Symmetry-based HIV protease inhibitors containing (S,S) or (R,R) tartaric acid core structure. NLM AIDSLINE Important note: Information in this article was accurate in 1997. The state of the art may have changed since the publication date.

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Symmetry-based HIV protease inhibitors containing (S,S) or (R,R) tartaric acid core structure.

Arzneimittelforschung. 1997 Jul;47(7):889-92. Unique Identifier : AIDSLINE MED/97418245
Marastoni M; Bergonzoni M; Bortolotti F; Tomatis R; Department of Pharmaceutical Science, University of Ferrara, Italy.


Abstract: Two series of symmetry-based HIV protease inhibitors containing S,S) or (R,R) tartaric acid core structure were prepared and tested for inhibitory property against the enzyme. All compounds showed weak antiprotease activity.
Keywords: *HIV Protease Inhibitors/CHEMISTRY *Tartrates/CHEMISTRYKWDhivproteaseinhibitors/chemistryKWDtartrates/chemistry
971230
M97C0654

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