier : AIDSLINE MED/97081573
- Black JB; Durigon E; Kite-Powell K; de Souza L; Curli SP; Afonso AM; Theobaldo M; Pellett PE; Centers for Disease Control and Prevention, Atlanta, Georgia.
- We collected acute-phase and convalescent-phase serum samples from Brazilian patients who presented with exanthem of unknown origin and evaluated these samples by means of an immunoblot assay for seroconversion to human herpesvirus 6 (HIV-6) or human herpesvirus 7 (HIV-7). Measles or rubella had been clinically diagno
- Infection with human immunodeficiency virus does not influence the clinical severity of scrub typhus.
- Clin Infect Dis. 1996 Nov;23(5):1168-70. Unique Identifier : AIDSLINE MED/97081577
- Kantipong P; Watt G; Jongsakul K; Choenchitra C; Department of Medicine, Chiangrai Regional Hospital, Thailand.
- Infection by Orientia (formerly Rickettsia) tsutsugamushi causes scrub typhus, a severe febrile disease common in Asia. Both scrub typhus and AIDS are prevalent in northern Thailand . Therefore, we prospectively investigated the impact of infection due to human immunodeficiency vi
- Tuberculous rheumatism (Poncet's disease) in a patient infected with human immunodeficiency virus.
- Clin Infect Dis. 1996 Nov;23(5):1179-80. Unique Identifier : AIDSLINE MED/97081583
- Lesprit P; Lafaurie M; Liote F; Decazes JM; Modai J; Service de Maladies Infectieuses, Hopital Saint Louis, Paris, France.
- Clostridium paraputrificum bacteremia in a patient with AIDS and Duodenal Kaposi's sarcoma.
- Clin Infect Dis. 1996 Nov;23(5):1183-4. Unique Identifier : AIDSLINE MED/97081586
- Nerad JL; Pulvirenti JJ; Department of Medicine, Cook County Hospital, Chicago, Illinois, USA.
- Isolation of Candida norvegensis from clinical specimens: four case reports.
- Clin Infect Dis. 1996 Nov;23(5):1185-7. Unique Identifier : AIDSLINE MED/97081588
- Hood SV; Moore CB; Denning DW; Department of Infectious Diseases and Tropical Medicine, North; Manchester General Hospital, United Kingdom.
- Hypothermia following the intravenous administration of amphotericin B.
- Clin Infect Dis. 1996 Nov;23(5):1187-8. Unique Identifier : AIDSLINE MED/97081589
- Barlows TG 3rd; Luber AD; Jacobs RA; Guglielmo BJ; Department of Clinical Pharmacy, School of Pharmacy, San Francisco,; California, USA.
- Cryptococcal choroiditis in a patient with AIDS: case report and review.
- Clin Infect Dis. 1996 Nov;23(5):1193-4. Unique Identifier : AIDSLINE MED/97081594
- Gandhi SA; McMeeking AA; Friedberg D; Holzman RS; Department of Medicine, New York University Medical Center, New York,; USA.
- Rifabutin prevents campylobacter infection in patients with AIDS [letter; comment]
- Clin Infect Dis. 1996 Nov;23(5):1197-8. Unique Identifier : AIDSLINE MED/97081597
- Pulik M; Leturdu F; Lionnet F; Genet P; Petitdidier C; Touahri T
- How contagious is tuberculosis?
- Clin Infect Dis. 1996 Nov;23(5):954-62. Unique Identifier : AIDSLINE MED/97081542
- Sepkowitz KA; Infectious Disease Service, Memorial Sloan-Kettering Cancer Center,; New York Hospital-Cornell Medical Center, New York 10021, USA.
- Azithromycin activity against Mycobacterium avium complex lung disease in patients who were not infected with human immunodeficiency virus.
- Clin Infect Dis. 1996 Nov;23(5):983-9. Unique Identifier : AIDSLINE MED/97081547
- Griffith DE; Brown BA; Girard WM; Murphy DT; Wallace RJ Jr; Department of Medicine, University of Texas Health Center, Tyler; 75710, USA.
- We initiated a prospective trial of an azithromycin-containing regimen for the treatment of human immunodeficiency virus-negative patients with Mycobacterium avium complex (MAC) lung disease; the initial 4 months of therapy were with azithromycin (600 mg/d) alone. The primary study endpoint was microbiological respons
- Herpes zoster and progression to AIDS in a cohort of individuals who seroconverted to human immunodeficiency virus. Italian HIV Seroconversion Study.
- Clin Infect Dis. 1996 Nov;23(5):990-5. Unique Identifier : AIDSLINE MED/97081548
- Alliegro MB; Dorrucci M; Pezzotti P; Rezza G; Sinicco A; Barbanera M; Castelli F; Tarantini G; Petrucci A; Centro Operativo AIDS, Istituto Superiore di Sanita, Rome, Italy.
- A prospective study of 1,198 individuals who seroconverted to human immunodeficiency virus (HIV) was conducted to estimate the incidence and determinants of herpes zoster and to determine whether herpes zoster can accelerate the progression to AIDS. Herpes zoster was diagnosed for 48 individuals (4%). After adjusting
- Fluconazole therapy for histoplasmosis. The National Institute of Allergy and Infectious Diseases Mycoses Study Group.
- Clin Infect Dis. 1996 Nov;23(5):996-1001. Unique Identifier : AIDSLINE MED/97081549
- McKinsey DS; Kauffman CA; Pappas PG; Cloud GA; Girard WM; Sharkey PK; Hamill RJ; Thomas CJ; Dismukes WE; Infectious Diseases Associates of Kansas City, Missouri, USA.
- We assessed the efficacy of oral fluconazole (200-800 mg daily) in the treatment of non-life-threatening acute pulmonary histoplasmosis, chronic pulmonary histoplasmosis, or disseminated histoplasmosis in patients without human immunodeficiency virus infection. Of 27 evaluable patients, two had progressive acute pulmo
- Conformation of sulfoquinovosyldiacylglycerol bound to a magnetically oriented membrane system.
- Biophys J. 1996 Nov;71(5):2573-82. Unique Identifier : AIDSLINE MED/97070669
- Howard KP; Prestegard JH; Department of Chemistry, Yale University, New Haven, Connecticut; 06511, USA.
- The conformation of uniformly 13C-labeled sulfoquinovosyldiacylglycerol (SQDG) is studied in both membrane and solution environments using NMR spectroscopy. Analysis in a membrane-like environment is based on the measurement of dipolar interactions between 13C-13C and 1H-13C spin pairs and on the measurement of 13C ch
- NMR and CD studies on the conformation of a synthetic peptide containing epitopes of the human immunodeficiency virus 1 transmembrane protein gp41.
- Biopolymers. 1996 Mar;38(3):423-35. Unique Identifier : AIDSLINE MED/97063108
- Consonni R; Limiroli R; Longhi R; Manera E; Vecchio G; Ragona L; Siccardi AG; Zetta L; Istituto di Chimica delle Marcromolecole Lab. NMR, Milano, Italy.
- CD and nmr characterizations are reported for the 23-mer peptide CMC3, corresponding to residues 577-599 of gp41, the transmembrane glycoprotein of the human immunodeficiency virus 1. Concentration, temperature, and pH dependencies of CD and nmr spectra are indicative of self-association with a consequent stabilizatio
- The HIV-1 gp120 causes ultrastructural changes typical of apoptosis in the rat cerebral cortex.
- Neuroreport. 1996 Jul 29;7(11):1722-4. Unique Identifier : AIDSLINE MED/97061621
- Bagetta G; Corasaniti MT; Malorni W; Rainaldi G; Berliocchi L; Finazzi-Agro A; Nistico G; Department of Pharmacobiology, University of Calabria at Cosenza,; Italy.
- We used transmission electron microscopy (TEM) and terminal deoxynucleotidyl transferase (TdT)-mediated dUTP-biotin nick end-labelling (TUNEL) techniques to study the neuropathological effects of intracerebroventricular (i.c.v.) injection of recombinant HIV-1 gp 120 in rats. In brain cortical tissue sections from rats
- A potential role for interferon-alpha in the pathogenesis of HIV-associated dementia.
- Brain Behav Immun. 1995 Dec;9(4):366-77. Unique Identifier : AIDSLINE MED/97059532
- Rho MB; Wesselingh S; Glass JD; McArthur JC; Choi S; Griffin J; Tyor WR; Department of Neurology, Johns Hopkins University School of Medicine,; Baltimore, Maryland 21218, USA.
- Previous studies in patients receiving interferon-alpha IFN-alpha) therapy and patients with systemic lupus erythematosus have demonstrated that elevated cerebrospinal fluid CSF) levels of IFN-alpha are associated with cognitive dysfunction. We measured IFN-alpha levels in CSF and blood by ELISA in human immunodeficie
- Distinct expressions of three cytokines by IL-1-stimulated astrocytes in vitro and in AIDS brain.
- Brain Behav Immun. 1995 Dec;9(4):378-88. Unique Identifier : AIDSLINE MED/97059533
- Vitkovic L; Chatham JJ; da Cunha A; Division of Neuroscience and Behavioral Science, National Institute of; Mental Health, National Institutes of Health, Rockville, Maryland; 20857 USA.
- Interleukin-1 (IL-1) is elevated in brain tissue of individuals who died with acquired immunodeficiency syndrome (AIDS) and other diseases where this cytokine likely stimulates reactive astrocytosis. IL-1 stimulates, among others, production of interleukin-6 (IL-6), granulocyte macrophage colony-stimulating factor (GM
- Autoantibodies and immunoglobulins in atomic bomb survivors with human T-lymphotropic virus type I.
- Intern Med. 1996 Aug;35(8):624-8. Unique Identifier : AIDSLINE MED/97050008
- Ohishi K; Shibata Y; Nakamura T; Tsujihata M; Akahoshi M; Matsuo T; Tomonaga M; Nagataki S; Shimaoka K; Radiation Effects Research Foundation, Nagasaki.
- The association of human T-lymphotropic virus type I (HTLV-I) with autoimmune disorders was investigated on the basis of prevalence of antinuclear antibody (ANA), rheumatoid factor and anti-thyroglobulin antibody as well as immunoglobulin (Ig) serum level (IgG, IgA, and IgM). The subjects, all atomic bomb survivors, w
- Dealing with patients with HIV infection. Isolation is impractical and unnecessary [letter]
- BMJ. 1997 Jan 18;314(7075):220. Unique Identifier : AIDSLINE MED/97174787
- Curtis H
- Dealing with patients with HIV infection. Such bigotry should not have been published [letter]
- BMJ. 1997 Jan 18;314(7075):220-1. Unique Identifier : AIDSLINE MED/97174788
- Walker PP
- Dealing with patients with HIV infection. Eliminating poverty and ignorance is the solution [letter]
- BMJ. 1997 Jan 18;314(7075):221. Unique Identifier : AIDSLINE MED/97174789
- Fox EF; Smith NA; Bradbeer CS
- Dealing with patients with HIV infection. Few authors have the courage to stand up and be counted [letter]
- BMJ. 1997 Jan 18;314(7075):221. Unique Identifier : AIDSLINE MED/97174790
- Daggett P
- Retroviruses and human cancers.
- Eur J Cancer Prev. 1996 Oct;5(5):405. Unique Identifier : AIDSLINE MED/97127506
- de The G; Epidemiology of Oncogenic Viruses Unit, Institut Pasteur, Paris,; France.
- HTLV-I and cancers in tropical countries.
- Eur J Cancer Prev. 1996 Oct;5(5):409-10. Unique Identifier : AIDSLINE MED/97127509
- Moreau JP; Gessain A; de The G; Institut Pasteur de Dakar, Senegal. France.
- HIV-1 and Kaposi's sarcoma.
- Eur J Cancer Prev. 1996 Oct;5(5):410-2. Unique Identifier : AIDSLINE MED/97127510
- Ensoli B; Cafaro A; Laboratory of Virology, Istituto Superiore di Sanita, Rome, Italy.
- Three-dimensional solution structure of the HIV-1 protease complexed with DMP323, a novel cyclic urea-type inhibitor, determined by nuclear magnetic resonance spectroscopy.
- Protein Sci. 1996 Mar;5(3):495-506. Unique Identifier : AIDSLINE MED/97022126
- Yamazaki T; Hinck AP; Wang YX; Nicholson LK; Torchia DA; Wingfield P; Stahl SJ; Kaufman JD; Chang CH; Domaille PJ; Lam PY; Molecular Structural Biology Unit, NIDR, Bethesda, Maryland 20892,; USA.
- The three-dimensional solution structure of the HIV-1 protease homodimer, MW 22.2 kDa, complexed to a potent, cyclic urea-based inhibitor, DMP323, is reported. This is the first solution structure of an HIV protease/inhibitor complex that has been elucidated. Multidimensional heteronuclear NMR spectra were used to ass
- Development of a method of thymocyte differentiation of bone marrow-enriched CD34+CD38- cells in postnatal allogeneic cultured thymic epithelia to evaluate immunodeficiency disorders.
- Stem Cells. 1996 Nov;14(6):702-13. Unique Identifier : AIDSLINE MED/97103689
- Knutsen AP; Roodman ST; Ruiz ME; Mueller KR; Bouhasin JD; Pediatric Research Institute, St. Louis University Health Sciences; Center, Missouri 63110, USA.
- An in vitro model of CD34+CD38- stem cell (SC) differentiation in postnatal cultured thymic epithelia fragment (CTEF) cocultures is described. Sequential phenotypic analysis of the progeny of the SC-CTEF demonstrated predominantly thymocytes and minor populations of promyelocytes, monocytes and natural killer cells. T
- National Surveillance of Occupational Exposure to the Human Immunodeficiency Virus.
- Can Commun Dis Rep. 1996 Apr 1;22(7):52-4. Unique Identifier : AIDSLINE MED/97162397
- Deschamps L; Archibald C; Division of HIV Epidemiology Research, Bureau of HIV/AIDS and STD,; Ottawa, Ontario.
- Protocols help protect against getting HIV--but you have to use them.
- Can Commun Dis Rep. 1996 Apr 1;22(7):54; discussion 54-6. Unique Identifier : AIDSLINE MED/97162398
- Antibody-producing effects in mice by synthetic immunoactive lipopeptides with the conjugated amino acid sequence of gp120 in human immunodeficiency virus.
- Biol Pharm Bull. 1996 Oct;19(10):1271-4. Unique Identifier : AIDSLINE MED/97070569
- Shimizu T; Iwamoto Y; Yanagihara Y; Ryoyama K; Maruyama Y; Achiwa K; University of Shizuoka, School of Pharmaceutical Sciences, Japan.
- To induce peptide-specific antibodies in mice, as a model for vaccination against human immunodeficiency virus (HIV), lipopeptide analogs conjugated with three repeating units KAB-112; designated as gp120-peptide) of a part Gly-Pro-Gly-Arg-Ala-Phe) of the amino acid sequences of the V3 loop region in gp120 of HIV were
- AIDS and severe HIV disease: combined predictions for the United Kingdom to 1999.
- Commun Dis Rep CDR Rev. 1996 Dec 6;6(13):R192-4. Unique Identifier : AIDSLINE MED/97144883
- Allardice G; Hughes G
- The number of HIV infections prevalent in the United Kingdom (UK) at the end of 1994 have been estimated. Estimates of the future annual incidence and prevalence of AIDS and severe HIV disease have been calculated for the UK by combining recently published projections for Scotland with
- Random fragment libraries using yeast expression plasmid.
- Methods Mol Biol. 1996;66:241-55. Unique Identifier : AIDSLINE MED/97118878
- Benichou S; Inchauspe G; Institut Cochin de Genetique Moleculaire, Paris, France.
- Epitope mapping antibody-antigen complexes by nuclear magnetic resonance spectroscopy.
- Methods Mol Biol. 1996;66:25-37. Unique Identifier : AIDSLINE MED/97118859
- Kustanovich I; Zvi A; Department of Structural Biology, Weizmann Institute of Science,; Rehovot, Israel.
- [Health education--knowledge and sources of information about acquired immunodeficiency or AIDS]
- Rev Lat Am Enfermagem. 1996 Jul;4(2):61-71. Unique Identifier : AIDSLINE MED/97056282
- Westrupp MH; Boell Pimentel CP; Berger Salema Coelho E; Caetano JC; de Souza AN
- Questionnaires were answered by 151 students, 10 to 19 years old, from an elementary, Jr. and Senior-high State School in Florianopolis, State of Santa Catarina- Brazil . The objectives were: to identify information sources; transmission mechanisms; prevention forms and the interest
- [The antimicrobial activity of a new wound-healing compound ointment]
- Mikrobiol Z. 1996 May-Jun;58(3):78-82. Unique Identifier : AIDSLINE MED/97112171
- Iakushchenko VA; Biriukova SV; Dziuban NF; Piminov AF; Volianskii IuL; Prokopenko TS
- Drug composition containing polyethyleneoxide PEO-400 and PEO-1500 (8:2), antimicrobe agent-chloramphenical as well as new antiinflammatory mean of plant origin EOL in concentration of 5% has been created. Introduction of EOL to the composition of the drug under elaboration permitted decreasing chloramphenicol concent
- [The validation of the possible use of monosugars and 6-azacytidine for the elimination of Mollicutes associated with HIV/AIDS from the human urogenital tract]
- Mikrobiol Z. 1996 Sep-Oct;58(5):80-5. Unique Identifier : AIDSLINE MED/97146136
- Skrypal' IH; Onyshchenko AM; Tokovenko IP; Malynovs'ka LP; Panchenko LP; Havrylko LO; Shalamai AS; Aleksieieva IV
- A search for the methods new in principle which should block and eliminate AIDS-associated mycoplasmas was carried out. This work was conducted in two ways: 1) inhibition of vital activity of Mycoplasma fermentans PG-18 and Acholeplasma laidlawii PG-8 by 6-azacytidine; 2) establishment of carbohydrate composition of r
- [The properties of HIV-1 isolates and their relation to the epidemic process of HIV infection in Ukraine]
- Mikrobiol Z. 1996 Sep-Oct;58(5):86-9. Unique Identifier : AIDSLINE MED/97146137
- Frolov AF
- We have isolated 29 HIV-1 variants from HIV-1 infected men, 83.3% of these variants having properties Slow/Low and 16.7% belonging to Rapid/High type. The variants of Slow/Low type are of low biological and infective activity. We suppose their properties to correlate with slow HIV-1 infection distributing in
- Antiseptic myramistin possesses the strong anti-HIV properties.
- Mikrobiol Z. 1996 Sep-Oct;58(5):90-2. Unique Identifier : AIDSLINE MED/97146138
- Kryvorutchenko IuL; Kryvoshein IuS; Andronovs'ka IB; Marennykova SS; Stepanova LH; Nosyk DN; Kalnina LB; Rud'ko AP; Department of Microbiology, Crimean Medical Institute, Simferopol.
- The anti-HIV properties of cation detergent myramistin were studied. The dose-dependent slowing down both of the HIV antigens accumulation in supernatants and the virus-dependent cell death was shown at myramistin concentrations 30 micrograms/ml and 50 micrograms/ml in the MT-4 cell line. Simultaneous addition of the
- Viruses in the pathogenesis of Kaposi's sarcoma--a review.
- Biochem Mol Med. 1996 Jun;58(1):1-12. Unique Identifier : AIDSLINE MED/96405199
- Kempf W; Adams V; Department of Dermatology, University Hospital, Zurich, Switzerland.
- Kaposi s sarcoma (KS) is the most frequent malignancy in AIDS patients. Epidemiological studies indicate that a sexually transmitted infections agent other than HIV is involved in the evolution of KS. This KS agent may induce a cascade of cytokines which promote the development of the tumor in an autocrine and parac
- IGF-I does not mediate T-lymphoblast colony formation in response to estradiol, testosterone, 1,25(OH)2 vitamin D3, and triiodothyronine: studies in control and pygmy T-cell lines.
- Biochem Mol Med. 1996 Oct;59(1):72-9. Unique Identifier : AIDSLINE MED/97057868
- Geffner ME; Bersch N; Scott M; Bailey RC; Golde DW; Department of Pediatrics, University of California at Los Angeles; 90095-1752, USA.
- The mechanism by which estradiol, testosterone, 1,25(OH)2 vitamin D3, and triiodothyronine promote tissue growth is unknown, although, in some tissues, a role for local IGF-I has been suggested. We previously showed that HTLV-II-transformed T-cell lines from healthy adults augmented basal colony formation in response
- Exploration of the effects of linker chain modifications on anti-HIV activities in a series of cosalane analogues.
- Bioorg Med Chem. 1996 Oct;4(10):1637-48. Unique Identifier : AIDSLINE MED/97085848
- Golebiewski WM; Keyes RF; Cushman M; Department of Medicinal Chemistry and Molecular Pharmacology, School; of Pharmacy and Pharmacal Sciences, Purdue University, West Lafayette,; IN 47907, USA.
- The effects of linker chain modifications were investigated in a series of cosalane analogues. The modifications investigated included: (1) shortening the three-carbon linker chain between the dichlorodisalicylmethane and the cholestane moiety by one carbon atom; (2) lengthening the linker chain by one carbon; (3) hyd
- Hybrid oligonucleotides: synthesis, biophysical properties, stability studies, and biological activity.
- Bioorg Med Chem. 1996 Oct;4(10):1685-92. Unique Identifier : AIDSLINE MED/97085853
- Yu D; Iyer RP; Shaw DR; Lisziewicz J; Li Y; Jiang Z; Roskey A; Agrawal S; Hybridon Inc., Worcester, MA 01605, USA.
- We have designed and synthesized hybrid oligonucleotides 2-5, as analogues of oligodeoxynucleoside phosphorothioates, in an effort to have agents with improved antisense activity with reduced phosphorothioate content. The hybrid oligonucleotides contain segments of 2 -O-methyl ribonucleoside phosphoric diesters and
- Stereoselective syntheses of substituted pterocarpans with anti-HIV activity, and 5-aza-/5-thia-pterocarpan and 2-aryl-2,3-dihydrobenzofuran analogues.
- Bioorg Med Chem. 1996 Oct;4(10):1755-69. Unique Identifier : AIDSLINE MED/97085861
- Engler TA; LaTessa KO; Iyengar R; Chai W; Agrios K; Department of Chemistry, University of Kansas, Lawrence 66045, USA.
- Oxygenated pterocarpans and 5-azapterocarpans are prepared utilizing Lewis acid-promoted reactions of 2-alkoxy-1,4-benzoquinones with 2H-chromenes and N-tosyl-1,2-dihydroquinolines, respectively. Similarly, benzannulated analogues are prepared via reactions of 5-alkoxy-1,4-naphthoquinones with chromenes, and related 2
- EON: a component-based approach to automation of protocol-directed therapy.
- J Am Med Inform Assoc. 1996 Nov-Dec;3(6):367-88. Unique Identifier : AIDSLINE MED/97084511
- Musen MA; Tu SW; Das AK; Shahar Y; Section on Medical Informatics, Stanford University School of; Medicine, CA 94305-5479, USA. musen@Stanford.EDU
- Provision of automated support for planning protocol-directed therapy requires a computer program to take as input clinical data stored in an electronic patient-record system and to generate as output recommendations for therapeutic interventions and laboratory testing that are defined by applicable protocols. This pa
- Delayed-type hypersensitivity skin reaction estimated with Multitest CMI in human giardiasis.
- Rocz Akad Med Bialymst. 1996;41(2):239-44. Unique Identifier : AIDSLINE MED/97172575
- Flisiak R; Prokopowicz D; Grzeszczuk A; Wiercinska-Drapalo A; Department of Infectious Diseases, Medical Academy of Bialystok.
- Delayed-type hypersensitivity skin reaction performed with Multitest CMI as an indicator of cell-mediated immunity, has been evaluated among 20 adults with giardiasis. There were no correlation found between Multitest CMI score and clinical course of the disease, but significant correlation was observed in relation to
- Hepatitis C virus RNA quantification in right and left lobes of the liver in patients with chronic hepatitis C.
- J Viral Hepat. 1996 Sep;3(5):239-46. Unique Identifier : AIDSLINE MED/97071078
- Idrovo V; Dailey PJ; Jeffers LJ; Coelho-Little E; Bernstein D; Bartholomew M; Alvarez L; Urdea MS; Collins ML; Schiff ER; Division of Hepatology, University of Miami School of Medicine, FL,; USA.
- Quantification of hepatitis C virus RNA in liver tissue is likely to be useful in the study of the natural history, pathogenesis, progression and treatment of hepatitis C virus-associated liver disease. Quantitative measurements of hepatitis C virus RNA in liver biopsy samples using the branched DNA (bDNA) signal ampl
- Long-term effects of interferon-alpha in five HIV-positive patients with chronic hepatitis B.
- J Viral Hepat. 1996 Sep;3(5):253-60. Unique Identifier : AIDSLINE MED/97071080
- di Martino V; Lunel F; Cadranel JF; Hoang C; Parlier Y; Le Charpentier Y; Opolon P; Service d'Hepato-Gastroenterologie, Groupe hospitalier; Pitie-Salpetriere, Paris, France.
- Chronic hepatitis B viral infection is common in human immunodeficiency virus (HIV) carriers, but the effectiveness of interferon therapy is still unknown. We report the results of a long-term pilot study of five patients, who were infected with HIV and chronic hepatitis B, treated by interferon. Five males co-infecte
- Contraceptives and HIV transmission [letter]
- Nat Med. 1997 Feb;3(2):124. Unique Identifier : AIDSLINE MED/97170947
- Duerr A; Warren D; Smith D; Nagachinta T; Marx PA
- A naturally unbalanced combat [new; comment]
- Nat Med. 1997 Feb;3(2):156-7. Unique Identifier : AIDSLINE MED/97170959
- Zagury D
- Antitumor effect of locally produced CD95 ligand.
- Nat Med. 1997 Feb;3(2):165-70. Unique Identifier : AIDSLINE MED/97170961
- Seino K; Kayagaki N; Okumura K; Yagita H; Department of Immunology, Juntendo University School of Medicine,; Tokyo, Japan.
- Activation of the cell-surface antigen CD95 induces apoptosis of CD95-bearing tumor cells. In this study, we investigated the antitumor effect of locally produced CD95 ligand (CD95L) on CD95-negative tumor cells in vivo. Introduction of CD95L cDNA into murine tumor cells did not affect growth in vitro but caused rejec
- Murine psoriasis-like disorder induced by naive CD4+ T cells.
- Nat Med. 1997 Feb;3(2):183-8. Unique Identifier : AIDSLINE MED/97170964
- Schon MP; Detmar M; Parker CM; Division of Rheumatology and Immunology, Brigham and Women's Hospital,; Boston, Massachusetts 02115, USA.
- Psoriasis is a complex disorder involving alterations of many cell types. Although evidence suggests a T-cell pathogenesis for psoriasis, a primary role of T cells has not been directly demonstrated. Here, we show that reconstitution of scid/scid mice with minor histocompatibility mismatched naive CD4+ T lymphocytes r
- Accommodation of vascularized xenografts: expression of protective genes" by donor endothelial cells in a host Th2 cytokine environment.
- Nat Med. 1997 Feb;3(2):196-204. Unique Identifier : AIDSLINE MED/97170966
- Bach FH; Ferran C; Hechenleitner P; Mark W; Koyamada N; Miyatake T; Winkler H; Badrichani A; Candinas D; Hancock WW; Sandoz Center for Immunobiology, Department of Surgery, New England; Deaconess Hospital, Boston, Massachusetts, USA.
- Organ xenografts under certain circumstances survive in the presence of anti-graft antibodies and complement, a situation referred to as accommodation. We find that the endothelial cells (ECs) in hamster hearts that accommodate themselves in rats express genes, such as A20 and bcl-2, that in vitro protect ECs from a
- Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus [see comments]
- Nat Med. 1997 Feb;3(2):205-11. Unique Identifier : AIDSLINE MED/97170967
- Borrow P; Lewicki H; Wei X; Horwitz MS; Peffer N; Meyers H; Nelson JA; Gairin JE; Hahn BH; Oldstone MB; Shaw GM; Department of Neuropharmacology, Scripps Research Institute, La Jolla,; California 92037, USA.
- The HIV-1-specific cytotoxic T lymphocyte (CTL) response is temporally associated with the decline in viremia during primary HIV-1 infection, but definitive evidence that it is of importance in virus containment has been lacking. Here we show that in a patient whose early CTL response was focused on a highly immunodom
- Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS.
- Nat Med. 1997 Feb;3(2):212-7. Unique Identifier : AIDSLINE MED/97170968
- Goulder PJ; Phillips RE; Colbert RA; McAdam S; Ogg G; Nowak MA; Giangrande P; Luzzi G; Morgan B; Edwards A; McMichael AJ; Rowland-Jones S; Nuffield Department of Clinical Medicine, University of Oxford, UK.
- The precise role played by HIV-specific cytotoxic T lymphocytes CTL) in HIV infection remains controversial. Despite strong CTL responses being generated during the asymptomatic phase, the virus persists and AIDS ultimately develops. It has been argued that the virus is so variable, and the virus turnover so great tha
- A new approach to investigating the relationship between productive infection and cytopathicity in vivo.
- Nat Med. 1997 Feb;3(2):218-21. Unique Identifier : AIDSLINE MED/97170969
- Reinhart TA; Rogan MJ; Viglianti GA; Rausch DM; Eiden LE; Haase AT; Department of Microbiology, University of Minnesota Medical School,; Minneapolis 55455, USA.
- We describe a novel experimental approach to analyzing virus-host relationships and potential mechanisms of cytopathicity in vivo in simian immunodeficiency virus (SIV) infections. Progressive destruction of lymphoid tissue in the course of infection by SIV or human immunodeficiency virus (HIV) accompanies the loss of
- Polypharmacy and the treatment of HIV/AIDS.
- J Am Pharm Assoc (Wash). 1996 Dec;NS36(12):722a-722e. Unique Identifier : AIDSLINE MED/97145087
- Bretzel R; Boeth J; Fairfax-Prince William Hematology/Oncology, Annandale, Va., USA.
- Effect of zidovudine (AZT) on the structure and function of rat skeletal muscle.
