1997

Study confirms that protease inhibitor cocktail can delay HIV disease progression and death. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: NIAID AIDS Agenda. 1997 Mar;:1-2. Unique Identifier : AIDSLINE AIDS/97702455; Randall P; A study funded by the National Institute of Allergy and Infectious Diseases (NIAID) has shown that combination protease inhibitor therapy plus two nucleoside analogues is significantly more effective than using two nucleoside analogs alone in reducing the occurrence of AIDS-defining illnesses and death. Since prelimin
Panel affirms importance of prenatal AZT use. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: NIAID AIDS Agenda. 1997 Mar;:3, 10. Unique Identifier : AIDSLINE AIDS/97702456; Bowersox J; ACTG 076 showed that AZT dramatically reduced the rate of mother-to-child transmission of HIV when administered during pregnancy and childbirth. Researchers concluded that the benefits far outweighed possible increased cancer risks, and emphasized the
NIAID researchers present new findings at retrovirus meeting. National Institute of Allergy and Infectious Diseases. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: NIAID AIDS Agenda. 1997 Mar;:4, 11. Unique Identifier : AIDSLINE AIDS/97702457; Doepel L; Folkers G; Research presented at the Third Conference on Retroviruses and Opportunistic Infections included reports on partial restoration of immune function and prolonged survival in people with HIV. Findings from several studies are highlighted. ACTG 315 suggests that potent new drug cocktails may partially restore immune syst
New vaccine advisory committee endorses innovative grant program. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: NIAID AIDS Agenda. 1997 Mar;:5. Unique Identifier : AIDSLINE AIDS/97702458; Bowersox J; A new grant program from the National Institute of Allergy and Infectious Diseases (NIAID), called the INNOVATION Grant Program for Approaches in HIV Vaccine Research, is designed to speed the pace of work on developing an AIDS vaccine. The first phase of this pilot program encourages three areas of research: understa
1996--a very good year for pathogenesis research. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: NIAID AIDS Agenda. 1997 Mar;:8-9. Unique Identifier : AIDSLINE AIDS/97702459; Bowersox J; 1996 was a watershed year for AIDS research, largely due to the introduction of protease inhibitors . Researchers also gained crucial new knowledge about the mechanism by which HIV infects CD4 cells, creating an opportunity for deciphering the disease process. Import
NIAID funds pediatric AIDS clinical trials group. National Institute of Allergy and Infectious Diseases. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: NIAID AIDS Agenda. 1997 Mar;:12. Unique Identifier : AIDSLINE AIDS/97702460; Doepel L; The National Institute of Allergy and Infectious Diseases (NIAID) has awarded 23 4-year grant programs to the Pediatric AIDS Clinical Trials Group, a national network that coordinates research projects. The money will support 21 trials, a data management center, and a new Coordinating and Operating Center. The restruc
Trends in HIV/AIDS among women of color. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: Update/Natl Minor COUNC. 1997 Mar;:1-4. Unique Identifier : AIDSLINE AIDS/97702461; Maldonado M; The incidence rates of HIV and AIDS among African American and Hispanic women is growing dramatically, and is now the third leading cause of death among women 25 to 44 years old. In developing countries, most women contract HIV from unprotected heterosexual sex; in the U.S., the majority of cases can be traced to inje
ACTG 076 and reduction of perinatal transmission. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: Update/Natl Minor COUNC. 1997 Mar;:4-7, 9. Unique Identifier : AIDSLINE AIDS/97702462; ACTG 076 findings demonstrated that a regimen of zidovudine (ZDV) reduced perinatal HIV transmission by two-thirds in infants whose mothers met specific eligibility criteria, including no previous antiretroviral treatment. The study is being hailed as one of the most significant breakthroughs in prevention of HIV, alt
The influence of hormones and HIV genital transmission in women. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: Update/Natl Minor COUNC. 1997 Mar;:9-11. Unique Identifier : AIDSLINE AIDS/97702463; An animal study with rhesus macaque monkeys showed that those who received subcutaneous progesterone implants were 7.7 times more likely to become infected with SIV. The findings raised strong concerns about two contraceptives on the market that contain progesterone, Depo-Provera and Norplant. The findings are not nec
The drugs we've got...the drugs we're getting...beyond blood. A three-part look at the Fourth Conference on Retroviruses and Opportunistic Infections. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: J Int Assoc Physicians AIDS Care. 1997 Apr;3(4):9-13, 16-8, 21-40. Unique Identifier : AIDSLINE AIDS/97702490; Mascolini M; Some of the most compelling presentations at the Fourth Conference on Retroviruses and Opportunistic Infections were those involving the presence of HIV outside of the blood stream. Other topics discussed included drug-versus-drug studies, antiretroviral therapy for children, and studies showing
Opportunistic infections: stemming the tide. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: J Int Assoc Physicians AIDS Care. 1997 Apr;3(4):42-7. Unique Identifier : AIDSLINE AIDS/97702491; MacDougall DS; Reports from the 1997 Fourth Conference on Retroviruses and Opportunistic Infections reveal encouraging responses to the latest antiretroviral regimens, including using protease inhibitors for treating opportunistic infections. Unfortunately, there appears to be les
A French lesson. French experience shows full funding of treatment advances saves money. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: J Int Assoc Physicians AIDS Care. 1997 Apr;3(4):49. Unique Identifier : AIDSLINE AIDS/97702492; Alcorn K; France s HIV treatment expenditures, the highest in Europe and second only to the United States , have created evidence of the real-life cost-effectiveness of triple combination antiretroviral therapy. The French have demonstrated that savings in treatment costs can be obtained with ear
Themes: the IVth Conference on Human Retroviruses and Opportunistic Infections. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: PI Perspect. 1997 Mar;(No 21):1-4. Unique Identifier : AIDSLINE AIDS/97702493; Presentations at the Fourth Conference on Human Retroviruses and Opportunistic Infections revealed a growing consensus on AIDS research and treatment. The most encouraging aspects of treatment included consistent reductions in viral load, viral load reductions resulting from first-line use of two or more highly active
Viral load and progression. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: PI Perspect. 1997 Mar;(No 21):6-7. Unique Identifier : AIDSLINE AIDS/97702494; Several studies are currently investigating the best ways to use new AIDS drug therapies and handle drug resistance. One study shows that HIV RNA levels in semen strongly correlate with RNA levels in plasma. Other studies report correlations in viral load changes in plasma and lymphoid tissue following combination dru
ACTG 320: last of the body count trials? Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: PI Perspect. 1997 Mar;(No 21):7. Unique Identifier : AIDSLINE AIDS/97702495; ACTG 320, to no one s surprise, was halted early when results clearly showed two-drug therapy was inferior to a three-drug regimen. Many thought the study was unnecessary because previous studies already concluded that triple combinations were more effective. So-called body count trials, as ACTG 320 was viewed, will n
Antiviral update. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: PI Perspect. 1997 Mar;(No 21):8-10. Unique Identifier : AIDSLINE AIDS/97702496; Reports from the 1997 Fourth Conference on Human Retroviruses and Opportunistic Infections continued to present the success of three-drug combinations for the treatment of HIV, and some studies indicate enough restoration of the immune system to sufficiently overcome some opportunistic infections. Updates are provided
AZT during pregnancy. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: PI Perspect. 1997 Mar;(No 21):10. Unique Identifier : AIDSLINE AIDS/97702497; A National Institutes of Health (NIH) independent panel determined that the benefits of HIV-infected pregnant women taking AZT outweigh any risks of AZT leading to cancer in the child. However, the need to counsel HIV-infected pregnant women on the be
Nelfinavir at six months. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: PI Perspect. 1997 Mar;(No 21):11-2. Unique Identifier : AIDSLINE AIDS/97702498; Nelfinavir, the newest protease inhibitor to be approved by the Food and Drug Administration ( FDA ), showed promising preliminary data when it was combined with AZT and
Pediatric update. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: PI Perspect. 1997 Mar;(No 21):12-3. Unique Identifier : AIDSLINE AIDS/97702499; Data is just beginning to emerge concerning protease inhibitor use in children. Studies still require children to take single drugs for long periods, despite the evidence from adult studies showing that prolonged use of these drugs is improper; many children have developed resistance to these drugs. Children, like adu
Glaxo 1592: a call for access, a call for caution. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: PI Perspect. 1997 Mar;(No 21):13-4. Unique Identifier : AIDSLINE AIDS/97702500; Glaxo Wellcome is initiating an expanded access program for its new nucleoside drug, GW1592. It is suggested that, due to Glaxo s problematic drug production, the company make the liquid pediatric formulation for use by adults, make parallel small-scale production lines, o
Protease inhibitors and beyond. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: PI Perspect. 1997 Mar;(No 21):15-6. Unique Identifier : AIDSLINE AIDS/97702501; A new generation of protease inhibitors is entering studies. Abbott Lab s ABT-378 and Pharmacia/Upjohn s PNU-140690 are beginning clinical studies and both are designed to overcome resistance problems. Several companies are developing new compounds to inhibit revers
HIV-related weight loss. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: PI Perspect. 1997 Mar;(No 21):16. Unique Identifier : AIDSLINE AIDS/97702502; Data from a recent study of the testosterone patch do not support its use for treating HIV-related weight loss. Testosterone as a therapy may require higher doses than the body normally produces. Currently, the only approved therapies are megestrol (Megace), dronabinol (Marinol), and recombinant human growth hormone (
IL-2 update. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: PI Perspect. 1997 Mar;(No 21):17. Unique Identifier : AIDSLINE AIDS/97702503; Interleukin-2 has long been researched for treating HIV and has shown the ability to initiate large increases in CD4+ cells in HIV-infected patients; people with more advanced disease have smaller responses. Side effects have been predictable and are sometimes severe. Data suggest the new cells function properly, howe
Medicaid: the system and how to use it. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: PI Perspect. 1997 Mar;(No 21):18-20. Unique Identifier : AIDSLINE AIDS/97702504; Medicaid is a lifeline to HIV care for roughly half of the adults living with AIDS and ninety percent of the children living with AIDS, but it harbors challenges for those who seek to use it. Applying for Medicaid, preparing for the application process, reducing bureaucratic delays, accessing quality care within the c
PHS draft guidelines recommend triple drugs as initial therapy. Public Health Service. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Alert. 1997 May;12(5):49-52. Unique Identifier : AIDSLINE AIDS/97702507; The first government-sanctioned HIV treatment guidelines are being finalized by the National Institutes of Health (NIH) Office of AIDS Research and the National Institute of Allergy and Infectious Diseases (NIAID). The guidelines will replace those developed by the Public Health Service in 1993, before any of the
Disability Act umbrella covers asymptomatic HIV. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Alert. 1997 May;12(5):52-4. Unique Identifier : AIDSLINE AIDS/97702508; A landmark discrimination case was won by an asymptomatic HIV-infected woman whose dentist refused to treat her in his office. He offered to treat her at a hospital, which would have involved much higher costs to her. The decision is controversial; some have criticized it as a civil rights victory that has subverted g
HIV Prevention Act would require HIV reporting. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Alert. 1997 May;12(5):54-5. Unique Identifier : AIDSLINE AIDS/97702509; The HIV Prevention Act of 1997 proposes mandatory, confidential reporting of HIV infection, mandatory partner notification, and a provision that would allow providers to refuse to perform invasive treatment to patients who refuse an HIV test. The bill has been endorsed by the America
Minorities miss out on AIDS survival increase. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Alert. 1997 May;12(5):55-7. Unique Identifier : AIDSLINE AIDS/97702510; AIDS and HIV infection rates are dropping dramatically among white Americans, but African Americans and Hispanics are not benefiting proportionately from treatment advances. Jocelyn Elders, the former U.S. Surgeon General, said that until these communities become more educated about the disease and its prevention, the
After long delays, Hopkins offers AIDS managed care. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Alert. 1997 May;12(5):57-9. Unique Identifier : AIDSLINE AIDS/97702511; Johns Hopkins University s AIDS program is about to offer a capitated rate structure for the State s Medicaid population. Some experts believe that putting Medicaid patients under managed care could be disastrous if rates are capitated. AIDS care, which has recently been seen as part of primary care, is moving back to
Fourth protease inhibitor hits the market. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Alert. 1997 May;12(5):59-60. Unique Identifier : AIDSLINE AIDS/97702512; Nelfinavir ( Viracept ) became the fourth protease inhibitor to gain marketing clearance from the Food and Drug Administration ( FDA ). Approved in mid-March, Viracept will make a contribution to the efforts to treat the
Know these facts about HIV in the `90s. National Minority AIDS Council. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Alert. 1997 May;12(5):suppl 1-2. Unique Identifier : AIDSLINE AIDS/97702513; Recent studies show that HIV is active in an infected person s body from the moment of infection, and it reproduces and spreads very rapidly. Disease mechanisms, viral load, and T-cell counts, are described in laymen s terms. Patients are cautioned about possible problems that will result from noncompliance with the p
Stay healthier longer by fighting infections. National Institutes of Health. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Alert. 1997 May;12(5):suppl 2. Unique Identifier : AIDSLINE AIDS/97702514; HIV infection leaves many patients vulnerable to serious opportunistic infections. Common infections are listed, as well as guidelines for maintaining health. Patients are advised to maintain a healthy lifestyle, obtain regular medical care, and begin prophylactic treatment if so advised by their health care provider.
