1996

Reproductive hazards: an overview of exposures to health care workers.: AAOHN J. 1995 Dec;43(12):614-21. Unique Identifier : AIDSLINE MED/96327996; Shortridge-McCauley LA; 1. Anesthetic gases, particularly nitrous oxide, have been investigated for potential reproductive, mutagenic, and carcinogenic effects. Waste gases have been found in high concentrations, even with work settings with scavenger systems in place. 2. Antineoplastic drugs, commonly used to treat persons with cancer, are
Kaposi's sarcoma in children with AIDS in Europe and the United States [letter]: Eur J Cancer. 1996 Apr;32A(4):650-1. Unique Identifier : AIDSLINE MED/96273543; Serraino D; Franceschi S
PERC: a nursing syndrome for AIDS.: Nurs Diagn. 1996 Jan-Mar;7(1):19-23. Unique Identifier : AIDSLINE MED/96335567; Coler MS; Perc is an acronym and represents a proposed nursing syndrome for people with AIDS. It incorporates the NANDA human response patterns of perceiving, exchanging, relating and choosing. These patterns were identified through a review of literature on AIDS, especially that which addressed NANDA nursing diagnoses. The ana
Nursing diagnoses for hospitalized patients with AIDS.: Nurs Diagn. 1996 Jan-Mar;7(1):9-18. Unique Identifier : AIDSLINE MED/96335566; Smith AR; Chang BL; This study examined the reliability of nursing diagnoses identified from the medical records of 100 patients hospitalized for HIV disease on a 22-bed designated unit at a large metropolitan teaching hospital in Los Angeles. The diagnoses were identified in two ways: (a) staff nurses identified 16 different nursing dia
People are more likely to have unprotected sex after negative HIV tests, survey finds [news]: Nurs Stand. 1996 Jan 3-9;10(15):10. Unique Identifier : AIDSLINE MED/96329231
No limits. AIDS and community nursing [news]: Nurs Stand. 1996 Jan 3-9;10(15):49. Unique Identifier : AIDSLINE MED/96329243
No limits. Electives: mass appeal needed.: Nurs Stand. 1996 Jan 3-9;10(15):55. Unique Identifier : AIDSLINE MED/96329248; Jones C
Risk factors for occupational HIV [news]: Nurs Stand. 1996 Jan 31;10(19):28. Unique Identifier : AIDSLINE MED/96334542
Old diseases return [news]: Nurs Stand. 1996 Mar 20;10(26):12. Unique Identifier : AIDSLINE MED/96339893; Healy P
Giving advice on sex... and safety.: Nurs Stand. 1996 Apr 3;10(28):20. Unique Identifier : AIDSLINE MED/96339927; Woolf L; Topping-Morris B
AIDS epidemic [news]: Nurs Stand. 1996 Apr 3;10(28):29. Unique Identifier : AIDSLINE MED/96339932
[Current status of the management of cytomegalovirus retinitis in patients with AIDS (editorial)]: Enferm Infecc Microbiol Clin. 1996 Mar;14(3):137-41. Unique Identifier : AIDSLINE MED/96220635; Lopez-Cortes LF; Pachon-Diaz J
[Comparison of 2 ELFA methods for the automatized diagnosis of HIV infection]: Enferm Infecc Microbiol Clin. 1996 Mar;14(3):150-4. Unique Identifier : AIDSLINE MED/96220638; Ortiz de Lejarazu R; Eiros-Bouza JM; Martinez P; Reguera JI; Rodriguez-Torres A; Departamento de Microbiologia, Facultad de Medicina, Valladolid.; BACKGROUND: Evaluate two recent tests for HIV infection diagnosis using the Enzyme-Linked Fluorescent Assay (ELFA) technique for rapid diagnosis in microbiology or virology laboratories. METHODS: A panel of 429 sera with different Ab prevalencies and different sources was prepared: 50 blood bank samples from habitual
[Rhodococcus equi pneumonia in patients with HIV infection: report of 2 cases and review of the literature]: Enferm Infecc Microbiol Clin. 1996 Mar;14(3):177-80. Unique Identifier : AIDSLINE MED/96220643; Berna JD; Garcia-Medina V; Cano A; Guirao J; Lafuente A; Garcia-Orenes MC; Servicio de Radiologia, Hospital General Universitario de; Murcia.; BACKGROUND: Pneumonia by Rhodococcus equi is infrequent and is associated with patients with important immunosuppression. To date 66 cases of pneumonia by Rhodococcus equi in patients with HIV infection have been published. The diagnosis, problems in determining diagnosis and treatment are discussed. MATERIALS AND MET
[Fatal anaphylactic shock caused by rifampicin in a patient with HIV infection (letter)]: Enferm Infecc Microbiol Clin. 1996 Mar;14(3):200-1. Unique Identifier : AIDSLINE MED/96220651; Inmaculada Rubio M; Alvarez del Vayo C; Cisneros JM; Viciana P; Martinez-Marcos F
Squamous cell carcinomas of the anus and infection with human papillomavirus in patients with AIDS.: Eur J Surg. 1996 Mar;162(3):251-3. Unique Identifier : AIDSLINE MED/96265770; Munoz-Jimenez F; Louredo-Mendez AM; Turegano-Fuentes F; del Valle-Hernandez E; Lacruz-Pelea C; Department of General Surgery, General University Hospital,; Gregorio Maranon, Madrid, Spain.
AIDS programmes at the workplace: a scoresheet for assessing the quality of services.: Occup Med (Oxf). 1996 Jun;46(3):216-20. Unique Identifier : AIDSLINE MED/96312064; London L; Department of Community Health, University of Cape Town,; Observatory, South Africa.; Little data is available on the extent or comprehensiveness of AIDS prevention activities at South African workplaces. A cross-sectional postal survey was performed of all members of the local occupational health nursing association in the area of greater Cape Town in 1994 to assess the quality of such programmes. Use
Human immunodeficiency virus (HIV) phenotype and interleukin-2/ interleukin-10 ratio are associated markers of protection and progression in HIV infection.: Blood. 1996 Jul 15;88(2):574-9. Unique Identifier : AIDSLINE MED/96289506; Clerici M; Balotta C; Salvaggio A; Riva C; Trabattoni D; Papagno L; Berlusconi A; Rusconi S; Villa ML; Moroni M; Galli M; Cattedra di Immunologia, Universita degli Studi di Milano,; Padiglione L.I.T.A., Ospedale Luigi Sacco, Italy.; Human immunodeficiency virus (HIV) isolability, rate of viral replication, HIV phenotype, type 1 and type 2 cytokine production, and CD4 counts were cross sectionally analyzed in 63 HIV seropositive (HIV+) individuals to establish possible correlations between virologic and immunologic markers of protection and progre
Apoptosis of Burkitt's lymphoma cells induced by specific interaction of surface IgM with a self-antigen: implications for lymphomagenesis in acquired immunodeficiency syndrome.: Blood. 1996 Jul 15;88(2):599-608. Unique Identifier : AIDSLINE MED/96289509; Roncella S; Cutrona G; Favre A; Ulivi M; Fais F; Signorini A; Grossi CE; Chiorazzi N; Ferrarini M; Servizi di Immunologia Clinica e Patologia Clinica, Istituto; Nazionale per la Ricerca sul Cancro-IST, Genova, Italy.; In a previous study, we described a cell line (BRG-P) derived from a woman with Burkitt s lymphoma (BL) and acquired immunodeficiency syndrome that shared the same characteristic cytogenetic abnormalities as the patient s malignant cells. This cell line contained subclones that displayed an isotype switch from IgM to
Primary effusion lymphoma: a distinct clinicopathologic entity associated with the Kaposi's sarcoma-associated herpes virus.: Blood. 1996 Jul 15;88(2):645-56. Unique Identifier : AIDSLINE MED/96289513; Nador RG; Cesarman E; Chadburn A; Dawson DB; Ansari MQ; Sald J; Knowles DM; Department of Pathology, New York Hospital-Cornell Medical; Center, New York 10021, USA.; We recently discovered the Kaposi s sarcoma-associated herpes virus (KSHV/HHV-8) in an uncommon and unusual subset of AIDS-related lymphomas that grow mainly in the body cavities as lymphomatous effusions without an identifiable contiguous tumor mass. The consistent presence of KSHV and certain other distinctive featu
Generation of primary antigen-specific human cytotoxic T lymphocytes in human/mouse radiation chimera.: Blood. 1996 Jul 15;88(2):721-30. Unique Identifier : AIDSLINE MED/96289522; Segall H; Lubin I; Marcus H; Canaan A; Reisner Y; Department of Membrane Research and Biophysics, Weizmann; Institute of Science, Rehovot, Israel.; Severe combined immunodeficient (SCID) mice are increasingly used as hosts for the adoptive transfer of human lymphocytes. Human antibody responses can be obtained in these xenogeneic chimeras, but information about the functionality of the human T cells in SCID mice is limited and controversial. Studies using human p
Recombinant human macrophage colony-stimulating factor in nonhuman primates: selective expansion of a CD16+ monocyte subset with phenotypic similarity to primate natural killer cells.: Blood. 1996 Aug 15;88(4):1215-24. Unique Identifier : AIDSLINE MED/96329554; Munn DH; Bree AG; Beall AC; Kaviani MD; Sabio H; Schaub RG; Alpaugh RK; Weiner LM; Goldman SJ; Division of Pediatric Hematology-Oncology, Medical College of; Georgia, Augusta, USA.; The CD16 receptor (Fc gamma R-III) is found on many tissue macrophages (M phi s), but its expression on circulating monocytes is restricted to a small, phenotypically distinct subset. The number of these CD16+ monocytes may be markedly increased in response to sepsis, human immunodeficiency virus infection, or metasta
Sezary syndrome T-cell clones display T-helper 2 cytokines and express the accessory factor-1 (interferon-gamma receptor beta-chain).: Blood. 1996 Aug 15;88(4):1383-9. Unique Identifier : AIDSLINE MED/96329572; Dummer R; Heald PW; Nestle FO; Ludwig E; Laine E; Hemmi S; Burg G; Department of Dermatology, University of Zurich Medical School,; Switzerland.; Sezary syndrome (SS) is a leukemic variant of low-grade cutaneous T-cell lymphomas (CTCLs). The clonal T cells in this lymphoproliferative disorder are poorly characterized. Using antibodies against the variable region of the T-cell receptor (TCR V alpha/beta), we identified four predominant T-cell clones (two V beta
A clonally distinct recurrence of Burkitt's lymphoma at 15 years.: Blood. 1996 Aug 15;88(4):1407-10. Unique Identifier : AIDSLINE MED/96329575; Lister J; Miklos JA; Swerdlow SH; Bahler DW; Department of Medicine, University of Pittsburgh School of; Medicine, PA 15213-2582, USA.; A human immunodeficiency virus-negative male was successfully treated for two occurrences of Burkitt s lymphoma, 15 years apart. As consolidation of his second remission, he underwent high-dose chemotherapy with peripheral blood stem cell transplantation. In an effort to prove whether the second lymphoma was a relapse
Boromycin, an anti-HIV antibiotic.: Biosci Biotechnol Biochem. 1996 Jun;60(6):1036-7. Unique Identifier : AIDSLINE MED/96294286; Kohno J; Kawahata T; Otake T; Morimoto M; Mori H; Ueba N; Nishio M; Kinumaki A; Komatsubara S; Kawashima K; Lead Generation Research Laboratory at Toda, Tanabe Seiyaku Co.,; Ltd., Saitama, Japan.; The polyether-macrolide antibiotic, boromycin, was isolated as a potent anti-human immunodeficiency virus (HIV) antibiotic from a fermentation broth of Streptomyces sp. A-3376. Boromycin was found to strongly inhibit the replication of the clinically isolated HIV-1 strain as well as the cultured strain in in vitro lab
Prevention of HIV infection [letter]: Acta Paediatr. 1996 Mar;85(3):280. Unique Identifier : AIDSLINE MED/96282748; Etzioni A; Pollack S; Ben-Ishai Z
Talking with elementary school-age children about AIDS and death: principles and guidelines for school nurses.: J Sch Nurs. 1996 Feb;12(1):26-32. Unique Identifier : AIDSLINE MED/96335332; Schonfeld DJ; Teaching school children about sensitive or controversial issues presents difficulties for classroom teachers as well as school nurses. At each developmental stage, there is appropriate information that can be absorbed by children that will help them in dealing with such things as death and AIDS. However, many childre
Research, language, politics, complacency and AIDS [editorial]: Contemp Nurse. 1995 Sep;4(3):94-6. Unique Identifier : AIDSLINE MED/96325780; Kerr PG
Changing attitudes.: Contemp Nurse. 1995 Dec;4(4):178-9. Unique Identifier : AIDSLINE MED/96325797; Crock E; Kleeman M
Network between main protagonists and events leading to AIDS.: Arch Med Res. 1996 Summer;27(2):107-13. Unique Identifier : AIDSLINE MED/96276731; Larralde C; Huerta L; Departamento de Immunologia, Universidad Nacional Autonoma de; Mexico, Mexico, D.F.; A definitive single hypothesis about HIV pathogenesis is still lacking in specialized literature. Rather, a picture of the extreme complexity in AIDS causality ensues from the extensive information available. This article contains an outline of the most relevant data on the subject of AIDS pathogenesis, organized into
The spectrum of HIV infection in patients seen at a private hospital in Mexico City: 115 patients seen from 1984 to 1990.: Arch Med Res. 1996 Summer;27(2):201-4. Unique Identifier : AIDSLINE MED/96276746; del Rio-Chiriboga C; Tellez-Gomez I; Orzechowski-Rallo A; Alanis-Ortega A; Section of Internal Medicine and Infectious Diseases, Hospital; Angeles del Pedregal, Mexico, D.F.; The objective of this study was to describe the epidemiology and clinical presentation of HIV infection among upper middle class patients in Mexico City. A retrospective review of outpatient and hospital records of all HIV-infected patients was accomplished by one of the authors between 1984 and 1990. A total of 115 p
Common problems with wound care: infection with HIV.: Br J Nurs. 1995 Nov 9-22;4(20):1219-23. Unique Identifier : AIDSLINE MED/96332056; Kiernan M; Young T; The issue of the care required by wounded patients infected with human immunodeficiency virus should be addressed by all nursing personnel. The virus can be transmitted through blood, blood products or wound exudate. Promotion of universal precautions should greatly minimise the risk. The patient s infection status is
Disseminated Penicillium marneffei infection in a patient with acquired immunodeficiency syndrome.: J Formos Med Assoc. 1995 Sep;94(9):572-5. Unique Identifier : AIDSLINE MED/96241083; Chang CC; Liao ST; Huang WS; Liu JD; Shih LS; Department of Internal Medicine, Taipei Municipal Jen-Ai; Hospital, Taiwan.; Penicillium marneffei is a rare human pathogen in Southeast Asia and Southern China . A 26-year-old heterosexual male had intermittent fever, diarrhea and weight loss for 3 months. He was severely immune deficient (CD4+ count, 4/microL) and serologic tests for antibodies against huma
Culture, drugs and unsafe sex: confusion about causation [editorial]: Addiction. 1996 Jun;91(6):753-8. Unique Identifier : AIDSLINE MED/96276705; Rhodes T
Ethics in nursing practice: confidentiality for women and their children with HIV/AIDS.: Medsurg Nurs. 1995 Dec;4(6):452-7. Unique Identifier : AIDSLINE MED/96335500; Pinch WJ; Dougherty CJ; McCarthy V; HIV-positive women and their children experience substantial problems brought about by the illness itself and service-delivery issues. Significant ethical concerns are raised when providing care to this patient population, and the ramifications of compromises in patient confidentiality are extremely serious. All pract
Reducing risks in blood transfusion: process and outcome.: Transfus Med. 1996 Mar;6(1):1-10. Unique Identifier : AIDSLINE MED/96265656; McClelland DB; McMenamin JJ; Moores HM; Barbara JA; Edinburgh South East Scotland Blood Transfusion Service, UK.; The last decade has seen substantial improvements in the provision of safe infection-free blood for patients in many countries. This has resulted from the combined effects of better donor education, selection, testing and exclusion processes. The residual risk of infection with HBsAg attributable to laboratory error
Behavioural risk factors for HIV infection amongst blood donors in London.: Transfus Med. 1996 Mar;6(1):31-6. Unique Identifier : AIDSLINE MED/96265659; Cowan FM; Johnson AM; Wadsworth J; Brennan M; Academic Department of Genitourinary Medicine, University College; London Medical School, UK.; This paper compares the prevalence of risk factors for sexual acquisition of human immunodeficiency virus infection (HIV-1) among blood donors with the risk in the general population. Sexual behaviour data collected as part of a cross-sectional survey of central London blood donors were compared, after indirect standa
High-performance liquid chromatographic separation of an HIV-1 reverse transcriptase inhibitor and its enantiomer.: J Chromatogr A. 1996 Jul 12;738(2):290-4. Unique Identifier : AIDSLINE MED/96314844; Wang T; Grinberg N; Bicker G; Tway P; Thompson K; Analytical Research Department, Merck Research Laboratories,; Rahway, NJ 07065-0900, USA.; This article describes the direct separation of an HIV-1 reverse transcriptase inhibitor and its enantiomer by HPLC on a silica-bonded polyacrylamide (ChiraSpher) column. The column selection was based on specific interactions between the individual enantiomers and the chiral stationary phase. The influence of some ch
[Indemnity payment: secret HIV test is the basis for claim]: Pflege Z. 1996 Jan;49(1):34-6. Unique Identifier : AIDSLINE MED/96327520; Grosskopf V
[Hospital pneumonia due to Xanthomonas maltophilia and AIDS (letter)]: Arch Bronconeumol. 1996 May;32(5):259-60. Unique Identifier : AIDSLINE MED/96265699; Sitges M; Mito O; Pedrol E
Severe complications of perianal sepsis in patients with human immunodeficiency virus.: Br J Surg. 1996 Jun;83(6):778-80. Unique Identifier : AIDSLINE MED/96334831; Consten EC; Slors JF; Danner SA; Sars PR; Obertop H; Van Lanschot JJ; Department of Surgery, Academic Medical Centre, Amsterdam, The; Netherlands.; Fifty human immunodeficiency virus (HIV)-infected patients with perianal sepsis were studied. Seven (14 per cent) had serious septic complications, four patients with severe necrotizing gangrene, and three with abscesses in the mediastinum, liver and brain respectively. CD4+ lymphocyte counts were significantly lower
Importance of human immunodeficiency virus-associated lymphadenopathy and tuberculous lymphadenitis in patients undergoing lymph node biopsy in Zambia [letter]: Br J Surg. 1996 Jun;83(6):869. Unique Identifier : AIDSLINE MED/96334858; Sarela A
Retroviral integrases and their cousins.: Curr Opin Struct Biol. 1996 Feb;6(1):76-83. Unique Identifier : AIDSLINE MED/96284114; Rice P; Craigie R; Davies DR; Laboratory of Molecular Biology,National Institute of Diabetes; and Digestive and Kidney Diseases, National Institutes of Health,; Bethesda, MD 20892-0540, USA.; The recently determined structures of the catalytic domains of HIV integrase, avian sarcoma virus integrase and the Mu transposase are strikingly similar to each other and also exhibit significant similarity to several nucleases. All these enzymes of cut polynucleotides, leaving 3 OH and 5 PO4 groups. The integrase an
Mother-to-infant transmission of hepatitis C virus in human immunodeficiency virus-coinfected mother: a case report.: J Obstet Gynaecol Res. 1996 Apr;22(2):139-42. Unique Identifier : AIDSLINE MED/96280289; Koseki S; Taga M; Aoyama M; Hirabuki T; Hirahara F; Takahasi T; Minaguchi H; Yokota S; Ito A; Department of Obstetrics and Gynecology, Yokohama City University; School of Medicine, Japan.; We report a case of vertical transmission of HCV in a mother infected with both HCV and HIV. Our case suggests that coinfection with HIV, by causing an immune dysfunction, might be one of the risk factors for the transmission of HCV.
Gastric lesions in 76 patients with adult T-cell leukemia/lymphoma. Endoscopic evaluation.: Cancer. 1996 Aug 1;78(3):396-402. Unique Identifier : AIDSLINE MED/96320566; Sakata H; Fujimoto K; Iwakiri R; Mizuguchi M; Koyama T; Sakai T; Inoue E; Tokunaga O; Shimamoto Y; Division of Gastroenterology, Department of Internal Medicine,; Saga Medical School, Saga, Japan.; BACKGROUND: Adult T-cell leukemia/lymphoma (ATLL) is caused by human T-lymphotropic virus type I. Gastric lesions in ATLL have not been described precisely, whereas the clinical features of ATLL have been well documented. The goal of the present study was to review gastric lesions, including gastric involvement, of pa
Low dose methotrexate, bleomycin, doxorubicin, cyclophosphamide, vincristine, and dexamethasone with zalcitabine in patients with acquired immunodeficiency syndrome-related lymphoma. Effect on human immunodeficiency virus and serum interleukin-6 levels over time.: Cancer. 1996 Aug 1;78(3):517-26. Unique Identifier : AIDSLINE MED/96320583; Levine AM; Tulpule A; Espina B; Boswell W; Buckley J; Rasheed S; Stain S; Parker J; Nathwani B; Gill PS; Department of Medicine, Division of Hematology, University of; Southern California School of Medicine, Los Angeles, USA.; BACKGROUND: Use of multiagent chemotherapy has been associated with complete remission (CR) in approximately 50% of patients with newly diagnosed acquired immunodeficiency syndrome (AIDS)-lymphoma, although additional AIDS-related complications may occur. Both chemotherapy and antiretroviral therapy were employed in a
The effects of 5-fluorouracil and doxorubicin on expression of human immunodeficiency virus type 1 long terminal repeat.: Cancer Lett. 1996 Aug 2;105(2):217-23. Unique Identifier : AIDSLINE MED/96319712; Panozzo J; Akan E; Griffiths TD; Woloschak GE; Center for Mechanistic Biology and Biotechnology, Argonne; National Laboratory, IL 60439-4833, USA.; Previous work by many groups has documented induction of the human immunodeficiency virus (HIV) long terminal repeat (LTR) following exposure of cells to ultraviolet light and other DNA damaging agents. Our experiments set out to determine the relative activation or repression of the HIV-LTR in response to two classes
Planned and unplanned postoperative admissions to critical care for mechanical ventilation [see comments]: Can J Anaesth. 1996 Apr;43(4):333-40. Unique Identifier : AIDSLINE MED/96282191; Rose DK; Byrick RJ; Cohen MM; Caskennette GM; Department of Anaesthesia, St. Michael's Hospital, Toronto,; Ontario.; PURPOSE: To determine which factors influence the clinician in choosing critical care admission and postoperative ventilation, we prospectively examined the incidence, timing, causes, and risk factors for admission to critical care for postoperative ventilation within 48 hr of a surgical procedure (excluding cardiac a
Peptide immunization in humans: a combined CD8+/CD4+ T cell-targeted vaccine restimulates the memory CD4 T cell response but fails to induce cytotoxic T lymphocytes (CTL).: Clin Exp Immunol. 1996 Jul;105(1):18-25. Unique Identifier : AIDSLINE MED/96280772; Brander C; Corradin G; Hasler T; Pichler WJ; Institute of Immunology and Allergology, Inselspital, Bern,; Switzerland.; Immunization with short antigenic peptides represents a potential strategy to induce peptide-specific CTL in vivo. In this study, a synthetic vaccine consisting of an HIV-derived, HLA-A2.1-binding CTL epitope and a tetanus toxin-derived T helper epitope was evaluated for its capacity to induce peptide-specific CTL in
Selective CD4+ T cell deletion after specific activation in HIV-infected individuals; protection by anti-CD28 monoclonal antibodies.: Clin Exp Immunol. 1996 Jul;105(1):31-8. Unique Identifier : AIDSLINE MED/96280774; Cottrez F; Capron A; Groux H; Unite INSERM U167, Institut Pasteur, Lille, France.; AIDS is characterized by a progressive decline in the number of CD4+ T cells. This is preceded by an early selective defect in the proliferation of these cells to recall antigens [1-3], pokeweed mitogen (PWM) [4-6] and to superantigens (SAg) [4,7]. In contrast, the proliferative response to phytohaemagglutinin (PHA) r
Complement-dependent cytotoxic antibodies to human T lymphotropic virus type I (HTLV-I)-infected cells in the sera of HTLV-I-infected individuals.: Clin Exp Immunol. 1996 Jul;105(1):39-45. Unique Identifier : AIDSLINE MED/96280775; Plotnicky-Gilquin H; Afani A; Vernant JC; Desgranges C; Unite de Recherche sur les Hepatites, INSERM U271, Lyon,; France.; To investigate whether HTLV-I induces the development of complement-dependent cytotoxic antibodies in humans, sera of asymptomatic HTLV-I carriers and of patients suffering from tropical spastic paraparesis/HTLV-I-associated myelopathy (TSP/HAM) or adult T cell leukaemia (ATL) were used in a cytotoxicity assay against
Rapidly progressive seronegative spondylarthropathy with atlantodental subluxation in a patient with moderately advanced HIV infection.: Clin Exp Rheumatol. 1996 Jan-Feb;14(1):83-5. Unique Identifier : AIDSLINE MED/96259626; Schewe CK; Kellner H; Medizinische Poliklinik, Klinikum Innenstadt, Universitat; Munchen, Germany.; It has been suggested that the immunosuppressed state associated with HIV infection may influence the clinical course of rheumatic diseases. We describe the case of a patient with moderately advanced HIV infection who developed a psoriatic rash and a rapidly progressive spondylarthropathy of the cervical spine with at
A decade of research on the natural history of HIV infection: Part 1. Markers.: Clin Invest Med. 1996 Apr;19(2):111-20. Unique Identifier : AIDSLINE MED/96260549; Strathdee SA; O'Shaughnessy MV; Montaner JS; Schechter MT; British Columbia Centre for Excellence in HIV/AIDS.; Within the context of HIV disease, a marker may be described as a consequence of disease that varies over time but does not necessarily predict future disease course. To date, the most powerful marker of HIV disease progression is the CD4 cell count. Other immunologic markers include neopterin, beta 2-microglobulin, a
A decade of research on the natural history of HIV infection: Part 2. Cofactors.: Clin Invest Med. 1996 Apr;19(2):121-30. Unique Identifier : AIDSLINE MED/96260550; Strathdee SA; Hogg RS; O'Shaughnessy MV; Montaner JS; Schechter MT; British Columbia Centre for Excellence in HIV/AIDS.; Cofactors of HIV disease may be considered risk modifiers that are causally related to future disease course. The search for potential cofactors, of viral, host or environmental origin, may provide avenues for altering the natural history of HIV infection. Potential viral cofactors include viral strains, such as syncy
Radiologic and laboratory evaluation of enhancing brain lesions in patients with AIDS.: Compr Ther. 1995 Nov;21(11):645-52. Unique Identifier : AIDSLINE MED/96238321; Johnson MD; Creasy JL; Department of Pathology, Vanderbilt University School of; Medicine, Nashville, TN 37232-2561, USA.