- Can J Physiol Pharmacol. 1996 Jun;74(6):679-86. Unique Identifier : AIDSLINE MED/97066298
- Engbretson BG; Department of Liberal Arts and Sciences, State University of New York,; Syracuse 13210, USA.
- The role of the anti-HIV agent zidovudine (ZDV = AZT ) in the generation of mitochondrial myopathies and subsequent skeletal muscle contractile deficiencies was evaluated in male rats given ZDV in drinking water (1 mg/mL). After 6 weeks, there was no d
- HEMOCO: a French prospective study of hemophiliacs infected by human immunodeficiency virus type 1 (HIV-1).
- Hematol Cell Ther. 1996 Apr;38(2):193-8. Unique Identifier : AIDSLINE MED/97085928
- Boufassa F; Carre N; Deveau C; Sultan Y; Gazengel C; Blanc A; Peynet J; Ramirez D; Meyer L; Unite INSERM U-292, Hopital de Bicetre, Le Kremlin-Bicetre, France.
- HEMOCO is a multicenter prospective cohort set up in 1989 to monitor 407 French hemophiliacs infected by HIV-1 and recruited in 4 hemophilia treatment centers in the Paris region. As of 15 July 1995, 42% of the patients in the cohort had developed stage B HIV disease and 29% stage C disease (AIDS); 23.1% of the patien
- Gene therapy for HIV infection.
- Hematol Cell Ther. 1996 Apr;38(2):211-3. Unique Identifier : AIDSLINE MED/97085934
- Calenda V; Leissner P; Marigliano M; Mehtali M; Transgene S.A., Strasbourg, France.
- Medicaid reform.
- J Soc Pediatr Nurs. 1996 Apr-Jun;1(1):43-5. Unique Identifier : AIDSLINE MED/97108829
- Villarruel AM; Ekegren K; McClowry S; Perkins MT; Noonan NA; School of Nursing, University of Pennsylvania, USA.; villarr@pobox.upenn.edu
- New protein and PCR markers RAK for diagnosis, prognosis and surgery guidance for breast cancer.
- Cancer Lett. 1997 Jan 15;112(1):93-101. Unique Identifier : AIDSLINE MED/97180956
- Rakowicz-Szulczynska EM; Markowski M; Mackiewicz A; Karczewska A; Snyder W; McIntosh DG; Kapcinska M; Smith ML; Department of Obstetrics and Gynecology, University of Nebraska Eppley; Cancer Center, Omaha, USA.
- Breast cancer antigens RAK-p120, -p42, -p25 were detected in 100% of breast cancer cases tested (71 cases). Only 10% of adjacent tissue cases tested positive for all three cancer antigens, and 17.5% of the cases tested positive for two antigens only. Eighty-five percent of histologically normal breast tissue samples,
- Human T lymphocyte activation in the presence of acute myelogenous leukaemia blasts: studies of allostimulated interferon-gamma secretion.
- Cancer Immunol Immunother. 1996 Dec;43(5):275-82. Unique Identifier : AIDSLINE MED/97176965
- Bruserud O; Mentzoni L; Foss B; Bergheim J; Berentsen S; Nesthus I; Medical Department B, University of Bergen, Norway.
- Normal peripheral blood mononuclear cells (PBMC responders) were cultured together with non-irradiated allogeneic PBMC (more than 95% leukaemia blasts) derived from patients with acute leukaemia referred to as leukaemic PBMC stimulators). Cytokine secretion was determined as cytokine concentrations in supernatants. Bo
- Synthesis and antiviral activity of 6-chloropurine arabinoside and its 2'-deoxy-2'-fluoro derivative.
- Chem Pharm Bull (Tokyo). 1996 Dec;44(12):2331-4. Unique Identifier : AIDSLINE MED/97150106
- Maruyama T; Sato Y; Oto Y; Takahashi Y; Snoeck R; Andrei G; Witvrouw M; De Clercq E; Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Japan.
- 6-Chloropurine arabinoside (3a) was obtained by treatment of the 2 -O-acetylated congener (2) with ammonia in methanol. The 3 ,5 -di-O-tritylated riboside (6) was allowed to react with diethylaminosulfur trifluoride (DAST) in the presence of pyridine to give the 2 -deoxy-2 -fluoroarabinoside (7), from which 6-chloro-9
- Articles on AIDS in major Japanese newspapers.
- Bull Tokyo Med Dent Univ. 1996 Dec;43(4):75-7. Unique Identifier : AIDSLINE MED/97183653
- Hayashi Y; Nakayama E; Moriguchi H; Sato C; Division of Health Science, School of Allied Health Sciences, Tokyo; Medical and Dental University.
- People in general obtain knowledge about AIDS through the mass media. It is interesting to know how newspapers have dealt with AIDS in recent years, since newspapers are the most important mass media. The number of articles on AIDS from 1981 to 1994 was investigated in three major Japanese newspapers (Asahi, Yomiuri,
- Lysosomal hydrolases in serum from human immunodeficiency virus-infected patients.
- Clin Chim Acta. 1996 Nov 15;255(1):57-65. Unique Identifier : AIDSLINE MED/97084069
- Costanzi E; Beccari T; Francisci D; Orlacchio A; Tassi C; Department of Cellular and Molecular Biology, University of Perugia,; Italy.
- beta-Hexosaminidase isoenzymes were separated by DEAE-cellulose chromatography in the serum of 23 patients infected with human immunodeficiency virus at different stage of the disease. Forms corresponding to hexosaminidase B, I and A were present in pathological sera. There is an increase in the percentage of hexosami
- Effect of HIV status on chest radiographic and CT findings in patients with tuberculosis.
- Clin Radiol. 1997 Jan;52(1):31-5. Unique Identifier : AIDSLINE MED/97174917
- Haramati LB; Jenny-Avital ER; Alterman DD; Department of Radiology, Albert Einstein College of Medicine, Bronx,; New York 10461, USA.
- AIM: To compare the chest radiographic and chest CT findings of tuberculosis according to HIV status. PATIENTS AND METHODS: Ninety-eight HIV-tested patients with cultures positive for Mycobacterium tuberculosis (Mtb) between January 1991 and December 1993 whose clinical charts and radiographic records were available f
- Immunophenotyping of peripheral blood mononuclear cells collected by cytotoxic and cytotoxic/G-CSF mobilization.
- Clin Lab Haematol. 1996 Sep;18(3):181-5. Unique Identifier : AIDSLINE MED/97093925
- Kubota A; Nagafuji K; Harada M; Otsuka T; Harada N; Eto T; Takamatsu Y; Fukuda T; Shimoda K; Inaba S; Okamura S; Niho Y; First Department of Internal Medicine, Kyushu University Hospital,; Fukuoka, Japan.
- We investigated surface immunophenotypes of peripheral blood mononuclear cells (PBMC) collected by cytotoxic and cytotoxic/G-CSF mobilization of peripheral blood stem cells PBSC) from 38 patients with haematological malignancies in complete remission who underwent consolidation chemotherapy. PBMC were collected by leu
- Overview of pulmonary complications.
- Clin Chest Med. 1996 Dec;17(4):621-31. Unique Identifier : AIDSLINE MED/97168775
- Rosen MJ; Division of Pulmonary and Critical Care Medicine, Beth Israel Medical; Center, New York, New York, USA.
- Pulmonary diseases continue to be important causes of illness and death in patients with HIV infection, but changes in therapy and demographics of HIV-infected populations are changing their manifestations. The risk of developing specific disorders is related to the area of residence, degree of immunosuppressions, HIV
- Immunologic effects of HIV in the lung.
- Clin Chest Med. 1996 Dec;17(4):633-45. Unique Identifier : AIDSLINE MED/97168776
- Agostini C; Semenzato G; Department of Clinical and Experimental Immunology, Padua University; School of Medicine, Padova, Italy.
- This article covers a selected group of topics dealing with the contribution of lung immunocompetent cells in the host defense mechanisms against HIV. These include recent findings suggesting that bidirectional signals between alveolar macrophages and pulmonary cytotoxic T lymphocytes define regulatory networks, which
- Treatment of HIV infection and its complications.
- Clin Chest Med. 1996 Dec;17(4):647-63. Unique Identifier : AIDSLINE MED/97168777
- Polsky B; Infectious Disease Service, Memorial Sloan-Kettering Cancer Center,; New York, New York, USA.
- Because the AIDS epidemic continues to grow, there is a sense of urgency to develop new treatment strategies, both for HIV infection and for AIDS-related illnesses. The rapid gathering of basic information related to HIV type 1 biology and opportunistic infections has led to an explosion in physicians ability to diag
- Pneumocystis carinii.
- Clin Chest Med. 1996 Dec;17(4):665-95. Unique Identifier : AIDSLINE MED/97168778
- Levine SJ; Critical Care Medicine Department, National Institutes of Health,; Bethesda, Maryland, USA.
- Improved understanding of Pneumocystis carinii, in particular the widespread use of chemoprophylaxis, has resulted in a declining incidence of infection in patients infected with HIV since the late 1980s. Despite these advances, P. carinii pneumonia continues to represent an important cause of pulmonary disease in HIV
- Mycobacterial complications of HIV infection.
- Clin Chest Med. 1996 Dec;17(4):697-711. Unique Identifier : AIDSLINE MED/97168779
- Chin DP; Hopewell PC; Department of Medicine, University of California, San Francisco,; School of Medicine, USA.
- Tuberculosis is the most common opportunistic infection worldwide and is caused by the only readily transmissible pathogen among persons with HIV infection. If treatment is initiated promptly and is supervised appropriately, cure, fortunately, is highly likely. Isoniazid preventive therapy substantially reduces the ri
- Bacterial pneumonia associated with HIV-1 infection.
- Clin Chest Med. 1996 Dec;17(4):713-23. Unique Identifier : AIDSLINE MED/97168780
- Noskin GA; Glassroth J; Department of Medicine, Northwestern University Medical School,; Chicago, Illinois, USA.
- Bacterial pneumonia remains an important cause of treatable morbidity among HIV-1-infected persons. These pneumonias occur at all CD4 counts but are especially common as the HIV-1 infection progresses. Bronchopneumonia should be considered particularly in the setting of segmental or lobar consolidation associated with
- Fungal pulmonary complications.
- Clin Chest Med. 1996 Dec;17(4):725-44. Unique Identifier : AIDSLINE MED/97168781
- Davies SF; Sarosi GA; Department of Medicine, Hennepin County Medical Center, USA.
- With AIDS has come a new level of T-cell immunosuppression, beyond that previously seen. The impact of the HIV pandemic on the field of fungal infections includes a major increase in the number of serious fungal infections, an increase in the severity of those infections, and even some entirely new manifestations of f
- Viruses and other miscellaneous organisms.
- Clin Chest Med. 1996 Dec;17(4):745-54. Unique Identifier : AIDSLINE MED/97168782
- Wallace JM; Department of Medicine, Olive View-UCLA Medical Center, Sylman, USA.
- Pulmonary infections caused by several types of viruses and other miscellaneous organisms may cause disease in HIV infection. Evidence suggests that pulmonary conditions may result from infections of the lung by HIV itself. Other viruses, most commonly cytomegalovirus , may be prima
- Pulmonary complications of HIV-associated malignancies.
- Clin Chest Med. 1996 Dec;17(4):755-61. Unique Identifier : AIDSLINE MED/97168783
- White DA; Department of Medicine, Memorial Sloan-Kettering Cancer Center, New; York, New York, USA.
- Approximately 25% of patients infected with HIV will develop malignancies, most commonly Kaposi s sarcoma and non-Hodgin s lymphoma. These tumors can involve the lung, causing significant morbidity and mortality. This article discusses the clinical presentation, diagnosis, and treatment of the pulmonary complications
- Lymphocytic interstitial pneumonitis and nonspecific interstitial pneumonitis.
- Clin Chest Med. 1996 Dec;17(4):763-6. Unique Identifier : AIDSLINE MED/97168784
- Schneider RF; Medical Intensive Care Unit, Beth Israel Medical Center, New York, New; York, USA.
- Nonspecific interstitial pneumonitis (NIP) and lymphocytic interstitial pneumonitis (LIP), with or without lymphocytic alveolitis, are poorly understood pulmonary complications of HIV infection. These disorders probably represent a spectrum of lymphoproliferative processes that overlap, rather than distinct illnesses.
- Approach to the patient with pulmonary disease.
- Clin Chest Med. 1996 Dec;17(4):767-85. Unique Identifier : AIDSLINE MED/97168785
- Vander Els NJ; Stover DE; Department of Medicine, Cornell University Medical College, New York,; New York, USA.
- The approach to the HIV-infected patient with pulmonary disease is summarized by the algorithms in Figures 3 and 4. These are not intended to be followed in a rigid step-wise fashion. Rather, the practitioner s knowledge of the patient with his or her accompanying medical risks influences the path taken, including the
- HIV in children.
- Clin Chest Med. 1996 Dec;17(4):787-96. Unique Identifier : AIDSLINE MED/97168786
- Bye MR; Department of Pediatrics, Columbia University College of Physicians; and Surgeons, New York, New York, USA.
- Because children acquire HIV infection differently than adults, this article begins with a discussion of the epidemiology of AIDS in children. This is followed by a discussion of factors related to progression of the disease and survival in pediatric AIDS. A discussion of the pulmonary manifestations in children is fo
- HIV in illicit drug users.
- Clin Chest Med. 1996 Dec;17(4):797-807. Unique Identifier : AIDSLINE MED/97168787
- O'Donnell AE; Department of Medicine, Georgetown University Medical Center,; Washington, DC, USA.
- Illicit drug users comprise a substantial and growing proportion of the HIV-infected population. Although they develop pulmonary complications common to all HIV transmission groups, they also have unique respiratory illnesses due to the direct effect of the illicit drugs on the lung. Bacterial infections, tuberculosis
- Electrophoretic karyotype and in vitro antifungal susceptibility of Cryptococcus neoformans isolates from AIDS patients.
- Diagn Microbiol Infect Dis. 1995 Nov;23(3):99-103. Unique Identifier : AIDSLINE MED/97002253
- Barchiesi F; Hollis RJ; Messer SA; Scalise G; Rinaldi MG; Pfaller MA; Fungus Testing Laboratory, Department of Pathology, University of; Texas Health Science Center, San Antonio 78284-7750, USA.
- Electrophoretic karyotype (EK) was used to type 13 clinical isolates of Cryptococcus neoformans from eight AIDS patients. All of the isolates were also tested for their in vitro susceptibilities to fluconazole, itraconazole, D0870, flucytosine, and amphotericin B by a broth macrodilution technique performed according
- Laparoscopic sterilization in HIV-1-positive women.
- Contraception. 1996 Nov;54(5):305-7. Unique Identifier : AIDSLINE MED/97088127
- Intaraprasert S; Taneepanichskul S; Chaturachinda K; Department of Obstetrics and Gynaecology, Faculty of Medicine,; Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
- Laparoscopic sterilizations in HIV-1-positive women were performed. Patients, who were HIV-1-positive, underwent voluntary laparoscopic sterilization. The mean age of patients was 27.5 +/- 3.8 years. Most were of low socioeconomic status. The mean duration of the operation was 14.4 +/- 5.4 min. No accidental injury to
- Pulmonary technetium-99m diethylene triamine penta-acetic acid aerosol clearance as an index of lung injury.
- Eur J Nucl Med. 1997 Jan;24(1):81-7. Unique Identifier : AIDSLINE MED/97113154
- O'Doherty MJ; Peters AM; Department of Nuclear Medicine, St. Thomas' Hospital, Thomas' Trust,; London, UK.
- Although the clearance of an inhaled nebulised radioaerosol has long been employed as a measure of lung function, this test has not found favour in nuclear medicine units to the extent that might originally have been anticipated. In this review the theoretical basis of solute transfer is considered and the measurement
- Blockade of CD28/B7 co-stimulation by mCTLA4-Hgamma1 inhibits antigen-induced lung eosinophilia but not Th2 cell development or recruitment in the lung.
- Eur J Immunol. 1997 Jan;27(1):155-61. Unique Identifier : AIDSLINE MED/97174278
- Harris N; Campbell C; Le Gros G; Ronchese F; Malaghan Institute of Medical Research, Wellington School of Medicine,; New Zealand.
- We have studied the role of the CD28/B7 co-stimulatory pathway in the development of a Th2-type lung immune response. Mice injected two or three times intraperitoneally with ovalbumin in alum adjuvant and then re-exposed to the same antigen by intranasal i.n.) inoculation show infiltration of the lung tissue and appea
- Expression of pro-inflammatory cytokines by TCR alpha beta+ and TCR gamma delta+ T cells in an experimental model of colitis.
- Eur J Immunol. 1997 Jan;27(1):17-25. Unique Identifier : AIDSLINE MED/97174259
- Simpson SJ; Hollander GA; Mizoguchi E; Allen D; Bhan AK; Wang B; Terhorst C; Division of Immunology, Beth Israel Hospital, Boston, MA 02115, USA.
- An inflammatory bowel disease (IBD) comparable to human ulcerative colitis is induced upon transfer of T cell-depleted wild-type (F1) bone marrow into syngeneic T cell-deficient (tg epsilon26) mice (F1 > tg epsilon26). Previously we have shown that activated CD4+ T cells predominate in transplanted tg epsilon26 mice,
- Human Th1 cells preferentially induce interleukin (IL)-1beta while Th2 cells induce IL-1 receptor antagonist production upon cell/cell contact with monocytes.
- Eur J Immunol. 1997 Jan;27(1):171-7. Unique Identifier : AIDSLINE MED/97174280
- Chizzolini C; Chicheportiche R; Burger D; Dayer JM; Department of Internal Medicine, Hopital Cantonal Universitaire,; Geneva, Switzerland. chizzoli@epicure.hcuge.ch
- The role of human T cells in the induction and regulation, upon cell/cell contact, of inflammatory responses by monocytic cells was investigated. The production of interleukin (IL)-1beta and IL-1 receptor antagonist (IL-1Ra) by the monocytic THP-1 cell line was measured upon contact with either Th1 or Th2 cell clones.
- Bacille Calmette Guerin and interleukin-12 down-modulate interleukin-4-producing CD4+ NK1+ T lymphocytes.
- Eur J Immunol. 1997 Jan;27(1):183-8. Unique Identifier : AIDSLINE MED/97174282
- Emoto M; Emoto Y; Kaufmann SH; Department of Immunology, University of Ulm, Germany.
- Early production of interleukin-12 (IL-12) by macrophages and of IL-4 from CD4+ NK1+ T cells influence development of the acquired immune response against infectious agents, namely differentiation of interferon-gamma-secreting T helper 1 (Th1) cells against intracellular pathogens and of IL-4-producing Th2 cells again
- A novel peripheral CD4+ CD8+ T cell population: inheritance of CD8alpha expression on CD4+ T cells.
- Eur J Immunol. 1997 Jan;27(1):189-93. Unique Identifier : AIDSLINE MED/97174283
- Luhtala M; Lassila O; Toivanen P; Vainio O; Turku Immunology Center, Department of Medical Microbiology, Turku; University, Finland. marko.luhtala@utu.fi
- In this study we show the inheritance of a CD4+ CD8+ peripheral Tcell population in the H.B15 chicken strain. A large proportion of alphabeta T cells in peripheral blood (20-40%), spleen 10-20%) and intestinal epithelium (5-10%) coexpress CD4 and CD8alpha, but not CD8beta. CD4+ CD8alpha alpha cells are functionally no
- Co-receptor-independent signal transduction in a mismatched CD8+ major histocompatibility complex class II-specific allogeneic cytotoxic T lymphocyte.
- Eur J Immunol. 1997 Jan;27(1):55-61. Unique Identifier : AIDSLINE MED/97174264
- Eshima K; Tachibana M; Suzuki H; Yamazaki S; Shinohara N; Laboratory of Cellular Immunology, Mitsubishi Kasei Institute of Life; Sciences, Tokyo, Japan.
- The contribution of co-receptors in signal transduction upon T cell receptor (TCR)-mediated recognition of major histocompatibility complex (MHC) class II antigen by mature T lymphocytes expressing TCR derived from the apparently co-receptor-independent, I-Ak-specific allogeneic CD8+ CTL clone QM11 has been examined.
- Antigen presentation by interferon-gamma-treated thyroid follicular cells inhibits interleukin-2 (IL-2) and supports IL-4 production by B7-dependent human T cells.
- Eur J Immunol. 1997 Jan;27(1):62-71. Unique Identifier : AIDSLINE MED/97174265
- Lombardi G; Arnold K; Uren J; Marelli-Berg F; Hargreaves R; Imami N; Weetman A; Lechler R; Department of Immunology, Royal Postgraduate Medical School, London,; GB. glombard@rpms.ac.uk
- The consequence of recognition of antigen on antigen-presenting cells that are induced to express major histocompatibility complex (MHC) class II molecules following an inflammatory process is still not clear. In this study, we have investigated the outcome of antigen presentation by epithelial cells and we have used
- Epidemiology of human T-lymphotropic virus type II (HTLV-II) infection in Spain. HTLV Spanish Study Group.
- Eur J Epidemiol. 1996 Dec;12(6):625-9. Unique Identifier : AIDSLINE MED/97137286
- Soriano V; Vallejo A; Gutierrez M; Tuset C; Cilla G; Martinez-Zapico R; Dronda F; Caballero E; Calderon E; Aguilera A; Martin AM; Llibre J; del Romero J; Ortiz de Lejarazu R; Ulloa F; Eiros J; Gonzalez-Lahoz J; Centro de Investigaciones Clinicas, Instituto de Salud Carlos III,; Madrid, Spain.
- The human T-lymphotropic virus type II (HTLV-II) has recently been associated with the genesis of some subacute neurological syndromes and, rarely, with atypical T-lymphoid malignancies. The virus is endemic in some Amerindian and African tribes, and among intravenous drug users (IDUs) in North America and Europe. Giv
- Clonal CD8+ and CD52- T cells are induced in responding B cell lymphoma patients treated with Campath-1H (anti-CD52).
- Eur J Haematol. 1997 Jan;58(1):5-13. Unique Identifier : AIDSLINE MED/97172283
- Osterborg A; Werner A; Halapi E; Lundin J; Harmenberg U; Wigzell H; Mellstedt H; Department of Oncology (Radiumhemmet) and Immunological Research; Laboratory, Karolinska Hospital, Stockholm, Sweden.
- Five patients with non-Hodgkin s lymphoma (NHL) and 4 patients with chronic lymphocytic leukaemia (CLL) were treated with the CDR-grafted (rat x human) monoclonal antibody (mAb) Campath-1H anti-CD52). Tumour regression was noted preferentially in peripheral blood and in the bone ma
- Adherence to guidelines for the prevention of HIV-related respiratory diseases.
- Eur Respir J. 1996 Nov;9(11):2318-22. Unique Identifier : AIDSLINE MED/97102838
- Montaner JS; Phillips P; Zala C; Craib KJ; O'Shaughnessy MV; Schechter MT; British Columbia Centre for Excellence in HIV/AIDS, St Paul's; Hospital, University of British Columbia, Vancouver, Canada.
- In this study we characterized the pattern of use of preventive therapies for specific respiratory diseases within a cohort of homosexual men and assessed the impact of targeted feedback on the level of compliance with guidelines for these diseases. All human immunodeficiency virus seronegative (HIV-) (n=169) and acqu
- Cystine levels, cystine flux, and protein catabolism in cancer cachexia, HIV/SIV infection, and senescence.
- FASEB J. 1997 Jan;11(1):84-92. Unique Identifier : AIDSLINE MED/97186554
- Hack V; Schmid D; Breitkreutz R; Stahl-Henning C; Drings P; Kinscherf R; Taut F; Holm E; Droge W; Department of Immunochemistry, Deutsches Krebsforschungszentrum,; Heidelberg, Germany.
- Patients with skeletal muscle catabolism (cachexia) fail to conserve the skeletal muscle protein and release large amounts of nitrogen as urea. Previous studies suggest that the threshold for the conversion of amino acids into other forms of chemical energy and the concomitant production of urea are regulated by the p
- Prospective evaluation of biopsy number for the diagnosis of viral esophagitis in patients with HIV infection and esophageal ulcer.
- Gastrointest Endosc. 1996 Nov;44(5):587-93. Unique Identifier : AIDSLINE MED/97088229
- Wilcox CM; Straub RF; Schwartz DA; Department of Medicine (Division of Digestive Diseases), Emory; University School of Medicine, Atlanta, Georgia, USA.
- BACKGROUND: Establishing a diagnosis of viral esophagitis in patients with human immunodeficiency virus (HIV) infection has important clinical relevance. However, the number of biopsies required to diagnose viral esophagitis is currently unknown. METHODS: Over a 34-month period, all HIV-infected patients with esophage
- Disruption of the terminal base pairs of retroviral DNA during integration.
- Genes Dev. 1997 Feb 1;11(3):371-82. Unique Identifier : AIDSLINE MED/97182550
- Scottoline BP; Chow S; Ellison V; Brown PO; Department of Biochemistry, Stanford University Medical School,; California 94305-5428, USA.
- Integrase catalyzes two essential steps in the integration of the retroviral genome--end processing and strand transfer--both of which require the interaction of integrase with viral att sites located at the ends of viral genomic DNA. These two different polynucleotidyl transfer reactions are apparently carried out by
- Use of human recombinant growth hormone and human recombinant insulin-like growth factor-I in patients with human immunodeficiency virus infection.
- Horm Res. 1996;46(4-5):215-21. Unique Identifier : AIDSLINE MED/97107899
- Hirschfeld S; Pediatric Branch, National Cancer Institute, Bethesda, Md 20892, USA.
- Infection with the human immunodeficiency virus (HIV) can lead to global alterations in metabolism as well as immunodeficiency. There is dysregulation of endocrine function in adults and children, the extent and magnitude correlating with disease progression. Some of the more prominent abnormalities occur in the thyro
- Relative impact of HLA phenotype and CD4-CD8 ratios on the clinical expression of hemochromatosis.
- Hepatology. 1997 Feb;25(2):397-402. Unique Identifier : AIDSLINE MED/97174219
- Porto G; Vicente C; Teixeira MA; Martins O; Cabeda JM; Lacerda R; Goncalves C; Fraga J; Macedo G; Silva BM; Alves H; Justica B; de Sousa M; Department of Molecular Pathology and Immunology, Abel Salazar; Institute for the Biomedical Sciences, Porto, Portugal.
- Hemochromatosis is a hereditary iron-overload disease linked to HLA. The clinical expression of hemochromatosis is influenced by sex and age. However, other factors must account for the notorious heterogeneity of expression of the disease independent of sex, age, and HLA phenotype. The present study attempts to clarif
- Detection of type 2-like T-helper cells in hepatitis C virus infection: implications for hepatitis C virus chronicity.
- Hepatology. 1997 Feb;25(2):449-58. Unique Identifier : AIDSLINE MED/97174229
- Tsai SL; Liaw YF; Chen MH; Huang CY; Kuo GC; Liver Research Unit, Chang Gung Memorial Hospital, Taipei, Taiwan.
- One striking clinical feature of hepatitis C virus (HCV) infection is that more than 50% of patients with acute hepatitis C will develop chronic infection. To investigate its possible mechanisms, we examined the activation of type 2-like T-helper Th2-like) cells relating to the development of chronicity. Peripheral bl
- Hepatic drug delivery and gene therapy.
- Hepatology. 1997 Feb;25(2):484-91. Unique Identifier : AIDSLINE MED/97174234
- Zern MA; Kresina TF; Department of Medicine, Thomas Jefferson University, Philadelphia, PA; 19107, USA.
- On September 21-22, 1995, an international meeting entitled Targeting of Novel Therapeutics to the Liver and GI Tract was held at the Natcher Conference Center on the campus of the National Institutes of Health. The conference was sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases throu
- Pneumocystis carinii pneumonia in human immunodeficiency virus infected patients in Bombay: diagnosed by bronchoalveolar lavage cytology and transbronchial lung biopsy.
- Indian J Chest Dis Allied Sci. 1996 Oct-Dec;38(4):227-33. Unique Identifier : AIDSLINE MED/97171807
- Bijur S; Menon L; Iyer E; Deshpande J; Sivaraman A; Vaideeswar P; Mahashur AA; Department of Pathology, Seth G.S. Medical College and K.E.M.; Hospital, India.
- We report Pneumocystis carinii pneumonia (PCP) diagnosed by bronchoalveolar lavage cytology and transbronchial lung biopsy in three out of five human immunodeficiency virus (HIV) positive adult patients presenting with interstitial pneumonitis. One of these patients was serologically positive for HIV at the time of pr
- Pneumocystis carinii pneumonia simulating as pulmonary tuberculosis in AIDS.
- Indian J Chest Dis Allied Sci. 1996 Oct-Dec;38(4):253-7. Unique Identifier : AIDSLINE MED/97171811
- Arora VK; Tumbanatham A; Kumar SV; Ratnakar C; Department of Tuberculosis, Jawaharlal Institute of Postgraduate; Medical Education and Research, Pondicherry.
- Binding of 8-mer to 11-mer peptides carrying the anchor residues to slow assembling HLA class I molecules (HLA-B*5101).
- Immunogenetics. 1997;45(4):259-65. Unique Identifier : AIDSLINE MED/97155933
- Sakaguchi T; Ibe M; Miwa K; Kaneko Y; Yokota S; Tanaka K; Takiguchi M; Department of Tumor Biology, Institute of Medical Science, University; of Tokyo, Shirokanedai 4-6-1, Minato-ku, Tokyo 108, Japan.
- The binding of 303 8-mer to 11-mer peptides carrying the anchor residues at P2 and the C-terminus to HLA-B*5101 molecules was examined by a stabilization assay in which peptides were incubated with RMA-S-B*5101 cells at 26 degrees C for 3 h. Analysis of the binding of these peptides to HLA-B*5101 molecules showed that
- Alloantigen presentation to naive CD8+ T cells by mouse microglia: evidence for a distinct phenotype based on expression of surface-associated and soluble costimulatory molecules.
- Glia. 1996 Oct;18(2):118-28. Unique Identifier : AIDSLINE MED/97070849
- Askew D; Walker WS; Department of Immunology, St. Jude Children's Research Hospital,; Memphis, Tennessee 38105, USA.
