Dietary consideration and protease inhibitors. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.

Important note: Information in this article was accurate in 1997. The state of the art may have changed since the publication date.

Dietary consideration and protease inhibitors. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.

STEP Perspect. 1996 Fall;8(3):11-4. Unique Identifier : AIDSLINE AIDS/97702553
Lichtenstein BS

Abstract: Protease inhibitor therapy requires that the patient have adequate liver function in order to detoxify the substance before it reaches toxic levels in the bloodstream. Liver functioning is described, as well as the effects of several drugs. Ritonavir, for example, inactivates the cP450 enzyme, which retards the liver's ability to filter out antihistamines and antidepressants, causing life-threatening levels. A healthy diet and avoidance of alcohol and tobacco products can help promote optimum liver functioning. Also, caffeine and cola should be used in limited quantities by those on protease inhibitor therapy.

Keywords: Alcohol Drinking/ADVERSE EFFECTS Cytochrome P-450/DRUG EFFECTS/*METABOLISM HIV Infections/*DIET THERAPY/*DRUG THERAPY HIV Protease Inhibitors/ADVERSE EFFECTS/*METABOLISM Human Hydrocarbons/ADVERSE EFFECTS Liver/*METABOLISM Ritonavir/ADVERSE EFFECTS/*METABOLISM Smoking/ADVERSE EFFECTS NEWSLETTER ARTICLE
970830
M9781198

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