Reference intervals of CD3, CD4, CD8, CD4/CD8, and absolute CD4 values in Asian and Non-Asian populations. NLM AIDSLINE Important note: Information in this article was accurate in 1997. The state of the art may have changed since the publication date.

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Reference intervals of CD3, CD4, CD8, CD4/CD8, and absolute CD4 values in Asian and Non-Asian populations.

Cytometry. 1996 Sep 15;26(3):231-2. Unique Identifier : AIDSLINE MED/97044326
Howard RR; Fasano CS; Frey L; Miller CH; Department of Pathology, University of California Medical Center,; Davis at Sacramento, USA.

Abstract: A study to determine reference intervals in normal Asian and non-Asian populations for CD3 (T cells), CD4 (T helper/inducer cells), CD8 (T suppressor/cytotoxic cells), and for the CD4/CD8 ratio and absolute CD4 lymphocyte count was performed. Coulter Clone/Cytostat reagents were used. The samples were lysed using the Coulter Q-Prep and analyzed on the Coulter Profile II flow cytometer. The Asian population appeared to have a lower mean percentage of CD3 and CD4 cells, a lower CD4/CD8 ratio, and lower absolute CD4 lymphocytes. These findings indicate that race should be a consideration in determining reference intervals for immunophenotyping for CD3, CD4, and CD8.
Keywords: *Antigens, CD/ANALYSIS *Flow Cytometry/STANDARDS *Immunophenotyping/STANDARDSKWDantigens,cd/analysisKWDflowcytometry/standardsKWDimmunophenotyping/standards
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M9741543

Copyright © 1997 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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