- We previously showed that approximately one-third of mouse primary microglial clones derived from individual precursor cells residing in normal brain constitutively present alloantigens alloAgs) to naive CD8+ T cells (Moore et al.: J Neuroimmunol 41:203, 1992). To understand the basis for this alloAg presenting alloAg
- Respiratory cryptosporidiosis: case series and review of the literature.
- Infection. 1996 Sep-Oct;24(5):341-6. Unique Identifier : AIDSLINE MED/97081800
- Clavel A; Arnal AC; Sanchez EC; Cuesta J; Letona S; Amiguet JA; Castillo FJ; Varea M; Gomez-Lus R; Servicio de Microbiologia, Hospital Clinico Universitario, Zaragoza,; Spain.
- Five case of intestinal cryptosporidiosis with pulmonary involvement in patients with AIDS are reported. The diagnosis was based on the recognition of acid-fast oocysts in sputum or aspirated bronchial material and stool specimens. Coughing and excess secretions were present in all cases. Four patients had other assoc
- HIV-1 replication in the plasma and cerebrospinal fluid.
- Infection. 1996 Sep-Oct;24(5):367-71. Unique Identifier : AIDSLINE MED/97081804
- Lafeuillade A; Poggi C; Pellegrino P; Corti K; Profizi N; Sayada C; Unite Infectiologie, Hopital Chalucet, Toulon, France.
- The HIV-1 RNA in plasma and CSF samples from 40 HIV-1 infected patients was measured by a polymerase chain reaction (PCR) technique. The possible implication of cytokines in HIV-1 replication was investigated by measuring the concentrations of tumor necrosis factor alpha (TNF-alpha), macrophage colony stimulation fact
- Respiratory syncytial virus pneumonia in an AIDS patient.
- Infection. 1996 Sep-Oct;24(5):375-7. Unique Identifier : AIDSLINE MED/97081806
- van der Ven AJ; Swanink CM; van Crevel R; Bootsma GP; Koopmans PP; Galama JM; Dept. of Medical Microbiology, Academic Hospital Nijmegen, The; Netherlands.
- Pneumonia caused by respiratory syncytial virus in an AIDS patient is reported. A co-infection with cytomegalovirus was also demonstrated. Treatment with ribavirin and foscarnet produced good clinical response. The patient, known to have serious obstructive lung disease, suffered f
- Paradoxical worsening in tuberculosis during therapy in an HIV-infected patient [letter]
- Infection. 1996 Sep-Oct;24(5):390-1. Unique Identifier : AIDSLINE MED/97081809
- Mofredj A; Guerin JM; Leibinger F; Masmoudi R
- Oral administration of PSK can improve the impaired anti-tumor CD4+ T-cell response in gut-associated lymphoid tissue (GALT) of specific-pathogen-free mice.
- Int J Cancer. 1997 Jan 27;70(3):362-72. Unique Identifier : AIDSLINE MED/97185960
- Harada M; Matsunaga K; Oguchi Y; Iijima H; Tamada K; Abe K; Takenoyama M; Ito O; Kimura G; Nomoto K; Department of Virology, Kyushu University, Fukuoka, Japan.; harada@bioreg.kyushu-u.ac.jo
- We investigated both the effect and the mechanism of oral (p.o.) administration of PSK, a protein-bound polysaccharide derived from Basidiomycetes, on the anti-tumor T-cell response in gut-associated lymphoid tissue (GALT). The p.o. administration of PSK significantly suppressed the growth of colon 26 carcinoma C-26)
- Self-care activities of women infected with human immunodeficiency virus.
- Holist Nurs Pract. 1997 Jan;11(2):18-26. Unique Identifier : AIDSLINE MED/97188217
- Sowell RL; Moneyham L; Guillory J; Seals B; Cohen L; Demi A; Department of Administrative and Clinical Nursing, South Carolina,; Columbia, USA.
- The article describes a qualitative focus group study exploring the self-care activities undertaken by women testing positive for human immunodeficiency virus (HIV) to promote and maintain their health. The sample included 27 women who participated in one of four focus group sessions. Participants represented women fr
- Going home: African-American caregiving for adult children with human immunodeficiency virus disease.
- Holist Nurs Pract. 1997 Jan;11(2):27-35. Unique Identifier : AIDSLINE MED/97188218
- Boyle JS; Ferrell JA; Hodnicki DR; Muller RB; School of Nursing, Medical College of Georgia, Augusta, USA.
- The caregiving literature has focused on European-American caregivers who are providing care to spouses or parents with Alzheimer s disease. The article reports ethnographic research exploring aspects of caregiving by rural African-American mothers for adult children with human immunodeficiency virus (HIV) disease. Ei
- Attitudes, concerns, and fear of acquired immunodeficiency syndrome among registered nurses in the United States.
- Holist Nurs Pract. 1997 Jan;11(2):36-49. Unique Identifier : AIDSLINE MED/97188219
- Wang JF; School of Nursing, West Virginia University, Morgantown, USA.
- The article reports a study describing nurses attitudes, concerns, and fear of acquired immunodeficiency syndrome (AIDS). A convenience sample consisting of 376 nurses in a mid-Atlantic state was drawn. An 84-item questionnaire was used to collect the data. Seven factors were derived from the subjects responses usin
- Human immunodeficiency virus infection risk among female sex partners of intravenous drug users in southern Arizona.
- Holist Nurs Pract. 1997 Jan;11(2):9-17. Unique Identifier : AIDSLINE MED/97188216
- Erickson JR; College of Nursing, University of Arizona, Tucson, USA.
- Epidemiologic data suggest that women who are sexual partners of intravenous drug users (IVDUs) are at increasing risk for infection with human immunodeficiency virus (HIV). The article reports a study describing living conditions, sex risk behaviors, knowledge about acquired immunodeficiency syndrome (AIDS), and perc
- Community-wide HIV counselling and testing in central Massachusetts: who is retested and does their behavior change?
- J Community Health. 1996 Feb;21(1):11-22. Unique Identifier : AIDSLINE MED/97059259
- McCusker J; Willis G; McDonald M; Sereti SM; Lewis BF; Sullivan JL; Department of Clinical Epidemiology and Community Studies, St. Mary's; Hospital Centre, Montreal, Quebec, Canada.
- HIV counselling and testing was provided to 4267 individuals between September 1987 and June 1992 at a multi-site program, including community clinics, drug treatment programs, and a men s prison in central Massachusetts. Half of those tested reported the risk behaviors targeted by the programs: injection drug use 38.
- Evaluation of a HIV/AIDS education program for adolescents.
- J Community Health. 1996 Feb;21(1):23-35. Unique Identifier : AIDSLINE MED/97059260
- Morton M; Nelson L; Walsh C; Zimmerman S; Coe RM; Department of Community and Family Medicine, Saint Louis University; School of Medicine, Missouri, USA.
- The adolescent population has recently been recognized as one of the groups at risk for human immunodeficiency virus (HIV) infection. Statistics are beginning to document the extent of this trend. This study is aimed at determining adolescent sexual behaviors and the efficacy of a medical student-run acquired immune d
- Program characteristics of home-delivered meals programs for persons with HIV and AIDS.
- J Community Health. 1996 Feb;21(1):37-49. Unique Identifier : AIDSLINE MED/97059261
- Balsam A; Grant N; Rogers BL; Public Health and Human Services for Brookline, MA, USA.
- The nutritional status of persons with HIV and AIDS [PWAs] is constantly challenged throughout the progression of the illness. Home-delivered meals programs for PWAs are rapidly developing across the country to address this problem among the growing population of people with HIV infection and AIDS. This study examined
- EBV-associated Kikuchi's histiocytic necrotizing lymphadenitis with cutaneous manifestations.
- J Am Acad Dermatol. 1997 Feb;36(2 Pt 2):342-6. Unique Identifier : AIDSLINE MED/97191257
- Yen A; Fearneyhough P; Raimer SS; Hudnall SD; Department of dermatology, University of Texas Medical Branch,; Galveston 77555-0741, USA.
- The clinical and pathologic findings of Kikuchi s histiocytic necrotizing lymphadenitis may mimic those of malignant lymphoma. We describe a 6-year-old boy with generalized lymphadenopathy, spiking fever, chills, myalgias, malaise, and erythematous, crusted papules. Although cutaneous manifestations have been noted in
- Fatal Aspergillus pericarditis in acquired immunodeficiency syndrome [letter]
- Intensive Care Med. 1996 Aug;22(8):831-3. Unique Identifier : AIDSLINE MED/97034601
- Dalhoff K; Braun J; Gatermann S; Djonlagic H
- Respiratory distress syndrome and septic shock due to varicella in an HIV-infected adult [letter]
- Intensive Care Med. 1996 Aug;22(8):835-6. Unique Identifier : AIDSLINE MED/97034604
- Mofredj A; Guerin JM; Madec Y; Leibinger F
- Love, lust, and fear: safer sex decision making among gay men.
- J Homosex. 1995;30(1):53-73. Unique Identifier : AIDSLINE MED/97063731
- Ames LJ; Atchinson AB; Rose DT; State University of New York, Plattsburgh 12901, USA.
- In this, the second decade of the AIDS epidemic, most gay men have adequate knowledge of the most efficient transmission routes. Men know the techniques recommended to significantly reduce the likelihood of transmission. Men do not want to be infected. Yet some continue to take chances for sexual transmission of HIV.
- The discovery that an offspring is gay: parents', gay men's, and lesbians' perspectives.
- J Homosex. 1995;30(1):89-112. Unique Identifier : AIDSLINE MED/97063733
- Ben-Ari A; University of Haifa, Israel.
- This study explores and integrates parents , gay men s, and lesbians perceptions of the coming out process. The research employed a sample of thirty-two gay and lesbian young adults and twenty-seven parents. It investigated how family dynamics prior to the discovery of homosexuality could be related to post-discove
- Evaluation of the disinfectant effect of Solprogel against human immunodeficiency virus type 1 (HIV-1).
- J Hosp Infect. 1996 Nov;34(3):223-8. Unique Identifier : AIDSLINE MED/97082035
- Hernandez A; Belda FJ; Dominguez J; Matas L; Gimenez M; Caraballo M; Ramil C; Ausina V; Servicio de Microbiologia, Hospital Universitario Germans Trias i; Pujol, Universidad Autonoma de Barcelona, Spain.
- The antiviral activities of sodium dichloroisocyanurate (NaDCC) and a commercial product (Solprogel 2%) against human immunodeficiency virus type 1 (HIV-1) were investigated using a quantitative suspension test method. Solprogel is a compound that contains NaDCC and a biodegradable polymer of acrylic acid. Viral suspe
- Hospital-acquired infections in patients with HIV/AIDS [letter]
- J Hosp Infect. 1996 Dec;34(4):333-6. Unique Identifier : AIDSLINE MED/97126729
- Rogues AM; Dupon M; Morlat P; Lacoste D; Pellegrin JL; Ragnaud JM; Gachie JP
- CD4+ T cells kill CD8+ T cells via Fas/Fas ligand-mediated apoptosis.
- J Immunol. 1997 Feb 15;158(4):1503-6. Unique Identifier : AIDSLINE MED/97180865
- Piazza C; Gilardini Montani MS; Moretti S; Cundari E; Piccolella E; Department of Cellular and Developmental Biology, University La; Sapienza, National Research Council of Italy (CNR), Rome.
- To explore the possibility that CD4+ T cells, described to mediate the elimination of themselves or B lymphocytes, could also mediate the elimination of CD8+ T cells, we analyzed apoptotic phenomena in cocultures of CD4+ and CD8+ autologous T cell lines. The data show that CD8+ T cells were lysed by activated CD4+ hel
- MHC affinity, peptide liberation, T cell repertoire, and immunodominance all contribute to the paucity of MHC class I-restricted peptides recognized by antiviral CTL.
- J Immunol. 1997 Feb 15;158(4):1507-15. Unique Identifier : AIDSLINE MED/97180866
- Deng Y; Yewdell JW; Eisenlohr LC; Bennink JR; Laboratory of Viral Diseases, National Institute of Allergy and; Infectious Diseases, Bethesda, MD 20892, USA.
- MHC class I-restricted T cell responses to viral proteins focus on a limited set of peptides. To better understand this phenomenon, we examined all of the 26 nonameric peptides encoded by the influenza virus A/ Puerto Rico /8/34 (PR8) conforming to the canonical Kd binding motif.
- IFN-gamma-inducing factor (IGIF) is a costimulatory factor on the activation of Th1 but not Th2 cells and exerts its effect independently of IL-12.
- J Immunol. 1997 Feb 15;158(4):1541-50. Unique Identifier : AIDSLINE MED/97180870
- Kohno K; Kataoka J; Ohtsuki T; Suemoto Y; Okamoto I; Usui M; Ikeda M; Kurimoto M; Fujisaki Institute, Hayashibara Biochemical Laboratories, Inc.,; Okayama, Japan.
- We have previously reported the cloning of a novel cytokine, IFN-gamma-inducing factor (IGIF), which shared some biologic activities with IL-12. In this study, we analyzed the effects of murine IGIF on the activation of T cells, and compared the effects with those of IL-12. IGIF alone had no effect on the activation o
- Regulation of CD28 costimulation in human CD8+ T cells.
- J Immunol. 1997 Feb 15;158(4):1551-8. Unique Identifier : AIDSLINE MED/97180871
- Lloyd TE; Yang L; Tang DN; Bennett T; Schober W; Lewis DE; Department of Microbiology and Immunology, Baylor College of Medicine,; Houston, Texas 77030, USA.
- Optimal stimulation and prevention of anergy in T cells requires signaling through the CD28 molecule. During HIV disease progression, CD28 expression is lost, particularly on CD8+ T cells. Because alterations in cytokine production patterns occur during HIV infection, we determined whether CD8+ T cell phenotype or fun
- The mechanism of in vitro T helper cell type 1 to T helper cell type 2 switching in highly polarized Leishmania major-specific T cell populations.
- J Immunol. 1997 Feb 15;158(4):1559-64. Unique Identifier : AIDSLINE MED/97180872
- Mocci S; Coffman RL; DNAX Research Institute of Molecular and Cellular Biology, Palo Alto,; CA 94304, USA.
- We have previously demonstrated that highly polarized CD4+ Th1 cells isolated from Leishmania major-infected mice could be switched to a Th2-like phenotype when cultured for 1 wk in the presence of APC, L. major Ag, and IL-4, suggesting that the reversion of a differentiated Th response could occur at the population l
- Type 2 helper T cell-type cytokines and the development of infectious" tolerance in rat cardiac allograft recipients.
- J Immunol. 1997 Feb 15;158(4):1572-81. Unique Identifier : AIDSLINE MED/97180874
- Onodera K; Hancock WW; Graser E; Lehmann M; Sayegh MH; Strom TB; Volk HD; Kupiec-Weglinski JW; Harvard Medical School, Department of Surgery, Brigham and Women's; Hospital, Boston, MA 02115, USA.
- CD4-targeted therapy with a nondepleting RIB-5/2 mAb abrogates accelerated (
- T cell priming against vesicular stomatitis virus analyzed in situ: red pulp macrophages, but neither marginal metallophilic nor marginal zone macrophages, are required for priming CD4+ and CD8+ T cells.
- J Immunol. 1997 Feb 15;158(4):1749-55. Unique Identifier : AIDSLINE MED/97180894
- Ciavarra RP; Buhrer K; Van Rooijen N; Tedeschi B; Department of Microbiology and Immunology, Eastern Virginia Medical; School, Norfolk 23501, USA.
- Since extensive degradation may be required to present complex Ags, we addressed whether macrophages (M phi) might function as APC for anti-viral cell-mediated immune responses. To study this question, murine splenic M phi were depleted by i.p. administration of liposome-encapsulated dichloromethylene diphosphonate (C
- Human airway smooth muscle cells express and release RANTES in response to T helper 1 cytokines: regulation by T helper 2 cytokines and corticosteroids.
- J Immunol. 1997 Feb 15;158(4):1841-7. Unique Identifier : AIDSLINE MED/97180906
- John M; Hirst SJ; Jose PJ; Robichaud A; Berkman N; Witt C; Twort CH; Barnes PJ; Chung KF; Department of Thoracic Medicine, National Heart and Lung Institute,; London, United Kingdom.
- RANTES is a basic 8-kDa polypeptide of the C-C chemokine subfamily with strong chemotactic activity for eosinophils, lymphocytes, and monocytes. We determined the regulation of RANTES production by human airway smooth muscle cells in culture. While TNF-alpha, but not IFN-gamma, increased RANTES mRNA expression and pro
- Inflammatory cytokines induce endothelial cells to produce and release basic fibroblast growth factor and to promote Kaposi's sarcoma-like lesions in nude mice.
- J Immunol. 1997 Feb 15;158(4):1887-94. Unique Identifier : AIDSLINE MED/97180912
- Samaniego F; Markham PD; Gendelman R; Gallo RC; Ensoli B; Institute of Human Virology, University of Maryland Biotechnology; Institute, Baltimore 21201, USA.
- Inflammatory cytokines including TNF-alpha, IL-1beta, and IFN-gamma are increased in sera and lesions of Kaposi s sarcoma KS) patients. Previous data have indicated that the combination of these cytokines as found in conditioned media from activated T cells induces normal endothelial cells to acquire the features of K
- Characteristic T helper 2 T cell cytokine abnormalities in autoimmune lymphoproliferative syndrome, a syndrome marked by defective apoptosis and humoral autoimmunity.
- J Immunol. 1997 Feb 15;158(4):1912-8. Unique Identifier : AIDSLINE MED/97180915
- Fuss IJ; Strober W; Dale JK; Fritz S; Pearlstein GR; Puck JM; Lenardo MJ; Straus SE; Mucosal Immunity Section, National Institute of Allergy and Infectious; Diseases, Bethesda, MD 20892, USA.
- Autoimmune lymphoproliferative syndrome (ALPS) is marked by massive lymphadenopathy, hepatosplenomegaly, autoimmunity and the presence of increased numbers of circulating and tissue TCR-alpha beta, CD4- CD8- T cells. The underlying defect is that of decreased T cell and B cell apoptosis, due in most, but not all, case
- Human T cell responses induced by vaccination with Mycobacterium bovis bacillus Calmette-Guerin.
- J Immunol. 1997 Feb 15;158(4):1949-55. Unique Identifier : AIDSLINE MED/97180919
- Ravn P; Boesen H; Pedersen BK; Andersen P; Tuberculosis Research Unit, Statens Serum Institut, Copenhagen,; Denmark.
- Many aspects of the widely used bacillus Calmette-Guerin (BCG) vaccine against tuberculosis are still the subject of controversy. There is a huge variation in efficacy from one clinical trial to another and no relationship between vaccine-induced skin test conversion and subsequent protection. We have studied in vitro
- Effect of HIV infection on leprosy: a three-year survey in Bamako, Mali.
- Int J Lepr Other Mycobact Dis. 1996 Dec;64(4):383-91. Unique Identifier : AIDSLINE MED/97182056
- Lienhardt C; Kamate B; Jamet P; Tounkara A; Faye OC; Sow SO; Bobin P; Institut Marchoux, Bamako, Mali.
- From February 1992 until June 1994, all patients with histologically proven leprosy examined at the Leprology Unit of the Institut Marchoux in Bamako, Mali , were screened for HIV serology. In total, 740 leprosy patients have been tested; 553 known, previously treated leprosy cases an
- Short-term follow up of patients with multibacillary leprosy and HIV infection.
- Int J Lepr Other Mycobact Dis. 1996 Dec;64(4):392-5. Unique Identifier : AIDSLINE MED/97182057
- Jacob M; George S; Pulimood S; Nathan N; Department of Dermatology, Christian Medical College and Hospital,; Vellore, Tamil Nadu, South India.
- During a period of 9 years, four male patients with HIV and Hansen s disease were detected in Tamil Nadu, South India . The sequence as to which infection came first is not known. All had high-risk sexual behavior with commercial sex workers and a past history of genital ulcer diseas
- The efficiency of CD4 recruitment to ligand-engaged TCR controls the agonist/partial agonist properties of peptide-MHC molecule ligands.
- J Exp Med. 1997 Jan 20;185(2):219-29. Unique Identifier : AIDSLINE MED/97169064
- Madrenas J; Chau LA; Smith J; Bluestone JA; Germain RN; Department of Microbiology and Immunology, The University of Western; Ontario, London, Canada.
- One hypothesis seeking to explain the signaling and biological properties of T cell receptor for antigen (TCR) partial agonists and antagonists is the coreceptor density/kinetic model, which proposes that the pharmacologic behavior of a TCR ligand is largely determined by the relative rates of (a) dissociation ofligan
- Negative selection in the thymus includes semimature T cells.
- J Exp Med. 1997 Jan 20;185(2):263-71. Unique Identifier : AIDSLINE MED/97169068
- Kishimoto H; Sprent J; Department of Immunology, IMM4, The Scripps Research Institute, La; Jolla, California 92037, USA.
- The thymic medulla plays a key role in negative selection self-tolerance induction) and contains differentiated T cells en route to the extrathymic environment. However, being relatively mature, medullary T cells are thought to be beyond the stage of tolerance induction. This paradox is resolved by the finding that me
- HIV-1 induces cytotoxic T lymphocytes in the cervix of infected women.
- J Exp Med. 1997 Jan 20;185(2):293-303. Unique Identifier : AIDSLINE MED/97169071
- Musey L; Hu Y; Eckert L; Christensen M; Karchmer T; McElrath MJ; Department of Medicine, The University of Washington School of; Medicine, Seattle 98195, USA.
- Although T lymphocytes are present in the genital mucosa, their function in sexually transmitted diseases is unproven. To determine if cervical T cells mediate HIV-specific cytolysis, mononuclear cells in cytobrush specimens from HIV-1-infected women were stimulated in vitro with antigen. Resultant cell lines lysed au
- Asynchronous coreceptor downregulation after positive thymic selection: prolonged maintenance of the double positive state in CD8 lineage differentiation due to sustained biosynthesis of the CD4 coreceptor.
- J Exp Med. 1997 Jan 20;185(2):357-62. Unique Identifier : AIDSLINE MED/97169077
- Barthlott T; Kohler H; Eichmann K; Max-Planck-Institut fur Immunobiologie, Freiburg, Germany.
- In several experimental systems analyzing the generation of single positive (SP) thymocytes from double positive (DP) thymocytes, CD4 SP cells have been shown to appear before CD8 SP cells. This apparent temporal asymmetry in the maturation of CD4 SP and CD8 SP thymocytes could either be due to divergent molecular dif
- Correlation of MRI and neuropathology in AIDS.
- J Neurol Neurosurg Psychiatry. 1997 Jan;62(1):92-5. Unique Identifier : AIDSLINE MED/97163601
- Everall IP; Chong WK; Wilkinson ID; Paley MN; Chinn RJ; Hall-Craggs MA; Scaravilli F; Lantos PL; Luthert PJ; Harrison MJ; Department of Neuropathology, Institute of Psychiatry, London, UK.
- OBJECTIVE: To assess the correlation between findings on radiological and neuropathological examinations of the brain. METHODS: The formalin fixed brains of 19 patients who had died of AIDS were examined by MRI and neuropathology. RESULTS: The rate of identification of cerebral atrophy was similar radiologically and n
- Mitochondrial DNA levels in the brain of HIV-positive patients after zidovudine therapy.
- J Neurol. 1996 Sep;243(9):648-51. Unique Identifier : AIDSLINE MED/97047146
- Davison FD; Sweeney BJ; Scaravilli F; Department of Neuropathology, Institute of Neurology, London, UK.
- Previous studies have shown that the antiviral nucleoside analogue zidovudine ( AZT ) depletes levels of mitochondrial DNA mtDNA) in muscle of patients on long-term therapy. In this study we found that in a similar group of eight HIV-positive patients r
- Increased adhesion of CD4+ and CD14+ mononuclear cells to cultured multiple sclerosis brain endothelial cells [letter]
- J Neurol. 1996 Sep;243(9):666-7. Unique Identifier : AIDSLINE MED/97047152
- Dufour A; Corsini E; Giombini S; Nespolo A; Milanese C; Salmaggi A
- AIDS-related Pneumocystis carinii pneumonia in older patients [see comments]
- J Gen Intern Med. 1996 Oct;11(10):591-6. Unique Identifier : AIDSLINE MED/97101163
- Keitz SA; Bastian LA; Bennett CL; Oddone EZ; DeHovitz JA; Weinstein RA; Center for Health Services Research in Primary Care, Durham Veterans; Administration Medical Center, NC 27705, USA.
- MAIN RESULTS: Compared with younger patients, patients aged 50 years or older were less likely to have acquired HIV via intravenous drug use or homosexual contact (p = .0001). Older patients were more likely to have comorbid diseases (12% vs 4%; p = .0001), had more frequent neurologic findings on admission (19% vs 9%
- Predicting progression to AIDS. An evaluation of two approaches.
- J Gen Intern Med. 1996 Oct;11(10):622-4. Unique Identifier : AIDSLINE MED/97101167
- Rabeneck L; Hartigan PM; Huang IW; Souchek J; Wray NP; Department of Veterans Affairs Health Services Research and; Development (HSR&D) Field Program, West Haven, Conn., USA.
- This study evaluated the predictive validity of two clinical staging systems for HIV infection (the Rabeneck and Royce systems) using data obtained from the Department of Veterans Affairs Cooperative Study Number 298, a randomized clinical trial involving 335 symptomatic patients with CD4 counts of 200 to 500/mm3. The
- Aging in AIDS; AIDS and aging [editorial; comment]
- J Gen Intern Med. 1996 Oct;11(10):645-7. Unique Identifier : AIDSLINE MED/97101173
- Justice AC; Whalen C
- Incidence of three sexually transmitted diseases during a safer sex promotion program for HIV-infected women.
- J Gen Intern Med. 1996 Dec;11(12):750-2. Unique Identifier : AIDSLINE MED/97168829
- Kissinger P; Clark R; Dumestre J; Bessinger R; Department of Medicine, Louistana State University, New Orleans 70112,; USA.
- Promotion of safer sex practices typically includes education, skills building, and condom distribution. To evaluate the impact of such promotions and describe risk factors for sexually transmitted disease (STD), a retrospective review of 741 sexually active HIV-infected women was conducted. The cohort was African-Ame
- Rotavirus infection and diarrhea in healthy and HIV-infected children: a cohort study [published erratum appears in J Pediatr Gastroenterol Nutr 1997 Mar;24(3):367]
- J Pediatr Gastroenterol Nutr. 1996 Nov;23(4):492-6. Unique Identifier : AIDSLINE MED/97114446
- Fontana M; Zuin G; Mammino A; Tocalli L; Marchisio P; Principi N; Fourth Pediatric Department, University of Milan Medical School,; Italy.
- Humoral and cellular immunities elicited by HIV-1 vaccination.
- J Pharm Sci. 1996 Dec;85(12):1317-24. Unique Identifier : AIDSLINE MED/97120475
- Shiver JW; Davies ME; Perry HC; Freed DC; Liu MA; Department of Virus and Cell Biology, Merck Research Laboratories,; West Point, PA 19486, USA.
- Recently it has been shown that immunization with plasmid DNA encoding genes for viral or bacterial antigens can elicit both humoral and cellular immune responses in rodents and nonhuman primates. In this study, mice and nonhuman primates were vaccinated by intramuscular injection with plasmids that express either a s
- Development of a single-shot subunit vaccine for HIV-1. 2. Defining optimal autoboost characteristics to maximize the humoral immune response.
- J Pharm Sci. 1996 Dec;85(12):1346-9. Unique Identifier : AIDSLINE MED/97120480
- Cleland JL; Barron L; Berman PW; Daugherty A; Gregory T; Lim A; Vennari J; Wrin T; Powell MF; Department of Pharmaceutical Research, Genentech, Inc., South San; Francisco, CA 94080, USA.
- The design of a single-shot subunit vaccine for HIV-1 with polylactic-coglycolic acid (PLGA) sustained-release technology to effect an autoboost of antigen (MN gp120) at a given time after the primary immunization requires in-depth knowledge about the timing, the duration, and the need for coadjuvant in the autoboost.
- Development of a single-shot subunit vaccine for HIV-1. 3. Effect of adjuvant and immunization schedule on the duration of the humoral immune response to recombinant MN gp120.
- J Pharm Sci. 1996 Dec;85(12):1350-7. Unique Identifier : AIDSLINE MED/97120481
- Cleland JL; Barron L; Daugherty A; Eastman D; Kensil C; Lim A; Weissburg RP; Wrin T; Vennari J; Powell MF; Department of Pharmaceutical Research, Genentech, Inc., South San; Francisco, CA 94080, USA.
- HIV-1 prophylaxis may require sterilizing immunity (i.e., the prevention of infection), and this is likely to demand a vaccine that gives high, long-lasting antibody titers. Although it is known that vaccine adjuvants and immunization schedule affect the magnitude of the immune response, there are few reports on ant
- HIV-1 survival kinetics in peritoneal dialysis effluent.
- Kidney Int. 1996 Nov;50(5):1659-62. Unique Identifier : AIDSLINE MED/97071108
- Farzadegan H; Ford D; Malan M; Masters B; Scheel PJ Jr; Department of Medicine, Johns Hopkins University School of Medicine,; Baltimore, Maryland, USA.
- Viable and potentially infectious HIV-1 has been recovered from the peritoneal dialysis effluent (PDE) of patients with end-stage renal disease (ESRD) who are infected with the human immunodeficiency virus (HIV). No information had previously been available as to how long HIV-1 could survive in this environment, and n
- Idiopathic collapsing focal segmental glomerulosclerosis: a clinicopathologic study.
- Kidney Int. 1996 Nov;50(5):1734-46. Unique Identifier : AIDSLINE MED/97071119
- Valeri A; Barisoni L; Appel GB; Seigle R; D'Agati V; Department of Medicine, Columbia University, College of Physicians and; Surgeons, New York, New York, USA.
