Long term evaluation of septic arthritis in hemophilic patients. NLM AIDSLINE Important note: Information in this article was accurate in 1996. The state of the art may have changed since the publication date.

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Long term evaluation of septic arthritis in hemophilic patients.

Clin Orthop. 1996 Jul;(328):54-9. Unique Identifier : AIDSLINE MED/96266881
Gilbert MS; Aledort LM; Seremetis S; Needleman B; Oloumi G; Forster A; Department of Orthopedics, Mount Sinai Hospital, New York, NY,; USA.


Abstract: Before 1983, septic arthritis was rare in patients with hemophilia. With the advent of human immunodeficiency virus infection in the hemophilia population, many centers noted an increasing incidence of patients with septic arthritis. Fifteen septic joints in 10 patients with severe hemophilia were documented. Eight patients were human immunodeficiency virus positive, 1 was human immunodeficiency virus negative, and 1 was not tested. The diagnosis was delayed in 5 patients because the symptoms are similar to an acute hemarthrosis. An elevated temperature was common. The white blood cell count was elevated in only 1/3 of the infections, being modified by human immunodeficiency virus infection. Associated risk factors included infected angioaccess catheters (2), pneumonia (2), and generalized sepsis (1). All but 1 joint responded to appropriate antibiotics and either repeated aspiration or arthrotomy. However, 6 patients died of acquired immunodeficiency syndrome from 2 to 109 months after infection. Three patients are alive 29, 86, and 96 months, respectively, after infection.
Keywords: Adolescence Adult Arthritis, Infectious/*ETIOLOGY/PHYSIOPATHOLOGY Hemophilia/*COMPLICATIONS/PHYSIOPATHOLOGY Human HIV Infections/COMPLICATIONS Middle Age Range of Motion, Articular Retrospective Studies JOURNAL ARTICLEKWDadolescenceadultarthritis,infectious/KWDetiology/physiopathologyhemophilia/KWDcomplications/physiopathologyhumanhivinfections/complicationsmiddleagerangeofmotion,articularretrospectivestudiesjournalarticle
961030
M96A1381

Copyright © 1996 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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