[Report of a case of T-cell peripheral lymphoblastic lymphoma in an HIV patient] NLM AIDSLINE Important note: Information in this article was accurate in 1997. The state of the art may have changed since the publication date.

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[Report of a case of T-cell peripheral lymphoblastic lymphoma in an HIV patient]

An Med Interna. 1996 Sep;13(9):443-6. Unique Identifier : AIDSLINE MED/97122090
Garcia de la Llana F; Mota Vargas R; Rovira Farre I; Pazlasso S; Alejo Pedrero M; Ambrojo P; Unidad Enfermedades Infecciosas, Hospital Regional Universitario; Infanta Cristina, Badajoz.

Abstract: T-cell lymphomas in human immunodeficiency virus infections are rare, first case have being described in 1987, by Presant. Our purpose is to report the first T-cell Lymphoma case without epidermotropism in an HIV patient in Extremadura, and pioneer in Spain. Clinic extensive and histopathologic studies of cutaneous lesions were realized, including monoclonal antibodies tests. Peculiar clinical features were small bowel disease (MALT), gingiva, pericardium and skin involvement, with spontaneous resolution of skin nodules. Polychemotherapy with cyclophosphamide, doxorubicin, vincristine and prednisone was not effective, causing serious myelotoxicity. We outline the rarity of T-cell Lymphomas, the predominance of T4 phenotype, its relation with Epstein-Barr virus, the increase in 6-interleukin production, and the prognostic value of these factors, in correlation with advanced clinical status and unfavorable outcome.
Keywords: *Lymphoma, AIDS-Related/DIAGNOSIS *Lymphoma, Lymphoblastic/DIAGNOSISKWDlymphoma,aids-related/diagnosisKWDlymphoma,lymphoblastic/diagnosis
970730
M9772147

Copyright © 1997 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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