Abstract:
Objective: Determination of HIV-1/2-Seroprevalence, risk factors and clinical features among Surgical and Internal Cases at a Health Station in Western Uganda. Methods: Altogether 243 (162 Trauma- and 81 General/Abdominal-) Surgical outpatients and 671 Internistic in-and outpatients were examined, registered and screened for HIV1/2 by Elisa, followed by confirming Western Blot. Outpatients additionally were tested for syphilis antibodies by treponema pallidum haemagglutinations test. Age ranged among outpatients from 15-69 and among inpatients from 0-69 years, including children. Risk factors like blood transfusions, unstable partnerships, frequent traveling were inquired and statistically evaluated. The main target was to investigate the incidence of HIV-1/2 among different diseases of admission at the health station. Results: Diagnoses with highest incidence of HIV-1 infection were intestinal Kaposi's sarcoma, abdominal TBC and peritonitis in General-and stab- and gun-injuries in Emergency-Surgical Cases. Patients with multimorbidity, diarrhoea, veneral diseases and weakness showed the highest HIV-positivity among Internistic out-and inpatients. HIV-1 seroprevalence in Surgical outpatients was 26,8% (trauma 12,96%, general 54,3%), in internistic outpatients 27,8% and inpatients 44,96%. A Lues/HIV-1-double infection rate of 13,5% was found in outpatients. One confirmed double infection of HIV-1 and-2 was detected. Concerning age ranges seroprevalence of HIV-1 in outpatients reached two peaks, the first at 25-29 (males 20-24) and the second at 40-49 years. Highest HIV-1-incidence among inpatients was found in women at the age of 30-39 and men 40-49. 9,1% of outpatients and 16% of inpatients, of whom 35,4% and 46,8%, respectively, were HIV-1 positve, had got blood transfusions during their lives. Conclusions: We found some Surgical and Internistic features to be more frequent when associated with HIV-infection, higher HIV-1-prevalence in women than men and one confirmed HIV-1/2 double infection in Uganda. A ranking list of diagnoses associated with HIV-infection of this study was drawn.
Keywords: *HIV Infections/EPIDEMIOLOGY *HIV Seroprevalence 970130
M9715973
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