- A review of all native kidney biopsies at our center from 1974 to 1993 identified 43 cases of idiopathic focal segmental glomerulosclerosis (FSGS) with predominantly collapsing features and lacking evidence of HIV-1 infection or intravenous drug use. No case was identified before 1979 and the incidence of this entity
- HIV post-exposure prophylaxis: complex issues in health care worker management [editorial]
- J S C Med Assoc. 1996 Oct;92(10):437-40. Unique Identifier : AIDSLINE MED/97144999
- Ball RT Jr
- Developing culturally sensitive HIV/AIDS and substance abuse prevention curricula for Native American youth.
- J Sch Health. 1996 Nov;66(9):322-7. Unique Identifier : AIDSLINE MED/97118749
- Baldwin JA; Rolf JE; Johnson J; Bowers J; Benally C; Trotter RT; Dept. of Health, Physical Education, Exercise Science, and Nutrition,; Northern Arizona University, Flagstaff 86011, USA.
- In 1990, researchers and health care professionals joined with members of several southwestern Native American communities to form an HIV/AIDS and substance abuse prevention partnership. Culturally sensitive approaches to theory-based interventions were developed into highly replicable, structured, school-based and co
- [Report of the first 2 cases of HIV-1 group O infection in Spain]
- Med Clin (Barc). 1996 Oct 5;107(11):418-21. Unique Identifier : AIDSLINE MED/97097129
- Garcia-Lerma G; Gutierrez M; Mas A; Bravo R; Aguilera O; Soriano V; Servicio de Enfermedades Infecciosas, Instituto de Salud Carlos III,; Madrid.
- BACKGROUND: The wide genetic variability of HIV-1 isolates has allowed to classify them into several subtypes. Very high divergent strains have been isolated recently from West Africa patients with AIDS, and they have been called HIV-1 group O outlier ). PATIENTS AND METHODS: In April 1995 a couple of patients was ref
- [Treatment against human immunodeficiency virus in terms of the viral load: yes or no? (editorial)]
- Med Clin (Barc). 1996 Oct 19;107(13):498-9. Unique Identifier : AIDSLINE MED/97097153
- Soriano V; Leal M
- [Prevention of human immunodeficiency virus infection: condoms or abstinence? (letter; comment)]
- Med Clin (Barc). 1996 Oct 19;107(13):516-7. Unique Identifier : AIDSLINE MED/97097157
- Ruiz I; Latour J; Arranz M; Avino MJ
- Plasma trade and the HIV epidemic [letter]
- Lancet. 1997 Feb 1;349(9048):327-8. Unique Identifier : AIDSLINE MED/97176843
- Volkow P; Marin Lopez A; Torres I
- No news is good news at Washington AIDS meeting [news]
- Lancet. 1997 Feb 1;349(9048):331. Unique Identifier : AIDSLINE MED/97176848
- Schechter MT
- Rapid self testing for HIV infection.
- Lancet. 1997 Feb 1;349(9048):352-3. Unique Identifier : AIDSLINE MED/97176853
- Merson MH; Feldman EA; Bayer R; Stryker J; Department of Epidemiology and Public Health, Yale University School; of Medicine, New Haven, CT 06520-8034, USA.
- The Delta trial [letter; comment]
- Lancet. 1997 Feb 1;349(9048):358-9. Unique Identifier : AIDSLINE MED/97176863
- Zaretsky MD
- The Manchester seaman [letter; comment]
- Lancet. 1997 Feb 1;349(9048):360. Unique Identifier : AIDSLINE MED/97176865
- Stricker RB; Goldberg B
- HIV vaccines [letter; comment]
- Lancet. 1997 Feb 1;349(9048):361. Unique Identifier : AIDSLINE MED/97176867
- Ellenberg SS; Rida WN
- AIDS and professional secrecy in the United States.
- Med Sci Law. 1996 Jan;36(1):37-42. Unique Identifier : AIDSLINE MED/97063989
- Jayawardena H; Department of Forensic Medicine, Faculty of Medicine, University of; Kelaniya, Sri Lanka.
- OBJECTIVE: To create a legal awareness of AIDS patients right to privacy among the medical profession. DISCUSSION and RECOMMENDATIONS: Doctors should recognize confidentiality as a patient s right, since in most countries the AIDS patient is practically considered a person who is going through a punishment, having no
- Nonhuman primate spumavirus infections among persons with occupational exposure--United States, 1996.
- MMWR Morb Mortal Wkly Rep. 1997 Feb 14;46(6):129-31. Unique Identifier : AIDSLINE MED/97192246
- Nonhuman primate (NHP) species used in biomedical research may be infected with a variety of retroviruses including simian immunodeficiency virus (SIV), simian spumaviruses (i.e., simian foamy viruses [SPV]), simian T-lymphotrophic viruses (STLV), and/or simian type D retroviruses. All of these retroviruses cause life
- Cloning, characterization, and steroid-dependent posttranscriptional processing of RUSH-1 alpha and beta, two uteroglobin promoter-binding proteins.
- Mol Endocrinol. 1996 Nov;10(11):1335-49. Unique Identifier : AIDSLINE MED/97082217
- Hayward-Lester A; Hewetson A; Beale EG; Oefner PJ; Doris PA; Chilton BS; Department of Cell Biology & Biochemistry, Texas Tech University; Health Sciences Center, Lubbock 79430, USA.
- We previously used gel shift assays, Southwestern blots, and UV cross-linking to identify four proteins that bind to the 203-bp 5 -flanking region (-194/ +9) of the rabbit uteroglobin gene. Here we report cloning, by recognition site screening, the cDNAs for two of the uteroglobin promoter-binding proteins (95 kDa and
- AIDS 'cure' scientists go to top for funds [news]
- Nature. 1997 Feb 6;385(6616):474. Unique Identifier : AIDSLINE MED/97172259
- Cherry M
- HIV-1 tropism and co-receptor use [letter]
- Nature. 1997 Feb 6;385(6616):495-6. Unique Identifier : AIDSLINE MED/97172272
- Dittmar MT; McKnight A; Simmons G; Clapham PR; Weiss RA; Simmonds P
- Congress vows to contest 'unacceptable' NIH plans [news]
- Nature. 1997 Feb 13;385(6617):568. Unique Identifier : AIDSLINE MED/97177093
- Wadman M
- Canada calls in police to investigate data loss in HIV blood scandal [news]
- Nature. 1997 Feb 13;385(6617):572. Unique Identifier : AIDSLINE MED/97177096
- Canadian Red Cross seeks to reform itself [letter; comment]
- Nature. 1997 Feb 13;385(6617):574. Unique Identifier : AIDSLINE MED/97177097
- Giulivi A
- New impressions of Src and Hck [news; comment]
- Nature. 1997 Feb 13;385(6617):582-3, 585. Unique Identifier : AIDSLINE MED/97177101
- Pawson T
- Common mechanism of infection by lentiviruses [letter]
- Nature. 1997 Feb 13;385(6617):587. Unique Identifier : AIDSLINE MED/97177102
- Willett BJ; Hosie MJ; Neil JC; Turner JD; Hoxie JA
- CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia.
- Nature. 1997 Feb 13;385(6617):645-9. Unique Identifier : AIDSLINE MED/97177112
- He J; Chen Y; Farzan M; Choe H; Ohagen A; Gartner S; Busciglio J; Yang X; Hofmann W; Newman W; Mackay CR; Sodroski J; Gabuzda D; Division of Human Retrovirology, Dana-Farber Cancer Institute, Boston,; Massachusetts 02115, USA.
- Several members of the chemokine receptor family are used together with CD4 for HIV-1 entry into target cells. T cell line-tropic (T-tropic) HIV-1 viruses use the chemokine receptor CXCR4 as a co-receptor, whereas macrophage-tropic (M-tropic) primary viruses use CCR5 (refs 2-6). Individuals with defective CCR5 alleles
- Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement [see comments]
- Nature. 1997 Feb 13;385(6617):650-3. Unique Identifier : AIDSLINE MED/97177113
- Moarefi I; LaFevre-Bernt M; Sicheri F; Huse M; Lee CH; Kuriyan J; Miller WT; Laboratories of Molecular Biophysics, Howard Hughes Medical Institute,; The Rockefeller University, New York 10021, USA.
- The protein Hck is a member of the Src family of non-receptor tyrosine kinases which is preferentially expressed in haematopoietic cells of the myeloid and B-lymphoid lineages. Src kinases are inhibited by tyrosine-phosphorylation at a carboxy-terminal site. The SH2 domains of these enzymes play an essential role in t
- Contrast-enhancing progressive multifocal leukoencephalopathy: radiological and pathological correlations: case report.
- Neurosurgery. 1996 Nov;39(5):1031-4; discussion 1034-5. Unique Identifier : AIDSLINE MED/97061731
- Woo HH; Rezai AR; Knopp EA; Weiner HL; Miller DC; Kelly PJ; Department of Neurosurgery, New York University Medical Center, New; York, USA.
- OBJECTIVE AND IMPORTANCE: Progressive multifocal leukoencephalopathy (PML), a demyelinating disease caused by the JC papovavirus, is an opportunistic infection afflicting patients with impaired cellular immunity. Although initially described in patients with hematological malignancies, PML has become associated with s
- Thoracic spinal Pantopaque cyst and associated syrinx resulting in progressive spastic paraparesis: case report.
- Neurosurgery. 1996 Nov;39(5):1040-2. Unique Identifier : AIDSLINE MED/97061733
- Tabor EN; Batzdorf U; Division of Neurosurgery, University of California Los Angeles, School; of Medicine, USA.
- OBJECTIVE AND IMPORTANCE: We describe a unique presentation of a thoracic spinal Pantopaque cyst. Although Pantopaque is no longer used, sequelae of its long-term use may continue to surface. CLINICAL PRESENTATION: Our patient presented to the emergency room with 4 months of progressive lower extremity numbness, spast
- Radiotherapy in the treatment of symptomatic vertebral hemangiomas: technical case report.
- Neurosurgery. 1996 Nov;39(5):1054-8. Unique Identifier : AIDSLINE MED/97061737
- Bremnes RM; Hauge HN; Sagsveen R; Department of Oncology, University Hospital of Tromso, Norway.
- OBJECTIVE AND IMPORTANCE: In contrast to the frequent finding of vertebral hemangiomas at autopsy and during radiographical examinations, symptomatic lesions are rare. In the literature, a variety of therapies and combinations of therapies have been reported. There is, however, significant inconsistency regarding whic
- [Clinical significance of diplopia in HIV infection. Assessment of a personal caseload and review of the literature]
- Minerva Med. 1996 Nov;87(11):515-23. Unique Identifier : AIDSLINE MED/97170941
- Seminari E; Cocchi L; Antoniazzi E; Giacchino R; Maserati R; Istituto di Clinica delle Malattie Infettive, IRCCS Policlinico San; Matteo, Universita degli Studi, Pavia.
- Diplopia is one of the neuro-ophthalmic manifestations that can be observed during HIV-infection. The etiologic agents of diplopia in HIV-positive patients can be identified with HIV itself or opportunistic pathogens or other related conditions. We reviewed the clinical records of 13 HIV-positive patients with mono or
- [CD4 lymphocytopenia in patients without significant clinical pathology]
- Minerva Med. 1996 Nov;87(11):539-44. Unique Identifier : AIDSLINE MED/97170944
- Cascio G; Massobrio AM; Cascio B; Bosso E; Anania A; Dipartimento di Medicina Interna, Universita degli Studi, Torino.
- There are different causes of CD4 lymphocytopenia: neoplastic pathology, immunosuppressive therapy or other iatrogenic forms. In addition to these causes, an important role is certainly played by HIV infection which, at the AIDS stage, constantly accompanies progressive CD4 lymphocytopenia, with or without affecting t
- Liver disease in dialysis patients with antibodies to hepatitis C virus.
- Nephrol Dial Transplant. 1996 Nov;11(11):2265-8. Unique Identifier : AIDSLINE MED/97096660
- al-Wakeel J; Malik GH; al-Mohaya S; Mitwalli A; Baroudi F; el Gamal H; Kechrid M; Division of Nephrology, Security Forces Hospital, Riyadh, Saudi; Arabia.
- Eighty-three patients with chronic end-stage renal failure, including 65 on haemodialysis and 18 on intermittent peritoneal dialysis, were evaluated for hepatitis B virus profile and antibodies to hepatitis C virus (HCV). All those positive for HBsAg were excluded from the study. Nineteen patients were found to be pos
- Crescentic IgA nephropathy and acute renal failure in an HIV-positive patient with enteric salmonella infection.
- Nephrol Dial Transplant. 1996 Nov;11(11):2320-3. Unique Identifier : AIDSLINE MED/97096673
- Hsieh WS; Szukala S; Howell DN; Conlon PJ; Department of Medicine, Duke University Medical Center, Durham, NC; 27710, USA.
- Advances in assessment and management of HIV/AIDS-associated wasting syndrome [news]
- Nurse Pract. 1996 Feb;21(2):124, 126. Unique Identifier : AIDSLINE MED/97063920
- Grodesky MJ
- Group B streptococcus colonization in pregnant diabetic women.
- Obstet Gynecol. 1997 Feb;89(2):257-60. Unique Identifier : AIDSLINE MED/97167342
- Ramos E; Gaudier FL; Hearing LR; Del Valle GO; Jenkins S; Briones D; Department of Obstetrics and Gynecology, University of Florida Health; Science Center, Jacksonville, USA.
- OBJECTIVE: To evaluate the influence of maternal diabetes on the risk of group B streptococcus colonization during pregnancy. METHODS: We prospectively analyzed data on 105 pregnant women with diabetes mellitus, both pregestational and gestational, and a control group of 300 pregnant women without carbohydrate intoler
- Mobilizing communities to prevent HIV/AIDS: a nursing perspective.
- N J Nurse. 1996 Sep;26(7):8. Unique Identifier : AIDSLINE MED/97100682
- Vitiello-Taylor MA
- [The body's defense against intracellular bacteria]
- Nord Med. 1997 Jan;112(1):10-3. Unique Identifier : AIDSLINE MED/97162698
- Tarnvik A; Institutionen for infektionssjukdomar, Ume~a universitet.
- The separation of the two pathways of differentiation of CD4 T cells is fundamental to an understanding of host defence against intracellular bacteria. Th1 cells, but not Th2 cells, promote effective host response. Elucidation of the mechanisms responsible for the differentiation of Th1 and Th2 cells will facilitate t
- Mixed backbone antisense oligonucleotides: design, biochemical and biological properties of oligonucleotides containing 2'-5'-ribo- and 3'-5'-deoxyribonucleotide segments.
- Nucleic Acids Res. 1997 Jan 15;25(2):370-8. Unique Identifier : AIDSLINE MED/97169424
- Kandimalla ER; Manning A; Zhao Q; Shaw DR; Byrn RA; Sasisekharan V; Agrawal S; Hybridon Inc., One Innovation Drive, Worcester, MA 01605, USA.
- We have designed and synthesized mixed backbone oligonucleotides MBOs) containing 2 -5 -ribo- and 3 -5 -deoxyribonucleotide segments. Thermal melting studies of the phosphodiester MBOs three 2 -5 linkages at each end) with the complementary 3 -5 -DNA and -RNA target strands suggest that 2 -5 -ribonucleoside incorporat
- HTLV-I Tax self-association in optimal trans-activation function.
- Nucleic Acids Res. 1997 Jan 15;25(2):379-87. Unique Identifier : AIDSLINE MED/97169425
- Jin DY; Jeang KT; Molecular Virology Section, Laboratory of Molecular Microbiology,; National Institute of Allergy and Infectious Diseases, National; Institutes of Health, Bethesda, MD 20892-0460, USA.
- HTLV-I Tax protein is a potent transcriptional activator of viral and cellular genes. Tax does not bind DNA directly but interacts through protein-protein contact with host cell factors that recognize the viral long terminal repeat (LTR). Domains within Tax needed for protein-protein interaction have not been fully ch
- Pharmacokinetic evaluation of thiacetazone.
- Pharmacotherapy. 1996 Sep-Oct;16(5):735-41. Unique Identifier : AIDSLINE MED/97042870
- Peloquin CA; Nitta AT; Berning SE; Iseman MD; James GT; Department of Medicine, National Jewish Center for Immunology and; Respiratory Medicine, Denver, Colorado 80206, USA.
- STUDY OBJECTIVE: To investigate the steady-state pharmacokinetics of thiacetazone (TB-1), which is active in vitro against Mycobacterium avium complex (MAC). DESIGN: Open-label phase I study. SETTING: Specialized referral hospital. PATIENTS: Twelve healthy men and women. INTERVENTIONS: Oral TB-1 150 mg/day was adminis
- Pharmacokinetics and pharmacodynamics of subcutaneous interleukin-2 in HIV-infected patients.
- Pharmacotherapy. 1996 Sep-Oct;16(5):754-9. Unique Identifier : AIDSLINE MED/97042873
- Piscitelli SC; Wells MJ; Metcalf JA; Baseler M; Stevens R; Davey RT Jr; Department of Pharmacy, Warren G. Magnuson Clinical Center, National; Institute of Allergy and Infectious Diseases, National Institutes of; Health, Bethesda, Maryland 20892, USA. spisc@nih.gov
- STUDY OBJECTIVES: To assess the pharmacokinetics and pharmacodynamics of subcutaneously administered interleukin-2 IL-2 ) in patients infected with the human immunodeficiency virus HIV). DESIGN: Open, dose-escalating phase I clinical trial. SETTING: Government research
- [Tuberculosis. Current therapeutics]
- Presse Med. 1996 Dec 14;25(39):1909-15. Unique Identifier : AIDSLINE MED/97185930
- Tattevin P; Cremieux AC; Bouvet E; Carbon C; Service de Medecine interne, Hopital Bichat-Claude Bernard, Paris.
- Due to the constant decline in incidence up to the mid eighties, eradication of tuberculosis appeared to be an attainable objective in developed countries. Since then multiple factors HIV epidemic, poor social conditions in certain unfavored areas, population migrations, urbanization) have led to an increased frequenc
- [Treatment of cytomegalovirus infections in HIV infection]
- Presse Med. 1996 Dec 14;25(39):1967-73. Unique Identifier : AIDSLINE MED/97185939
- Breton G; Cremieux AC; Service de Medecine interne, Hopital Bichat-Claude Bernard, Paris.
- Cytomegalovirus ( CMV ) infections are common in patients with AIDS. Retinal localizations predominate, although digestive and neurological and more rarely pulmonary localizations are sometimes seen. Functional prognosis is poor in case of retinal infection requir
- Multicentric angiofollicular lymph node hyperplasia in children: a clinicopathologic study of eight patients.
- Mod Pathol. 1996 Dec;9(12):1135-42. Unique Identifier : AIDSLINE MED/97127721
- Smir BN; Greiner TC; Weisenburger DD; Department of Pathology and Microbiology, University of Nebraska; Medical Center, Omaha 68198-3135, USA.
- Multicentric angiofollicular lymph node hyperplasia (MAFH) is an idiopathic systemic disorder that has been reported only rarely in children. Therefore, we reviewed the clinical and pathologic features of eight patients listed in the Angiofollicular Lymph Node Hyperplasia Registry at our institution. The ages of the p
- Absence of Kaposi's sarcoma-associated herpesvirus-like DNA sequences in malignant vascular tumors of the serous membranes.
- Mod Pathol. 1996 Dec;9(12):1143-6. Unique Identifier : AIDSLINE MED/97127722
- Lin BT; Chen YY; Battifora H; Weiss LM; Division of Pathology, City of Hope National Medical Center, Duarte,; California 91010, USA.
- Reports connect Kaposi s sarcoma-associated herpesvirus (KSHV) with various types of Kaposi s sarcoma (KS) and body-cavity-based lymphomas (primary effusion lymphomas). KSHV DNA sequences have also been detected in a few non-KS malignant vascular tumors. To determine whether KSHV is associated with malignant vascular
- Activation of human B-MYB by cyclins.
- Proc Natl Acad Sci U S A. 1997 Jan 21;94(2):532-6. Unique Identifier : AIDSLINE MED/97165056
- Sala A; Kundu M; Casella I; Engelhard A; Calabretta B; Grasso L; Paggi MG; Giordano A; Watson RJ; Khalili K; Peschle C; Thomas Jefferson University, Kimmel Cancer Institute, Department of; Microbiology-Immunology, Philadelphia, PA, USA. A_Sala@lac.jci.tju.edu
- B-MYB expression is associated with cell proliferation and recent studies have suggested that it promotes the S phase of mammalian cells. Based on its homology to the transcription factors c-MYB and A-MYB, B-MYB is thought to be involved in transcriptional regulation; however, its activity is not detectable in several
- A Bcl-2 homolog encoded by Kaposi sarcoma-associated virus, human herpesvirus 8, inhibits apoptosis but does not heterodimerize with Bax or Bak.
- Proc Natl Acad Sci U S A. 1997 Jan 21;94(2):690-4. Unique Identifier : AIDSLINE MED/97165084
- Cheng EH; Nicholas J; Bellows DS; Hayward GS; Guo HG; Reitz MS; Hardwick JM; Department of Pharmacology and Molecular Sciences, Johns Hopkins; School of Medicine, Baltimore, MD 21205, USA.
- The Bcl-2 protein family is characterized by the ability to modulate cell death, and members of this family share two highly conserved domains called Bcl-2 homology 1 (BH1) and 2 (BH2) which have been shown to be critical for the death-repressor activity of Bcl-2 and Bcl-xL. Through sequence analysis we identified a n
- Inhibition of nuclear factor kappa B by prostaglandin A1: an effect associated with heat shock transcription factor activation.
- Proc Natl Acad Sci U S A. 1997 Jan 21;94(2):746-50. Unique Identifier : AIDSLINE MED/97165094
- Rossi A; Elia G; Santoro MG; Institute of Experimental Medicine, Consiglio Nazionale delle; Ricerche, Rome, Italy.
- Prostaglandins (PGs) function as intracellular signal mediators in the regulation of a variety of physiological and pathological processes, including inflammation and immune responses. Cyclopentenone PGs are characterized by antiviral activity against several viruses, including human immunodeficiency virus type 1 (HIV
- The effects of cocaine injections on mouse thymocyte population.
- Proc Soc Exp Biol Med. 1997 Feb;214(2):173-9. Unique Identifier : AIDSLINE MED/97186520
- Wu YB; Shen ML; Gu GG; Anderson KM; Ou DW; VA West Side Medical Center, Chicago, Illinois 60612, USA.
- C57 BL mice were injected daily with either saline or varied doses of cocaine (5-50 mg/kg), and thymocyte subpopulations were analyzed 4 hr after the fifth injection. Mice injected with either 25 or 50 mg/kg of cocaine showed a decrease in the percentage of CD4+8+ cells and increase of CD4-8-, CD4+, and CD8+ cells. Th
- Thoracic disease in children with AIDS.
- Radiographics. 1996 Nov;16(6):1349-62. Unique Identifier : AIDSLINE MED/97102022
- Marks MJ; Haney PJ; McDermott MP; White CS; Vennos AD; Department of Diagnostic Radiology, University of Maryland Medical; Center, Baltimore, USA.
- Knowledge of common and uncommon thoracic pathologic conditions in children with acquired immunodeficiency syndrome (AIDS) can expedite disease management. Chest radiography, computed tomography (CT), and magnetic resonance (MR) imaging are useful in cases involving possible complications of thoracic AIDS. Lymphocytic
- [Prevention of AIDS: experience with adolescents from a state elementary school in Porto Allegre]
- Rev Gaucha Enferm. 1995 Jan-Dec;16(1-2):52-7. Unique Identifier : AIDSLINE MED/97100850
- Dreher ML; Ferreira SR; Eidt OR
- This article refers to a participating experience in AIDS prevention with teenagers from 5th to 8th grade of a state elementary school, through workshops. This working method uses participating technics to allow relaxation, discussion and theme reflection by the group. The results obtained with this work of informatio
- Comparison of T-cell subpopulations in cats naturally infected with feline leukaemia virus or feline immunodeficiency virus.
- Res Vet Sci. 1996 Nov;61(3):222-6. Unique Identifier : AIDSLINE MED/97093289
- Hoffmann-Fezer G; Mortelbauer W; Hartmann K; Mysliwietz J; Thefeld S; Beer B; Thum I; Kraft W; GSF-Institut fur Immunologie, Munchen, Germany.
- T-cell subsets were studied by flow cytometry in 58 feline leukaemia virus (FeLV)-positive cats with naturally acquired FeLV infection to determine whether the changes in CD4+ or CD8+ T cell populations differed from those observed in 55 feline immunodeficiency virus (FIV)-positive cats with naturally acquired FIV inf
- Statistical Issues in HIV/AIDS Research. Proceedings of a symposium. Bethesda, Maryland, 12-13 June 1995.
- Stat Med. 1996 Nov 15-30;15(21-22):2269-490. Unique Identifier : AIDSLINE MED/97084866
- Use of observational data, including surveillance studies, for evaluating AIDS therapies.
- Stat Med. 1996 Nov 15-30;15(21-22):2273-88. Unique Identifier : AIDSLINE MED/97084867
- Gail MH; Division of Cancer Etiology, National Cancer Institute, Bethesda, MD; 20892-7368, USA.
- This article discusses some of the limitations of observational data for assessing therapeutic effects and categorizes observational studies according to the strength of evidence. Ecologic studies based on AIDS surveillance registries have demonstrated improvements over time in median survival following the onset of A
- Models for empirical Bayes estimators of longitudinal CD4 counts.
- Stat Med. 1996 Nov 15-30;15(21-22):2289-305; discussion 2337-40. Unique Identifier : AIDSLINE MED/97084868
- LaValley MP; DeGruttola V; Department of Epidemiology and Biostatistics, Boston University 02118,; USA.
- In this paper we consider the choice of model used in estimation of trajectories of CD4 T-cell counts by empirical Bayes estimators. Tsiatis et al. have demonstrated that empirical Bayes estimates of CD4 values correct for the bias resulting from measurement error when using CD4 as a covariate in a Cox model to predic
- Using multiple decrement models to estimate risk and morbidity from specific AIDS illnesses. Multicenter AIDS Cohort Study MACS).
- Stat Med. 1996 Nov 15-30;15(21-22):2307-21; discussion 2337-40. Unique Identifier : AIDSLINE MED/97084869
- Hoover DR; Peng Y; Saah AJ; Detels RR; Day RS; Phair JP; Department of Epidemiology, Johns Hopkins University School of Public; Health, Baltimore, Maryland, 21205, USA.
- A simple non-parametric approach is developed to simultaneously estimate net incidence and morbidity time from specific AIDS illnesses in populations at high risk for death from these illnesses and other causes. The disease-death process has four-stages that can be recast as two sandwiching three-state multiple decrem
- Parametric models to assess tracking of categorical high-risk sexual behaviour for HIV infection.
- Stat Med. 1996 Nov 15-30;15(21-22):2323-36; discussion 2337-40. Unique Identifier : AIDSLINE MED/97084870
- Gange SJ; Jacobson LP; Munoz A; Department of Epidemiology, Johns Hopkins School of Hygiene and Public; Health, Baltimore, MD 21205, USA.
- Prevalence and tracking (within-individual correlation) of high-risk behaviour measured in longitudinal studies provide a complementary description of how behaviour is maintained over time. Without tracking, when population prevalences are approximately constant over time, the steadiness of the aggregate pattern is li
- Sequential monitoring of clinical trials with multiple survival endpoints.
- Stat Med. 1996 Nov 15-30;15(21-22):2341-57; discussion 2367-70. Unique Identifier : AIDSLINE MED/97084871
- Williams PL; Department of Biostatistics, Harvard School of Public Health, Boston,; Massachusetts 02115, USA.
- Many clinical trials follow patients for several different types of survival endpoints, such as mortality, disease progression, and time until dose-limiting toxicity. Conduct of such trials often requires that the accumulating data be reviewed periodically to protect the safety of participating patients and possibly i
- Long-term follow-up in AIDS clinical trials.
- Stat Med. 1996 Nov 15-30;15(21-22):2359-66; discussion 2367-70. Unique Identifier : AIDSLINE MED/97084872
- Schoenfeld DA; Massachusetts General Hospital, Boston 02114, USA.
- There are several different strategies for the follow-up of patients on AIDS clinical trials. In some trials, data are only collected until patients stop protocol therapy for any reason. Alternatively, patients are followed until they have disease progression or the study ends. It has been suggested in some trials tha
- A control-conditional test for assessing HIV vaccine efficacy in small sample preclinical studies.
- Stat Med. 1996 Nov 15-30;15(21-22):2371-8; discussion 2405-12. Unique Identifier : AIDSLINE MED/97084873
- Albert JM; Biostatistics Research Branch, National Institute of Allergy and; Infectious Diseases, Bethesda, MD 20892, USA.
- In this paper, we discuss the analysis of data from small sample animal studies intended to evaluate HIV vaccine efficacy. The focus is on the chimpanzee model with HIV infection, a binary outcome, of primary interest. The problem becomes that of testing for a difference in independent binomial proportions, but aspect
- Comparing methods for calculating confidence intervals for vaccine efficacy.
- Stat Med. 1996 Nov 15-30;15(21-22):2379-92. Unique Identifier : AIDSLINE MED/97084874
- Ewell M; EMMES Corporation, Potomac, Maryland 20854, USA.
- A method is introduced for computing a Bayesian 95 per cent posterior probability region for vaccine efficacy. This method assumes independent vague gamma prior distributions for the incidence rates on each arm of the trial, and a Poisson likelihood for the counts of incident cases of infection. The approach is simila
- Assessing the effect of HIV vaccination on infectiousness.
- Stat Med. 1996 Nov 15-30;15(21-22):2393-404; discussion 2405-12. Unique Identifier : AIDSLINE MED/97084875
- Rida WN; Biostatistics Research Branch, National Institute of Allergy and; Infectious Diseases, Bethesda, MD 20892, USA.
- Traditionally, measures of vaccine efficacy have focused on a vaccine s ability to prevent infection or disease. HIV vaccination, however, may have important indirect effects by reducing the level of infectiousness of vaccinees who become infected. This latter effect is not captured by the usual estimators of vaccine
- Play the winner for phase II/III clinical trials.
