Microsporidium-associated sinusitis. NLM AIDSLINE Important note: Information in this article was accurate in 1997. The state of the art may have changed since the publication date.

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Microsporidium-associated sinusitis.

Ear Nose Throat J. 1997 Feb;76(2):95-101. Unique Identifier : AIDSLINE MED/97198654
Moss RB; Beaudet LM; Wenig BM; Nelson AM; Firpo A; Punja U; Scott TS; Kaliner MA; Allergic Disease Section, NIAID, NIH, Bethesda, Maryland, USA.

Abstract: Two cases of biopsy-proven Microsporidium-associated chronic sinusitis in HIV-seropositive patients are presented. Spores of Septata intestinalis were identified by light microscopy and confirmed by electron microscopy in each case. Both patients displayed severe deficiencies of nasal mucosa CD4-positive cells, demonstrated by immunohistochemical methods. Only two other cases of Septata intestinalis-associated sinusitis have been reported previously. Our observations agree with the theory that functional defects in local mucosal immunity may partially explain the acquisition of opportunistic mucosal infections in many HIV-seropositive patients.
Keywords: *AIDS-Related Opportunistic Infections/PARASITOLOGY *Microspora Infections/DIAGNOSIS *Microsporida/ISOLATION & PURIF *Sinusitis/PARASITOLOGYKWDaids-relatedopportunisticinfections/parasitologyKWDmicrosporainfections/diagnosisKWDmicrosporida/isolation&purifKWDsinusitis/parasitology
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M9761159

Copyright © 1997 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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