Autoimplantation technique in the treatment of anogenital warts: a clinico-immunological study. NLM AIDSLINE Important note: Information in this article was accurate in 1996. The state of the art may have changed since the publication date.

Click here to return to AIDSLINE main menu
DonateNow
Print this Article


Autoimplantation technique in the treatment of anogenital warts: a clinico-immunological study.

Int J STD AIDS. 1996 Jan-Feb;7(1):55-7. Unique Identifier : AIDSLINE MED/96228428
Usman N; Udayashankar K; Subramanian S; Thyagarajan SP; Department of Sexually Transmitted Diseases, Government Stanley; Hospital, Madras, India.

Abstract: An autoimplantation technique was adopted in the treatment of 50 cases of anogenital warts and was compared with the conventionally used podophyllin regimen in a matched group of 50 patients. They were assessed with 15 untreated subjects in a control group for the rate of clinical cure after 6 weeks, recurrence after 1 year follow up and for humoral and cell mediated immune responses before and after treatment. In the podophyllin group, 70% of patients were cured after 6 weeks while in autoimplantation, only 44% of patients were cured, and none in the control group had natural remission of warts without any treatment. After 1 year all the cured cases (100%) that completed follow up had recurrence of warts with podophyllin treatment, while none had recurrence of lesions in the autoimplantation group. Results of the humoral and cell mediated immune (CMI) response studies revealed that autoimplantation technique significantly augmented both humoral and CMI responses while there was not significant change in the immune status after podophyllin treatment (P > 0.001).
Keywords: Anus Diseases/IMMUNOLOGY/*THERAPY Comparative Study Condylomata Acuminata/IMMUNOLOGY/*THERAPY Follow-Up Studies Human Immunoglobulins/BLOOD Immunotherapy, Active/*METHODS Keratolytic Agents/*THERAPEUTIC USE Leukocyte Count Male Penile Diseases/IMMUNOLOGY/*THERAPY Podophyllin/*THERAPEUTIC USE Recurrence Treatment Outcome CLINICAL TRIAL JOURNAL ARTICLE RANDOMIZED CONTROLLED TRIALKWDanusdiseases/immunology/KWDtherapycomparativestudycondylomataacuminata/immunology/KWDtherapyfollow-upstudieshumanimmunoglobulins/bloodimmunotherapy,active/KWDmethodskeratolyticagents/KWDtherapeuticuseleukocytecountmalepenilediseases/immunology/KWDtherapypodophyllin/KWDtherapeuticuserecurrencetreatmentoutcomeclinicaltrialjournalarticlerandomizedcontrolledtrial
961030
M96A1431

Copyright © 1996 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Bristol-Myers Squibb Company, Elton John AIDS Foundation, Gill Foundation, the National Library of Medicine, Quest Diagnostics, Roche and Trimeris, and donations from users like you. Always watch for outdated information. This article first appeared in 1996. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1996. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .