ACTG 320: last of the body count trials? Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.

Important note: Information in this article was accurate in 1997. The state of the art may have changed since the publication date.

ACTG 320: last of the body count trials? Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.

PI Perspect. 1997 Mar;(No 21):7. Unique Identifier : AIDSLINE AIDS/97702495

Abstract: ACTG 320, to no one's surprise, was halted early when results clearly showed two-drug therapy was inferior to a three-drug regimen. Many thought the study was unnecessary because previous studies already concluded that triple combinations were more effective. So-called body count trials, as ACTG 320 was viewed, will no longer be performed if the Food and Drug Administration (FDA) and medical conservatives accept results from earlier trials.

Keywords: Anti-HIV Agents/ADMINISTRATION & DOSAGE/*THERAPEUTIC USE *Clinical Trials Drug Therapy, Combination *Ethics, Medical Female HIV Infections/*DRUG THERAPY HIV Protease Inhibitors/ADMINISTRATION & DOSAGE/THERAPEUTIC USE Human Indinavir/ADMINISTRATION & DOSAGE/THERAPEUTIC USE Lamivudine/ADMINISTRATION & DOSAGE/THERAPEUTIC USE Male Reverse Transcriptase Inhibitors/ADMINISTRATION & DOSAGE/ THERAPEUTIC USE Zidovudine/ADMINISTRATION & DOSAGE/THERAPEUTIC USE NEWSLETTER ARTICLE
970830
M9781254

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