Aetiological factors for oral manifestations of HIV. NLM AIDSLINE Important note: Information in this article was accurate in 1997. The state of the art may have changed since the publication date.

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Aetiological factors for oral manifestations of HIV.

Oral Dis. 1996 Sep;2(3):193-7. Unique Identifier : AIDSLINE MED/97227796
Palmer GD; Robinson PG; Challacombe SJ; Birnbaum W; Croser D; Erridge PL; Hodgson T; Lewis D; McLaren A; Zakrzewska JM; United Medical School, Guy's Hospital, London, UK.

Abstract: OBJECTIVES: Describe the oral diseases in HIV-infected individuals in London, UK and identify social and medical factors related to the presence of specific oral diseases. DESIGN: Dental clinics. SUBJECTS: Consecutive sample of 456 patients with HIV infection. METHODS: Social and medical history and clinical examinations. Univariate and logistic regression analysis. OUTCOMES: Presence of HIV-associated oral disease. RESULTS: 80% of patients with AIDS and 50% of patients with HIV had a specific oral disease. The most common diseases were hairy leukoplakia 30%), erythematous candidiasis (24%), pseudomembranous candidiasis (14%), angular chielitis (6%), necrotising periodontal disease (8%) and non-recurrent ulceration (6%). CONCLUSIONS: The presence of erythematous candidiasis was not related to advanced HIV disease. Pseudo-membranous candidiasis, hairy leukoplakia and mucosal ulceration were significantly associated with advanced HIV disease. Smoking was also identified as a strong aetiological factor in oral diseases. Longitudinal studies are required to further explore the prognostic significance of oral diseases in HIV infection.
Keywords: *HIV Infections/COMPLICATIONS *Mouth Diseases/ETIOLOGYKWDhivinfections/complicationsKWDmouthdiseases/etiology
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Copyright © 1997 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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