- Stat Med. 1996 Nov 15-30;15(21-22):2413-23; discussion 2455-8. Unique Identifier : AIDSLINE MED/97084876
- Yao Q; Wei LJ; Department of Biostatistics, Harvard School of Public Health, Boston,; MA 02115, USA.
- In comparing two treatments under a typical sequential clinical trial setting, a 50-50 randomization design generates reliable data for making efficient inferences about the treatment difference for the benefit of patients in the general population. However, if the treatment difference is large and the endpoint of the
- HIV treatment strategies utilizing virologic and immunologic markers as criteria for changing treatments.
- Stat Med. 1996 Nov 15-30;15(21-22):2425-43; discussion 2455-8. Unique Identifier : AIDSLINE MED/97084877
- Elashoff M; Lagakos S; Food and Drug Administration, Gaithersburg, MD 20878, USA.
- Currently available antiviral drugs used in the treatment of AIDS patients are effective for a limited time. Therapy consisting of different drugs given in sequence thus has the potential to yield the greatest possible benefit to patients, yet it is not known in what order the drugs should be administered, or for how
- Data analysis issues for protocols with overlapping enrollment.
- Stat Med. 1996 Nov 15-30;15(21-22):2445-53; discussion 2455-8. Unique Identifier : AIDSLINE MED/97084878
- Larntz K; Neaton JD; Wentworth DN; Yurik T; School of Statistics, Terry Beirn Community Programs for Clinical; Research on AIDS (CPCRA), University of Minnesota, Minneapolis 55414,; USA.
- Many persons with HIV require and take several medications. The efficacy and safety of many of these medications are uncertain. Usually limited data on drug interactions are available. Thus simultaneous and sequential enrolment of patients into multiple studies is desired for reasons of science and efficiency. This pa
- Models for the incubation of AIDS and variations according to age and period.
- Stat Med. 1996 Nov 15-30;15(21-22):2459-73. Unique Identifier : AIDSLINE MED/97084879
- Munoz A; Xu J; Department of Epidemiology, Johns Hopkins School of Public Health,; Baltimore, MD 21205, USA.
- The objective of the methods proposed is to provide a parametric model for the incubation of AIDS and to use the chosen parameterization to test for the effect of age at seroconversion, and, after adjusting for markers of immunosuppression, to assess variations in periods corresponding to different levels of use of AI
- Non-parametric inference of a failure time distribution when the failure times are estimated.
- Stat Med. 1996 Nov 15-30;15(21-22):2475-90. Unique Identifier : AIDSLINE MED/97084880
- Kim HM; Lagakos SW; Department of Biostatistics, Harvard School of Public Health, Boston,; MA 02115, USA.
- We consider the estimation of a failure time distribution F when, instead of N i.i.d. realizations T1, T2, ..., TN from F, the observations consist of estimates of the Ti. If the Ti could be observed, a natural non-parametric estimator of F would be the Kaplan-Meier estimator. Thus, we examine the properties of the Ka
- [Liberation into the wild of wild felines--danger of the release of virus infections]
- Schweiz Arch Tierheilkd. 1996;138(12):579-85. Unique Identifier : AIDSLINE MED/97130960
- Lutz H; Hofmann-Lehmann R; Fehr D; Leutenegger C; Hartmann M; Ossent P; Grob M; Elgizoli M; Weilenmann P; Departement fur Innere Veterinarmedizin, Ethologie und Wildforschung,; Universitat Zurich.
- There are several felidae amongst the numerous endangered species. Means of aiding survival are the reintroduction to the wild of animals bred under the auspices of man and their relocation from densely populated to thinly populated areas. It is unlikely that the dangers of such reintroduction or relocation projects h
- Monitoring the spread of HIV and AIDS in Scotland 1983-1994.
- Scott Med J. 1996 Oct;41(5):131-8. Unique Identifier : AIDSLINE MED/97070001
- Goldberg D; Davis B; Allardice G; McMenamin J; Codere G; Scottish Centre for Infection and Environmental Health, Ruchill; Hospital, Glasgow.
- The transfusion immunomodulation theory: the Th1/Th2 paradigm and an analogy with pregnancy as a unifying mechanism.
- Semin Hematol. 1996 Oct;33(4):329-40. Unique Identifier : AIDSLINE MED/97073597
- Blumberg N; Heal JM; Department of Pathology and Laboratory Medicine, University of; Rochester, NY, USA.
- AIDS as a paradox of manhood and development in Kilimanjaro, Tanzania.
- Soc Sci Med. 1996 Oct;43(8):1169-78. Unique Identifier : AIDSLINE MED/97058907
- Setel P; National Centre for Epidemiology and Population Health/Health; Transition Centre, Australian National University, Canberra,; Australia.
- When AIDS emerged in Kilimanjaro region in 1984, many Chagga (the predominant ethnic group in the region) viewed it as a disease of development . Whereas AIDS was commonly seen in the West as a form of punishment for non-reproductive and non-productive lifestyles, in East Africa it represented paradoxes in reproducti
- Compulsory testing for HIV in Hungary.
- Soc Sci Med. 1996 Oct;43(8):1199-204. Unique Identifier : AIDSLINE MED/97058910
- Danziger R; Department of Public Health and Policy, London School of Hygiene and; Tropical Medicine, UK.
- Compulsory testing for the human immunodeficiency virus (HIV) has been a cornerstone of Hungary s AIDS prevention and care programme since 1988. This strategy is based on a two-fold public health rationale. Firstly, informing as many HIV positive people as possible of their serostatus is important for HIV prevention b
- [Evaluation of viral safety of a high-purity human factor VIII concentrate submitted to 2 specific virus inactivation treatments FANDHI) (see comments)]
- Sangre (Barc). 1996 Apr;41(2):131-6. Unique Identifier : AIDSLINE MED/96257015
- Ristol P; Gensana M; Fernandez J; Massot M; Biescas H; Darling A; Jorquera JI; Vericat F; Division de Investigacion y Desarrollo, Instituto Grifols, S.A.; Barcelona.
- AIM: To perform a validation study of the production process of a human high purity FVIII concentrate, obtained by affinity chromatography and treated with solvent-detergent and 80 degrees C, 72- hour dry heating in the final vial, in order to demonstrate its viral safety. MATERIAL AND METHODS: The ability to inactiva
- [Virus in hemophilia: current status and future perspectives]
- Sangre (Barc). 1996 Apr;41(2):141-5. Unique Identifier : AIDSLINE MED/96257017
- Aguilar C; Felix Lucia J; Servicio Regional de Hematologia y Hemoterapia, Hospital Miguel; Servet, Zaragoza.
- [Alcohol abuse in HIV infection]
- Ter Arkh. 1996;68(11):51-3. Unique Identifier : AIDSLINE MED/97147406
- Ruchkina EV; Beliaeva VV; Pokrovskii VV
- 249 cases of HIV infection (170 males, mean age 30.2 +/- 0.8 years; 79 females, mean age 28.7 +/- 0.9 years) have been analyzed for prevalence of alcoholization. 6 months after the establishment of HIV diagnosis the number of alcoholics in the studied group was greater than in this group before the diagnosis. 22% deve
- Immunomodulatory and protective effects of N-acetylcysteine in mitogen-activated murine splenocytes in vitro.
- Toxicology. 1997 Jan 15;116(1-3):219-26. Unique Identifier : AIDSLINE MED/97172440
- Omara FO; Blakley BR; Bernier J; Fournier M; Departement des Sciences Biologiques et TOXEN, Universite du Quebec a; Montreal, Canada.
- N-Acetylcysteine (NAC) is a pro-glutathione drug used to treat chronic lung disorders and because of its anti-AIDS virus activity in vitro, has been proposed for AIDS therapy. The effect of NAC on mitogen-activated-lymphocyte blastogenesis in C57B1/6 mouse splenocytes and ability of NAC to protect lymphocytes against
- Immunologic barriers to hepatic adenoviral gene therapy for transplantation.
- Transplantation. 1997 Jan 27;63(2):315-9. Unique Identifier : AIDSLINE MED/97172253
- DeMatteo RP; Chu G; Ahn M; Chang E; Burke C; Raper SE; Barker CF; Markmann JF; Harrison Department of Surgical Research and Institute for Human Gene; Therapy, University of Pennsylvania Medical Center, Philadelphia; 19104, USA.
- Adenoviral gene transfer has potential use to attenuate the immunogenicity of hepatic allografts. However, the clinical application of adenoviral gene therapy is currently impeded by the potent host immune response to the virus that limits the duration of its effects. In these studies, we identify the cellular and hum
- [Status on the HIV/AIDS epidemic in Denmark by the end of 1995]
- Ugeskr Laeger. 1997 Jan 27;159(5):585-90. Unique Identifier : AIDSLINE MED/97181917
- Smith E; Epidemiologisk afdeling, Statens Serum Institut, Kobenhavn.
- Data from the national Danish surveillance of HIV and AIDS were analysed in order to describe the epidemiological trends and to estimate the HIV incidence and the future AIDS-epidemic. An increasing number of AIDS cases were women and were heterosexually acquired. A stable number of new HIV-infections were identified
- Encephalitis associated with giant cells in a cat with naturally occurring feline immunodeficiency virus infection demonstrated by in situ hybridization.
- Vet Pathol. 1996 Nov;33(6):699-703. Unique Identifier : AIDSLINE MED/97109773
- Gunn-Moore DA; Pearson GR; Harbour DA; Whiting CV; Department of Veterinary Pathology, Faculty of Agriculture, University; of Tokyo, Japan.
- This report describes the clinical, pathological, immunocytochemical, and in situ hybridization characteristics of encephalitis associated with feline immunodeficiency virus (FIV) infection in a 4-year-old domestic cat. Lesions were identified throughout the brain, affecting the cerebrum, medulla, and cervical spinal
- Analysis of mutations within the cytoplasmic domain of the Moloney murine leukemia virus transmembrane protein.
- Virology. 1997 Jan 20;227(2):305-13. Unique Identifier : AIDSLINE MED/97170850
- Thomas A; Gray KD; Roth MJ; Department of Biochemistry, University of Medicine and Dentistry of; New Jersey, Robert Wood Johnson Medical School, Piscataway 08854, USA.
- The role of the cytoplasmic tail of the Moloney murine leukemia virus transmembrane protein in the regulation of syncytia was examined. Three mutations within the cytoplasmic tail were studied. Linker-insertion in7705-12a is within the viral-associated cytoplasmic tail, linker-insertion in7748-12a is within the R pept
- Inhibition of HIV-1 transcription and virus replication using soluble Tat peptide analogs.
- Virology. 1997 Jan 20;227(2):431-8. Unique Identifier : AIDSLINE MED/97170863
- Kashanchi F; Sadaie MR; Brady JN; Laboratory of Molecular Virology, National Cancer Institute, National; Institutes of Health, Bethesda, Maryland 20892, USA.
- The human immunodeficiency virus type 1 (HIV-1) transactivator Tat protein is essential for efficient viral gene expression and virus replication. The Tat core domain, a stretch of 12 amino acids between the cysteine-rich and the basic domain, is conserved in all HIV isolates and required for interaction with a number
- Intrathecal humoral immune response in HAM/TSP in relation to HLA haplotype analysis.
- Acta Neurol Scand. 1996 Oct;94(4):287-93. Unique Identifier : AIDSLINE MED/97091876
- Kitze B; Usuku K; Yashiki S; Ijichi S; Fujiyoshi T; Nakamura M; Izumo S; Osame M; Sonoda S; Center for Chronic Viral Diseases, Faculty of Medicine, Kagoshima; University, Japan.
- INTRODUCTION: In HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP), we correlated human leukocyte antigen HLA) haplotypes to the fine specificities of intrathecally synthesized IgG antibodies against HTLV-1. PATIENTS AND METHODS: HLA haplotypes of HAM/TSP patients were determined by the standard NIH
- Vascular changes in the cerebral cortex in HIV-1 infection. II. An immunohistochemical and lectinhistochemical investigation.
- Acta Neuropathol (Berl). 1996 Jul;92(1):35-41. Unique Identifier : AIDSLINE MED/96407036
- Buttner A; Mehraein P; Weis S; Institute of Neuropathology, Ludwig-Maximilians University, Munich,; Germany.
- In human immunodeficiency virus 1 (HIV-1)-infected patients, a hypoperfusion is seen by SPECT analyses in different brain regions but a specific pattern for the predominance of a specific brain region has not been found. The vessels of the cerebral cortex of the frontal, temporal, parietal, and occipital lobes of acqu
- Cellular proteases involved in the pathogenicity of human immunodeficiency and influenza viruses.
- Adv Exp Med Biol. 1996;389:233-40. Unique Identifier : AIDSLINE MED/97014181
- Kido H; Towatari T; Niwa Y; Okumura Y; Beppu Y; Division of Enzyme Chemistry, Institute of Enzyme Research, University; of Tokushima, Japan.
- HIV protease mutations leading to reduced inhibitor susceptibility.
- Adv Exp Med Biol. 1996;389:241-5. Unique Identifier : AIDSLINE MED/97014182
- Korant B; Lu Z; Strack P; Rizzo C; Molecular Biology Division, DuPont Merck Pharmaceutical Co, Glenolden,; Pennsylvania 19036, USA.
- Increase of tryptophan in serum and in cerebrospinal fluid of patients with HIV infection during zidovudine therapy.
- Adv Exp Med Biol. 1996;398:131-4. Unique Identifier : AIDSLINE MED/97062516
- Fuchs D; Gisslen M; Larsson M; Norkrans G; Hagberg L; Wachter H; Institute of Medical Chemistry and Biochemistry, University of; Innsbruck, Austria.
- A high percentage of patients with human immunodeficiency virus infection presents with decreased tryptophan concentrations in serum and cerebrospinal fluid. In parallel degradation products of tryptophan like kynurenine and quinolinic acid are increased. We investigated the behavior of tryptophan concentrations in 14
- Metabolism and biology of tryptophan. Some clinical implications.
- Adv Exp Med Biol. 1996;398:15-25. Unique Identifier : AIDSLINE MED/97062498
- Brown RR; Department of Human Oncology, University of Wisconsin Medical School,; Madison 53792, USA.
- Treatment and prevention of opportunistic infections in patients with human immunodeficiency virus infection.
- Adv Intern Med. 1996;41:31-84. Unique Identifier : AIDSLINE MED/97059265
- Walworth CM; Tavel JA; Kovacs JA; Laboratory of Immunoregulation, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Bethesda,; Maryland, USA.
- Imaging of pulmonary lymphomas.
- AJR Am J Roentgenol. 1997 Feb;168(2):339-45. Unique Identifier : AIDSLINE MED/97168609
- Lee KS; Kim Y; Primack SL; Department of Radiology, Samsung Medical Center, Seoul, South Korea.
- Central nervous system lymphoma not detectable on single-photon emission CT with thallium 201.
- AJNR Am J Neuroradiol. 1996 Oct;17(9):1687-90. Unique Identifier : AIDSLINE MED/97051988
- Fisher DC; Chason DP; Mathews D; Burns DK; Fleckenstein JL; Department of Radiology, University of Texas Southwestern Medical; Center, Dallas 75235, USA.
- A 33-year-old man with acquired immunodeficiency syndrome had an erosive supraglottic mass visible on CT scans of the neck; biopsy was postponed because of the patient s debilitated condition. Two weeks later, he was admitted with altered mental status; an MR image of the brain obtained at that time showed multiple bi
- Irradiated blood components [letter; comment]
- Am J Clin Pathol. 1997 Feb;107(2):252-3; discussion 253-4. Unique Identifier : AIDSLINE MED/97176540
- Mintz PD; Luban NL
- Irradiated blood components [letter; comment]
- Am J Clin Pathol. 1997 Feb;107(2):253; discussion 253-4. Unique Identifier : AIDSLINE MED/97176541
- Popovsky MA
- A heterologous substrate assay for the HIV-1 protease engineered in Escherichia coli.
- Anal Biochem. 1996 Nov 1;242(1):90-4. Unique Identifier : AIDSLINE MED/97082734
- Stebbins J; Deckman IC; Richardson SB; Debouck C; Department of Molecular Genetics, SmithKline Beecham Pharmaceuticals,; King of Prussia, Pennsylvania 19406, USA.
- A heterologous substrate assay for the human immunodeficiency virus type 1 (HIV-1) protease has been engineered in Escherichia coli. This assay detects the activity of the HIV-1 protease within intact bacterial cells and does not require biochemical purification of either the enzyme or the substrate. For this assay, n
- Sources of stigma associated with women with HIV.
- ANS Adv Nurs Sci. 1996 Dec;19(2):64-73. Unique Identifier : AIDSLINE MED/97093786
- Bunting SM; Memphis College of Nursing, University of Tennessee, Memphis, USA.
- In the United States many women infected with the human immunodeficiency virus (HIV) are poor women of African American or Hispanic American descent. Women with HIV have experienced many forms of oppression and discrimination and have been blamed as the victims of HIV and labeled as dr
- Reduced accumulation of drug in Candida krusei accounts for itraconazole resistance.
- Antimicrob Agents Chemother. 1996 Nov;40(11):2443-6. Unique Identifier : AIDSLINE MED/97070517
- Venkateswarlu K; Denning DW; Manning NJ; Kelly SL; Krebs Institute for Biomolecular Research, Department of Molecular; Biology and Biotechnology, University of Sheffield, United Kingdom.
- Due to intrinsic resistance Candida krusei is emerging as a systemic pathogen in AIDS patients undergoing fluconazole therapy, but acquired resistance to itraconazole has not been studied biochemically. We report here studies on the basis for azole resistance and sterol composition in C. krusei. An itraconazole-resist
- Inhibition of Trypanosoma cruzi growth in mammalian cells by purine and pyrimidine analogs.
- Antimicrob Agents Chemother. 1996 Nov;40(11):2455-8. Unique Identifier : AIDSLINE MED/97070520
- Nakajima-Shimada J; Hirota Y; Aoki T; Department of Parasitology, Juntendo University School of Medicine,; Tokyo, Japan.
- Trypanosoma cruzi, the causative agent of Chagas disease, exhibits two different developmental stages in mammals, the amastigote, an intracellular form that proliferates in the cytoplasm of host cells, and the trypomastigote, an extracellular form that circulates in the bloodstream. We have already established an in
- Spectrum of activity of levofloxacin against nontuberculous mycobacteria and its activity against the Mycobacterium avium complex in combination with ethambutol, rifampin, roxithromycin, amikacin, and clofazimine.
- Antimicrob Agents Chemother. 1996 Nov;40(11):2483-7. Unique Identifier : AIDSLINE MED/97070524
- Rastogi N; Goh KS; Bryskier A; Devallois A; Unite de la Tuberculose et des Mycobacteries, Institut Pasteur, Pointe; a Pitre, Guadeloupe, French West Indies.
- The spectrum of activity of levofloxacin was initially determined against 29 strains belonging to 16 species of atypical mycobacteria by measuring radiometric MICs. Levofloxacin MICs were 1 to 2 dilutions lower compared with those obtained for ofloxacin and 8 to 64 dilutions lower compared with those obtained for its
- Emergence of protease inhibitor resistance mutations in human immunodeficiency virus type 1 isolates from patients and rapid screening procedure for their detection.
- Antimicrob Agents Chemother. 1996 Nov;40(11):2535-41. Unique Identifier : AIDSLINE MED/97070533
- Vasudevachari MB; Zhang YM; Imamichi H; Imamichi T; Falloon J; Salzman NP; Laboratory of Molecular Retrovirology, SAIC Frederick, National Cancer; Institute-Frederick Cancer Research and Development Center, Maryland; 21702-1201, USA.
- Patient human immunodeficiency virus type 1 (HIV-1) isolates that are resistant to protease inhibitors may contain amino acid substitutions L10I/V, M46L/I, G-48V, L63P, V82A/F/T, I84V, and L90M in the protease gene. Substitutions at positions 82 and/or 90 occur in v
- 9-[2-(Phosphonomethoxy)propyl]adenine therapy of established simian immunodeficiency virus infection in infant rhesus macaques.
- Antimicrob Agents Chemother. 1996 Nov;40(11):2586-91. Unique Identifier : AIDSLINE MED/97070544
- Van Rompay KK; Cherrington JM; Marthas ML; Berardi CJ; Mulato AS; Spinner A; Tarara RP; Canfield DR; Telm S; Bischofberger N; Pedersen NC; California Regional Primate Research Center, University of California,; Davis 95616, USA. kkvanrompay@ucdavis.edu
- The long-term therapeutic and toxic effects of 9-[2-(phosphonomethoxy)propyl]adenine (PMPA) were evaluated in simian immunodeficiency virus (SIV)-infected newborn rhesus macaques. Four untreated SIV-infected newborn macaques developed persistently high levels of viremia, and three of the four animals had rapidly fatal
- Treatment of intracellular Mycobacterium avium complex infection by free and liposome-encapsulated sparfloxacin.
- Antimicrob Agents Chemother. 1996 Nov;40(11):2618-21. Unique Identifier : AIDSLINE MED/97070549
- Duzgunes N; Flasher D; Reddy MV; Luna-Herrera J; Gangadharam PR; Department of Microbiology, School of Dentistry, University of the; Pacific, San Francisco, California 94115, USA.
- Mycobacterium avium-M. intracellulare complex (MAC) is the most frequent cause of opportunistic bacterial infection in patients with AIDS. Previous studies have indicated that liposome-encapsulated aminoglycosides are highly effective in treating MAC infections in mice. We investigated whether the fluoroquinolone spar
- Quantitation of intracellular zidovudine phosphates by use of combined cartridge-radioimmunoassay methodology.
- Antimicrob Agents Chemother. 1996 Nov;40(11):2651-4. Unique Identifier : AIDSLINE MED/97070557
- Robbins BL; Waibel BH; Fridland A; Department of Infectious Disease, St. Jude Children's Research; Hospital, Memphis, Tennessee 38105, USA.
- This report describes the development of a potentially clinical method to measure the cellular metabolites of zidovudine (ZDV) in patients receiving the drug. This new method combines the use of Sep-Pak cartridges to separate ZDV phosphates with radioimmunoassaying to quantitate ZDV. The detection limit is 0.02 pmol/1
- Safety, tolerance, and efficacy of atevirdine in asymptomatic human immunodeficiency virus-infected individuals.
- Antimicrob Agents Chemother. 1996 Nov;40(11):2664-8. Unique Identifier : AIDSLINE MED/97070561
- Been-Tiktak AM; Williams I; Vrehen HM; Richens J; Aldam D; van Loon AM; Loveday C; Boucher CA; Ward P; Weller IV; Borleffs JC; Department of Internal Medicine, University Hospital Utrecht, The; Netherlands.
- Atevirdine is a nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1 (HIV-1). In this study we investigated the effect of atevirdine in asymptomatic antiretroviral naive HIV-infected patients with CD4+ cell counts of between 200 and 750 cells per mm3. Patients were randomized to receive
- Clinical and epidemiological aspects of diarrheal illness in pediatric AIDS patients in Sao Paulo, Brazil.
- Pediatr AIDS HIV Infect. 1995 Dec;6(6):335-9. Unique Identifier : AIDSLINE MED/97025298
- Negra MD; Queiroz W; Lian YC; Mangini AC; Dias AM; Palacci M; Tanaka H; Giudice MC; Instituto de Infectologia "Emilio Ribas", Sao Paulo, Brazil.
- Hemochrome parameters during the first two years of life in children with perinatal HIV-1 infection.
- Pediatr AIDS HIV Infect. 1995 Dec;6(6):340-5. Unique Identifier : AIDSLINE MED/97025299
- Galli L; de Martino M; Rossi ME; Panza B; Farina S; Vierucci A; Department of Pediatrics, University of Florence, Italy.
- Monthly hemochrome parameters were obtained during the first 2 years of age in 22 children with perinatal human immunodeficiency virus type-1 (HIV-1) infection and in 58 exposed seroreverted children. Timing and predictive value of hemochrome modifications were investigated. Exclusion criteria were hemoglobinopathies
- Retrospective study of children born to HIV-1-infected mothers in a pediatric hospital in Argentina.
- Pediatr AIDS HIV Infect. 1995 Dec;6(6):346-9. Unique Identifier : AIDSLINE MED/97025300
- Liberatore DI; Avila MM; Calarota S; Libonatti O; Pampuro S; Carrillo MG; Balbaryski J; Sala AM; Giraudi V; Massa B; et al; National Reference Center for AIDS, Department of Microbiology,; University of Buenos Aires School of Medicine, Argentina.
- The aim of this retrospective study, which included 103 children born to human immunodeficiency virus type 1 (HIV-1)- infected mothers, is to initiate a database on HIV-infected children, which has to date been unavailable in Argentina . All HIV-1 seropositive children admitted t
- Characteristics of children surviving to 5 years of age or older with vertically acquired HIV infection.
- Pediatr AIDS HIV Infect. 1995 Dec;6(6):350-3. Unique Identifier : AIDSLINE MED/97025301
- Kline MW; Paul ME; Bohannon B; Kozinetz CA; Shearer WT; Department of Pediatrics, Baylor College of Medicine and Texas; Children's Hospital, Houston, TX, USA.
- The objective of this study was to examine characteristics of long-term survivors (aged 5 years or older) of vertical human immunodeficiency virus (HIV) infection. A retrospective cohort study design was employed. Forty-eight (68%) of 71 children who were born before 1990 and evaluated in our center survived to at lea
- Peripartum seizure and HIV infection.
- Pediatr AIDS HIV Infect. 1995 Dec;6(6):354-5. Unique Identifier : AIDSLINE MED/97025302
- Finelli PF; Gonzalez JA; Department of Neurology, Hahnemann University, Philadelphia, PA, USA.
- Two patients with new-onset seizure within hours of parturition subsequently tested positive for human immunodeficiency virus HIV). The peripartum period appears to predispose asymptomatic HIV-infected individuals to seizure. Such patients, especially with suggestive risk factors, should be screened for HIV-antibody.
- ICD p24 antigen in HIV-infected children with low HIV-specific antibody.
- Pediatr AIDS HIV Infect. 1995 Dec;6(6):356-7. Unique Identifier : AIDSLINE MED/97025303
- Melvin AJ; Mohan K; Dragavon J; Division of Infectious Disease, Children's Hospital and Medical; Center, Seattle, WA, USA.
- Acute decrease in HIV-1 viral load after initiation of zidovudine therapy: implications for interrupting vertical transmission.
- Pediatr AIDS HIV Infect. 1995 Dec;6(6):358-9. Unique Identifier : AIDSLINE MED/97025304
- Jackson JB; Institute of Pathology and Department of Geographic Medicine, Case; Western Reserve University, University Hospitals of Cleveland, OH,; USA.
- Use of zidovudine ( AZT ) in pregnant women has recently been reported to reduce the rate of vertical transmission of human immunodeficiency virus type 1 (HIV-1) possibly through a reduction in maternal viral load. To determine how quickly AZT is able t
- AIDSphobia litigation.
- Pediatr AIDS HIV Infect. 1995 Dec;6(6):362-7. Unique Identifier : AIDSLINE MED/97025305
- Ginzburg HM; Department of Psychiatry and Neurology, Tulane University Medical; Center, New Orleans, Louisiana, USA.
- A significant proportion of adolescent girls engaging in risky behaviors will use confidential HIV counseling and testing services that are linked to primary care. Health-care providers play an important role in helping teens address their risk for and concerns about HIV infection by engaging adolescents in repeated d
- U.S. Public Health Service/Infectious Diseases Society of America USPHS/IDSA) guidelines for the prevention of opportunistic infections in persons infected with human immunodeficiency virus: a summary.
- Pediatr AIDS HIV Infect. 1995 Dec;6(6):372-96. Unique Identifier : AIDSLINE MED/97025306
- U.S. Public Health Service recommendations for human immunodeficiency virus counseling and voluntary testing for pregnant women.
- Pediatr AIDS HIV Infect. 1995 Dec;6(6):397-406. Unique Identifier : AIDSLINE MED/97025307
- These recommendations were developed by the U.S. Public Health Service to address the increasing epidemic of human immunodeficiency virus (HIV) infection among women and their infants. The recommendations stress the importance of early diagnosis of HIV infection for the health of both women and their infants and are b
- Update: HIV-2 infection among blood and plasma donors--United States, June 1992-June 1995.
- Pediatr AIDS HIV Infect. 1995 Dec;6(6):407-9. Unique Identifier : AIDSLINE MED/97025308
- Human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2) both cause acquired immunodeficiency syndrome (AIDS). Following the licensure of combination HIV-1/HIV-2 screening enzyme immunoassays (EIA), the Food and Drug Administration ( FDA ) recommended that beginning in June 1992 a
- In vivo depletion of NKR-P1 positive cells in the recipient prior to small bowel transplantation enhances graft-versus-host disease GvHD) in the rat.
- Transpl Int. 1996;9 Suppl 1:S275-80. Unique Identifier : AIDSLINE MED/97119022
- Fandrich F; Exner B; Papachrysanthou A; Zhu X; Jahnke T; Chambers WH; Zavazava N; Department of General and Thoracic Surgery, University of Kiel,; Germany.
- Recent evidence for major histocompatibility complex (MHC) class I antigen-directed recognition mechanisms of natural killer cells NKs) have revived interests in investigating non-adaptive immune responses in the framework of solid organ transplantation. A semi-allogeneic rat model of heterotopic small bowel transplan
- Changes in blood lymphocyte populations in experimental bowel allograft rejection.
- Transpl Int. 1996;9 Suppl 1:S281-5. Unique Identifier : AIDSLINE MED/97119023
- Navarro-Zorraquino M; Guemes A; Lozano R; Larrad L; Morandeira MJ; Salinas JC; Pastor C; Department of Surgery, University of Zaragoza, Spain.
- The aim of this study is to measure percentages of lymphocyte populations and IL-2R cellular expression in peripheral blood during the rejection of a small bowel allograft (SBA) in the rat. Thirty rats were allotted to three groups: A, control, no transplantation (Tx); B, rats receiving an orthotopic SBA; C, similar S
- Flow cytometric analysis of lymphocytes from rats following chronic ethanol treatment.