Time limit applies even if patient is unaware of infection. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Policy Law. 1997 Apr 18;12(7):1, 9. Unique Identifier : AIDSLINE AIDS/97702515; No exception will be made for AIDS in Florida s strict four-year limit for filing medical malpractice claims arising from transfusions and contaminated blood. The State Supreme Court ruled that Francine Damiano, who contracted HIV from a blood transfusion in June 1986 but remained unaware of the contamination until Ap
President selects Thurman to oversee national AIDS policy. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Policy Law. 1997 Apr 18;12(7):1, 10. Unique Identifier : AIDSLINE AIDS/97702516; President Bill Clinton appointed Sandra L. Thurman as the nation s new AIDS policy director. This will be the Clinton administration s third such director in 45 months. Thurman was the executive director of AID Atlanta, and the director of advocacy programs at the Task Force for Child Survival and Development at the C
College aide may be liable for forcing out student with HIV. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Policy Law. 1997 Apr 18;12(7):2. Unique Identifier : AIDSLINE AIDS/97702517; An applicant to Louisiana s Cameron College alleges that the financial aid counselor obstructed her attempt to enter the medical assistant program because she is HIV-positive. Applicant Pansy Griffin claims that counselor Pam Corona insisted that all books and uniforms be paid for in advance, a requirement not imposed
Houston authorizes presentation of HIV videos in city jails. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Policy Law. 1997 Apr 18;12(7):2. Unique Identifier : AIDSLINE AIDS/97702518; The Houston City Council voted to begin showing HIV prevention videos in city jails. The city s Health and Human Services Department determined that inmates need the information but the plan was challenged by critics within the City Council and some citizens of the Houston area. A study found six percent of inmates in
Diner's claim of blood-tainted food is set for appeal. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Policy Law. 1997 Apr 18;12(7):3. Unique Identifier : AIDSLINE AIDS/97702519; Maureen Davis filed suit contending she ate most of a biscuit and gravy from a Hardee s restaurant before realizing it was contaminated with human blood. Davis claims she suffered mental anguish over the possibility of contracting HIV; tests show she is not infected. The Alabama Department of Forensic Science determin
U.S. Supreme Court refuses appeal on union seniority issue. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Policy Law. 1997 Apr 18;12(7):3. Unique Identifier : AIDSLINE AIDS/97702520; The U.S. Supreme Court refused to review an appeal made by a worker who was denied an accommodation for his disability because the union contract awarded jobs based on seniority. The 7th U.S. Circuit Court of Appeals ruling regarding the railroad employee with epilepsy who was warned against working from heights or at
Suit alleges Chicago schools denied job based on HIV. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Policy Law. 1997 Apr 18;12(7):4-5. Unique Identifier : AIDSLINE AIDS/97702521; In 1996, the Lambda Legal Defense and Education Fund persuaded the Chicago Board of Education to revoke a policy that demands applicants to disclose their HIV status. The Board promised to revise the policy, but on March 27, 1997 Lambda filed suit in U.S. District Court against the school board on behalf of an applica
Lack of access to records did not mar fairness of trial. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Policy Law. 1997 Apr 18;12(7):5. Unique Identifier : AIDSLINE AIDS/97702522; The estate of Timothy B. Baker will receive a $75,000 emotional distress award in addition to $104,109 in emotional damages from Dr. Woodruff J. English, II, an infectious disease specialist. Baker suffered an allergic reaction to Cotrim, a sulfa-based medicine prescribed by Dr. English. The reaction resulted in Baker
Police must pay $60,000 for revealing waiter's HIV status. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Policy Law. 1997 Apr 18;12(7):6-7. Unique Identifier : AIDSLINE AIDS/97702523; In Kokomo, IN, an out-of-court settlement of $60,000 was reached in an HIV privacy lawsuit. The case stemmed from a city police officer s demand that a restaurant assign him a new waiter because he did not want to be served by a full-blown AIDS-infested person. The waiter, known in the case as John Doe, lost his job
Court affirms conviction of HIV-positive prostitute. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Policy Law. 1997 Apr 18;12(7):7. Unique Identifier : AIDSLINE AIDS/97702524; The Indiana Court of Appeals ruled that a defendant who was involved in a melee with police can be found guilty of battery by body waste as well as resisting arrest. The appeals court determined that these two charges do not constitute double jeopardy. The case involves Constance Newman, an HIV-positive prostitute who
Tips for starting a peer education program for inmates. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Policy Law. 1997 Apr 18;12(7):8-9. Unique Identifier : AIDSLINE AIDS/97702525; Peer education programs have met with some success in changing HIV risk behaviors in the prison setting. Peer educators effectively communicate with other inmates about how the virus is spread and what can be done to reduce the risk of infection. Properly trained, peer educators may be more credible and relevant with
Center not liable for defamation from false-positive hepatitis test. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Policy Law. 1997 Apr 18;12(7):11. Unique Identifier : AIDSLINE AIDS/97702526; The Nebraska Court of Appeals ruled that Donald R. Helmstadter does not have a cause of action against the Lincoln Plasma Center in Lincoln, NE. The center blacklisted him as a carrier of hepatitis B virus; subsequent tests proved Helmstadter was uninfected. Helmstadter, a paid plasma donator, was placed on an ineligi
Fewer AIDS deaths and illnesses: new information. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Treat News. 1997 Feb 21;(No 265):1-3. Unique Identifier : AIDSLINE AIDS/97702527; James JS; AIDS death rates have fallen to about half of the previous levels among those who have access to new treatment options. Information on survival and hospitalization rates presented at the recent retroviruses conference is summarized. The 48 percent decline in New York City rates for AIDS deaths is attributed to more te
Nelfinavir - major trial results at retroviruses conference. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Treat News. 1997 Feb 21;(No 265):3-4. Unique Identifier : AIDSLINE AIDS/97702528; Nelfinavir ( Viracept ) is expected to be approved soon by the Food and Drug Administration ( FDA ). This fourth protease inhibitor appears to have fewer side effects, a different resistance profile, and offers new option
Danger: possibly fatal interactions between ritonavir and "ecstasy," some other psychoactive drugs. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Treat News. 1997 Feb 21;(No 265):5. Unique Identifier : AIDSLINE AIDS/97702529; Mirken B; Following the death of a British AIDS patient who was taking the protease inhibitor ritonavir when he died of an overdose of MDMA, or ecstasy, ritonavir producer Abbott Laboratories has acknowledged potentially da
Free viral load tests becoming available for uninsured patients. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Treat News. 1997 Feb 21;(No 265):5-6. Unique Identifier : AIDSLINE AIDS/97702530; Viral load test manufacturers have started two programs to make the tests available to those who cannot pay for them. To qualify, patients must be HIV-positive, have a doctor order the test, and not be able to have the costs covered through their insurance. Both PCR (polymerase chain reaction, by
ABT-378: Abbott "second generation" protease inhibitor. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Treat News. 1997 Feb 21;(No 265):6. Unique Identifier : AIDSLINE AIDS/97702531; James JS; Abbott Laboratories has released the first public data on ABT-378, a new generation protease inhibitor that is designed to be effective even against protease inhibitor-resistant HIV. ABT-378 is active against viruses that are resistant to
Drug-related neuropathy: low acetylcarnitine levels found. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Treat News. 1997 Feb 21;(No 265):6-7. Unique Identifier : AIDSLINE AIDS/97702532; James JS; Persons with peripheral neuropathy induced by ddI, ddC , or d4T were found to have low levels of acetylcarnitine in their blood. The
Stanford NAC study: glutathione level predicts survival. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Treat News. 1997 Mar 7;(No 266):1-5. Unique Identifier : AIDSLINE AIDS/97702533; James JS; CD4 cells with low levels of glutathione, a biochemical that protects cells from oxidative stress, have been found to be predictive of poor survival. A randomized study of N-acetyl-cysteine, a drug that helps replenish glutathione, began with in-depth analysis of glutathione levels in different lymphocyte subsets, and
AIDS survival: first drop in total deaths in U.S.; larger drop in France. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Treat News. 1997 Mar 7;(No 266):1, 6-7. Unique Identifier : AIDSLINE AIDS/97702534; James JS; In February 1997, the U.S. Centers for Disease Control and Prevention (CDC) reported a 12 percent decline in AIDS deaths over a 1-year period, the first drop in total deaths from AIDS in the United States . The decline was greatest in the West and Northeast, followed by the Midwest and
Protease inhibitors: major study stopped when 3-drug arm proves superior. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Treat News. 1997 Mar 7;(No 266):7-8. Unique Identifier : AIDSLINE AIDS/97702535; ACTG 320, a clinical trial comparing indinavir / AZT / 3TC to AZT/3TC was stopped early when it became clear that the 3
San Francisco: cattle grazing, reservoirs, and cryptosporidiosis. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Treat News. 1997 Mar 7;(No 266):8. Unique Identifier : AIDSLINE AIDS/97702536; Sabados R; The San Francisco Public Utilities Commission is considering no longer allowing cattle to graze in watershed areas. Since 40-60 percent of cattle in the area are infected with cryptosporidia, they are considered a source of the disease when their feces, containing the parasite, runs off into the water supply. A vote w
Nelfinavir (Viracept) approved: fourth protease inhibitor available. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Treat News. 1997 Mar 21;(No 267):1-2. Unique Identifier : AIDSLINE AIDS/97702537; James JS; The Food and Drug Administration ( FDA ) approved nelfinavir ( Viracept ) for both adult and pediatric use for treatment of HIV infection when antiretroviral therapy is warranted. The drug is the fourth protease inhibitor
It's time to approve more surrogate markers. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Treat News. 1997 Mar 21;(No 267):3-4. Unique Identifier : AIDSLINE AIDS/97702538; Scondras D; Advances in AIDS treatments have led to nationwide declines in AIDS-related deaths, but the development of new therapies must continue. Because accepted markers for improved immune function are lacking, the further development of new therapies is stalled. Neither of the markers that are currently accepted, CD4 T-cell
AIDS treatment activism: focus on service. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Treat News. 1997 Mar 21;(No 267):4-8. Unique Identifier : AIDSLINE AIDS/97702539; James JS; To coincide with the tenth anniversary of ACT UP, the effectiveness of the AIDS treatment movement is assessed. Activists have been instrumental in sensitizing the medical community to the needs of patients, pressuring drug companies to develop programs to make treatments financially accessible, and establishing stand
Delavirdine (Rescriptor) approved. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Treat News. 1997 Apr 18;(No 269):1-3. Unique Identifier : AIDSLINE AIDS/97702540; James JS; The Food and Drug Administration ( FDA ) approved delavirdine ( Rescriptor ) for HIV-1 treatment in March. Delavirdine becomes the second non-nucleoside
Nelfinavir combination therapy: ten-month report. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Treat News. 1997 Apr 18;(No 269):3. Unique Identifier : AIDSLINE AIDS/97702541; Results of studies of a triple combination of nelfinavir, AZT , and 3TC were reported at the Fourth Conference on Retroviruses and Opportunistic Infections and at the International Con
PMPA--first human results. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Treat News. 1997 Apr 18;(No 269):3, 6. Unique Identifier : AIDSLINE AIDS/97702542; James JS; Gilead Sciences new antiretroviral, PMPA, has shown exceptional activity in some animal tests. Results of the first human trial show viral load reductions of 1.1 log after one week, theoretically the most possible decline after one week of treatment. Animal trials with SIV have shown a two to three log viral reductio
Standard treatments for HIV, Spring 1997. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Treat News. 1997 Apr 18;(No 269):4-5. Unique Identifier : AIDSLINE AIDS/97702543; Smith D; Current treatment standards dictate combination anti-HIV therapy. A brief guide to antiretroviral drugs, including reverse transcriptase inhibitors, non-nucleoside reverse transcriptase inhibitors, and protease inhibitors that are approved by the Food and Drug Admin
Medical marijuana wins temporary restraining order. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: AIDS Treat News. 1997 Apr 18;(No 269):7. Unique Identifier : AIDSLINE AIDS/97702544; Tobias T; A Federal judge in San Francisco has issued a temporary restraining order barring Federal officials from prosecuting physicians who recommend marijuana for medicinal purposes. The restraining order is temporary, and a settlement conference is scheduled for April 17, 1997. In the meantime, physicians can discuss uses o
Psychoneuroimmunology: a basis for HIV treatment. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: Focus. 1997 Feb;12(3):1-4. Unique Identifier : AIDSLINE AIDS/97702545; Leiphart JM; Lesbian and Gay Men's Center of San Diego, Lesbian and Gay Men's; Community Center, San Diego, CA.; Psychoneuroimmunology (PNI), the study of the impact of psychological factors on immunological diseases, has been studied in relation to AIDS in a flurry of research over the past 10 years. PNI research has shown that some psychological states lead to AIDS progression, while others improve immunity and survival. Some
Clearinghouse: PNI and AIDS. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: Focus. 1997 Feb;12(3):4-5. Unique Identifier : AIDSLINE AIDS/97702546; A bibliography of materials on psychoneuroimmunology (PNI) and AIDS is provided. The names and addresses of leading PNI researchers in Los Angeles, Miami, San Diego, and Boston are listed.
