1997
- Synthesis, antiviral and antiproliferative activity of a new class of 5-(alkyl or arylthio)-6-vinyl uracils.
- Anticancer Drug Des. 1996 Dec;11(8):597-609. Unique Identifier : AIDSLINE MED/97175088
- Baraldi PG; Cacciari B; Romagnoli R; Spalluto G; Garuti L; Roberti M; Pani A; Perra G; Scintu F; Pinna N; Musiu C; La Colla P
- Uracil derivatives bearing substituted or unsubstituted vinyl groups at position C6 and alkyl- or arylthio groups at position C5 were synthesized and tested in vitro for antiviral and antiproliferative activity. None of the compounds were active against HIV-1. However, some of them inhibited the proliferation of leuke
- Naltrexone prevents ethanol-induced changes in rat thymus.
- Alcohol. 1996 Nov-Dec;13(6):533-7. Unique Identifier : AIDSLINE MED/97107198
- Budec M; Leposavic G; Karapetrovic B; Kosec D; Institute for Medical Research, Beograd, Yugoslavia.
- Ethanol is known to suppress the immune response, but the underlying mechanism accounting for the immunosuppression is not clearly elucidated yet. The purpose of this study was to investigate the effect of a single dose of ethanol on relative proportion of the four major rat thymocyte subsets and possible mechanism of
- Shedding of HIV-1 in the genital tract [editorial]
- AIDS. 1996 Oct;10(12):1305-15. Unique Identifier : AIDSLINE MED/97057719
- Mostad SB; Kreiss JK
- RANTES, MIP-1 alpha and MIP-1 beta are not involved in the inhibition of HIV-1SF33 replication mediated by CD8+ T-cell clones.
- AIDS. 1996 Oct;10(12):1317-21. Unique Identifier : AIDSLINE MED/97057720
- Paliard X; Lee AY; Walker CM; Chiron Corporation, Virology and Vaccine Development, Emeryville, CA; 94608, USA.
- OBJECTIVE: To determine whether CD8+ cells inhibit HIV replication in vitro through the chemokines RANTES, macrophage inflammatory protein (MIP)-1 alpha and MIP-1 beta. DESIGN AND METHODS: CD8+ T-cell clones were screened for their ability to inhibit HIV-1SF33 replication in CD4+ cells using p24 antigen and HIV RNA le
- Functional interaction between the HIV-1 Tat transactivator and the inhibitory domain of the Oct-2 cellular transcription factor.
- AIDS. 1996 Oct;10(12):1323-9. Unique Identifier : AIDSLINE MED/97057721
- Liu YZ; Lania L; Latchman DS; Department of Molecular Pathology, University College London Medical; School, UK.
- OBJECTIVES: To examine the interaction of the HIV Tat protein and the inhibitory domain of the cellular transcription factor Oct-2. DESIGN: HIV reporter plasmids were co-transfected with expression vectors encoding wild-type and mutant Tat proteins and vectors encoding the inhibitory domain either alone or linked to a
- Chimeric viruses between SIVmac and various HIV-1 isolates have biological properties that are similar to those of the parental HIV-1.
- AIDS. 1996 Oct;10(12):1331-7. Unique Identifier : AIDSLINE MED/97057722
- Kuwata T; Shioda T; Igarashi T; Ido E; Ibuki K; Enose Y; Stahl-Hennig C; Hunsmann G; Miura T; Hayami M; Institute for Virus Research, Kyoto University, Japan.
- OBJECTIVE: To examine the biological properties of HIV-1/SIVmac chimeric viruses from HIV-1 isolates that have different replication rates, cell tropisms and cytopathicities. DESIGN AND METHODS: Four chimeric viruses with gag, pol, vif, vpx, nef and long terminal repeats of SIVmax and vpr, tat, rev, vpu and env of var
- Buspirone, a serotonin receptor agonist, increases CD4 T-cell counts and modulates the immune system in HIV-seropositive subjects.
- AIDS. 1996 Oct;10(12):1339-47. Unique Identifier : AIDSLINE MED/97057723
- Hofmann B; Afzelius P; Iversen J; Kronborg G; Aabech P; Benfield T; Dybkjaer E; Nielsen JO; Department of Clinical Immunology, Copenhagen University Hospitals,; Hvidovre, Denmark.
- OBJECTIVE: We have previously shown that drugs that decrease intracellular cAMP levels increase/restore the proliferative and cytotoxic capacity of T cells from HIV-seropositive subjects in vitro. Buspirone, a serotonin receptor agonist, indirectly decreases intracellular cAMP levels in T cells and has the same increa
- Inflammatory cytokines and inhibitors in HIV infection: correlation between interleukin-1 receptor antagonist and weight loss.
- AIDS. 1996 Oct;10(12):1349-56. Unique Identifier : AIDSLINE MED/97057724
- Rimaniol AC; Zylberberg H; Zavala F; Viard JP; Institut National de la Sante et de la Recherche Medicale INSERM) U25,; Necker Hospital, Paris, France.
- OBJECTIVE: To determine serum levels of the interleukin-1 receptor antagonist (IL-1Ra), together with cytokines, other cytokine inhibitors and markers of immune activation in HIV-infected patients. METHODS: Sixty-one HIV-patients were classified into Center for Disease Control and Prevention (CDC) groups A (n = 14), B
- Pilot study of the efficacy of atevirdine in the treatment of AIDS dementia complex.
- AIDS. 1996 Oct;10(12):1357-60. Unique Identifier : AIDSLINE MED/97057725
- Brew BJ; Dunbar N; Druett JA; Freund J; Ward P; National Centre in HIV Epidemiology and Clinical Research,; Darlinghurst, Sydney, Australia.
- OBJECTIVES: To determine the efficacy of the non-nucleoside reverse transcriptase inhibitor atevirdine in the treatment of AIDS dementia complex (ADC). DESIGN: Open label pilot study. METHODS: Ten patients with ADC (stage 1 or 2) who were intolerant to zidovudine or dideoxyinosine,
- The effect of zidovudine dose on the formation of intracellular phosphorylated metabolites.
- AIDS. 1996 Oct;10(12):1361-7. Unique Identifier : AIDSLINE MED/97057726
- Barry MG; Khoo SH; Veal GJ; Hoggard PG; Gibbons SE; Wilkins EG; Williams O; Breckenridge AM; Back DJ; Department of Pharmacology and Therapeutics, University of Liverpool,; UK.
- OBJECTIVES: Zidovudine (ZDV) requires intracellular phosphorylation to ZDV triphosphate (ZDV-TP) prior to the inhibition of HIV replication. The effect of ZDV dose on the formation of intracellular phosphorylated metabolites may help define the optimum daily dose of ZDV, which is still unknown. DESIGN AND METHODS: The
- Itraconazole cyclodextrin solution for fluconazole-refractory oropharyngeal candidiasis in AIDS: correlation of clinical response with in vitro susceptibility.
- AIDS. 1996 Oct;10(12):1369-76. Unique Identifier : AIDSLINE MED/97057727
- Phillips P; Zemcov J; Mahmood W; Montaner JS; Craib K; Clarke AM; AIDS Research Program, St Paul's Hospital, Vancouver, Canada.
- OBJECTIVE: To evaluate the efficacy of itraconazole cyclodextrin solution in fluconazole-refractory oropharyngeal candidiasis OPC), and to correlate clinical outcome with in vitro susceptibility and serum azole levels. DESIGN: A prospective, open-label, intervention study. SETTING: A university hospital, which serves
- Energy balance in asymptomatic HIV infection.
- AIDS. 1996 Oct;10(12):1377-84. Unique Identifier : AIDSLINE MED/97057728
- Sharpstone DR; Murray CP; Ross HM; Hancock MR; Phelan MS; Crane RC; Menzies IS; Reaveley DA; Lepri AC; Nelson MR; Gazzard BG; Department of HIV/Genito-Urinary Medicine, Chelsea and Westminster; Hospital, London, UK.
- OBJECTIVES: Body weight is regulated by the balance between energy intake and energy expenditure, but the influence of HIV infection on energy balance has not been fully examined. The main objectives of this study were (1) to assess the effect of HIV on energy balance, (2) to examine the relationship of parameters of
- Intestinal inflammation, ileal structure and function in HIV.
- AIDS. 1996 Oct;10(12):1385-91. Unique Identifier : AIDSLINE MED/97057729
- Bjarnason I; Sharpstone DR; Francis N; Marker A; Taylor C; Barrett M; Macpherson A; Baldwin C; Menzies IS; Crane RC; Smith T; Pozniak A; Gazzard BG; Department of Clinical Biochemistry, King's College School of Medicine; and Dentistry, London, UK.
- OBJECTIVES: This study examines small intestinal absorption-permeability, intestinal inflammation and ileal structure and function in HIV-positive male homosexuals. METHODS: Thirty HIV-seropositive male homosexuals at various stages of disease underwent intestinal absorption permeability and 111indium leukocyte studie
- Toxoplasmic encephalitis in HIV-infected persons: risk factors and trends. The Adult/Adolescent Spectrum of Disease Group.
- AIDS. 1996 Oct;10(12):1393-9. Unique Identifier : AIDSLINE MED/97057730
- Jones JL; Hanson DL; Chu SY; Ciesielski CA; Kaplan JE; Ward JW; Navin TR; Division of HIV/AIDS Prevention, Centers for Disease Control and; Prevention, Atlanta, Georgia 30333, USA.
- OBJECTIVE: To evaluate the incidence of and risk factors for toxoplasmic encephalitis among HIV-infected persons. DESIGN: Medical facility-based prospective medical record reviews of consecutive patients. METHODS: We analysed data collected from January 1990 through August 1995 in more than 90 inpatient and outpatient
- Declining incidence and later occurrence of Kaposi's sarcoma among persons with AIDS in Australia: the Australian AIDS cohort.
- AIDS. 1996 Oct;10(12):1401-6. Unique Identifier : AIDSLINE MED/97057731
- Dore GJ; Li Y; Grulich AE; Hoy JF; Mallal SA; Mijch AM; French MA; Cooper DA; Kaldor JM; National Centre in HIV Epidemiology and Clinical Research, University; of New South Wales, Sydney, Australia.
- OBJECTIVE: To explore trends in cumulative incidence of Kaposi s sarcoma (KS) and the level of immunodeficiency at KS diagnosis among people with AIDS in Australia . SETTING: Three hospital-based HIV units. STUDY POPULATION: Retrospective cohort of 2580 people diagnosed with AIDS
- Incidence and spectrum of severe medical complications among hospitalized HIV-seronegative and HIV-seropositive narcotic drug users [see comments]
- AIDS. 1996 Oct;10(12):1407-14. Unique Identifier : AIDSLINE MED/97057732
- Scheidegger C; Zimmerli W; Department of Internal Medicine, University Hospital of Basel,; Switzerland.
- OBJECTIVE: To examine differences in the incidence and spectrum of diseases, as well as duration of inpatient stay, between HIV-seronegative and HIV-seropositive narcotic drug, users (NDU). DESIGN: Retrospective analysis of 9 years of experience. Data collection by chart review using preset criteria for diagnoses. Est
- Changes in male sexual behaviour in response to the AIDS epidemic: evidence from a cohort study in urban Tanzania.
- AIDS. 1996 Oct;10(12):1415-20. Unique Identifier : AIDSLINE MED/97057733
- Ng'weshemi JZ; Boerma JT; Pool R; Barongo L; Senkoro K; Maswe M; Isingo R; Schapink D; Nnko S; Borgdorff MW; Tanzania-Netherlands Project to Support AIDS Control in Mwanza Region; (TANESA), Mwanza, Tanzania.
- OBJECTIVE: To examine changes in sexual behaviour among men in urban Tanzania . DESIGN: An observational cohort study among factory workers during 1991-1994. METHODS: Data from five follow-up visits with structured questionnaire-guided interviews and biomedical data were analysed
- Quality of life in HIV disease as measured by the McGill quality of life questionnaire.
- AIDS. 1996 Oct;10(12):1421-7. Unique Identifier : AIDSLINE MED/97057734
- Cohen SR; Hassan SA; Lapointe BJ; Mount BM; Department of Oncology, McGill University, Montreal, Quebec, Canada.
- OBJECTIVE: To test the acceptability, validity, and internal consistency reliability of the McGill quality of life questionnaire (MQOL) for persons living with HIV/AIDS. DESIGN: The validity of MQOL was tested by having HIV-seropositive outpatients complete the 16-item MQOL, a single-item scale (SIS) measuring overall
- Can we reduce the burden of morbidity in HIV-infected injecting drug users? [editorial; comment]
- AIDS. 1996 Oct;10(12):1429-30. Unique Identifier : AIDSLINE MED/97057735
- Selwyn PA
- Serum levels of RANTES and MIP-1 alpha in HIV-positive long-term survivors and progressor patients [letter]
- AIDS. 1996 Oct;10(12):1431-2. Unique Identifier : AIDSLINE MED/97057736
- Zanussi S; D'Andrea M; Simonelli C; Tirelli U; De Paoli P
- Chemokine production in HIV-seropositive long-term asymptomatic individuals [letter]
- AIDS. 1996 Oct;10(12):1432-3. Unique Identifier : AIDSLINE MED/97057737
- Clerici M; Balotta C; Trabattoni D; Papagno L; Ruzzante S; Rusconi S; Fusi ML; Colombo MC; Galli M
- CD8+ T-cell-mediated suppression of HIV-1 infection may not be due to chemokines RANTES, MIP-1 alpha and MIP-1 beta [letter]
- AIDS. 1996 Oct;10(12):1434-5. Unique Identifier : AIDSLINE MED/97057738
- Chen Y; Gupta P
- RANTES, MIP and interleukin-16 in HIV infection [letter]
- AIDS. 1996 Oct;10(12):1435-6. Unique Identifier : AIDSLINE MED/97057739
- Blazevic V; Heino M; Ranki A; Jussila T; Krohn KJ
- Marked activation of the tumour necrosis factor system in AIDS-associated cryptococcosis [letter]
- AIDS. 1996 Oct;10(12):1436-8. Unique Identifier : AIDSLINE MED/97057740
- Mastroianni CM; Lichtner M; Mengoni F; Santopadre P; Vullo V; Delia S
- Susceptibility of peripheral blood mononuclear cells from gorillas, orangutans and baboons to diverse HIV isolates [letter]
- AIDS. 1996 Oct;10(12):1438-40. Unique Identifier : AIDSLINE MED/97057741
- Locher CP; Blackbourn DJ; Castro BA; Brasky KM; Levy JA
- Cytotoxic T-lymphocyte response induced by a V3 loop synthetic peptide from an African HIV-1 isolate is cross-reactive against HIV-1 strains from North America/Europe region [letter]
- AIDS. 1996 Oct;10(12):1440-1. Unique Identifier : AIDSLINE MED/97057742
- Casement KS; Arlinghaus KB; Sastry KJ
- Identification of a novel human leukocyte antigen A26-restricted epitope in a conserved region of Gag [letter]
- AIDS. 1996 Oct;10(12):1441-3. Unique Identifier : AIDSLINE MED/97057743
- Goulder P; Conlon C; Mclntyre K; McMichael A
- Cerebral proton magnetic resonance spectroscopy in cytomegalovirus encephalitis and HIV leucoencephalopathy/encephalitis [letter]
- AIDS. 1996 Oct;10(12):1443-4. Unique Identifier : AIDSLINE MED/97057744
- Wilkinson ID; Miller RF; Paley MN; Miszkiel KA; Kendall BE; Hall-Craggs MA; Harrison MJ
- CD4+ lymphocyte count variations in HIV-negative subjects treated with zidovudine [letter]
- AIDS. 1996 Oct;10(12):1444-5. Unique Identifier : AIDSLINE MED/97057745
- Milazzo L; Vaira LM; Cremoni L
- The influence of intravenous drug use and HIV infection in the transmission of tuberculosis [letter; comment]
- AIDS. 1996 Oct;10(12):1445-6. Unique Identifier : AIDSLINE MED/97057746
- Collazos J; Gonzalez-Bricio A
- The influence of intravenous drug use and HIV infection in the transmission of tuberculosis [letter]
- AIDS. 1996 Oct;10(12):1446-7. Unique Identifier : AIDSLINE MED/97057747
- Cayla JA; Garcia de Olalla P; Galdos-Tanguis H; Vidal R; Lopez-Colomes JL; Gatell JM; Jansa JM
- HIV among drug users in regional towns near the initial focus of the Dutch epidemic [letter]
- AIDS. 1996 Oct;10(12):1448-9. Unique Identifier : AIDSLINE MED/97057748
- Wiessing LG; Houweling H; Spruit IP; Korf DJ; van Duynhoven YT; Fennema JS; Borgdorff MW
- Job's syndrome associated with HIV infection improved with immune globulin therapy [letter]
- AIDS. 1996 Oct;10(12):1449-50. Unique Identifier : AIDSLINE MED/97057749
- Domingo P; Ris J; Puig M; Lopez-Contreras J
- Plasma levels of soluble CD30, tumour necrosis factor (TNF)-alpha and TNF receptors during primary HIV-1 infection: correlation with HIV-1 RNA and the clinical outcome.
