[Changes in the immunocompetent cell system of the peripheral blood in HIV carriage] NLM AIDSLINE Important note: Information in this article was accurate in 1997. The state of the art may have changed since the publication date.

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[Changes in the immunocompetent cell system of the peripheral blood in HIV carriage]

Lik Sprava. 1995 Mar-Apr;(3-4):112-5. Unique Identifier : AIDSLINE MED/96417148
Karabanov VR; Markov IS; Marchenko NE


Abstract: HIV-carriage is characterized by hematological signs such as normocytosis of the general leucocyte count and deviations within normal range of values for myeloid series cells (neutrophiles, eosinophiles, basophiles). A peculiar hematological sign seen in HIV-infection is a finding of a raised content of cellular elements of mononuclear type on a hemogramme of peripheral blood and consistent decrease in the level of small T-lymphocytes against the background of substantial growth of suppressor-killer populations (large lymphocytes and lymphocyte-like mononuclears) as evidenced by a mononucleorogramme of peripheral blood, which fact provide a mechanism of antiviral protection at early stages of HIV-infection. Such changes in hemogrammes of peripheral blood, consistently found in all virus carriers, may be used in clinical settings as an early diagnostic sign of HIV-infection.
Keywords: Carrier State/BLOOD/*DIAGNOSIS English Abstract Female Human HIV Infections/BLOOD/*DIAGNOSIS *HIV-1 Leukocyte Count Leukocytes, Mononuclear/*IMMUNOLOGY Lymphocytes/*IMMUNOLOGY Male JOURNAL ARTICLEKWDcarrierstate/blood/KWDdiagnosisenglishabstractfemalehumanhivinfections/blood/KWDdiagnosisKWDhiv-1leukocytecountleukocytes,mononuclear/KWDimmunologylymphocytes/KWDimmunologymalejournalarticle
970228
M9721915

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