The biological basis for psychoneuroimmunology. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: Focus. 1997 Feb;12(3):5-6. Unique Identifier : AIDSLINE AIDS/97702547; Cole SW; University of California Los Angeles, School of Medicine, Los; Angeles, CA.; The brain and the immune system are linked by two major physiologic systems: the sympathetic nervous system (SNS) and the hypothalamic-pituitary-adrenal system (HPA). The effect of these systems on the immune system is related to HIV disease and HIV-related care. The SNS and the HPA both play roles in normal body func
A STEP summary of the XIth International AIDS Conference. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: STEP Perspect. 1996 Summer;8(2):1-10. Unique Identifier : AIDSLINE AIDS/97702548; Schouten JT; Issues presented at the International AIDS Conference included basic science, treatments, and social service needs of people with HIV. Topics highlighted include global epidemiology issues, the impact of AIDS on women, viral dynamics, viral load and resistance, immunologic factors, therapy guidelines and approved medi
Nutrition power not an alternative. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: STEP Perspect. 1996 Summer;8(2):12-3. Unique Identifier : AIDSLINE AIDS/97702549; Jensen J; Health and Nutrition Awareness, Santa Monica, CA.; Some nutritional therapy is considered alternative or experimental, but basic good nutrition is essential to effectively combat HIV. The gastrointestinal tract is susceptible to a variety of opportunistic infections. Common medical problems of the gastrointestinal system are listed, and patients are advised to choose
Evaluating treatment options and health care providers: strategies for self-advocacy. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: STEP Perspect. 1996 Fall;8(3):1-4. Unique Identifier : AIDSLINE AIDS/97702550; Shouten J; Hubert J; Coppedge B; HIV treatment has become so effective that people are beginning to speak of eradicating the disease. However, patients need to become thoroughly informed about treatment options in order to ensure that they are getting the best care available. Patients generally do better if their physician is experienced in dealing w
Recent development in the treatment and prevention of disseminated Mycobacterium avium complex (MAC). Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: STEP Perspect. 1996 Fall;8(3):5-6. Unique Identifier : AIDSLINE AIDS/97702551; Schouten JT; Whittemore S; Disseminated Mycobacterium avium complex (DMAC) is the third most common opportunistic infection in people with AIDS, infecting up to 50 percent of them. Symptoms include high fever, weight loss, fatigue, diarrhea, poor appetite, night sweats, and anemia. Diagnosis is by blood culture. Results of two recent studies ar
New recommendations on health care worker exposure to HIV. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: STEP Perspect. 1996 Fall;8(3):8-10. Unique Identifier : AIDSLINE AIDS/97702552; Woodward J; University of Washington, Seattle, WA.; Health care workers who deal with HIV patients are trained and knowledgeable in universal precautions. However, they remain at risk of seroconversion from accidental exposure, and new treatment options are highlighted. Theories on viral dynamics and aggressive antiretroviral regimens suggest that health care workers r
Dietary consideration and protease inhibitors. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: STEP Perspect. 1996 Fall;8(3):11-4. Unique Identifier : AIDSLINE AIDS/97702553; Lichtenstein BS; Protease inhibitor therapy requires that the patient have adequate liver function in order to detoxify the substance before it reaches toxic levels in the bloodstream. Liver functioning is described, as well as the effects of several drugs. Ritonavir ,
ICAAC update. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: STEP Perspect. 1996 Fall;8(3):15-6. Unique Identifier : AIDSLINE AIDS/97702554; Coppedge B; Research topics presented at the 36th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) are highlighted. Topics include the clinical benefits of 3TC (lamivudine), combination
Depression & HIV: assessment and treatment. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: STEP Perspect. 1997 Winter;9(1):1-5. Unique Identifier : AIDSLINE AIDS/97702555; Elliott A; University of Washington, Madison Clinic, Seattle, WA.; Although the advent of protease inhibitors has greatly extended the life expectancy of those living with HIV, they also have introduced the problems of emotionally dealing with a chronic illness. Depression appears to be the most common psychiatric disorder found am
Food, fitness and HIV: the connection. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: STEP Perspect. 1997 Winter;9(1):6, 8. Unique Identifier : AIDSLINE AIDS/97702556; Beesley S; Maurice J; Chicken Soup Brigade, Seattle, WA.; An HIV-positive diagnosis is often followed by wasting syndrome, in which chronic loss of muscle makes the patient feel progressively weaker and sicker. Exercise and eating can minimize muscle loss. Patients are advised to eat small frequent meals with high calorie and high protein foods. They should also eat at least
Immune modulation with IL-2 and IL-12. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: STEP Perspect. 1997 Winter;9(1):9-12. Unique Identifier : AIDSLINE AIDS/97702557; Boonprakong L; University of Washington, School of Medicine, AIDS Clinical; Trials Unit, Seattle, WA.; Scientists have identified a number of chemical messengers that play a fundamental role in directing the body s natural response to the invasion of organisms and pathogens in the human immune system. One group, cytokines, are an essential communications link between the cells of the immune system and the body. The dec
AIDS survival progress. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: STEP Perspect. 1997 Winter;9(1):15-6. Unique Identifier : AIDSLINE AIDS/97702558; Fowler K; Much of the good news in AIDS treatment is buried in medical literature that is technical and difficult to read. This overview of current research in progress describes the positive findings of several studies. One study shows that only 55 percent of those diagnosed in 1983 survived for a year, while 90 percent diagno
List of studies - Spring 1997. University of Washington AIDS Clinical Trials Unit. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: STEP Perspect. 1997 Winter;9(1):17-8. Unique Identifier : AIDSLINE AIDS/97702559; A chart listing current studies that are open for enrollment at the University of Washington in Spring 1997 is provided. The diseases being studied, the treatments involved, the length of the study, and a short description of each trial are given.
Opportunistic disease and other condition studies open for enrollment--August 1996. University of Washington AIDS Clinical Trials Unit. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: STEP Perspect. 1996 Summer;8(2):18-9. Unique Identifier : AIDSLINE AIDS/97702560; A chart listing the current studies that are open for enrollment at the University of Washington in August 1996 is provided. The diseases being studied, the treatments involved, the length of study, and a short description of each trial are given.
List of studies - October 1996. University of Washington AIDS Clinical Trials Unit. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: STEP Perspect. 1996 Fall;8(3):17-8. Unique Identifier : AIDSLINE AIDS/97702561; A chart listing current studies that are open for enrollment at the University of Washington in October 1996 is provided. The diseases being studied, the treatments involved, the length of study, and a short description of each trial are given.
Some relief from the epidemic. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: GMHC Treat Issues. 1997 Mar;11(3):1-3. Unique Identifier : AIDSLINE AIDS/97702562; Cadman JA; Death and hospitalization rates for people with AIDS dropped sharply in 1996, due to prevention of opportunistic infections, better medical care, and combination antiretroviral therapy. The Centers for Disease Control and Prevention (CDC) announced that this was the first decline since the epidemic was identified. Res
Spring cleaning in trial land. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: GMHC Treat Issues. 1997 Mar;11(3):4-7. Unique Identifier : AIDSLINE AIDS/97702563; Gilden D; Several clinical trials have been shut down earlier than planned, following the striking results shown in the trials. ACTG 320, studying whether an AZT / 3TC combination was more effect
A NAC for controversy. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: GMHC Treat Issues. 1997 Mar;11(3):7, 10-2. Unique Identifier : AIDSLINE AIDS/97702564; Gilden D; Cadman J; NAC (N-acetylcysteine) is a compound essential for the synthesis of glutathione, a cellular antioxidant. Administration of NAC is useful in prolonging survival, and people with HIV should avoid behaviors such as chronic use of alcohol or acetaminophen (Tylenol) that deplete glutathione. Glutathione is a key compound f
FDA approves nelfinavir. Food and Drug Administration. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: GMHC Treat Issues. 1997 Mar;11(3):8. Unique Identifier : AIDSLINE AIDS/97702565; The Food and Drug Administration ( FDA ) approved Agouron Pharmaceutical s new protease inhibitor, nelfinavir, in March. Nelfinavir received clearance for distribution through the agency s accelerated approval procedure, and is the first of its class
More pharmacies to carry Crixivan. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: GMHC Treat Issues. 1997 Mar;11(3):8-9. Unique Identifier : AIDSLINE AIDS/97702566; Access to indinavir ( Crixivan ) has been severely limited by production problems since it entered the market in March of 1996, and access has only been through the mail-order Stadtland
Viral load patient assistance programs. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: GMHC Treat Issues. 1997 Mar;11(3):9. Unique Identifier : AIDSLINE AIDS/97702567; Chiron and Roche have set up patient assistance programs to insure access to their viral load tests for patients who cannot pay for them. Roche s program involves sending an applicant s doctor a voucher for a free test, which is performed within two weeks at a participating lab. Eligible patients can receive a maximum
New ways to treat HIV. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: Treat Rev. 1996 Dec;(No 23):2-3. Unique Identifier : AIDSLINE AIDS/97702568; Recent scientific breakthroughs have completely changed the treatment of HIV. Reducing HIV levels seems to slow the progression of the disease and to give the immune system a chance to recover, and aggressive early treatment is the norm. Viral load testing is used to measure the effectiveness of treatment regimens, an
Combination treatment -- study results. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: Treat Rev. 1996 Dec;(No 23):4-11. Unique Identifier : AIDSLINE AIDS/97702569; Research studies show that combinations of anti-HIV drugs work considerably better than any of them given alone, and have even been shown to reduce the level of HIV in the blood to undetectable levels. This overview examines all the current pharmaceuticals on the market, in combinations frequently prescribed. Side eff
Zinc finger inhibitor for HIV. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: Treat Rev. 1996 Dec;(No 23):13. Unique Identifier : AIDSLINE AIDS/97702570; Zinc finger inhibitors are a class of anti-HIV drugs currently under development and entering clinical trials. The drugs block a part of HIV known as zinc fingers, which help assemble new viruses as they leave an infected cell. Blocking zinc fingers means that HIV makes copies of itself that do not work and cannot inf
Three drug combo halves AIDS deaths. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: Treat Rev. 1997 Apr;(No 24):2-4. Unique Identifier : AIDSLINE AIDS/97702571; Although a safety review board stopped ACTG 320 before its completion, the study showed that a three-drug combination could cut the mortality rate from AIDS in half. Study participants who were taking two nucleoside analog drugs were also given a protease inhibitor, and they developed half as many opportunistic infect
New drug approved to treat HIV. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: Treat Rev. 1997 Apr;(No 24):5. Unique Identifier : AIDSLINE AIDS/97702572; Nelfinavir ( Viracept ) was approved in March 1997 by the Food and Drug Administration ( FDA ) as the fourth commercially-available protease inhibitor. It, like the others, is most effective in combination with two nucleo
Saquinavir switch study stopped. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: Treat Rev. 1997 Apr;(No 24):6. Unique Identifier : AIDSLINE AIDS/97702573; ACTG 333 has been discontinued. Early test results showed that people who took the hard-gel version of saquinavir received no benefit from switching to a new saquinavir formulation, or to indinavir . This suggests that patients who take saquinavir as t
Hand and foot pain study. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: Treat Rev. 1997 Apr;(No 24):6. Unique Identifier : AIDSLINE AIDS/97702574; A new clinical trial is studying the drug nerve growth factor as a potential treatment for HIV-related neuropathy that results from HIV-induced damage to nerve endings. The nerve damage often causes pain in the feet and the hands. Nerve growth factor may be the first treatment to repair damage to nerves. Patients on c
Advanced AIDS treatment. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: Treat Rev. 1997 Apr;(No 24):7. Unique Identifier : AIDSLINE AIDS/97702575; A trial has been started to study granulocyte-macrophage colony-stimulating factor (GM-CSF) in people with AIDS. This drug may help people to produce additional infection-fighting white blood cells. Participants need to be on approved HIV drugs. The test will involve shots injected under the skin three times a week; h
Ecstasy and ritonavir. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: Treat Rev. 1997 Apr;(No 24):7. Unique Identifier : AIDSLINE AIDS/97702576; The combination of ritonavir and the illegal drug MDMA (street name ecstasy) may be fatal. People taking both drugs had a two to three fold increase in ecstasy levels in the blood. There may be similar problems with patients on methadone.