- AIDS. 1996 Nov;10(13):F45-50. Unique Identifier : AIDSLINE MED/97085691
- Rizzardi GP; Barcellini W; Tambussi G; Lillo F; Malnati M; Perrin L; Lazzarin A; Institute of Internal Medicine, Infectious Diseases and; Immunopathology, University of Milan, Italy.
- OBJECTIVES: The immunological and virological events associated with primary HIV-1 infection have a major impact on the course of HIV-1 disease, and the identification of early predictors during primary HIV infection is critical for the therapeutic strategy. DESIGN AND METHODS: Eighteen consecutive patients with prima
- Testing for HIV at home: what are the issues? [editorial] [see comments]
- AIDS. 1996 Nov;10(13):1455-65. Unique Identifier : AIDSLINE MED/97085692
- Schopper D; Vercauteren G
- Identification of cell subsets expressing intracytoplasmic cytokines within HIV-1-infected lymph nodes.
- AIDS. 1996 Nov;10(13):1467-75. Unique Identifier : AIDSLINE MED/97085693
- Gray CM; Morris L; Murray J; Keeton J; Shalekoff S; Lyons SF; Sonnenberg P; Martin DJ; Medical Research Council AIDS Virus Research Unit, National Institute; for Virology, Johannesburg, South Africa.
- OBJECTIVE: To describe the endogenous cytokine profile of HIV-1-infected lymph nodes (LN) and to identify the phenotype of individual cells expressing intracytoplasmic cytokines. DESIGN AND METHODS: Whole LN biopsies were collected from three HIV-seronegative controls and four HIV-1-positive individuals with persisten
- CD4+ memory T cells are the predominant population of HIV-1-infected lymphocytes in neonates and children.
- AIDS. 1996 Nov;10(13):1477-84. Unique Identifier : AIDSLINE MED/97085694
- Sleasman JW; Aleixo LF; Morton A; Skoda-Smith S; Goodenow MM; Department of Pediatrics, University of Florida College of Medicine,; Gainesville 32610-0296, USA.
- BACKGROUND: CD4+ memory T cells express CD45RO and are the principal viral reservoir in HIV-infected adults. In infants and children, CD45RO T cells comprise the minority of the CD4+ T-cell population. The majority of blood CD4+ T cells are naive, expressing CD45RA. OBJECTIVE: To determine the developmental stage at w
- Phylogenetic analysis of the env gene of HIV-1 isolates taking into account individual nucleotide substitution rates.
- AIDS. 1996 Nov;10(13):1485-94. Unique Identifier : AIDSLINE MED/97085695
- Van de Peer Y; Janssens W; Heyndrickx L; Fransen K; van der Groen G; De Wachter R; Department of Biochemistry, University of Antwerp, Belgium.
- OBJECTIVE: To estimate the relative substitution rate of the individual positions in an alignment of HIV-1 env sequences coding for areas V3, V4, V5, and the beginning of gp41, and to study phylogenetic relationships between HIV-1 strains taking into account these substitution rate estimates. DESIGN: Phylogenetic comp
- Monokine products as predictors of AIDS dementia.
- AIDS. 1996 Nov;10(13):1495-500. Unique Identifier : AIDSLINE MED/97085696
- Pulliam L; Clarke JA; McGrath MS; Moore D; McGuire D; Department of Laboratory Medicine, Veterans Affairs Medical Center,; San Francisco, CA 94121, USA.
- OBJECTIVE: To determine whether or not soluble factors produced by peripheral blood mononuclear cells (PBMC) can predict AIDS dementia . DESIGN AND METHODS: PBMC were isolated from individuals with and without AIDS dementia complex (ADC) to determine if the levels of cytokines tumou
- Effects of thalidomide on HIV-associated wasting syndrome: a randomized, double-blind, placebo-controlled clinical trial.
- AIDS. 1996 Nov;10(13):1501-7. Unique Identifier : AIDSLINE MED/97085697
- Reyes-Teran G; Sierra-Madero JG; Martinez del Cerro V; Arroyo-Figueroa H; Pasquetti A; Calva JJ; Ruiz-Palacios GM; Department of Infectious Diseases, Instituto Nacional de la Nutricion; Salvador Zubiran, Tlalpan, Mexico, D.F., Mexico.
- OBJECTIVE: To evaluate the efficacy of thalidomide in treating wasting syndrome in patients with advanced HIV disease, and to assess the effects of thalidomide on circulating CD4+ T cells, and on HIV viral burden in peripheral blood mononuclear cells PBMC). DESIGN: Randomized, double-blind placebo-controlled clinical
- Impaired absorption of zidovudine in patients with AIDS-related small intestinal disease.
- AIDS. 1996 Nov;10(13):1509-14. Unique Identifier : AIDSLINE MED/97085698
- Kapembwa MS; Fleming SC; Orr M; Wells C; Bland M; Back D; Griffin GE; Department of Genitourinary Medicine, Imperial College of Science, St; Mary's Hospital Medical School, London, UK.
- OBJECTIVES: To investigate the effect of small intestinal disease SID) on the absorption of zidovudine (ZDV) in patients with AIDS. METHODS: Fourteen fasted homosexual men with AIDS received a single oral dose of ZDV (5 mg/kg). Nine subjects had clinical evidence of intestinal disease (chronic diarrhoea with wasting)
- Cytomegalovirus retinitis in AIDS patients: influence of cytomegaloviral load on response to ganciclovir, time to recurrence and survival.
- AIDS. 1996 Nov;10(13):1515-20. Unique Identifier : AIDSLINE MED/97085699
- Bowen EF; Wilson P; Cope A; Sabin C; Griffiths P; Davey C; Johnson M; Emery V; Department of Virology, Royal Free Hospital and School of Medicine,; London, UK.
- OBJECTIVES: Despite life-long maintenance therapy, cytomegalovirus ( CMV ) retinitis frequently progresses in patients with AIDS. Virological markers that could clarify pathogenesis and identify risk factors for progression are
- Predictive value of Toxoplasma gondii antibody titres on the occurrence of toxoplasmic encephalitis in HIV-infected patients. ANRS 005/ACTG 154 Trial Group.
- AIDS. 1996 Nov;10(13):1521-7. Unique Identifier : AIDSLINE MED/97085700
- Derouin F; Leport C; Pueyo S; Morlat P; Letrillart B; Chene G; Ecobichon JL; Luft B; Aubertin J; Hafner R; Vilde JL; Salamon R; Laboratory of Parasitology, Saint-Louis Hospital, Paris, France.
- OBJECTIVE: To study the predictive value of anti-Toxoplasma gondii antibody titres for the occurrence of toxoplasmic encephalitis (TE) in HIV-infected patients. METHODS: Data from the placebo arm of a trial of primary prophylaxis for TE (ANRS 005/ACTG 154) were analysed. Patients included had CD4+ cell counts
- The metabolic response to opportunistic infections in AIDS.
- AIDS. 1996 Nov;10(13):1529-33. Unique Identifier : AIDSLINE MED/97085701
- Sharpstone DR; Ross HM; Gazzard BG; Department of HIV/Genito-Urinary Medicine, Chelsea and Westminster; Hospital, London, UK.
- OBJECTIVE: The metabolic response to AIDS-defining opportunistic infections was examined to provide a logical basis for the management of associated weight loss. DESIGN: A prospective study of metabolism in AIDS. SETTING: HIV outpatients department and wards at the Chelsea and Westminster Hospital, London. PATIENTS:
- Immunological activation markers in the serum of African and European HIV-seropositive and seronegative individuals.
- AIDS. 1996 Nov;10(13):1535-42. Unique Identifier : AIDSLINE MED/97085702
- Rizzardini G; Piconi S; Ruzzante S; Fusi ML; Lukwiya M; Declich S; Tamburini M; Villa ML; Fabiani M; Milazzo F; Clerici M; First Division of Infectious Disease, University of Milan, Luigi Sacco; Hospital, Italy.
- OBJECTIVE: The concentration of type 1 and type 2 cytokines and fibroblast-associated apoptosis-1 soluble receptor (sAPO-1/Fas) was analysed in the sera of Ugandan and Italian HIV-1-seropositive and seronegative individuals. The data were compared to determine whether the immunological status of these groups was diffe
- Chlamydia pneumoniae seroprevalence among HIV-1-infected and uninfected people with known HIV risk factor.
- AIDS. 1996 Nov;10(13):1543-7. Unique Identifier : AIDSLINE MED/97085703
- Viscott Comandini U; Massetti AP; Marchese R; Zaccarelli M; Vullo V; Delia S; Department of Infectious and Tropical Diseases, La Sapienza; University, Rome, Italy.
- OBJECTIVE: To evaluate the prevalence of Chlamydia pneumoniae antibodies in an Italian population of HIV-infected and uninfected individuals in relation to the presence of HIV risk factors. DESIGN AND METHODS: A prospective evaluation of C. pneumoniae microimmunofluorescence immunoglobulin (Ig) G and IgM titres, in re
- Reasons for HIV antibody test refusal in a heterosexual sexually transmitted disease clinic population.
- AIDS. 1996 Nov;10(13):1549-53. Unique Identifier : AIDSLINE MED/97085704
- Simon PA; Weber M; Ford WL; Cheng F; Kerndt PR; HIV Epidemiology Program, Los Angeles County Department of Health; Services, California 90005, USA.
- OBJECTIVE: To evaluate acceptance of confidential HIV antibody testing and reasons for test refusal among heterosexual clients of Los Angeles County sexually transmitted disease (STD) clinics. METHODS: From January 1993 through June 1994, all blood specimens routinely collected for syphilis serology were tested blindl
- The feasibility of HIV-1 vaccine efficacy trials among gay/bisexual men in New York City: Project ACHIEVE. AIDS Community Health Initiative Enroute to the Vaccine EFfort.
- AIDS. 1996 Nov;10(13):1555-61. Unique Identifier : AIDSLINE MED/97085705
- Koblin BA; Taylor PE; Avrett S; Stevens CE; Wolf Szmuness Laboratory of Epidemiology, New York Blood Center, New; York 10021, USA.
- OBJECTIVE: Candidate populations for HIV-1 vaccine efficacy trials need to be at high risk of infection, adhere to study protocols and be willing to participate. The goal of Project ACHIEVE is to collect baseline data needed in order to prepare for vaccine efficacy trials among gay/bisexual men in New York City. DESIG
- Spectrum of disease in Africans with AIDS in London.
- AIDS. 1996 Nov;10(13):1563-9. Unique Identifier : AIDSLINE MED/97085706
- Del Amo J; Petruckevitch A; Phillips AN; Johnson AM; Stephenson JM; Desmond N; Hanscheid T; Low N; Newell A; Obasi A; Paine K; Pym A; Theodore CM; De Cock KM; Department of STD, Mortimer Market Centre, London, UK.
- OBJECTIVE: To compare the spectrum of disease, severity of immune deficiency and chemoprophylaxis prescribed in HIV-infected African and non-African patients in London. DESIGN: Retrospective review of case notes of all HIV-infected Africans and a comparison group of non-Africans attending 11 specialist HIV/AIDS Units
- United Kingdom AIDS survival in adults.
- AIDS. 1996 Nov;10(13):1571-8. Unique Identifier : AIDSLINE MED/97085707
- Rogers PA; Gore SM; Whitmore-Overton SE; Allardice GM; Swan AV; Noone A; Public Health Laboratory Service (PHLS) Statistics Unit, Communicable; Disease Surveillance Centre, London, UK.
- OBJECTIVE: To examine the impact of age, year and region of AIDS diagnosis on early (up to 12 months) and late survival of AIDS patients in different exposure categories; to describe the hazard pattern from 12 months after AIDS diagnosis. PATIENTS: A total of 4577 UK adult AIDS diagnoses to the end of 1991 in men who
- Distribution of HIV-1 subtypes seen in an AIDS clinic in Sao Paulo City, Brazil.
- AIDS. 1996 Nov;10(13):1579-84. Unique Identifier : AIDSLINE MED/97085708
- Sabino EC; Diaz RS; Brigido LF; Learn GH; Mullins JI; Reingold AL; Duarte AJ; Mayer A; Busch MP; Instituto Adolfo Lutz, Sao Paulo, Brazil.
- OBJECTIVE: To determine the distribution of HIV-1 subtypes in Sao Paulo, Brazil . METHODS: Samples were obtained from 80 consecutive HIV-1-infected individuals attending the Immunodeficiency Clinic at the University of Sao Paulo in 1993. Peripheral blood mononuclear cells (PBMC) wer
- Age of wife as a major determinant of male-to-female transmission of HIV-2 infection: a community study from rural West Africa.
- AIDS. 1996 Nov;10(13):1585-90. Unique Identifier : AIDSLINE MED/97085709
- Aaby P; Ariyoshi K; Buckner M; Jensen H; Berry N; Wilkins A; Richard D; Larsen O; Dias F; Melbye M; Whittle H; Department of Epidemiology Research, Danish Epidemiology Science; Centre, Statens Seruminstitut, Copenhagen, Denmark.