- Alcohol. 1996 Sep-Oct;13(5):467-71. Unique Identifier : AIDSLINE MED/97043872
- Helm RM; Wheeler G; Burks AW; Hakkak R; Badger TM; Department of Pediatrics, University of Arkansas for Medical Sciences,; Little Rock, USA.
- The current investigation focused on lymphoid cell populations of adult male Sprague-Dawley rats fed a total enteral nutrition diet in which ethanol provided 38% of the total calories. Rats received the National Research Council (NRC) recommended daily intake of nutrients 35 days. An evaluation of lymphocyte populatio
- HIV causes AIDS: Koch's postulates fulfilled [editorial]
- Curr Opin Immunol. 1996 Oct;8(5):613-8. Unique Identifier : AIDSLINE MED/97058056
- O'Brien SJ; Goedert JJ
- The Th1/Th2 paradigm and the allograft response.
- Curr Opin Immunol. 1996 Oct;8(5):688-93. Unique Identifier : AIDSLINE MED/97058066
- Strom TB; Roy-Chaudhury P; Manfro R; Zheng XX; Nickerson PW; Wood K; Bushell A; Department of Medicine, Harvard Medical School, Beth Israel Hospital,; Boston, MA 02115, USA. tstrom@bih.harvard.edu
- Although Th1- and Th2-type cytokine profiles have been associated with rejection and tolerance respectively, this paradigm may not be completely accurate. Instead, recent studies suggest that there could be a hierarchy of T-cell growth factors with regard to their ability to block tolerance and induce rejection (rathe
- Analysis of HIV-1 load in blood, semen and saliva: evidence for different viral compartments in a cross-sectional and longitudinal study.
- AIDS. 1996 Dec;10(14):F51-6. Unique Identifier : AIDSLINE MED/97125605
- Liuzzi G; Chirianni A; Clementi M; Bagnarelli P; Valenza A; Cataldo PT; Piazza M; Institute of Infectious Diseases, Universita Federico II Napoli,; Italy.
- OBJECTIVES: To quantify the HIV-1 load (measured as copies of viral RNA/ml using competitive reverse transcription-polymerase chain reaction) in blood, semen and saliva and to look for relationships between the viral burden, the clinical and immunological status and antiretroviral therapy. METHODS: Peripheral blood, s
- Lack of screening test sensitivity during HIV-1 non-subtype B seroconversions.
- AIDS. 1996 Dec;10(14):F57-60. Unique Identifier : AIDSLINE MED/97125606
- Apetrei C; Loussert-Ajaka I; Descamps D; Damond F; Saragosti S; Brun-Vezinet F; Simon F; Virology Laboratory, Bichat-Claude Bernard Hospital, Paris, France.
- OBJECTIVE: To evaluate the serological consequences of HIV-1 group M diversity we studied the ability of screening tests to detect anti-HIV antibodies in early seroconverters infected by different HIV subtypes. SETTING: Virology Department, Bichat-Claude Bernard Hospital, Paris, France
- Efficacy of triple combination therapy with zidovudine (ZDV) plus zalcitabine (ddC) plus lamivudine (3TC) versus double (ZDV+3TC) combination therapy in patients previously treated with ZDV+ddC.
- AIDS. 1996 Dec;10(14):F61-6. Unique Identifier : AIDSLINE MED/97125607
- Ruiz L; Romeu J; Martinez-Picado J; Schmit JC; Vandamme AM; Balague M; Cabrera C; Puig T; Tural C; Segura A; Sirera G; De Clercq E; Clotet B; Retrovirology Laboratory Institut de Recerca de la SIDA-Caixa, Spain.
- OBJECTIVE: To evaluate the immunological and virological efficacy of triple combination therapy with zidovudine (ZDV) plus zalcitabine ( ddC ) plus lamivudine (
- Acquisition of host cell-surface-derived molecules by HIV-1.
- AIDS. 1996 Dec;10(14):1611-20. Unique Identifier : AIDSLINE MED/97125608
- Frank I; Stoiber H; Godar S; Stockinger H; Steindl F; Katinger HW; Dierich MP; Institute for Hygiene and Ludwig Boltzmann Institute for AIDS; Research, Innsbruck, Austria.
- OBJECTIVE: To determine the acquisition of host cell-membrane-derived molecules by HIV-1 during the budding process, and to investigate whether the uptake of these molecules is cell-type-specific and selective. DESIGN: Virions, propagated by four different cell types were analysed for the presence of adhesion molecule
- Detection of CD8 T-cell expansions with restricted T-cell receptor V gene usage in infants vertically infected by HIV-1.
- AIDS. 1996 Dec;10(14):1621-6. Unique Identifier : AIDSLINE MED/97125609
- Halapi E; Gigliotti D; Hodara V; Scarlatti G; Tovo PA; DeMaria A; Wigzell H; Rossi P; Microbiology and Tumourbiology Centre, Karolinska Institute,; Stockholm, Sweden.
- OBJECTIVE: To investigate the T-cell receptor (TCR) repertoire usage in infants born to mothers infected with HIV-1 in order to discern possible perturbations in TCR usage as a consequence of HIV-1 infection. DESIGN: Blood samples from five HIV-1-infected and six non-infected children born to HIV-1-seropositive mother
- Filgrastim to treat neutropenia and support myelosuppressive medication dosing in HIV infection. G-CSF 92105 Study Group.
- AIDS. 1996 Dec;10(14):1627-33. Unique Identifier : AIDSLINE MED/97125610
- Hermans P; Rozenbaum W; Jou A; Castelli F; Borleffs J; Gray S; Ward N; Gori A; De Bona A; Ferre C; Lonca M; Lang JM; Ammassari A; Clumeck N; Department of Infectious Diseases, Saint-Pierre University Hospital,; Brussels, Belgium.
- BACKGROUND: Patients with HIV infection frequently experience disease or treatment-related myelosuppression leading to neutropenia. Neutropenia often leads to dose-reduction or discontinuation of important myelosuppressive therapy. OBJECTIVE: To examine the efficacy and safety of filgrastim for reversing neutropenia a
- Community-acquired bacteremia in HIV-positive patients: protective benefit of co-trimoxazole.
- AIDS. 1996 Dec;10(14):1635-9. Unique Identifier : AIDSLINE MED/97125611
- Edge MD; Rimland D; Veterans Affairs Medical Center, Decatur, GA 30033, USA.
- OBJECTIVE: To evaluate the effect of the type of Pneumocystis carinii pneumonia (PCP) prophylaxis on the development of community-acquired bacteremia. DESIGN: Case-control study using all cases of community-acquired bacteremia identified prospectively during a longitudinal study of all infections in a cohort of HIV-in
- Prevalence of anal human papillomavirus infection and anal cytologic abnormalities in HIV-seropositive women.
- AIDS. 1996 Dec;10(14):1641-7. Unique Identifier : AIDSLINE MED/97125612
- Hillemanns P; Ellerbrock TV; McPhillips S; Dole P; Alperstein S; Johnson D; Sun XW; Chiasson MA; Wright TC Jr; Department of Obstetrics and Gynecology, Klinikum Grosshadern,; Ludwig-Maximilians-University, Munich, Germany.
- OBJECTIVE: To determine the prevalence of anal human papillomavirus (HPV) infections and anal cytologic abnormalities in HIV-seropositive and HIV-seronegative women. DESIGN: This cross-sectional study of a cohort of women with known HIV serostatus involved a standardized interview and a gynecologic examination, includ
- HIV-2 infection in 12 European residents: virus characteristics and disease progression.
- AIDS. 1996 Dec;10(14):1649-55. Unique Identifier : AIDSLINE MED/97125613
- van der Ende ME; Schutten M; Ly TD; Gruters RA; Osterhaus AD; Department of Internal Medicine, University Hospital Dijkzigt,; Rotterdam, The Netherlands.
- OBJECTIVE: To assess the disease progression rate among 12 HIV-2-infected West European residents (nine of West African descent), compared with the disease progression rate among HIV-1-infected individuals of the same population, and the characteristics of the HIV-2 strains involved. METHODS: HIV-2-infected individual
- Oxandrolone in AIDS-wasting myopathy.
- AIDS. 1996 Dec;10(14):1657-62. Unique Identifier : AIDSLINE MED/97125614
- Berger JR; Pall L; Hall CD; Simpson DM; Berry PS; Dudley R; Department of Neurology, University of Miami School of Medicine,; Florida, USA.
- OBJECTIVE: To evaluate oxandrolone, an oral anabolic steroid with potent anabolic activity and minimal androgenic effects, for the treatment of AIDS-associated myopathy and wasting. METHODS: In a multicenter, double-blind study, 63 HIV-seropositive men with > 10% loss of body weight were randomized to receive either p
- The population biology of the interaction between HIV-1 and HIV-2: coexistence or competitive exclusion?
- AIDS. 1996 Dec;10(14):1663-73. Unique Identifier : AIDSLINE MED/97125615
- Anderson RM; May RM; Department of Zoology, University of Oxford, UK.
- BACKGROUND: The emergence and rapid world-wide spread of HIV provides an unusual opportunity for the study of the evolution and maintenance of virulence in a major human pathogen. OBJECTIVE: To analyse the available biological and epidemiological data on the pathogenicity, transmissibility and antigenic similarity of
- Vertical transmission of HIV-1: maternal immune status and obstetric factors. The European Collaborative Study.
- AIDS. 1996 Dec;10(14):1675-81. Unique Identifier : AIDSLINE MED/97125616
- Newell ML; Dunn DT; Peckham CS; Semprini AE; Pardi G; Department of Epidemiology, Institute of Child Health, London, UK.
- OBJECTIVE: To estimate the effect of maternal factors and events around the time of delivery on HIV-1 vertical transmission risk. DESIGN: Prospective study. SETTING: Twenty-two obstetric and paediatric clinics in seven European countries. PATIENTS OR OTHER PARTICIPANTS: Mothers identified as HIV-infected before or at
- The effect of HIV diagnosis on reproductive experience. Study Group for the Medical Research Council Collaborative Study of Women with HIV.
- AIDS. 1996 Dec;10(14):1683-7. Unique Identifier : AIDSLINE MED/97125617
- Stephenson JM; Griffioen A; Department of Sexually Transmitted Disease, University College London; Medical School, Mortimer Market Centre, UK.
- OBJECTIVES: To compare rates of reproductive events before and after HIV diagnosis in a cohort of women with HIV infection, and to consider the impact of HIV diagnosis on the outcome of pregnancy. DESIGN: Observational cohort study of 503 women recruited from 15 genitourinary medicine/HIV clinics in Britain and
- Demographic approaches to the estimation of incidence of HIV-1 infection among adults from age-specific prevalence data in stable endemic conditions.
- AIDS. 1996 Dec;10(14):1689-97. Unique Identifier : AIDSLINE MED/97125618
- Gregson S; Donnelly CA; Parker CG; Anderson RM; Wellcome Centre for the Epidemiology of Infectious Disease, Zoology; Department, Oxford University, UK.
- OBJECTIVE: To develop methods for estimating the incidence of HIV-1 infection among adults from age-specific prevalence data derived in stable endemic conditions. METHODS: Two methods are proposed. The first method is the Cumulative Incidence and Survival Method which treats HIV-1 prevalence at any given age as the cu
- Reliability and validity of an HIV-specific health-related quality-of-life measure for use with injecting drug users.
- AIDS. 1996 Dec;10(14):1699-705. Unique Identifier : AIDSLINE MED/97125619
- Carretero MD; Burgess AP; Soler P; Soler M; Catalan J; Psychological Medicine Unit, Chelsea and Westminster Hospital, London,; UK.
- OBJECTIVE: To assess the reliability and validity of an HIV-specific quality of life (QoL) questionnaire for use with injecting drug users (IDU). METHOD: One hundred IDU with HIV infection (27 asymptomatic, 48 symptomatic, 25 with AIDS) completed the HIV adaptation of the Medical Outcomes Study questionnaire (MOS-HIV)
- The acceptability of voluntary HIV antibody testing in the United States: a decade of lessons learned.
- AIDS. 1996 Dec;10(14):1707-17. Unique Identifier : AIDSLINE MED/97125620
- Irwin KL; Valdiserri RO; Holmberg SD; Centers for Disease Control and Prevention, Atlanta, Georgia 30333,; USA.
- OBJECTIVE: As the benefits of early diagnosis of HIV increase, US adults are more likely to be offered HIV counseling and testing in settings where they may not seek testing. Rates and determinants of counseling and testing acceptance in these settings are poorly understood. DESIGN: We reviewed articles and abstracts
- Changes in HIV risk behavior among injecting drug users: the impact of 21 versus 90 days of methadone detoxification.
- AIDS. 1996 Dec;10(14):1719-28. Unique Identifier : AIDSLINE MED/97125621
- Iguchi MY; Bux DA Jr; Lidz V; French JF; Baxter RC; Platt JJ; Department of Psychiatry, MCP-Hahnemann School of Medicine, Allegheny; University of the Health Sciences, Philadelphia, Pennsylvania; 19102-1192, USA.
- OBJECTIVE: To evaluate the hypothesis that long-term methadone detoxification would produce greater HIV risk reduction among injecting drug users (IDU) than short-term detoxification. DESIGN: Random assignment to 21 or 90 days of free detoxification. SETTING: Storefront offices in two cities, with referrals to outpati
- Needle exchange use among a cohort of injecting drug users.
- AIDS. 1996 Dec;10(14):1729-34. Unique Identifier : AIDSLINE MED/97125622
- Schoenbaum EE; Hartel DM; Gourevitch MN; Department of Epidemiology, Montefiore Medical Center, Albert Einstein; College of Medicine, Bronx, New York, USA.
- OBJECTIVE: To study prospectively injection behavior of injecting drug users (IDU) who did and did not utilize a local needle exchange in the Bronx, New York City. DESIGN: Since 1985, IDU attending a methadone maintenance program have been enrolled in a prospective study of HIV-related risk behaviors. Since 1989, when
- HIV-1 RNA quantification by one-tube quantitative NASBA in HIV-infected patients [letter]
- AIDS. 1996 Dec;10(14):1735-7. Unique Identifier : AIDSLINE MED/97125623
- Bettini P; Boeri E; Lillo F; Abecasis C; Farma E; Crociati E; Uberti-Foppa C; Varnier OE
- AIDS in a long-term HIV-1-infected patient with a stable high CD4+ cell count and conserved CD4+CD45RO+ subpopulation [letter]
- AIDS. 1996 Dec;10(14):1737-8. Unique Identifier : AIDSLINE MED/97125624
- Negri C; Rusconi S; Gori A; Riva C; Balotta C; Galli M
- Alternative tRNA primers for HIV [letter]
- AIDS. 1996 Dec;10(14):1738-40. Unique Identifier : AIDSLINE MED/97125625
- Lauermann V; Peden K; Boeke JD
- Long-term zidovudine responders: is there still rationale for HIV monotherapy? [letter]
- AIDS. 1996 Dec;10(14):1741. Unique Identifier : AIDSLINE MED/97125626
- Soriano V; Mas A; Heredia A; Vallejo A; Hewlett I; Epstein J; Gonzalez-Lahoz J
- Efficacy of a combined zidovudine plus didanosine therapy in one case of HIV-related thrombocytopenia non-responder to zidovudine alone or to anti-Rho immunoglobulin administration [letter]
- AIDS. 1996 Dec;10(14):1741-2. Unique Identifier : AIDSLINE MED/97125627
- Pizzigallo E; Sisto A; Iezzi A
- Evidence of activity of vinorelbine in patients with previously treated AIDS-associated Kaposi's sarcoma [letter]
- AIDS. 1996 Dec;10(14):1742-3. Unique Identifier : AIDSLINE MED/97125628
- Errante D; Fasan M; Rizzardini G; Landonio G; Pagani L; Zeroli C; Tirelli U
- Gout secondary to ritonavir and didanosine [letter]
- AIDS. 1996 Dec;10(14):1744. Unique Identifier : AIDSLINE MED/97125629
- Mehlhaff DL; Stein DS
- Lack of evidence for viral clearance in children born to HIV-infected mothers [letter]
- AIDS. 1996 Dec;10(14):1744-5. Unique Identifier : AIDSLINE MED/97125630
- Bravo R; Gutierrez M; Soriano V; Mellado MJ; Perez-Labad ML; Mas A; Gonzalez-Lahoz J; Martin-Fontelas P
- Orally administered amphotericin B in the treatment of oral candidiasis in HIV-infected patients caused by azole-resistant Candida albicans [letter]
- AIDS. 1996 Dec;10(14):1745-7. Unique Identifier : AIDSLINE MED/97125631
- Nguyen MT; Weiss PJ; LaBarre RC; Miller LK; Oldfield EC; Wallace MR
- Clinical characterization of thrombotic microangiopathy in HIV infection [letter]
- AIDS. 1996 Dec;10(14):1747-9. Unique Identifier : AIDSLINE MED/97125632
- Kado DM; Korotzer BS; Brass EP
- Steady sexual relationship with an HIV-positive partner and the progression rate to AIDS [letter]
- AIDS. 1996 Dec;10(14):1749-51. Unique Identifier : AIDSLINE MED/97125633
- Flateby G; Eskild A; Brekke T; Moi H
- Tumor necrosis factor alpha-mediated host defense against Pneumocystis carinii.
- Am J Respir Cell Mol Biol. 1997 Feb;16(2):110-1. Unique Identifier : AIDSLINE MED/97184314
- Limper AH; Department of Pulmonary and Critical Care and Internal Medicine, Mayo; Clinic and Foundation, Rochester, Minnesota 55905, USA.; limper.andrew@mayo.edu
- Exacerbation of murine Pneumocystis carinii infection by adenoviral-mediated gene transfer of a TNF inhibitor.
- Am J Respir Cell Mol Biol. 1997 Feb;16(2):112-8. Unique Identifier : AIDSLINE MED/97184315
- Kolls JK; Lei D; Vazquez C; Odom G; Summer WR; Nelson S; Shellito J; Division of Pediatric Pulmonology, LSU School of Medicine, New; Orleans, Louisiana 70112, USA.
- The role of mononuclear phagocytes and their cytokine products in host defense against Pneumocystis carinii (PC) remains unclear. The cytokine tumor necrosis factor (TNF) has been proposed as critical for host defense against this pathogen. To investigate the role of this cytokine in PC infection, we treated immunocom
- Pulmonary lymphoid cell activation and cytokine expression in murine AIDS-associated interstitial pneumonitis.
- Am J Respir Cell Mol Biol. 1997 Feb;16(2):153-61. Unique Identifier : AIDSLINE MED/97184320
- Cohen DA; Fitzpatrick EA; Hartsfield C; Gillespie MN; Avdiushko M; Kaplan AM; Department of Microbiology and Immunology, College of Medicine,; University of Kentucky Medical Center, Lexington 40536-0084, USA.
- Limited information is available about the pathogenesis of acquired immune deficiency syndrome (AIDS)-associated idiopathic interstitial pneumonitis, a common noninfectious complication of human immunodeficiency virus (HIV) infection. Infection of C57B1/6 mice with LP-BM5 retrovirus, a murine model of AIDS, leads to d
- Th1/Th2 cell distribution in pulmonary sarcoidosis.
- Am J Respir Cell Mol Biol. 1997 Feb;16(2):171-7. Unique Identifier : AIDSLINE MED/97184322
- Baumer I; Zissel G; Schlaak M; Muller-Quernheim J; Medical Hospital, Research Centre Borstel, Germany.
- Cytokines released by T lymphocytes activated in the course of sarcoidosis, e.g., interleukin-2 ( IL-2 ) and interferon-gamma IFN-gamma), indicate the presence of Th1 cells leading to the question of Th1/Th0/Th2 balance in sarcoidosis. The aim of this study was to evalua
- Structural requirements for and consequences of an antiviral porphyrin binding to the V3 loop of the human immunodeficiency virus (HIV-1) envelope glycoprotein gp120.
- J Mol Recognit. 1995 Nov-Dec;8(6):345-57. Unique Identifier : AIDSLINE MED/97076944
- Neurath AR; Strick N; Debnath AK; Laboratory of Biochemical Virology, The Lindsley F. Kimball Research; Institute of the New York Blood Center 10021, USA.
- Several porphyrin derivatives were reported to have anti-HIV-1 activity. Among them, meso-teta(4-carboxyphenyl)porphine (MTCPP) and other carboxyphenyl derivatives were the most potent inhibitors (EC50
- Intra-epithelial and invasive cervical neoplasia during HIV infection.
- Eur J Cancer. 1996 Dec;32A(13):2212-7. Unique Identifier : AIDSLINE MED/97190642
- Boccalon M; Tirelli U; Sopracordevole F; Vaccher E; Division of Medical Oncology and AIDS, Centro di Riferimento; Oncologico, Aviano (PN), Italy.
- Patients affected by human immunodeficiency virus (HIV) infection present an elevated risk of developing cancer. In the last 10 years, the relationship between human papilloma virus (HPV) infection and female cervical intra-epithelial neoplasia (CIN) has been established. Several studies have described an increased pr
- Malassezia yeast density in HIV-positive individuals [letter; comment]
- Br J Dermatol. 1997 Jan;136(1):138-9. Unique Identifier : AIDSLINE MED/97191361
- Pechere M; Saurat JH
- Bacillary angiomatosis: presentation of six patients, some with unusual features.
- Br J Dermatol. 1997 Jan;136(1):60-5. Unique Identifier : AIDSLINE MED/97191338
- Schwartz RA; Nychay SG; Janniger CK; Lambert WC; UMD--New Jersey Medical School, Newark, New Jersey 07103-2714, USA.
- Bacillary angiomatosis (BA) is an unusual systemic vascular proliferation seen predominantly in patients with the acquired immunodeficiency syndrome. These vascular lesions are probably due to infection with a Bartonella species, most often B. henselae and, in some patients, B. quintana. BA is treatable and often cura
- Epidermoid anal cancer in HIV infected patients.
- Clin Oncol (R Coll Radiol). 1996;8(5):319-22. Unique Identifier : AIDSLINE MED/97088114
- Bottomley DM; Aqel N; Selvaratnam G; Phillips RH; Cookridge Hospital, Leeds, UK.
- Anal cancer associated with human immunodeficiency virus (HIV) infection is an unusual clinical situation in which the appropriate management remains unclear. Experience of treatment and follow-up is presented of six patients with histologically confirmed invasive epidermoid anal cancer on a background of HIV infectio
- What's new in AIDS related malignancies? A report from the XI International Conference on AIDS, Vancouver, 7-12 July 1996.
- Clin Oncol (R Coll Radiol). 1996;8(5):336-7. Unique Identifier : AIDSLINE MED/97088119
- Harrison M; Stewart S; Tomlinson D; St Mary's Hospital, London, UK.
- Risks of regional anesthesia--infectious, septic.
- Reg Anesth. 1996 Nov-Dec;21(6 Suppl):57-61. Unique Identifier : AIDSLINE MED/97114701
- Wedel DJ; Horlocker TT; Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota, USA.
- Specificity of aminoglycoside binding to RNA constructs derived from the 16S rRNA decoding region and the HIV-RRE activator region.
- Biochemistry. 1997 Jan 28;36(4):768-79. Unique Identifier : AIDSLINE MED/97172906
- Wang Y; Hamasaki K; Rando RR; Department of Biological Chemistry and Molecular Pharmacology, Harvard; Medical School, Boston, Massachusetts 02115, USA.
- Aminoglycoside antibiotics can bind to many different types of RNA molecules. It was of interest to determine the nature of the selectivity of binding of aminoglycosides to important, biologically relevant RNA targets. Fluorescence anisotropy methods were developed to quantitatively measure aminoglycoside affinities t
- Cocaine, dopamine and the endogenous opioid system.
- J Addict Dis. 1996;15(4):73-96. Unique Identifier : AIDSLINE MED/97098968
- Kreek MJ; Laboratory of the Biology of Addictive Diseases, Rockefeller; University, New York, NY 10021, USA.
- Cocaine addiction and opiate addiction are both major health problems in the United States today. Prospective studies from our Laboratory, which were able to detect the advent of the HIV-1 epidemic in parenteral drug abusers in New York City beginning around 1978, also showed that, fro
- The orphan problem: experience of a sub-Saharan Africa rural population in the AIDS epidemic.
- AIDS Care. 1996 Oct;8(5):509-15. Unique Identifier : AIDSLINE MED/97049172
- Kamali A; Seeley JA; Nunn AJ; Kengeya-Kayondo JF; Ruberantwari A; Mulder DW; Medical Research Council (UK) Programme on AIDS in Uganda, Uganda; Virus Research Institute, Entebbe, Uganda.
- An assessment of the prevalence of orphans and the magnitude of their problems and the extent to which HIV-1 is contributing to this was done in a rural population in South-West Uganda with an HIV-1 seroprevalence of 8% among adults. Slightly over 10% of children aged less than 15
- Gender differences in HIV risk behaviour of injecting drug users in Edinburgh.
- AIDS Care. 1996 Oct;8(5):517-27. Unique Identifier : AIDSLINE MED/97049173
- Davies AG; Dominy NJ; Peters AD; Richardson AM; City Hospital, Edinburgh, UK.
- A multi-site sample of currently-injecting drug users (IDUs) comprising 344 men and 136 women was recruited in Edinburgh. Sixty-seven per cent of the sample said they had at some time used injecting equipment already used by another person and 25% admitted doing so in the 6 months before interview. Whereas women who i
- A community support group for HIV-seropositive drug users: is attendance associated with reductions in risk behaviour? [published erratum appears in AIDS Care 1996 Dec;8(6):716]
- AIDS Care. 1996 Oct;8(5):529-40. Unique Identifier : AIDSLINE MED/97049174
- Greenberg JB; Johnson WD; Fichtner RR; National Center for HIV, STD, and TB Prevention, Centers for Disease; Control and Prevention, Atlanta, GA 30333, USA.
- Although support groups for HIV-seropositive persons are a potential source of emotional support and information, there has been little assessment of such groups as to their role in changing risk behaviour for transmission. The present study combines observations from over 52 group sessions with baseline and follow-up
- Sources of HIV information among injecting drug users: association with gender, ethnicity, and risk behaviour. AIDS Community Demonstration Projects.
- AIDS Care. 1996 Oct;8(5):541-55. Unique Identifier : AIDSLINE MED/97049175
- Wolitski RJ; Fishbein M; Johnson WD; Schnell DJ; Esacove A; National Center for HIV, STD and TB Prevention, Centers for Disease; Control and Prevention, Atlanta, USA. RYW1@CIDHIV2.EM.CDC.GOV
- Sources of HIV information were examined for 774 male and female injecting drug users (IDUs). The majority (80.7%) had received HIV information from one or more sources in the prior 3 months. The most frequently mentioned sources were television (39.9%) and friends or family (22.2%). There were few differences in sour
- Contrasting methods of collecting data on injectors' risk behaviour.
- AIDS Care. 1996 Oct;8(5):557-63. Unique Identifier : AIDSLINE MED/97049176
- McKeganey N; Abel M; Hay G; Centre For Drug Misuse Research, University of Glasgow, UK.
- In this paper two contrasting methods of collecting data on drug injectors needle and syringe sharing practices are considered, namely: direct questions about any previous sharing in the last 6 months, and vignettes in which injectors are asked to indicate whether they would be prepared to share injecting equipment i
- Lay perceptions of risk of HIV infection and the social construction of safer sex: some experiences from Kenya.
- AIDS Care. 1996 Oct;8(5):565-79. Unique Identifier : AIDSLINE MED/97049177
- Nzioka C; Department of Sociology, University of Nairobi, Kenya.
- Safer sex in the context of HIV/AIDS control in Kenya has mainly been promoted through the encouragement of condom use. In this strategy, safer sex is treated as though it is synonymous with condom use. This paper, which is based on ethnographic data drawn from a sample of 29 hetero
- Predicting dentists' willingness to treat HIV-infected patients.
- AIDS Care. 1996 Oct;8(5):581-8. Unique Identifier : AIDSLINE MED/97049178
- Sadowsky D; Kunzel C; Columbia University, School of Dental and Oral Surgery, New York, NY; 10032, USA.
- Access to oral health care is extremely important for those infected with HIV, because oral findings can lead to early detection and improved staging and management of HIV infection. In addition, oral lesions associated with HIV infection are often debilitating, but can be managed effectively with proper oral health c
- People living with HIV infection who attend and do not attend support groups: a pilot study of needs, characteristics and experiences.
- AIDS Care. 1996 Oct;8(5):589-99. Unique Identifier : AIDSLINE MED/97049179
- Kalichman SC; Sikkema KJ; Somlai A; Psychology Department, Georgia State University, Atlanta 30303, USA.; psysck@panther.gsu.edu
- People living with Human Immunodeficiency Virus (HIV) confront a myriad of stressors over the course of their infection. Social support groups offer a means of addressing the support needs of people living with HIV. In the present study, 34 persons who had attended HIV support groups and 29 who had not attended groups
- Effect of didactic teaching and experiential learning on nursing students' AIDS-related knowledge and attitudes.
- AIDS Care. 1996 Oct;8(5):601-8. Unique Identifier : AIDSLINE MED/97049180
- Stiernborg M; Zaldivar SB; Santiago EG; School of Medical Education, University of New South Wales, Sydney,; Australia.
- A total of 562 nursing students from Manila, the Philippines participated in a quasi-experimental design study which assessed the comparative effectiveness of didactic teaching and experiential learning. A 3-hour training session with identical content on AIDS epidemiology, in
- The IXth International Conference on AIDS and STD in Africa.
- AIDS Care. 1996 Oct;8(5):609-16. Unique Identifier : AIDSLINE MED/97049181
- Boahene K; African Foundation for AIDS Prevention and Counselling, Amsterdam, The; Netherlands.
- World Health Organization Global AIDS Statistics.
- AIDS Care. 1996 Oct;8(5):619-23. Unique Identifier : AIDSLINE MED/97049182
- [Fever of unknown origin in patients with HIV infection]
- Enferm Infecc Microbiol Clin. 1996 Dec;14(10):581-5. Unique Identifier : AIDSLINE MED/97170467
- Riera M; Altes J; Homar F; Picco G; Salas A; Leyes M; Cifuentes C; Artigues A; Villalonga C; Servicio de Medicina Interna, Hospital Son Dureta, Palma de Mallorea,; Baleares.