[New drugs, new obstacles in the fight against HIV] Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: Sidahora. 1996 Aug/Sep;:13-4. Unique Identifier : AIDSLINE AIDS/97702577; Fonseca MS; Panos Institute, Washington, DC. panos@cais.com.; Treatment with protease inhibitors , drugs that inhibit HIV protease, an essential enzyme for the survival of the HIV virus, decreases HIV to undetectable levels and has generated great optimism. Although far from finding a cure, these findings are steps toward under
[Surviving AIDS in prison: autonomy and self-empowerment] Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: Sidahora. 1996 Aug/Sep;:15-6. Unique Identifier : AIDSLINE AIDS/97702578; Vasquez D; Gomez E; Living with HIV in prison is not a pleasant experience, especially without the tools to survive. It is public knowledge that the Correctional Department is indifferent toward inmates with AIDS. Educational information for prisoners living with HIV to learn as much as possible about AIDS and their rights is provided. M
[Awilda Gonzalez, working in AIDS inside and outside of prison] Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: Sidahora. 1996 Aug/Sep;:17-8. Unique Identifier : AIDSLINE AIDS/97702579; Awilda Gonzalez discusses her experiences working with incarcerated people living with AIDS. Awilda has worked as a counselor for Housing Works, an organization that provides housing and other services for people with AIDS. Awilda also worked at the Bedford Hills correctional facility. As an inmate, she helped to star
[ABC of the antivirals] Project Inform. Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: Sidahora. 1996 Aug/Sep;:19-32. Unique Identifier : AIDSLINE AIDS/97702580; Scientists have tried to inhibit or slow down the HIV virus ever since the virus was identified as the cause of AIDS. Although the efforts have not produced a long-term solution, significant progress has been made. There is a correlation between the increase in HIV levels and the advanced state of the disease. Antivir
[What is the correct way to use protease inhibitors?] Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: Sidahora. 1996 Aug/Sep;:33-5. Unique Identifier : AIDSLINE AIDS/97702581; Agosto M; National Minority AIDS Council, Washington, DC.; Anyone infected with the HIV virus who is considering treatment should have as much information as possible about the different options available. To treat the infection, doctors are using antiretrovirals to slow down the production of the virus inside the body. Some of the issues that have to be addressed include ava
[Anal cancer] Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: Sidahora. 1996 Aug/Sep;:36-7. Unique Identifier : AIDSLINE AIDS/97702582; Majchrowicz M; Gomez E; AIDS Project Los Angeles, Los Angeles, CA.; Kaposi s sarcoma and cervical cancer are the most common AIDS-related cancers. Anal cancer, affecting both men and women, has largely been ignored. Since many diseases can occur around the anal area, there are not definitive symptoms to diagnose any abnormal growths. Studies have shown that people living with HIV suff
[Bilingual education program on HIV/AIDS treatment] Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: Sidahora. 1996 Aug/Sep;:38. Unique Identifier : AIDSLINE AIDS/97702583; Latino Commission on AIDS, New York, NY.; The Bilingual Education Program on HIV/AIDS Treatment educates individuals who live, work, and are affected by HIV/AIDS to develop their abilities as leaders and promoters of information on the treatment of HIV/AIDS. The program includes an overview of HIV/AIDS, treatments, and ways to access information and programs.
[Fraud and opportunism in Honduras] Clearinghouse, AIDS Newsletter Database, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5714. A fee will apply.: Sidahora. 1996 Aug/Sep;:39-40. Unique Identifier : AIDSLINE AIDS/97702584; Santana C; Catherine Quinn, a nurse from Chicago, works with people living with AIDS in Honduras . Catherine discusses the people who take advantage of the sick and poor for economic reasons. She recalls how people in Honduras were taken advant
An autocrine growth mechanism in retroperitoneal fibromatosis, a model for AIDS related Kaposi's sarcoma.: Diss Abstr Int [B]; 56(8):4107 1995. Unique Identifier : AIDSLINE ICDB/97619959; Woon M; Saint Louis Univ.; The human acquired immune deficiency syndrome (AIDS) is a global epidemic disease first recognized in 1981. Affected individuals develop severe impairment of both cellular and humoral immune functions with a variety of opportunistic infections and are susceptible to neoplastic developments such as Kaposi s sarcoma (KS
Escape from transforming growth factor-beta-mediated growth regulation in Epstein-Barr virus-positive or AIDS-associated transformed B cells.: Diss Abstr Int [B]; 56(8):4225 1995. Unique Identifier : AIDSLINE ICDB/97619996; Arvanitakis L; Brown Univ.; Transforming growth factor-beta (TGF-beta) is a member of a family of multifunctional growth factors regulating cell proliferation and differentiation. Generally, TGF-beta inhibits proliferation and has been shown to be an important regulator of immune responses. Here we show that TGF-beta1 induces growth arrest, but
Evaluation of lithium gamma-linolenate (EF-13), a novel antiviral and anti-neoplastic compound (Meeting abstract).: Can J Infect; 6(Suppl C):298C 1995. Unique Identifier : AIDSLINE ICDB/97624598; Conway B; Mpanju O; Randall S; Winther M; Univ. of British Columbia, Vancouver, British Columbia, Canada; Conventional approaches to antiviral therapy are based on the development of compounds that inhibit viral replication directly. EF-13, the lithium salt of the polyunsaturated fatty acid gamma linolenic acid (GLA), appears to have an indirect action against viral replication. GLA is reported to have differential cytoto
Interaction of the MAIDS defective virus with its host (Meeting abstract).: Leukemia and Lymphoma, Pathogenesis and Treatment, Molecular Aspects, p. 28. 18th Symposium of the International Association for Competitive Research on Leukemia and Related Diseases, Kyoto, Japan, October 29-November 3, 1995.. Unique Identifier : AIDSLINE ICDB/97625254; Jolicoeur P; Clinical Research Institute of Montreal, Montreal, H2W 1R7,; Canada; The murine AIDS (MAIDS) is a severe immune disease induced by a defective murine leukemia virus which codes for a single gene product, Pr60gag. Mutational analysis has revealed th Pr60gag is necessary and sufficient to induce disease and that is must be myristylated at its N-terminus. Peripheral mature B cells are the
Models of HTLV-I-induced diseases: infectious transmission of HTLV-I in inbred rats and HTLV-I env-pX transgenic rats (Meeting abstract).: Leukemia and Lymphoma, Pathogenesis and Treatment, Molecular Aspects, p. 32. 18th Symposium of the International Association for Competitive Research on Leukemia and Related Diseases, Kyoto, Japan, October 29-November 3, 1995.. Unique Identifier : AIDSLINE ICDB/97625260; Yoshiki T; Department of Pathology, Hokkaido Univ. Sch. Med., Sapporo 060,; Japan; To examine the pathogenic roles of HTLV-I in HTLV-I-induced diseases, we developed two models: namely HTLV-I carrier rats and HTLV-I env-pX transgenic rats. Among life long HTLV-I carriers in seven rat strains, only WKAH rats with the RT1k haplotype developed chronic progressive myeloneuropathy, resembling HAM/TSP cli
Immunotherapy with tumor vaccines in renal cancer (Meeting abstract).: Ann Oncol; 7(Suppl 1):18 1996. Unique Identifier : AIDSLINE ICDB/97625860; Pardoll DM; John Hopkins University School of Medicine, Baltimore, MD; There is mounting evidence that many if not all tumors possess antigens capable of being recognized by T cells. Over the past few years, our group has been analyzing the immune response induced by immunization with tumors engineered to secrete cytokines locally. In a study comparing multiple different cytokine genes,
Seminars in medicine of the Beth Israel Hospital, Boston. Pathogenesis of diseases induced by human lymphotropic virus type I infection: N Engl J Med; 328(16):1173-82 1993. Unique Identifier : AIDSLINE ICDB/97627321; Hollsberg P; Hafler DA; Department of Medicine, Brigham and Women's Hospital, Boston, MA; Human lymphotropic virus type I (HTLV-I), which has been associated with human disease only since the early 1980s, is a typical retrovirus with gag, pol, and env regions in its gene, but also has a unique pX region at the 3 end. Its epidemiology came under intensive study when tropical spastic paraparesis, T-cell leu
Management of fever in patients with cancer and treatment-induced neutropenia: N Engl J Med; 328(18):1323-32 1993. Unique Identifier : AIDSLINE ICDB/97627338; Pizzo PA; Pediatric Branch, National Cancer Institute, Bethesda, MD 20892; It is more than 30 years since the major role of neutropenia in the risk serious infections in cancer patients receiving chemotherapy was first recognized; such risks extend to other immunosuppressed patients such as those with AIDS or undergoing transplantation. Successful management of fever and neutropenia has dras
HIV risk among low-income African American mothers of elementary school children.: J Health Soc Policy. 1997;8(3):27-39. Unique Identifier : AIDSLINE AHA/97278789; Cummings GL; Battle R; Barker J; Krasnovsky F; Department of Epidemiology and Biostatistics, University of; California, San Francisco, USA.; Data from 119 African American low-income mothers of school aged children in Oakland, California show that 38% engaged in behavior that might place them at risk of exposure to the human immunodeficiency virus (HIV). Risk behaviors that were investigated included having multiple partners and having a partner with an in
Correlates of child care providers' interpretation of pediatric AIDS: implications for education and training.: Health Educ Res. 1997 Mar;12(1):53-60. Unique Identifier : AIDSLINE HTA/97267373; Coleman M; University of Georgia, Athens 30602, USA.; A total of 212 child care providers residing in a southeastern state were surveyed about their knowledge and attitudes toward AIDS and child care policies. Providers feeling about caring for an HIV-infected child, rather than their perceived knowledge of AIDS, were most consistently correlated with their factual know
Practice brief. Issue: Managing health information relating to infection with the human immunodeficiency virus (HIV). American Health Information Management Association.: J AHIMA. 1997 Feb;68(2):1 p. following 44. Unique Identifier : AIDSLINE AHA/97299566
Where all care is home care: HIV/AIDS in Thailand.: Caring. 1997 Apr;16(4):42-5. Unique Identifier : AIDSLINE AHA/97305739; Sacks RG; Population and Community Development Association, Bangkok,; Thailand.; In Thailand the concept of professional home care services does not exist in either the language or the culture. Virtually all health care, including care of people with HIV/AIDS, is provided by family caregivers in the home.
Bringing calm to the storm.: Mich Health Hosp. 1997 May-Jun;33(3):39. Unique Identifier : AIDSLINE AHA/97320332; Majors MC
OSHA issues hepatitis B disinfectant policy.: Exec Housekeep Today. 1997 May;18(5):9-10. Unique Identifier : AIDSLINE AHA/97294270; Goodman G; Marketing Counselors International, Inc., Santa Fe, NM 87504,; USA.