- OBJECTIVE: To examine whether proviral load is important for transmission between spouses, since we have previously found that the proviral load of HIV-2 predicts the severity of infection. DESIGN: Proviral load was examined in 121 HIV-2-infected adults in a rural area of Guinea-Bissa
- HIV therapy in the real world [editorial]
- AIDS. 1996 Nov;10(13):1591-3. Unique Identifier : AIDSLINE MED/97085710
- Selwyn PA
- The sex ratio of AIDS-associated Kaposi's sarcoma does not provide evidence that sex hormones play a role in pathogenesis [letter]
- AIDS. 1996 Nov;10(13):1595-6. Unique Identifier : AIDSLINE MED/97085711
- Grulich AE; Kaldor JM
- Detection of Kaposi's sarcoma herpesvirus DNA in semen of homosexual men with Kaposi's sarcoma [letter]
- AIDS. 1996 Nov;10(13):1596-8. Unique Identifier : AIDSLINE MED/97085712
- Gupta P; Singh MK; Rinaldo C; Ding M; Farzadegan H; Saah A; Hoover D; Moore P; Kingsley L
- Syncytium-inducing HIV-1 variants replicate equally well in all types of T-helper cell clones [letter]
- AIDS. 1996 Nov;10(13):1598-600. Unique Identifier : AIDSLINE MED/97085713
- Meyaard L; Fouchier RA; Brouwer M; Hovenkamp E; Miedema F
- Better prediction of vertical HIV-1 transmission from maternal blood at delivery compared with cord blood samples [letter]
- AIDS. 1996 Nov;10(13):1600-1. Unique Identifier : AIDSLINE MED/97085714
- Zollner B; Feucht HH; Mattner UM; Helling-Giese G; Baumgartner EM; Laufs R
- Temporal trends of the natural history of HIV-1 infection following seroconversion between 1984 and 1993 [letter]
- AIDS. 1996 Nov;10(13):1601-2. Unique Identifier : AIDSLINE MED/97085715
- Keet IP; Veugelers PJ; Koot M; de Weerd MH; Roos MT; Miedema F; de Wolf F; Goudsmit J; Coutinho RA
- Secondary Pneumocystis carinii pneumonia prophylaxis with trimethoprim-sulphamethoxazole does not prevent bacterial pneumonia in HIV-infected persons [letter]
- AIDS. 1996 Nov;10(13):1603-4. Unique Identifier : AIDSLINE MED/97085716
- Tumbarello M; Tacconelli E; Cauda R; Ortona L
- AIDS-related varicella zoster meningoencephalitis and radicular pain without cutaneous eruption [letter]
- AIDS. 1996 Nov;10(13):1604-6. Unique Identifier : AIDSLINE MED/97085717
- Debat Zoguereh D; Saadoun R; Zandotti C; Cawston P; Moreau J
- Thrombocytopenia and AIDS: possible direct role of HIV [letter]
- AIDS. 1996 Nov;10(13):1606-8. Unique Identifier : AIDSLINE MED/97085718
- Borgia G; Reynaud L; Cicciarello S; Tallarino A; Fratellanza G; Lambiase A; Nasti G; Simonelli C; Foggia M; Tirelli U; Piazza M
- Compulsory HIV testing: medical students' views [letter]
- AIDS. 1996 Nov;10(13):1608-9. Unique Identifier : AIDSLINE MED/97085719
- Williams S; Elford J; Cockcroft A
- Nosocomial outbreak of tuberculosis in an outpatient HIV treatment room [letter; comment]
- AIDS. 1996 Nov;10(13):1609. Unique Identifier : AIDSLINE MED/97085720
- Singh G
- Perspective: research highlights at the Dana-Farber Cancer Institute Center for AIDS Research (CFAR).
- AIDS Res Hum Retroviruses. 1996 Nov 1;12(16):1499-502. Unique Identifier : AIDSLINE MED/97068246
- Sodroski J; Dana-Farber Cancer Institute, Department of Pathology, Harvard Medical; School, Boston, Massachusetts, USA.
- V3 loop sequence analysis of seven HIV type 1 group O isolates phenotyped in peripheral blood mononuclear cells and MT-2 cells.
- AIDS Res Hum Retroviruses. 1996 Nov 1;12(16):1503-7. Unique Identifier : AIDSLINE MED/97068247
- De Jong J; Simon F; Van der Groen G; Baan E; Saragosti S; Brun-Vezinet F; Goudsmit J; Department of Human Retrovirology, Academic Medical Centre, Amsterdam,; The Netherlands.
- HIV-1-infected individuals from which syncytium-inducing (SI) viruses are isolated most often progress more rapidly to AIDS than individuals carrying only non-syncytium-inducing (NSI) viruses. The syncytium-inducing capacity of virus isolates is commonly determined in conjunction to replication in MT-2 cells. Comparis
- Neutralization of HIV type 1 infectivity by serum antibodies from a subset of autoimmune patients with mixed connective tissue disease.
- AIDS Res Hum Retroviruses. 1996 Nov 1;12(16):1509-17. Unique Identifier : AIDSLINE MED/97068248
- Douvas A; Takehana Y; Ehresmann G; Chernyovskiy T; Daar ES; Department of Medicine, University of Southern California School of; Medicine, Los Angeles 90033, USA.
- Mixed connective tissue disease (MCTD) is a rheumatic disorder with clinical similarities to HIV-1 infection, and with characteristic autoimmune anti-RNP antibodies specific for the U1 snRNP splicing complex. Anti-RNP antibodies cross-react with the HIV-1 surface, owing to multiple homologies between the gp120/41 enve
- Activation of the HIV type 1 long terminal repeat by X-irradiation involves two main Re1/NF-kappa B DNA-binding complexes.
- AIDS Res Hum Retroviruses. 1996 Nov 1;12(16):1519-27. Unique Identifier : AIDSLINE MED/97068249
- Faure E; Lecine P; Imbert J; Champion S; Institut de Chimie Biologique, Universite de Provence, Marscelle,; France.
- Transcription of human immunodeficiency virus type 1 (HIV-1) is regulated by multiple cis-acting regulatory elements located in the viral long terminal repeats (LTRs). HIV-1 LTR enhancer is activated by a variety of heterologous viral, chemical, and physical agents. Studies have demonstrated that irradiation by X-rays
- Effect of HIV type 1 Tat protein on butyric acid-induced differentiation in a hematopoietic progenitor cell line.
- AIDS Res Hum Retroviruses. 1996 Nov 1;12(16):1529-36. Unique Identifier : AIDSLINE MED/97068250
- Mondal D; Agrawal KC; Department of Pharmacology, Tulane University School of Medicine, New; Orleans, Louisiana 70112, USA.
- The trans-activator protein (Tat) of HIV-1 plays an important role in viral pathogenesis. Since Tat has been shown to alter expression of a number of host cellular genes, we have investigated the role of Tat in modulating gene expression and differentiation in hematopoietic progenitor cells. Tat protein was introduced
- Glutathione inhibits HIV replication by acting at late stages of the virus life cycle.
- AIDS Res Hum Retroviruses. 1996 Nov 1;12(16):1537-41. Unique Identifier : AIDSLINE MED/97068251
- Palamara AT; Perno CF; Aquaro S; Bue MC; Dini L; Garaci E; Department of Experimental Medicine and Biochemical Sciences,; University of Rome, Italy.
- We investigated the effect of glutathione on the replication of human immunodeficiency virus (HIV) in chronically infected macrophages, a known reservoir of the virus in the body. We found that exogenous GSH strongly suppresses the production of p24gag protein as well as the virus infectivity. This is related to a dra
- A high frequency of defective vif genes in peripheral blood mononuclear cells from HIV type 1-infected individuals.
- AIDS Res Hum Retroviruses. 1996 Nov 1;12(16):1543-9. Unique Identifier : AIDSLINE MED/97068252
- Tominaga K; Kato S; Negishi M; Takano T; Department of Microbiology, Keio University School of Medicine, Tokyo,; Japan.
- We studied the heterogeneity and intactness of the vif gene in six HIV-1-infected individuals at various clinical stages. The proviral vif sequences in peripheral blood mononuclear cells were amplified by PCR, followed by cloning and sequencing of 45 vif clones. The intraindividual diversity of the vif genes ranged fr
- HIV type 1 RNA expression in bone marrows of patients with a spectrum of disease.
- AIDS Res Hum Retroviruses. 1996 Nov 1;12(16):1551-8. Unique Identifier : AIDSLINE MED/97068253
- Weiser B; Burger H; Campbell P; Donelan S; Mladenovic J; Wadsworth Center, New York State Department of Health and Albany; Medical College, New York 12201-2002, USA.
- HIV-1-infected individuals at various stages of disease harbor virus in their lymphoid organs, which serve as reservoirs of viral replication throughout the course of infection. Hematologic abnormalities are extremely common in HIV-1-infected individuals and occur at all stages of disease. To determine if the bone mar
- Early impairment of systolic and diastolic function in asymptomatic HIV-positive patients: a multicenter echocardiographic and echo-Doppler study. The Gruppo Italiano Per lo Studio Cardiologico dei Pazienti Affetti da AIDS.
- AIDS Res Hum Retroviruses. 1996 Nov 1;12(16):1559-63. Unique Identifier : AIDSLINE MED/97068254
- Barbaro G; Barbarini G; Di Lorenzo G; Department of Emergency Medicine, University La Sapienza, Rome, Italy.
- Human immunodeficiency virus (HIV) possesses an intrinsic cardiopathogenic action that may be detected even in the early stages of HIV disease. To assess an early impairment of systolic and diastolic function in asymptomatic HIV-positive patients CD4+ > or = 600/mm3), we performed a multicenter echocardiographic and e
- Workshop on perinatally acquired human immunodeficiency virus infection in long-term surviving children: a collaborative study of factors contributing to slow disease progression. The Long-Term Survivor Project.
- AIDS Res Hum Retroviruses. 1996 Nov 1;12(16):1565-70. Unique Identifier : AIDSLINE MED/97068255
- Martin N; Koup R; Kaslow R; Coffin J; Ammann A; Pediatric AIDS Foundation, Novato, California 94949, USA.
- Characterization of V3 loop of HIV type 1 spreading rapidly among injection drug users of Manipur, India: a molecular epidemiological perspective.
- AIDS Res Hum Retroviruses. 1996 Nov 1;12(16):1571-3. Unique Identifier : AIDSLINE MED/97068256
- Panda S; Wang G; Sarkar S; Perez CM; Chakraborty S; Agarwal A; Dorman K; Sarkar K; Detels R; Kaplan AH; Indian Council of Medical Research (ICMR) Unit for Research on AIDS,; Salt Lake, Calcutta, India.
- Genetic and phylogenetic analysis of HIV type 1 env subtypes in Ghana, west Africa.
- AIDS Res Hum Retroviruses. 1996 Nov 1;12(16):1575-8. Unique Identifier : AIDSLINE MED/97068257
- Ishikawa K; Janssens W; Brandful J; Heyndrickx L; Takebe Y; Ampofo W; Sata T; Yamazaki S; Osei-Kwasi M; Yamamoto N; Koyanagi Y; Van der Groen G; Kurata T; Laboratory of AIDS Pathology, National Institute of Health, Tokyo,; Japan.
- Unraveling the function of HIV type 1 Nef.
- AIDS Res Hum Retroviruses. 1996 Nov 20;12(17):1579-82. Unique Identifier : AIDSLINE MED/97102919
- Geleziunas R; Miller MD; Greene WC; Gladstone Institute of Virology and Immunology, University of; California, San Francisco 94141, USA.
- Syndrome of recurrent transient neurological deficits in patients with HIV infection [letter]
- AIDS Res Hum Retroviruses. 1996 Nov 20;12(17):1583. Unique Identifier : AIDSLINE MED/97102920
- Manfredi R; Azzimondi G; Rinaldi R; Tonon C; Mastroianni A; Coronado OV; D'Alessandro R; Chiodo F
- In vitro characterization of HIV type 1 biological clones from asymptomatic and symptomatic pediatric patients.
- AIDS Res Hum Retroviruses. 1996 Nov 20;12(17):1585-93. Unique Identifier : AIDSLINE MED/97102921
- Forte SE; Sullivan JL; Somasundaran M; Department of Pediatrics, University of Massachusetts Medical Center,; Worcester 01605, USA.
- To investigate the mechanisms of HIV-1 cytopathogenicity, functional biological HIV-1 clones were isolated from two infected children with high viral loads in vivo. Clone HC4 was isolated from a symptomatic child and clone GC6 8-4 was isolated from an asymptomatic child. These clones were characterized for their abili
- Molecular epidemiology and MT-2 cell tropism of Russian HIV type 1 variant.
- AIDS Res Hum Retroviruses. 1996 Nov 20;12(17):1595-603. Unique Identifier : AIDSLINE MED/97102922
- Leitner T; Korovina G; Marquina S; Smolskaya T; Albert J; Department of Clinical Virology, Swedish Institute for Infectious; Disease Control, Karolinska Institute, Stockholm, Sweden.
- Twenty-two HIV-1-infected Russian individuals were studied to gain better insight on the genetic and biological characteristics of HIV-1 variants present in Russia. The V3 domain of the HIV-1 envelope was directly sequenced from cultured peripheral blood mononuclear cells (PBMCs). Phylogenetic analyses were used to de
- Lentiviral genomes with G-to-A hypermutation may result from Taq polymerase errors during polymerase chain reaction.
- AIDS Res Hum Retroviruses. 1996 Nov 20;12(17):1605-13. Unique Identifier : AIDSLINE MED/97102923
- Overbaugh J; Jackson SM; Papenhausen MD; Rudensey LM; Department of Microbiology, University of Washington, Seattle 98195,; USA.
- Retroviral genomes with a high frequency of G-to-A mutations are thought to originate during reverse transcription. Here we show that bursts of G-to-A mutation may also occur during DNA synthesis by Taq polymerase on a simian immunodeficiency proviral template. These G-to-A changes tend to occur at GpA and, to a lesse
- Alteration of CD44 expression in HIV type 1-infected T cell lines.
- AIDS Res Hum Retroviruses. 1996 Nov 20;12(17):1615-22. Unique Identifier : AIDSLINE MED/97102924
- Giordanengo V; Limouse M; Doglio A; Lesimple J; Lefebvre JC; Laboratoire de Virologie, Faculte de Medecine, Nice, France.
- CD44 is known to interfere in HIV replication and to participate in many physiological processes such as lymphocyte binding to high endothelial venules of lymphoid tissue, lymph nodes, and mucosal endothelium. The T cell lines MOLT-4 and CEM, and CEM subclones were infected with the HIV-1 LAI strain and monitored for
- Twenty-five years of HTLV type II follow-up with a possible case of tropical spastic paraparesis in the Kayapo, a Brazilian Indian tribe.
- AIDS Res Hum Retroviruses. 1996 Nov 20;12(17):1623-7. Unique Identifier : AIDSLINE MED/97102925
- Black FL; Biggar RJ; Lal RB; Gabbai AA; Filho JP; Department of Public Health, Yale University, School of Medicine, New; Haven, Connecticut 06520-8034, USA.
- A longitudinal study, spanning 25 years and great demographic and cultural change, found a persistently high prevalence of human T-lymphotropic virus type II (HTLV-II) in the Xikrin Kayapo Indians of Brazil . More than 10% of the children continue to develop immune reactions to the
- Infection of human T lymphoid cells by human herpesvirus 6 is blocked by two unrelated protein tyrosine kinase inhibitors, biochanin A and herbimycin.
