A case of hepatocellular carcinoma in HIV-infected patient. NLM AIDSLINE Important note: Information in this article was accurate in 1997. The state of the art may have changed since the publication date.

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A case of hepatocellular carcinoma in HIV-infected patient.

Hepatogastroenterology. 1996 Jul-Aug;43(10):1067-72. Unique Identifier : AIDSLINE MED/97038760
Tanaka T; Imamura A; Masuda G; Ajisawa A; Negishi M; Tanaka S; Koike M; Hattori N; Liver Unit, Tokyo Metropolitan Komagome Hospital, Japan.

Abstract: Persistent human immunodeficiency virus (HIV) infection induces an immuno-suppressive state and therefore malignant tumors are a very common complication. Hepatocellular carcinoma is very rare, however, because it is associated with chronic liver disease by the persistent infection of hepatitis B or C virus (HBV or HCV). We reported a case of HCC with HIV infection who had no evidence of HBV or HCV infection, and that had a rapid growth and active pulmonary metastases. Pathological findings of the resected liver showed moderately differentiated HCC and no chronic liver disease. Despite efforts to find potential HBV integration in tumor and non-tumor tissue, none was observed. To our knowledge, this is the first report of HCC in HIV-infected patient with no evidence of hepatitis virus infection.
Keywords: *Carcinoma, Hepatocellular/COMPLICATIONS *HIV Infections/COMPLICATIONS *Liver Neoplasms/COMPLICATIONSKWDcarcinoma,hepatocellular/complicationsKWDhivinfections/complicationsKWDliverneoplasms/complications
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