Une mort africaine : le sida au quotidien.: Paris : Editions du seuil, c1995 230 p. : ill (L'histoire immediate) Unique Identifier : AIDSLINE CAT/9703402; Prolongeau H
La prigione malata : letture in tema di AIDS, carcere e salute.: Torino : L'Harmattan Italia, c1996 232 p (Diritto, devianza e societa) Unique Identifier : AIDSLINE CAT/9702399; Magliona B
AIDS-SprechStunde : ein medizinisch-therapeutischer Ratgeber.: Stuttgart : Urachhaus, c1996 336 p. : ill (SprechStunde) Unique Identifier : AIDSLINE CAT/9701919; Straube M
Des infirmieres face au SIDA : representations et conduites, permanence et changements.: Paris : Editions INSERM, c1994 265 p (Analyses et prospective) Unique Identifier : AIDSLINE CAT/9502648; Giami A
Psycho-social and cultural aspects of AIDS.: Bern : Swiss National Foundation for Scientific Research, 1994 48 p Unique Identifier : AIDSLINE CAT/9705241; Hausser D
Sida et infection par le VIH. 3. ed. rev. et augm.: Paris : Masson, c1996 xiv, 288 p. : ill (Abreges) Unique Identifier : AIDSLINE CAT/9703228; Cassuto J
Virus Load und AIDS : Bedeutung der Virusbelastung fur die Therapie der HIV-Erkrankung.: Stuttgart ; New York : Georg Thieme Verlag, 1997 ix, 165 p. : ill (HIV-Medizin. Standards of Care) Unique Identifier : AIDSLINE CAT/9702695; Jager H
AIDS in U.S. hospitals, 1986-1987 : a national perspective.: Rockville, Md. : U.S. Dept. of Health and Human Services, Public Health Service, Agency for Health Care Policy and Research, Center for General Health Services Intramural Research, [1991] 21 p. : ill (Research note / Hopsital Studies Program ; 15) Unique Identifier : AIDSLINE CAT/9708705; Ball JK; Ball JK; Turner BJ
State of Maine comprehensive HIV prevention plan. Rev. Sept. 1996.: Augusta, Maine (11 Parkwood Dr., Augusta 04330) : The Group, 1996 1 v. (various pagings) : ill Unique Identifier : AIDSLINE CAT/9707916; Mercadante DP; Patterson S; Joy JE
The white death.: Sydney, NSW : Angus & Robertson ; New York, NY : HarperCollins, c1996 266 p. : ill., ports Unique Identifier : AIDSLINE CAT/9705272; Cribb J
HIV and community mental healthcare.: Baltimore : Johns Hopkins University Press, c1998 Unique Identifier : AIDSLINE CAT/9709831; Knox MD; Sparks CH
Practicing desire : homosexual sex in the era of AIDS.: Stanford, Calif. : Stanford University Press, 1996 viii, 322 p Unique Identifier : AIDSLINE CAT/9704932; Dowsett GW
The source : news and information from the Texas Department of Health, Bureau of HIV and STD Prevention. -spring 1995.: Austin, TX : The Bureau, v Unique Identifier : AIDSLINE CAT/9700563
AIDS and the law. 3rd ed.: New York : Wiley, 1997 xxxvi, 624 p Unique Identifier : AIDSLINE CAT/9708519; Webber DW
AIDS in Africa and the Caribbean,.: Boulder, Colo. : Westview Press, 1997 xv, 234 p Unique Identifier : AIDSLINE CAT/9708249; Bond GC
HIV kansensho no shinryo : iryo kankeisha no tebiki.: Tokyo : Kokumin Kenko Hoken Chuokai, hatsubai, Shakai Hoken Shuppansha, 1993 159 p. : ill Unique Identifier : AIDSLINE CAT/9512484; Kitamura T
HIV/AIDS and sexually transmitted diseases : WHO policy and strategic orientations.: Geneva : World Health Organization, [1996] 1 v. (various pagings) Unique Identifier : AIDSLINE CAT/9703798
HIV/AIDS fact finder.: Denver : National Conference of State Legislatures, c1993 v, 101 p Unique Identifier : AIDSLINE CAT/9704076
Immunopathogenesis of HIV infection.: Berlin ; New York : Springer, 1997 (Springer seminars in immunopathology ; v. 18, no. 3) Unique Identifier : AIDSLINE CAT/9710141; Fauci AS; Pantaleo G
Mortality due to HIV infection in Hawai'i 1984-1993.: Honolulu, Hawaii : Office of Health Status Monitoring, [1996] 24 p. : ill (R & S report ; issue no. 64) Unique Identifier : AIDSLINE CAT/9707782; Kong VL
On the continuum of HIV/AIDS care : nursing research and practice initiatives.: Geneva : International Council of Nurses, c1995 iv, 142 p Unique Identifier : AIDSLINE CAT/9707958; Schorr TM
Texas HIV/STD update : the quarterly bulletin of the Texas Department of Health, Bureau of HIV & STD Prevention. Vol. 1, no. 1 (summer 1995)-: Austin, Tex. : The Dept., [1995- v Unique Identifier : AIDSLINE CAT/9617138
Management of diarrheal disorders in the HIV+ patient. [videorecording]: Charleston, S.C. : Health Communications Network, Medical University of South Carolina, c1992 1 videocassette (1 hr., 19 min., 57 sec.) : sd., col. ; 1/2 in Unique Identifier : AIDSLINE AV/9616023; Belitsos P
Living sober II. [videorecording]: [Wilmette, Ill.] : G.T. Rogers, c1997 6 videocassettes (125 min., 40 sec.) : sd., col. ; 1/2 in. + 1 manual (i, 44 p.) + 1 workbook (i, 27 p.) Unique Identifier : AIDSLINE AV/9706021; Daley DC; (Producer) Examines the importance of coping successfully with the many problems that confront individuals in early recovery. Stresses the importance of both abstinence from all chemicals and change, both intrapersonal and interpersonal.
[Histopathologic features of cytomegalovirus lymphadenitis in the "immunocompetent" patient. Report of 7 cases]: Ann Pathol. 1996 Sep;16(4):254-60. Unique Identifier : AIDSLINE MED/97182356; Joubert M; Morin C; Moreau A; Heymann MF; Laboisse C; Gaillard F; Laboratoire d'Anatomie Pathologique A, CHRU-Hotel-Dieu, Nantes.; The authors report seven cases of cytomegalovirus lymphadenitis in apparently immunocompetent patients. One patient presented with an infectious mononucleosis-like illness. The main presentation of the others was isolated cervical lymphadenopathies. The lymph node pathology showed
[Role of guided fine needle punction in the diagnosis of deep-seated Aids-related infections. Report of a case of hepato-nodal histoplasmosis]: Ann Pathol. 1996 Sep;16(4):266-70. Unique Identifier : AIDSLINE MED/97182358; Longchampt E; Fabre M; Service d'Anatomie et de Cytologie Pathologiques, Hopital; Bicetre, Le Kremlia Bicetre.; A case of disseminated histoplasmosis diagnosed by fine needle aspiration biopsy is reported. The patient suffering from acquired immune deficiency syndrome (AIDS) had enlarged liver, spleen and mesenteric lymph nodes. Cytological smears prepared from a CT scan guided fine needle aspiration biopsy of one of the lymph
FIV infection of the domestic cat: an animal model for AIDS.: Immunol Today. 1997 Apr;18(4):182-9. Unique Identifier : AIDSLINE MED/97282208; Willett BJ; Flynn JN; Hosie MJ; Dept of Veterinary Pathology, University of Glasgow Veterinary; School, UK. b.willett@vet.gla.ac.uk
Immunopathology of onchocerciasis: a role for eosinophils in onchocercal dermatitis and keratitis.: Chem Immunol. 1997;66:26-40. Unique Identifier : AIDSLINE MED/97256964; Pearlman E; Division of Geographic Medicine, CWRU School of Medicine,; Cleveland, Ohio, USA.; This review has sought to demonstrate that eosinophils have an important role in the immunopathology of onchocercal dermatitis and keratitis. The most compelling evidence is the consistent presence of eosinophils and eosinophil granule proteins at the site of tissue damage, either after parasite death or direct inject
Solution structure of the HIV protease inhibitor acetyl-pepstatin as determined by NMR and molecular modeling.: J Biomol Struct Dyn. 1997 Feb;14(4):421-8. Unique Identifier : AIDSLINE MED/97227320; van Boulanger Y; Senecal L; Sauve G; INRS-Sante, Universite du Quebec, Pointe-Claire, Quebec,; Canada. Yvan_Boulanger@INRS-Sante.UQuebec, CA; The structure of acetyl-pepstatin has been investigated in solution by two-dimensional NMR spectroscopy and molecular modeling. The analysis of DQFCOSY, TOCSY and NOESY spectra lead to a full assignment of the -NMR signals both in DMSO-d6 and in TFE-d3:H2O 1:1. Interproton distances, dihedral angles and exchanger regi
Breast cancer and HIV infection: two case reports [letter]: Eur J Cancer. 1997 Mar;33(3):507-8. Unique Identifier : AIDSLINE MED/97300521; Cuvier C; Espie M; Extra JM; Marty M
Measurement of condom use self-efficacy and outcome expectancies in a geographically diverse group of STD patients.: AIDS Educ Prev. 1997 Feb;9(1):1-13. Unique Identifier : AIDSLINE MED/97237109; DiIorio C; Maibach E; O'Leary A; Sanderson CA; Celentano D; Emory University Rollins School of Public Health, Atlanta, GA; 30322, USA.; The aim of this project was to conduct an initial evaluation among sexually transmitted disease (STD) patients of the psychometric properties of two instruments: the National Institute of Mental Health (NIMH) multisite condom use self-efficacy scale and the NIMH multisite condom use outcome expectancy scale. The condo
Attitudes about AIDS education and condom availability among parents of high school students in New York City: a focus group approach.: AIDS Educ Prev. 1997 Feb;9(1):14-30. Unique Identifier : AIDSLINE MED/97237110; Rafferty Y; Radosh A; Academy for Educational Development, New York, NY 10011, USA.; This paper describes parents views of the New York City Public High School s AIDS Education and Condom Availability Program. It presents findings from 12 focus groups with 81 parents of students at six representative high schools. Focus groups were conducted as part of an independent, comprehensive 3-year evaluation
Understanding the intention of gay and bisexual men to take the HIV antibody test.: AIDS Educ Prev. 1997 Feb;9(1):31-41. Unique Identifier : AIDSLINE MED/97237111; Godin G; Myers T; Lambert J; Calzavara L; Locker D; Ecole des sciences infirmieres, Universite Laval. Quebec,; Canada.; This study offers an explanation for the intention of 1,512 gay and bisexual men to be tested for the HIV antibody. Participants were recruited through 125 gay-identified venues (bars, bathhouses, community dances) across Canada . Self-administered questionnaires assessed respondent
Communication of HIV serostatus between potential sex partners in personal ads.: AIDS Educ Prev. 1997 Feb;9(1):42-8. Unique Identifier : AIDSLINE MED/97237112; Hamers FF; Bueller HA; Peterman TA; Epidemic Intelligence Service, National Center for Prevention; Services, Centers for Disease Control and Prevention, Atlanta, GA; 30333, USA.; We studied reference to HIV in personal ads from 1986 to 1993 to assess knowledge of HIV serostatus as a criterion for selecting sex partners. Personals increased exponentially during 1986 to 1993. Men seeking men (MSM) were more likely (8%) to mention HIV than persons seeking other situations (0% to 1.6%). The propor
Toward reducing the spread of HIV in northeastern Thai villages: evaluation of a village-based intervention.: AIDS Educ Prev. 1997 Feb;9(1):49-69. Unique Identifier : AIDSLINE MED/97237113; Elkins D; Maticka-Tyndale E; Kuyyakanond T; Miller P; Haswell-Elkins M; Queensland Institute of Medical Research, Ontario, Canada.; This paper presents results of the evaluation of an intervention designed for northeastern Thai villages and particularly for village women. The intervention was based on established principles of behavior change, social learning theory, and community health promotion, and it was grounded in elicitation research. A to
An evaluation of teaching methods utilized during an HIV miniresidency course for Thai physicians.: AIDS Educ Prev. 1997 Feb;9(1):70-82. Unique Identifier : AIDSLINE MED/97237114; Zell SC; Department of Internal Medicine, University of Nevada School of; Medicine, USA.; This study examines the efficacy of medical education methods in improving the knowledge base and clinical skills of participants attending a 2-day miniresidency course in HIV infection. Instructional methods included: a didactic lecture format, diagnostic algorithm presentation, color slide photographic demonstration