Chlamydia pneumoniae pneumonia in hospitalized patients. Clinical characteristics and diagnostic value of polymerase chain reaction detection in BAL.: Chest. 1996 Aug;110(2):351-6. Unique Identifier : AIDSLINE MED/96325993; Dalhoff K; Maass M; Department of Internal Medicine II, Medical University of; Luebeck, Germany.; STUDY OBJECTIVE: To evaluate the incidence and clinical characteristics of Chlamydia pneumoniae infection as detected by polymerase chain reaction (PCR) and culture of BAL in hospitalized patients with pneumonia, HIV-infected persons, and control subjects. DESIGN: Prospective, comparative clinical study. SETTING: Univ
Kaposi's sarcoma of the tip of the nose as a sentinel sign for Kaposi's sarcoma of the lung [letter]: Chest. 1996 Aug;110(2):576. Unique Identifier : AIDSLINE MED/96326035; Masih RB; Jesudass SW; Verghese A
[Effects of thymectomy and glucocorticoid therapy on peripheral lymphocytes in myasthenia gravis]: Chung Hua Nei Ko Tsa Chih. 1995 Aug;34(8):514-7. Unique Identifier : AIDSLINE MED/96329747; Huang Y; Xu X; Lin J; Peking Union Medical College Hospital, Beijing.; Clinical manifestations and peripheral blood lymphocyte subset changes were studied in patients with myasthenia gravis (MG) to elucidate the mechanism of clinical improvement following treatment, with thymectomy (Tx) or glucocorticoid (GC) therapy. The changes found were: 1. There was a significant increase in percent
[Expression of adhesion molecules on lymphocyte in patients with systemic lupus erythematosus]: Chung Hua Nei Ko Tsa Chih. 1995 Aug;34(8):545-7. Unique Identifier : AIDSLINE MED/96329755; Zhou T; Jiang Y; Yao J; Ruijin Hospital, Shanghai Second Medical University.; Peripheral blood lymphocyte phenotype (CD3, CD4, CD8, CD20, CD45RA and CD45RO) and adhesion molecule phenotype (CD11a/LFA-1 alpha, CD18/LFA-1 beta and CD54/ICAM-1) were investigated in 35 patients with systemic lupus erythematosus (SLE) by using flow cytometric analysis and dual immunofluorescence staining method. Res
Individual and situational markers of condom use and sex with nonprimary partners among alcoholic inpatients: findings from the ATRISK Study.: Health Psychol. 1996 May;15(3):185-92. Unique Identifier : AIDSLINE MED/96336123; Scheidt DM; Windle M; Research Institute on Addictions, Buffalo, New York, USA.; dscheidt@acspr1.acs.brockport.edu; Alcoholics in treatment have demonstrated increased rates of HIV risk behavior and infection. This study explored individual and situational variables associated with HIV risk behaviors such as condom nonuse and sex with nonprimary partners reported during structured interviews of 802 male and female alcoholic inpatie
Applications of the monitoring process model to coping with severe long-term medical threats.: Health Psychol. 1996 May;15(3):216-25. Unique Identifier : AIDSLINE MED/96336127; Miller SM; Rodoletz M; Mangan CE; Schroeder CM; Sedlacek TV; Division of Population Science, Fox Chase Cancer Center,; Philadelphia, Pennsylvania 19107, USA. sm.miller@fccc.edu; Guided by the monitoring process model (MPM), the authors explored the illness responses of 2 samples: high monitors (who are cognitively vigilant to and amplify threat-related cues) and low monitors (who avoid them and blunt their impact). Both samples-101 women with human papillomavirus-related precancerous cervical
The solution structure of the bovine leukaemia virus matrix protein and similarity with lentiviral matrix proteins.: EMBO J. 1996 Jul 1;15(13):3267-74. Unique Identifier : AIDSLINE PDB; Matthews S; Mikhailov M; Burny A; Roy P; Department of Biochemistry, Imperial College of Science,; Technology and Medicine, University of London, UK.; sjm@bioch.ox.ac.uk; In the mature virion, retroviral matrix proteins are found in association with the inner face of the viral membrane. They play a critical role in determining the morphogenesis of virus assembly. We have determined the three-dimensional solution structure of the bovine leukaemia virus (BLV) matrix protein by heteronucl
Identification of AIDS-related tuberculosis with concordant gallium-67 and three-hour delayed thallium-201 scintigraphy.: Eur J Nucl Med. 1996 Jul;23(7):852-4. Unique Identifier : AIDSLINE MED/96269981; Gomez MV; Gallardo FG; Cobo J; Babe J; Servicio de Medicina Nuclear, Instituto de Salud Carlos III,; Madrid, Spain.; Concordant gallium-67 and thallium-201 uptake has been described in malignant lesions. More recently, 201Tl accumulation has been described in some benign conditions. The authors report three HIV-positive patients who underwent 67Ga and 201Tl scintigraphy. These studies revealed concordant 67Ga and 201Tl uptake and tu
Chronic unexplained diarrhea in human immunodeficiency virus infection: determination of the best diagnostic approach [letter]: Gastroenterology. 1996 Jul;111(1):269-71. Unique Identifier : AIDSLINE MED/96315578; Simon D; Kotler DP; Brandt LJ
[Comparative study of the placenta from HIV+ mothers. Ultrastructural analysis]: Ginecol Obstet Mex. 1996 Apr;64:167-76. Unique Identifier : AIDSLINE MED/96233329; Villegas-Castrejon H; Paredes-Vivas Y; Flores-Rivera E; Gorbea-Robles MC; Arredondo-Garcia JL; Instituto Nacional de Perinatologia, Mexico, D.F.; Perinatal vertical transmission has increased in all the world; it is considered that at the present time there are about one million of children with HIV. Variation goes from 12 to 40%, at different countries. During the last years antiretroviral drugs as
Meeting the social service needs of persons with AIDS: hospices' response.: Hosp J. 1995;10(4):49-65. Unique Identifier : AIDSLINE MED/96329978; Kovacs PJ; Rodgers AY; A national sample of 148 directors of hospice social service departments (or persons most familiar with the delivery of social services in the hospice) participated in an exploratory study investigating the effects of the acquired immune deficiency syndrome (AIDS) epidemic on the delivery of hospice social services. F
Neuropathology of human immunodeficiency virus: questions and answers [editorial]: Hum Pathol. 1996 Jul;27(7):623-4. Unique Identifier : AIDSLINE MED/96320623; Petito CK
Neuropathology of human immunodeficiency virus infection at different disease stages.: Hum Pathol. 1996 Jul;27(7):637-42. Unique Identifier : AIDSLINE MED/96320626; Kibayashi K; Mastri AR; Hirsch CS; Office of Chief Medical Examiner of the City of New York, NY; 10016-6402, USA.; The authors studied the brains of 471 adults infected with human immunodeficiency virus type 1 (HIV-1): 123 asymptomatic carriers, 127 in an early stage of acquired immunodeficiency syndrome (AIDS) with pulmonary tuberculosis or bacterial infections, and 221 in fully developed AIDS with opportunistic infections or neo
Distribution of transforming growth factor-beta isoforms in human immunodeficiency virus-1 encephalitis.: Hum Pathol. 1996 Jul;27(7):643-9. Unique Identifier : AIDSLINE MED/96320627; Johnson MD; Gold LI; Department of Pathology, Vanderbilt Medical School, Nashville, TN; 37232, USA.; The transforming growth factor-beta family of polypeptides includes three related isoforms with pervasive effects on immune system function. In this study, the authors evaluated human brains with human immunodeficiency virus (HIV)-1 encephalitis for transforming growth factor beta (TGFbeta)1, TGFbeta2, and TGFbeta3 im
Crusted (Norwegian) scabies in a specialist HIV unit: successful use of ivermectin and failure to prevent nosocomial transmission.: Genitourin Med. 1996 Apr;72(2):115-7. Unique Identifier : AIDSLINE MED/96273399; Corbett EL; Crossley I; Holton J; Levell N; Miller R; De Cock KM; HIV/AIDS Unit Camden & Islington Community Health Services NHS; Trust, Middlesex Hospital, London, UK.; A nosocomial outbreak of scabies in a specialist inpatient HIV unit resulted from a patient admitted with crusted scabies. Treatment of his infestation with topical scabicides alone failed and he remained infectious for several weeks. His infestation was then eradicated with combined topical treatment and oral ivermec
Hepatitis C virus infection in a large cohort of homosexually active men: independent associations with HIV-1 infection and injecting drug use but not sexual behaviour.: Genitourin Med. 1996 Apr;72(2):118-22. Unique Identifier : AIDSLINE MED/96273400; Bodsworth NJ; Cunningham P; Kaldor J; Donovan B; Taylor Square Private Clinic, Darlinghurst, New South Wales,; Australia.; OBJECTIVE: To determine the prevalence and risk factors for hepatitis C virus (HCV) infection in a cohort of homosexually active men, with particular reference to assessing sexual transmission. DESIGN: Prevalence based on cross-sectional testing for HCV (c100 protein) antibody in a cohort using sera stored between 198
Changes in heterosexual university undergraduates' HIV-related knowledge, attitudes and behaviour: Melbourne, 1989-1994.: Genitourin Med. 1996 Apr;72(2):123-7. Unique Identifier : AIDSLINE MED/96273401; Rosenthal DA; Smith AM; Reichler H; Moore S; Centre for the Study of Sexually Transmissible Diseases, LaTrobe; University, Carlton South, Australia.; OBJECTIVE: To examine differences in the AIDS-related knowledge, attitudes and behaviours of first year university undergraduates in 1989 and 1994. DESIGN: Comparisons were made between cross-sectional surveys, conducted in 1989 and 1994, of first year undergraduates at three Melbourne universities. RESULTS: The 1994
Epidemiology of cryptosporidiosis among European AIDS patients.: Genitourin Med. 1996 Apr;72(2):128-31. Unique Identifier : AIDSLINE MED/96273402; Pedersen C; Danner S; Lazzarin A; Glauser MP; Weber R; Katlama C; Barton SE; Lundgren JD; Department of Infectious Diseases, Hvidovre Hospital, Denmark.; OBJECTIVE: To study epidemiology and possible risk factors associated with the development of cryptosporidiosis among European patients with AIDS. METHODS: An inception cohort of 6548 patients with AIDS, consecutively diagnosed from 1979 to 1989, from 52 centres in 17 European countries was studied. Data on all AIDS d
Disseminated Toxoplasma gondii infection presenting with a fulminant pneumonia [clinical conference]: Genitourin Med. 1996 Apr;72(2):139-43. Unique Identifier : AIDSLINE MED/96273406; Miller RF; Lucas SB; Bateman NT; Department of Academic Genitourinary Medicine, University College; London Medical School, UK.
Should screening of genital infections be part of antenatal care in areas of high HIV prevalence? [letter]: Genitourin Med. 1996 Apr;72(2):148. Unique Identifier : AIDSLINE MED/96273412; L'Herminez M; L'Herminez R; Holtby I
Syndromic management of genital ulcer disease--a critical appraisal [letter]: Genitourin Med. 1996 Apr;72(2):148. Unique Identifier : AIDSLINE MED/96273411; Bhargava R; Mathur D; Bhargava P
Sexually transmitted diseases control in developing countries.: Genitourin Med. 1996 Apr;72(2):83-8. Unique Identifier : AIDSLINE MED/96273392; Adler MW; Academic Department of Genitourinary Medicine, Mortimer Market; Centre, London, UK.; Sexually transmitted diseases (STDs) are a major public health problem now compounded by the advent of AIDS and HIV infection. The size of the problem represented by STDs and HIV is unknown however it is estimated that there are 333 million new cases of STD per annum and currently 15-20 million people infected worldwi
Prevention and management of tuberculosis in HIV positive patients living in countries with a low prevalence of Mycobacterium tuberculosis.: Genitourin Med. 1996 Apr;72(2):89-92. Unique Identifier : AIDSLINE MED/96273393; Brook MG; Miller RF; Department of Medicine, Camden & Islington Community Health; Services NHS Trust, London, UK.; We have re-examined the evidence on which current British Thoracic Society recommendations for primary and secondary prophylaxis and therapy of tuberculosis are based. We suggest that in a country such as the UK with a low prevalence of tuberculosis, primary prophylaxis should be offered primarily to tuberculin positi
Induction of single and dual cytotoxic T-lymphocyte responses to viral proteins in mice using recombinant hybrid Ty-virus-like particles.: Immunology. 1996 Feb;87(2):171-8. Unique Identifier : AIDSLINE MED/96245967; Layton GT; Harris SJ; Myhan J; West D; Gotch F; Hill-Perkins M; Cole JS; Meyers N; Woodrow S; French TJ; Adams SE; Kingsman AJ; British Biotech Pharmaceuticals Ltd, Oxford, UK.; The induction of cytotoxic T-lymphocyte (CTL) responses to viral proteins is thought to be an essential component of protective immunity against viral infections. Methods for generating such responses in a reproducible manner would be of great value in vaccine development. We demonstrate here that the recombinant anti
Expression of L-selectin (CD62L) discriminates Th1- and Th2-like cytokine-producing memory CD4+ T cells.: Immunology. 1996 Feb;87(2):186-90. Unique Identifier : AIDSLINE MED/96245969; Kanegane H; Kasahara Y; Niida Y; Yachie A; Sughii S; Takatsu K; Taniguchi N; Miyawaki T; Department of Pediatrics, School of Medicine, Kanazawa; University, Japan.; Human memory (CD45RO+) CD4+ T cells can be distinguished into two subpopulations on the basis of expression of the lymph node homing receptor, L-selectin (CD62L). In a prior study we showed that human L-selectin-positive memory T-helper (Th) cells promote the maturation of IgG- and IgA-producing cells by naive B cells
T-cell-receptor dose and the time of treatment during murine retrovirus infection for maintenance of immune function.: Immunology. 1996 Feb;87(2):198-204. Unique Identifier : AIDSLINE MED/96245971; Liang B; Ardestani S; Marchalonis JJ; Watson RR; Department of Family and Community Medicine, University of; Arizona, Tucson 85724, USA.; C57BL/6 mice were injected with different doses of human T-cell receptor (TCR) V beta 8.1 CDR1 peptide at different times after murine retrovirus (LP-BM5) infection. Injection with TCR V beta 8.1 CDR1 peptide largely prevented the retrovirus-induced reduction in B- and T-cell proliferation, and T-helper 1 (Th1) cytoki
CD8-deficient mice exhibit augmented mucosal immune responses and intact adjuvant effects to cholera toxin.: Immunology. 1996 Feb;87(2):220-9. Unique Identifier : AIDSLINE MED/96245974; Hornquist E; Grdic D; Mak T; Lycke N; Department of Medical Microbiology and Immunology, University of; Goteborg, Sweden.; We used normal, CD4 and CD8 gene-targeted mice to investigate the role of CD4+ and CD8+ T cells in the regulation of gut mucosal immune responses following oral immunizations with cholera toxin (CT) adjuvant. Phenotypic analysis of mucosa-associated tissues revealed normal CD3+ T-cell frequencies in CD4-/- and CD8-/-
Dynamic changes in circulating and antigen-responsive T-cell subpopulations post-Mycobacterium bovis infection in cattle.: Immunology. 1996 Feb;87(2):236-41. Unique Identifier : AIDSLINE MED/96245976; Pollock JM; Pollock DA; Campbell DG; Girvin RM; Crockard AD; Neill SD; Mackie DP; Veterinary Sciences Division, Department of Agriculture for; Northern Ireland, Stormont, Belfast.; Bovine tuberculosis is a threat to animal and human health in several countries. Greater understanding of the immunology of the disease is required to develop improved tests and vaccines. This study has used a model of bovine tuberculosis, established in the natural host, to investigate the dynamic changes that occur
Impaired immunity and altered pulmonary responses in mice with a disrupted interferon-gamma receptor gene exposed to the irradiated Schistosoma mansoni vaccine.: Immunology. 1996 Feb;87(2):275-82. Unique Identifier : AIDSLINE MED/96245982; Wilson RA; Coulson PS; Betts C; Dowling MA; Smythies LE; Department of Biology, University of York, UK.; A high level of protection against Schistosoma mansoni is elicited in mice by the irradiated cercaria vaccine and interferon-gamma (IFN-gamma) is a key cytokine in the pulmonary effector response. The role of this cytokine has been investigated in mice with a targeted disruption of the IFN-gamma receptor gene (IFN-gam
Cultured human Langerhans' cells are superior to fresh cells at presenting native HIV-1 protein antigens to specific CD4+ T-cell lines.: Immunology. 1996 Feb;87(2):310-6. Unique Identifier : AIDSLINE MED/96245987; Girolomoni G; Valle MT; Zacchi V; Costa MG; Giannetti A; Manca F; Istituto Dermopatico dell'Immacolata, IRCCS, Rome, Italy.; Cultured Langerhans cells (CLC) exhibit enhanced antigen-presenting function compared to freshly isolated LC (FLC), but they are commonly believed to be inefficient at processing intact proteins. In this study, FLC and CLC from normal, human immunodeficiency virus (HIV) seronegative volunteers were compared for their
Characterization of T cells that confer a high degree of protective immunity against tuberculosis in mice after vaccination with tumor cells expressing mycobacterial hsp65.: Infect Immun. 1996 Jul;64(7):2400-7. Unique Identifier : AIDSLINE MED/96294743; Silva CL; Silva MF; Pietro RC; Lowrie DB; Department of Parasitology, Microbiology and Immunology, School; of Medicine of Ribeirao Preto, University of Sao Paulo, Brazil.; Mice vaccinated by injection with tumor cells expressing the Mycobacterium leprae gene for hsp65 acquire a remarkably high degree of protection against challenge with Mycobacterium tuberculosis. We used limiting-dilution analysis to assess the frequency of CD4+ CD8- and CD4- CD8+ splenocytes responding to mycobacteria
Melanin, melanin ghosts, and melanin composition in Cryptococcus neoformans.: Infect Immun. 1996 Jul;64(7):2420-4. Unique Identifier : AIDSLINE MED/96294746; Wang Y; Aisen P; Casadevall A; Department of Microbiology and Immunology, Albert Einstein; College of Medicine, Bronx, New York 10461, USA.; Melanin synthesis is associated with virulence for the pathogenic fungus Cryptococcus neoformans. Exposure of nonmelanized C. neoformans 4067 cells to 4 M guanidinium isothiocyanate followed by 6 M HCl at 100 degrees C resulted in complete solubilization of cellular structures. However, exposure of melanized C. neofor
Immunity to Cryptosporidium muris infection in mice is expressed through gut CD4+ intraepithelial lymphocytes.: Infect Immun. 1996 Jul;64(7):2556-62. Unique Identifier : AIDSLINE MED/96294764; McDonald V; Robinson HA; Kelly JP; Bancroft GJ; Department of Clinical Sciences, London School of Hygiene and; Tropical Medicine, London, United Kingdom.; The role of gut intraepithelial lymphocytes (IEL) in immunity to cryptosporidial infection was investigated with a murine infection model involving Cryptosporidium muris. Oocyst shedding was monitored in severe combined immunodeficiency (SCID) mice infected with C. muris following intravenous injection of mesenteric l
Tumor necrosis factor alpha and interleukin-12 contribute to resistance to the intracellular bacterium Brucella abortus by different mechanisms.: Infect Immun. 1996 Jul;64(7):2782-6. Unique Identifier : AIDSLINE MED/96294793; Zhan Y; Liu Z; Cheers C; Department of Microbiology, University of Melbourne, Parkville,; Victoria, Australia.; Both interleukin-12 (IL-12) and tumor necrosis factor alpha (TNF-alpha) are produced early in intracellular bacterial infection. Depletion of either IL-12 or TNF-alpha by a single injection of specific antibody 4 h before the injection of Brucella abortus 19 led to the exacerbation of infection 2 weeks later. Whereas
Colocalisation of human immunodeficiency virus and human cytomegalovirus infection in brain autopsy tissue from AIDS patients.: Ir J Med Sci. 1996 Apr-Jun;165(2):133-8. Unique Identifier : AIDSLINE MED/96293026; Balluz IM; Farrell MA; Kay E; Staunton MJ; Keating JN; Sheils O; Cosby SL; Mabruk MJ; Sheahan BJ; Atkins GJ; Department of Microbiology, Moyne Institute of Preventive; Medicine, Trinity College, Dublin, Northern Ireland.; We have examined 26 human AIDS brains obtained at post mortem for infection by human immunodeficiency virus (HIV) and human cytomegalovirus (HCMV), and for dual infection of cells by both viruses. The techniques used were enzyme-linked immunocytochemistry for HCMV and in situ hybri
Interviews with home health aides caring for people with AIDS [interview]: Home Healthc Nurse. 1995 Nov-Dec;13(6):20-4. Unique Identifier : AIDSLINE MED/96329954; Beschle JC; Beggs CM; Russell GE; Through a phenomenological perspective, this study describes the experiences of home health aides caring for people with acquired immunodeficiency syndrome. Six home health aides were asked the question, What is it like to be a home health aide caring for persons with acquired immunodeficiency syndrome? The essential
Kinetic characterization of human immunodeficiency virus type-1 protease-resistant variants.: J Biol Chem. 1996 Jul 26;271(30):17979-85. Unique Identifier : AIDSLINE MED/96279343; Pazhanisamy S; Stuver CM; Cullinan AB; Margolin N; Rao BG; Livingston DJ; Vertex Pharmaceuticals Incorporated, Cambridge, Massachusetts; 02139, USA.; Passage of human immunodeficiency virus type-1 (HIV-1) in T-lymphocyte cell lines in the presence of increasing concentrations of the hydroxylethylamino sulfonamide inhibitor VX-478 or VB-11328 results in sequential accumulation of mutations in HIV-1 protease. We have characterized recombinant HIV-1 proteases that con
A synthetic conformational epitope from the C4 domain of HIV Gp120 that binds CD4.: J Biol Chem. 1996 Jul 26;271(30):17990-5. Unique Identifier : AIDSLINE MED/96279345; Robey FA; Harris-Kelson T; Robert-Guroff M; Batinic D; Ivanov B; Lewis MS; Roller PP; Peptide and Immunochemistry Unit, NIDR, National Institutes of; Health Bethesda, Maryland 20892, USA.; The fourth conserved domain of the human immunodeficiency virus type 1 (HIV-1) envelope, the C4 region of glycoprotein 120 (gp120), is believed to be a major part of gp120 that is necessary for binding to CD4. Recently, we found that C4 in gp120 is probably an alpha-helix, because antibodies made against helical const
A20 blocks endothelial cell activation through a NF-kappaB-dependent mechanism.: J Biol Chem. 1996 Jul 26;271(30):18068-73. Unique Identifier : AIDSLINE MED/96279354; Cooper JT; Stroka DM; Brostjan C; Palmetshofer A; Bach FH; Ferran C; Sandoz Center for Immunobiology, Deaconess Hospital, Harvard; Medical School, Boston, Massachusetts 02215, USA.; The A20 gene product is a novel zinc finger protein originally described as a tumor necrosis factor alpha (TNF)-inducible early response gene in human umbilical vein endothelial cells (HUVEC). Its described function is to block TNF-induced apoptosis in fibroblasts and B lymphocytes, but more recently it has also been
Analysis of T cell receptor V beta expression in rabbit T lymphocytes induced to proliferate by an HTLV-I-transformed leukemogenic T cell line.: J Cancer Res Clin Oncol. 1996;122(8):458-64. Unique Identifier : AIDSLINE MED/96328340; Isono T; Isegawa Y; Seto A; Department of Microbiology, Shiga University of Medical Science,; Japan.; Peripheral blood lymphocytes (PBL) from rabbits of the Chbb:HM strain proliferated in coculture with an X-ray-irradiated HTLV-I-transformed leukemogenic cell line of (B/J x Chbb:HM) F1 origin, whereas PBL from rabbits of the B/J and F1 strains hardly proliferated at all in co-culture with the same cell line. A provira
Activation of antigen-induced lymphocyte proliferation by interleukin-15 without the mitogenic effect of interleukin-2 that may induce human immunodeficiency virus-1 expression.: J Clin Invest. 1996 Aug 1;98(3):616-21. Unique Identifier : AIDSLINE MED/96326385; Patki AH; Quinones-Mateu ME; Dorazio D; Yen-Lieberman B; Boom WH; Thomas EK; Lederman MM; Department of Medicine, Case Western Reserve University School of; Medicine, University Hospitals of Cleveland, Ohio 44106, USA.; The newly identified cytokine, IL-15 enhanced antigen-induced proliferation of PBMC obtained from HIV-1-seropositive subjects. When compared to IL-2 which enhanced both spontaneous and antigen-induced lymphocyte proliferative responses, IL-15 rarely increased spontaneo
Pathogenic and protective correlates of T cell proliferation in AIDS. HNRC Group. HIV Neurobehavioral Research Center.: J Clin Invest. 1996 Aug 1;98(3):731-40. Unique Identifier : AIDSLINE MED/96326399; Schrier RD; Wiley CA; Spina C; McCutchan JA; Grant I; Department of Pathology, University of California, San Diego, La; Jolla 92093, USA. rschrier@ucsd.edu; To investigate the association of antigen specific CD4 T cell activation with HIV disease progression and AIDS-related central nervous system damage, T cell proliferation responses to HIV, CMV , and HSV were evaluated in infected individuals. CD4 T cell loss and
Widespread cutaneous bacillary angiomatosis and a large fungating mass in an HIV-positive man.: J Am Acad Dermatol. 1996 Aug;35(2 Pt 2):285-7. Unique Identifier : AIDSLINE MED/96319544; Fagan WA; DeCamp NC; Kraus EW; Pulitzer DR; University of Texas Health Science Center, Division of; Dermatology, San Antonio 78284-7876, USA.; Bacillary angiomatosis (BA), an infection caused by a gram-negative rod, can be a multiorgan disease. The usual causative organism, Bartonella (formerly Rochalimaea) hensalae, has only recently been identified. Bartonella quintana has also been shown to cause some cases of cutaneous BA. We describe a patient with wide
Photoaccentuated erythroderma associated with CD4+ T lymphocytopenia: successful treatment with 5-methoxypsoralen and UVA, interferon alfa-2b, and extracorporeal photopheresis.: J Am Acad Dermatol. 1996 Aug;35(2 Pt 2):291-4. Unique Identifier : AIDSLINE MED/96319546; Wolf P; Mullegger R; Cerroni L; Aigner R; Fueger G; Hofler G; Derbaschnig J; Kerl H; Department of Dermatology, Karl Franzens University, Graz,; Austria.; We describe a 53-year-old HIV-negative white man who had chronic CD4+ T lymphocytopenia and photoaccentuated erythroderma with lymphoma-like histologic changes. The erythroderma completely responded to 5-methoxypsoralen and UVA (PUVA), interferon alfa-2b, and extracorporeal photopheresis. During therapy opportunistic
Leishmaniasis presenting as a dermatomyositis-like eruption in AIDS.: J Am Acad Dermatol. 1996 Aug;35(2 Pt 2):316-9. Unique Identifier : AIDSLINE MED/96319553; Dauden E; Penas PF; Rios L; Jimenez M; Fraga J; Alvar J; Garcia-Diez A; Department of Dermatology, Hospital de la Princesa, Universidad; Autonoma, Madrid, Spain.; Three patients are described with leishmaniasis and AIDS, with cutaneous lesions mimicking dermatomyositis. Leishmania organisms were observed in great numbers in the dermis of lesional skin biopsy specimens. They were also present inside keratinocytes in all layers of the epidermis in one patient. Skin cultures from
Those who have will, those who haven't won't: caring for HIV-positive patients.: J Contin Educ Nurs. 1996 Mar-Apr;27(2):80-4. Unique Identifier : AIDSLINE MED/96329987; Dols CL; Bradley-Magnuson L; Nurses willingness to care for HIV-positive patients continues to be an issue since the inception of the HIV pandemic. This descriptive correlational study found that while nurses fear of contagion has decreased their willingness to care has not increased in the same proportion. Furthermore, while formal education d
Fever in patients with HIV infection.: Infect Dis Clin North Am. 1996 Mar;10(1):149-65. Unique Identifier : AIDSLINE MED/96244917; Sullivan M; Feinberg J; Bartlett JG; Johns Hopkins University School of Medicine, Baltimore, Maryland,; USA.; Fever is a common sign during the course of HIV infection, usually represents a superimposed opportunistic infection, and is almost always a treatable condition. Proper management generally requires detection of the underlying cause, and the diagnostic evaluation is largely driven by the clinical symptoms, associated
Construction of recombinant extended single-chain antibody peptide conjugates for use in the diagnosis of HIV-1 and HIV-2.: J Immunol Methods. 1996 Jun 10;192(1-2):13-23. Unique Identifier : AIDSLINE MED/96269541; Coia G; Hudson PJ; Lilley GG; CSIRO Division of Biomolecular Engineering, Parkville, Australia.; The construction, expression and evaluation of recombinant scFv based HIV diagnostic reagents are described. In a whole-blood, erythrocyte agglutination assay format, recombinant scFv antibodies (expressed in Escherichia coli), linked to a spacer domain and HIV-gp36 or -gp41 peptides, were shown to be able to detect e
A fluorescent in situ hybridization method in flow cytometry to detect HIV-1 specific RNA.: J Immunol Methods. 1996 Jun 21;193(2):167-76. Unique Identifier : AIDSLINE MED/96269536; Borzi RM; Piacentini A; Monaco MC; Lisignoli G; Degrassi A; Cattini L; Santi S; Facchini A; Laboratorio di Immunologia e Genetica, Istituto di Ricerca; Codivilla Putti, I.O.R., Bologna, Italy.; In HIV+ patients, the presence of HIV-RNA in plasma and circulating cells has been reported to be a marker of progression but the percentage of transcriptionally active infected cells remains unclear. We have developed a reliable fluorescent in situ hybridization method for the detection of HIV specific RNA by flow cy
Present-day management of pulmonary tuberculosis.: J Indian Med Assoc. 1995 Apr;93(4):144-8. Unique Identifier : AIDSLINE MED/96319858; Kundu AK; Kundu AK; Department of Medicine, NRS Medical College, Calcutta.