- BACKGROUND: The aim of the study was to describe the etiology and clinical characteristics of fever of uncertain origin (FUO) among HIV-infected patients. METHODS: Prospective analysis of 35 episodes of FUO in HIV-infected patients from Balearic Islands that were studied through established guidelines. RESULTS: Most p
- [Fever and inhabited pulmonary cavity in an AIDS patient]
- Enferm Infecc Microbiol Clin. 1996 Dec;14(10):621-2. Unique Identifier : AIDSLINE MED/97170476
- Aguirre A; Lozano F; Gutierrez MJ; Leon E; Corzo JE; Gomez-Mateos J; Martin E; Seccion de Enfermedades Infecciosas, Hospital Universitario de Valme,; Sevilla.
- [Respiratory cryptosporidiosis (letter; comment)]
- Enferm Infecc Microbiol Clin. 1996 Dec;14(10):627. Unique Identifier : AIDSLINE MED/97170480
- Turrientes MC; Lopez-Velez R
- [Mycobacterium scrofulaceum and AIDS (letter; comment)]
- Enferm Infecc Microbiol Clin. 1996 Dec;14(10):628. Unique Identifier : AIDSLINE MED/97170481
- Lozano F; Nogales C; Corzo JE; Gutierrez MJ; Gomez-Mateos JM
- [Usefulness of immunoblot in the serologic diagnosis of visceral leishmaniasis in patients with the human immunodeficiency virus letter)]
- Enferm Infecc Microbiol Clin. 1996 Dec;14(10):629-30. Unique Identifier : AIDSLINE MED/97170483
- Cardenosa N; Cortes P; Munoz C
- [Cavitated pulmonary nodule due to infection by Pneumocystis carinii (letter)]
- Enferm Infecc Microbiol Clin. 1996 Dec;14(10):633-4. Unique Identifier : AIDSLINE MED/97170487
- Perez-Canal C; Arzuaga-Torre JA; Estirado de Cabo E; Martinez L de Letona J
- [Crusted scabies (Norwegian scabies) in a patient with neuroAIDS letter)]
- Enferm Infecc Microbiol Clin. 1996 Dec;14(10):634-5. Unique Identifier : AIDSLINE MED/97170488
- Font A; Sanchez-Portocarrero J; Mendiburu L; Pena A
- [HIV protease inhibitors]
- Enferm Infecc Microbiol Clin. 1996 Oct;14 Suppl 1:10-4. Unique Identifier : AIDSLINE MED/97095572
- Rubio R; Romeu J; Viciana P; Redondo C; Unidad Infeccion VIH, Hospital 12 de Octubre, Madrid.
- [Other anti-retroviral agents]
- Enferm Infecc Microbiol Clin. 1996 Oct;14 Suppl 1:15-9. Unique Identifier : AIDSLINE MED/97095573
- Clotet B; Labarga P; Portilla J; Echevarria S; Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona.
- [Initial anti-retroviral treatment (therapeutic approach to patients without previous treatment)]
- Enferm Infecc Microbiol Clin. 1996 Oct;14 Suppl 1:20-3. Unique Identifier : AIDSLINE MED/97095574
- Gatell JM; Guerra L; Perez-Elias MJ; Santamaria JM; Hospital Clinic, Barcelona.
- [Anti-retroviral treatment. Approach to previously treated patients]
- Enferm Infecc Microbiol Clin. 1996 Oct;14 Suppl 1:24-30. Unique Identifier : AIDSLINE MED/97095575
- Antela A; Podzamczer D; Ruiz I; Parras F; Hospital Ramon y Cajal, Madrid.
- [Nucleoside analogs inhibiting reverse transcriptase: use in adult patient with HIV infection]
- Enferm Infecc Microbiol Clin. 1996 Oct;14 Suppl 1:3-9. Unique Identifier : AIDSLINE MED/97095571
- Aguirrebengoa K; Mallolas J; Uriz J; Torres Tortosa M; Hospital de Cruces, Baracaldo.
- [Anti-retroviral treatment. Treatment modification: toxicity management]
- Enferm Infecc Microbiol Clin. 1996 Oct;14 Suppl 1:31-5. Unique Identifier : AIDSLINE MED/97095576
- Ocana I; Laguna F; Pulido F; Bascunana A; Hospital General Vall d'Hebron, Barcelona.
- [Anti-retroviral treatment. Treatment in special situations: acute infection, pregnancy, central nervous system involvement, thrombocytopenia, accidental exposure]
- Enferm Infecc Microbiol Clin. 1996 Oct;14 Suppl 1:36-43. Unique Identifier : AIDSLINE MED/97095577
- Iribarren JA; Miralles P; Baraia J; Diez F; Hospital Nuestra Senora de Aranzazu, San Sebastian.
- [Monitoring anti-retroviral treatment]
- Enferm Infecc Microbiol Clin. 1996 Oct;14 Suppl 1:44-50. Unique Identifier : AIDSLINE MED/97095578
- Miro JM; Pumarola T; Soriano V; Bouza E; Hospital Clinic i Provincial, Universidad de Barcelona.
- Gene transfer by DNA/glycosylated polylysine complexes into human blood monocyte-derived macrophages.
- Hum Gene Ther. 1996 Apr 10;7(6):721-9. Unique Identifier : AIDSLINE MED/97077027
- Erbacher P; Bousser MT; Raimond J; Monsigny M; Midoux P; Roche AC; Centre de Biophysique Moleculaire Bat. B, CNRS et Universite; d'Orleans, France.
- Macrophages are putative target cells for expressing an exogenous gene with therapeutical effects. Knowing that macrophages express membrane lectins mediating endocytosis of their ligands, DNA/glycosylated polylysine complexes were used to transfect human blood monocyte-derived macrophages. Monocytes from human periph
- Dimerization of retroviral genomic RNAs: structural and functional implications.
- Biochimie. 1996;78(7):639-53. Unique Identifier : AIDSLINE MED/97114088
- Paillart JC; Marquet R; Skripkin E; Ehresmann C; Ehresmann B; UPR 9002 CNRS, Institut de Biologie Moleculaire et Cellulaire,; Strasbourg, France.
- Retroviruses are a family of widespread small animal viruses at the origin of a diversity of diseases. They share common structural and functional properties such as reverse transcription of their RNA genome and integration of the proviral DNA into the host genome, and have the particularity of packaging a diploid gen
- Transcripts containing a small anti-HIV hammerhead ribozyme that are active in the cell cytoplasm but inactive in vitro as free RNAs.
- Biochimie. 1996;78(7):654-62. Unique Identifier : AIDSLINE MED/97114089
- Domi A; Beaud G; Favre A; Institut Jacques Monod, CNRS, Paris, France.
- In order to study the activity of a hammerhead ribozyme in a cytoplasmic environment. HeLa cells infected with a recombinant vaccinia virus expressing T7 RNA polymerase were contransfected with plasmids expressing the ribozyme and its target RNA nucleotides (nt) +1 to +692 of HIV-1 RNA) under the control of a T7 promo
- Specific interaction between HIV-1 proteinase and 5'-phosphate peptidomimetic derivatives of nucleoside analogues.
- Drug Des Discov. 1995 Aug;13(1):43-54. Unique Identifier : AIDSLINE MED/97037253
- Nillroth U; Besidsky Y; Classon B; Chattopadhyaya J; Ugi I; Danielson UH; Department of Biochemistry, University of Uppsala, Sweden.
- HIV-1 proteinase is shown to interact with 5 -(methoxyglycinyl-S-(N-methylcarbamoylmethyl))thiophosphat e derivatives of 3 -fluoro-3 -deoxythymidine (FLT), 3 -azido-3 -deoxythymidine ( AZT ) and of acyclovir (ACV)
- The bioavailability of oral dosage forms of a new HIV-1 protease inhibitor, KNI-272, in beagle dogs.
- Biopharm Drug Dispos. 1996 Mar;17(2):125-34. Unique Identifier : AIDSLINE MED/97063852
- Kiriyama A; Sugahara M; Yoshikawa Y; Kiso Y; Takada K; Department of Pharmaceutics and Pharmacokinetics, Kyoto Pharmaceutical; University, Yamashina-ku, Japan.
- The bioavailability (BA) of a tripeptide protease inhibitor, KNI-272, which has a strong pharmacological potential for treating human immunodeficiency virus type 1 (HIV-1), has been studied in beagle dogs by administering several oral dosage forms. The tested dosage forms were form 1, plain gelatin capsules; forms 2 a
- Immune activation, allergic drug toxicity and mortality in HIV-positive tuberculosis.
- Tuber Lung Dis. 1996 Dec;77(6):516-23. Unique Identifier : AIDSLINE MED/97191486
- Wallis RS; Helfand MS; Whalen CC; Johnson JL; Mugerwa RD; Vjecha M; Okwera A; Ellner JJ; Case Western Reserve University, Cleveland, Ohio 44106-4984, USA.
- SETTING: Tuberculosis Treatment Center, Kampala, Uganda . OBJECTIVE: HIV-1 affects outcome in pulmonary tuberculosis (TB). Immune mechanisms triggered by Mycobacterium tuberculosis may lead to increased HIV expression and accelerated disease progression. This study was conducted to
- Nosocomial transmission of tuberculosis among mentally-handicapped patients in a long-term care facility.
- Tuber Lung Dis. 1996 Dec;77(6):531-6. Unique Identifier : AIDSLINE MED/97191488
- Lemaitre N; Sougakoff W; Coetmeur D; Vaucel J; Jarlier V; Grosset J; Laboratoire de Bacteriologie, Groupe Hospitalier Pitie-Salpetriere,; Paris, France.
- SETTING: A long-term care facility at Saint-Brieuc hospital, France . OBJECTIVE: To investigate a nosocomial outbreak of culture-positive pulmonary tuberculosis in 6 (40%) of 15 mentally handicapped HIV-seronegative patients. DESIGN: The factors contributing to the outbreak were ana
- Splenectomy in a patients with AIDS, generalized Mycobacterium genavense infection and severe pancytopenia [letter]
- Tuber Lung Dis. 1996 Dec;77(6):569-70. Unique Identifier : AIDSLINE MED/97191496
- Delpire P; Farber CM; Portaels F; Struelens M; Clevenbergh P; Dargent JL; Delpace J; Mehdi A; Van Vooren JP
- Development of antibodies to fetal calf serum with arthus-like reactions in human immunodeficiency virus-infected patients given syngeneic lymphocyte infusions.
- Blood. 1997 Feb 1;89(3):776-9. Unique Identifier : AIDSLINE MED/97180131
- Selvaggi TA; Walker RE; Fleisher TA; Immunology Service, Warren Magnuson Clinical Center, National; Institutes of Health, Bethesda, MD 20892, USA.
- In an attempt to restore immune competence to 12 human immunodeficiency virus-1 (HIV-1)-infected patients, lymphocytes from their HIV-1-uninfected identical twin siblings were cultured in medium supplemented with 5% fetal calf serum (FCS), anti-CD3 antibody, and interleukin-2 (100 IU/mL) for 10 days and then infused i
- Integration patterns of HTLV-I provirus in relation to the clinical course of ATL: frequent clonal change at crisis from indolent disease.
- Blood. 1997 Feb 1;89(3):948-56. Unique Identifier : AIDSLINE MED/97180150
- Tsukasaki K; Tsushima H; Yamamura M; Hata T; Murata K; Maeda T; Atogami S; Sohda H; Momita S; Ideda S; Katamine S; Yamada Y; Kamihira S; Tomonaga M; Department of Hematology, Nagasaki University School of Medicine,; Japan.
- We examined human T-lymphotropic virus type I (HTLV-I) DNA integration in 68 patients with adult T-cell leukemia/ lymphoma ATL) by Southern blotting using EcoRI, which does not cut within the 9 kb of the genome and probes for pX and gag-pol region of HTLV-I. We detected defective proviral integration as a monoclonal b
- Microsatellite instability is rare in B-cell non-Hodgkin's lymphomas.
- Blood. 1997 Feb 1;89(3):975-9. Unique Identifier : AIDSLINE MED/97180153
- Gamberi B; Gaidano G; Parsa N; Carbone A; Roncella S; Knowles DM; Louie DC; Shibata D; Chaganti RS; Dalla-Favera R; Department of Pathology, College of Physicians and Surgeons, Columbia; University, New York 10032, USA.
- Microsatellite instability (MSI), a symptom of defect in DNA mismatch repair function, represents a type of genomic instability frequently detected in many types of cancers. However, the involvement of MSI in non-Hodgkin s lymphomas (NHL) has not been conclusively investigated. In this study, we have tested the presen
- Cytotoxic cell antigen expression in anaplastic large cell lymphomas of T- and null-cell type and Hodgkin's disease: evidence for distinct cellular origin.
- Blood. 1997 Feb 1;89(3):980-9. Unique Identifier : AIDSLINE MED/97180154
- Krenacs L; Wellmann A; Sorbara L; Himmelmann AW; Bagdi E; Jaffe ES; Raffeld M; Hematopathology Section, National Cancer Institute, Bethesda, MD; 20892, USA.
- Anaplastic large cell lymphoma (ALCL) is composed of large, frequently bizarre, cells of T- or null-cell phenotype that show a preferential sinusoidal growth pattern and consistent CD30 positivity. Whether these tumors represent a single entity or several, and what the exact cell origin, is controversial. Recently, gr
- DNA and mRNA sequence of the immune protective DNA ligase I gene match the rev response element of HIV.
- DNA Seq. 1996;6(2):119-21. Unique Identifier : AIDSLINE MED/97063441
- Dandekar T; Koch G; European Molecular Biology Laboratory, Heidelberg, Germany.
- A motif search for DNA and mRNA sequences matching the rev response core element of HIV identified only DNA ligase I to display the element both in DNA and mRNA and to have phylogenetic conservation of it. Genetic impairment of DNA ligase I is already known to lead to severe immunodeficiency in man. A similar impairme
- Multiple endocrine neoplasia type 1 associated with malignant lymphoma and other complications.
- Intern Med. 1996 Nov;35(11):849-54. Unique Identifier : AIDSLINE MED/97123548
- Toshimori H; Okamoto M; Nakatsuru K; Hidaka H; Yamaguchi H; Ushiroda Y; Kisanuki A; Tsubouchi H; Sumiyoshi A; Matsukura S; Third Department of Internal Medicine, Miyazaki Medical College.
- A 49-year-old female with multiple endocrine neoplasia (MEN) type 1 associated with malignant lymphoma, lipoma, functioning adenomatous goiter, non-functioning adrenal tumor, polyneuropathy, postoperative primary hyperparathyroidism, and hepatitis B virus was a human T lymphotropic virus type 1 HTLV-1) carrier. She un
- Neuro-ophthalmic manifestations of AIDS.
- Optom Clin. 1996;5(3-4):113-52. Unique Identifier : AIDSLINE MED/97127760
- Woods AD; Caputo MK; Nova Southeastern University College of Optometry, Fort Lauderdale,; Florida, USA.
- As the incidence of human immunodeficiency virus (HIV) infection increases throughout the world, there becomes a greater probability that the primary care clinician will be confronted by AIDS-related complications. Neuro-ophthalmic problems, including optic neuropathies, motility disturbances, and visual field defects
- Interferon alpha in the therapy of conjunctival lymphoma in an HIV+ patient.
- Eur J Ophthalmol. 1996 Oct-Dec;6(4):475-7. Unique Identifier : AIDSLINE MED/97151614
- Cellini M; Possati GL; Puddu P; Caramazza R; Institute of Ophthalmology, University of Bologna, Italy.
- The authors evaluated the efficacy of interferon-alpha used intralesionally in the therapy of low-grade conjunctival non-Hodgkin lymphoma in an HIV-positive patient. The patient received one intralesional injection of 1,000,000 U of interferon-alpha three times a week for a total of twelve doses. The remission of conj
- Anisotropic rotational diffusion of perdeuterated HIV protease from 15N NMR relaxation measurements at two magnetic fields.
- J Biomol NMR. 1996 Oct;8(3):273-84. Unique Identifier : AIDSLINE MED/97111346
- Tjandra N; Wingfield P; Stahl S; Bax A; Laboratory of Chemical Physics, National Institutes of Diabetes and; Digestive and Kidney Diseases, National Institutes of Health,; Bethesda, MD 20892-0250, USA. nico@speck.niddk.nih.gov
- 15N NMR relaxation times in perdeuterated HIV-1 protease, complexed with the sub-nanomolar inhibitor DMP323, have been measured at 600 and 360 MHz 1H frequency. The relative magnitudes of the principal components of the inertia tensor, calculated from the X-ray coordinates of the protein-drug complex, are 1.0:0.85:0.4
- Biochemical characterization of recombinant equine infectious anemia virus integrase.
- Protein Expr Purif. 1996 Nov;8(3):299-304. Unique Identifier : AIDSLINE MED/97090683
- Engelman A; Division of Human Retrovirology, Dana-Farber Cancer Institute, Boston,; Massachusetts, USA.
- The integrase from equine infectious anemia virus (ELAV) was expressed in Escherichia coli as a polyhistidine fusion protein. The protein was purified under native and denaturing conditions using one-step nickel-affinity chromatography. The purified denatured protein was refolded in the presence of detergent. In vitro
- Expression and biological activity of genetic fusions between MalE, the maltose binding protein from Escherichia coli and portions of CD4, the T-cell receptor of the AIDS virus.
- Protein Expr Purif. 1996 Nov;8(3):319-31. Unique Identifier : AIDSLINE MED/97090686
- Clement JM; Jehanno M; Popescu O; Saurin W; Hofnung M; Unite de Programmation Moleculaire et Toxicologie Genetique CNRS; UA1444), Institut Pasteur, Paris, France.
- Hybrid molecules between MalE, the periplasmic maltose binding protein of Escherichia coli, and CD4, the human T-lymphocyte receptor for the AIDS virus HIV, have been constructed and purified. We show that CD4 can be fused as multiple repeats to both ends of a single MalE molecule. Hybrid proteins are exported into th
- [Diffuse cutaneous leishmaniasis and acquired immunodeficiency syndrome in a Senegalese patient]
- Bull Soc Pathol Exot. 1996;89(4):282-6. Unique Identifier : AIDSLINE MED/97189294
- Ndiaye PB; Develoux M; Dieng MT; Huerre M; Clinique dermatologique, CHU Le Dantee, Dakar, Senegal.
- Tegumentary leishmaniasis cases associated with HIV infections were rarely reported. We present a case of diffuse cutaneous leishmaniasis in a senegalese patient with HIV 1 infection. The diagnosis was supported by a cutaneous biopsy but no Leishmania strain could be isolated by cultures from cutaneous specimens.
- French patient contracts AIDS from surgeon [news]
- BMJ. 1997 Jan 25;314(7076):250. Unique Identifier : AIDSLINE MED/97174825
- Dorozynski A
- The application of allograft bone in foot and ankle surgery.
- J Foot Ankle Surg. 1996 Sep-Oct;35(5):440-51. Unique Identifier : AIDSLINE MED/97073120
- Catanzariti A; Karlock L; Department of Surgery, Podiatry Hospital of Pittsburgh, PA, USA.
- This article presents a synopsis of the classification, processing, basic physiology, clinical applications, complications, and future direction of allogenic bone implantation. Indications and techniques for the use of allogenic bone in the foot and ankle are thoroughly discussed. Additionally, the advantages and disa
- T-lymphocyte subsets in patients with abnormal body weight: longitudinal studies. in anorexia nervosa and obesity.
- Int J Eat Disord. 1996 Nov;20(3):295-305. Unique Identifier : AIDSLINE MED/97068854
- Fink S; Eckert E; Mitchell J; Crosby R; Pomeroy C; University of Minnesota Medical School, Minneapolis, USA.
- OBJECTIVE: In contrast to other types of starvation which are characterized by low CD4+ counts and increased susceptibility to infection, anorexia nervosa is not associated with an increase in infectious complications. To determine why infection risk of anorectics differs from that of other starving populations, we st
- Pediatric HIV infection.
- Curr Opin Pediatr. 1996 Dec;8(6):606-14. Unique Identifier : AIDSLINE MED/97171190
- Lambert JS; University of Maryland, Baltimore School of Medicine, Institute of; Human Virology 21201-1192, USA.
- Our ability to diagnose, treat, and prevent HIV infection in pregnant women and in children has changed dramatically over the last few years. Recent developments include early diagnostic techniques such as polymerase chain reaction, quantitative viral load measurements to assist in estimating disease status and prog
- Morphology, function and pathology of follicular dendritic cells.
- Pathol Int. 1996 Nov;46(11):807-33. Unique Identifier : AIDSLINE MED/97125087
- Imal Y; Yamakawa M; Second Department of Pathology, Yamagata University School of; Medicine, Japan.
- The precise ultrastructural morphology and functions in reactive conditions of lymphoid follicles (LF) and dendritic cells, including follicular dendritic cells (FDC) are reviewed; as well as the pathognomonic role of FDC in some disease conditions and finally, the cellular origin of FDC. In reactive conditions, FDC i
- Establishment and characterization of new human Burkitt's lymphoma cell lines (HBL-7 and HBL-8) that are highly metastatic in SCID mice: a metastatic SCID mouse model of human lymphoma lines.
- Pathol Int. 1996 Sep;46(9):630-8. Unique Identifier : AIDSLINE MED/97061842
- Abe M; Suzuki O; Tasaki K; Abe R; Wakasa H; Department of Pathology, Fukushima Medical College, Japan.
- Two newly established human Burkitt s lymphoma cell lines (HBL-7 and HBL-8) were characterized by immunophenotypic, cytogenetic and molecular studies. Both cell lines were negative for Epstein-Barr virus (EBV) genome and had chromosomal translocation: t(8;14) (q24;q32). Immunoglobulin (Ig) gene rearrangement analyses
- Similarity of neuronal cell injury and death in AIDS dementia and focal cerebral ischemia: potential treatment with NMDA open-channel blockers and nitric oxide-related species.
- Brain Pathol. 1996 Oct;6(4):507-17. Unique Identifier : AIDSLINE MED/97099751
- Lipton SA; Laboratory of Cellular & Molecular Neuroscience, Children's Hospital,; Boston, Massachusetts 02115, USA. lipton-s@a1.tch.harvard.edu
- Using in vitro models, our laboratory in collaboration with those of Pierluigi Nicotera (University of Konstanz, Germany ) and Stan Orrenius (Karolinska Institute) has recently shown that fulminant insults to the nervous system from excitotoxins or free radicals result in neuronal
- Deadly consequences.
- Revolution. 1996 Summer;6(2):40-1. Unique Identifier : AIDSLINE MED/97196196
- Arnold LM
- A longitudinal study of transmission of tuberculosis in a large prison population.
- Am J Respir Crit Care Med. 1997 Feb;155(2):719-25. Unique Identifier : AIDSLINE MED/97184416
- Chaves F; Dronda F; Cave MD; Alonso-Sanz M; Gonzalez-Lopez A; Eisenach KD; Ortega A; Lopez-Cubero L; Fernandez-Martin I; Catalan S; Bates JH; Department of Pathology, University of Arkansas for Medical Sciences,; Little Rock 72205-5484, USA.
- The purpose of this study was to determine the extent of transmission of tuberculosis in a large prison population over an 18-mo period. Restriction-fragment-length polymorphism (RFLP) analysis of isolates of Mycobacterium tuberculosis was performed, using the insertion sequence IS6110 and the plasmid pTBN12. Patients
- Factors associated with microsporidial and cryptosporidial diarrhea in HIV infected patients.
- Parasite. 1996 Dec;3(4):397-401. Unique Identifier : AIDSLINE MED/97186339
- Cornet M; Romand S; Warszawski J; Bouree P; Departement de Parasitologie et Medecine Tropicale, Hopital du; Kremlin-Bicetre, Le Kremlin-Bicetre, France.
- Cryptosporidium and microsporidia are increasingly recognized as important agents of chronic diarrhea in human immunodeficiency virus (HIV) infected patients. These protozoa present clinical and biological similarities but coinfection with these two parasites seems uncommon in a population of diarrheic HIV infected pa
- [Epidemiological portrait of acquired immunodeficiency syndrome and its implications in Benin]
- Sante. 1996 Nov-Dec;6(6):371-6. Unique Identifier : AIDSLINE MED/97189499
- Fourn L; Ducic S; Universite nationale du Benin, Faculte des Sciences de la Sante, Unite; d'enseignement et de recherche en sante publique, Cotonou.
- The HIV/AIDS threat continues in African countries, including the Republic of Benin , during this period of economic crisis which is accentuated by the devaluation of the currency. National statistics from the Ministry of Health indicate a progression of the number of cases seroposit
- Renal ultrasonic findings in sulphadiazine-induced renal failure.
- Br J Radiol. 1996 Oct;69(826):925-8. Unique Identifier : AIDSLINE MED/97190568
- Kane D; Murphy JM; Keating S; Wilson GF; Mulcahy FM; Department of Genito-Urinary Medicine, St James's Hospital, Dublin 8,; Ireland.
- The increased incidence of cerebral toxoplasmosis in AIDS has led to a resurgence in the use of sulphadiazine. One complication of this is acute renal failure secondary to sulphadiazine-induced crystalluria. Three cases are described which demonstrate a spectrum of ultrasound findings ranging from echogenic foci in th
- Lung squamous cell carcinoma presenting with brain metastases in an HIV-positive patient.
- Lung Cancer. 1996 Sep;15(2):245-9. Unique Identifier : AIDSLINE MED/97037345
- Kosmopoulou O; Foukaneli T; Tsavaris N; Agapitos E; Seretis A; Kordossis T; Department of Pathophysiology (AIDS Unit), Athens University Medical; School, Greece.
- The case history of a patient with squamous cell carcinoma of the lung and HIV infection is described, who presented clinically with CNS symptomatology. No association of the tumor with human papilloma virus was found.
- Lung cancer in patients with HIV-infection.
- Lung Cancer. 1996 Nov;15(3):325-39. Unique Identifier : AIDSLINE MED/97118836
- Vyzula R; Remick SC; Division of Medical Oncology, Albany Medical College, NY 12208, USA.
- PURPOSE: To identify and review the clinical characteristics and natural history of lung cancer in HIV-seropositive patients. A secondary objective was to compare the clinical features of HIV-seropositive and HIV-indeterminate lung cancer cases at our institution. PATIENTS AND METHODS: Sixteen patients with HIV infect
- Geographic and ethnic variations in the incidence of childhood cancer.
- Br Med Bull. 1996 Oct;52(4):682-703. Unique Identifier : AIDSLINE MED/97191784
- Stiller CA; Parkin DM; Childhood Cancer Research Group, University of Oxford, UK.
- The total incidence of childhood cancer varies rather little between different regions of the world, with cumulative risk to age 15 nearly always in the range 1.0-2.5 per thousand. Acute lymphoblastic leukaemia, especially in early childhood, is most common in populations of high socio-economic status and is the most
- Getting into the major groove. Protein-RNA interactions.
- Curr Biol. 1996 May 1;6(5):530-2. Unique Identifier : AIDSLINE MED/96398830
- Moras D; Poterszman A; IGBMC, Parc d'Innovation, 1 rue Laurent Fries, BP163 67404 Illkirch,; C.U. de Strasbourg, France.
- The solution structure of the complex between a peptide derived from the bovine immunodeficiency virus tat protein and the TAR RNA to which it binds reveals a new motif in protein-RNA interactions.
- HIV: dendritic cells as embers for the infectious fire.
- Curr Biol. 1996 Jun 1;6(6):655-7. Unique Identifier : AIDSLINE MED/96385428
- Clark EA; Department of Microbiology and Regional Primate Research Center,; University of Washington, Seattle 98195, USA.
- In people with HIV-1, most of the CD4-expressing T cells that produce virus are short-lived and vulnerable to anti-retroviral agents. But the initial fire of HIV-1 infection may begin in, and be maintained by, cells of the dendritic cell lineage.
- Tat-mediated protein delivery can facilitate MHC class I presentation of antigens.
- Mol Biotechnol. 1996 Oct;6(2):105-13. Unique Identifier : AIDSLINE MED/97125062
- Moy P; Daikh Y; Pepinsky B; Thomas D; Fawell S; Barsoum J; Biogen Inc., Cambridge, MA 02142, USA.
- We have previously shown that the tat protein of HIV-1 can be used as a carrier to promote the intracellular delivery of heterologous proteins. Here we have tested if the tat-delivery technology can be used to direct MHC class I presentation of native protein, using ovalbumin (OVA) as a model system. We show that a ta
- Vein irritation from i.v. pentamidine [letter; comment]
- Am J Health Syst Pharm. 1996 Dec 1;53(23):2881-2. Unique Identifier : AIDSLINE MED/97116262
- Herrero Ambrosio A; Gonzalez del Valle L; Gonzalez Garcia J
- Discovery, development and characterization of agents active against the AIDS virus.
- J Recept Signal Transduct Res. 1995 Jan-Mar;15(1-4):609-16. Unique Identifier : AIDSLINE MED/97059646
- Pauwels R; de Bethune MP; Andries K; Stoffels P; Janssen P; De Clercq E; Rega Institute for Medical Research, University of Leuven, Belgium.
- Despite major efforts by academic and pharmaceutical research teams, no definitive prevention or cure of AIDS has been achieved. Nevertheless, this research has yielded important information on how HIV replicates and causes disease. Moreover, several inhibitors, targeted at different steps in the life cycle of HIV, ha
- Determination of the true prevalence of infection with the human T-cell lymphotropic viruses (HTLV-I/II) may require a combination of biomolecular and serological analyses.
- Proc Assoc Am Physicians. 1996 Nov;108(6):444-8. Unique Identifier : AIDSLINE MED/97114633
- Pancake BA; Zucker-Franklin D; Marmor M; Legler PM; Department of Medicine, New York University Medical Center, NY 10016,; USA.
- Infection with the human T-cell lymphotropic virus types I and II HTLV-I/II) usually is determined by tests that detect antibodies to the viral structural proteins. However, recent studies revealed that patients with mycosis fungoides have proviral DNA sequences related to the HTLV transactivating-transforming gene ta
- Determination of interferon-alpha-producing capacity in whole blood cultures from patients with various diseases and from healthy persons.
