NIAID researchers present new findings at retrovirus meeting. National Institute of Allergy and Infectious Diseases. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply. NLM AIDSLINE Important note: Information in this article was accurate in 1997. The state of the art may have changed since the publication date.

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NIAID researchers present new findings at retrovirus meeting. National Institute of Allergy and Infectious Diseases. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.

NIAID AIDS Agenda. 1997 Mar;:4, 11. Unique Identifier : AIDSLINE AIDS/97702457
Doepel L; Folkers G


Abstract: Research presented at the Third Conference on Retroviruses and Opportunistic Infections included reports on partial restoration of immune function and prolonged survival in people with HIV. Findings from several studies are highlighted. ACTG 315 suggests that potent new drug cocktails may partially restore immune system function. ACTG 193A demonstrates that three antiretrovirals are more effective than two for delaying disease progression and prolonging survival in individuals with advanced HIV disease. Other studies presented new findings on the HIV disease process and the complex interactions between the virus and the human immune system.
Keywords: Anti-HIV Agents/*THERAPEUTIC USE CD4 Lymphocyte Count CD4-Positive T-Lymphocytes/*DRUG EFFECTS Chemokines/*IMMUNOLOGY Clinical Trials Clone Cells Dendritic Cells/IMMUNOLOGY/*VIROLOGY Didanosine/THERAPEUTIC USE Disease Progression Drug Therapy, Combination Female HIV/*DRUG EFFECTS HIV Infections/*DRUG THERAPY/*IMMUNOLOGY HIV Protease Inhibitors/*THERAPEUTIC USE Human Interleukin-10/THERAPEUTIC USE Killer Cells/IMMUNOLOGY Lamivudine/THERAPEUTIC USE Male Pyridines/THERAPEUTIC USE Receptors, Cytokine/IMMUNOLOGY Reverse Transcriptase Inhibitors/*THERAPEUTIC USE Ritonavir/THERAPEUTIC USE Virus Replication/*DRUG EFFECTS Zalcitabine/THERAPEUTIC USE Zidovudine/THERAPEUTIC USE NEWSLETTER ARTICLE MEETING REPORTKWDanti-hivagents/KWDtherapeuticusecd4lymphocytecountcd4-positivet-lymphocytes/KWDdrugeffectschemokines/KWDimmunologyclinicaltrialsclonecellsdendriticcells/immunology/KWDvirologydidanosine/therapeuticusediseaseprogressiondrugtherapy,combinationfemalehiv/KWDdrugeffectshivinfections/KWDdrugtherapy/KWDimmunologyhivproteaseinhibitors/KWDtherapeuticusehumaninterleukin-10/therapeuticusekillercells/immunologylamivudine/therapeuticusemalepyridines/therapeuticusereceptors,cytokine/immunologyreversetranscriptaseinhibitors/KWDtherapeuticuseritonavir/therapeuticusevirusreplication/KWDdrugeffectszalcitabine/therapeuticusezidovudine/therapeuticusenewsletterarticlemeetingreport
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M9781266

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