Detection of human herpesvirus 8 DNA sequences before the appearance of Kaposi's sarcoma in human immunodeficiency virus (HIV)-positive subjects with a known date of HIV seroconversion.: J Infect Dis. 1996 Aug;174(2):283-7. Unique Identifier : AIDSLINE MED/96313003; Lefrere JJ; Meyohas MC; Mariotti M; Meynard JL; Thauvin M; Frottier J; Institut National de Transfusion Sanguine and Service des; Maladies, Infectieuses, Hopital Saint-Antoine, Paris, France.; The presence of human herpesvirus 8 (HHV-8) DNA sequences was sought by polymerase chain reaction (PCR) in peripheral blood mononuclear cells of 4 groups: 6 human immunodeficiency virus (HIV)-infected persons with well-defined dates of seroconversion, during the period between the diagnosis of HIV infection and the ap
Virologic markers of human immunodeficiency virus type 1 in cerebrospinal fluid of infected children.: J Infect Dis. 1996 Aug;174(2):288-93. Unique Identifier : AIDSLINE MED/96313004; Pratt RD; Nichols S; McKinney N; Kwok S; Dankner WM; Spector SA; Department of Pediatrics, University of California, San Diego, La; Jolla 92093-0672, USA.; To identify virologic correlates associated with central nervous system (CNS) abnormalities in children infected with human immunodeficiency virus type 1 (HIV-1), cerebrospinal fluid (CSF) was examined for virologic markers and correlated with neurodevelopmental status and neuroimaging abnormalities. Of 30 children, 1
Predictive markers of AIDS dementia complex: CD4 cell count and cerebrospinal fluid concentrations of beta 2-microglobulin and neopterin.: J Infect Dis. 1996 Aug;174(2):294-8. Unique Identifier : AIDSLINE MED/96313005; Brew BJ; Dunbar N; Pemberton L; Kaldor J; Department of Neurology, St. Vincent's Hospital, Sydney,; Australia.; A predictive marker for AIDS dementia complex (ADC) in a cohort of neurologically asymptomatic human immunodeficiency virus type 1 (HIV-1)-infected patients with
The effect of latent Mycobacterium tuberculosis infection on human immunodeficiency virus (HIV) disease progression and HIV RNA load among injecting drug users.: J Infect Dis. 1996 Aug;174(2):299-308. Unique Identifier : AIDSLINE MED/96313006; Manoff SB; Farzadegan H; Munoz A; Astemborski JA; Vlahov D; Rizzo RT; Solomon L; Graham NM; Department of Epidemiology, Johns Hopkins University School of; Hygiene and Public Health, Baltimore, Maryland 21205, USA.; To examine the relationship between latent Mycobacterium tuberculosis infection and human immunodeficiency virus (HIV) disease progression, two studies were done among a cohort of HIV-infected injecting drug users. First, the decline in CD4 cell count after baseline tuberculin skin testing was prospectively compared f
An international collaborative study of the effects of coinfection with human T-lymphotropic virus type II on human immunodeficiency virus type 1 disease progression in injection drug users.: J Infect Dis. 1996 Aug;174(2):309-17. Unique Identifier : AIDSLINE MED/96313007; Hershow RC; Galai N; Fukuda K; Graber J; Vlahov D; Rezza G; Klein RS; Des Jarlais DC; Vitek C; Khabbaz R; Freels S; Zuckerman R; Pezzotti P; Kaplan JE; University of Illinois, Chicago College of Medicine and School of; Public Health 60612, USA.; To determine whether human T-lymphotropic virus (HTLV) type II coinfection affects progression of human immunodeficiency virus type 1 (HIV) infection, longitudinal data on 370 HIV-infected injection drug users (IDUs) with known HIV seroconversion dates from four cohort studies were pooled. HTLV infection was determine
Human T lymphocyte virus type I-induced myeloneuropathy in rats: implication of local activation of the pX and tumor necrosis factor-alpha genes in pathogenesis.: J Infect Dis. 1996 Aug;174(2):318-23. Unique Identifier : AIDSLINE MED/96313008; Tomaru U; Ikeda H; Ohya O; Abe M; Kasai T; Yamasita I; Morita K; Wakisaka A; Yoshiki T; Department of Pathology, Hokkaido University School of Medicine; Sapporo, Japan.; The pathogenetic roles of human T lymphocyte virus type I (HTLV-I) and cytokines were investigated in HTLV-I-induced myeloneuropathy in Wistar-King-Aptekman-Hokudai rats. In the nervous system, pX messenger RNAs of HTLV-I were selectively expressed in the diseased spinal cord and peripheral nerves but not in the unaff
Immunoregulation in onchocerciasis: persons with ocular inflammatory disease produce a Th2-like response to Onchocerca volvulus antigen.: J Infect Dis. 1996 Aug;174(2):380-6. Unique Identifier : AIDSLINE MED/96313017; Plier DA; Awadzi K; Freedman DO; Department of Medicine, University of Alabama at Birmingham; 35294-2170, USA.; To examine the role of specific cytokines in mediating the clinical manifestations of human onchocercal disease, microfilariae-positive Ghanaian subjects with inflammatory ocular disease were compared with microfilariae-positive subjects without ocular disease. Onchocerca volvulus antigen (OvAg)-stimulated peripheral
Once-weekly intraocular injections of ganciclovir for maintenance therapy of cytomegalovirus retinitis: clinical and ocular outcome.: J Infect Dis. 1996 Aug;174(2):393-6. Unique Identifier : AIDSLINE MED/96313019; Hodge WG; Lalonde RG; Sampalis J; Deschenes J; Department of Ophthalmology, McGill AIDS Centre, McGill; University, Montreal, Canada.; The clinical course and the outcome of treatment were studied in 40 patients with primary cytomegalovirus ( CMV ) retinitis in 57 eyes. All had received one 14-day course of intravenous ganciclovir and all were free of other en
Changes in virus load markers during AIDS-associated opportunistic diseases in human immunodeficiency virus-infected persons.: J Infect Dis. 1996 Aug;174(2):401-3. Unique Identifier : AIDSLINE MED/96313021; Donovan RM; Bush CE; Markowitz NP; Baxa DM; Saravolatz LD; Department of Internal Medicine, Henry Ford Hospital, Detroit,; Michigan 48202, USA.; Human immunodeficiency virus (HIV) load markers are being used increasingly to monitor disease progression and evaluate antiretroviral therapy. This study examined plasma HIV RNA and p24 antigen levels before, during, and after 15 AIDS-associated opportunistic disease events in patients with AIDS (median CD4 cell coun
Human immunodeficiency virus type 1 kinetics in lymph nodes compared with plasma.: J Infect Dis. 1996 Aug;174(2):404-7. Unique Identifier : AIDSLINE MED/96313022; Lafeuillade A; Poggi C; Profizi N; Tamalet C; Costes O; Department of Infectious Diseases, General Hospital, Toulon,; France.; As lymphoid organs are the major reservoir of human immunodeficiency virus type 1 (HIV-1), the rates at which HIV-1 RNA decreases from the plasma and from a series of lymph node biopsies from 4 patients treated with a combination of zidovudine, didanosine, and lamivudine were measured. The concentrations of HIV-1 RNA
An immunohistochemical analysis of naturally occurring chancroid.: J Infect Dis. 1996 Aug;174(2):427-30. Unique Identifier : AIDSLINE MED/96313029; King R; Gough J; Ronald A; Nasio J; Ndinya-Achola JO; Plummer F; Wilkins JA; Department of Pathology, University of Manitoba, Winnipeg,; Canada.; Haemophilus ducreyi is a major cause of genital ulcer disease in many developing countries and is associated with augmented transmission of human immunodeficiency virus (HIV). However, the mechanisms through which H. ducreyi produces ulceration are poorly understood. The characteristics of the host response to H. ducr
Genital ulcers associated with human immunodeficiency virus-related immunosuppression [letter]: J Infect Dis. 1996 Aug;174(2):445-7. Unique Identifier : AIDSLINE MED/96313034; O'Farrell N
Human immunodeficiency virus (HIV) type 1-specific B cell response in seronegative subjects at risk for HIV exposure [letter]: J Infect Dis. 1996 Aug;174(2):447-8. Unique Identifier : AIDSLINE MED/96313035; Angarano G; Fiore JR; Di Stefano M; Monno L
Zidovudine resistance reverse transcriptase mutations during didanosine monotherapy [letter]: J Infect Dis. 1996 Aug;174(2):448-9. Unique Identifier : AIDSLINE MED/96313036; Shafer RW; Winters MA; Jellinger RM; Merigan TC
HIV, TB, and mental illness in a health clinic for the homeless.: J La State Med Soc. 1996 Jun;148(6):267-70. Unique Identifier : AIDSLINE MED/96293114; Townsend MH; Stock MS; Morse EV; Simon PM; LSU School of Medicine, Dept. of Psychiatry, New Orleans, USA.; The authors reviewed the medical records of both mentally ill and non-mentally ill patients in a clinic for the homeless population of New Orleans. The records of all psychiatric patients (n = 52) and a randomly selected comparison group (n = 236) of clinic patients without mental illness were chosen for review. Five
The inflammatory macrophage response to MCMV in mice with a retroviral immunodeficiency syndrome (MAIDS).: J Leukoc Biol. 1996 Jul;60(1):44-50. Unique Identifier : AIDSLINE MED/96295956; Allcock RJ; Peacock CD; Price P; Department of Microbiology, University of Western Australia,; Nedlands, Australia.; We have shown that normal C57BL/6J mice are moderately resistant to infection with murine cytomegalovirus (MCMV) and that this resistance is impaired by prior infection with LP-BM5 MuLV, which causes a disease (MAIDS) similar to early HIV-induced disease. This study investigates ma
Characterization of antisense RNA-mediated inhibition of SIV replication.: J Med Virol. 1996 Apr;48(4):321-5. Unique Identifier : AIDSLINE MED/96258547; Tung FY; Tung MH; Department of Infectious Diseases and Microbiology, Graduate; School of Public Health, University of Pittsburgh, PA 15261, USA.; Antisense RNA-mediated inhibition of HIV showed mixed success in previous experiments. In order to elucidate the parameters influencing the efficacy of an antisense RNA approach, retroviral vectors encoding 4.5 kb, 3.5 kb, or 2.5 kb antisense RNA of the gag-pol region of SIV (simian immunodeficiency virus) were constr
Hepatitis C plasma viral load is associated with HCV genotype but not with HIV coinfection.: J Med Virol. 1996 Apr;48(4):339-43. Unique Identifier : AIDSLINE MED/96258550; Berger A; von Depka Prondzinski M; Doerr HW; Rabenau H; Weber B; Institut fur Medizinische Virologie, Universitatskliniken; Frankfurt, a. M., Germany.; The influence of human immunodeficiency virus (HIV) coinfection and hepatitis C virus (HCV) genotype distribution on HCV viral load and alanine amino transferase (ALT) levels in chronically infected patients remains unclear. In the present study, serum samples from a group of haemophiliac patients were investigated re
Human herpesvirus 6 in human immunodeficiency virus-infected individuals: association with early histologic phases of lymphadenopathy syndrome but not with malignant lymphoproliferative disorders.: J Med Virol. 1996 Apr;48(4):344-53. Unique Identifier : AIDSLINE MED/96258551; Dolcetti R; Di Luca D; Carbone A; Mirandola P; De Vita S; Vaccher E; Sighinolfi L; Gloghini A; Tirelli U; Cassai E; Boiocchi M; Department of Experimental Oncology, INRCCS, Aviano (PN), Italy.; Preliminary evidence suggested that human herpesvirus-6 (HHV-6) may act as a cofactor in acquired immunodeficiency syndrome (AIDS) and may contribute to the pathogenesis of lymphoproliferative disorders occurring in individuals infected with the human immunodeficiency virus (HIV). To understand better the biological a
Viral safety of a new highly purified factor VIII (OCTATE).: J Med Virol. 1996 Apr;48(4):360-6. Unique Identifier : AIDSLINE MED/96258553; Biesert L; Lemon S; Goudeau A; Suhartono H; Wang L; Brede HD; Octapharma AG, Ziegelbrucke, Switzerland.; The inactivation of both transfusion-relevant and model viruses by modified pasteurisation (10 hours at 63 degrees C in solution) has been evaluated following the established guidelines of the EU CPMP Ad Hoc Working Party on Biotechnology/Pharmacy. This heat treatment was introduced into the manufacturing process of O
Antitumor germacranolides from Anvillea garcinii.: J Nat Prod. 1996 Apr;59(4):403-5. Unique Identifier : AIDSLINE MED/96209296; Abdel Sattar E; Galal AM; Mossa GS; Department of Pharmacognosy, College of Pharmacy, King Saud; University, Riyadh Saudi Arabia.; The aerial parts of Anvillea garcinii yielded two new germacranolides, 9 alpha-hydroxy-1 beta, 10 alpha-epoxyparthenolide (4) and parthenolid-9-one (5), in addition to the known 9 alpha-hydroxyparthenolide (1), 9 beta-hydroxyparthenolide (2), and 9 beta-hydroxy-1 beta, 10 alpha-epoxyparthenolide (3). The structures of
On the use of auxiliary data to estimate the survival function and its variance: an application to acquired immunodeficiency syndrome.: J Clin Epidemiol. 1996 Aug;49(8):899-905. Unique Identifier : AIDSLINE MED/96326372; Flandre P; INSERM, Villejuif, France.; Prospective studies have as their goal the estimation of the survival function when the time to the specified event may be censored due to loss to follow-up or to the termination of the study before the event of interest occurs. In such a study, information about an auxiliary event, correlated to the event of interest
Fear of AIDS, homophobia, and occupational risk for HIV. A staff development challenge.: J Nurs Staff Dev. 1995 Nov-Dec;11(6):313-9. Unique Identifier : AIDSLINE MED/96329512; Glad J; Tan WN; Erlen JA; Nursing is committed to providing quality care; however, nursing practice has been challenged by patients with AIDS. In this pilot study, the authors investigated the relation among nurses homophobia, fear AIDS, and occupational risk for contracting HIV. With their findings, they found that a positive attitude toward
Policy and position statement. Pediatric HIV disease. National Association of Pediatric Nurse Associates and Practitioners.: J Pediatr Health Care. 1996 Jan-Feb;10(1):44-5. Unique Identifier : AIDSLINE MED/96334440
Kaposi's sarcoma versus bacillary angiomatosis.: J Am Podiatr Med Assoc. 1996 Jun;86(6):260-2. Unique Identifier : AIDSLINE MED/96280311; Caldwell BD; Kushner D; Young B; Department of Podiatric Medicine, Ohio College of Podiatric; Medicine, Cleveland, USA.; Persons with acquired immune deficiency syndrome (AIDS) are subject to a host of pathologic entities secondary to a depressed immune system. Kaposi s sarcoma frequently presents in this immunocompromised population and, therefore, diagnosis seems clinically straightforward. However, because of the prevalence of a stri
Stand down for the homeless. Podiatric screening of a homeless population in Cleveland.: J Am Podiatr Med Assoc. 1996 Jun;86(6):275-9. Unique Identifier : AIDSLINE MED/96280314; Robbins JM; Roth LS; Villanueva MC; Department of Community Medicine, Ohio College of Podiatric; Medicine, Cleveland 44106, USA.; Health care for the homeless is a major public health concern. With the rise in antibiotic-resistant tuberculosis, the increase of human immunodeficiency virus (HIV) diseases, and other health risks, the medical community has begun to recognize the urgency of taking a proactive role in providing care for this populati
Transposable elements behavior following viral genomic stress in Drosophila melanogaster inbred line.: J Mol Evol. 1996 Jul;43(1):19-27. Unique Identifier : AIDSLINE MED/96304318; Jouan-Dufournel I; Cosset FL; Contamine D; Verdier G; Biemont C; Laboratoire de Biometrie, Genetique et Biologie des; Populations, UMR 5558, Universite Claude Bernard, Lyon 1, 69622; Villeurbanne Cedex, France.; To analyze the behavior of endogenous transposable elements under genomic stress, a Drosophila melanogaster inbred line was submitted to three kinds of viral perturbations. First, a retroviral plasmid containing the avian Rous Associated Virus type 2 (RAV-2) previously deleted for the viral envelope coding gene (env)
AIDS prevention in high-risk African American women: behavioral, psychological, and gender issues.: J Sex Marital Ther. 1996 Spring;22(1):9-21. Unique Identifier : AIDSLINE MED/96317937; Hetherington SE; Harris RM; Bausell RB; Kavanagh KH; Scott DE; University of Maryland at Baltimore School of Nursing 21230, USA.; A three-year longitudinal intervention study was implemented to reduce high-risk drug and sexual behaviors in methadone-dependent African American women. Participants were recruited from four inner-city methadone maintenance programs and randomly assigned either to an eight-week peer counseling and leadership training
Hepatitis, rash and eosinophilia following trichloroethylene exposure: a case report and speculation on mechanistic similarity to halothane induced hepatitis.: J Toxicol Clin Toxicol. 1996;34(4):461-6. Unique Identifier : AIDSLINE MED/96323007; Bond GR; Department of Emergency Medicine, University of Virginia,; Charlottesville 22908, USA.; CASE REPORT: A previously healthy 30-year-old male began work as a degreaser. The solvent used in the degreasing operation was trichloroethylene. Over the next month he experienced symptoms of weakness, dizziness, decreased appetite, nausea, abdominal pain, diarrhea, fever, chills, dry skin, red rash with bumps, peeli
[10th International Conference on AIDS in Yokohama]: Kango. 1994 Oct;46(12):164-72. Unique Identifier : AIDSLINE MED/96330040; Ishihara M
[Nursing care of patients with AIDS and education of nurses at Hospital Cochin in Paris: hospital organization]: Kango. 1994 Oct;46(12):173-83. Unique Identifier : AIDSLINE MED/96330041; Shimizu A
[Nursing care of patients with AIDS and education of nurses at Hospital Cochin in Paris: telling diagnosis, wearing gloves]: Kango. 1994 Nov;46(13):184-93. Unique Identifier : AIDSLINE MED/96330062; Shimizu A
[Human rights of AIDS patients and international collaboration. WHO Nursing Collaborative Center]: Kango. 1994 Nov;46(13):216-9. Unique Identifier : AIDSLINE MED/96330065
[Increased possibility for HIV-associated retinal microangiopathy syndrome in patients with concomitant hepatitis C infection]: Klin Monatsbl Augenheilkd. 1996 Mar;208(3):157-60. Unique Identifier : AIDSLINE MED/96237318; Thierfelder S; Linnert D; Universitats-Augenklinik Wurzburg.; BACKGROUND: The etiology of HIV-related retinal microangiopathy syndrome is yet unknown. Several authors postulate direct endothelial-cell infection, an immunocomplex vasculitis caused by HIV-related hypergammaglobulinemia or an increased serum concentration of endothelin as its origin. PATIENTS: 118 patients infected
Pentoxifylline for the treatment of HIV infection and its complications.: J Cardiovasc Pharmacol. 1995;25 Suppl 2:S139-42. Unique Identifier : AIDSLINE MED/96234442; Dezube BJ; Lederman MM; Department of Medicine, Beth Israel Hospital, Harvard Medical; School, Boston, Massachusetts 02215, USA.; The increased levels of tumor necrosis factor-alpha (TNF-alpha) seen in patients with acquired immune deficiency syndrome (AIDS) may contribute to the AIDS-related wasting syndrome. TNF also induces expression of human immunodeficiency virus (HIV) through activation of the transcription factor NF-kappa B, which binds
Impairment of polymorphonuclear neutrophil function in HIV-infected patients.: J Cardiovasc Pharmacol. 1995;25 Suppl 2:S66-70. Unique Identifier : AIDSLINE MED/96234427; Elbim C; Prevot MH; Bouscarat F; Franzini E; Chollet-Martin S; Hakim J; Gougerot-Pocidalo MA; INSERM U294, Paris, France.; Impaired polymorphonuclear neutrophil (PMN) function may contribute to the onset of certain bacterial and fungal infections and to tissue damage in human immunodeficiency virus (HIV)-infected patients. Published data on PMN function in HIV infection are controversial, possibly because most studies have involved PMNs i
Production of proinflammatory cytokines and cytokines involved in the TH1/TH2 balance is modulated by pentoxifylline.: J Cardiovasc Pharmacol. 1995;25 Suppl 2:S80-4. Unique Identifier : AIDSLINE MED/96234430; Bienvenu J; Doche C; Gutowski MC; Lenoble M; Lepape A; Perdrix JP; Laboratoire d'Immunologie, Centre Hospitalier Lyon-Sud, Pierre; Benite, France.; The modulation of cytokine release induced by pentoxifylline (PTX) has recently been demonstrated not to be restricted solely to tumor necrosis factor (TNF)-alpha. This prompted us to study the influence of PTX on a larger spectrum of cytokines with proinflammatory actions [TNF-alpha, interleukin-6, (IL)-6, IL-1 beta,
Microsporidian sinusitis in patients with the acquired immunodeficiency syndrome.: Laryngoscope. 1996 Aug;106(8):966-71. Unique Identifier : AIDSLINE MED/96320334; Rossi RM; Wanke C; Federman M; Harvard Medical School, Boston, MA USA.; Sinusitis in patients with human immunodeficiency virus (HIV) infection usually arises from the same organisms that are infective in the nonimmunosuppressed population. The authors of this article report that optimal antimicrobial treatment and functional endoscopic sinus surgery failed to eradicate sinonasal disease