Migrant laborers and AIDS in the United States: a review of the literature.: AIDS Educ Prev. 1997 Feb;9(1):83-93. Unique Identifier : AIDSLINE MED/97237115; Organista KC; Organista PB; School of Social Welfare, University of California at Berkeley; 94720, USA.; This article reviews the literature on the threat of AIDS to migrant laborers and seasonal farmworkers in the United States . The review includes a sociodemographic profile of migrants in the United States, estimations of HIV prevalence, and a summary of AIDS- and condom-related knowled
A pre-intervention survey to determine understanding of HIV and AIDS in farm worker communities in Zimbabwe.: AIDS Educ Prev. 1997 Feb;9(1):94-110. Unique Identifier : AIDSLINE MED/97237116; Laver SM; van den Borne B; Kok G; Woelk G; Department of Community Medicine, Medical School, University of; Zimbabwe, Harare, Zimbabwe.; A cumulative total of 41,298 AIDS cases have been reported in Zimbabwe as of March 1995. Of concern is the growing evidence of high levels of seroprevalence among rural farm workers. A pre-intervention survey was conducted by interview in one district to examine behavioral factor
Molecular typing of Cryptococcus neoformans: taxonomic and epidemiological aspects.: Int J Syst Bacteriol. 1997 Apr;47(2):432-42. Unique Identifier : AIDSLINE MED/97256929; Boekhout T; van Belkum A; Leenders AC; Verbrugh HA; Mukamurangwa P; Swinne D; Scheffers WA; Yeast Division, Centraalbureau voor Schimmelcultures, Delft, The; Netherlands. T.Boekhout@STM.TuDelft.nl; Pulsed-field gel electrophoresis (PFGE), randomly amplified polymorphic DNA (RAPD) analysis, serotype, and killer toxin sensitivity patterns of a wide range of saprobic, clinical, and veterinary isolates of both varieties of Cryptococcus neoformans were examined. C. neoformans var. neoformans and C. neoformans var. ga
Kikuchi disease (histiocytic necrotizing lymphadenitis) in association with HTLV1.: Br J Dermatol. 1997 Apr;136(4):610-2. Unique Identifier : AIDSLINE MED/97300950; Bataille V; Harland CC; Behrens J; Cook MG; Holden CA; Dermatology Department, St. Helier Hospital, Carshalton, Surrey,; U.K.; We report a 25-year-old male with fever, generalized lymphadenopathy and an erythematosus maculo-papular eruption affecting face and upper body. A diagnosis of Kikuchi disease (necrotizing histiocytic lymphadenitis) was made on lymph node histology. The patient was found to be positive for the human T-cell leukaemia l
Isolated subcutaneous candidal abscess and HIV disease [letter]: Br J Dermatol. 1997 Apr;136(4):647-9. Unique Identifier : AIDSLINE MED/97300970; Manfredi R; Mazzoni A; Nanetti A; Mastroianni A; Coronado OV; Chiodo F
Linoleic and alpha-linolenic acids differently modify the effects of elaidic acid on polyunsaturated fatty acid metabolism and some immune indices in rats.: Br J Nutr. 1997 Apr;77(4):645-56. Unique Identifier : AIDSLINE MED/97300490; Koga T; Nonaka M; Gu JY; Sugano M; Department of Food and Nutrition, Nakamura Gauen College,; Fukuoka, Japan.; To explore whether the metabolic responses to trans, compared with cis, fatty acids depend on the source of dietary polyunsaturated fatty acids (PUFA), male Sprague-Dawley rats, 5 weeks old, were fed on diets containing 30 g oleic (cis) or elaidic (trans) acids/kg in combination with either 70 g perilla oil (alpha-lin
Identification of a loop outside the active site cavity of the human immunodeficiency virus proteases which confers inhibitor specificity.: Biochemistry. 1997 Apr 29;36(17):5128-33. Unique Identifier : AIDSLINE MED/97282564; Towler EM; Thompson SK; Tomaszek T; Debouck C; Department of Molecular Genetics, SmithKline Beecham; Pharmaceuticals, King of Prussia, Pennsylvania 19406, USA.; We have investigated the inhibitor specificity for the proteases of the human immunodeficiency viruses, types 1 and 2. Using a series of related inhibitors, the P1 side chain was confirmed to play a significant role in determining both the absolute and relative affinity for the enzymes. To further define the residues
A leucine zipper-like sequence from the cytoplasmic tail of the HIV-1 envelope glycoprotein binds and perturbs lipid bilayers.: Biochemistry. 1997 Apr 29;36(17):5157-69. Unique Identifier : AIDSLINE MED/97282568; Kliger Y; Shai Y; Department of Membrane Research and Biophysics, Weizmann; Institute of Science, Rehovot, Israel.; HIV-1 transmembrane envelope glycoprotein (gp41) has an unusually long cytoplasmic domain that has secondary associations with the inner leaflet of the membrane. Two highly amphiphatic alpha-helices in the cytoplasmic domain of gp41 have previously been shown to interact with lipid bilayers. We have detected a highly
Cytotoxicity of graft-derived lymphocytes: specific for donor heart endothelial cells?: J Heart Lung Transplant. 1997 Feb;16(2):209-15. Unique Identifier : AIDSLINE MED/97213167; Jutte NH; Knoop CJ; Heijse P; Balk AH; Mochtar B; Claas FH; Weimar W; Department of Internal Medicine I, University Hospital; Rotterdam/Dijkzigt, Erasmus University Rotterdam, The; Netherlands.; BACKGROUND: Previously, we showed that lymphocytes cultured from cardiac allografts can lyse lymphoid cell lines from donor origin. Because endothelial cell form the first allogeneic barrier to be encountered in vivo, the reactivity of graft-infiltrating cells against donor heart-derived endothelial cells (DoHEC) may
Cytokine messenger RNA expression by donor-specific cytotoxic T-cell clones after allogeneic heart transplantation.: J Heart Lung Transplant. 1997 Feb;16(2):216-21. Unique Identifier : AIDSLINE MED/97213168; Van Hoffen E; Gmelig-Meyling FH; Bosboom-Kalsbeek KC; Hu H; De Jonge N; Tilanus MG; Lahpor JR; De Weger RA; Department of Pathology, University Hospital, Utrecht, The; Netherlands.; BACKGROUND: After heart transplantation, expression of various cytokines can be detected in endomyocardial biopsy specimens both in the presence and in the absence of rejection. In this study we have analyzed the contribution of donor-specific CD8+ cytotoxic T cells to intragraft cytokine expression. METHODS: T cells
[AIDS-associated illnesses in radiologic diagnosis: overview and differential diagnosis]: Aktuelle Radiol. 1997 Mar;7(2):69-73. Unique Identifier : AIDSLINE MED/97261417; Rademaker J; Frahm C; Department of Medicine, Beth Israel Medical Center, New York,; USA.
Living with HIV and AIDS. Vancouver Conference Review.: AIDS Care. 1997 Feb;9(1):103-6. Unique Identifier : AIDSLINE MED/97300907; du Plessis P; York Clinic, Lewisham and Guy's Mental Health NHS Trust, Guys; Hospital, London, UK.
Suicidal behaviours and euthanasia. Vancouver Conference Review.: AIDS Care. 1997 Feb;9(1):106-8. Unique Identifier : AIDSLINE MED/97300908; Starace F; Ogden RD; Department of Primary Care and Population Sciences, Royal Free; Hospital School of Medicine, London, UK.
HIV testing. Vancouver Conference Review.: AIDS Care. 1997 Feb;9(1):108-15. Unique Identifier : AIDSLINE MED/97300909; Miller R; Royal Free Hospital and School of Medicine, London, UK.
Migration and ethnicity issues. Vancouver Conference Review.: AIDS Care. 1997 Feb;9(1):115-9. Unique Identifier : AIDSLINE MED/97300910; Haour-Knipe M; University Institute of Social and Preventive Medicine, Lausanne,; Switzerland.
Social-cultural aspects. Vancouver Conference Review.: AIDS Care. 1997 Feb;9(1):119-23. Unique Identifier : AIDSLINE MED/97300911; Kippax S; National Centre in HIV Social Research Macquarie University, NSW,; Australia.
A dialogue between the sexes. Vancouver Conference Review.: AIDS Care. 1997 Feb;9(1):123-5. Unique Identifier : AIDSLINE MED/97300912; Ankrah EM; Family Health International/AIDSCAP, Arlington, VA 22201, USA.
Participatory evaluation of counselling, medical and social services of The AIDS Support Organization (TASO) in Uganda.: AIDS Care. 1997 Feb;9(1):13-26. Unique Identifier : AIDSLINE MED/97300890; Kaleeba N; Kalibala S; Kaseje M; Ssebbanja P; Anderson S; van Praag E; Tembo G; Katabira E; Joint United Nations Programme on HIV/AIDS, Geneva, Switzerland.; The AIDS Support Organization (TASO) is an indigenous non-governmental organization (NGO) of HIV-infected and affected people in Uganda . TASO provides counselling, social support, medical and nursing care for opportunistic infections at 7 centres affiliated to district hospitals in
Heterogeneity of home care assistance needs of people with AIDS.: AIDS Care. 1997 Feb;9(1):27-33. Unique Identifier : AIDSLINE MED/97300891; Milanese G; Abeni D; Cancelli A; Brancato G; Fabrizi E; Borgia P; Perucci CA; Rocchi G; Division of Infectious Diseases, School of Medicine, Tor Vergata; University, Rome, Italy.; A multidisciplinary home care service for people with AIDS (PWAs) was started in Rome in September 1990. This paper describes the features of the home care service offered by the Associated Health Care Workers Co-operative (OSA), an example of the integration of private and state systems. We detail the types and numb
Health education. Vancouver Conference Review.: AIDS Care. 1997 Feb;9(1):35-9. Unique Identifier : AIDSLINE MED/97300892; Aggleton P; Thomas Coram Research Unit, University of London, UK.
Grief. Vancouver Conference Review.: AIDS Care. 1997 Feb;9(1):39-43. Unique Identifier : AIDSLINE MED/97300893; Folkman S; Chesney M; Center for AIDS Prevention Studies, University of California at; San Francisco 94105, USA.
Asia. Vancouver Conference Review.: AIDS Care. 1997 Feb;9(1):43-9. Unique Identifier : AIDSLINE MED/97300894; Brown T; Program on Population, East-West Center, Honolulu, HI 96848-1601,; USA.
Disclosure. Vancouver Conference Review.: AIDS Care. 1997 Feb;9(1):49-53. Unique Identifier : AIDSLINE MED/97300895; Bor R; Department of Psychology, City University School of Social; Sciences, London, UK.
An epidemic of apprehension: questions about HIV/AIDS to an east African newspaper health advice column.: AIDS Care. 1997 Feb;9(1):5-12. Unique Identifier : AIDSLINE MED/97300889; Asera R; Bagarukayo H; Shuey D; Barton T; Charles A. Dana Center, University of Texas at Austin 78751, USA.; asera@mail.utexas.edu; While AIDS awareness is almost universal in Uganda , cultural values discourage open discussion of sexual behaviour. Thus many questions remain unasked, especially in public. This study managed to analyse some of these queries by examining 1252 letters written spontaneously to a new
Drug use. Vancouver Conference Review.: AIDS Care. 1997 Feb;9(1):53-7. Unique Identifier : AIDSLINE MED/97300896; Des Jarlais DC; Friedman SR; Hagan H; Paone D; Vlahov D; Beth Israel Medical Center, New York, NY 10003, USA.
Interventions--gay men. Vancouver Conference Review.: AIDS Care. 1997 Feb;9(1):57-62. Unique Identifier : AIDSLINE MED/97300897; Flowers P; MRC Medical Sociology Unit, Glasgow, UK.
Adolescence. Vancouver Conference Review.: AIDS Care. 1997 Feb;9(1):62-6. Unique Identifier : AIDSLINE MED/97300898; Elford J; Department of Primary Care and Population Sciences, Royal Free; Hospital School of Medicine, London, UK.
School-based sex education. Vancouver Conference Review.: AIDS Care. 1997 Feb;9(1):66-9. Unique Identifier : AIDSLINE MED/97300899; Wight D; MRC Medical Sociology Unit, Glasgow, UK.
