[Movement disorders and AIDS] NLM AIDSLINE Important note: Information in this article was accurate in 1996. The state of the art may have changed since the publication date.

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[Movement disorders and AIDS]

Neurologia. 1996 Feb;11(2):70-5. Unique Identifier : AIDSLINE MED/96221732
Iranzo A; Kulisevsky J; Cadafalch J; Serrano C; Grau JM; Servicio de Neurologia, Hospital de la Santa Creu i Sant Pau,; Barcelona.

Abstract: We describe the clinical characteristics, causes and response to treatment in 6 patients with AIDS who presented with abnormal movement disorders between January 1987 and July 1993 in our hospital, 3 with hemiballismus-hemichorea, 1 with athetosis, 1 myoclonia and 1 with rubric tremor. Brain imaging showed lesions in the corpus striatum in all the patients. Suspected diagnoses were cerebral toxoplasmosis in 4, cerebral lymphoma in 1 and progressive multifocal leukoencephalopathy in 1. The toxoplasmosis patients showed improvement (2 cases) or disappearance (2 cases) of movements with antiparasitic therapy. Treatment provided no benefit to the patients with leukoencephalopathy and lymphoma. Hemiballismus-hemichorea was the most common movement disorder in AIDS patients. The underlying cause is usually lesions in the basal ganglia arising from toxoplasmosis. If the lesions are so caused, movements may improve with antiparasitic therapy.
Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS/DIAGNOSIS/ PHYSIOPATHOLOGY Adult Antiparasitic Agents/THERAPEUTIC USE Athetosis/*ETIOLOGY/PHYSIOPATHOLOGY Basal Ganglia/PHYSIOPATHOLOGY Brain/PATHOLOGY Brain Neoplasms/COMPLICATIONS/PATHOLOGY Case Report Chorea/*ETIOLOGY/PHYSIOPATHOLOGY Corpus Striatum/PHYSIOPATHOLOGY English Abstract Female Human Leukoencephalopathy, Progressive Multifocal/COMPLICATIONS Lymphoma/COMPLICATIONS/PATHOLOGY Magnetic Resonance Imaging Male Myoclonus/*ETIOLOGY/PHYSIOPATHOLOGY Toxoplasmosis/COMPLICATIONS/DRUG THERAPY/PARASITOLOGY Tremor/*ETIOLOGY/PHYSIOPATHOLOGY JOURNAL ARTICLEKWDacquiredimmunodeficiencysyndrome/KWDcomplications/diagnosis/physiopathologyadultantiparasiticagents/therapeuticuseathetosis/KWDetiology/physiopathologybasalganglia/physiopathologybrain/pathologybrainneoplasms/complications/pathologycasereportchorea/KWDetiology/physiopathologycorpusstriatum/physiopathologyenglishabstractfemalehumanleukoencephalopathy,progressivemultifocal/complicationslymphoma/complications/pathologymagneticresonanceimagingmalemyoclonus/KWDetiology/physiopathologytoxoplasmosis/complications/drugtherapy/parasitologytremor/KWDetiology/physiopathologyjournalarticle
961030
M96A1462

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