Safety awareness for the otolaryngologist caring for the HIV-positive patient.: Laryngoscope. 1996 Aug;106(8):982-6. Unique Identifier : AIDSLINE MED/96320337; Kantu S; Lee D; Nash M; Lucente FE; Department of Otolaryngology, University Hospital of Brooklyn,; New York, USA.; The alarming increase in human immunodeficiency virus (HIV) infection, expected to reach 40 million cases worldwide by the year 2000, has enormous impact on the otolaryngologist, since up to 70% of HIV-positive patients present with head and neck symptoms. Parenteral and nonparenteral acquisition of HIV has been docum
Sulfadiazine-associated nephrotoxicity in patients with the acquired immunodeficiency syndrome.: Medicine (Baltimore). 1996 Jul;75(4):185-94. Unique Identifier : AIDSLINE MED/96320354; Becker K; Jablonowski H; Haussinger D; Department of Gastroenterology and Infectious Diseases, Heinrich; Heine University Medical Center, Dusseldorf, Germany.; We performed a computerized search on sulfadiazine-associated nephrotoxicity reported in human immunodefiency virus (HIV)-infected patients in the international literature. Including an original case report, we summarized 35 acquired immunodefiency syndrome (AIDS) patients from 1987 to 1995 in an analysis comparing th
Mandatory HIV testing of patients and professionals: bringing ethics into practice.: Med Educ. 1995 Sep;29(5):360-3. Unique Identifier : AIDSLINE MED/96286890; Berglund CA; School of Community Medicine, University of New South Wales,; Australia.; A contemporary health dilemma, that of mandatory HIV testing of patients and professionals, is used as a focus for an ethics class. Background material which is given to students is described and referenced. The interjection of ethical theory is described. The exercise has provided an effective focus for medical and h
2',3'-Didehydro-3'-deoxythymidine: regulation of its metabolic activation by modulators of thymidine-5'-triphosphate biosynthesis.: Mol Pharmacol. 1996 Jul;50(1):160-5. Unique Identifier : AIDSLINE MED/96295589; Ahluwalia GS; Gao WY; Mitsuya H; Johns DG; Laboratory of Medicinal Chemistry, National Cancer Institute,; National Institutes of Health, Bethesda, Maryland 20892-4255,; USA.; The anti-human immunodeficiency virus (anti-HIV) agent 2 ,3 -didehydro-3 -deoxythymidine (D4T), like other 2 ,3 -dideoxynucleosides, requires conversion to its 5 -triphosphate to exert its pharmacological effect. Although D4T-triphosphate is unusually potent as an inhibitor of HIV-1 reverse transcriptase, the phosphor
Ligands of the antiestrogen-binding site are able to inhibit virion production of human immunodeficiency virus 1-infected lymphocytes.: Mol Pharmacol. 1996 Jul;50(1):75-9. Unique Identifier : AIDSLINE MED/96295579; Mesange F; Delarue F; Puel J; Bayard F; Faye JC; Laboratoire d'Endocrinoldgie et Communication Cellulaire, INSERM; U397, Institut Louis Bugnard, CHU Rangueil, Toulouse, France.; Since the discovery of human immunodeficiency retrovirus, the drug arsenal against retrovirus has rapidly increased. Concomitantly, new challenges in the therapy of acquired immune deficiency syndrome have arisen, including drug toxicities, drug resistance, and the development of various cancers as effective therapies
Potent inhibition of human immunodeficiency virus and herpes simplex virus type 1 by 9-(2-phosphonylmethoxyethyl)adenine in primary macrophages is determined by drug metabolism, nucleotide pools, and cytokines.: Mol Pharmacol. 1996 Aug;50(2):359-66. Unique Identifier : AIDSLINE MED/96319786; Perno CF; Balestra E; Aquaro S; Panti S; Cenci A; Lazzarino G; Tavazzi B; Di Pierro D; Balzarini J; Calio R; Department of Experimental Medicine and Biochemical Sciences,; University of Rome Tor Vergata, Italy. perno@tovvx1.ccd.utovrm.it; The efficacy of 9-(2-phosphonylmethoxyethyl)adenine (PMEA) against the replication of human immunodeficiency virus (HIV) and herpes simplex virus type 1 (HSV-1) and its cellular metabolism were investigated in human primary macrophages from seronegative donors. PMEA potently inhibited the replication of both HIV and H
Highly favorable antiviral activity and resistance profile of the novel thiocarboxanilide pentenyloxy ether derivatives UC-781 and UC-82 as inhibitors of human immunodeficiency virus type 1 replication.: Mol Pharmacol. 1996 Aug;50(2):394-401. Unique Identifier : AIDSLINE MED/96319790; Balzarini J; Pelemans H; Aquaro S; Perno CF; Witvrouw M; Schols D; De Clercq E; Karlsson A; Rega Institute for Medical Research, Katholieke Universiteit; Leuven, Belgium. jan.balzarini@rega.kuleuven.ac.be; The novel human immunodeficiency virus type 1-specific thiocarboxanilide derivatives that contain either a substituted furanyl (UC-781) or thienyl (UC-82) ring linked to the thiocarboxy group and a pentenyloxyether chain linked to the 4-chlorophenyl ring in meta position show highly favorable antiviral properties. Com
'Beware of hype,' AIDS conference told [news]: Nature. 1996 Jul 11;382(6587):101. Unique Identifier : AIDSLINE MED/96317575; Macilwain C
Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice.: Nature. 1996 Jul 11;382(6587):174-7. Unique Identifier : AIDSLINE MED/96317591; Kaplan MH; Sun YL; Hoey T; Grusby MJ; Department of Cancer Biology, Harvard School of Public Health,; Boston, Massachusetts 02115, USA.; Interactions between cytokine and receptor lead to the activation of multiple signalling molecules, including the family of signal transducer and activator of transcription (STAT) proteins. STAT4 is one member of this family, and is activated only in response to the cytokine interleukin (IL)-12 (refs 5, 6). By gene ta
Unpublished findings not intended for reference [letter]: Mil Med. 1996 Jun;161(6):A4-5. Unique Identifier : AIDSLINE MED/96267924; Temoshok LR
[Visceral leishmaniasis in patients with HIV infection. Our experience]: Minerva Med. 1996 Jun;87(6):317-9. Unique Identifier : AIDSLINE MED/96314389; Terra L; Pellicano S; Allo M; Divisione Malattie Infettive, Ospedale S. Giovanni di Dio, USL n.; 5, Crotone.; The authors describe a case of visceral leishmaniasis in an intravenous drug abuser, HIV seropositive patient. Visceral leishmaniasis was the first opportunist infection and diagnosis was based on smear from bone marrow. A treatment with N-methylglucamine and allopurinol was successful. The authors stress to take into
The effects of an AIDS diagnosis on undergraduate nursing students' care of dying patients.: Nurse Educ. 1995 Nov-Dec;20(6):15-21. Unique Identifier : AIDSLINE MED/96335530; Bormann JE; Brent SB; Mood DW; Nurse educators frequently deal with nursing students discomfort in learning to care for dying patients. However, teaching students how to care for dying patients with acquired immune deficiency syndrome (AIDS) presents unique and interesting challenges. The authors describe the influence an AIDS diagnosis has on stu
Constitutively activated JNK is associated with HTLV-1 mediated tumorigenesis.: Oncogene. 1996 Jul 4;13(1):135-42. Unique Identifier : AIDSLINE MED/96292235; Xu X; Heidenreich O; Kitajima I; McGuire K; Li Q; Su B; Nerenberg M; Department of Molecular and Experimental Medicine, The Scripps; Research Institute, La Jolla, California 92307, USA.; Human T cell leukemia virus type I (HTLV-1) is the etiologic agent of adult T-cell leukemia (ATL) and HTLV-1 associated myelopathy, also called tropical spastic paraparesis (HAM/TSP). Both clinical and in vitro evidence have demonstrated that the virus or its transactivator Tax, are transforming. However, transformati
Tuberculosis and multi-drug resistant tuberculosis in children.: Pediatr Nurs. 1995 Nov-Dec;21(6):566-72. Unique Identifier : AIDSLINE MED/96334600; Peloquin CA; Berning SE; Infection and disease caused by Mycobacterium tuberculosis remain a hugh global problem, and are not well controlled in several areas within the United States . Co-infection with the human immunodeficiency virus (HIV) and immigration from areas with high rates of tuberculosis contribute
The influence of stress management training in HIV disease.: Nurs Res. 1996 Jul-Aug;45(4):246-53. Unique Identifier : AIDSLINE MED/96314397; McCain NL; Zeller JM; Cella DF; Urbanski PA; Novak RM; Department of Adult Health Nursing, School of Nursing, Virginia; Commonwealth University, Richmond, USA.; A pretest-posttest design (with a 6-week wait-list control and a 6-month comparison group) was used to compare the effectiveness of a 6-week stress management training program with standard outpatient care for 45 men with HIV disease. Outcomes included stress levels, coping patterns, quality of life, psychological dis
HIV/AIDS predictions proved wrong [news]: Nurs Times. 1996 Feb 14-20;92(7):9. Unique Identifier : AIDSLINE MED/96329261; Cassidy J
Evaluation of shared care for people with HIV [news]: Nurs Times. 1996 Feb 28-Mar 5;92(9):12. Unique Identifier : AIDSLINE MED/96334566; Smith S; Robinson J; Hollyer J
Alopecia associated with zidovudine therapy.: Pharmacotherapy. 1996 Jan-Feb;16(1):79-81. Unique Identifier : AIDSLINE MED/96286322; Geletko SM; Segarra M; Mikolich DJ; Department of Pharmacy Practice, University of Rhode Island; College of Pharmacy, Providence, 02908, USA.; Alopecia has been described in patients infected with the human immunodeficiency virus (HIV). Zidovudine reportedly influences hair growth in these patients, causing regrowth or thickening. A 33-year-old HIV-infected man developed alopecia areata after beginning zidovudine therapy. The alopecia reversed after the drug
Infectious myositis. A tropical disease steals out of its zone.: Postgrad Med. 1996 Aug;100(2):193-4, 199-200. Unique Identifier : AIDSLINE MED/96323051; O'Neill DS; Baquis G; Moral L; Department of Internal Medicine, Baystate Medical Center,; Springfield, MA 01199, USA.; Infectious myositis is an acute infection of skeletal muscle that is increasing in prevalence with the increased incidence of HIV disease. Typical presentation is asymmetric swelling of an isolated muscle, with exquisite pain and fever. Results of laboratory studies are usually nonspecific, but magnetic resonance imag
Urticaria. The diagnostic challenge of hives.: Postgrad Med. 1996 Aug;100(2):77-8, 81-4. Unique Identifier : AIDSLINE MED/96323044; Sveum RJ; Department of Allergy, Park Nicollet Clinic, Minneapolis, USA.; Hives pose a diagnostic challenge to physicians. With an acute episode, a careful look for possible triggers and relief of symptoms with H1 antihistamines are usually sufficient. For both urticaria and angioedema, the most helpful diagnostic tool may be a carefully taken medical history, including a family history. Wh
Human immunodeficiency virus type 1 and 2 Tat proteins specifically interact with RNA polymerase II.: Proc Natl Acad Sci U S A. 1996 Mar 5;93(5):2089-94. Unique Identifier : AIDSLINE MED/96312544; Mavankal G; Ignatius Ou SH; Oliver H; Sigman D; Gaynor RB; Division of Molecular Virology, University of Texas Southwestern; Medical Center, Dallas 75235-8594, USA.; The Tat-responsive region (TAR) element is a critical RNA regulatory element in the human immunodeficiency virus (HIV) long terminal repeat, which is required for activation of gene expression by the transactivator protein Tat. Recently, we demonstrated by gel-retardation analysis that RNA polymerase II binds to TAR R
Peptides from conserved regions of paramyxovirus fusion (F) proteins are potent inhibitors of viral fusion.: Proc Natl Acad Sci U S A. 1996 Mar 5;93(5):2186-91. Unique Identifier : AIDSLINE MED/96312562; Lambert DM; Barney S; Lambert AL; Guthrie K; Medinas R; Davis DE; Bucy T; Erickson J; Merutka G; Petteway SR Jr; Trimeris, Inc., Research Triangle Park, NC 27709, USA.; The synthetic peptides DP-107 and DP-178 (T-20), derived from separate domains within the human immunodeficiency virus type 1 (HIV-1) transmembrane (TM) protein, gp4l, are stable and potent inhibitors of HIV-1 infection and fusion. Using a computer searching strategy (computerized antiviral searching technology, C.A.S
Attitudes to drug users according to age of staff.: Prof Nurse. 1996 Mar;11(6):401-2, 404. Unique Identifier : AIDSLINE MED/96327538; Carroll J; The attitudes of professionals working with intravenous drug users, and their perceptions of service delivery, are likely to be affected by age. Younger professionals tend to be more positive in their attitudes towards intravenous drug users. Older professionals tend to be less concerned about the risks from HIV infec
[Rotavirus studied in the feces of 10 patients with the acquired immunodeficiency syndrome (AIDS)]: Rev Soc Bras Med Trop. 1996 May-Jun;29(3):283-4. Unique Identifier : AIDSLINE MED/96244796; Machado AA; Owa MA; de Freitas-Silva G; Figueiredo F de C; Martinez R; Departamento de Clinica Medica, Faculdade de Medicina de; Ribeirao Preto, Universidade de Sao Paulo.
[Cytomegalovirus retinitis in patients with AIDS (editorial)]: Rev Clin Esp. 1996 Apr;196(4):205-7. Unique Identifier : AIDSLINE MED/96254479; Verdejo Ortes J
[Intravitreal ganciclovir in cytomegalovirus retinitis in AIDS]: Rev Clin Esp. 1996 Apr;196(4):208-12. Unique Identifier : AIDSLINE MED/96254480; Olea JL; Salvat M; Mateos JM; Vila J; Villalonga C; Riera M; Servicio de Oftalmologia, Hospital Son Dureta, Palma de; Mallorca.; A retrospective study was made of 26 patients with AIDS who initially presented with retinitis as the only clinical manifestation of cytomegalovirus infection (39 eyes). Sixty-five induction or re-induction therapeutic courses were administered with intravitreal ganciclovir. The ef
[Usefulness of bone marrow examination in patients with advanced HIV infection]: Rev Clin Esp. 1996 Apr;196(4):213-6. Unique Identifier : AIDSLINE MED/96254481; Rodriguez JN; Dieguez JC; Moreno MV; Aguayo DM; Vega MD; Conde J; Prados D; Servicio de Hematologia, Hospital Juan Ramon Jimenez, Huelva.; A bone marrow investigation is a common examination in HIV infected patients for the study of cytopenia, febrile syndromes of unknown origin and extension of neoplastic disorders. A study was made of bone marrow specimens from 35 patients with advanced HIV infection (stage IC or C, CDC, Atlanta) for morphologic and cu
[Cellular immune response in tuberculosis: analysis of T-lymphocytes and their subsets, B-lymphocytes and natural cytotoxic cells in different tuberculosis states and body fluids]: Rev Clin Esp. 1996 Apr;196(4):223-7. Unique Identifier : AIDSLINE MED/96254483; Montes Santiago J; Gambon Deza F; Pacheco Carracedo M; Cerda Mota T; Servicio de Medicina Interna, Hospital de Meixoeiro, Vigo.; BACKGROUND. The immune response to Mycobacterium tuberculosis is primarily mediated by T lymphocytes. In this study an investigation was made of T lymphocytes and their subsets, B lymphocytes and natural cytotoxic cells (Natural Killer, NK) in blood and organic fluids in different tuberculosis conditions. METHODS. Pat
[Treatment of neutropenia in HIV infection with hematopoietic growth factors]: Rev Clin Esp. 1996 Apr;196(4):248-54. Unique Identifier : AIDSLINE MED/96254488; Moreno Garcia M; Fernandez Gonzalez F; Servicio de Medicina Interna, Hospital Penitenciario, Madrid.
[Surgical abdomen in a patient with human immunodeficiency virus infection (clinical conference)]: Rev Clin Esp. 1996 Apr;196(4):264-9. Unique Identifier : AIDSLINE MED/96254495
[Hematopoietic growth factors]: Rev Med Liege. 1996 Jan;51(1):102-6. Unique Identifier : AIDSLINE MED/96308108; Fillet G; Departement de Medecine, Service d'Hematologie, Universite de; Liege.
[Disseminated infection with Mycobacterium celatum]: Schweiz Med Wochenschr. 1996 Jun 15;126(24):1062-5. Unique Identifier : AIDSLINE MED/96271226; Emler S; Praplan P; Rohner P; Auckenthaler R; Hirschel B; Division des maladies infectieuses, Hopitaux universitaires de; Geneve.; A 29-year-old patient with AIDS was hospitalized with weight loss, fever and cough. Mycobacterial cultures from sputum, blood and bronchoalveolar lavage became positive after 3 weeks incubation. When using a DNA probe for identification of Mycobacterium tuberculosis complex, a weakly positive signal was obtained. Tub
[Role of hepatotropic viruses in liver pathology in Southwestern Cameroon]: Schweiz Med Wochenschr Suppl. 1996;79:36S-43S. Unique Identifier : AIDSLINE MED/96251556; Skalsky JA; Joller-Jemelka HI; Bianchi L; Knoblauch M; Presbyterian Medical Institutions Manyemen, SWP, Cameroon.; Between 1990 and 1992 (2 years), 102 patients with clinical liver pathology underwent standardized clinical, pathological, sonographic and serologic investigations (HAV, HBV, HCV, HDV autoantibodies and tumor markers). During the same period seroepidemiological studies with the same parameters as above were performed
HIV's Achilles' heel. Drugs and education are starting to slow the AIDS virus [news]: Sci Am. 1996 Sep;275(3):16, 18. Unique Identifier : AIDSLINE MED/96327163; Beardsley T
New chip off the old block. Can DNA microprobes do for genetics what microprocessors did for computing? [news]: Sci Am. 1996 Sep;275(3):42, 44. Unique Identifier : AIDSLINE MED/96349303; Gibbs WW
Reports bolster viral cause of KS [news]: Science. 1996 Aug 2;273(5275):573. Unique Identifier : AIDSLINE MED/96345541; Cohen J
Fetal immune response [letter]: Science. 1996 Aug 9;273(5276):722-3. Unique Identifier : AIDSLINE MED/96349293; Sarfati M; Delespesse G
Genome sequence of a human tumorigenic poxvirus: prediction of specific host response-evasion genes.: Science. 1996 Aug 9;273(5276):813-6. Unique Identifier : AIDSLINE GENBANK/U60315; Senkevich TG; Bugert JJ; Sisler JR; Koonin EV; Darai G; Moss B; Laboratory of Viral Diseases, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Bethesda, MD; 20892-0455, USA.; Molluscum contagiosum virus (MCV) commonly causes asymptomatic cutaneous neoplasms in children and sexually active adults as well as persistent opportunistic acquired immunodeficiency syndrome (AIDS)-associated disease. Sequencing the 190-kilobase pair genome of MCV has now revealed that the virus potentially encodes
Infection with hepatitis GB virus among Japanese hemophiliacs (letter).: Transfusion. 1996 Jul;36(7):669. Unique Identifier : AIDSLINE MED/96323067; Nishiyama Y; Nakashima H; Hino K; Mori K; Ishikawa M; Okamoto H
[Anus cancer]: Ugeskr Laeger. 1996 Jul 8;158(28):4073-6. Unique Identifier : AIDSLINE MED/96292602; Keldsen N; Laurberg S; Onkologisk afdeling D, Arhus Kommmunehospital.; The pathology, etiology and epidemiology of anal cancer (CA) and the treatment and prognostic factors are reviewed. CA is a rare disease. However, the incidence is rising and is now 0.7 per 100,000 women and 0.4 per 100,000 men in Denma
Serologic evidence for bovine immunodeficiency virus infection in France.: Vet Microbiol. 1996 Jan;48(1-2):165-73. Unique Identifier : AIDSLINE MED/96241245; Polack B; Schwartz I; Berthelemy M; Belloc C; Manet G; Vuillaume A; Baron T; Gonda MA; Levy D; Unite de Recherche Associee d'Immuno-Pathologie Cellulaire et; Moleculaire, Ecole Nationale Veterinaire d'Alfort, France.; We report herein on the first serologic detection of antibodies to bovine immunodeficiency virus (BIV) in France . Serum samples from dairy and beef cattle from southwestern and western France (Landes and Vendee) were tested using a western blot assay with a recombinant 53 kDa gag p
Overview: practical insights from comparative immunology and pathogenesis of AIDS, hepatitis B, and measles for developing an HIV vaccine.: Vaccine. 1995 Dec;13(18):1733-40. Unique Identifier : AIDSLINE MED/96264827; Hilleman MR; Merck Institute for Therapeutic Research, Merck Research; Laboratories, West Point, PA 19486, USA.; Combined effects of viral mutation, beneficial and adverse host immune responses, and alterations in immune function strongly fashion the pathogenesis and outcome of HIV infection. Understanding HIV can be aided by understanding hepatitis B and measles. Clinical remission and exacerbation in persistent hepatitis B vir
Immunization with a soluble recombinant HIV protein entrapped in biodegradable microparticles induces HIV-specific CD8+ cytotoxic T lymphocytes and CD4+ Th1 cells.: Vaccine. 1995 Dec;13(18):1741-9. Unique Identifier : AIDSLINE MED/96264828; Moore A; McGuirk P; Adams S; Jones WC; McGee JP; O'Hagan DT; Mills KH; Biology Department, St. Patrick's College, Maynooth, Co. Kildare,; Ireland.; One of the major obstacles to the development of successful recombinant vaccines against human immunodeficiency virus (HIV) and other intracellular pathogens is the identification of a safe and effective vaccine delivery system for the induction of cell mediated immunity with soluble protein antigens. In this study it
[AIDS prevention in homosexuals in Switzerland: adaptation to risks according to type of partner]: Soz Praventivmed. 1996;41(1):1-10. Unique Identifier : AIDSLINE MED/96317878; Moreau-Gruet F; Dubois-Arber F; Institut universitaire de medecine sociale et preventive,; Lausanne.; OBJECTIVE: To evaluate the effectiveness of AIDS prevention and modes of adaptation to risk among gay men. Swiss results are presented from an international study conducted in 8 European countries. METHOD: A self-administered questionnaire was published in gay magazines and distributed by gay organizations and clubs.