- AIDS Res Hum Retroviruses. 1996 Nov 20;12(17):1629-34. Unique Identifier : AIDSLINE MED/97102926
- Cirone M; Zompetta C; Tarasi D; Frati L; Faggioni A; Dipartimento di Medicina Sperimentale e Patologia, Universita degli; Studi La Sapienza, Rome, Italy.
- Human herpesvirus 6 is a T lymphotropic herpesvirus that causes exanthem subitum in infants and is considered a potential cofactor in AIDS etiopathogenesis and progression owing to its in vivo and in vitro interactions with human immunodeficiency virus. We report that no differences in phosphorylation on tyrosine resi
- Intracellular glutathione as a possible direct blocker of HIV type 1 reverse transcription.
- AIDS Res Hum Retroviruses. 1996 Nov 20;12(17):1635-8. Unique Identifier : AIDSLINE MED/97102927
- Kameoka M; Okada Y; Tobiume M; Kimura T; Ikuta K; Section of Serology, Hokkaido University, Sapporo, Japan.
- In AIDS patients, chronic inflammation and elevated levels of cytokines seem to be associated with reduced levels of glutathione (GSH). GSH has been proposed to inhibit the activation of NF-kB, which results in the inhibition of HIV-1 replication. Here, we show the evidence that GSH and N-acetylcysteine, but not L-cys
- Elevated hepatic gamma-glutamylcysteine synthetase activity and abnormal sulfate levels in liver and muscle tissue may explain abnormal cysteine and glutathione levels in SIV-infected rhesus macaques.
- AIDS Res Hum Retroviruses. 1996 Nov 20;12(17):1639-41. Unique Identifier : AIDSLINE MED/97102928
- Gross A; Hack V; Stahl-Hennig C; Droge W; Department of Immunochemistry, Deutsches Krebsforschungszentrum,; Heidelberg, Germany.
- To establish whether the low cysteine and glutathione levels in HIV-infected patients and SIV-infected rhesus macaques may be consequences of an abnormal cysteine catabolism, we analyzed sulfate and glutathione levels in macaques. Muscle tissue (m. vastus lateralis and m. gastrocnemius) of SIV-infected macaques n = 25
- Genetic and biological analysis of variants derived from the cerebrospinal fluid of HIV type 1 subtype B- and D- infected patients with and without AIDS dementia complex.
- AIDS Res Hum Retroviruses. 1996 Nov 20;12(17):1643-5. Unique Identifier : AIDSLINE MED/97102929
- Brengel-Pesce K; Morand P; Innocenti-Francillard P; Chanzy B; Bourgeat MJ; Leclercq P; Micoud M; Seigneurin JM; Laboratoire de Virologie-RAHP, Faculte de Medicine de Grenoble, La; Tronche, France.
- Env gene characterization of the first HIV type 1 group O Spanish isolate.
- AIDS Res Hum Retroviruses. 1996 Nov 20;12(17):1647-9. Unique Identifier : AIDSLINE MED/97102930
- Mas A; Quinones-Mateu E; Soriano V; Domingo E; Servicio de Enfermedades Infecciosas, Instituto de Salud Carlos III,; Madrid, Spain.
- Coexistence of subtypes B, F, and as B/F env recombinant of HIV type 1 in Buenos Aires Argentina.
- AIDS Res Hum Retroviruses. 1996 Nov 20;12(17):1651-4. Unique Identifier : AIDSLINE MED/97102931
- Marquina S; Leitner T; Rabinovich RD; Benetucci J; Libonatti O; Albert J; Department of Microbiology, University of Buenos Aires, School of; Medicine, Argentina.
- HIV type 1 subtypes in Malaysia include B, C, and E.
- AIDS Res Hum Retroviruses. 1996 Nov 20;12(17):1655-7. Unique Identifier : AIDSLINE MED/97102932
- Brown TM; Robbins KE; Sinniah M; Saraswathy TS; Lee V; Hooi LS; Vijayamalar B; Luo CC; Ou CY; Rapier J; Schochetman G; Kalish ML; Division of AIDS/STD/TB/Laboratory Research, Centers for Disease; Control and Prevention, Atlanta, Georgia 30333, USA.
- HIV/AIDS: the global epidemic, December 1996.
- Wkly Epidemiol Rec. 1997 Jan 24;72(4):17-21. Unique Identifier : AIDSLINE MED/97172702
- Cryptococcosis.
- Adv Pharmacol. 1997;37:215-51. Unique Identifier : AIDSLINE MED/97046181
- Aberg JA; Powderly WG; AIDS Clinical Trials Unit, Washington University School of Medicine,; St. Louis, Missouri 63108, USA.
- Structural RNA mimetics: N3'-->P5' phosphoramidate DNA analogs of HIV-1 RRE and TAR RNA form A-type helices that bind specifically to Rev and Tat-related peptides.
- Biochemistry. 1997 Jan 21;36(3):650-9. Unique Identifier : AIDSLINE MED/97164918
- Rigl CT; Lloyd DH; Tsou DS; Gryaznov SM; Wilson WD; Department of Chemistry, Georgia State University, Atlanta 30303, USA.
- An attractive strategy for the development of anti-retroviral drugs is the exploration of compounds that mimic RNA control regions of the viral genome and act as decoys to sequester viral gene regulatory proteins. Decoys consisting of RNA, however, are chemically unstable and readily degraded by cellular nucleases.
- Squamous intraepithelial lesions among adolescent women infected with human immunodeficiency virus [letter]
- J Adolesc Health. 1996 Oct;19(4):246-7. Unique Identifier : AIDSLINE MED/97052467
- Clark R; Kissinger P; Fuller C; Abdalian SE
- Delivery of STD/HIV preventive services to adolescents by primary care physicians.
- J Adolesc Health. 1996 Oct;19(4):249-57. Unique Identifier : AIDSLINE MED/97052468
- Millstein SG; Igra V; Gans J; School of Medicine, University of California, San Francisco 94143 USA.
- PURPOSE: To document the rates of STD/HIV preventive services delivered to adolescents by primary care physicians in California, and to identify variation owing to physician and practice-related factors. METHODS: A stratified random sample of California internists, family physicians, obstetricians-gynecologists, and p
- Sixth and eighth graders and acquired immunodeficiency syndrome: the results of focus group analysis.
- J Adolesc Health. 1996 Oct;19(4):297-302. Unique Identifier : AIDSLINE MED/97052474
- Palmer DA; Boardman B; Bauchner H; Division of General Pediatrics, Boston City Hospital, Boston; University School of Medicine, Massachusetts 02118, USA.
- OBJECTIVE: To determine young adolescents range of factual knowledge and beliefs about human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) among those who have received AIDS education. DESIGN: Focus group analysis. SETTING: Urban middle school. PARTICIPANTS: Two male and two female groups
- Adolescent health in Russia: a view from Moscow and St. Petersburg.
- J Adolesc Health. 1996 Oct;19(4):308-14. Unique Identifier : AIDSLINE MED/97052476
- Blum RW; Blum L; Phillips S; Smith P; Slap G; Department of Pediatrics, University of Minnesota, Minneapolis 55455,; USA.
- PURPOSE: The purpose of this study was to report on the current state of adolescent health in Russia . METHODS: By means of site visits, literature review, discussions with Russian colleagues, and a scientific meeting in Moscow, data were collected on health status of youth, the org
- Tennessee Nurses Association. Resolution. In support of HIV/AIDS preventive vaccine research.
- Tenn Nurse. 1996 Dec;59(6):13, 18. Unique Identifier : AIDSLINE MED/97178208
- HIV/AIDS health worker stress and burnout: introduction and overview [editorial]
- AIDS Care. 1996 Apr;8(2):133-5. Unique Identifier : AIDSLINE MED/97014579
- Miller D; Department of Sexually Transmitted Diseases, University College London; Medical School, London, UK.
- Prediction of grief and HIV/AIDS-related burnout in volunteers.
- AIDS Care. 1996 Apr;8(2):137-43. Unique Identifier : AIDSLINE MED/97014580
- Nesbitt WH; Ross MW; Sunderland RH; Shelp E; Center for Health Promotion Research and Development, School of Public; Health, University of Texas, Houston 77225, USA.
- Burnout in volunteer workers in the HIV/AIDS area results in the loss of dedicated personnel, consequently straining the HIV/AIDS care delivery system. By assessing the predictors of burnout and grief this study describes the role of grief in HIV/AIDS volunteer burnout. Voluntary and anonymous questionnaires were senta
- The relationship between recognition, rewards and burnout in AIDS caring.
- AIDS Care. 1996 Apr;8(2):145-53. Unique Identifier : AIDSLINE MED/97014581
- Bennett L; Ross MW; Sunderland R; Department of Behavioural & Social Sciences in Nursing, The University; of Sydney, Australia.
- The positive psychological and sociological dimensions of AIDS care provision may produce important information to assist burnout prevention. While most studies on stress and burnout in AIDS health care have focused on the negative and difficult aspects of this work, few have considered the notion that the rewards of a
- HIV counsellors' knowledge, attitudes and vulnerabilities to HIV in Lusaka, Zambia, 1994.
- AIDS Care. 1996 Apr;8(2):155-66. Unique Identifier : AIDSLINE MED/97014582
- Baggaley R; Sulwe J; Kelly M; MacMillan MN; Godfrey-Faussett P; Kara Counselling and Training Trust, Lusaka, Zambia.
- The objective of this study was to see how HIV affected counsellors in their personal and professional lives and how they coped. A total of 101 people who were currently working as HIV counsellors were interviewed. Of these, 70 had a relative who had died of HIV, but few had been able to discuss HIV with them. Seventya
- Is there life after work? Experiences of HIV and oncology health staff.
- AIDS Care. 1996 Apr;8(2):167-82. Unique Identifier : AIDSLINE MED/97014583
- Miller D; Gillies P; Department of Sexually Transmitted Diseases, University College London; Medical School, London, UK.
- A cross-sectional interview survey of 103 HIV/AIDS and 100 oncology staff in nine treatment sites in London aimed to identify ways in which work stress affected domestic and social lives of such staff. In all staff one-third of those without long-term emotional relationships stated they felt their work formed a barriea
- Psychological stress in nurses' relationships with HIV-infected patients: the risk of burnout syndrome.
- AIDS Care. 1996 Apr;8(2):183-94. Unique Identifier : AIDSLINE MED/97014584
- Visintini R; Campanini E; Fossati A; Bagnato M; Novella L; Maffei C; Medical Psychology and Psychotherapy Unit, Neuropsychic Science; Department, Istituto Scientifico San Raffaele, Milan, Italy.
- To assess the role played by psychological stress and sociodemographic factors as predictors of burnout in nurses, we administered the AIDS Impact Scale (AIS) and the Maslach Burnout Inventory (MBI) to nurses in the AIDS field. The sample was composed of 410 nurses from 19 departments for the treatment of infectious da
- Burnout, social support and AIDS volunteers.
- AIDS Care. 1996 Apr;8(2):195-206. Unique Identifier : AIDSLINE MED/97014585
- Maslanka H
- Care providers working with people with HIV have shown high levels of burnout (Maslach, 1986) as staff were required to deal with a multi-faceted disease while creating new ways of working with clients. At the same time high burnout levels were also being seen among volunteers who were supplementing the work of paid sa
- Burnout and related factors among HIV/AIDS health care workers.
- AIDS Care. 1996 Apr;8(2):207-21. Unique Identifier : AIDSLINE MED/97014586
- Bellani ML; Furlani F; Gnecchi M; Pezzotta P; Trotti EM; Bellotti GG; Department of Medical Psychology, University of Pavia School of; Medicine at Varese, Regional Psychological AIDS Centre, Varese, Italy.
- A sample of 194 Italian health care-givers working in HIV/AIDS units was assessed to investigate whether there was a correlation between individual variables (socio-demographic and occupational characteristics, personality traits, anxiety, depression, attitudes and emotional reactions) and burnout and job satisfactiona
- AIDS-related beliefs, attitudes and intentions among Malawian students in three secondary schools.
- AIDS Care. 1996 Apr;8(2):223-32. Unique Identifier : AIDSLINE MED/97014587
- Bandawe CR; Foster D; Department of Community Health, College of Medicine, University of; Malawi, Rondebosch, South Africa.
- This preliminary investigation into factors influencing the intention of Malawian secondary school students to engage in low-risk AIDS-related behaviours was based on the Theory of Reasoned Action (Ajzen & Fishbein, 1980). A total of 191 male and female subjects (mean age 19.32) from three secondary schools in Mala
- Research in psychopathology in patients with HIV/AIDS and psychiatric services in Spain.
- AIDS Care. 1996 Apr;8(2):233-9. Unique Identifier : AIDSLINE MED/97014588
- Ayuso Mateos JL; Lastra I; Montanes F; Social Psychiatry Research Unit of Cantabria, University of Cantabria,; Madrid, Spain.
- In this article, we review the research carried out in Spain concerning psychiatric aspects of HIV/AIDS in general, and of suicide and suicidal ideation in particular. The paper presents available information concerning this psychopathology in patients with HIV infection, along with
- Reflections on the 9th International Conference on AIDS Education-- Interventions in Multi-cultural Societies, Israel 25 November-1 December, 1995.
- AIDS Care. 1996 Apr;8(2):241-2. Unique Identifier : AIDSLINE MED/97014589
- Vowles D
- [Aspergillosis and AIDS (editorial)]
- Enferm Infecc Microbiol Clin. 1996 Nov;14(9):517-8. Unique Identifier : AIDSLINE MED/97170442
- Moreno S; Berenguer J
- [Pseudomonas spp. infections in patients with HIV infections]
- Enferm Infecc Microbiol Clin. 1996 Nov;14(9):519-23. Unique Identifier : AIDSLINE MED/97170443
- Payeras A; Riera M; Riera M; Altes J; Homar F; Gil J; Salas A; Villalonga C; Unidad de Enfermedades Infecciosas, Hospital Son Dureta, Palma de; Mallorca.
- BACKGROUND: The aim of this study was to describe the characteristics of the infections by Pseudomonas spp. observed in patients with HIV infection in Spain . METHODS: A retrospective study was performed of the isolations of Pseudomonas spp. in microbiologic samples of patients with
- [Diagnosis of 4 cases of intestinal microsporidiosis in AIDS patients]
- Enferm Infecc Microbiol Clin. 1996 Nov;14(9):533-7. Unique Identifier : AIDSLINE MED/97170446
- Subirats M; Gonzalez-Castelao G; Aguilera O; Moody A; Visvesvara G; Verdejo J; Baquero M; del Aguila C; Servicio de Microbiologia, CIC., Instituto de Salud Carlos III,; Madrid.
- BACKGROUND: Most of the latest clinical and epidemiologic studies indicate that microsporidiosis and above all Enterocytozoon bieneusi cause approximately 7-50% of otherwise unexplained diarrhea in HIV-infected patients. Four cases of intestinal microsporidiosis in AID
- [Colonic tuberculosis as a cause of rectal bleeding in 2 patients with HIV infection]
- Enferm Infecc Microbiol Clin. 1996 Nov;14(9):538-40. Unique Identifier : AIDSLINE MED/97170447
- Pintor E; Piret MV; Velasco M; Barreiro P; Ruiz M; Blanco J; Servicio de Medicina Interna III, Hospital Universitario San Carlos,; Madrid.
