1996--a very good year for pathogenesis research. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.

Important note: Information in this article was accurate in 1997. The state of the art may have changed since the publication date.

1996--a very good year for pathogenesis research. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.

NIAID AIDS Agenda. 1997 Mar;:8-9. Unique Identifier : AIDSLINE AIDS/97702459
Bowersox J

Abstract: 1996 was a watershed year for AIDS research, largely due to the introduction of protease inhibitors. Researchers also gained crucial new knowledge about the mechanism by which HIV infects CD4 cells, creating an opportunity for deciphering the disease process. Important discoveries made throughout the year by NIAID researchers are briefly described in a chronology of significant findings. Research included a study of individuals who remain HIV-negative in spite of repeated high-risk behavior, the discovery of co-receptors, the role of CCR-5 in protecting against AIDS, and studies on chemokine receptors.

Keywords: CD4-Positive T-Lymphocytes/*IMMUNOLOGY/*VIROLOGY Chemokines/IMMUNOLOGY/*PHYSIOLOGY Disease Progression Female HIV Envelope Protein gp120/IMMUNOLOGY HIV Infections/*GENETICS/*IMMUNOLOGY/*PATHOLOGY Human Male Membrane Proteins/GENETICS/IMMUNOLOGY/*PHYSIOLOGY Mutation Receptors, Cytokine/IMMUNOLOGY Receptors, HIV/PHYSIOLOGY Virus Replication/*IMMUNOLOGY NEWSLETTER ARTICLE
970830
M9781264

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