[The effect of streptococcal group A polysaccharide on PHA-induced T-cell proliferation]: Zh Mikrobiol Epidemiol Immunobiol. 1996 Mar-Apr;(2):71-3. Unique Identifier : AIDSLINE MED/96254369; Bazanova EA; Gnezditskaia EV; Nesterenko VG; Popova LK; Sanina VIu; Ignatenko IN; The influence of group A streptococcal polysaccharide (A-PS) on the proliferation and functional activity of subpopulations CD4+ and CD8+ of human peripheral blood lymphocytes has been studied. As revealed in this study, A-PS, though having no mitogenic activity of its own, is capable of influencing the process of pro
AILD-like dysplasia transformed in AILD-type T cell lymphoma in an HTLV-1 carrier: usefulness of interferon-alpha.: Acta Haematol. 1996;96(2):92-8. Unique Identifier : AIDSLINE MED/96328248; Kozuru M; Hashimoto M; Takahira H; Uike N; Ohoshima K; Takeshita M; Kikuchi M; Clinical Research Institute, National Kyushu Cancer Center,; Fukuoka, Japan.; A 61-year-old Japanese woman who was an HTLV-1 carrier had angioimmunoblastic lymphadenopathy with dysproteinemia (AILD)-like dysplasia that transformed into AILD-type lymphoma after 3 years. Complete remission was achieved with interferon-alpha (IFN-alpha) treatment following a previous combination of anticancer drug
Pyomyositis.: Am Fam Physician. 1996 Aug;54(2):565-9. Unique Identifier : AIDSLINE MED/96320130; Dunkerley GR; Older J; Onwochei B; Pazienza J; St. Clare's Hospital, Schenectady, New York, USA.; In the past, most cases of pyomyositis occurred among persons living in tropical climates, with the most common pathogen being Staphylococcus aureus. Increased numbers of cases have been reported more recently in North America, particularly in immunocompromised persons, such as those infected with the human immunodefi
Antiretroviral drug treatment for HIV/AIDS.: Am Fam Physician. 1996 Aug;54(2):574-80, 587-8. Unique Identifier : AIDSLINE MED/96320131; Goldschmidt RH; Moy A; San Francisco General Hospital, California, USA.; As new antiretroviral drugs for the treatment of human immunodeficiency virus (HIV) infection and new tests to measure HIV infection have become available, primary care clinicians now have more management options than ever before. Viral load measurements are becoming more accepted as a means of assessing HIV disease a
CD20 (pan-B cell antigen) expression on bone marrow-derived T cells.: Am J Clin Pathol. 1996 Jul;106(1):78-81. Unique Identifier : AIDSLINE MED/96291101; Algino KM; Thomason RW; King DE; Montiel MM; Craig FE; Department of Pathology, University of Texas Health Science; Center, San Antonio 78284, USA.; Antibodies directed against CD20 (L26, Leu 16, and B1) are frequently used to determine the presence of B lymphocytes. However, recent publications describe the unexpected presence of CD20-positive T cells in the peripheral blood of normal subjects and occasional T-cell neoplasms that express CD20. To determine the pr
Acquired factor V inhibitor in a patient with acquired human immunodeficiency syndrome [letter]: Am J Hematol. 1996 Aug;52(4):332-3. Unique Identifier : AIDSLINE MED/96319653; Brickner LA; Scannell KA; Sahud MA
Fas antigen expression and its relationship with apoptosis in human hepatocellular carcinoma and noncancerous tissues.: Am J Pathol. 1996 Aug;149(2):429-37. Unique Identifier : AIDSLINE MED/96312846; Higaki K; Yano H; Kojiro M; First Department of Pathology, Kurume University School of; Medicine, Japan.; Apoptosis, a programmed cell death, can be observed in the tissues of viral or autoimmune hepatitis and of hepatocellular carcinoma. Fas antigen (Fas) was proposed as a protein that triggers apoptosis. To elucidate the relationship between Fas expression and its location in hepatocellular carcinoma cells, we histochem
T cell subsets in normal human epidermis.: Am J Pathol. 1996 Aug;149(2):665-74. Unique Identifier : AIDSLINE MED/96312868; Spetz AL; Strominger J; Groh-Spies V; Division of Tumor Virology, Dana Farber Cancer Institute, Boston,; Massachusetts, USA.; Freshly isolated human lymphocytes from normal epidermis were characterized with respect to distribution of subsets. The major T cell receptor-alpha beta + compartment was enriched for CD4+, for CD8 alpha alpha +, and for CD4-CD8-T lymphocytes compared with peripheral blood lymphocytes. Furthermore, the majority of ep
Preventing opportunistic infections in human immunodeficiency virus-infected persons: implications for the developing world.: Am J Trop Med Hyg. 1996 Jul;55(1):1-11. Unique Identifier : AIDSLINE MED/96320181; Kaplan JE; Hu DJ; Holmes KK; Jaffe HW; Masur H; De Cock KM; Division of AIDS, STD, and TB Laboratory Research, National; Center for Infectious Diseases, Centers for Disease Control and; Prevention, Atlanta, Georgia, USA.; More than 18 million persons in the world are estimated to have been infected with human immunodeficiency virus (HIV), the cause of the acquired immunodeficiency syndrome (AIDS). As immunodeficiency progresses, these persons become susceptible to a wide variety of opportunistic infections (OIs) The spectrum of OIs var
Comparability of treatment groups and risk factors for parasitemia at the first antenatal clinic visit in a study of malaria treatment and prevention in pregnancy in rural Malawi.: Am J Trop Med Hyg. 1996;55(1 Suppl):17-23. Unique Identifier : AIDSLINE MED/96320168; Steketee RW; Wirima JJ; Slutsker L; Breman JG; Heymann DL; Division of Parasitic Diseases, National Center for Infectious; Diseases, Centers for Disease Control and Prevention, Atlanta,; Georgia, USA.; The problems of Plasmodium falciparum infection in pregnant women have been described in numerous sub-Saharan African countries, but the frequency of parasitemia at the first antenatal visit and risk factors for infection have not been fully investigated. During a prospective antimalarial treatment and prophylaxis tri
Malaria parasite infection during pregnancy and at delivery in mother, placenta, and newborn: efficacy of chloroquine and mefloquine in rural Malawi.: Am J Trop Med Hyg. 1996;55(1 Suppl):24-32. Unique Identifier : AIDSLINE MED/96320169; Steketee RW; Wirima JJ; Slutsker L; Roberts JM; Khoromana CO; Heymann DL; Breman JG; Division of Parasitic Diseases, National Center for Infectious; Diseases, Centers for Disease Control and Prevention, Atlanta,; Georgia, USA.; Despite international recommendations to use malaria treatment and prevention in pregnant women in malaria-endemic areas, few studies have evaluated the efficacy of available antimalarial regimens. This issue is of particular concern in the face of spreading chloroquine (CQ)-resistance of Plasmodium falciparum in mala
The effect of malaria and malaria prevention in pregnancy on offspring birthweight, prematurity, and intrauterine growth retardation in rural Malawi.: Am J Trop Med Hyg. 1996;55(1 Suppl):33-41. Unique Identifier : AIDSLINE MED/96320170; Steketee RW; Wirima JJ; Hightower AW; Slutsker L; Heymann DL; Breman JG; Division of Parasitic Diseases, National Center for Infectious; Diseases, Centers for Disease Control and Prevention, Atlanta,; Georgia, USA.; While there is broad evidence for the adverse effects of Plasmodium falciparum infection in pregnancy, and the World Health Organization recommends preventive strategies, there is markedly reduced efficacy in sub-Saharan Africa of the most widely available, affordable and used antimala
Impairment of a pregnant woman's acquired ability to limit Plasmodium falciparum by infection with human immunodeficiency virus type-1.: Am J Trop Med Hyg. 1996;55(1 Suppl):42-9. Unique Identifier : AIDSLINE MED/96320171; Steketee RW; Wirima JJ; Bloland PB; Chilima B; Mermin JH; Chitsulo L; Breman JG; Division of Parasitic Diseases, National Center for Infectious; Diseases, Centers for Disease Control and Prevention, Atlanta,; Georgia, USA.; In Africa, the human immunodeficiency virus (HIV) is the most serious emerging infection and Plasmodium falciparum malaria is one of the most prevalent infectious diseases. Both infections have serious consequences in pregnant women, their fetuses, and infants. We examined the association between HIV and P. falciparum
Malaria treatment and prevention in pregnancy: indications for use and adverse events associated with use of chloroquine or mefloquine.: Am J Trop Med Hyg. 1996;55(1 Suppl):50-6. Unique Identifier : AIDSLINE MED/96320172; Steketee RW; Wirima JJ; Slutsker L; Khoromana CO; Heymann DL; Breman JG; Division of Parasitic Diseases, National Center for Infectious; Diseases, Centers for Disease Control and Prevention, Atlanta,; Georgia, USA.; In sub-Saharan Africa, women frequently report a variety of symptoms during pregnancy, some of which indicate possible illness. Given the adverse impact of malaria in pregnancy, these events may be important for at least two reasons: it may be possible to use reported fever illness as a determinant of which women need
Prospective assessment of mortality among a cohort of pregnant women in rural Malawi.: Am J Trop Med Hyg. 1996;55(1 Suppl):66-70. Unique Identifier : AIDSLINE MED/96320175; McDermott JM; Slutsker L; Steketee RW; Wirima JJ; Breman JG; Heymann DL; Division of Parasitic Diseases, National Center for Infectious; Diseases, Centers for Disease Control and Prevention, Atlanta,; Georgia, USA.; Maternal mortality has recently received attention as a neglected public health problem in many developing countries where mortality rates are estimated to be 8-200 times those in developed countries. Most maternal mortality estimates in sub-Saharan Africa have used retrospective methods because of the lack of large p
Objectives and methodology in a study of malaria treatment and prevention in pregnancy in rural Malawi: The Mangochi Malaria Research Project.: Am J Trop Med Hyg. 1996;55(1 Suppl):8-16. Unique Identifier : AIDSLINE MED/96320167; Steketee RW; Wirima JJ; Slutsker WL; Khoromana CO; Breman JG; Heymann DL; Division of Parasitic Diseases, National Center for Infectious; Diseases, Centers for Disease Control and Prevention, Atlanta,; Georgia, USA.; Malaria infection due to Plasmodium falciparum has been widely recognized as associated with important adverse consequences in pregnant women, particularly in areas of high transmission. Although strategies using antimalarial drugs for prevention had been recommended, even by the late 1980s, few studies had been carri
Rates and risk factors for mortality during the first two years of life in rural Malawi.: Am J Trop Med Hyg. 1996;55(1 Suppl):82-6. Unique Identifier : AIDSLINE MED/96320178; Bloland P; Slutsker L; Steketee RW; Wirima JJ; Heymann DL; Breman JG; Division of Parasitic Diseases, National Center for Infectious; Diseases, Centers for Disease Control and Prevention, Atlanta,; Georgia, USA.; Developing nations in sub-Saharan Africa experience childhood mortality rates that are much higher than any other region of the world. In a rural Malawian community we investigated risk factors for deaths occurring during the neonatal (birth-28 days), postneonatal (29-365 days), infant (birth-365 days), and second-yea
Developing effective strategies for malaria prevention programs for pregnant African women.: Am J Trop Med Hyg. 1996;55(1 Suppl):95-100. Unique Identifier : AIDSLINE MED/96320180; Steketee RW; Wirima JJ; Campbell CC; Division of HIV/AIDS, National Center for Prevention Services,; Centers for Disease Control and Prevention, Atlanta, Georgia,; USA.; The control of malaria in pregnant African women, one of several child survival strategies applied through antenatal care, has been particularly challenging. Prevention and control recommendations for typical areas of high Plasmodium falciparum transmission have promoted the use of antimalarial chemoprophylaxis to pre
Nurses combat HIV/AIDS in adolescent community.: Am Nurse. 1995 Nov-Dec;27(8):16. Unique Identifier : AIDSLINE MED/96322625; Campbell K
Home care nursing: bringing the hospital home.: Am Nurse. 1995 Nov-Dec;27(8):17. Unique Identifier : AIDSLINE MED/96322626; Lemkin P
Immunohistochemical characterisation of immunological changes at the tumour site after chemo-immunotherapy with doxorubicin, interleukin-2 and interferon-gamma.: Anticancer Res. 1996 May-Jun;16(3A):1145-54. Unique Identifier : AIDSLINE MED/96273137; Lumsden AJ; Codde JP; Van der Meide PH; Gray BN; Centre for Applied Cancer Studies, Royal Perth Hospital,; Australia.; Chemo-immunotherapy for the treatment of cancer, whilst promising from a preclinical and clinical perspective, remains limited by a lack of clear understanding of the in vivo antitumour mechanisms of this multi modality strategy. There is now strong evidence that systemic immunological parameters do not correlate with
Human T lymphotropic virus type I in arthropathy and autoimmune disorders.: Arthritis Rheum. 1996 Aug;39(8):1410-8. Unique Identifier : AIDSLINE MED/96320246; Nishioka K; Sumida T; Hasunuma T; Institute of Medical Science, St. Marianna University School of; Medicine, Kawasaki, Japan.; The progressive nature of the disease and the persistent inflammation affecting various organs are common features of idiopathic autoimmune disorders of unknown etiology. Therefore, the HTLV-I-associated disorders described in the present review are outstandingly important models for our understanding of the pathologi
The relationship between rheumatoid arthritis and the acquired immunodeficiency syndrome: comment on the article by Ornstein et al [letter]: Arthritis Rheum. 1996 Aug;39(8):1437-9. Unique Identifier : AIDSLINE MED/96320255; Adebajo AO; Hazleman BL
Organ transplantation and the inevitable debate as to what constitutes a basic health care benefit.: Terasaki, Paul; Cecka, J.M., eds. Clinical Transplants 1993. Los Angeles, CA: UCLA Tissue Typing Laboratory, 1994 :359-391. Unique Identifier : AIDSLINE KIE/50102; Evans RW
When doctors and patients decide to test the far limits of treatment. [News].: New York Times. 1995 Dec 19;:C3. Unique Identifier : AIDSLINE KIE/50255; Altman LK
Surgery gives man new best friends. [News].: New York Times. 1995 Dec 17;:E3. Unique Identifier : AIDSLINE KIE/50256; Stryker J
Cross-species transplants raise concerns about human safety. [News].: New York Times. 1996 Jan 9;:11, 17. Unique Identifier : AIDSLINE KIE/50257; Altman LK
Transplant: urgent step or step off the edge? [News].: New York Times. 1996 Jan 9;:16. Unique Identifier : AIDSLINE KIE/50258; Kolata G
When victims need to know: sometimes it's O.K. to test the accused for HIV.: New York Times. 1996 Jan 18;:A23. Unique Identifier : AIDSLINE KIE/50353; Bayer R
Legislation would allow judges to order H.I.V. tests for suspects. [News].: New York Times. 1996 Jan 12;:B1, B2. Unique Identifier : AIDSLINE KIE/50391; Levy CJ
A comparative study of tuberculin skin test reactivity between asymptomatic HIV-1 seropositive subjects and healthy volunteers.: Asian Pac J Allergy Immunol. 1995 Dec;13(2):139-44. Unique Identifier : AIDSLINE MED/96259691; Suwanagool S; Chuenarom V; Pechthanon L; Sonjai A; Leelarasamee A; Pathrakom C; Department of Preventive and Social Medicine, Faculty of Medicine; Siriraj Hospital, Mahidol University, Bangkok, Thailand.; During November 1993-October 1994 tuberculin skin test reactivity (PPD-Thai Red Cross: 0.1 ml of 10 IU) was determined among 399 asymptomatic HIV-1 positive subjects and 405 healthy volunteers, 10% (40/399) had PPD-TRC induration 0-2 mm compared with 4.2% (17/405) (p = 0.001) and 43.4% (173/399) had induration > or =
Bacillary angiomatosis: microbiology, histopathology, clinical presentation, diagnosis and management.: Bol Asoc Med P R. 1995 Jul-Sep;87(7-9):140-6. Unique Identifier : AIDSLINE MED/96292823; Ramirez Ramirez CR; Saavedra S; Ramirez Ronda C; Infectious Diseases Program, University of Puerto Rico School of; Medicine, San Juan 00927-5800.; Bacillary angiomatosis is known to be caused by a rickettsial organism; Rochalimaea henselae. This causative agent has been compared with different microorganisms and clinical conditions that appear in similar settings buy have been clearly differentiated from them; e.i. Cat-scratch disease (Afipia felis), Bartonella
Simian virus 40 transformation alters the actin cytoskeleton, expression of matrix metalloproteinases and inhibitors of metalloproteinases, and invasive behavior of normal and ataxia-telangiectasia human skin fibroblasts.: Biochem Cell Biol. 1995 Jul-Aug;73(7-8):373-89. Unique Identifier : AIDSLINE MED/96273739; Hansell EJ; Frisch SM; Tremble P; Murnane JP; Werb Z; Laboratory of Radiobiology and Environmental Health, University; of California, San Francisco 94143-0750, USA.; Alterations in the actin cytoskeleton of normal cells result in changes in cell shape and adhesiveness and induce expression of matrix-degrading matrix metalloproteinases. We examined the effect of simian virus 40 transformation of normal and ataxia-telangiectasia human skin fibroblasts, a process that produces actin
Number of activated T-helper cells and NK cells in peripheral blood is decreased in severe Crohn's disease.: APMIS. 1996 May;104(5):355-61. Unique Identifier : AIDSLINE MED/96302319; Kontiainen S; Scheinin T; Halme L; Department of Pathology, University of Helsinki, Finland.; Monoclonal antibodies and flow cytometry were used to analyse the proportions of T-cell subsets and NK cells in blood of patients (n = 45) with Crohn s disease. In patients with severe activity disease decreased numbers of activated (CD25+CD4+) T-helper cells and NK (CD16+CD56+) cells were found, while in patients wit
Patterns of HIV/AIDS in Zimbabwe: implications for health education.: AIDS Educ Prev. 1996 Feb;8(1):1-10. Unique Identifier : AIDSLINE MED/96282022; Munodawafa D; Gwede C; Department of Physical and Health Education, University of Akron,; Ohio 44325-5103, USA.; Current patterns of HIV/AIDS in Zimbabwe are examined using national surveillance data reflecting four main variables: age, gender, marital status, and residence. The data show that the distribution of cases by age and gender is consistent with the literature on the rest of sub-S
AIDS education for college students: review and proposal for a research-based curriculum.: AIDS Educ Prev. 1996 Feb;8(1):11-25. Unique Identifier : AIDSLINE MED/96282023; Mulvihill CK; Biology Department, Community College of Allegheny County,; Pittsburgh, PA 15212, USA.; The history of AIDS education for college students in the U.S. is reviewed. Wide agreement concerning the goals and overall content of the AIDS-education curriculum is found. However, the context and location of AIDS education within the curriculum vary considerably. Increased knowledge about AIDS is a frequent outcom
What African-American women know, do, and feel about AIDS: a function of age and education.: AIDS Educ Prev. 1996 Feb;8(1):26-36. Unique Identifier : AIDSLINE MED/96282024; Dancy B; University of Illinois at Chicago, College of Nursing 60612, USA.; Because African-American women tend to be studied as a homogeneous group, little data exist that report differences in what they know, feel, and do about AIDS. The purpose of this study was to compare African-American women across two age groups and four educational groups to discern if differences exist. African-Amer
Mental health-related calls to the CDC National AIDS Hotline.: AIDS Educ Prev. 1996 Feb;8(1):37-43. Unique Identifier : AIDSLINE MED/96282025; Safran MA; Waller RR; Centers for Disease Control and Prevention, Atlanta, GA 30333,; USA.; The CDC National AIDS Hotline provides confidential HIV-related information and referrals to anonymous callers, twenty-four hours a day. As part of a continuing quality improvement assessment of caller informational needs, 302 randomly selected anonymous overnight calls to the Hotline were evaluated for mental health-
Childhood sexual abuse linked with adult substance use, victimization, and AIDS-risk.: AIDS Educ Prev. 1996 Feb;8(1):44-57. Unique Identifier : AIDSLINE MED/96282026; Johnsen LW; Harlow LL; Department of Psychology, University of Rhode Island, Kingston; 02881-0808, USA.; College women who report childhood sexual abuse were compared with women who do not report abuse on a number of variables concerned with problems in living. Multivariate Analysis of Variance revealed that, compared with nonabused women, sexually abused women reported significantly more negative attitudes about sexuali
Compliance with AZT treatment regimen of HIV-seropositive injection drug users: a neglected issue.: AIDS Educ Prev. 1996 Feb;8(1):58-71. Unique Identifier : AIDSLINE MED/96282027; Freeman RC; Rodriguez GM; French JF; Division of Alcoholism, Drug Abuse, and Addiction Services, New; Jersey State Department of Health, USA.; Although treatment with zidovudine ( AZT ) is now recommended for asymptomatic and symptomatic HIV-infected persons with CD4+ cell counts of 0.20 to 0.50 x 10(9)/L and under, data gathered from a small convenience sample of current and former injection
Correlates of acceptance of HIV testing and post-test counseling in the obstetrical setting.: AIDS Educ Prev. 1996 Feb;8(1):72-85. Unique Identifier : AIDSLINE MED/96282028; Sorin MD; Tesoriero JM; LaChance-McCullough ML; Wadsworth Center for Laboratories & Research, Axelrod Institute; for Public Health, Albany, NY 12201, USA.; Recent results of AZT testing among pregnant women by NIH indicate that early diagnosis and medical intervention can reduce vertical transmission of HIV. Debates have been rekindled concerning whether testing should remain voluntary or be made mandato
My guardian angel: a learning exercise for adolescent AIDS education.: AIDS Educ Prev. 1996 Feb;8(1):86-91. Unique Identifier : AIDSLINE MED/96282029; Geiger BF; Tierney MA; Department of Human Studies, University of Alabama at Birmingham,; School of Education 35294-1250, USA.; This article describes the methods to conduct a simple role-play exercise. The purpose of the exercise is to practice skills to prevent HIV infection and AIDS, including peer communication about personal health decisions among high school and college students. With guidance from the instructor, each student individual
Animal donors.: Nurs Stand. 1996 Mar 6;10(24):16. Unique Identifier : AIDSLINE MED/96339869; Andrews J
Is sex safer? If you've heard one slogan, you've heard them all [letter]: Nurs Stand. 1996 Mar 6;10(24):21. Unique Identifier : AIDSLINE MED/96339871; Hawkins WS
Take a balanced view [news]: Nurs Stand. 1996 Mar 13;10(25):12. Unique Identifier : AIDSLINE MED/96339881; Williams K
Undiagnosed hypercoagulable state: a case study.: J Vasc Nurs. 1995 Dec;13(4):117-27. Unique Identifier : AIDSLINE MED/96332127; McKeown ES; Vascular nursing presents constant challenges. The natural history of vascular disease coupled with the complexity of the patient population provides an environment for constant learning. Providing care to these unique individuals demands a thorough knowledge of vascular anatomy and physiology, diagnostic intervention
Differential expression of CD3 and CD7 in T-cell malignancies: a quantitative study by flow cytometry.: Br J Haematol. 1996 Jun 2;93(4):921-7. Unique Identifier : AIDSLINE MED/96290544; Ginaldi L; Matutes E; Farahat N; De Martinis M; Morilla R; Catovsky D; Academic Department of Haematology and Cytogenetics, Royal; Marsden Hospital, London.; Most T-cell antigens are expressed on normal and neoplastic T lymphocytes and for this reason it is not easy to distinguish between the immunophenotype of normal and malignant T cells. We have addressed this problem by comparing the levels of expression of CD3 and CD7 on T lymphocytes from 18 healthy donors with those
Diagnostic assays in cytomegalovirus retinitis: detection of herpesvirus by simultaneous application of the polymerase chain reaction and local antibody analysis on ocular fluid [see comments]: Br J Ophthalmol. 1996 Mar;80(3):235-40. Unique Identifier : AIDSLINE MED/96246710; Doornenbal P; Seerp Baarsma G; Quint WG; Kijlstra A; Rothbarth PH; Niesters HG; The Eye Hospital, Rotterdam, The Netherlands.; AIM: To determine the value of the polymerase chain reaction (PCR) technique and the analysis of intraocularly produced antibodies by calculating a Goldmann-Witmer quotient (GWq) as diagnostic assays in the confirmation of a clinically diagnosed cytomegalovirus (
Ultrastructural features and prevalence of tubuloreticular structures in the ocular vasculature of patients with AIDS: a study of 23 cases.: Br J Ophthalmol. 1996 Mar;80(3):252-5. Unique Identifier : AIDSLINE MED/96246713; Maturi RK; Font RL; Department of Ophthalmology, Cullen Eye Institute, Baylor College; of Medicine, Houston, TX, USA.; BACKGROUND: Tubuloreticular structures (TRS) are subcellular inclusions that are most commonly found in endothelial cells and lymphocytes of patients with autoimmune or collagen vascular disorders. In AIDS, TRS have been described in various tissues throughout the body including the lung, kidney, liver, muscle, and sk
Chemical modification of recombinant HIV-1 capsid protein p24 leads to the release of a hidden epitope prior to changes of the overall folding of the protein.: Biochemistry. 1996 Jul 16;35(28):9097-105. Unique Identifier : AIDSLINE MED/96291251; Ehrhard B; Misselwitz R; Welfle K; Hausdorf G; Glaser RW; Schneider-Mergener J; Welfle H; Institut fur Medizinische Immunologie and Institut fur; Biochemie, Universitatsklinikum Charite, Humboldt-Universitat; zu Berlin, Germany.; It was found that the affinity of a monoclonal antibody directed against a recombinantly expressed HIV-1 capsid protein p24 (rp24) strongly increased after chemical modification of the Iysine residues of rp24 with different amounts of maleic anhydride. The extent and the sites of modification were analyzed by MALDI-TO
Structure/nuclease activity relationships of DNA cleavers based on cationic metalloporphyrin-oligonucleotide conjugates.: Biochemistry. 1996 Jul 16;35(28):9140-9. Unique Identifier : AIDSLINE MED/96291256; Mestre B; Jakobs A; Pratviel G; Meunier B; Laboratoire de Chimie de Coordination du CNRS, Toulouse, France.; The covalent attachment of a managanese-tris(methylpyridiniumyl)porphyrin entity to an antisense oligonucleotide allowed sequence-selective oxidative cleavage of DNA when the metalloporphyrin was activated by potassium monopersulfate (KHSO5). We prepared several structurally modified metallo-porphyrin-oligonucleotide
A drug resistance mutation in the inhibitor binding pocket of human immunodeficiency virus type 1 reverse transcriptase impairs DNA synthesis and RNA degradation.: Biochemistry. 1996 Jul 30;35(30):9737-45. Unique Identifier : AIDSLINE MED/96312887; Fan N; Rank KB; Slade DE; Poppe SM; Evans DB; Kopta LA; Olmsted RA; Thomas RC; Tarpley WG; Sharma SK; Upjohn Laboratories, Kalamazoo, Michigan 49001, USA.; Selection of the IIIB strain of human immunodeficiency virus type (HIV-1) resistant to the (alkylamino)piperidine-bis(heteroaryl)piperazine (AAP-BHAP) U-104489 results in substitution of a glycine to glutamate at residue 190 (G190E) of reverse transcriptase (RT). The AAP-BHAP resistant HIV-1 displays reduced in vitro
Human immunodeficiency virus type-1 (HIV-1) infection increases the sensitivity of macrophages and THP-1 cells to cytotoxicity by cationic liposomes.: Biochim Biophys Acta. 1996 Jul 24;1312(3):186-96. Unique Identifier : AIDSLINE MED/96313822; Konopka K; Pretzer E; Felgner PL; Duzgunes N; Department of Microbiology, University of the Pacific School of; Dentistry, San Francisco, CA 94115, USA.; Cationic liposomes may be valuable for the delivery of anti-sense oligonucleotides, ribozymes, and therapeutic genes into human immunodeficiency virus type 1 (HIV-1)-infected and uninfected cells. We evaluated the toxicity of three cationic liposomal preparations, Lipofectamine, Lipofectin, and 1, 2-dimyristyloxypropy
ICN calls for more protection against HIV/AIDS.: Nurs BC. 1996 Jan-Feb;28(1):10. Unique Identifier : AIDSLINE MED/96345434
Distribution of prolyl oligopeptidase in human peripheral tissues and body fluids.: Eur J Clin Chem Clin Biochem. 1996 Jan;34(1):17-22. Unique Identifier : AIDSLINE MED/96284121; Goossens F; De Meester I; Vanhoof G; Scharpe S; Laboratorium voor Medische Biochemie, Universiteit Antwerpen; (UIA), Wilrijk, Belgium.; Prolyl oligopeptidase (EC 3.4.21.26) activity was measured in human tissue homogenates and body fluids. The enzyme was ubiquitously present, revealing high activity in renal cortex, epithelial cells, fibroblasts, testis, lymphocytes and thrombocytes. The activity in the body fluids was low. Prolyl oligopeptidase activ
Cellular and molecular immunology of an important regulatory cytokine. New York 9-12, November 1995.: Eur Cytokine Netw. 1996 Jan-Mar;7(1):79-81. Unique Identifier : AIDSLINE MED/96258457; Chouaib S; Escudier B; Chehimi J; CJF 9411 INSERM, Institut Gustave Roussy, Villejuif, France.
Exposure of human CD34+ cells to human immunodeficiency virus type 1 does not influence their expansion and proliferation of hematopoietic progenitors in vitro.: Blood. 1996 Jul 1;88(1):130-7. Unique Identifier : AIDSLINE MED/96290417; Kaushal S; La Russa VF; Gartner S; Kessler S; Perfetto S; Yu Z; Ritchey DW; Xu J; Perera P; Kim J; Reid T; Mayers DL; St. Louis D; Mosca JD; Department of Hematology and Vascular Biology, Walter Reed Army; Institute of Research, Washington, DC; USA.; The susceptibility of highly purified human CD34+ cells to monocytotropic (Ba-L) and lymphotropic (A018-post) strains of human immunodeficiency virus-1 (HIV-1) was examined. Liquid cultures initiated with fresh immunomagnetically purified CD34+ cells using the K6.1 CD34 monoclonal antibody (MoAb) (K6.1/CD34+) were pos
Activation of naive and memory T cells by interleukin-15.: Blood. 1996 Jul 1;88(1):230-5. Unique Identifier : AIDSLINE MED/96290428; Kanegane H; Tosato G; Division of Hematologic Products, Food and Drug Administration,; Bethesda, MD 20852, USA.; Interleukin-15 (IL-15), a product of monocytes and other cells, has biological activities similar to those of IL-2 , including growth stimulation of activated T cells, induction of cytolytic effector cells, and B-cell costimulation for proliferation and lg production. W
Epstein-Barr virus latent membrane protein-1 oncogene deletions: correlations with malignancy in Epstein-Barr virus--associated lymphoproliferative disorders and malignant lymphomas.: Blood. 1996 Jul 1;88(1):242-51. Unique Identifier : AIDSLINE MED/96290430; Kingma DW; Weiss WB; Jaffe ES; Kumar S; Frekko K; Raffeld M; Division of Cancer Biology, Diagnosis and Centers, National; Cancer Institute, National Institutes of Health, Bethesda, MD; 20892-1500, USA.; LMP-1, an Epstein-Barr viral (EBV) latency protein, is considered a viral oncogene because of its ability to transform rodent fibroblasts in vivo and render them tumorigenic in nude mice. In human B cells, EBV LMP-1 induces DNA synthesis and abrogates apoptosis. LMP-1 is expressed in EBV-transformed lymphoblastoid cel
Favored use of immunoglobulin V(H)4 Genes in AIDS-associated B-cell lymphoma.: Blood. 1996 Jul 1;88(1):252-60. Unique Identifier : AIDSLINE MED/96290431; Bessudo A; Cherepakhin V; Johnson TA; Rassenti LZ; Feigal E; Kipps TJ; Department of Medicine, University of California at San Diego, La; Jolla, 92093-0663, USA.; We examined the lg heavy chain variable region genes (Ig V(H) genes) expressed in biopsy specimens of 10 patients with acquired immunodeficiency syndrome (AIDS)-associated lymphoma. Eight expressed Ig V(H) genes of the V(H)4 group, indicating a bias toward expression of Ig V(H) genes of this subgroup. Sequence analyse
Kaposi's sarcoma (KS)-associated herpesvirus-like DNA sequences in peripheral blood mononuclear cells: association with KS and persistence in patients receiving anti-herpesvirus drugs.: Blood. 1996 Jul 1;88(1):297-301. Unique Identifier : AIDSLINE MED/96290436; Humphrey RW; O'Brien TR; Newcomb FM; Nishihara H; Wyvill KM; Ramos GA; Saville MW; Goedert JJ; Straus SE; Yarchoan R; Medicine Branch National Cancer Institute, National Institutes of; Health, Bethesda, MD 20892-1906, USA.; Herpesvirus-like DNA sequences (KSHV/HHV-8) have recently been described in AIDS-associated Kaposi s sarcoma (KS) lesions. Many questions remain regarding the role of this virus in KS and the therapeutic implications of this finding. In the current study, KSHV/HHV-8 DNA was detected in peripheral blood mononuclear cel
Thiotepa cyclophosphamide followed by granulocyte colony-stimulating factor mobilized allogeneic peripheral blood cells in adults with advanced leukemia.: e Thiotepa/ADMINISTRATION & DOSAGE Tissue Donors Transplantation, Homologous Treatment Outcome CLINICAL TRIAL JOURNAL ARTICLE Blood. 1996 Jul 1;88(1):353-7. Unique Identifier : AIDSLINE MED/96290444; Bacigalupo A; Van Lint MT; Valbonesi M; Lercari G; Carlier P; Lamparelli T; Gualandi F; Occhini D; Bregante S; Valeriani A; Piaggio G; Pitto A; Benvenuto F; Figari O; De Stefano G; Caimo A; Sessarego M; Divisione Ematologia 2, Ospedale San Martino, Genova, Italy.