- J Interferon Cytokine Res. 1996 Nov;16(11):911-8. Unique Identifier : AIDSLINE MED/97093004
- Uno K; Nakano K; Maruo N; Onodera H; Mata H; Kurosu I; Akatani K; Ikegami N; Kishi A; Yasuda Y; Tanaka K; Setoguchi J; Kondo M; Muramatsu S; Kishida T; Louis Pasteur Center for Medical Research, Kyoto, Japan.
- To assess the clinical value of determination of the interferon IFN)-producing capacity of patients, IFN production induced by Sendai virus (HVJ) in vitro was measured in cell cultures of whole blood from patients with various diseases. IFN production in patients with lung cancer, myelodysplastic syndromes, noninsulin
- Role of interferon-stimulated gene ISG-15 in the interferon-omega-mediated inhibition of human immunodeficiency virus replication.
- J Interferon Cytokine Res. 1996 Nov;16(11):919-27. Unique Identifier : AIDSLINE MED/97093005
- Kunzi MS; Pitha PM; Oncology Center, Johns Hopkins University School of Medicine,; Baltimore, MD 21231, USA.
- Interferon-alpha (IFN-alpha) inhibits human immunodeficiency virus (HIV) replication in vivo and in vitro. In this study, we show that IFN-omega (IFN-omega) is also a potent inhibitor of HIV replication in vitro and that both laboratory and primary isolates of HIV-1 are more sensitive to IFN-omega than to IFN-alpha 2.
- The cell surface marker phenotype of macrophages from HIV-1-infected subjects reflects an IL-10-Enriched and IFN-gamma-deprived donor environment.
- J Interferon Cytokine Res. 1996 Nov;16(11):957-62. Unique Identifier : AIDSLINE MED/97093011
- Orlikowsky T; Wang ZQ; Dudhane A; Horowitz H; Conti B; Hoffmann M; Department of Microbiology and Immunology, New York Medical College,; Valhalla 10595, USA.
- T cells depend on costimulation by accessory cells for an immune response. Costimulatory macrophage activity involves the expression of B7 molecules whose expression is upregulated by interferon-gamma (IFN-gamma) and downregulated by interleukin-10 IL-10). The expression of low-affinity Fc gamma IIIR (CD16), in contra
- Induction of inflammatory cytokines in placental monocytes of gravidae infected with the human immunodeficiency virus type 1.
- J Interferon Cytokine Res. 1996 Nov;16(11):963-71. Unique Identifier : AIDSLINE MED/97093012
- Reuben JM; Turpin JA; Lee BN; Doyle M; Gonik B; Jacobson R; Shearer WT; Division of Laboratory Medicine, University of Texas, M.D. Anderson; Cancer Center, Houston 77030, USA.
- Placental mononuclear cells (PMC) are susceptible to infection with the human immunodeficiency virus (HIV). PMC secreted tumor necrosis factor-alpha (TNF-alpha), interleukin-1 beta), and IL-6 among other factors, which, in turn, regulate HIV replication in latently infected cells. We assessed the induction of these cy
- Dosimetry of radionuclide therapy using radiophosphonated antisense oligodeoxynucleotide phosphorothioates based on animal pharmacokinetic and tissue distribution data.
- Antisense Nucleic Acid Drug Dev. 1996 Fall;6(3):215-20. Unique Identifier : AIDSLINE MED/97072741
- Kairemo KJ; Tenhunen M; Jekunen AP; Department of Oncology, Helsinki University Central Hospital, Finland.
- The aim of this study was to evaluate the therapeutic possibilities of radiolabeled antisense oligodeoxynucleotides. The internal radiation dose from known cellular and animal data was calculated, and the suitability of different phosphorus isotopes as labels for oligonucleotides was assessed. We calculated the pharma
- Comparative analysis of five highly conserved target sites within the HIV-1 RNA for their susceptibility to hammerhead ribozyme-mediated cleavage in vitro and in vivo.
- Antisense Nucleic Acid Drug Dev. 1996 Fall;6(3):229-35. Unique Identifier : AIDSLINE MED/97072743
- Ramezani A; Joshi S; Department of Medical Genetics and Microbiology, University of; Toronto, Ontario, Canada.
- Moloney murine leukemia virus (MMLV)-derived pUCMoTiN-based retroviral vectors were engineered to allow constitutive and Tat trans-activator of transcription)-inducible expression of five hammerhead ribozymes targeted against highly conserved sequences within the group antigen (Gag), protease (Pro), reverse transcript
- HIV protease inhibitors and increased bleeding in hemophilia? [news]
- Can Med Assoc J. 1997 Jan 1;156(1):90, 94-5. Unique Identifier : AIDSLINE MED/97159234
- Helal A
- Taking care: caregiving to persons with cancer and AIDS.
- Cancer Nurs. 1997 Feb;20(1):12-22. Unique Identifier : AIDSLINE MED/97185412
- Stetz KM; Brown MA; Seattle Pacific University, School of Health Sciences, Washington; 78119, USA.
- The purpose of this study was to provide an in-depth description of Taking Care, one of the phases of a grounded theory (The Labor of Caregiving) of caregiving for families experiencing life-threatening illnesses such as cancer and acquired immune deficiency syndrome (AIDS). In-depth interviews were conducted with 26
- Zidovudine therapy and left ventricular function and mass in human immunodeficiency virus-infected patients.
- Cardiology. 1997 Jan-Feb;88(1):26-8. Unique Identifier : AIDSLINE MED/97119950
- Cardoso JS; Moura B; Mota-Miranda A; Goncalves FR; Lecour H; Service of Cardiology, Porto Medical School, Hospital de S. Joao,; Portugal.
- Human immunodeficiency virus-infected (HIV) patients frequently present left ventricular dysfunction. Its etiology is not elucidated but zidovudine has been postulated as a possible cause factor. This study is an attempt to clarify this issue by evaluating the effect of zidovudine therapy on left ventricular function
- Selective depletion of rectal lamina propria rather than lymphoid aggregate CD4 lymphocytes in HIV infection.
- Clin Exp Immunol. 1997 Feb;107(2):288-92. Unique Identifier : AIDSLINE MED/97182726
- Clayton F; Snow G; Reka S; Kotler DP; Salt Lake VA Medical Centre and University of Utah School of Medicine,; 84148, USA.
- The goal of this study was to examine the changes in lymphocyte populations in rectal mucosa during HIV infection and to study their relationship to mucosal immunity and to systemic depletion of CD4 lymphocytes. Rectal biopsies from 58 HIV-infected subjects and eight controls were studied. Frozen rectal tissue section
- Mannoproteins of Cryptococcus neoformans induce proliferative response in human peripheral blood mononuclear cells (PBMC) and enhance HIV-1 replication.
- Clin Exp Immunol. 1997 Feb;107(2):293-9. Unique Identifier : AIDSLINE MED/97182727
- Orendi JM; Verheul AF; De Vos NM; Visser MR; Snippe H; Cherniak R; Vaishnav VV; Rijkers GT; Verhoef J; Eijkman-Winkler Institute for Microbiology, Infectious Diseases, and; Inflammation, University Hospital, Utrecht, The Netherlands.
- To investigate the possible role of Cryptococcus neoformans var. neoformans in HIV disease progression, and to identify the responsible cryptococcal components, an in vitro cell culture model was set up to study the C. neoformans-induced enhancement of HIV replication in HIV-1-infected PBMC. Similar to whole C. neofor
- HIV infection of CD45RA+ and CD45RO+ CD4+ T cells.
- Clin Exp Immunol. 1997 Feb;107(2):300-5. Unique Identifier : AIDSLINE MED/97182728
- Helbert MR; Walter J; L'Age J; Beverley PC; Imperial Cancer Research Fund Tumour Immunology Unit, University; College Medical School, London, UK.
- HIV preferentially infects the RO+ memory subset of CD4+ lymphocytes, and these cells are lost earlier in HIV infection than their RA+ counterparts. Although both populations express similar amounts of CD4 and bind the HIV envelope glycoprotein gp120) equally well, calcium signals and CD4 down-regulation subsequent to
- Different Trypanosoma cruzi strains promote neuromyopathic damage mediated by distinct T lymphocyte subsets.
- Clin Exp Immunol. 1997 Feb;107(2):328-34. Unique Identifier : AIDSLINE MED/97182732
- Mirkin GA; Celentano AM; Malchiodi EL; Jones M; Gonzalez Cappa SM; Departamento de Microbiologia, Facultad de Medicina, Universidad de; Buenos Aires, Argentina.
- The proliferative response of CD4 and CD8 T lymphocytes obtained from C3H/HeN mice chronically infected with Trypanosoma cruzi strains that differ in virulence, tropism and immunogenicity, was assayed against skeletal muscle, sciatic nerve and spinal cord homogenates. Although both CD4 and CD8 T lymphocytes from mice
- Identification and characterization of cells infiltrating the graft and aqueous humour in rat corneal allograft rejection.
- Clin Exp Immunol. 1997 Feb;107(2):381-91. Unique Identifier : AIDSLINE MED/97182740
- Larkin DF; Calder VL; Lightman SL; Department of Clinical Science, Institute of Ophthalmology, London,; UK.
- In a rat model of corneal transplantation, Fischer 344 (RT1(lv1)) rats received orthotopic corneal isografts or Wistar-Furth RT1(u)) donor allografts. Rejection was observed in 25 of 26 allograft recipients, at a median time of 18 days, with all isografts surviving > 100 days. Flow cytometric analysis of aqueous humou
- Should we do another test? Decision making in blood banking.
- Clin Lab Med. 1996 Dec;16(4):883-93. Unique Identifier : AIDSLINE MED/97129692
- Hanson M; Memorial Blood Centers of Minnesota, Minneapolis, USA.
- A decision model was developed to evaluate the costs and benefits of further reducing the risk of transfusion-transmitted disease. The model addresses recipient risk factors as well as operational considerations. Application of the model to prior risk reduction decisions documents its validity as a decision-making too
- Legal issues in blood banking. Elements of informed consent.
- Clin Lab Med. 1996 Dec;16(4):931-46. Unique Identifier : AIDSLINE MED/97129695
- Sherman LA; Department of Pathology, Northwestern University Medical School,; Chicago, Illinois, USA.
- In the past, informed consent in pathology was confined chiefly to autopsies. Changes in both consent law and pathology practice led to consent being important in a broader sense in the laboratory. Areas discussed in this article include blood transfusion, tissue specimens, fine needle aspiration, and phlebotomy.
- Indinavir: a pharmacologic and clinical review of a new HIV protease inhibitor.
- Conn Med. 1996 Dec;60(12):723-7. Unique Identifier : AIDSLINE MED/97171721
- Lacy MK; Abriola KP; Department of Pharmacy Research, Hartford Hospital, USA.
- The first one hundred AIDS cases in Hong Kong.
- Chin Med J (Engl). 1996 Jan;109(1):70-6. Unique Identifier : AIDSLINE MED/96333803
- Lee SS; Lo YC; Wong KH; AIDS Unit, Department of Health, Hong Kong.
- OBJECTIVE. To study the clinical and epidemiological characteristics of the first 100 reported AIDS cases in Hong Kong . PATIENTS AND METHODS. The case records of the first 100 AIDS cases reported to the Department of Health were ret
- Species differences in the pharmacokinetics and metabolism of indinavir, a potent human immunodeficiency virus protease inhibitor.
- Drug Metab Dispos. 1996 Oct;24(10):1111-20. Unique Identifier : AIDSLINE MED/97049785
- Lin JH; Chiba M; Balani SK; Chen IW; Kwei GY; Vastag KJ; Nishime JA; Merck Research Laboratories, West Point, PA 19486, USA.
- Indinavir , a potent and specific inhibitor of human immunodeficiency virus protease, is undergoing clinical investigation for the treatment of acquired immunodeficiency syndrome. The studies described herein were designed to characterize the absorptio
- Role of altered metabolism in dideoxynucleoside pharmacokinetics. Studies of 2'-beta-fluoro-2',3'-dideoxyinosine and 2'-beta-fluoro-2',3'-dideoxyadenosine in rats.
- Drug Metab Dispos. 1996 Oct;24(10):1155-61. Unique Identifier : AIDSLINE MED/97049791
- Singhal D; Morgan ME; Anderson BD; Department of Pharmaceutics and Pharmaceutical Chemistry, University; of Utah, Salt Lake City 84108, USA.
- Enzymes of the purine salvage pathway play an important role in altering the in vivo pharmacokinetics of 2 ,3 -dideoxypurine nucleosides. This study examines the pharmacokinetics of enzyme-resistant 2 -beta-fluoro analogues of 2 ,3 -dideoxyinosine ddI) and 2 ,3 -dideoxyadenosine (ddA). 2 -beta-Fluoro-2 ,3 -dideoxyinos
- Didanosine. An update on its antiviral activity, pharmacokinetic properties and therapeutic efficacy in the management of HIV disease.
- Drugs. 1996 Dec;52(6):928-62. Unique Identifier : AIDSLINE MED/97116073
- Perry CM; Balfour JA; Adis International Limited, Auckland, New Zealand.
- Didanosine is a dideoxynucleoside analogue, which is phosphorylated to the active metabolite dideoxyadenosine triphosphate (ddATP) intracellularly. At therapeutic concentrations, ddATP inhibits HIV replication by inhibiting HIV reverse transcriptase. Didanosine is established as a first-line treatment for patients wit
- Analysis of recombinant and native CD4 by one- and two-dimensional gel electrophoresis.
- Electrophoresis. 1996 Jan;17(1):227-34. Unique Identifier : AIDSLINE MED/97063679
- Lynch GW; Dearden M; Sloane AJ; Humphery-Smith I; Cunningham AL; Department of Virology, ICPMR, University of Sydney, Westmead; Hospital, Westmead and National Centre for HIV Virology Research,; Australia. GARRYL@Westmed.WH.SU.E-DU.AU
- Knowledge of CD4 conformation within the membranes of human lymphoid and monocytoid cells is essential for a clear understanding of its function as a ligand for major histocompatibility complex II (MHC) molecules in T cell activation and for gp120 in human immunodeficiency virus (HIV) infection. The charge and structu
- Oncogenic potential of TAR RNA binding protein TRBP and its regulatory interaction with RNA-dependent protein kinase PKR.
- EMBO J. 1997 Feb 3;16(3):611-24. Unique Identifier : AIDSLINE MED/97186727
- Benkirane M; Neuveut C; Chun RF; Smith SM; Samuel CE; Gatignol A; Jeang KT; Laboratory of Molecular Microbiology, NIAID, NIH, Bethesda, MD; 20892-0460, USA.
- TAR RNA binding protein (TRBP) belongs to an RNA binding protein family that includes the double-stranded RNA-activated protein kinase (PKR), Drosophila Staufen and Xenopus xlrbpa. One member of this family, PKR, is a serine/threonine kinase which has anti-viral and anti-proliferative effects. In this study we show th
- Thrombotic microangiopathy related to infection in an HIV-positive patient [letter]
- Eur J Clin Microbiol Infect Dis. 1996 Mar;15(3):254-6. Unique Identifier : AIDSLINE MED/96308982
- Mayo J; Collazos J; Martinez E
- Systemic Penicillium marneffei infection in a German AIDS patient [letter]
- Eur J Clin Microbiol Infect Dis. 1996 Mar;15(3):256-9. Unique Identifier : AIDSLINE MED/96308983
- Sobottka I; Albrecht H; Mack D; Stellbrink HJ; van Lunzen J; Tintelnot K; Laufs R
- Frequency of subclinical visceral leishmaniasis in HIV-1-infected patients in Spain [letter]
- Eur J Clin Microbiol Infect Dis. 1996 Mar;15(3):263-4. Unique Identifier : AIDSLINE MED/96308986
- Pineda JA; Hernandez-Quero J; Gallardo JA; Lopez-Ruz MA; Martinez-Perez MA; Macias J; Lissen E
- Cytokine profiles in bronchoalveolar lavage fluid and blood in HIV-seronegative patients with Pneumocystis carinii pneumonia.
- Eur J Clin Invest. 1996 Feb;26(2):159-66. Unique Identifier : AIDSLINE MED/97060205
- Perenboom RM; van Schijndel AC; Beckers P; Sauerwein R; Van Hamersvelt HW; Festen J; Gallati H; van der Meer JW; Department of General Internal Medicine, University Hospital Nijmegen,; The Netherlands.
- Concentrations and ex vivo production of interleukin-1beta IL-1beta), tumour necrosis factor-alpha (TNF), interleukin-6 IL-6), interleukin-1 receptor antagonist (IL-1RA) and TNF soluble receptors were followed in bronchoalveolar lavage (BAL) fluid and blood from 10 HIV-seronegative patients with Pneumocystis carinii p
- Apoptosis in AIDS. Genetic control and relevance for AIDS pathogenesis.
- Biochem Soc Trans. 1996 Nov;24(4):1055-8. Unique Identifier : AIDSLINE MED/97123262
- Gougeon ML; Departement SIDA et Retrovirus, Institut Pasteur, Paris, France.
- Nonclinical toxicology studies with zidovudine: acute, subacute, and chronic toxicity in rodents, dogs, and monkeys.
- Fundam Appl Toxicol. 1996 Aug;32(2):129-39. Unique Identifier : AIDSLINE MED/97079605
- Ayers KM; Tucker WE Jr.; Hajian G; De Miranda P; Glaxo Wellcome, Inc., Research Triangle Park, North Carolina 27709,; USA.
- In single dose acute toxicity studies in CD-1 mice and CD rats, the median lethal dose (MLD) for zidovudine (ZDV) was > 750 mg/kg after iv dosing and > 3000 mg/kg after po administration recommended human dose is 100 mg every 4 hr while awake). Because of the short half-life in rats (0.8 hr), dogs (1.0 hr), and monkey
- Nonclinical toxicology studies with zidovudine: reproductive toxicity studies in rats and rabbits.
- Fundam Appl Toxicol. 1996 Aug;32(2):140-7. Unique Identifier : AIDSLINE MED/97079606
- Greene JA; Ayers KM; Tucker WE Jr.; de Miranda P; Glaxo Wellcome, Inc., Research Triangle Park, NC 27709, USA.
- Zidovudine (ZDV) was evaluated for adverse effects on reproduction and fetal development in animal test species. Standard preclinical tests for reproduction and fertility, developmental toxicity, and postnatal toxicity were conducted in CD (Sprague-Dawley) rats and a developmental toxicity study was conducted in
- Nonclinical toxicology studies with zidovudine: genetic toxicity tests and carcinogenicity bioassays in mice and rats.
- Fundam Appl Toxicol. 1996 Aug;32(2):148-58. Unique Identifier : AIDSLINE MED/97079607
- Ayers KM; Clive D; Tucker WE Jr.; Hajian G; de Miranda P; Glaxo Wellcome, Inc., Research Triangle Park, North Carolina 27709,; USA.
- Zidovudine (ZDV), an antiviral drug active in the treatment of acquired immunodeficiency syndrome (recommended human dose, 100 mg every 4 hr while awake), was evaluated for mutagenic and carcinogenic potential in a battery of short-term in vitro and in vivo assays and in lifetime studies in mice and rats. In L5178Y mo
- Helical epitopes determined by low-stringency antibody screening of a combinatorial peptide library.
- FASEB J. 1997 Feb;11(2):147-53. Unique Identifier : AIDSLINE MED/97192138
- Stern B; Denisova G; Buyaner D; Raviv D; Gershoni JM; Department of Cell Research and Immunology, George S. Wise Faculty of; Life Sciences, Tel Aviv University, Israel.
- Combinatorial phage display peptide libraries are routinely used to map epitopes of specific monoclonal antibodies. In this study we illustrate that these libraries can be used in the analysis of protein structure. By screening libraries at low stringency, a collection of phages can be obtained. These are characterize
- [Prolonged clinical remission of cholangitis in early human immunodeficiency virus infection after surgical biliary derivation]
- Gastroenterol Clin Biol. 1996;20(6-7):593-6. Unique Identifier : AIDSLINE MED/97035926
- Di Martino V; Vitte RL; Eugene C; Chamiot-Prieur C; Bergue A; Oberlin P; Unite de Gastroenterologie, Centre Hospitalier Intercommunal, Poissy.
- During the acquired immunodeficiency syndrome, most cases of cholangitis develop at an advanced stage of disease. We report a case of cholangitis in a 47-year-old homosexual man, stage IIa according to Center of Disease Control classification. An isolated jaundice was the first manifestation of the disease. The number
- [Clinical and radiological aspects of tuberculous splenic abscesses. Presentation of 3 cases]
- Gastroenterol Clin Biol. 1996;20(6-7):597-600. Unique Identifier : AIDSLINE MED/97035927
- Abitbol V; Paupard T; Etienney I; Patey O; Guez C; Oberlin P; Cattan D; Service d'Hepato-Gastroenterologie, Centre Hospitalier, Villeneuve; St-Georges.
- Tuberculous splenic abscess is an exceptional disease with silent presentation in disseminated tuberculosis infection. Imaging procedures allow to suspect this diagnosis in case of multilocular nodules of the spleen, or unilocular pseudotumoral macronodule. We report three cases of tuberculous splenic abscesses in two
- [Herpetic esophagitis disclosing primary HIV infection (letter)]
- Gastroenterol Clin Biol. 1996;20(6-7):612-3. Unique Identifier : AIDSLINE MED/97035935
- Blain A; Bellaiche G; Choudat L; Slama JL; Ley G; Paugam B
- Immunobiology of cartilage transplants for functional nasal reconstruction.
- Facial Plast Surg. 1995 Jul;11(3):237-43. Unique Identifier : AIDSLINE MED/97198568
- Bujia J; Wustrow TP; Hammer C; Department of Otolaryngology, Head and Neck Surgery,; Ludwig-Maximilians University of Munich, Germany.
- Oxidative stress during viral infection: a review.
- Free Radic Biol Med. 1996;21(5):641-9. Unique Identifier : AIDSLINE MED/97046746
- Schwarz KB; Department of Pediatrics, Johns Hopkins Medical Institutions,; Baltimore, Maryland, USA.
- The purpose of this review is to analyze the role of reactive oxygen species (ROS) in the pathogenesis of viral infections, an area of research that has recently gained momentum given the accumulation of evidence regarding the role of ROS in the pathogenesis of infection with the human immunodeficiency virus HIV). Att
- Investigation of chronic diarrhoea in acquired immunodeficiency syndrome. A prospective study of 155 patients.
- Gut. 1996 Dec;39(96):824-32. Unique Identifier : AIDSLINE MED/97190704
- Blanshard C; Francis N; Gazzard BG; Chelsea and Westminster Hospital, London.
- BACKGROUND AND AIMS: The optimum diagnostic investigation for patients with acquired immunodeficiency syndrome (AIDS) and diarrhoea is not known. Often no pathogen is detected and it is unclear whether this is because pathogens are absent in some patients or the investigations used fail to detect them. The hypothesis
- Hope for haemophilic patients with hepatitis [comment]
- Gut. 1996 Dec;39(96):887-8. Unique Identifier : AIDSLINE MED/97190718
- Lee CA; Haemophilia Centre, Royal Free Hospital, London.
- Primary effusion Burkitt's lymphoma with t(8;22) in a patient with hepatitis C virus-related cirrhosis.
- Hum Pathol. 1997 Jan;28(1):101-4. Unique Identifier : AIDSLINE MED/97165947
- Ascoli V; Lo Coco F; Artini M; Levrero M; Fruscalzo A; Mecucci C; Dipartimento di Medicina Sperimentale e Patologia, Universita La; Sapienza, Roma, Italy.
- Hepatitis C virus (HCV) infection may be complicated by non-Hodgkin s lymphoma through yet unknown pathogenetic mechanisms. We describe the case of a patient with HCV-related cirrhosis who developed a primary effusion lymphoma (PEL) of Burkitt s type confined to the peritoneal cavi
- The clinical utility of viral load monitoring in HIV infection: strengths and limitations [editorial]
- Genitourin Med. 1996 Dec;72(6):393-5. Unique Identifier : AIDSLINE MED/97190672
- Erbelding EJ; Quinn TC
- Molecular immunopathogenesis of HIV infection.
- Genitourin Med. 1996 Dec;72(6):408-18. Unique Identifier : AIDSLINE MED/97190676
- Ng TT; Pinching AJ; Guntermann C; Morrow WJ; Department of Immunology, St Bartholomew's and the Royal London School; of Medicine and Dentistry, UK.
- Uveitis associated with rifabutin and macrolide therapy for Mycobacterium avium intracellulare infection in AIDS patients.
- Genitourin Med. 1996 Dec;72(6):419-21. Unique Identifier : AIDSLINE MED/97190677
- Kelleher P; Helbert M; Sweeney J; Anderson J; Parkin J; Pinching A; Department of Immunology, Royal Hospitals NHS Trust, London.
- OBJECTIVE: Uveitis has been increasingly recognised as a side effect of rifabutin regimens in the prophylaxis and treatment of Mycobacterium avium intracellulare (MAI) infection. This study describes the clinical features and analyses the factors associated with rifabutin induced uveitis. DESIGN: Retrospective observa
- Gonorrhoea in men: clinical and diagnostic aspects.
- Genitourin Med. 1996 Dec;72(6):422-6. Unique Identifier : AIDSLINE MED/97190678
- Sherrard J; Barlow D; Department of Genitourinary Medicine, Radcliffe Infirmary, UK.
- AIM: To review the features of gonococcal infection in men in the 1990s. METHODS: A retrospective study of all men with gonorrhoea presenting to an inner city department of genitourinary medicine in the years 1990 to 1992. RESULTS: 1749 cases of gonorrhoea were seen in 1382 men. A high incidence of gonorrhoea was foun
- Aspergillus infection of the epiglottis in a HIV positive patient.
- Genitourin Med. 1996 Dec;72(6):431-2. Unique Identifier : AIDSLINE MED/97190681
- Sriskandabalan P; Roy RB; Royal Bournemouth Hospital, UK.
- Microsporidia: a new sexually transmissable cause of urethritis [letter]
- Genitourin Med. 1996 Dec;72(6):445. Unique Identifier : AIDSLINE MED/97190686
- Birthistle K; Moore P; Hay P
- Cytomegalovirus retinitis in a healthy antiretroviral naive HIV positive male with a CD4 count of 277/mm3 [letter]
- Genitourin Med. 1996 Dec;72(6):446-7. Unique Identifier : AIDSLINE MED/97190688
- Fairley I; Waugh MA
- Acute cytomegalovirus prostatitis in AIDS [letter]
- Genitourin Med. 1996 Dec;72(6):447-8. Unique Identifier : AIDSLINE MED/97190689
- Mastroianni A; Coronado O; Manfredi R; Chiodo F; Scarani P
- Systemic lupus erythematosus features in an AIDS patient: diagnostic problems in an African rural hospital [letter]
- Genitourin Med. 1996 Dec;72(6):448-9. Unique Identifier : AIDSLINE MED/97190690
- Falaschi F; Ansaloni L
- Crusted ("Norwegian") scabies in a specialist HIV unit [letter; comment]
- Genitourin Med. 1996 Dec;72(6):453. Unique Identifier : AIDSLINE MED/97190694
- Nandwani R; Pozniak AL; Fuller LC; Wade J
- Caregivers fear of contagion [letter; comment]
- Image J Nurs Sch. 1996 Spring;28(1):9. Unique Identifier : AIDSLINE MED/97063788
- Bennett JA
- HIV-1-specific cell-mediated immunity is enhanced by co-inoculation of TCA3 expression plasmid with DNA vaccine.
- Immunology. 1997 Jan;90(1):1-6. Unique Identifier : AIDSLINE MED/97190746
- Tsuji T; Fukushima J; Hamajima K; Ishii N; Aoki I; Bukawa H; Ishigatsubo Y; Tani K; Okubo T; Dorf ME; Okuda K; Department of Bacteriology, Yokohama City University School of; Medicine, Japan.
- We developed a candidate DNA vaccine designated pCMV160IIIB with pcREV (pCMV160IIIB/REV) that encodes gp160 of human immunodeficiency virus (HIV)-1IIIB and Rev driven by the cytomegalovirus (CMV) promotor. This vaccine induced both HIV-1-specific antibodies and cytotoxic T lymphocy
- A human CD4+ T-cell line expresses functional CD64 (Fc gamma RI), CD32 (Fc gamma RII), and CD16 (Fc gamma RIII) receptors but these do not enhance the infectivity of HIV-1-IgG complexes.
- Immunology. 1997 Jan;90(1):109-14. Unique Identifier : AIDSLINE MED/97190761
- McLain L; Dimmock NJ; Department of Biological Sciences, University of Warwick, Coventry,; UK.
- T cells do not generally express Fc receptors (FcRs). However, we report here that C8166 cells, a human CD4+ T lymphoblastoid cell line, widely used in research into the human immunodeficiency virus type 1 (HIV-1), expressed CD64 (Fc gamma RI), CD32 (Fc gamma RII), and CD16 (Fc gamma RIII) on the plasma membrane as sh
- Recovery from retrovirus-induced immune suppression in BDP/J mice: dominance of the "regressor' phenotype.
- Immunology. 1997 Jan;90(1):7-13. Unique Identifier : AIDSLINE MED/97190747
- Gilmore GL; Department of Immunology, Medical Biology Institute, La Jolla, CA,; USA.
- Murine acquired immune deficiency syndrome (MAIDS) is an immunosuppressive disease of mice induced by infection with the LP-BM5 murine leukemia virus (MuLV) retrovirus isolate. Certain inbred strains of mice are resistant to disease, but F1 crosses between sensitive and resistant strains are predominantly sensitive to
- Pristane-induced arthritis is CD4+ T-cell dependent.
- Immunology. 1997 Jan;90(1):81-6. Unique Identifier : AIDSLINE MED/97190757
- Stasiuk LM; Ghoraishian M; Elson CJ; Thompson SJ; Department of Pathology and Microbiology, University of Bristol, UK.
- The development of arthritis induced in mice by intraperitoneal injection of the non-antigenic mineral oil pristane 2,6,10,14-tetramethylpent