ACTG 076 and reduction of perinatal transmission. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.

Important note: Information in this article was accurate in 1997. The state of the art may have changed since the publication date.

ACTG 076 and reduction of perinatal transmission. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.

Update/Natl Minor COUNC. 1997 Mar;:4-7, 9. Unique Identifier : AIDSLINE AIDS/97702462

Abstract: ACTG 076 findings demonstrated that a regimen of zidovudine (ZDV) reduced perinatal HIV transmission by two-thirds in infants whose mothers met specific eligibility criteria, including no previous antiretroviral treatment. The study is being hailed as one of the most significant breakthroughs in prevention of HIV, although it did not provide information on the long-term effects of ZDV or any potential adverse effects on the infants involved.

Keywords: Adolescence Adult Animal Anti-HIV Agents/TOXICITY/*THERAPEUTIC USE Blacks CD4 Lymphocyte Count Disease Progression Disease Transmission, Vertical/*PREVENTION & CONTROL HIV Infections/*DRUG THERAPY/EPIDEMIOLOGY/*TRANSMISSION Hispanic Americans Human Infant, Newborn Mandatory Testing/LEGISLATION & JURISPRUD Mice National Institutes of Health (U.S.) Pregnancy Pregnancy Complications, Infectious/*DRUG THERAPY United States/EPIDEMIOLOGY United States Public Health Service Zidovudine/TOXICITY/*THERAPEUTIC USE NEWSLETTER ARTICLE
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M9781261

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