- BACKGROUND: Extrapulmonary tuberculosis is a relatively frequent disease in patients with HIV infection. This may be observed coinciding with pulmonary involvement or without diagnostic data of the same. Within extrapulmonary involvement, gastrointestinal involvement is one of the least frequently observed and its dia
- [Oncogenic mechanisms of Epstein-Barr virus]
- Enferm Infecc Microbiol Clin. 1996 Nov;14(9):551-60. Unique Identifier : AIDSLINE MED/97170451
- Herrero JA; Mayo Foundation, Rochester, Minnesota, USA.
- [Is HVH-8 the etiologic agent for Kaposi's sarcoma? (letter; comment)]
- Enferm Infecc Microbiol Clin. 1996 Nov;14(9):569-70. Unique Identifier : AIDSLINE MED/97170455
- Aspiroz MC; Saenz MC
- [Salmonella septic arthritis in a hemophiliac with AIDS: aggressive treatment (letter)]
- Enferm Infecc Microbiol Clin. 1996 Nov;14(9):573-4. Unique Identifier : AIDSLINE MED/97170460
- Ferre R; Martin-Urda A; Vidal F; Richart C
- Specific radioimmunoassays for the measurement of stavudine in human plasma and urine.
- J Pharm Biomed Anal. 1996 Nov;15(2):165-74. Unique Identifier : AIDSLINE MED/97087415
- Kaul S; Stouffer B; Mummaneni V; Turabi N; Mantha S; Jayatilak P; Barbhaiya R; Bristol-Myers Squibb Pharmaceutical Research Institute, Princeton, NJ; 08543, USA.
- Sensitive and specific radioimmunoassays (RIAs) have been developed and validated for the determination of stavudine , a nucleoside analog possessing anti-human immunodeficiency virus HIV) activity, in human plasma and urine. The hemisuccinate of stavu
- Nursing in the urban core [interview by Helen Griffiths]
- Nurs BC. 1996 Nov-Dec;28(5):14-6. Unique Identifier : AIDSLINE MED/97178126
- Brennan E
- [Composition of HIV-1 B-epitopes and heterologous T-cell epitopes. I. Maintenance of antigenic properties of HIV-1 B-epitopes]
- Biokhimiia. 1996 Jul;61(7):1221-9. Unique Identifier : AIDSLINE MED/97000263
- Isaguliants MG; Koshida R; Ruden U; Varen B; Department of Virology, Swedish Institute for Infectious Disease; Control, Stockholm, Sweden.
- Peptides were synthesized combining an immunodominant B-cell epitope from gp41 of HIV-1 with heterogenous T-cell epitopes from tetanus toxoid or hepatitis B core antigen with no spacer bridge between epitopes. The antigenic properties of the B-cell epitope within the composites were evaluated. The majority of the rabb
- [Composition of HIV-1 B-epitopes and heterologous T-cell epitopes. II. Combined analysis of immunogenicity of composite peptides in rabbits]
- Biokhimiia. 1996 Jul;61(7):1230-40. Unique Identifier : AIDSLINE MED/97000264
- Isaruliants MG; Ruden U; Wahren B; Department of Virology, Swedish Institute for Infectious Disease; Control, Stockholm, Sweden.
- Rabbits were immunized with a mixture of linear cojoined peptides composites) combining an immunodominant B-cell epitope from gp41 of HIV-1 (amino acids 593-604) and a heterogeneous T-cell epitope from tetanus toxoid or hepatitis B core antigen. HIV-1 B-epitope in the context of the composites induced HIV-1 specific a
- Drug interactions in patients infected with human immunodeficiency virus.
- Clin Infect Dis. 1996 Oct;23(4):685-93. Unique Identifier : AIDSLINE MED/97066346
- Piscitelli SC; Flexner C; Minor JR; Polis MA; Masur H; Department of Pharmacy, Warren G. Magnuson Clinical Center, National; Institutes of Health, Bethesda, Maryland, USA.
- Patients with AIDS who are receiving optimal medical care, including combination therapy with antiretroviral agents and more effective prophylaxis and therapy for opportunistic infections and neoplasms, are surviving longer. However, the potential for drug interactions
- Cutaneous miliary tuberculosis in the AIDS era: case report and review.
- Clin Infect Dis. 1996 Oct;23(4):706-10. Unique Identifier : AIDSLINE MED/97066349
- Libraty DH; Byrd TF; Department of Medicine, UCLA School of Medicine, USA.
- Tuberculosis with extrapulmonary manifestations is common in patients with AIDS. The skin is a site of dissemination that has often been overlooked. Historically, cutaneous miliary tuberculosis, also known as tuberculosis cutis miliaris disseminata, was noted to be a rare entity in adults; however, over the past 5 yea
- Clindamycin/primaquine as prophylaxis for Pneumocystis carinii pneumonia.
- Clin Infect Dis. 1996 Oct;23(4):718-22. Unique Identifier : AIDSLINE MED/97066352
- Barber BA; Pegram PS; High KP; Department of Internal Medicine, Bowman Gray School of Medicine of; Wake Forest University, Winston-Salem, North Carolina 27157-1042, USA.
- The records of 206 patients with advanced infection due to human immunodeficiency virus type 1 who were receiving prophylaxis with clindamycin/primaquine (C/P), trimethoprim-sulfamethoxazole TMP-SMZ), or dapsone to prevent Pneumocystis carinii pneumonia PCP) were retrospectively examined. Two hundred sixty-two patient
- Antibody responses to two Epstein-Barr virus (EBV) nuclear antigens (EBNA-1 and EBNA-2) during EBV primary infection in children born to mothers infected with human immunodeficiency virus.
- Clin Infect Dis. 1996 Oct;23(4):806-8. Unique Identifier : AIDSLINE MED/97066367
- Pedneault L; Lapointe N; Alfieri C; Ghadirian P; Carpentier L; Samson J; Joncas J; Department of Microbiology, Hopital Sainte-Justine, Montreal, Quebec,; Canada.
- A variety of antibody response patterns to the latent Epstein-Barr nuclear antigen (EBNA) family have been described in different groups of subjects infected with Epstein-Barr virus EBV). The purpose of this study was to characterize the immune response to two EBNA proteins, EBNA-1 and EBNA-2, in a population of child
- Asymptomatic solitary pulmonary nodules due to Cryptococcus neoformans in patients infected with human immunodeficiency virus.
- Clin Infect Dis. 1996 Oct;23(4):810-2. Unique Identifier : AIDSLINE MED/97066368
- Miller KD; Mican JA; Davey RT; Laboratory of Immunoregulation, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Bethesda, Maryland; 20892, USA.
- We report the cases of three HIV-positive patients with solitary pulmonary nodules caused by Cryptococcus neoformans. Although human infection with C. neoformans occurs via the respiratory tract, isolated pulmonary infection in HIV-positive patients, in contrast with HIV-negative patients, has been thought to be relat
- Enterocytozoon bieneusi infection and diarrheal disease in patients who were not infected with human immunodeficiency virus: case report and review.
- Clin Infect Dis. 1996 Oct;23(4):816-8. Unique Identifier : AIDSLINE MED/97066370
- Wanke CA; DeGirolami P; Federman M; Department of Internal Medicine, New England Deaconess Hospital,; Harvard Medical School, Boston, Massachusetts 02215, USA.
- We describe the identification of the protozoan parasite Enterocytozoon bieneusi in the stool of a patient who was not infected with HIV but who presented with persistent diarrheal disease and severe abdominal complaints. The patient was not infected with HIV but had been noted to have a decreased CD4 cell count since
- Serum cryptococcal antigen in patients with AIDS [editorial]
- Clin Infect Dis. 1996 Oct;23(4):827-30. Unique Identifier : AIDSLINE MED/97066373
- Feldmesser M; Harris C; Reichberg S; Khan S; Casadevall A
- Disseminated Mycobacterium simiae infection in a patient with AIDS: clinical features and treatment.
- Clin Infect Dis. 1996 Oct;23(4):832-3. Unique Identifier : AIDSLINE MED/97066375
- Koeck JL; Debord T; Fabre M; Vincent V; Cavallo JD; Le Vagueresse R; Laboratoire de Biologie Clinique, Hopital d'Instruction des Armees; Dominique Larrey, Versailles, France.
- Cutaneous infection caused by Tsukamurella paurometabolum.
- Clin Infect Dis. 1996 Oct;23(4):839-40. Unique Identifier : AIDSLINE MED/97066381
- Granel F; Lozniewski A; Barbaud A; Lion C; Dailloux M; Weber M; Schmutz JL; Service de Dermatologie, Hopital Fournier, Nancy, France.
- Bilateral staphylococcal axillary lymphadenitis in a man with AIDS.
- Clin Infect Dis. 1996 Oct;23(4):840-1. Unique Identifier : AIDSLINE MED/97066382
- Kaur B; Thurn JR; Filice GA; Infectious Disease Section (111F), Veterans Affairs Medical Center,; Minneapolis, Minnesota 55417, USA.
- Disseminated infection due to multidrug-resistant Mycobacterium bovis in a patient who was seropositive for human immunodeficiency virus.
- Clin Infect Dis. 1996 Oct;23(4):841-3. Unique Identifier : AIDSLINE MED/97066383
- Schultsz C; Kuijper EJ; van Soolingen D; Prins JM; Department of Internal Medicine, Academic Medical Centre, Amsterdam,; The Netherlands.
- Rhinocerebral mucormycosis in a patient with AIDS: a complication of diabetic ketoacidosis following pentamidine therapy.
- Clin Infect Dis. 1996 Oct;23(4):845-6. Unique Identifier : AIDSLINE MED/97066386
- Abril V; Ortega E; Segarra P; Pedro F; Sabater V; Herrera A; Department of Internal Medicine, Hospital General Universitario,; Valencia, Spain.
- Isolated detection of cryptococcal polysaccharide antigen in cerebrospinal fluid samples from patients with AIDS.
- Clin Infect Dis. 1996 Oct;23(4):849-50. Unique Identifier : AIDSLINE MED/97066388
- Manfredi R; Moroni A; Mazzoni A; Nanetti A; Donati M; Mastroianni A; Coronado OV; Chiodo F; Department of Clinical and Experimental Medicine, University of; Bologna, Italy.
- 3'-Azido 3'-deoxythymidine + methotrexate as a novel antineoplastic combination in the treatment of human immunodeficiency virus-related non-Hodgkin's lymphomas.
- Blood. 1997 Jan 15;89(2):419-25. Unique Identifier : AIDSLINE MED/97156553
- Tosi P; Gherlinzoni F; Mazza P; Visani G; Coronado O; Costigliola P; Raise E; Mazzetti M; Gritti F; Chiodo F; Tura S; Istituto di Ematologia 'L. e A. Seragnoli', Policlinico S. Orsola,; Bologna, Italy.
- We have previously reported that 3 -azido 3 -deoxythymidine ( AZT ) can possess a significant antineoplastic activity when combined with drugs that disrupt de novo thymidylate synthesis, such as 5-fluorouracil and methotrexate (MTX). The aim of the pres
- A cysteine protease inhibitor prevents activation-induced T-cell apoptosis and death of peripheral blood cells from human immunodeficiency virus-infected individuals by inhibiting upregulation of Fas ligand [see comments]
- Blood. 1997 Jan 15;89(2):550-7. Unique Identifier : AIDSLINE MED/97156568
- Yang Y; Liu ZH; Ware CF; Ashwell JD; Laboratory of Immune Cell Biology, National Cancer Institute,; Bethesda, MD 20892-1152, USA.
- Activation of T-cell hybridomas, preactivated normal T cells, and peripheral blood lymphocytes (PBL) from human immunodeficiency virus (HIV)-infected individuals results in apoptosis. In the first two cases, apoptosis is caused by the upregulation of Fas ligand (FasL) and its subsequent interaction with Fas; the mecha
- Differential susceptibility to HIV-GP120-sensitized apoptosis in CD4+ T-cell clones with different T-helper phenotypes: role of CD95/CD95L interactions.
- Blood. 1997 Jan 15;89(2):558-69. Unique Identifier : AIDSLINE MED/97156569
- Accornero P; Radrizzani M; Delia D; Gerosa F; Kurrle R; Colombo MP; Division of Experimental Oncology D, Istituto Nazionale Tumori, Milan,; Italy.
- The susceptibility of Th1 and Th2 cell clones to apoptosis following HIV-gp120/CD4 cross-linking and TCR activation was investigated. We show that only Th1 clones are susceptible to HIV-gp120-sensitized apoptosis, although both types of clones express similar levels of CD4 and bind similar amounts of recombinant gp120
- Interleukin-12 (IL-12) production in whole blood cultures from human immunodeficiency virus-infected individuals studied in relation to IL-10 and prostaglandin E2 production.
- Blood. 1997 Jan 15;89(2):570-6. Unique Identifier : AIDSLINE MED/97156570
- Meyaard L; Hovenkamp E; Pakker N; van der Pouw Kraan TC; Miedema F; Department of Clinical Viro-Immunology, Central Laboratory of the; Netherlands Red Cross Blood Transfusion Service, Amsterdam, The; Netherlands.
- The role of interleukin-12 (IL-12) in Th1 cell differentiation is well established. The heterodimer p70, composed of a p40 and a p35 chain, is the biologically active form. IL-12 production by human monocytes is enhanced by interferon-gamma (IFN-gamma) and inhibited by IL-10 and prostaglandin E2 (PGE2). Peripheral blo
- CD3+, CD16+, CD56+ cells: a novel subset of T lymphocytes from patients with Balkanic nephropathy.
- Roum Arch Microbiol Immunol. 1995 Oct-Dec;54(4):255-64. Unique Identifier : AIDSLINE MED/97146216
- Drugarin D; Bona CA; Noveanu L; Schneider F; Tatu C; Department of Physiology, University of Medicine and Pharmacy; Timisoara, Romania.
- Balkanic Nephropathy (BN) is characterized by: an incidence limited to a geographic area; a familial character and a slow progressive evolution towards chronic renal failure associated with the symmetrical reduction of the kidney size. The aim of our study was to find out the immune alterations in BN pathology. The an
- Cardiomyopathy and other symptomatic heart diseases associated with HIV infection.
- Curr Opin Cardiol. 1996 May;11(3):325-31. Unique Identifier : AIDSLINE MED/96432847
- Herskowitz A; Ischemia Research and Education Foundation, San Francisco, CA 94134,; USA.
- Approximately 14 million persons worldwide are estimated to be infected with HIV-1. As more effective therapies have produced longer survival times for HIV-infected patients, new complications of late-stage HIV infection including HIV-related heart disease have emerged. The most common and life-threatening cardiovascu
- Recurrence of Kikuchi's disease with aseptic meningitis in HTLV-1 carrier [editorial; comment]
- Intern Med. 1996 Oct;35(10):753. Unique Identifier : AIDSLINE MED/97087162
- Kikuchi M
- Recurrent histiocytic necrotizing lymphadenitis (Kikuchi's disease) in an human T lymphotropic virus type I carrier [see comments]
- Intern Med. 1996 Oct;35(10):821-5. Unique Identifier : AIDSLINE MED/97087177
- Atarashi K; Yoshimura N; Nodera H; Tsukimoto K; Beppu H; Kanayama M; Department of Internal Medicine, Hiratsuka Kyosai Hospital.
