Delavirdine (Rescriptor) approved. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.

Important note: Information in this article was accurate in 1997. The state of the art may have changed since the publication date.

Delavirdine (Rescriptor) approved. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.

AIDS Treat News. 1997 Apr 18;(No 269):1-3. Unique Identifier : AIDSLINE AIDS/97702540
James JS

Abstract: The Food and Drug Administration (FDA) approved delavirdine (Rescriptor) for HIV-1 treatment in March. Delavirdine becomes the second non-nucleoside reverse transcriptase inhibitor approved; the first was nevirapine. The drug must be used in antiretroviral combinations because of resistance problems associated with using it alone. Delavirdine's primary side effect is skin rash, occasionally severe enough to cause permanent discontinuation of the treatment. The approval follows weak clinical data; further clinical testing is called for. Cost is relatively low at $2,250 annually.

Keywords: Anti-HIV Agents/THERAPEUTIC USE Didanosine/THERAPEUTIC USE *Drug Approval *Drug Costs Drug Therapy, Combination HIV Infections/*DRUG THERAPY HIV-1 Human Indoles/ADVERSE EFFECTS/*THERAPEUTIC USE Piperazines/ADVERSE EFFECTS/*THERAPEUTIC USE Reverse Transcriptase Inhibitors/ADVERSE EFFECTS/*THERAPEUTIC USE United States United States Food and Drug Administration Zidovudine/THERAPEUTIC USE NEWSLETTER ARTICLE
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M9781211

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