Temporal lobe electroencephalogram power modifications during olfactory stimulation in HIV-infected patients. NLM AIDSLINE Important note: Information in this article was accurate in 1996. The state of the art may have changed since the publication date.

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Temporal lobe electroencephalogram power modifications during olfactory stimulation in HIV-infected patients.

AIDS Res Hum Retroviruses. 1996 Apr 10;12(6):547-51. Unique Identifier : AIDSLINE MED/96296967
Grassi B; Locatelli M; Lazzarin A; Scarone S; Department of Biomedical and Technological Sciences, University; of Milan Medical School, Italy.

Abstract: Evidence derived from studies concerning brain metabolism and brain electrical activity suggests that temporal lobe functioning is impaired in the course of HIV infection. To test the hypothesis of temporal lobe dysfunction in HIV infection, we utilized computerized electroencephalogram (EEG) analysis to evaluate temporal lobe EEG power modifications induced by olfactory stimulation in 10 HIV-infected patients as compared with 10 seronegative control subjects. Our findings show that HIV-infected patients respond to olfactory stimulation with an increase in temporal lobe slow electrical activity (theta EEG power), whereas control subjects show a decrease in the same activity. The theta EEG power increase during olfactory stimulation in HIV-infected patients can be interpreted as a paradoxical response of the deep temporal regions to specific procedures, supporting the hypothesis of temporal lobe dysfunction in HIV infection.
Keywords: Adult Electroencephalography/METHODS Female Human HIV Infections/*PHYSIOPATHOLOGY Male Middle Age Odors Smell/*PHYSIOLOGY Temporal Lobe/*PHYSIOPATHOLOGY CLINICAL TRIAL CONTROLLED CLINICAL TRIAL JOURNAL ARTICLEKWDadultelectroencephalography/methodsfemalehumanhivinfections/KWDphysiopathologymalemiddleageodorssmell/KWDphysiologytemporallobe/KWDphysiopathologyclinicaltrialcontrolledclinicaltrialjournalarticle
961030
M96A0705

Copyright © 1996 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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