- We describe a case of recurrent histiocytic necrotizing lymphadenitis (HNL) with aseptic meningitis. The patient was a 46-year-old male and a carrier of human T lymphotropic virus type I (HTLV-I). The patient had a past medical history of at least three relapses of HNL. In addition, his sister, who was also an HTLV-I
- Lectin activities of cytokines and growth factors: function and implications for pathology.
- Histol Histopathol. 1996 Oct;11(4):1101-8. Unique Identifier : AIDSLINE MED/97084307
- Zanetta JP; Scior T; Wantyghem J; Wermuth C; Aubery M; Strecker G; Michalski JC; Centre de Neurochimie du CNRS, Strasbourg, France.
- The discovery that certain cytokines have carbohydrate-binding lectin) properties opens new concepts in the understanding of their mechanism of action. The carbohydrate-recognition domain, which is localized opposite to the receptor-binding domain, makes these molecules bi-functional. The expression of the biological
- Chinese clamp down on blood products [news]
- BMJ. 1997 Jan 11;314(7074):93. Unique Identifier : AIDSLINE MED/97159118
- Tomlinson R
- Stable HIV rates hide worrying trends [news]
- BMJ. 1997 Jan 11;314(7074):94. Unique Identifier : AIDSLINE MED/97159121
- Bower H
- AIDS-related primary esophageal lymphoma.
- Abdom Imaging. 1997 Jan-Feb;22(1):11-3. Unique Identifier : AIDSLINE MED/97153435
- Sabate JM; Franquet T; Palmer J; Monill JM; Department of Diagnostic Radiology, Hospital de Sant Pau, Universidad; Autonoma de Barcelona, Avenida Sant Antoni Ma Claret 165, Barcelona; 08025, Spain.
- AIDS-related primary esophageal lymphoma should be considered in the differential diagnosis of a patient with AIDS who presents with dysphagia and a large ulcerated esophageal mass. Endoscopy is mandatory in those patients to establish a definitive diagnosis and to rule out the possibility of an infectious cause of th
- Preliminary crystallographic studies of an anti-HIV-1 protease antibody that inhibits enzyme activity.
- Protein Sci. 1996 May;5(5):966-8. Unique Identifier : AIDSLINE MED/96303819
- Lescar J; Stouracova R; Riottot MM; Chitarra V; Brynda J; Fabry M; Horejsi M; Sedlacek J; Bentley GA; Unite d'Immunologie Structurale, Institut Pasteur, Paris, France.
- F11.2.32, a monoclonal antibody directed against the HIV-1 protease, displays strong inhibitory effects toward the catalytic activity of the enzyme. The antibody cross-reacts with peptides 36-46 and 36-57 from the protease. Crystals of the Fab have been obtained both in the free state and as complexes formed with the
- Lymphocytosis of donor origin in cerebrospinal fluid, and marrow aplasia after donor leukocyte infusion for EBV-lymphoproliferative disease.
- Bone Marrow Transplant. 1996 Jul;18(1):221-4. Unique Identifier : AIDSLINE MED/96428919
- Gharpure V; Rubin L; Amlin J; Emanuel D; Schroeder W; Davidson A; Hromas R; Cornetta K; Department of Medicine, Indiana University School of Medicine,; Indianapolis, USA.
- A 29-year-old woman underwent a T cell-depleted unrelated donor transplant for CML in chronic phase. Sixty-three days after marrow infusion, the patient developed fevers and generalized lymphadenopathy. Lymph node biopsy was consistent with monoclonal EBV-associated immunoblastic lymphoma for which the patient receive
- Request for research proposals. Division of STD Prevention and Control, bureau of HIV/AIDS and STD, Laboratory Centre for Disease Control.
- Can Commun Dis Rep. 1996 Oct 15;22(20):173-4. Unique Identifier : AIDSLINE MED/97154280
- 10th anniversary of the National Reference Laboratory on AIDS in the Czech Republic.
- Cent Eur J Public Health. 1995 Nov;3(4):202-4. Unique Identifier : AIDSLINE MED/97059200
- Bruckova M; Syrucek L; Kopecka D; National Reference Laboratory on AIDS, National Institute of Public; Health, Prague, Czech Republic.
- National Reference Laboratory on AIDS (NRL AIDS) was established in the National Institute of Public Health by the Ministry of Health in the late 1985. At that time the existence of HIV/AIDS and the potencial spread of this infection/disease even in a socialistic country has been officially recognized. The main tasks
- Nasal absorption of 2',3'-didehydro-3'-deoxythymidine (D4T) and its esters in rats.
- Biol Pharm Bull. 1996 Sep;19(9):1234-7. Unique Identifier : AIDSLINE MED/97043978
- Yajima T; Hasegawa T; Juni K; Saneyoshi M; Kawaguchi T; Faculty of Pharmaceutical Sciences, Josai University, Saitama, Japan.
- Nasal absorption of 2 ,3 -didehydro-3 -deoxythymidine (D4T) and its esters (5 -acetyl D4T: C2-D4T and 5 -hemisuccinyl D4T: Suc-D4T) was investigated in rats. Bioavailability of D4T following intranasal (i.n.) administration was 98.0%, and the elimination from plasma was as rapid as that following intravenous administr
- Stargazing: 1997 NOVA Award winners.
- Hosp Health Netw. 1997 Jan 20;71(2):47-50, 52, 54-6. Unique Identifier : AIDSLINE MED/97178233
- Swan H
- Needle exchanges provide useful data [news]
- Aust Nurs J. 1996 Dec-1997 Jan;4(6):16. Unique Identifier : AIDSLINE MED/97177931
- Expression of latent membrane protein 1 in clinically isolated cases and animal models of AIDS-associated non-Hodgkin's lymphomas.
- Pathol Int. 1996 Aug;46(8):568-74. Unique Identifier : AIDSLINE MED/97048389
- Katano H; Morishita Y; Cui LX; Watanabe T; Hirai K; Mori S; Department of Pathology, University of Tokyo, Japan.
- Epstein-Barr virus (EBV)-encoded latent membrane protein 1 (LMP1) is known to be expressed in non-Hodgkin s lymphomas (NHL) occurring in immunocompromised hosts, playing crucial roles in lymphomagenesis. LMP1 expression at the microscopic level, however, was reported to be limited to some, not all, neoplastic cells in
- Epstein-Barr virus-associated post-transplant primary smooth muscle tumor of the liver: report of an autopsy case.
- Pathol Int. 1996 Aug;46(8):601-4. Unique Identifier : AIDSLINE MED/97048394
- Sadahira Y; Moriya T; Shirabe T; Matsuno T; Manabe T; Department of Pathology, Kawasaki Medical School, Kurashiki, Japan.
- Epstein-Barr (EB) virus-associated primary smooth muscle tumors have been reported in immunosuppressed young patients with acquired immunodeficiency syndrome (AIDS) and young people who have undergone liver transplantation. An autopsy case of EB virus-associated smooth muscle cell tumor in a 21 year old female who rec
- The immunologic aspects of human immunodeficiency virus infection in the gastrointestinal tract.
- Semin Gastrointest Dis. 1996 Jan;7(1):19-29. Unique Identifier : AIDSLINE MED/97059255
- Schneider T; Ullrich R; Zeitz M; Medical Clinic II, University of the Saarland, Homburg/Saar, Berlin,; Germany.
- The intestinal (in particular rectal) mucosa is an important portal of entry of human immunodeficiency virus (HIV) in homosexual men, who represent the vast majority of HIV-infected patients in Europe and North America. There are several possibilities for HIV to reach the CD4+ T cells, macrophages, and follicular dend
- Cyclophilin A complexed with a fragment of HIV-1 gag protein: insights into HIV-1 infectious activity.
- Structure. 1997 Jan 15;5(1):139-46. Unique Identifier : AIDSLINE MED/97169450
- Zhao Y; Chen Y; Schutkowski M; Fischer G; Ke H; Department of Biochemistry and Biophysics, School of Medicine, The; University of North Carolina, Chapel Hill, NC 27599, USA.
- BACKGROUND: Cyclophilin A (CyPA), a receptor of the immunosuppressive drug cyclosporin A, catalyzes the cis-trans isomerization of peptidyl-prolyl bonds and is required for the infectious activity of human immunodeficiency virus type 1 HIV-1). The crystal structure of CyPA complexed with a fragment of the HIV-1 gag pr
- Role REVersal: understanding how RRE RNA binds its peptide ligand.
- Structure. 1997 Jan 15;5(1):7-11. Unique Identifier : AIDSLINE MED/97169439
- Grate D; Wilson C; Department of Biology, University of California at Santa Cruz, 1156; High Street, Santa Cruz, CA 95064, USA. grate@biology.ucsc.edu
- The structure of a complex between the HIV Revresponsive element RRE) RNA and a fragment of the Rev protein has recently been determined by NMR. Together with previous studies of the Tat-TAR complex, these results show how RNA elements with considerable tertiary structure are able to play a more active role in directi
- HIV-1: is Nef a PAK animal?
- Curr Biol. 1996 Dec 1;6(12):1557-9. Unique Identifier : AIDSLINE MED/97148179
- Cullen BR; Howard Hughes Medical Institute, Durham, North Carolina, USA.
- HIV-1 Nef is clearly essential for efficient viral replication in vivo, but it has been difficult to determine why. Recent evidence that Nef specifically activates a PAK-dependent signalling cascade may be the first step in defining the mechanism of action of this enigmatic viral protein.
- CDC42 and Rac1 are implicated in the activation of the Nef-associated kinase and replication of HIV-1.
- Curr Biol. 1996 Dec 1;6(12):1677-84. Unique Identifier : AIDSLINE MED/97148201
- Lu X; Wu X; Plemenitas A; Yu H; Sawai ET; Abo A; Peterlin BM; Howard Hughes Medical Institute, University of California at San; Francisco, California, USA.
- BACKGROUND: The negative factor (Nef) of human and simian immunodeficiency viruses (HIV-1, HIV-2 and SIV) is required for high levels of viremia and progression to AIDS. Additionally, Nef leads to cellular activation, increased viral infectivity and decreased expression of CD4 on the cell surface. Previously, we and o
- Unusual presentation of a tuberculous peritonitis in a patient with concomitant AIDS and liver cirrhosis.
- Eur J Gastroenterol Hepatol. 1996 Oct;8(10):1021-2. Unique Identifier : AIDSLINE MED/97084227
- Turner L; Dupont C; Lesur G; Barthod F; Moreau D; Rouveix E; Dorra M; Department of Medicine, Hopital Ambroise Pare, Boulogne, France.
- We report a case of tuberculous peritonitis in a patient with concomitant HIV infection and liver cirrhosis. A 50-year-old man with viral B and delta liver cirrhosis and AIDS was diagnosed with spontaneous Escherichia coli peritonitis and successfully treated with beta-lactamins. Three months later, ascites reappeared
- New trends in the drug therapy of localized and disseminated Mycobacterium avium complex infection [see comments]
- Am J Health Syst Pharm. 1996 Nov 1;53(21):2585-90. Unique Identifier : AIDSLINE MED/97070461
- Sesin GP; Manzi SF; Pacheco R; Charlton Memorial Hospital, Fall River, MA 02720, USA.
- Recent advances in the drug therapy of localized and disseminated infection with Mycobacterium avium complex (MAC) are reviewed. MAC infection is the most commonly reported bacterial infection in patients with AIDS, and the frequency of this infection in patients negative for the human immunodeficiency virus (HIV) is
- HLA allele selection for designing peptide vaccines.
- Genet Anal. 1996 Sep;13(3):81-6. Unique Identifier : AIDSLINE MED/97085921
- Gulukota K; DeLisi C; Department of Biomedical Engineering, Boston University, MA 02215,; USA. gulu@bu.edu
- A central problem in developing vaccines against rapidly evolving viruses such as HIV and Influenza is the mutability of their antigens. In principle, the problem can be mitigated by using peptides from conserved portions of viral proteins. However, because cytotoxic T lymphocytes (CTLs), which such vaccines would sti
- Patients with HIV infection and end-stage renal disease.
- Adv Ren Replace Ther. 1996 Oct;3(4):287-92. Unique Identifier : AIDSLINE MED/97071845
- Schoenfeld P; Rodriguez R; Mendelson M; University of California Renal Center, San Francisco, USA.
- There has been a steady increase in the number of dialysis patients with human immunodeficiency viral (HIV) infection. HIV-associated nephropathy (HIVAN) is the most common cause of end-stage renal disease in this patient population. Although the major potential category of risk of HIV transmission is from the dialysi
- HIV infection: challenges for dialysis personnel.
- Adv Ren Replace Ther. 1996 Oct;3(4):293-7. Unique Identifier : AIDSLINE MED/97071846
- Bradley-Springer L; New Mexico AIDS Education and Training Center, Albuquerque 87131, USA.
- Patients with human immunodeficiency viral (HIV) infection who also require dialysis present a complex constellation of challenges for dialysis personnel. The major challenges that health care providers (HCPs) face when working with HIV-infected patients are related to overcoming personal fears and to adapting to HIV-
- Disposal of dialysate in HIV-positive patients: an update.
- Adv Ren Replace Ther. 1996 Oct;3(4):298-301. Unique Identifier : AIDSLINE MED/97071847
- Scheel PJ Jr; Malan M; Department of Medicine Johns Hopkins Medical Institutions, Baltimore,; MD, USA.
- One of the concerns with the use of peritoneal dialysis in human immunodeficiency virus (HIV)-positive patients is disposal of the peritoneal effluents. This article reviews survival characteristics of HIV in dialysate effluents and current disinfectant strategies.
- An evaluation of dipstick-dot immunoassay in the detection of antibodies to HIV-1 and 2 in Zimbabwe.
- Trop Med Int Health. 1997 Jan;2(1):83-8. Unique Identifier : AIDSLINE MED/97171032
- Ray CS; Mason PR; Smith H; Rogers L; Tobaiwa O; Katzenstein DA; Zimbabwe AIDS Prevention Project, University of Zimbabwe, Harare,; Zimbabwe.
- There is a need, in many developing countries, for simple and inexpensive HIV serology tests for use at the district level of health care. The Programme for Appropriate Technology in Health has developed a simple dipstick ELISA to detect antibodies to HIV-1 and 2, at a cost considerably lower than current ELISAs, whic
- HIV postexposure prophylaxis: new recommendations [see comments]
- Can Med Assoc J. 1997 Jan 15;156(2):233-4. Unique Identifier : AIDSLINE MED/97164966
- Patrick DM; British Columbia Centre for Disease Control Vancouver, BC.
- Kit helps physicians, women work together to weigh HRT risks, benefits.
- Can Med Assoc J. 1997 Jan 15;156(2):248-50. Unique Identifier : AIDSLINE MED/97164971
- Robinson A
- The Ottawa Health Decision Centre is developing a line of decision AIDS to make it easier for physicians to discuss potential therapies with patients. The first kit, Making choices: hormones after menopause, helps women weigh the risks and benefits of hormone replacement therapy.
- Anti-HTLV-1 antibody positive cutaneous T-cell lymphoma.
- Cancer. 1997 Jan 15;79(2):269-74. Unique Identifier : AIDSLINE MED/97163265
- Kikuchi A; Ohata Y; Matsumoto H; Sugiura M; Nishikawa T; Department of Dermatology, Keio University School of Medicine, Tokyo,; Japan.