Pregnancy and childbirth. Vancouver Conference Review.: AIDS Care. 1997 Feb;9(1):69-77. Unique Identifier : AIDSLINE MED/97300900; Sherr L; Department of Primary Care and Population Sciences, Royal Free; Hospital School of Medicine, London, UK.
Women's news. Vancouver Conference Review.: AIDS Care. 1997 Feb;9(1):77-82. Unique Identifier : AIDSLINE MED/97300901; Gorna R; Terrence Higgins Trust, London, UK.
Orphans. Vancouver Conference Review.: AIDS Care. 1997 Feb;9(1):82-7. Unique Identifier : AIDSLINE MED/97300902; Foster G; Department of Paediatrics, Mutare Provincial Hospital, Zimbabwe.
Children. Vancouver Conference Review.: AIDS Care. 1997 Feb;9(1):87-91. Unique Identifier : AIDSLINE MED/97300903; Thorne C; Department of Paediatric Epidemiology, Institute of Child Health,; London, UK.
Prisons. Vancouver Conference Review.: AIDS Care. 1997 Feb;9(1):92-5. Unique Identifier : AIDSLINE MED/97300904; Turnbull P; Centre for Research on Drugs and Health Behaviour, University of; London, UK.; Interesting and innovative programmes to tackle the problems associated with HIV/AIDS in prison have been and are being tried throughout the world. However, a number of political, legal and cultural barriers exist hindering the development of effective prevention and care and treatment approaches.
Volunteers. Vancouver Conference Review.: AIDS Care. 1997 Feb;9(1):95-8. Unique Identifier : AIDSLINE MED/97300905; Ross MW; Center for Health Promotion Research and Development, School of; Public Health, University of Texas, Houston 77225, USA.
Natural history. Vancouver Conference Review.: AIDS Care. 1997 Feb;9(1):98-103. Unique Identifier : AIDSLINE MED/97300906; Sabin C; Department of Primary Care and Population Sciences, Royal Free; Hospital School of Medicine, London, UK.
[The AIDS patient in anesthesia]: Anasthesiol Intensivmed Notfallmed Schmerzther. 1997 Feb;32(2):87-97. Unique Identifier : AIDSLINE MED/97245768; Jalowy A; Flesche CW; Lorenz C; Zentrum fur Anasthesiologie, Heinrich-Heine-Universitat,; Dusseldorf.; Treatment of a patient with Acquired Immune Deficiency Syndrome (AIDS) is very challenging, and makes great demands on the anaesthesiologist. Any of an AIDS patient s vital organ systems may be compromised, either by the human immunodeficiency virus (HIV) itself, opportunistic infections, by tumours, or as a result of
Immunity aging. I. The chronic perduration of the thymus acute involution at puberty? Or the participation of the lymphoid organs and cells in fatal physiologic decline? [editorial]: Biomed Pharmacother. 1997;51(2):49-57. Unique Identifier : AIDSLINE MED/97305201; Mathe G; Institut de Cancerologie et d'Immunologie & Hopital Suisse de; Paris, France.; The author has focused the subject on the perduration of puberty thymus involution as a cause of immunity aging, a term in which he does not include senescence. The decrease between immune reactions against HIV1 at 25 years of age and those at 35 is considerable; the decrease is also indirectly revealed by spontaneous
Complementary and alternative medicine and HIV/AIDS. Part I: Issues and context.: J Assoc Nurses AIDS Care. 1997 Jan-Feb;8(1):23-31. Unique Identifier : AIDSLINE MED/97239585; MacIntyre RC; Holzemer WL; Philippek M; Samuel Merritt College, Oakland, CA, USA.; This paper reviews the definitions of complementary and alternative medicine (CAM) and adopts the definition, Complementary and alternative medicine is defined through a social process as those practices that do not form part of the dominant system for managing health and disease (Jonas, 1996, p.1). The authors revi
Coordinating a large multicentered HIV research project.: J Assoc Nurses AIDS Care. 1997 Jan-Feb;8(1):41-50. Unique Identifier : AIDSLINE MED/97239586; Cohen HL; Davis L; Hunter J; Carp D; Geromanos K; Sunkle S; University of California, Los Angeles, USA.; Coordinating a large multicentered pediatric HIV clinical research study is particularly challenging for nurses. The cohort of patients and their families face multiple stressors, which make recruitment and compliance difficult. Additionally, when many departments within the institution are involved, coordination is o
Managing depression among people with HIV disease.: J Assoc Nurses AIDS Care. 1997 Jan-Feb;8(1):51-67. Unique Identifier : AIDSLINE MED/97239587; Valente SM; Saunders JM; University of Southern California, Los Angeles, USA.; Many people with HIV suffer from depression, which responds to antidepressants, counseling, education, and cognitive strategies. Untreated depression hinders treatment compliance and increases risk of suicide. Management and complications of major depression are described. The evaluation of rational suicide is examine
Postexposure prophylaxis after an occupational exposure to HIV.: J Assoc Nurses AIDS Care. 1997 Jan-Feb;8(1):83-7. Unique Identifier : AIDSLINE MED/97239588; Porche DJ
Social support for HIV-infected mothers: relation to HIV care seeking.: J Assoc Nurses AIDS Care. 1997 Jan-Feb;8(1):91-8. Unique Identifier : AIDSLINE MED/97239589; Williams AB; Shahryarinejad A; Andrews S; Alcabes P; Yale School of Nursing, New Haven, CT, USA.; A cross-sectional survey was conducted to identify sources of social support for 92 HIV-seropositive mothers and to examine the relationship between social support and initiation of health care after a positive test for HIV antibody. Main outcome measures were self-reported source and amount of social support and leng
Thymocyte Fas expression is dysregulated in myasthenia gravis patients with anti-acetylcholine receptor antibody.: Blood. 1997 May 1;89(9):3287-95. Unique Identifier : AIDSLINE MED/97275140; Moulian N; Bidault J; Truffault F; Yamamoto AM; Levasseur P; Berrih-Aknin S; CNRS URA 1159 and the Departement de Chirurgie Thoracique,; Hopital Marie-Lannelongue, Le Plessis Robinson, France.; Myasthenia gravis (MG) is a human autoimmune disease mediated by anti-acetylcholine receptor (AChR) antibodies. The thymus is probably the site where the autoimmune response is triggered and maintained. Recent reports have linked various autoimmune disease with defective Fas expression. We thus analyzed Fas expression
Variable immortalizing potential and frequent virus latency in blood-derived T-cell clones infected with human T-cell leukemia virus type I.: Blood. 1997 May 1;89(9):3303-14. Unique Identifier : AIDSLINE MED/97275142; Richardson JH; Hollsberg P; Windhagen A; Child LA; Hafler DA; Lever AM; Department of Medicine, University of Cambridge, United Kingdom.; Human T-cell leukemia virus type I (HTLV-I)-infected T cells expanded in vitro by single-cell cloning provide a unique system for investigating virus-cell interactions in nonimmortalized T cells. By analysis of clones generated randomly from the blood of virus carriers, we confirm that CD4 T cells are the major reserv
Cloning and characterization of exodus, a novel beta-chemokine.: Blood. 1997 May 1;89(9):3315-22. Unique Identifier : AIDSLINE GENBANK/U64197; Hromas R; Gray PW; Chantry D; Godiska R; Krathwohl M; Fife K; Bell GI; Takeda J; Aronica S; Gordon M; Cooper S; Broxmeyer HE; Klemsz MJ; Department of Hematology/Oncology and the Walther Oncology; Center, Indiana University Medical Center, Indianapolis 46202,; USA.; Chemokines are a family of related proteins that regulate leukocyte infiltration into inflamed tissue. Some chemokines such as MIP-1 alpha also inhibit hematopoietic progenitor cell proliferation. Recently, three chemokines, MIP-1 alpha, MIP-1 beta, and RANTES, have been found to significantly decrease human immunodef
Activation of the NF-kappaB pathway by inflammatory stimuli in human neutrophils.: Blood. 1997 May 1;89(9):3421-33. Unique Identifier : AIDSLINE MED/97275156; McDonald PP; Bald A; Cassatella MA; Department of General Pathology, University of Verona, Italy.; Activated neutrophils have the ability to upregulate the expression of many genes, in particular those encoding cytokines and chemokines, and to subsequently release the corresponding proteins. Although little is known to date concerning the regulation of gene transcription in neutrophils, it is noteworthy that many o
Differential effects of interleukin-13 on cytomegalovirus and human immunodeficiency virus infection in human alveolar macrophages.: Blood. 1997 May 1;89(9):3443-50. Unique Identifier : AIDSLINE MED/97275158; Hatch WC; Freedman AR; Boldt-Houle DM; Groopman JE; Terwilliger EF; Division of Experimental Medicine, Beth Israel Deaconess Medical; Center, Harvard Medical School, Boston, MA 02215, USA.; Alveolar macrophages, which form a principal line of defense against a variety of pulmonary pathogens, may themselves be infected by viruses like human immunodeficiency virus-1 (HIV-1), which impair their defensive functions. Interleukin-13 (IL-13), a multifunctional cytokine, has been considered for therapeutic use b
The role of B7 costimulation by murine acute myeloid leukemia in the generation and function of a CD8+ T-cell line with potent in vivo graft-versus-leukemia properties.: Blood. 1997 May 1;89(9):3477-85. Unique Identifier : AIDSLINE MED/97275162; Boyer MW; Vallera DA; Taylor PA; Gray GS; Katsanis E; Gorden K; Orchard PJ; Blazar BR; Department of Pediatrics, University of Minnesota Hospital and; Clinic, Minneapolis, USA.; Relapse is more frequent after autologous than allogeneic bone marrow transplantation (BMT), due in part to lack of T-lymphocyte mediated allogeneic graft-versus-leukemia (GVL) effects. Infusions of leukemia-reactive T cells to patients after autologous BMT may be a means for providing a GVL effect. Costimulation of T
[Prevalence of hepatitis C virus and human immunodeficiency virus infection among female prison inmates in Japan]: Nippon Koshu Eisei Zasshi. 1997 Jan;44(1):55-60. Unique Identifier : AIDSLINE MED/97248940; Nara K; Kawano M; Igarashi M; Department of Emergency and Critical Care Medicine, Jichi Medical; School, Tochigi, Japan.; To investigate the prevalence of hepatitis C virus and human immunodeficiency virus infection in female inmates, 504 out of 513 female inmates in a certain female prison in Japan were tested for anti-hepatitis C virus, anti-hepatitis B virus, anti-hepatitis A virus and anti-human im
Cost of medication therapy in ambulatory HIV-infected patients.: Ann Pharmacother. 1997 Mar;31(3):303-7. Unique Identifier : AIDSLINE MED/97219645; Nykamp D; Barnett CW; Lago M; Parham DL; Fernandez ES; Mercer University School of Pharmacy, Atlanta, GA 30341, USA.; OBJECTIVE: To examine the use and cost associated with prescribed medications as well as the use of over-the-counter medications and nontraditional therapies among ambulatory HIV-infected patients at Ryan White Title IIIb grantee centers. METHODS: Study participants (n = 223) were enrolled from eight centers across th
Prophylaxis of anaphylactoid reaction to antituberculous drugs [letter]: Ann Pharmacother. 1997 Mar;31(3):373-4. Unique Identifier : AIDSLINE MED/97219662; Kevorkian JP; Seroux C; Deharbe S; Salord JM; Bergmann JF
Pharmacotherapy of HIV dementia.: Ann Pharmacother. 1997 Apr;31(4):457-73. Unique Identifier : AIDSLINE MED/97255662; Melton ST; Kirkwood CK; Ghaemi SN; Department of Pharmacy and Pharmaceutics, School of Pharmacy,; Virginia Commonwealth University, Richmond 23298, USA.; OBJECTIVE: To review the clinical presentation and management of cognitive impairment associated with central nervous system HIV type 1 (HIV-1) infection. DATA SOURCES: A MEDLINE search pertaining to HIV-related dementia (HIV-D) and pharmacologic management was performed. Additiona
T cell subsets in immunologically-mediated glomerulonephritis.: Histol Histopathol. 1997 Jan;12(1):241-50. Unique Identifier : AIDSLINE MED/97197763; van Alderwegen IE; Bruijn JA; de Heer E; Leiden University, Department of Pathology, The Netherlands.; Until recently, research on the pathogenesis of glomerulonephritis has been mainly focused on the characterization of humoral immune responses in the initiation of glomerular injury. However, there is a growing recognition that both cellular and humoral immune responses, in varying proportions, are involved in the pat