Interleukin-10 gene expression in adult T-cell leukemia.: Blood. 1996 Aug 1;88(3):1035-45. Unique Identifier : AIDSLINE MED/96309650; Mori N; Gill PS; Mougdil T; Murakami S; Eto S; Prager D; Department of Medicine, Cedars-Sinai Medical Center, UCLA School; of Medicine 90048, USA.; We studied the serum levels of interleukin-10 (IL-10), in patients with adult T-cell leukemia (ATL) caused by human T-cell leukemia virus type I (HTLV-I) infection. Elevated IL-10 levels were observed in 33 of 45 patients with ATL. Fresh leukemic cells from ATL patients as well as HTLV-I-infected T-cell lines MT-2, SL
Cystamine inhibits human immunodeficiency virus-1 replication in cord blood-derived mononuclear phagocytes and lymphocytes.: Blood. 1996 Aug 1;88(3):928-33. Unique Identifier : AIDSLINE MED/96309637; Ho WZ; Kaufman D; Song L; Cutillii JR; Douglas SD; Division of Immunology and Infectious Diseases, Children's; Hospital of Philadelphia 19104, USA.; The effects of cystamine on the human immunodeficiency virus (HIV-1) expression in cord blood monocytes-derived macrophages (CBMDM) and lymphocytes were investigated. Cystamine suppressed HIV-1 expression in CBMDM and lymphocytes in a concentration-dependent fashion as determined by HIV-1 reverse transcriptase (RT) ac
Tumor vaccination with macrophage colony-stimulating factor-producing Lewis lung carcinoma in mice.: Blood. 1996 Aug 1;88(3):955-61. Unique Identifier : AIDSLINE MED/96309640; Morita T; Ikeda K; Douzono M; Yamada M; Kimura F; Kawakami K; Sasaki K; Motoyoshi K; Takahara J; Irino S; Health Science Center, Kagawa University, Japan.; Expression of various cytokines by cytokine gene-transduced tumor cells has been shown to increase antitumor immunity of tumor-bearing hosts. In the present study, macrophage-colony stimulating factor (M-CSF) cDNA was retrovirally transfected into Lewis lung carcinoma cells (3LL) of C57BL/6 mouse origin, and the effec
[A survey on infection control practices, knowledge and attitudes toward AIDS/HIV among dental practitioners]: Nippon Koshu Eisei Zasshi. 1996 May;43(5):364-73. Unique Identifier : AIDSLINE MED/96300985; Aizawa F; Yonemitsu M; Aizawa Y; Hanada N; Akada H; Department of Oral Science, The National Institute of Health.; A survey was conducted in December 1993 by sending questionnaires to all 566 dentists of the Iwate Dental Association. The questionnaires consisted of 68 items including infection control practices, knowledge, and attitudes towards AIDS/HIV. The response rate was 51.1 percent (N = 289). The average age of dentists in
The child with HIV infection.: J Sch Nurs. 1995 Dec;11(4):29-38; quiz 39. Unique Identifier : AIDSLINE MED/96339584; Gross E
Infection control in GP surgeries: safe practices?: Br J Nurs. 1996 Mar 28-Apr 10;5(6):341-2, 344-8. Unique Identifier : AIDSLINE MED/96344800; Finn L; McCulloch J; Any increase in the use of invasive procedures carries with it an increased risk of cross-infection. The spread of the human immunodeficiency virus, together with increasing awareness of hepatitis B virus, cytomegalovirus and human papillomavirus have focused attention on the natur
Ask the midwife--on HIV/AIDS and nursing mothers.: Birth Gaz. 1995 Fall;11(4):40-1. Unique Identifier : AIDSLINE MED/96339465; Edmonds J
Midwifery, hiv and aids.: Birth Gaz. 1995 Winter;12(1):12-8. Unique Identifier : AIDSLINE MED/96339468; Edmunds J
Russia is on brink of AIDS epidemic [news]: BMJ. 1996 Aug 3;313(7052):252. Unique Identifier : AIDSLINE MED/96322667; Ingram M
Prospective study of the role of cardiac troponin T in patients admitted with unstable angina.: BMJ. 1996 Aug 3;313(7052):262-4. Unique Identifier : AIDSLINE MED/96322670; Stubbs P; Collinson P; Moseley D; Greenwood T; Noble M; Academic Unit of Cardiovascular Medicine, Charing Cross and; Westminster Medical School, Charing Cross Hospital, London.; OBJECTIVE--To examine the prognostic significance and role in risk stratification of the biochemical marker troponin T in patients admitted with unstable angina. DESIGN--Single centre, blinded, prospective study of patients admitted with chest pain. SETTING--Coronary care unit of a district general hospital. SUBJECTS-
Role of community pharmacies in relation to HIV prevention and drug misuse: findings from the 1995 national survey in England and Wales [see comments]: BMJ. 1996 Aug 3;313(7052):272-4. Unique Identifier : AIDSLINE MED/96322677; Sheridan J; Strang J; Barber N; Glanz A; National Addiction Centre, Institute of Psychiatry, London.; OBJECTIVES--To establish activity levels of community (high street) pharmacies in the provision of HIV prevention services to drug misusers and to compare these findings with the levels identified in 1988. DESIGN--Self completion questionnaire (four mailings) to a random 1 in 4 sample of all community pharmacies, stra
Rights and responsibilities in HIV prevention. Article was misleading [letter]: BMJ. 1996 Aug 3;313(7052):303. Unique Identifier : AIDSLINE MED/96322706; Bailey P
Rights and responsibilities in HIV prevention. AIDS might have been tackled differently if it had presented as a disease of women [letter]: BMJ. 1996 Aug 3;313(7052):303-4. Unique Identifier : AIDSLINE MED/96322707; Breimer LH
Rights and responsibilities in HIV prevention. HIV negative people should be responsible for protecting themselves [letter]: BMJ. 1996 Aug 3;313(7052):304. Unique Identifier : AIDSLINE MED/96322708; MacWilliam S
Immunomagnetic CD4+ and CD8+ cell depletion for patients at high risk for severe acute GVHD.: Bone Marrow Transplant. 1996 Mar;17(3):377-82. Unique Identifier : AIDSLINE MED/96243877; Jansen J; Hanks S; Akard LP; Thompson JM; Burns S; Chang Q; English D; Garrett P; Bone Marrow Transplantation Program Methodist Hospital of; Indiana, Indianapolis 46206-1367, USA.; Acute GVHD remains a major problem in allogeneic BMT, in particular when donors other than HLA-identical siblings are used. To determine the efficacy of an immunomagnetic method for depletion of CD4+ and CD8+ lymphocytes from the marrow graft, a series of 15 patients was studied. Thirteen patients had matched unrelate
New, emerging, and re-emerging infectious diseases.: Bull Pan Am Health Organ. 1996 Jun;30(2):176-81. Unique Identifier : AIDSLINE MED/96333975
Trends in age at the first medical evaluation of human immunodeficiency virus infection among infants born to infected mothers. New York City Pediatric Spectrum of HIV Disease Clinical Consortium.: Arch Pediatr Adolesc Med. 1996 Aug;150(8):787-9. Unique Identifier : AIDSLINE MED/96316813; Obiri GU; Thomas PA; Caldwell B; New York City Department of Health, Control and Prevention,; Atlanta, Ga, USA.; OBJECTIVE: To evaluate the trends in age at the first medical evaluation of human immunodeficiency virus (HIV) infection among infants enrolled in the Pediatric Spectrum of Disease study born to mothers infected with HIV. DESIGN: Retrospective study based on medical chart review. SETTING: Nine pediatric centers in New
Response of human immunodeficiency virus-exposed and -infected infants to Haemophilus influenzae type b conjugate vaccine.: Arch Pediatr Adolesc Med. 1996 Aug;150(8):838-41. Unique Identifier : AIDSLINE MED/96316822; Rutstein RM; Rudy BJ; Cnaan A; Division of General Pediatrics, Children's Hospital of; Philadelphia (Pa), USA.; OBJECTIVE: To evaluate the response of human immunodeficiency virus (HIV)-infected and -exposed infants to the primary series and booster dose of Haemophilus influenzae type b (Hib) conjugate vaccine. DESIGN: Retrospective study. PATIENTS AND SETTING: The HIV-exposed and -infected infants who were attending the Specia
Let's make health research a #1 priority.: Revolution. 1996 Spring;6(1):50. Unique Identifier : AIDSLINE MED/96345125; Beane L
Nurses and HIV. Beware the experts!: Revolution. 1996 Spring;6(1):55-8. Unique Identifier : AIDSLINE MED/96345128; Stearley H
Drug abuse, AIDS, and the coming crisis in long-term care.: J Nurs Manag. 1996 May;4(3):151-62. Unique Identifier : AIDSLINE MED/96345394; Montoya ID; Chenier EE; Richard AJ; As the 21st century approaches and the proportion of the US population over 65 years of age increases, it is expected that the demand for long-term care will expand dramatically. This expectation has been widely discussed. Less widely discussed is a potential for increase in the demand for long-term care resulting, no
[Development and evaluation of screening algorithms for sexually transmitted diseases in pregnant women at Libreville, Gabon]: Sante. 1996 Mar-Apr;6(2):115-21. Unique Identifier : AIDSLINE MED/96260131; Bourgeois A; Henzel D; Dibanga G; Minko NN; Peeters M; Coulaud JP; Fransen L; Delaporte E; IMEA/Inserm U13, CHU Bichat-C. Bernard, Paris, France; The struggle against sexually transmitted diseases (STD) constitutes a priority of public health in developing countries: STD cause complications, particularly in pregnant women, and facilitate the transmission of HIV. One of the strategies in the struggle against STD is the diagnosis and the early treatment of these
[AIDS and drug addiction (editorial)]: Sante. 1996 Mar-Apr;6(2):68. Unique Identifier : AIDSLINE MED/96260114; Gentilini M
[Methadone in France. The experience of the Monte Cristo center of the Laennec Hospital in Paris]: Sante. 1996 Mar-Apr;6(2):69. Unique Identifier : AIDSLINE MED/96260115; Lowenstein W; Service de Medecine interne I, Hopital Laennec, Paris, France.
[Strategy for risk reduction of HIV infection in drug addicts in South Vietnam]: Sante. 1996 Mar-Apr;6(2):70. Unique Identifier : AIDSLINE MED/96260116; Le TG; Comite du Sida de Ho Chi Minh-Ville, Viet-nam.
[HIV epidemiology among drug addicts in the city of Ho Chi Minh. Trends between 1992 and 1995]: Sante. 1996 Mar-Apr;6(2):70-1. Unique Identifier : AIDSLINE MED/96260117; Nguyen DT; Truong XL; Centre de Medecine preventive, Ho Chi Minh-Ville, Vie-nam.
[Clinical dermatologic and genital manifestations in drug addicts infected with HIV]: Sante. 1996 Mar-Apr;6(2):71. Unique Identifier : AIDSLINE MED/96260118; Nguyen VU; Van M; Nguyen TT; Nguyen TM; Centre de sevrage de la toxicomanie de Binh Trieu, Ho Chi; Minh-Ville, Viet-nam.
[Epidemiologic trends of HIV infection in South Vietnam]: Sante. 1996 Mar-Apr;6(2):72-3. Unique Identifier : AIDSLINE MED/96260119; Nguyen TT; Ha BK; Institut Pasteur, Ho Chi Minh-Ville, Vi t-nam.
[Clinical and epidemiologic aspects of HIV infection among drug addicts in Ho Chi Minh city]: Sante. 1996 Mar-Apr;6(2):73. Unique Identifier : AIDSLINE MED/96260120; Nguyen HC; Centre des maladies tropicales, Ho Chi Minh-Ville, Viet-nam.
[AIDS epidemiology and intravenous drug use in Europe]: Sante. 1996 Mar-Apr;6(2):74. Unique Identifier : AIDSLINE MED/96260121; Duneton P; Service de sante publique, Groupe hospitalier de la; Pitie-Salpetriere, Paris, France.
[Tuberculosis in patients infected with HIV in Ho Chi Minh city]: Sante. 1996 Mar-Apr;6(2):74. Unique Identifier : AIDSLINE MED/96260122; Pham DL; Centre de pneumologie de Pham Ngoc Thach, Ho Chi Minh-Ville,; Viet-nam.
[Somatic pathology in drug addicts infected with HIV]: Sante. 1996 Mar-Apr;6(2):75. Unique Identifier : AIDSLINE MED/96260123; Coulaud JP; Service de maladies infectieuses et tropicales, Paris, France.
[Reduction in crimes of drug addiction in North America]: Sante. 1996 Mar-Apr;6(2):75-6. Unique Identifier : AIDSLINE MED/96260124; Bruneau J; Hopital Saint-Luc, Centre de prise en charge de la toxicomanie,; Montreal, Quebec, Canada.
[AIDS and drug addiction in North America. Drug addiction epidemiology]: Sante. 1996 Mar-Apr;6(2):76-8. Unique Identifier : AIDSLINE MED/96260125; Hankins C; Centre Sida McGill 1616, boulevard Rene-Levesque Quest,; Montreal, Quebec, Canada.
Case report: Pneumocystis carinii pneumonia presenting as a solitary cavitating lung lesion in non-HIV immunosuppressed patients.: Br J Radiol. 1996 May;69(821):472-5. Unique Identifier : AIDSLINE MED/96334793; Uwyyed K; Bar-Ziv J; Kramer MR; Institute of Pulmonology, Hadassah University Hospital,; Jerusalem, Israel.; Pneumocystis carinii is one of the most common pulmonary opportunistic infections in immunodeficient patients. It has a classical chest radiographic appearance of bilateral interstitial infiltrates. Recently, cystic or cavitating lesions have been reported in HIV patients with Pneumocystis carinii pneumonia. We report
Castleman's disease in children: the experience of a children's hospital in Africa.: Pediatr Pathol Lab Med. 1995 Nov-Dec;15(6):857-68. Unique Identifier : AIDSLINE MED/96187391; Taylor KL; Kaschula RO; Department of Pathology, Red Cross Children's Hospital,; Rondebosch, South Africa.; As the incidence of childhood Castleman s disease (CD) is reported to be rare in Western communities, the recent occurrence of three cases in non-HIV infected prepubertal children stimulated a 10-year (1983-1993) retrospective investigation into the conditions at a children s hospital that serves a predominantly devel
Adrenal gland leiomyoma in a child with acquired immunodeficiency syndrome.: Pediatr Pathol Lab Med. 1995 Nov-Dec;15(6):923-9. Unique Identifier : AIDSLINE MED/96187397; Jimenez-Heffernan JA; Hardisson D; Palacios J; Garcia-Viera M; Gamallo C; Nistal M; Department of Pathology, Hospital La Paz, Madrid, Spain.; An adrenal gland leiomyoma was incidentally found at autopsy in a 2-year-old boy with acquired immunodeficiency syndrome (AIDS). Smooth muscle neoplasms have been described in pediatric AIDS and affect mainly the tracheobronchopulmonary, gastrointestinal, and hepatobiliary systems. An association between Epstein-Barr
Premalignant conditions of the small intestine.: Semin Gastrointest Dis. 1996 Apr;7(2):88-93. Unique Identifier : AIDSLINE MED/96271230; Ryan JC; Gastroenterology Section, University of California San Francisco,; USA.; Cancer of the small intestine is rare compared with other sites in the gastrointestinal tract. Of the four major primary small-bowel tumors (adenocarcinomas, lymphomas, carcinoid, and leiomyosarcomas), adenocarcinomas and lymphomas are associated with diseases that seem to increase the risk of developing these maligna
[Problems and perspectives of wider use of saliva for diagnostic purposes]: Bratisl Lek Listy. 1996 May;97(5):304-7. Unique Identifier : AIDSLINE MED/96303547; Dubayova K; Kusnir J; Ustav lekarskej chemie a biochemie, Lekarskej fakulty,; Univerzity P.J. Safarika, Kosiciach, Slovakia.; dubayova@kosice.upjs.sk; Saliva of individual salivary glands differs in appearance, density and particularly in the chemical composition. Generally, the composition of saliva is affected by the composition of blood plasma, salivary flow rate, hormonal activity, drug administration, smoking and other physiological and pathophysiological state
Key developments in HIV maternity care.: Mod Midwife. 1995 Dec;5(12):8-9. Unique Identifier : AIDSLINE MED/96333536; Chester T; Cassidy L; Lewis P
Herpesviridae-associated persistent mucocutaneous ulcers in acquired immunodeficiency syndrome. A clinicopathologic study.: Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1996 Apr;81(4):433-41. Unique Identifier : AIDSLINE MED/96288806; Flaitz CM; Nichols CM; Hicks MJ; University of Texas-Houston Health Science Center, Bering Service; Foundation Dental Clinic, Baylor College of Medicine, Houston,; USA.; Persistent mucocutaneous ulcers in AIDS represent a variety of disease entities. The purpose of this study was to characterize clinicopathologic features of persistent oral ulcers associated with cytomegalovirus and herpes simplex virus in AIDS. Forty-seven persons infected with HI
Presence of human herpesvirus-like DNA sequence in oral Kaposi's sarcoma. A preliminary PCR study.: Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1996 Apr;81(4):442-4. Unique Identifier : AIDSLINE MED/96288807; Jin YT; Tsai ST; Yan JJ; Chen FF; Lee WY; Li WY; Chiang H; Su IJ; Department of Pathology, National Cheng Kung University Medical; Center, Tainan, Taiwan.; DNA sequences closely related to herpesvirus-like sequences have been found in AIDS-associated Kaposi s sarcoma. Subsequent studies indicate that these DNA sequences may be consistently found in AIDS Kaposi s sarcoma and non-AIDS Kaposi s sarcoma from different geographic regions. Oral Kaposi s sarcoma is rare and the
Immunopathogenesis of fish allergy: identification of fish-allergic adults by skin test and radioallergosorbent test.: Ann Allergy Asthma Immunol. 1996 Jul;77(1):48-54. Unique Identifier : AIDSLINE MED/96302211; Helbling A; McCants ML; Musmand JJ; Schwartz HJ; Lehrer SB; Inselspital Hopital de L'ile, Universitat von Berne,; Switzerland.; BACKGROUND: As the consumption of fish increases in the United States , the importance of allergic reactions to fish has become clear. Since most previous studies on fish allergy have focused on children reacting mainly to codfish, there is a need to investigate allergic reactions to ot
HIV/AIDS: an imperative for a new paradigm for caring.: N Hc Perspect Community. 1995 Nov-Dec;16(6):310-5. Unique Identifier : AIDSLINE MED/96339627; Walker MB; Frank L
Lymphocyte subpopulation reference ranges for monitoring human immunodeficiency virus-infected Chinese adults.: Clin Diagn Lab Immunol. 1996 May;3(3):326-30. Unique Identifier : AIDSLINE MED/96336091; Kam KM; Leung WL; Kwok MY; Hung MY; Lee SS; Mak WP; Department of Health, Sai Ying Pun Polyclinic, Hong Kong.; Two hundred eight healthy human immunodeficiency virus (HIV) type 1- and HIV type 2-seronegative Chinese adults (78 males and 130 females; mean age, 32 years; age range, 18 to 71 years) were analyzed for lymphocyte subsets by a standardized and quality-controlled flow cytometric immunophenotyping technique. While the
Antibody responses to defined epitopes in the Epstein-Barr virus BZLF1-encoded transactivator protein among human immunodeficiency virus-infected patients.: Clin Diagn Lab Immunol. 1996 May;3(3):363-4. Unique Identifier : AIDSLINE MED/96336099; Tedeschi R; Dillner J; De Paoli P; Microbiology-Immunology and Virology Division, Istituto Nazionale; di Ricovero e Cura a Carattere Scientifico, Aviano, Italy.; The Epstein-Barr virus BZLF1-encoded replication activator (ZEBRA) is a key mediator of reactivation from latency to the viral productive cycle. In the present study, the serum antibody responses against three defined ZEBRA epitopes (designated ZEBRA-1, -19, and -22) were determined for 50 human immunodeficiency virus
Distributive justice and HIV disease in intensive care.: Crit Care Nurs Q. 1996 May;19(1):55-64. Unique Identifier : AIDSLINE MED/96339498; Lamke C; Human immunodeficiency virus (HIV) infection presents ethical dilemmas for health care professionals involved in critical care settings. Although critical care may prolong life for those with life-threatening illness or surgeries, the long-term outcome is still poor for those infected with HIV. Health care professiona
Primary non-Hodgkin lymphomas of the CNS-proliferation, oncoproteins and Epstein-Barr-virus.: Gen Diagn Pathol. 1996 Mar;141(3-4):235-42. Unique Identifier : AIDSLINE MED/96262451; Bergmann M; Blasius S; Bankfalvi A; Mellin W; Institute of Clinical Neuropathology, Zentralkrankenhaus,; Bremen-Ost, Germany.; Primary cerebral lymphomas (PCL s) are rare tumors which, however, occur with increasing frequency. The present study investigated 55 PCL s of B-cell type, 36 in immunocompetent and 19 in AIDS-patients and 6 cases of intravascular lymphomatosis. In immunocompetent patients, proliferative indices as evaluated by PC10 a
Perforation of the small intestine in a patient with disseminated Pneumocystis carinii infection in AIDS.: Gen Diagn Pathol. 1996 Mar;141(3-4):255-60. Unique Identifier : AIDSLINE MED/96262454; Bierhoff E; Tran A; Pakos E; Rockstroh J; Pfeifer U; Department of Pathology, Rheinische; Friedrich-Wilhelms-University, Bonn, Germany.; Perforation of the small intestine due to a segmental transmural Pneumocystis carinii infiltrate of the whole circumference was found in a surgical resection specimen as the cause of an acute abdomen in a 48-year-old heterosexual male patient suffering from acquired immunodeficiency syndrome. On autopsy, a disseminate
Plasma HIV viremia and viral load in lymph nodes [letter]: Nat Med. 1996 Aug;2(8):832-3. Unique Identifier : AIDSLINE MED/96313084; Dianzani F; Antonelli G; Riva E; Uccini S; Visco G
Vaccination against tuberculosis by DNA injection.: Nat Med. 1996 Aug;2(8):888-92. Unique Identifier : AIDSLINE MED/96313103; Tascon RE; Colston MJ; Ragno S; Stavropoulos E; Gregory D; Lowrie DB; Division of Mycobacterial Research, National Institute for; Medical Research, The Ridgeway, Mill Hill, London, UK.; There are 3 million deaths per annum worldwide due to tuberculosis, and AIDS is compounding the problem. A better vaccine than the live mycobacterium currently in use, bacillus Calmette-Guerin (BCG), is needed. When mice were injected with plasmid DNA encoding a single mycobacterial antigen (65-kDa heat shock protein,
Suppressive vaccination with DNA encoding a variable region gene of the T-cell receptor prevents autoimmune encephalomyelitis and activates Th2 immunity [see comments]: Nat Med. 1996 Aug;2(8):899-905. Unique Identifier : AIDSLINE MED/96313105; Waisman A; Ruiz PJ; Hirschberg DL; Gelman A; Oksenberg JR; Brocke S; Mor F; Cohen IR; Steinman L; Department of Immunology, Weizmann Institute of Science, Rehovot,; Israel.; A variable region gene of the T-cell receptor, V beta 8.2, is rearranged, and its product is expressed on pathogenic T cells that induce experimental autoimmune encephalomyelitis (EAE) in H-2u mice after immunization with myelin basic protein (MBP). Vaccination of these mice with naked DNA encoding V beta 8.2 protecte
Large clonal expansions of CD8+ T cells in acute infectious mononucleosis.: Nat Med. 1996 Aug;2(8):906-11. Unique Identifier : AIDSLINE MED/96313106; Callan MF; Steven N; Krausa P; Wilson JD; Moss PA; Gillespie GM; Bell JI; Rickinson AB; McMichael AJ; Molecular Immunology Group, John Radcliffe Hospital, Headington,; Oxford, UK.; Primary infection with Epstein-Barr virus often results in the clinical syndrome of acute infectious mononucleosis (glandular fever). This illness is characterized by a striking lymphocytosis, the nature of which has been controversial. We show that large monoclonal or oligoclonal populations of CD8+ T cells account f
The seroepidemiology of human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus): distribution of infection in KS risk groups and evidence for sexual transmission [see comments]: Nat Med. 1996 Aug;2(8):918-24. Unique Identifier : AIDSLINE MED/96313108; Kedes DH; Operskalski E; Busch M; Kohn R; Flood J; Ganem D; Howard Hughes Medical Institute, University of California, San; Francisco 94143-0414, USA.; Striking differences in Kaposi s sarcoma (KS) risk for AIDS patients who acquire HIV via homosexual activity and those whose HIV infections derive from blood product exposure suggest the presence of a sexually transmitted agent other than HIV in the development of KS. Using an immunofluorescence assay, we examined ser
KSHV antibodies among Americans, Italians and Ugandans with and without Kaposi's sarcoma [see comments]: Nat Med. 1996 Aug;2(8):925-8. Unique Identifier : AIDSLINE MED/96313109; Gao SJ; Kingsley L; Li M; Zheng W; Parravicini C; Ziegler J; Newton R; Rinaldo CR; Saah A; Phair J; Detels R; Chang Y; Moore PS; Division of Epidemiology, School of Public Health, College of; Physicians and Surgeons, Columbia University, New York, New York; 10032, USA.; A major controversy regarding Kaposi s sarcoma-associated herpesvirus (KSHV or HHV8) is whether or not it is a ubiquitous infection of humans. Immunoassays based on KSHV- and Epstein-Barr virus (EBV)-coinfected cell lines show that most US AIDS-KS patients have specific antibodies to KSHV-related antigens. We have dev
Cytomegalovirus colitis in an immunocompetent old woman successfully treated with ganciclovir: a case report.: Chung Hua I Hsueh Tsa Chih (Taipei). 1996 Apr;57(4):289-92. Unique Identifier : AIDSLINE MED/96334008; Tsai HL; Huang CK; Cho G; Chen GH; Yang MD; Department of Internal Medicine, Taichung Veterans General; Hospital, Taiwan, R.O.C.; Cytomegalovirus ( CMV ) diseases occur almost exclusively in the immunocompromised hosts. Persons most commonly affected are patients with acquired immunodeficiency syndrome (AIDS). On rare occasions, however, CMV diseases can be seen in apparently immunocompetent
HIV/AIDS in the context of culture: selection of ethnocultural communities for study in Canada.: Can J Public Health. 1996 May-Jun;87 Suppl 1:S11-4, S11-5. Unique Identifier : AIDSLINE MED/96321424; Cappon P; Adrien A; Godin G; Singer SM; Maticka-Tyndale E; Willms DG; Daus T; Laurentian University, Sudbury, ON.; This article reports on the methodology used to select six ethnocultural communities invited to participate in subsequent phases of the project on HIV/AIDS in the context of culture in Canada . Selection was based on quantitative data on demography, qualitative assessment of ethnocu
Participatory aspects in the qualitative research design of phase II of the ethnocultural communities facing AIDS study.: Can J Public Health. 1996 May-Jun;87 Suppl 1:S15-25, S16-27. Unique Identifier : AIDSLINE MED/96321425; Willms D; Singer SM; Adrien A; Godin G; Maticka-Tyndale E; Cappon P; Dept. of Clinical Epidemiology and Biostatistics, Faculty of; Health Sciences, McMaster University, Hamilton, ON.; This paper describes the steps taken in generating and implementing a qualitative research design for Phase II of the Ethnocultural Communities Facing AIDS Study. Theoretically framed by the macro-level, sociocultural model of health behaviour developed by Kleinman, the methodological procedures are an adaptation of S
Many voices--sociocultural results of the ethnocultural communities facing AIDS study in Canada.: Can J Public Health. 1996 May-Jun;87 Suppl 1:S26-32, S28-35. Unique Identifier : AIDSLINE MED/96321426; Singer SM; Willms DG; Adrien A; Baxter J; Brabazon C; Leaune V; Godin G; Maticka-Tyndale E; Cappon P; Centre for Human Settlements, University of British Columbia,; Vancouver.; This paper presents the results of Phase II of the Ethnocultural Communities Facing AIDS Study, the sociocultural investigation of factors contributing to risk behaviour associated with HIV/AIDS in six ethnocultural communities in Canada in three urban sites. In Vancouver, the Sout
HIV/AIDS in the context of culture [editorial]: Can J Public Health. 1996 May-Jun;87 Suppl 1:S3. Unique Identifier : AIDSLINE MED/96321422; de Burger R
Understanding use of condoms among Canadian ethnocultural communities: methods and main findings of the survey.: Can J Public Health. 1996 May-Jun;87 Suppl 1:S33-7, S36-41. Unique Identifier : AIDSLINE MED/96321427; Godin G; Maticka-Tyndale E; Adrien A; Singer SM; Willms D; Cappon P; Bradet R; Daus T; LeMay G; Research Group on Psychosocial Aspects of Health Behavior, School; of Nursing, Laval University, Quebec (QC).; The aim of this study was to understand the intention to use a condom for each instance of sexual intercourse with a new partner in three of Canada s non-dominant ethnocultural communities: Latin American (N = 346), English-speaking Caribbean (N = 358), and South Asian (N = 355). All respondents were recruited from mu
Canadian ethnocultural communities facing AIDS: overview and summary of survey results from phase III.: Can J Public Health. 1996 May-Jun;87 Suppl 1:S38-43, S42-8. Unique Identifier : AIDSLINE MED/96321428; Maticka-Tyndale E; Godin G; LeMay G; Adrien A; Singer SM; Willms D; Cappon P; Bradet R; Dept. of Sociology and Anthropology, University of Windsor, ON.; This paper describes the survey results reporting demographic profiles, behaviours, opinions, beliefs, attitudes, and intentions related to condom use for three Canadian ethnocultural communities (Latin American, English-speaking Caribbean and South Asian) participating in the Ethnocultural Communities Facing AIDS Stu
Overview of the Canadian study on the determinants of ethnoculturally specific behaviours related to HIV/AIDS.: Can J Public Health. 1996 May-Jun;87 Suppl 1:S4-10. Unique Identifier : AIDSLINE MED/96321423; Adrien A; Godin G; Cappon P; Singer SM; Maticka-Tyndale E; Willms D; Departement de sante publique, Hopital general de Montreal,; QC.; Canada s population is composed of heterogenous ethnocultural communities. There is a need for information and educational initiatives on HIV and AIDS directed specifically at these communities. For such interventions to be effective we must determine the existing personal and sociocultural factors related to HIV tran
Five conversations: reflections of stakeholders on the impact of the ethnocultural communities facing AIDS study.: Can J Public Health. 1996 May-Jun;87 Suppl 1:S44-8, S49-53. Unique Identifier : AIDSLINE MED/96321429; Willms D; Bhatia R; Lowe J; Niemi F; Stewart D; Westmoreland-Traore J; Department of Clinical Epidemiology and Biostatistics, Faculty of; Health Sciences, McMaster University, Hamilton, Canada.; This paper reports on issues identified in conversations held between one of the Ethnocultural Communities Facing AIDS Study (ECFA) investigators and five stakeholders associated with this experiment in collaborative and participatory research. The stakeholders reflect on their experiences in partnering with universit
Coming out: an overlooked concept.: Clin Nurse Spec. 1996 Jan;10(1):2-5, 56. Unique Identifier : AIDSLINE MED/96336957; Saddul RB Jr; WITH CURRENT TRENDS in human immunodeficiency virus (HIV) early intervention moving more toward primary care, more and more advanced practice nurses (APNs) are providing primary care to people with HIV. Because almost half of new cases of acquired immune deficiency syndrome continue to have homosexual or bisexual cont
Recruitment of women into research studies: a nursing perspective [see comments]: Clin Nurse Spec. 1996 Jan;10(1):25-8. Unique Identifier : AIDSLINE MED/96336963; Kelly PJ; Cordell JR; RESEARCH TRIALS HAVE historically underrepresented women, especially women of ethnic minority and lower socioeconomic groups. Although these populations of women are disproportionately afflicted with human immunodeficiency virus (HIV), HIV studies have followed this pattern of underrepresentation. Nurses working in HI
Risk taking by health care workers.: Clin Nurse Spec. 1996 Jan;10(1):30-7. Unique Identifier : AIDSLINE MED/96336965; Sulzbach-Hoke LM; HEALTH CARE WORKERS (HCWs) are at risk for acquiring infections such as human immunodeficiency virus, hepatitis B virus, hepatitis C, and tuberculosis from blood and body fluids. The Centers for Disease Control established guidelines known as universal precautions (UPs) to prevent transmission of blood-borne pathogens
Genetic instability as a basis for transformation of human lymphocytes infected with human retrovirus.: Cancer Detect Prev. 1996;20(2):87-93. Unique Identifier : AIDSLINE MED/96253398; Maruyama K; Mochizuki S; Kawamura K; Koshikawa N; Chiba Cancer Center Research Institute, Japan.; T cell lines (Coculture-14, Coculture-5) derived from human T-cell leukemia virus type I (HTLV-I)-seronegative persons acquired interleukin-2 ( IL-2 )-dependent continuous growth capacity (immortalized) following in vitro HTLV-I infection. They showed structural abnormal
HIV and AIDS: where is the epidemic going?: Bull World Health Organ. 1996;74(2):121-9. Unique Identifier : AIDSLINE MED/96316496; Mertens TE; Low-Beer D; Division of Development of Policy, World Health Organization,; Geneva, Switzerland.; Routine surveillance of HIV (human immunodeficiency virus) infection and AIDS has been established over the past decade in many countries around the world. HIV estimates derived from empirical data are essential to the assessment of the HIV situation in different parts of the world and trends are used in tracking the
The relation between thyroid function and nutritional status in HIV-infected patients.: Clin Endocrinol (Oxf). 1996 Jan;44(1):53-8. Unique Identifier : AIDSLINE MED/96264383; Ricart-Engel W; Fernandez-Real JM; Gonzalez-Huix F; del Pozo M; Mascaro J; Garcia-Bragado F; Department of Internal Medicine, Hospital de Girona Dr Josep; Trueta, Spain.; OBJECTIVE: The effects of human immunodeficiency virus (HIV) infection on thyroid function have been reported in only a few studies with discrepant results. The aim of this study was to assess the relation between nutritional status and thyroid function in HIV infected patients. DESIGN: Prospective, cross-sectional st
CD8+ lymphocyte phenotype and cytokine production in long-term non-progressor and in progressor patients with HIV-1 infection.: Clin Exp Immunol. 1996 Aug;105(2):220-4. Unique Identifier : AIDSLINE MED/96332554; Zanussi S; Simonelli C; D'Andrea M; Caffau C; Clerici M; Tirelli U; DePaoli P; Department of Microbiology-Immunology-Virology, C.R.O. Aviano,; Italy.; In most HIV-1-infected patients, clinical and immunological progression develops within a few years. Few infected people, termed long-term non-progressors (LTNP), remain healthy and immunologically stable for a long time. The factors governing the maintenance of this condition are not well known, but it is conceivable
Reversal of the inhibitory effects of HIV-gp120 on CD4+ T cells by stimulation through the CD28 pathway.: Clin Exp Immunol. 1996 Aug;105(2):225-30. Unique Identifier : AIDSLINE MED/96332555; Faith A; Yssel H; O'Hehir RE; Lamb JR; Department of Immunology, St Mary's Hospital Medical School,; London, UK.; The effects of exposure to HIV-gp120 on proliferation and cytokine production by T cell lines were investigated. T cell lines were generated by stimulation of peripheral blood mononuclear cells from several healthy donors with cross-linked anti-CD3 antibodies and IL-2 .