- BACKGROUND: Adult T-cell leukemia/lymphoma (ATLL) is a neoplasm of the mature helper T-lymphocyte. Human T-lymphotropic virus type 1 (HTLV-1) has been shown to be the cause of this neoplasm. Recently, however, the HTLV-1 genome has been found in some patients with cutaneous T-cell lymphoma (CTCL), which suggests a cau
- Denver HIV/AIDS demonstration program--project SNAPP is a winner!
- Colo Nurse. 1996 Dec;96(4):33. Unique Identifier : AIDSLINE MED/97177954
- Moorhouse M
- Oxidative stress in blood of HIV infected patients.
- Clin Chim Acta. 1996 Nov 29;255(2):107-17. Unique Identifier : AIDSLINE MED/97092089
- Repetto M; Reides C; Gomez Carretero ML; Costa M; Griemberg G; Llesuy S; National Laboratory of Free Radical Biology, Catedra de Quimica; General e Inorganica, Facultad de Farmacia y Bioquimica, Universidad; de Buenos Aires, Argentina.
- The oxidative stress in human erythrocytes was studied in asymptomatic and symptomatic patients infected by the human immunodeficiency virus (HIV), and patients with the acquired immunodeficiency syndrome (AIDS). tert-Butyl hydroperoxide initiated chemiluminescence, superoxide dismutase and catalase activities, and to
- Escape of HIV-1 is associated with lack of V3 domain-specific antibodies in vivo.
- Clin Exp Immunol. 1997 Jan;107(1):15-20. Unique Identifier : AIDSLINE MED/97163431
- Schreiber M; Muller H; Wachsmuth C; Laue T; Hufert FT; Van Laer MD; Schmitz H; Medical Microbiology Section, Department of Virology, Bernhard Nocht; Institute for Tropical Medicine, Hamburg, Germany.
- This study was performed to analyse correlates of viral escape in AIDS patients. Peripheral blood mononuclear cells (PBMC) from HIV- donors were inoculated with AIDS patients serum to detect neutralization-resistant cell-free virus. Infectious virus was detected by polymerase chain reaction (PCR) and analysed by sequ
- Relevance of local Th2-type cytokine mRNA expression in immunocompetent infiltrates in inflamed gingival tissue to periodontal diseases.
- Clin Exp Immunol. 1997 Jan;107(1):166-74. Unique Identifier : AIDSLINE MED/97163452
- Tokoro Y; Matsuki Y; Yamamoto T; Suzuki T; Hara K; Department of Periodontology, Niigata University School of Dentistry,; Japan.
- It has been suggested that the types of inflammatory round cell infiltrates and the divergence in the cytokine production profile by macrophages and helper T cells regulate the course of infectious or inflammatory diseases, including periodontitis and gingivitis. We examined the expression of IL-1alpha, IL-1beta,
- T cell receptor (TCR) BV gene repertoires and clonal expansions of CD4 cells in patients with HIV infections.
- Clin Exp Immunol. 1997 Jan;107(1):21-30. Unique Identifier : AIDSLINE MED/97163432
- Roglic M; Macphee RD; Duncan SR; Sattler FR; Theofilopoulos AN; Department of Immunology, The Scripps Research Institute, La Jolla, CA; 92037, USA.
- Despite extensive investigation, the pathogenesis of T cell depletions that characterize AIDS has not been elucidated. To study this process further, we evaluated T cell antigen receptor beta-chain variable gene (TCRBV) repertoires in peripheral blood lymphocytes (PBL) of 23 HIV-infected patients. Expression levels of
- Progression of HIV disease is associated with increased expression of Fc gammaRI and CR1 on alveolar macrophages.
- Clin Exp Immunol. 1997 Jan;107(1):31-6. Unique Identifier : AIDSLINE MED/97163433
- Gilbody J; Lipman MC; Johnson MA; Atkins M; Poulter LW; Department of Clinical Immunology, Royal Free Hospital and School of; Medicine, London, UK.
- The expression of receptors for complement and the Fc region of immunoglobulin by alveolar macrophages (AM) constitutes a valuable aid to effector function of these cells. However, during HIV infection such expression may also act to increase binding of immune complexes, thus facilitating viral infection of these cell
- Modulation of lymphocyte and monocyte activity after intravenous immunoglobulin administration in vivo.
- Clin Exp Immunol. 1997 Jan;107(1):50-6. Unique Identifier : AIDSLINE MED/97163436
- Aukrust P; Muller F; Nordoy I; Haug CJ; Froland SS; Medical Department A and Research Institute for Internal Medicine,; University of Oslo, The National Hospital, Rikshospitalet, Norway.
- In 12 patients with primary hypogammaglobulinaemia we investigated the in vivo effect of one bolus injection (400 mg/kg) of intravenous immunoglobulin (IVIG) on lymphocyte subsets and monocytes in peripheral blood, on plasma levels of soluble factors reflecting monocyte and lymphocyte activity and on lymphocyte prolif
- Comparative brain pathology of HIV-seronegative and HIV-infected drug addicts.
- Clin Neuropathol. 1996 Nov-Dec;15(6):324-9. Unique Identifier : AIDSLINE MED/97092113
- Makrigeorgi-Butera M; Hagel C; Laas R; Puschel K; Stavrou D; Department of Neuropathology, University of Hamburg, Germany.
- Early stages of infection with human immunodeficiency virus (HIV) were studied in HIV-seropositive drug addicts. Since heroin users are immunocompromized even in the absence of HIV infection, the aim of the present study was to compare the morphological alterations present in HIV-seronegative and HIV-seropositive drug
- Vascular changes in the cerebral cortex in HIV-1 infection: I. A morphometric investigation by light and electron microscopy.
- Clin Neuropathol. 1996 Nov-Dec;15(6):361-6. Unique Identifier : AIDSLINE MED/97092120
- Weis S; Haug H; Budka H; Institute of Neuropathology, Ludwig-Maximilians-University, Munich,; Germany.
- The microvasculature of the cerebral cortex in AIDS brains was investigated by means of stereology at the light and electron microscopic levels. Stereologic parameters for microvessels were determined in formalin-fixed autopsy tissue of 24 AIDS patients and of 35 age- and sex-matched controls. At the light microscopic
- A pooled analysis of CD4 response to zidovudine and zalcitabine treatment in patients with AIDS and AIDS-related complex.
- Clin Pharmacol Ther. 1997 Jan;61(1):70-82. Unique Identifier : AIDSLINE MED/97176636
- Gries JM; Troconiz IF; Verotta D; Jacobson M; Sheiner LB; Department of Biopharmaceutical Sciences, School of Pharmacy,; University of California, San Francisco 94143-0446, USA.
- INTRODUCTION: This article reports a meta-analysis focused on the efficacy of zalcitabine and zidovudine alone or in combination as reported by three AIDS Clinical Trial Group trials. We analyzed the log CD4 count (LCD4) response to therapy up to 1 year after the beginning of therapy. One of the purposes of this artic
- Dangerousness and dentistry: an explanation of dentists' reactions and responses to the treatment of HIV-seropositive patients.
- Community Dent Oral Epidemiol. 1996 Oct;24(5):341-5. Unique Identifier : AIDSLINE MED/97112541
- Gibson BJ; Freeman R; Dental Public Health Research Group, School of Clinical Dentistry,; Queen's University of Belfast, N. Ireland.
- Factors which influence health professional s willingness to treat HIV seropositive patients have been explained in terms of the concept of dangerousness. Can this concept be used as a vehicle to explain dentists responses? All dentists currently in practice in Northern
- Persistent activation of CD8+ T-cells characterizes prediabetic twins.
- Diabetes Care. 1996 Nov;19(11):1177-84. Unique Identifier : AIDSLINE MED/97064826
- Peakman M; Leslie RD; Alviggi L; Hawa M; Vergani D; Department of Immunology, King's College School of Medicine and; Dentistry, London, U.K.
- OBJECTIVE: Elevated circulating levels of activated CD3+ T-cells are characteristic of type I diabetes at diagnosis, and activated CD8+ (cytotoxic/suppressor) T-cells predominate in the islet infiltrate. The aim of this study was to examine the peripheral blood of prediabetic and nondiabetic identical twins of patient
- Substance abuse treatment entry, retention and effectiveness: out-of-treatment opiate injection drug users.
- Drug Alcohol Depend. 1996 Sep;42(1):11-20. Unique Identifier : AIDSLINE MED/97044328
- Booth RE; Crowley TJ; Zhang Y; Department of Psychiatry, School of Medicine, University of Colorado; Health Sciences Center, Denver 80211, USA.
- This study was designed to assess the effect of client characteristics and community interventions on treatment entry and retention, and to evaluate the relative effectiveness of treatment, compared to other interventions, in reducing drug use and crime among out-of-treatment opiate injectors. Subjects (N = 2973) from
- Crack cocaine smokers who turn to drug injection: characteristics, factors associated with injection, and implications for HIV transmission. The Multicenter Crack Cocaine and HIV Infection Study Team.
- Drug Alcohol Depend. 1996 Oct;42(2):85-92. Unique Identifier : AIDSLINE MED/97044336
- Irwin KL; Edlin BR; Faruque S; McCoy HV; Word C; Serrano Y; Inciardi J; Bowser B; Holmberg SD; Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
- A survey of 1220 street-recruited crack cocaine smokers revealed that crack smokers may turn to drug injection to ease crack withdrawal. Crack smokers who later injected tended to smoke crack more heavily and for longer periods than those who did not inject. The initiation of injection was significantly associated wit
- Cytomegalovirus ileocolitis: different manifestations of the same illness in the terminal ileum and colon.
- Endoscopy. 1996 Oct;28(8):729. Unique Identifier : AIDSLINE MED/97088160
- Sebastian JJ; Uribarrena R; Gastroenterology Dept., Miguel Servet Hospital, Zaragoza, Spain.
- Statistical methods for the blood beryllium lymphocyte proliferation test.
- Environ Health Perspect. 1996 Oct;104 Suppl 5:957-68. Unique Identifier : AIDSLINE MED/97087013
- Frome EL; Smith MH; Littlefield LG; Neubert RL; Colyer SP; Computer Science and Mathematics Division, Oak Ridge National; Laboratory, Tennessee 37831-6367, USA. fromeel@ornl.gov
- The blood beryllium lymphocyte proliferation test (BeLPT) is a modification of the standard lymphocyte proliferation test that is used to identify persons who may have chronic beryllium disease. A major problem in the interpretation of BeLPT test results is outlying data values among the replicate well counts approxim
- Prospective evaluation of fever of unknown origin in patients infected with the human immunodeficiency virus. Grupo Andaluz para el Estudio de las Enfermedades Infecciosas.
- Eur J Clin Microbiol Infect Dis. 1996 Sep;15(9):705-11. Unique Identifier : AIDSLINE MED/97081324
- Lozano F; Torre-Cisneros J; Bascunana A; Polo J; Viciana P; Garcia-Ordonez MA; Hernandez-Quero J; Marquez M; Vergara A; Diez F; Pujol E; Torres-Tortosa M; Pasquau J; Hernandez-Burruezo JJ; Suarez I; Infectious Diseases Section, Hospital Universitario de Valme, Seville,; Spain.
- The aim of this study was to determine the frequency and aetiology of fever of unknown origin (FUO) in patients infected with the human immunodeficiency virus (HIV), to assess the value of the tests used in its diagnosis, and to evaluate possible models of diagnosis for the causes found most frequently. One hundred tw
- Isolation of Bartonella quintana from an HIV-positive patient with bacillary angiomatosis.
- Eur J Clin Microbiol Infect Dis. 1996 Sep;15(9):736-41. Unique Identifier : AIDSLINE MED/97081329
- Schmidt HU; Kaliebe T; Poppinger J; Buhler C; Sander A; Institut fur Medizinische Mikrobiologie, Krankenhaus; Munchen-Schwabing, Germany.
- Bartonella quintana was grown from a lysis-centrifugation blood culture of an HIV-positive man who presented with lesions of bacillary angiomatosis in skin and bones. The isolate was identified by sodium dodecylsulfate-polyacrylamide gel electrophoresis, 16S rRNA gene sequenc
- Sexual behaviour and multiple infections in drug abusers.
- Eur J Epidemiol. 1996 Oct;12(5):429-35. Unique Identifier : AIDSLINE MED/97061271
- Coppola RC; Masia G; di Martino ML; Carboni G; Muggianu E; Piro R; Manconi PE; Department of Hygiene and Public Health, University of Cagliari,; Italy.
- We have studied the prevalence and the serological profile of HBV, HCV, HDV and HIV infections in 137 Italian subjects addicted to the intravenous use of heroine and correlated the virological findings with sexual behaviour. HBV and HCV viremia were also measured in 114 patients. Anti-HCV was detected in 81% of the ad
- Vertical transmission of hepatitis C virus: an epidemiological study on 2,980 pregnant women in Italy.
- Eur J Epidemiol. 1996 Oct;12(5):443-7. Unique Identifier : AIDSLINE MED/97061273
- Sabatino G; Ramenghi LA; di Marzio M; Pizzigallo E; Department of Pediatrics-Neonatal Intensive Care Unit, G. D' Annunzio; University, Chieti, Italy.
- The risk of mother-to-infant transmission of hepatitis C virus HCV) varies according to the population studied and the tests used. Aim of the current study was to investigate HCV vertical transmission rate in children born to 30 HCV positive/HIV negative pregnant women in Italy . We
- Direct activation of protein phosphatase-2A0 by HIV-1 encoded protein complex NCp7:vpr.
- FEBS Lett. 1997 Jan 20;401(2-3):197-201. Unique Identifier : AIDSLINE MED/97165993
- Tung HY; De Rocquigny H; Zhao LJ; Cayla X; Roques BP; Ozon R; Laboratoire de Physiologie de la Reproduction, CNRS URA 1449, INRA,; Universite Pierre et Marie Curie, Paris, France.; ltung@hall.snv.jussieu.fr
- The effects of HIV-1 encoded proteins NCp7, vpr and NCp7:vpr complex on the activity of protein phosphatase-2A0 have been tested. We report that NCp7 is an activator of protein phosphatase-2A0 and that vpr activated protein phosphatase-2A0 only slightly. We also report that NCp7 and vpr form a tight complex which beco
- Development of a novel drug-delivery system using bacteriophage MS2 capsids.
- Biochem Soc Trans. 1996 Aug;24(3):413S. Unique Identifier : AIDSLINE MED/97033210
- Wu M; Brown WL; Hill HR; Stockley PG; Department of Biology, University of Leeds, UK.
- [Serum cardiolipin antibodies in patients with alcoholic cirrhosis]
- Gastroenterol Clin Biol. 1996;20(10):736-42. Unique Identifier : AIDSLINE MED/97145500
- Gervais A; Czernichow B; Grunebaum L; Wiesel ML; Auperin A; Rivalland D; Gabanyi J; Goldstein L; Cazenave JP; Doffoel M; Service d'Hepato-Gastroenterologie, Hopital Civil, Strasbourg.
- OBJECTIVE: Although portal obstruction is a complication in cirrhosis which is usually associated with hepatocellular carcinoma, its precise neoplastic or thrombotic nature is not easy to determine. Serum antiphospholipid antibodies could be involved in thrombosis-related portal obstruction. PATIENTS AND METHODS: The
- Outpatient therapeutic ERCP: a series of 262 consecutive cases.
