Oral HIV-I recovery in the presence of periodontal disease. NLM AIDSLINE Important note: Information in this article was accurate in 1997. The state of the art may have changed since the publication date.

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Oral HIV-I recovery in the presence of periodontal disease.

Oral Dis. 1996 Sep;2(3):198-201. Unique Identifier : AIDSLINE MED/97227797
Barr CE; Qureshi MN; Qiu Z; Kaim J; Zhang W; Department of Dental Medicine, Beth Israel Medical Center, New York; 10003, USA.

Abstract: OBJECTIVE: To determine whether a significant association occurs between the presence of various periodontal diseases and recoverable infectious HIV-I in the saliva of injecting drug users. DESIGN: Five hundred and fifty-one injecting drug users were recruited from various programs associated with the Beth Israel Medical Center. Examiners were 'blinded' to the subject's HIV-I serostatus. A socio-economic and risk factors' survey was conducted and a complete oral examination, including periodontal disease indices was performed. Whole saliva and blood were collected for virus culture. MAIN OUTCOME MEASUREMENTS: Recovery of infectious HIV-I in saliva related to presence of periodontal diseases. RESULTS: Those HIV-I seropositive subjects with periodontal diseases did not differ from those HIV-I seropositive subjects without periodontal disease in mean age and immune status. Less than 1% of the HIV-I seropositive subjects had cultivable HIV-I in their saliva while it was present in 78% of PBMCs and 35% of the sera. There was no significant association between infectious HIV-I in saliva, serum, or PBMCs and any of the various periodontal diseases. CONCLUSIONS: The presence of periodontal disease in HIV-I seropositive injecting drug users does not appear to be a potential risk factor for infectious HIV-I in saliva, probably due to the various anti-viral components of saliva.
Keywords: *HIV-1/ISOLATION & PURIF *Periodontal Diseases/VIROLOGY *Saliva/VIROLOGYKWDhiv-1/isolation&purifKWDperiodontaldiseases/virologyKWDsaliva/virology
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Copyright © 1997 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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