Single-step purification of recombinant wild-type and mutant HIV-1 reverse transcriptase.: Protein Expr Purif. 1996 Feb;7(1):27-32. Unique Identifier : AIDSLINE MED/96209928; Fletcher RS; Holleschak G; Nagy E; Arion D; Borkow G; Gu Z; Wainberg MA; Parniak MA; Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-; Jewish General Hospital, Montreal, Canada.; We have devised a single-step method that enables purification of HIV-1 recombinant reverse transcriptase directly from bacterial lysates in less than 2 h. Clarified lysates are applied to commercial Q- and S-matrix cartridge columns connected in series. The columns are washed with low-salt buffer to remove unbound pr
Features of the cytokines secreted by adult T cell leukemia (ATL) cells.: Leuk Lymphoma. 1996 May;21(5-6):443-7. Unique Identifier : AIDSLINE MED/97013287; Yamada Y; Ohmoto Y; Hata T; Yamamura M; Murata K; Tsukasaki K; Kohno T; Chen Y; Kamihira S; Tomonaga M; Department of Hematology, Atomic Disease Institute, Nagasaki; University School of Medicine, Japan.; Adult T cell leukemia (ATL) cells show a mature helper-inducer T cell phenotype and are thought to secrete many kinds of cytokines in vivo, complicating the clinical features in these patients. In an attempt to specify the cytokines produced by ATL cells, we measured the cytokine concentration in the culture supernata
The impact of red cell substitutes on the blood service in Japan.: Artif Cells Blood Substit Immobil Biotechnol. 1997 Jan-Mar;25(1-2):53-60. Unique Identifier : AIDSLINE MED/97237148; Sekiguchi S; Hokkaido Red Cross Blood Center, Sapporo, Japan.; The total number of blood donors in 1994 was 6.6 millions, and 200 ml whole blood donation occupied 41.8% of all donations, whereas 400 ml and apheresis donations occupied 35.6%, 22.5% of all donations respectively. From the donated blood, about 8.35 million bags of blood components were prepared and were used for blo
[Surface-active substances in the arsenal of agents against AIDS]: Mikrobiol Z. 1997 Jan-Feb;59(1):87-97. Unique Identifier : AIDSLINE MED/97252110; Krivoshein IuS; Krivorutchenko IuL; Only nucleoside analogues such as zidovudine have been widely used to improve the clinical state of patients with AIDS till now. Their use has a number of eliminations. Nevertheless, the anti-HIV properties of many different substances have been shown. Some of them contain hydrophobic and polar parts of molecules and
HIV infection: the spectrum of symptoms and disease in male and female patients attending a London hospice.: Palliat Med. 1997 Mar;11(2):152-8. Unique Identifier : AIDSLINE MED/97301092; Kelleher P; Cox S; McKeogh M; Antigen Presentation Research Group, Imperial College School of; Medicine at Northwick Park, Harrow, UK.; To delineate the demographic features and clinical profile of male and female individuals utilizing a respite, rehabilitation and hospice centre in London, a retrospective study of patient notes was undertaken. The subjects were 59 male and 59 female HIV patients at first admission to the hospice. The study revealed c
Validity of a decision tree for predicting active pulmonary tuberculosis.: Am J Respir Crit Care Med. 1997 May;155(5):1711-6. Unique Identifier : AIDSLINE MED/97299732; El-Solh A; Mylotte J; Sherif S; Serghani J; Grant BJ; Department of Medicine, State University of New York at Buffalo,; 14215, USA.; The recent outbreaks of multidrug-resistant strains of M. tuberculosis in health care facilities has increased concern over its transmission in health care facilities. Isolation has been recommended for all patients suspected to have tuberculosis even though the feasibility and the cost of this recommendation can be s
Lack of clinical utility of bronchoalveolar lavage cultures for cytomegalovirus in HIV infection.: Am J Respir Crit Care Med. 1997 May;155(5):1723-8. Unique Identifier : AIDSLINE MED/97299734; Mann M; Shelhamer JH; Masur H; Gill VJ; Travis W; Solomon D; Manischewitz J; Stock F; Lane HC; Ognibene FP; Critical Care Medicine Department, Warren G. Magnuson Clinical; Center, National Cancer Institute, National Institutes of Health,; Bethesda, Maryland 20892-1662, USA.; This study assessed the presence of cytomegalovirus ( CMV ) in bronchoalveolar lavage (BAL) in three subpopulations of HIV-infected patients and correlated its presence with clinical status during 3 mo of follow-up. Nineteen as
Effects of neurokinin depletion on airway inflammation induced by chronic antigen exposure.: Am J Respir Crit Care Med. 1997 May;155(5):1739-47. Unique Identifier : AIDSLINE MED/97299737; Tiberio IF; Turco GM; Leick-Maldonado EA; Sakae RS; Paiva SO; do Patrocinio M; Warth TN; Lapa e Silva JR; Saldiva PH; Martins MA; Department of Medicine, Faculty of Medicine, University of Sao; Paulo, Brazil.; We assessed the effects of neurokinin (tachykinin) depletion by capsaicin (CAP) treatment on airway inflammation induced by repeated ovalbumin (OA) aerosol exposures (twice a week for 4 wk) in guinea pigs. The animals were then anesthetized, tracheostomized, mechanically ventilated and challenged with ovalbumin aeroso
Lack of association of induration size with HIV infection among drug users reacting to tuberculin [letter]: Am J Respir Crit Care Med. 1997 May;155(5):1816-7. Unique Identifier : AIDSLINE MED/97299749; Daniel TM
[Ultrasonography of changes in the retroperitoneal vessels and perivascular spaces during retroviral infection: preliminary results]: Sante. 1997 Jan-Feb;7(1):25-31. Unique Identifier : AIDSLINE MED/97241165; N'gbesso RD; N'goan AM; Tahirou K; Diabate K; Keita AK; Service de radiologie, CHU de Yopougon, Cote d'lvoire.; The abdomen in patients with acquired immunodeficiency syndrome (AIDS) is subject to various damage. In AIDS patients, manifestations in the retroperitoneal region, including apparent changes in the pancreas, kidney and lymph nodes, have been well described in the radiological literature. However, abnormalities of the
[Attendance at a health center by clandestine prostitutes in Djibouti]: Sante. 1997 Jan-Feb;7(1):5-10. Unique Identifier : AIDSLINE MED/97241162; Philippon M; Saada M; Kamil MA; Houmed HM; Centre de prophylaxie, Djibouti.; The extent of clandestine prostitution in Djibouti is difficult to evaluate. Due to the secrecy of the prostitutes and often their low level of education, the follow-up of these patients is also difficult. A sexually transmitted disease clinic specialized in the treatment of pros
Gastrointestinal manifestations in pediatric AIDS.: Pediatr Pathol Lab Med. 1997 Mar-Apr;17(2):171-208. Unique Identifier : AIDSLINE MED/97241147; Kahn E; Department of Pathology, North Shore University Hospital,; Manhasset, New York 11030, USA.; The pathologic changes in the gastrointestinal tract of children with AIDS are variable, clinically significant, and reflect multisystemic disease processes. Inflammation, changes in the lymphoid tissue, miscellaneous lesions, and tumors are documented in 58 patients in addition to cases reported in the literature. Cy
Not just another Fab: the crystal structure of a TcR-MHC-peptide complex.: Structure. 1997 Feb 15;5(2):159-63. Unique Identifier : AIDSLINE MED/97184682; Jardetzky T; Department of Biochemistry, Molecular Biology and Cell Biology,; Northwestern University, Evanston, IL 60208, USA.; jardetz@tochtli. biochem.nwu.edu; The structure of a ternary complex formed between a T-cell receptor, a major histocompatibility complex (MHC) protein and a viral peptide provides new insights into the cellular immune response. The results provide a molecular basis for understanding the development of T cells and the reactions leading to transplant r
State hospitals' responses to the sexual behavior of psychiatric inpatients.: Psychiatr Serv. 1997 Mar;48(3):398-9. Unique Identifier : AIDSLINE MED/97210072; Buckley PF; Hyde JL; Northcoast Behavioral Healthcare System, Northfield, OH 44067,; USA.; To determine state psychiatric hospitals responses to sexual behavior among inpatients, the authors sent a questionnaire to the directors of 86 state facilities. Eighty-eight percent of the 57 respondents considered sexual behavior to be a clinical problem. Most had a policy addressing sexual activities among patientb
Bilateral parotid sialolithiasis in a patient with acquired immunodeficiency syndrome and immunoglobulin G multiple myeloma.: Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1997 May;83(5):552-4. Unique Identifier : AIDSLINE MED/97303490; Ottaviani F; Galli A; Lucia MB; Ventura G; Institute of Otolaryngology, Catholic University, Rome, Italy.; Bilateral multiple parotid calculi, which are uncommonly diagnosed in the normal population, have never been reported in patients infected with human immunodeficiency virus. Herein we report a case of bilateral parotid sialolithiasis in a patient who had acquired immunodeficiency syndrome and was affected by multiple b
Immunoregulatory effects of morphine on human lymphocytes.: Clin Diagn Lab Immunol. 1997 Mar;4(2):127-32. Unique Identifier : AIDSLINE MED/97220482; Nair MP; Schwartz SA; Polasani R; Hou J; Sweet A; Chadha KC; Department of Medicine, Buffalo General Hospital, State; University of New York at Buffalo 14203, USA.; It is now well established that parenteral drug abuse is a significant risk factor for contracting human immunodeficiency virus type 1 (HIV-1) infection and subsequently developing AIDS. Earlier studies have shown that morphine can modulate various immune responses and therefore support the premise that morphine is a b
Inter- and intrainstitutional evaluation of automated volumetric capillary cytometry for the quantitation of CD4- and CD8-positive T lymphocytes in the peripheral blood of persons infected with human immunodeficiency virus. Site Investigators and the NIAID New CD4 Technologies Focus Group.: Clin Diagn Lab Immunol. 1997 Mar;4(2):173-9. Unique Identifier : AIDSLINE MED/97220489; O'Gorman MR; Gelman R; Children's Memorial Hospital, Northwestern University Medical; School, Chicago, Illinois 60614, USA.; Volumetric capillary cytometry (VCC) is a new technology that involves the detection and enumeration of dually fluorochrome-labeled cells in a precise volume. We compared the accuracy and precision of VCC with the accuracy and precision of flow cytometry and hematology (F&H) for the measurement of the absolute numb
Lack of association of Borna disease virus and human T-cell leukemia virus type 1 infections with psychiatric disorders among Japanese patients.: Clin Diagn Lab Immunol. 1997 Mar;4(2):189-94. Unique Identifier : AIDSLINE GENBANK/D85768; Kubo K; Fujiyoshi T; Yokoyama MM; Kamei K; Richt JA; Kitze B; Herzog S; Takigawa M; Sonoda S; Department of Neuropsychiatry, Faculty of Medicine, Kagoshima; University, Japan.; Borna disease virus (BDV) infection has been suspected to be a possible etiological factor in human psychiatric disorders and recently in chronic fatigue syndrome. Evidence of the correlation of BDV infection with these disorders remained unclear. Kagoshima is known to be one of the major areas in which human T-cell l
CD69 expression reliably predicts the anti-CD3-induced proliferative response of lymphocytes from human immunodeficiency virus type 1-infected patients.: Clin Diagn Lab Immunol. 1997 Mar;4(2):217-22. Unique Identifier : AIDSLINE MED/97220497; Prince HE; Lape-Nixon M; MRL Reference Laboratory, Cypress, California 90630, USA.; Published studies suggest that mitogenic responses of lymphocytes can be reliably assessed by monitoring the expression of lymphocyte surface CD69 after 24 h of culture with the stimulant. We tested this hypothesis by determining the ability of lymphocyte CD69 expression to predict the outcome (normal or abnormal) of
Immune suppression in calves with bovine immunodeficiency virus.: Clin Diagn Lab Immunol. 1997 Mar;4(2):232-5. Unique Identifier : AIDSLINE MED/97220501; Zhang S; Wood C; Xue W; Krukenberg SM; Chen Q; Minocha HC; Department of Diagnostic Medicine/Pathobiology, College of; Veteri