Secondary immunodeficiencies and stem cell transplantation: issues of administration and safety of intravenous immunoglobulin. NLM AIDSLINE Important note: Information in this article was accurate in 1997. The state of the art may have changed since the publication date.

Click here to return to AIDSLINE main menu
DonateNow
Print this Article


Secondary immunodeficiencies and stem cell transplantation: issues of administration and safety of intravenous immunoglobulin.

Clin Ther. 1996;18 Suppl B:126-36. Unique Identifier : AIDSLINE MED/97084106
Sullivan KM; Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.

Abstract: This article reviews the administration, efficacy, and safety of prophylactic intravenous immunoglobulin in patients with secondary immunodeficiency and those undergoing allogeneic bone marrow transplantation. Associated infections in these immunosuppressed patients are examined as they relate to transfusion-associated transmission, graft-versus-host disease, and other factors. In addition, the safety issues (including infection with cytomegalovirus and hepatitis C virus) involved in hematopoietic stem cell transplant patients given intravenous immunoglobulin are detailed by long-term follow-up of controlled clinical trials.
Keywords: *Bone Marrow Transplantation/ADVERSE EFFECTS *Immunoglobulins, Intravenous/ADVERSE EFFECTS *Immunologic Deficiency Syndromes/THERAPYKWDbonemarrowtransplantation/adverseeffectsKWDimmunoglobulins,intravenous/adverseeffectsKWDimmunologicdeficiencysyndromes/therapy
970630
M9761175

Copyright © 1997 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Bristol-Myers Squibb Company, Elton John AIDS Foundation, Gill Foundation, the National Library of Medicine, Quest Diagnostics, Roche and Trimeris, and donations from users like you. Always watch for outdated information. This article first appeared in 1997. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1997. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .