Treatment of Burkitt's lymphoma in HIV-positive patients. NLM AIDSLINE Important note: Information in this article was accurate in 1997. The state of the art may have changed since the publication date.

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Treatment of Burkitt's lymphoma in HIV-positive patients.

Biomed Pharmacother. 1996;50(9):447-50. Unique Identifier : AIDSLINE MED/97145474
Straus DJ; Department of Medicine, Memorial Sloan-Kettering Cancer Center, New; York, NY 10021, USA.

Abstract: Many Burkitt's-type non-Hodgkin lymphomas (NHL) in patients without HIV infection are curable with current brief high-dose combination chemotherapy regimens. Burkitt's-type lymphomas (BL) comprise 30-40% of HIV-associated NHL. Their morphologic, clinical, cytogenetic and molecular genetic characteristics are similar to those of sporadic BL unassociated with HIV infection. They often occur in less immunosuppressed HIV-infected individuals than the other types of NHL. Most patients with HIV-associated NHL benefit as much from low-dose as from standard or high-dose chemotherapy with less toxicity. However, there may be a subpopulation of HIV-infected patients with Burkitt's-type NHL and well preserved immune status who may benefit from high-dose chemotherapy programs that are effective for BL patients without HIV infection.
Keywords: *Burkitt's Lymphoma/COMPLICATIONS *Burkitt's Lymphoma/DRUG THERAPY *HIV Infections/COMPLICATIONS *HIV Seropositivity/COMPLICATIONS *Lymphoma, AIDS-Related/DRUG THERAPYKWDburkitt'slymphoma/complicationsKWDburkitt'slymphoma/drugtherapyKWDhivinfections/complicationsKWDhivseropositivity/complicationsKWDlymphoma,aids-related/drugtherapy
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Copyright © 1997 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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