Immunoregulation in onchocerciasis: predominance of Th1-type responsiveness to low molecular weight antigens of Onchocerca volvulus in exposed individuals without microfilaridermia and clinical disease.: Clin Exp Immunol. 1996 Aug;105(2):245-53. Unique Identifier : AIDSLINE MED/96332558; Luder CG; Schulz-Key H; Banla M; Pritze S; Soboslay PT; Institute of Tropical Medicine, University of Tubingen, Germany.; Chronic and generalized onchocerciasis is associated with suppression of the parasite-specific cellular responsiveness, while exposed individuals without parasitological and clinical evidence of infection (endemic normals) display prominent cellular reactivity to Onchocerca volvulus antigens (OvAg). In order to identi
Predominance of a type 2 intratumoural immune response in fresh tumour-infiltrating lymphocytes from human gliomas.: Clin Exp Immunol. 1996 Aug;105(2):344-52. Unique Identifier : AIDSLINE MED/96332573; Roussel E; Gingras MC; Grimm EA; Bruner JM; Moser RP; Department of Thoracic Surgery, University of Texas M. D.; Anderson Cancer Centre, Houston, USA.; Increasing evidence suggests the existence of polarized human T cell responses described as Th1-type (promoting cell-mediated immunity) and Th2-type (promoting humoral immunity), characterized by a dominant production of either interferon-gamma (IFN-gamma) or IL-4, respectively. Little is known about the intratumoural
Predictors of intention to be sexually active among Tanzanian school children.: East Afr Med J. 1996 Apr;73(4):218-24. Unique Identifier : AIDSLINE MED/96321449; Klepp KI; Ndeki SS; Thuen F; Leshabari M; Seha AM; Centre for International Health, University of Bergen, Norway.; This paper presents the results from a study of human immunodeficiency virus/AIDS risk behaviour conducted among primary school children in the Kilimanjaro and Arusha regions of northern Tanzania . The study was guided by the theory of reasoned action, and the decision to have or
Clinical and pathological studies in horses with hepatic disease.: Equine Vet J. 1996 Mar;28(2):146-56. Unique Identifier : AIDSLINE MED/96259834; West HJ; Department of Veterinary Clinical Science, University of; Liverpool Veterinary Field Station, Neston, South Wirral, UK.; In horses with hepatic necrosis, lipidosis, neoplasia and cirrhosis, progression of the disease was studied by serial measurements of total serum bile acid concentrations and of plasma glutamate dehydrogenase (GD) and gamma glutamyl transferase (gamma GT) and by liver biopsy. Plasma ammonia concentrations were signifi
Effects of equine influenza and tetanus vaccination on pulmonary function in normal and chronic obstructive pulmonary disease affected horses.: Equine Vet J. 1996 Mar;28(2):157-60. Unique Identifier : AIDSLINE MED/96259835; Dixon PM; McGorum BC; Marley C; Halliwell RE; Matthews AG; Morris JR; Department of Veterinary Clinical Studies, Midlothian,; Kilmarnock, UK.
Insights on immunological aging derived from the T lymphocyte cellular senescence model.: Exp Gerontol. 1996 Jan-Apr;31(1-2):21-7. Unique Identifier : AIDSLINE MED/96260660; Effros RB; Department of Pathology, UCLA School of Medicine 90024-1732, USA.; A human T cell culture system has been developed to study cellular senescence in a manner analogous to that used for fibroblasts. Using this system, several markers of replicative senescence have been identified. Evidence is provided to show that new insights into the immune deficiency of aging as well as HIV infectio
The changing epidemiology of fungal infections: are the lipid-forms of amphotericin B an advance?: Eur J Haematol Suppl. 1996;57:12-7. Unique Identifier : AIDSLINE MED/96292916; Herbrecht R; Department of Oncology and Haematology, Hopitaux Universitaires; de Strasbourg, France.; The incidence of invasive fungal infections is increasing and new fungal species are emerging as important pathogens. In cancer patients, the main risk factor for the development of systemic fungal disease is severe, prolonged neutropenia. Other factors, such as mucosal damage, presence of a central venous line, immun
Uncleaved env gp160 of human immunodeficiency virus type 1 is degraded within the Golgi apparatus but not lysosomes in COS-1 cells.: FEBS Lett. 1996 Jul 15;390(1):15-20. Unique Identifier : AIDSLINE MED/96314540; Kimura T; Nishikawa M; Fujisawa J; Department of Microbiology, Kansai Medical University, Osaka,; Japan.; The fate of newly synthesized human immunodeficiency virus type 1 env gp160 was examined in COS-1 cells. The results of morphological chase experiments involving cycloheximide demonstrated that gp160 was retained in the Golgi apparatus for longer than the half-life of the molecule. The degradation of gp160 was insensi
A model for DNA polymerase translocation: worm-like movement of DNA within the binding cleft.: FEBS Lett. 1996 Jul 15;390(1):6-9. Unique Identifier : AIDSLINE MED/96314538; Wlassoff WA; Dymshits GM; Lavrik OI; Institute of Cytology and Genetics, Novosibirsk, Russian; Federation. AUSMA@genome.nsk.su; On the basis of recent results, we propose a model for DNA polymerase translocation along DNA. Human immunodeficiency virus reverse transcriptase is taken as an example. According to the model, movement of the enzyme is the result of transition of the enzyme-bound DNA from the A- to B-form which is accompanied by leng
[The role of cytokines in viral infections]: G Batteriol Virol Immunol. 1994 Jan-Dec;86(1-12):65-78. Unique Identifier : AIDSLINE MED/96308200; Cavallo R; Cavallo F; Cavallo G; Istituto di Microbiologia dell'Universita di Torino.; The immune response to viral infections is a combination of many events: viral antigen presentation to the immune system, proliferation of specific lymphocytes, cytokine intervention. This review describes the virus-cell relationship contributing to the latency state in viral infections (especially in AIDS) and cytoki
[Therapeutic potential of ozone--possible side-effects]: Harefuah. 1996 Mar 1;130(5):327-30. Unique Identifier : AIDSLINE MED/96316518; Avivi I; Blumenfeld I; Blumenfeld Z
[Diseases of the gallbladder and biliary tract in patients with AIDS]: Harefuah. 1996 Mar 1;130(5):330-2. Unique Identifier : AIDSLINE MED/96316519; Regev A; Pomeranz I; Leichtmann G; Novis B
[Physiologic importance of dehydroepiandrosterone]: Harefuah. 1996 Mar 1;130(5):353-6. Unique Identifier : AIDSLINE MED/96316526; Danenberg HD; Ben-Yehuda A
[New treatments in HIV]: Harefuah. 1996 Apr 1;130(7):467-70. Unique Identifier : AIDSLINE MED/96304074; Turner D; Fried M; Peters B; Konecny P; Yust I
Sexually transmitted diseases in South Africa.: Genitourin Med. 1996 Jun;72(3):160-71. Unique Identifier : AIDSLINE MED/96334933; Pham-Kanter GB; Steinberg MH; Ballard RC; National AIDS Research Programme, Medical Research Council,; Johannesburg, South Africa.; AIM: To review the epidemiology of and data collection for sexually transmitted diseases (STDs) in South Africa . METHODS: Literature published since 1980 on STDs in South Africa were complied and evaluated. Historical reports and salient unpublished literature were also used in th
The haemolytic uraemic syndrome in patients with AIDS.: Genitourin Med. 1996 Jun;72(3):172-5. Unique Identifier : AIDSLINE MED/96334934; Kelleher P; Severn A; Tomson C; Lucas S; Parkin J; Pinching A; Miller R; Department of Immunology, St Bartholomew's Hospital Medical; College, London.; OBJECTIVE: Thrombotic microangiopathies have been increasingly recognised in HIV infection. The contribution of haemolytic uraemic syndrome (HUS) has not received as much emphasis as other members of the thrombotic microangiopathies. We describe the clinical features and prognosis of HUS in a group of patients with AI
Active syphilis in HIV infection: a multicentre retrospective survey. The German AIDS Study Group (GASG).: Genitourin Med. 1996 Jun;72(3):176-81. Unique Identifier : AIDSLINE MED/96334935; Schofer H; Imhof M; Thoma-Greber E; Brockmeyer NH; Hartmann M; Gerken G; Pees HW; Rasokat H; Hartmann H; Sadri I; Emminger C; Stellbrink HJ; Baumgarten R; Plettenberg A; Klinikum der Johann Wolfgang Goethe-Universitat, Zentrum der; Dermatologie, Frankfurt am Main, Germany.; OBJECTIVE: To study syphilis in HIV infection focusing on immunocompromised patients with an atypical or aggressive clinical course of syphilis, inappropriate serological reactions or an unreliable response to therapy. STUDY DESIGN: A multicentre retrospective chart review using a standardised questionnaire for all pa
Occult miliary tuberculosis in advanced HIV disease [clinical conference]: Genitourin Med. 1996 Jun;72(3):187-92. Unique Identifier : AIDSLINE MED/96334938; Corbett EL; Davidson RN; Lucas SB; Shetty N; Miller RF; Department of Medicine, Camden & Islington Community Health; Services NHS Trust, Middlesex Hospital Site, London.
A case control study of HIV seroconversion in gay men, 1988-1993: what are the current risk factors?: Genitourin Med. 1996 Jun;72(3):193-6. Unique Identifier : AIDSLINE MED/96334939; Williams DI; Stephenson JM; Hart GJ; Copas A; Johnson AM; Williams IG; Department of Sexually Transmitted Diseases, University College; London Medical School, UK.; OBJECTIVE: To investigate current risk factors for HIV seroconversion among homo/bisexual men. DESIGN: Matched case control study in a large STD clinic in central London. Data on risk factors were obtained by case note review. METHODS: Fifty-six cases who had at least one negative HIV test followed by a positive test
Hepatitis C virus infection in a male homosexual cohort: risk factor analysis.: Genitourin Med. 1996 Jun;72(3):213-6. Unique Identifier : AIDSLINE MED/96334942; Ndimbie OK; Kingsley LA; Nedjar S; Rinaldo CR; Department of Pathology, University of Pittsburgh, PA.; BACKGROUND: Hepatitis C virus (HCV) infection is a major cause of morbidity throughout the world. Parenteral exposure to infected blood accounts for the majority of cases. Sexual transmission is suggested by the higher prevalence of infection in sex workers and homosexual men. Sexual practices which contribute to HCV
An interview based approach to seeking user views in genitourinary medicine.: Genitourin Med. 1996 Jun;72(3):223-6. Unique Identifier : AIDSLINE MED/96334946; Evans D; Farquhar C; Institute for Health Policy Studies, University of Southampton,; UK.; OBJECTIVES: To assess user and potential user views on the appropriateness, nature and quality of genitourinary medicine (GUM) provision in Bristol, UK and to develop a model for ongoing user consultation by GUM providers and purchasers. DESIGN: This qualitative study was based on semi-structured interviews with servi
CD31 (PECAM-1) is a differentiation antigen lost during human CD4 T-cell maturation into Th1 or Th2 effector cells.: Immunology. 1996 May;88(1):110-5. Unique Identifier : AIDSLINE MED/96273487; Demeure CE; Byun DG; Yang LP; Vezzio N; Delespesse G; Centre de Recherche Louis-Charles Simard, University of; Montreal, Canada.; The CD31 antigen (PECAM-1) has been reported to be a stable marker for a human CD4 T-cell subpopulation unable to produce interleukin-4 (IL-4). We show here that CD31 expression is not stable inasmuch as CD4 T-cell lines and clones derived from cell-sorted neonatal CD31+ cells lose CD31 upon repetitive cycles of stimu
Repopulation of blood lymphocyte sub-populations in rheumatoid arthritis patients treated with the depleting humanized monoclonal antibody, CAMPATH-1H.: Immunology. 1996 May;88(1):13-9. Unique Identifier : AIDSLINE MED/96273473; Brett S; Baxter G; Cooper H; Johnston JM; Tite J; Rapson N; Biology Division, Wellcome Research Laboratories, Beckenham,; Kent, UK.; Patients with severe rheumatoid arthritis who had failed treatment with conventional therapies were treated with a course of five or 10 daily intravenous infusions of CAMPATH-1H, a humanized antibody against the CD52 antigen, resulting in profound depletion of peripheral blood mononuclear cells. During the subsequent
HIV-1 envelope glycoprotein gp120 down-regulates CD4 expression in primary human macrophages through induction of endogenous tumour necrosis factor-alpha.: Immunology. 1996 May;88(1):55-60. Unique Identifier : AIDSLINE MED/96273479; Karsten V; Gordon S; Kirn A; Herbein G; I.N.S.E.R.M. Unit 74, Louis Pasteur University, Strasbourg,; France.; Among immunological abnormalities present in human immunodeficiency virus type 1 (HIV-1)-infected individuals are dysregulation of cytokine production and CD4 down-regulation in both T-helper cells and monocytes/macrophages. The HIV-1 envelope glycoprotein 120 (gp120) has the ability to induce different cytokines in p
Heat-shock protein expression on the membrane of T cells undergoing apoptosis.: Immunology. 1996 May;88(1):6-12. Unique Identifier : AIDSLINE MED/96273472; Poccia F; Piselli P; Vendetti S; Bach S; Amendola A; Placido R; Colizzi V; Department of Biology, University of Rome Tor Vergata, Italy.; Heat-shock proteins (hsp) represent a highly conserved family of proteins, normally localized in the cytoplasm and nucleus, whose expression is induced in situations involving cell stress. This paper reports the unusual translocation of hsp to the cell membrane of T cells undergoing apoptosis. We observed that glucoco
In vitro anti human immunodeficiency virus activity of mangrove plants.: Indian J Med Res. 1996 May;103:278-81. Unique Identifier : AIDSLINE MED/96267213; Premanathan M; Nakashima H; Kathiresan K; Rajendran N; Yamamoto N; Department of Microbiology, Yamanashi Medical University, Japan.; Mangrove plant extracts were screened in vitro against human immunodeficiency virus (HIV) on MT-4 cells. HIV infected MT-4 cells were cultured for five days in the presence of the extract, at various concentrations. Anti-HIV activity was evaluated by tetrazolium-based colorimetric assay. Seven extracts were found effe
Mechanisms of immune suppression in patients with head and neck cancer: influence on the immune infiltrate of the cancer.: Int J Cancer. 1996 Jul 29;67(3):333-8. Unique Identifier : AIDSLINE MED/96321016; Young MR; Wright MA; Lozano Y; Matthews JP; Benefield J; Prechel MM; Research Service, Hines VA Hospital, IL 60141, USA.; Freshly excised human head and neck cancers (219 primary cancers; 64 metastatic lymph node cancers) were analyzed for the immune inhibitory mediators released from the cancer tissues and the immune infiltrate within the tumor. Significant levels of the immune inhibitory mediators transforming growth factor-beta (TGF-b
Alterations of the thymic selection process in transgenic mice expressing SV40 large T antigen.: Int J Cancer. 1996 Jul 29;67(3):399-404. Unique Identifier : AIDSLINE MED/96321026; Lee WH; Seo JS; Transgenic Mice Center, Seoul National University College of; Medicine, Korea.; We generated SV40 T antigen transgenic mice (lines SVT125, SVT127, and SVT248) which developed unique thymic carcinomas originating from thymic cortical epithelial cells. In these mice we observed alterations in the thymic selection process not reported before in SV40 T antigen transgenic mice. Along with tumor cell g
Polyoma tumor development in neonatally polyoma-virus-infected CD4-/- and CD8-/- single knockout and CD4-/-8-/- double knockout mice.: Int J Cancer. 1996 Jul 29;67(3):405-8. Unique Identifier : AIDSLINE MED/96321027; Berke Z; Wen T; Klein G; Dalianis T; Division of Clinical Virology, Karolinska Institute, Huddinge; University Hospital, Sweden.; CD4-/- or CD8-/- single knockout as well as CD4-/-8-/- double knockout mice were infected with polyoma virus as newborns or 1 week after birth. The animals were followed for tumor development and virus persistence. Double knockout mice developed tumors at a higher incidence (29%) than either the CD8-/- or CD4-/- singl
Expression of the endogenous retrovirus ERV3 (HERV-R) during induced monocytic differentiation in the U-937 cell line.: Int J Cancer. 1996 Jul 29;67(3):451-6. Unique Identifier : AIDSLINE MED/96321035; Larsson E; Venables PJ; Andersson AC; Fan W; Rigby S; Botling J; Oberg F; Cohen M; Nilsson K; Department of Pathology, Uppsala University Hospital, Sweden.; ERV3 (HERV-R) is a complete human endogenous retrovirus located on the long arm of chromosome 7. LTR-env-gene-spliced mRNA of 9 and 3.5 Kb is widely expressed in human tissues and cells, but gag-pol mRNA has not been found. Further, the env gp70 gene contains an open reading frame throughout its length and its express
A comparison of the psychosocial aspects of AIDS and cancer-related bereavement.: Int J Psychiatry Med. 1996;26(1):35-49. Unique Identifier : AIDSLINE MED/96336149; Kelly B; Raphael B; Statham D; Ross M; Eastwood H; McLean S; O'Loughlin B; Brittain K; University of Queensland, Brisbane, Australia.; OBJECTIVE: This study compares the psychological symptoms and bereavement distress of individuals bereaved by AIDS with a group bereaved by a cancer death, and addresses the question of whether an AIDS death is associated with a higher rate of adverse psychosocial factors that may increase risk of psychological morbid
[Demand and HIV testing prescription in primary care. Registry of the network of sentinel physicians from Castilla y Leon in 1991, 1992, and 1993]: Gac Sanit. 1996 Jan-Feb;10(52):25-33. Unique Identifier : AIDSLINE MED/96233323; Vega Alonso AT; Gil Costa M; Ruiz Cosin C; Servicio de Epidemiologia, Direccion General de Salud Publica; y Asistencia, Consejeria de Sanidad y Bienestar Social,; Valladolid.; OBJECTIVE: the objective of this descriptive study is to improve the knowledge about the use and demand of HIV test in general population in Primary Health Care, as well as to detect lacks in general medicine related to HIV/AIDS. METHOD: from 1991 to 1993, the Red de Medicos Centinelas de Castilla y Leon, a voluntary
Massage therapy is associated with enhancement of the immune system's cytotoxic capacity.: Int J Neurosci. 1996 Feb;84(1-4):205-17. Unique Identifier : AIDSLINE MED/96234711; Ironson G; Field T; Scafidi F; Hashimoto M; Kumar M; Kumar A; Price A; Goncalves A; Burman I; Tetenman C; Patarca R; Fletcher MA; Touch Research Institute, University of Miami School of Medicine,; Fl, USA.; Twenty-nine gay men (20 HIV+, 9 HIV-) received daily massages for one month. A subset of 11 of the HIV+ subjects served as a within subject control group (one month with and without massages). Major immune findings for the effects of the month of massage included a significant increase in Natural Killer Cell number, N
Economic evaluation of HIV testing among intravenous drug users. An analytic framework and its application to Italy.: Int J Technol Assess Health Care. 1996 Spring;12(2):336-57. Unique Identifier : AIDSLINE MED/96293009; Villari P; Fattore G; Siegel JE; Paltiel AD; Weinstein MC; Istituto di Igiene, Universita degli Studi di Napoli Federico; II, Nuovo Policlinico, Italy.; We performed an economic evaluation of HIV testing among intravenous drug users (IVDUs) in Italy using the analytical framework of cost-effectiveness analysis. A semi-Markov model was developed to calculate costs and life expectancy of a cohort of IVDUs with and without an annual HI
An analysis of the effects of HIV infection in a cohort of intravenous drug users.: Ir Med J. 1996 May-Jun;89(3):112-4. Unique Identifier : AIDSLINE MED/96300758; O'Kelly FD; Bury G; Coombe Healthcare Centre, Dolphin's Barn Street, Dublin.; Intravenous drug use has been a serious problem for Dublin s deprived inner city areas since the late 1970 s. In 1985, a cohort of all known intravenous drug users (IVDUs) was identified in one inner city electoral cohort and has been followed since then. The cohort was identified before the introduction of HIV testin
PPD skin reactivity and anergy in HIV-infected patients in Hawaii.: Hawaii Med J. 1996 Jun;55(6):100-3. Unique Identifier : AIDSLINE MED/96311945; Shikuma CM; Congdon S; Hanks N; Souza S; Kindrick A; Case S; Heath-Chiozzi M; Hawaii AIDS Clinical Research Program, University of Hawaii,; Honolulu 96816, USA.; This study was a prospective screening study for PPD and anergy skin test reactivity in 304 HIV-positive individuals. A PPD positivity rate of 4.1% and an anergy rate of 50.5% were observed. The Hawaii HIV population has a relatively low prevalence of latent TB compared with the high prevalence of TB in the Hawaii pop
Lothian general practitioners, HIV infection and drug misuse: epidemiology, experience and confidence 1988-1993.: Health Bull (Edinb). 1996 May;54(3):258-69. Unique Identifier : AIDSLINE MED/96300737; Bury JK; Ross A; van Teijlingen E; Porter AM; Bath G; Department of General Practice, University of Edinburgh.; BACKGROUND: Lothian has a high prevalence rate of HIV infection associated particularly with injecting drug use in the mid-1980s. During the late 1980s a number of services were introduced to support general practitioners to care for drug users and people with HIV infection. AIM: To ascertain the practice distribution
[Human herpesviruses 6 and 7. Basic principles and possible significance for dermatology]: Hautarzt. 1996 May;47(5):341-50. Unique Identifier : AIDSLINE MED/96259841; Lasch JA; Klussmann JP; Krueger GR; Universitats-Hautklinik, Universitat, Koln.; Primary infection with human herpesviruses 6 and 7 (HHV-6 and HHV-7) during early childhood causes permanent latent infection, usually without any ill effects; only a small percentage of primary infections will lead to exanthem subitum. Like other herpesviruses. HHV-6 and HHV-7 can be reactivated at any time if host d
[Kaposi sarcoma in Caucasian women. Clinical, chemical laboratory and endocrinologic examination of 8 women with HIV associated or classical Kaposi sarcoma (letter)]: Hautarzt. 1996 May;47(5):394. Unique Identifier : AIDSLINE MED/96259853; Schmoeckel C; Dermatohistologisches Labor, Munchen.
