Disseminated Penicillium marneffei infection in a patient with acquired immunodeficiency syndrome. NLM AIDSLINE Important note: Information in this article was accurate in 1996. The state of the art may have changed since the publication date.

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Disseminated Penicillium marneffei infection in a patient with acquired immunodeficiency syndrome.

J Formos Med Assoc. 1995 Sep;94(9):572-5. Unique Identifier : AIDSLINE MED/96241083
Chang CC; Liao ST; Huang WS; Liu JD; Shih LS; Department of Internal Medicine, Taipei Municipal Jen-Ai; Hospital, Taiwan.

Abstract: Penicillium marneffei is a rare human pathogen in Southeast Asia and Southern China. A 26-year-old heterosexual male had intermittent fever, diarrhea and weight loss for 3 months. He was severely immune deficient (CD4+ count, 4/microL) and serologic tests for antibodies against human immunodeficiency virus type-1 were positive. P. marneffei infection was disseminated with involvement of the liver, spleen and bone marrow. The diagnosis was established by histologic examination and confirmed by isolation of the fungus. This infection responded well to amphotericin B. He was discharged with maintenance therapy of itraconazole and continued to be stable during his 2-month follow-up.
Keywords: Adult Antifungal Agents/THERAPEUTIC USE AIDS-Related Opportunistic Infections/DIAGNOSIS/DRUG THERAPY/ *MICROBIOLOGY Case Report Hepatomegaly/MICROBIOLOGY/PATHOLOGY/RADIOGRAPHY Human Male Mycoses/DIAGNOSIS/DRUG THERAPY/*MICROBIOLOGY *Penicillium Splenomegaly/MICROBIOLOGY/PATHOLOGY/RADIOGRAPHY JOURNAL ARTICLEKWDadultantifungalagents/therapeuticuseaids-relatedopportunisticinfections/diagnosis/drugtherapy/KWDmicrobiologycasereporthepatomegaly/microbiology/pathology/radiographyhumanmalemycoses/diagnosis/drugtherapy/KWDmicrobiologyKWDpenicilliumsplenomegaly/microbiology/pathology/radiographyjournalarticle
961130
M96B1861

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