- Gastrointest Endosc. 1996 Oct;44(4):443-9. Unique Identifier : AIDSLINE MED/97061336
- Mehta SN; Pavone E; Barkun AN; Montreal General Hospital, Quebec, Canada.
- BACKGROUND: Because of possible complications, it has been common practice to admit most if not all patients undergoing therapeutic ERCP. Therefore, little descriptive data exist on the safety of outpatient therapeutic ERCP. METHODS: We assessed 262 consecutive ERCPs in 209 patients undergoing outpatient therapeutic E
- T-cell lymphoma in Hashimoto's thyroiditis.
- Histopathology. 1996 Nov;29(5):455-9. Unique Identifier : AIDSLINE MED/97109211
- Abdul-Rahman ZH; Gogas HJ; Tooze JA; Anderson B; Mansi J; Sacks NP; Finlayson CJ; Department of Histopathology, St George's Hospital, London, UK.
- An elderly Caucasian woman with a 2-year-history of hypothyroidism, treated with thyroxine, presented with a rapidly growing mass in the thyroid. The morphological and immunological features of this thyroid tumour were those of a peripheral T-cell lymphoma with an immunophenotype commonly associated with HTLV-1 positi
- The potential roles of endogenous retroviruses in autoimmunity.
- Immunol Rev. 1996 Aug;152:193-236. Unique Identifier : AIDSLINE MED/97084330
- Nakagawa K; Harrison LC; Burnet Clinical Research Unit, Walter and Eliza Hall Institute of; Medical Research, Royal Melbourne Hospital, Parkville, Australia.
- Endogenous retroviruses (ERVs) are estimated to comprise up to 1% of human DNA. While the genome of many ERVs is interrupted by termination codons, deletions or frame shift mutations, some ERVs are transcriptionally active and recent studies reveal protein expression or particle formation by human ERVs. ERVs have been
- Flavivirus-induced up-regulation of MHC class I antigens; implications for the induction of CD8+ T-cell-mediated autoimmunity.
- Immunol Rev. 1996 Aug;152:5-19. Unique Identifier : AIDSLINE MED/97084321
- Lobigs M; Blanden RV; Mullbacher A; Division of Immunology and Cell Biology, John Curtin School of Medical; Research, Australian National University, Canberra, Australia.
- Infection of a wide variety of cells of human, mouse and other species origin by flaviviruses such as WNV, YF, Den, MVE, KUN and JE, increases the cell-surface expression of MHC class I. This MHC class I up-regulation is not due to increased MHC class I synthesis per se, but the result of increased peptide availabili
- A role for B cells in resistance to Cryptococcus neoformans in mice.
- Infect Immun. 1997 Feb;65(2):525-30. Unique Identifier : AIDSLINE MED/97162321
- Aguirre KM; Johnson LL; Trudeau Institute, Saranac Lake, New York 12983, USA.
- The role of B cells in immunity to Cryptococcus neoformans was investigated. Genetically targeted, B-cell-deficient mice (mu Mt) examined at various times after intravenous infection with C. neoformans 184 had lung and brain yeast burdens that were equivalent to tissue burdens in control B-cell-sufficient mice. Both B
- Th1 and Th2 cytokines in mice with invasive aspergillosis.
- Infect Immun. 1997 Feb;65(2):564-70. Unique Identifier : AIDSLINE MED/97162327
- Cenci E; Perito S; Enssle KH; Mosci P; Latge JP; Romani L; Bistoni F; Microbiology Section, Department of Experimental Medicine and; Biochemical Sciences, University of Perugia, Italy.
- With a murine model of invasive aspergillosis we investigated cytokine production by CD4+ T helper cells and the effects of cytokine administration or neutralization on the course and outcome of infection. Patterns of susceptibility and resistance to infection were obtained with different strains of mice injected with
- Oral carriage of Candida albicans in murine AIDS.
- Infect Immun. 1997 Feb;65(2):661-7. Unique Identifier : AIDSLINE MED/97162341
- Deslauriers N; Cote L; Montplaisir S; de Repentigny L; Faculty of Dental Medicine, Laval University, Quebec, Canada.
- Oral candidiasis is a common fungal infection in patients infected with the human immunodeficiency virus (HIV). Although rare at the time of primary HIV infection, it is frequently found throughout the asymptomatic phase and is predictive of progressive immunodeficiency. However, the precise immune defect which result
- Induction of cytotoxic T-cell responses against culture filtrate antigens in Mycobacterium bovis bacillus Calmette-Guerin-infected mice.
- Infect Immun. 1997 Feb;65(2):676-84. Unique Identifier : AIDSLINE MED/97162343
- Denis O; Lozes E; Huygen K; Laboratory of Mycobacterial Immunology, Pasteur Institute of Brussels,; Belgium.
- CD8+ T cells are essential for protection against mycobacteria, as is clearly demonstrated by the fatal outcome of experimental infection of beta-2 microglobulin knockout mice. However, the mechanisms and antigens (Ags) leading to CD8+ T-cell activation and regulation have been poorly characterized. Here we show that,
- Herpes simplex virus type 2 in Brazil: seroepidemiologic survey.
- Int J Dermatol. 1996 Nov;35(11):794-6. Unique Identifier : AIDSLINE MED/97072984
- Da Rosa-Santos OL; Goncalves Da Silva A; Pereira AC Jr; Department of Medical Clinics (Dermatology), Clementino Fraga Filho; University Hospital, Rio de Janeiro, Brazil.
- BACKGROUND: The incidence of genital herpes is increasing worldwide. Herpes simplex virus type 2 (HSV-2) is the most common cause of genital ulcerations among the sexually transmitted diseases (STDS). In order to investigate the sexual transmission of genital herpes infection in
- Nodular Kaposi's sarcoma as a presenting feature of HIV infection.
- Int J Dermatol. 1996 Nov;35(11):813-5. Unique Identifier : AIDSLINE MED/97072990
- Gonzalez-Martinez R; Marin-Bertolin S; Martinez-Escribano J; Amorrortu-Velayos J; Department of Plastic and Reconstructive Surgery, University General; Hospital, Valencia, Spain.
- Kaposi's sarcoma and sarcoidosis coexisting in lesions of HIV-seronegative patient.
- Int J Dermatol. 1996 Nov;35(11):824-6. Unique Identifier : AIDSLINE MED/97072995
- Dessoukey MW; Dayem HA; Omer MF; Department of Dermatology, Al-Jazeira Hospital, Abu-Dhabi, United Arab; Emirates.
- Advanced epidemic Kaposi's sarcoma: treatment with bleomycin or combination of doxorubicin, bleomycin, and vincristine.
- Int J Dermatol. 1996 Nov;35(11):831-3. Unique Identifier : AIDSLINE MED/97072998
- Hernandez DE; Perez JR; Department of Medicine, Vargas Medical School, Hospital Vargas,; Universidad Central de Venezuela, Caracas, Venezuela.
- BACKGROUND: Systemic chemotherapy is a treatment modality in the management of epidemic Kaposi s sarcoma (EKS). We conducted a prospective trial to compare bleomycin as a single agent with a regimen of low-dose doxorubicin, bleomycin, and vincristine (ABV) in patients with advanced EKS. METHODS: Twenty-four homosexual
- Antioxidant vitamins and immunodeficiency.
- Int J Vitam Nutr Res. 1996;66(2):141-5. Unique Identifier : AIDSLINE MED/97000959
- Mastroiacovo P; Ajassa C; Berardelli G; Bruni R; Catania N; Fidanza A; Pace V; Zanzoglous S; Institute of General Physiology, La Sapienza University, Rome, Italy.
- On the plasma of 20 children from 1 to 6 years old with HIV infection, the following analyses were carried out: vitamin assays (vitamin E and beta-carotene), hematochemical assays, and immunoassays. From the body of our results it emerged that in the seropositive children considered, in addition to the already well-kn
- New therapies for cytomegalovirus retinitis.
- Int Ophthalmol Clin. 1996 Spring;36(2):1-9. Unique Identifier : AIDSLINE MED/97107904
- Schwartz DM; Department of Ophthalmology, University of California, San Francisco; 94143, USA.
- A phase II study of weekly oral methotrexate and zidovudine (AZT) in advanced adenocarcinoma of the pancreas and hepatocellular carcinoma.
- Invest New Drugs. 1996;14(2):207-12. Unique Identifier : AIDSLINE MED/97070916
- Miller KD; Loehrer PJ; Gonin R; Weber G; Ansari R; Pletcher W; McClean J; Spiridonidis CH; Mortimer J; Department of Medicine, Indiana University Medical Center,; Indianapolis, USA.
- From January 1992 through May 1993, 31 patients with adenocarcinoma of the pancreas or hepatocellular carcinoma were treated with weekly oral methotrexate (7.5 mg/M2 every 6 hours for 6 doses) and continuous oral AZT (200 mg four times daily). Patient
- Pharmacokinetic profile of Mitoguazone (MGBG) in patients with AIDS related non-Hodgkin's lymphoma.
- Invest New Drugs. 1996;14(2):227-34. Unique Identifier : AIDSLINE MED/97070920
- Rizzo J; Levine AM; Weiss GR; Pearce T; Kraynak M; Mueck R; Smith S; Von Hoff DD; Kuhn JG; Cancer Therapy and Research Center, San Antonio, TX, 78229, USA.
- Mitoguazone is a unique chemotherapeutic agent whose activity is believed to result primarily from the competitive inhibition of S-adenosyl-methionine decarboxylase leading to a disruption in polyamine biosynthesis. Initial clinical trials demonstrated that the dose-limiting toxicities (mucositis and myelosuppression)
- [Plasmapheresis and immunopathogenetic aspects of toxic epidermal necrolysis]
- Hautarzt. 1996 Oct;47(10):749-53. Unique Identifier : AIDSLINE MED/97095312
- Hermes B; Haas N; Henz BM; Hautklinik, Virchow-Klinikum, Humboldt-Universitat zu Berlin.
- Drug-induced toxic epidermal necrolysis (TEN) is a rare but frequently lethal disease of the skin and mucosa of unknown etiology. Toxic metabolic and immunologic products in the serum have been discussed as possible causes. For this reason we have performed plasmapheresis on these patients for many years. Results rega
- [HIV-associated skin diseases. 1: Follow-up and epidemiology of HIV infection, pathogen-induced HIV-associated dermatoses]
- Hautarzt. 1996 Oct;47(10):795-813. Unique Identifier : AIDSLINE MED/97095322
- Ramsauer J; Plettenberg A; Meigel W; Abteilung fur Dermatologie, Allgemeines Krankenhaus St. Georg,; Hamburg.
- In-vitro activity of macrolides alone and in combination with artemisin, atovaquone, dapsone, minocycline or pyrimethamine against Cryptosporidium parvum.
- J Antimicrob Chemother. 1996 Sep;38(3):399-408. Unique Identifier : AIDSLINE MED/97044644
- Giacometti A; Cirioni O; Scalise G; Institute of Infectious Diseases and Public Health, University of; Ancona, Italy.
- The anticryptosporidial activity of four macrolides alone and in combination with other antimicrobial agents was investigated against ten clinical isolates of Cryptosporidium parvum recovered from stools of AIDS patients. The susceptibility tests were performed by inoculation of the protozoa on to cell monolayers and
- Multi-drug resistant non-typhi salmonellae in Kenya.
- J Antimicrob Chemother. 1996 Sep;38(3):425-34. Unique Identifier : AIDSLINE MED/97044646
- Kariuki S; Gilks C; Corkill J; Kimari J; Benea A; Waiyaki P; Hart CA; Department of Medical Microbiology, School of Tropical Medicine,; University of Liverpool, UK.
- Two methods of plasmid characterization, restriction digest patterns and incompatibility grouping, were used to study self-transmissible multi-drug resistance among non-typhi salmonellae (NTS). Resistance to ampicillin and other commonly applied beta-lactams was evaluated by iso-electric focusing and disc inactivation
- Comparative activity of azithromycin against clinical isolates of mycobacteria.
- J Antimicrob Chemother. 1996 Sep;38(3):539-42. Unique Identifier : AIDSLINE MED/97044656
- Watt B; Rayner A; Harris G; Scottish Mycobacteria Reference Laboratory, City Hospital, Edinburgh,; UK.
- Azithromycin exhibited in-vitro activity against 20 clinical isolates of Mycobacterium avium complex for which the MIC90 was 32 mg/L and 22 clinical isolates of other mycobacteria but showed no activity against 20 isolates of Mycobacterium tuberculosis MIC90 > 128 mg/L) nor against the single isolate of Mycobacterium
- Preferential binding of poly(A)-binding protein 1 to an inhibitory RNA element in the human immunodeficiency virus type 1 gag mRNA.
- J Biol Chem. 1997 Jan 24;272(4):2307-11. Unique Identifier : AIDSLINE MED/97153004
- Afonina E; Neumann M; Pavlakis GN; Human Retrovirus Section, ABL-Basic Research Program, NCI-FCRDC,; Frederick, Maryland 21702-1201, USA.
- Human immunodeficiency virus type 1 (HIV-1) mRNAs encoding structural proteins contain multiple inhibitory/instability elements (INS), which decrease the efficiency of viral protein expression. We have previously identified a strong INS element INS-1) within the p17(gag) coding region. Here we show that poly(A)-bindin
- Susceptibility testing of fungi: current status of correlation of in vitro data with clinical outcome.
- J Clin Microbiol. 1996 Mar;34(3):489-95. Unique Identifier : AIDSLINE MED/97060079
- Ghannoum MA; Rex JH; Galgiani JN; Division of Infectious Diseases, Department of Internal Medicine,; Harbor-University of California, Los Angeles, USA. ghannoum@humc.edu
- In summary, it is clear that in vitro susceptibility testing can predict outcome in selected clinical situations. The clearest data are from the fluconazole-treated AIDS patients with oropharyngeal candidiasis. In this setting, the homogeneity of the underlying immune defect, combined with the ease of identification a
- Rapid diagnosis of Mycobacterium tuberculosis bacteremia by PCR.
- J Clin Microbiol. 1996 Mar;34(3):512-5. Unique Identifier : AIDSLINE MED/97060083
- Folgueira L; Delgado R; Palenque E; Aguado JM; Noriega AR; Department of Clinical Microbiology, Hospital Doce de Octubre, Madrid,; Spain.
- A method based on DNA amplification and hybridization has been used for the rapid detection of Mycobacterium tuberculosis in blood samples from 38 hospitalized patients (15 human immunodeficiency virus [HIV] positive and 23 HIV negative) in whom localized or disseminated forms of tuberculosis were suspected. In 32 of
- Quantitative light microscopic detection of Enterocytozoon bieneusi in stool specimens: a longitudinal study of human immunodeficiency virus-infected microsporidiosis patients.
- J Clin Microbiol. 1996 Mar;34(3):520-3. Unique Identifier : AIDSLINE MED/97060085
- Clarridge JE 3rd; Karkhanis S; Rabeneck L; Marino B; Foote LW; Veterans Affairs Medical Center, Baylor College of Medicine, Houston,; Texas 77030, USA.
- The clinical course of microsporidiosis caused by Enterocytozoon bieneusi and the pattern of intestinal shedding of spores have not been co