Home health, AIDS, and refusal to care.: Home Healthc Nurse. 1996 Mar;14(3):188-94. Unique Identifier : AIDSLINE MED/96343389; Combs EW; Refusing to provide nursing care to patients with human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (AIDS) is an issue with complex ethical, moral and legal implications. As the number of patients with a diagnosis of HIV and AIDS increases in rural and urban areas, nurses and other healthcare
Health effects of experiences of sexual violence for women with abusive partners.: Health Care Women Int. 1995 Nov-Dec;16(6):563-76. Unique Identifier : AIDSLINE MED/96339513; Eby KK; Campbell JC; Sullivan CM; Davidson WS 2nd; We assessed the incidence of sexual violence, physical violence, physical health symptoms, gynecological symptoms, and risk behaviors for contracting an STD or HIV infection in women who had used a shelter for women with abusive partners. In addition, we investigated the relationships between sexual violence and the f
Impact of HIV/AIDS on women in the United States: challenges of primary and secondary prevention.: Health Care Women Int. 1995 Nov-Dec;16(6):577-95. Unique Identifier : AIDSLINE MED/96339514; Stevens PE; Women are the fastest growing group in the United States being infected with HIV. Although the majority of people with AIDS in the United States are men, AIDS is increasing almost four times as fast among women. Yet women remain understudied, underreport, and underdiagnosed. There are
Relative growth measurement of Candida species in a single concentration of fluconazole predicts the clinical response to fluconazole in HIV infected patients with oral candidosis.: J Antimicrob Chemother. 1996 Feb;37(2):275-83. Unique Identifier : AIDSLINE MED/96233034; Cartledge JD; Midgley J; Gazzard BG; Department of HIV/Genito-urinary Medicine, Chelsea & Westminster; Health Care Trust, London, UK.; The growth of 113 Candida spp. isolated prospectively from 104 HIV-positive patients treated for thrush was determined using a single concentration of 3 mg/L (10(-5) M) fluconazole relative to growth in drug free medium. Using a receiver operator characteristic curve, a relativ
Protein orientation in the Tat-TAR complex determined by psoralen photocross-linking.: J Biol Chem. 1996 Jul 19;271(29):16995-8. Unique Identifier : AIDSLINE MED/96291836; Wang Z; Wang X; Rana TM; Department of Pharmacology, Robert Wood Johnson Medical School,; University of Medicine and Dentistry of New Jersey, Piscataway,; New Jersey 08854, USA.; Replication of human immunodeficiency virus type 1 (HIV-1) requires specific interactions of Tat protein with the trans-activation responsive region (TAR) RNA, a 59-base stem-loop structure located at the 5 -end of all HIV mRNAs. We have used a new method based on psoralen photochemistry to identify a specific contact
Molecular cloning and functional characterization of a novel human CC chemokine receptor (CCR5) for RANTES, MIP-1beta, and MIP-1alpha.: J Biol Chem. 1996 Jul 19;271(29):17161-6. Unique Identifier : AIDSLINE GENBANK/U54994; Raport CJ; Gosling J; Schweickart VL; Gray PW; Charo IF; ICOS Corporation, Bothell, Washington 98021, USA.; Chemokines affect leukocyte chemotactic and activation activities through specific G protein-coupled receptors. In an effort to map the closely linked CC chemokine receptor genes, we identified a novel chemokine receptor encoded 18 kilobase pairs downstream of the monocyte chemoattractant protein-1 (MCP-1) receptor (C
Thymidine phosphorylase expression in Kaposi sarcoma.: J Clin Pathol. 1996 May;49(5):400-2. Unique Identifier : AIDSLINE MED/96296184; Dada MA; Boshoff CH; Comley MA; Turley H; Schneider JW; Chetty R; Gatter KC; University Department of Cellular Science, University of Oxford.; AIMS: To examine the immunohistochemical distribution of thymidine phosphorylase (TP) in all clinicopathological subtypes of Kaposi sarcoma. METHODS: Thirty two biopsy specimens of Kaposi sarcoma (29 patients) were studied. Six of these patients represented classic, six endemic, eight HIV associated, seven post-immuno
Quantification of HIV DNA in the brain by PCR: differences between fresh frozen and formalin fixed tissue.: J Clin Pathol. 1996 May;49(5):425-7. Unique Identifier : AIDSLINE MED/96296192; Davison F; An SF; Scaravilli F; Department of Neuropathology, Institute of Neurology, Queen; Square, London.; HIV-1 DNA extracted from frozen and formalin fixed brain tissue can be detected using PCR. This work has been extended by amplifying, using semiquantitative PCR, HIV DNA extracted from frontal lobe tissue of 16 patients with AIDS (eight positive and eight negative for p24 antigen). DNA was amplified using HIV-1 pol ge
The effect of a single mechanical treatment on the subgingival microflora in patients with HIV-associated gingivitis.: J Clin Periodontol. 1996 Mar;23(3 Pt 1):180-7. Unique Identifier : AIDSLINE MED/96265202; Hofer D; Hammerle CH; Grassi M; Mombelli A; University of Bern, School of Dental Medicine, Switzerland.; The purpose of the present study was to investigate the effect of a single episode of scaling and root planing on clinical periodontal parameters and on the subgingival microflora in human immunodeficiency virus (HIV)-positive and HIV-negative subjects. 13 subjects participated and were clinically scored at days -7, 7
Recalcitrant giant molluscum contagiosum in a patient with AIDS.: J Am Acad Dermatol. 1996 Aug;35(2 Pt 1):266-7. Unique Identifier : AIDSLINE MED/96319532; Cronin TA Jr; Resnik BI; Elgart G; Kerdel FA; Department of Dermatology and Cutaneous Surgery, University of; Miami School of Medicine, FL, USA.
Thrombocytopenia caused by fluconazole [letter]: J Am Acad Dermatol. 1996 Aug;35(2 Pt 1):284. Unique Identifier : AIDSLINE MED/96319543; Kalivas J
Pediatric AIDS epidemic reflects the first half million AIDS cases in the U.S.: ASDC J Dent Child. 1996 Mar-Apr;63(2):89-94. Unique Identifier : AIDSLINE MED/96302874; Waldman HB; Department of General Dentistry, State University of New York at; Stony Brook 11794-8706,USA.; Almost seven thousand pediatric AIDS cases with a death rate of 55 percent have been reported. The continuing increase and spread of this epidemic to different child populations and areas in the country is reviewed. Because the progress of this epidemic, pediatric practitioners require an awareness of the evolving epi
In vitro interleukin-5 (IL-5) production by peripheral blood mononuclear cells from patients with drug hypersensitivity.: J Dermatol. 1996 Jun;23(6):379-81. Unique Identifier : AIDSLINE MED/96311964; Mikami C; Ochiai K; Kagami M; Tomioka H; Tanabe E; Department of Dermatology, Sakura Hospital, Toho University; School of Medicine, Chiba, Japan.; It has been shown that CD4+ lymphocytes and eosinophils pathologically infiltrate the dermis in skin eruptions due to hypersensitivity to the administration of certain drugs associated with peripheral eosinophilia. However, the mechanisms involved in drug related skin eruptions with eosinophilia are largely unknown. T
HIV and homophobia: nurses as advocates.: J Adv Nurs. 1995 Oct;22(4):670-6. Unique Identifier : AIDSLINE MED/96111328; Mackereth PA; TENDA (The European Nursing Development Agency), Tameside General; Hospital, Lancashire, England.; Nurses are frequently encouraged in colleges of nursing and professional journals to consider themselves as ideally placed to act as advocates for vulnerable patients. This paper sets out to challenge this assumption in the light of the stigma and discrimination experienced by people affected by HIV and AIDS. Sexualit
HIV and AIDS care: consumers' views on needs and services.: J Adv Nurs. 1995 Oct;22(4):677-86. Unique Identifier : AIDSLINE MED/96111329; Beedham H; Wilson-Barnett J; Division of Nursing and Midwifery, King's College, London,; England.; Increasing numbers of people suffer from HIV infection, in many sectors of society. However, the extent to which health care services meet their needs is open to question. This study aimed to gather consumer views and assess the extent to which care was adequate, through interviews with 85 clients. Their responses wer
Gender-power relations and safer sex negotiation.: J Adv Nurs. 1995 Oct;22(4):687-93. Unique Identifier : AIDSLINE MED/96111330; Taylor BM; HIV Trainer, Oxfordshire, England.; This paper examines the gender-power relations in heterosexual relationships and discusses the implications for women in attempting to negotiate safer sex. Whilst acknowledging the need for examining both male and female perceptions of sexuality, the paucity of research on men s heterosexual experiences has restricted
'Coffee & condoms': the implementation of a sexual health programme in acute psychiatry in an inner city area.: J Adv Nurs. 1996 Feb;23(2):299-304. Unique Identifier : AIDSLINE MED/96209067; Woolf L; Jackson B; South Downs Trust, Brighton, England.; A sexual health programme was set up specifically to target mentally ill individuals, providing a distinct group of interventions designed to assist this specialist cohort in acquiring knowledge, skills, and attitudes that will directly contribute to their mental health. The programme consisted of gender-specific and
The role of computer-based resources in health promotion and disease prevention: implications for college health.: J Am Coll Health. 1996 Jul;45(1):11-7. Unique Identifier : AIDSLINE MED/96300768; Fulop MP; Varzandeh NN; California College Health 2000 at San Diego State University in; California, USA.; The development of the Internet-based World Wide Web communication platform has opened a new avenue for extending the program effectiveness of college health centers. California College Health 2000, a San Diego State University-based HIV prevention project, is collaborating with the university s student health center
Infection control in the dental office: has anything changed?: J Am Dent Assoc. 1996 Jun;127(6):786-90. Unique Identifier : AIDSLINE MED/96267868; Hazelkorn HM; Bloom BE; Jovanovic BD; Program in Dental Public Health, Health Policy and; Administration, School of Public Health East (M/C 923),; University of Illinois at Chicago 60612-7259, USA.; Using data collected in two studies, the authors compare infection control practices used in dental offices in 1988 and 1992. During that time, dentists increased their use of barrier protection but still asked and learned very little about their patients. This lack of communication hinders dentists ability to delive
Struggles with symptoms: women's narratives of managing HIV illness.: J Holist Nurs. 1996 Jun;14(2):142-60. Unique Identifier : AIDSLINE MED/96345367; Stevens PE; The purpose of this research report is to derive a holistic view of the symptom experiences of women living with HIV/AIDS. A racially diverse sample of 38 HIV-infected women participated in in-depth narrative interviews describing their perceptions, evaluations, and responses related to HIV symptoms. Findings suggest
Unrecognized HIV-1 infection in inner-city hospital emergency department patients.: Infect Control Hosp Epidemiol. 1996 Mar;17(3):174-7. Unique Identifier : AIDSLINE MED/96249880; Nagachinta T; Gold CR; Cheng F; Heseltine PN; Kerndt PR; HIV Section/WHFB/CDC, Atlanta, GA 30341, USA.; To determine the prevalence of unrecognized human immunodeficiency virus (HIV)-1 infections in patients presenting to an inner-city hospital emergency department, medical records were reviewed from 1,945 patients diagnosed with diseases not related to HIV or acquired immunodeficiency syndrome. The overall seroprevalen
Comparison of the polymerase chain reaction and serology for the diagnosis of HTLV-I infection.: J Infect. 1996 Mar;32(2):109-12. Unique Identifier : AIDSLINE MED/96332629; van der Ryst E; Smith MS; Visagie HM; Department of Virology, University of the Orange Free State,; Bloemfontein, South Africa.; Human T-lymphotropic virus type I (HTLV-I) is associated with tropical spastic paraparesis (TSP) and adult T-cell leukaemia/ lymphoma (ATL). HTLV-I seroconversion may not take place for many years after infection and some patients develop relatively low concentrations of antibodies that are difficult to detect by mean
Risks and benefits of aerosolized pentamidine and cotrimoxazole in primary prophylaxis of Pneumocystis carinii pneumonia in HIV-1-infected patients: a two-year Italian multicentric randomized controlled trial. The Italian PCP Study Group.: J Infect. 1996 Mar;32(2):123-31. Unique Identifier : AIDSLINE MED/96332632; Rizzardi GP; Lazzarin A; Musicco M; Frigerio D; Maillard M; Lucchini M; Moroni M; Institute of Internal Medicine, Infectious Diseases and; Immunopathology, University of Milan, Italy.; We randomized 220 HIV-1-infected subjects to receive aerosolized pentamidine (300 mg/4 weeks) or orally trimethoprim-sulfamethoxazole (320-1600 mg/day) for primary prophylaxis of Pneumocystis carinii pneumonia (PCP), and evaluated PCP and toxoplasmic encephalitis (TE) occurrence and survival. Patients developing toxic
Visceral leishmaniasis in HIV infected patients: treatment with high dose liposomal amphotericin B (AmBisome).: J Infect. 1996 Mar;32(2):133-7. Unique Identifier : AIDSLINE MED/96332633; Russo R; Nigro LC; Minniti S; Montineri A; Gradoni L; Caldeira L; Davidson RN; Istituto di Malattie Infettive, Universita di Catania.; Visceral leishmaniasis (VL) in patients coinfected with human immunodeficiency virus (HIV) is often atypical, and characteristically relapses after treatment. We treated 10 HIV infected patients (9 men) with parasitologically confirmed VL with liposomal amphotericin B (AmBisome : L-AMB) at a dose of 4 mg/kg/day on day
Multidrug-resistant tuberculosis in an HIV-positive man in the United Kingdom.: J Infect. 1996 Mar;32(2):153-4. Unique Identifier : AIDSLINE MED/96332638; Kelleher P; Coakley J; Anderson J; Moore-Gillon J; St. Bartholomew's Hospital, London, UK.; Multidrug-resistant Mycobacterium tuberculosis infection (MDR-TB) in those who are HIV positive has until now been largely a North American phenomenon. We report a fatal case in London.
Mixed cerebral pathology in AIDS patients [letter]: J Infect. 1996 Mar;32(2):174. Unique Identifier : AIDSLINE MED/96332648; Laing RB; Brettle RP
Predominance of codon 215 mutation in reverse transcriptase-coding region of 3'-azido-3'-deoxythymidine (AZT)-resistant HIV-1 isolates after long-term AZT therapy.: Kansenshogaku Zasshi. 1995 Nov;69(11):1278-85. Unique Identifier : AIDSLINE MED/96111756; Kondo M; Department of Virology, Kanagawa Prefectural Public Health; Laboratory, Japan.; Among human immunodeficiency type 1 viruses (HIV-1) isolated during long-term 3 -azido-3 -deoxythymidine ( AZT ) therapy, 4 condoms (Asp67, Lys70, Thr215, and Lys219) in the HIV-1-reverse transcriptase (RT)-coding region have been considered to be relat
[Mechanism of airway inflammation in patients with asthma]: Nippon Naika Gakkai Zasshi. 1996 Feb 10;85(2):174-7. Unique Identifier : AIDSLINE MED/96308347; Morita Y
[Role of cytokines in pathophysiology of asthma]: Nippon Naika Gakkai Zasshi. 1996 Feb 10;85(2):184-8. Unique Identifier : AIDSLINE MED/96308349; Ishioka S
Detection of HIV-1 proviral DNA by polymerase chain reaction: a preliminary study in Bangkok.: J Med Assoc Thai. 1996 Mar;79(3):142-8. Unique Identifier : AIDSLINE MED/96300882; Sutthent R; Foongladda S; Likanonskul S; Tunsupasawasdeekul S; Roongpisuthipong A; Chearskul S; Raktham S; Louisirirotchanakul S; Wasi C; Department of Microbiology, Faculty of Medicine, Siriraj; Hospital, Mahidol University, Bangkok, Thailand.; Nested polymerase chain reaction (nested PCR) was used to separately amplify part of gag, pol, and env genes of human immunodeficiency virus type 1 (HIV-1) to evaluate that primer specific to either gag (SK380/390&SK38/39), pol (JA17/18&JA19/20), or env (JA9/10&JA11/12) genes is suitable for HIV-1 PCR based
CD4 + T counts with a course of antituberculous therapy in healthy and HIV-infected patients.: J Med Assoc Thai. 1996 Apr;79(4):246-8. Unique Identifier : AIDSLINE MED/96300899; Saenghirunvattana S; Department of Medicine, Faculty of Medicine, Ramathibodi; Hospital, Bangkok, Thailand.; A prospective study of CD4 + T lymphocytes with a course of treatment on 20 HIV-infected patients with active tuberculosis receiving antituberculous drugs was compared with 30 non HIV-infected patients with active tuberculosis. The CD4 + T cell counts among non HIV-infected patients were 510 +/- 409 and increased to 6
Effect of isoniazid prophylaxis on incidence of active tuberculosis among Thai HIV-infected individuals.: J Med Assoc Thai. 1996 May;79(5):285-7. Unique Identifier : AIDSLINE MED/96300907; Saenghirunvattana S; Department of Medicine, Faculty of Medicine, Ramathibodi; Hospital, Bangkok, Thailand.; A prospective comparative study was conducted to determine the effect of isoniazid prophylaxis on the incidence of active tuberculosis among Thai HIV-infected patients for 1 year. Among those 36 HIV-infected patients without prophylaxis, the incidence of active tuberculosis was 2.7 per cent while in 10 HIV-infected pa
Salmonella lung abscess and bacteraemia in an AIDS patient.: J Med Assoc Thai. 1996 May;79(5):333-6. Unique Identifier : AIDSLINE MED/96300915; Riantawan P; Subhannachart P; Division of Respiratory Medicine, Central Chest Hospital,; Department of Communicable Disease Control, Ministry of Public; Health, Nonthaburi, Thailand.; This report describes a 28-year-old, HIV-infected man presenting with subacute onset of pyrexia, cough, dyspnoea and pleuritic pain. Chest radiograph showed bilateral multiple cavitary lesions. The diagnosis of salmonellosis was secured by isolation of salmonella typhimurium in blood, as well as in sputum. Therapy wit
Bacillary angiomatosis and mycobacterium infection coexisting in a cutaneous lesion in a patient with AIDS.: J Med Assoc Thai. 1996 May;79(5):337-40. Unique Identifier : AIDSLINE MED/96300916; Chiewchanvit S; Chaiwun B; Department of Internal Medicine, Faculty of Medicine, Chiang Mai; University, Thailand.; Bacillary angiomatosis is a recently recognized bacterial infectious disease. It mainly affects patients with acquired immunodeficiency syndrome. The presence of coexistent infections of more than one pathologic process in skin lesions in patients with AIDS has been demonstrated. We report a patient with AIDS in whom
Idiopathic CD4+ lymphocytopenia and systemic vasculitis.: J Intern Med. 1996 Jul;240(1):37-41. Unique Identifier : AIDSLINE MED/96332308; Bordin G; Ballare M; Paglino S; Ravanini P; Dulio D; Malosso MC; Boldorini R; Monteverde A; II Divisione di Medicina Generale, Ospedale Maggiore, Novara,; Italy.; The syndrome defined as idiopathic CD4 lymphocytopenia (ICL) is a rare disease of unknown aetiology, often associated with severe depression of immune defences and the occurrence of opportunistic infections. A case is reported wherein a severe immunodeficiency syndrome with persistent idiopathic CD4+ lymphopenia deve
Paraneoplastic necrotising myelopathy in a case of AIDS with lymphoma [letter]: J Neurol Neurosurg Psychiatry. 1996 Feb;60(2):237. Unique Identifier : AIDSLINE MED/96225756; Drach LM; Enzensberger W; Fabian T; Herrmann G
Age and serum lactate dehydrogenase level are independent prognostic factors in human immunodeficiency virus-related non-Hodgkin's lymphomas: a single-institute study of 96 patients.: J Clin Oncol. 1996 Aug;14(8):2217-23. Unique Identifier : AIDSLINE MED/96326419; Vaccher E; Tirelli U; Spina M; Talamini R; Errante D; Simonelli C; Carbone A; Division of Medical Oncology and AIDS, Centro di Riferimento; Oncologico, Aviano, Italy.; PURPOSE: The role of classical pragnostic factors (ie, age, performance status [PS], stage, extranodal involvement, and serum lactate dehydrogenase [LDH] level) included in the International Index for diffuse large-cell non-Hodgkin s lymphoma (NHL) of the general population is pres
Randomized phase III trial of liposomal daunorubicin versus doxorubicin, bleomycin, and vincristine in AIDS-related Kaposi's sarcoma.: J Clin Oncol. 1996 Aug;14(8):2353-64. Unique Identifier : AIDSLINE MED/96326437; Gill PS; Wernz J; Scadden DT; Cohen P; Mukwaya GM; von Roenn JH; Jacobs M; Kempin S; Silverberg I; Gonzales G; Rarick MU; Myers AM; Shepherd F; Sawka C; Pike MC; Ross ME; Kenneth Norris Jr Comprehensive Cancer Center and Hospital,; University of Southern California, School of Medicine, Los; Angeles, USA. parkashg@hsc.usc.edu; PURPOSE: To compare the safety and efficacy of liposomal daunorubicin (DaunoXome; NeXstar Pharmaceuticals, Inc, Boulder, CO) with a reference regimen of doxorubicin, bleomycin, and vincristine (ABV) in advanced AIDS-related Kaposi s sarcoma (KS). PATIENTS AND METHODS: I
Management of the obstetric patient with tuberculosis.: J Obstet Gynecol Neonatal Nurs. 1996 May;25(4):305-12. Unique Identifier : AIDSLINE MED/96336183; Simpkins SM; Hench CP; Bhatia G; Infection Control Nurse, Santa Clara Valley Medical Center, San; Jose, CA 95128, USA.; Tuberculosis in obstetric patients presents a challenging nursing problem to facilities caring for populations at high risk: the economically disadvantaged, minorities, the foreign-born, and patients with human immunodeficiency virus. Coordination of public health, outpatient, and inpatient services is essential for o
Immunological, genetic, and microbiological study of family members manifesting early-onset periodontitis.: J Periodontol. 1996 Mar;67(3):254-63. Unique Identifier : AIDSLINE MED/96265289; Nakagawa M; Kurihara H; Nishimura F; Isoshima O; Arai H; Sawada K; Nagai A; Murayama Y; Department of Periodontology and Endodontology, Okayama; University Dental School, Japan.; From the standpoint of host-parasite interactions, family studies help us understand the host defensive factors and the molecular mechanisms involved in the periodontal immune response. In this study, we report the immunological profile of host-defensive functions, human leukocyte antigen (HLA) phenotypes, and the mic
Host defensive functions in a family manifesting early-onset periodontitis.: J Periodontol. 1996 Apr;67(4):433-42. Unique Identifier : AIDSLINE MED/96310260; Arai H; Chihara T; Takahashi K; Nagai A; Akutsu I; Takashiba S; Nishimura F; Kurihara H; Murayama Y; Department of Periodontology and Endodontology, Okayama; University Dental School, Japan.; Family case studies help us identify host risk factors in periodontal disease. In this study we examine a family consisting of a mother (40 years old, with rapidly progressive periodontitis), her elder daughter (14 years old, with localized juvenile periodontitis), and younger daughter (13 years old, with simple gingi
AIDS in San Francisco. The Medicine Gilliland Travelling Fellowship 1995.: J R Coll Physicians Lond. 1996 Mar-Apr;30(2):178-81. Unique Identifier : AIDSLINE MED/96260850; Jackson DH; North Hampshire Hospital, Winchester.
AIDS-related malignancies.: J R Soc Med. 1996 Jan;89(1):35P-6P. Unique Identifier : AIDSLINE MED/96264192; Spittle MF; Middlesex Hospital, London, England.; The management of AIDS-related malignancies demands that the cancer must be treated in the context of patients already suffering from a fatal disease. Management must be problem-orientated. The standard cancer treatment of such a patient may not be appropriate in the AIDS setting. The AIDS related malignancies are Kap
Pyrrolobenzothiazepinones and pyrrolobenzoxazepinones: novel and specific non-nucleoside HIV-1 reverse transcriptase inhibitors with antiviral activity.: J Med Chem. 1996 Jul 5;39(14):2672-80. Unique Identifier : AIDSLINE MED/96298048; Campiani G; Nacci V; Fiorini I; De Filippis MP; Garofalo A; Greco G; Novellino E; Altamura S; Di Renzo L; Dipartimento Farmaco Chimico Technologico, Universita di Siena,; Italy.; Two novel classes of pyrrolobenzothiazepinones and pyrrolobenzoxazepinones were investigated as potential anti-AIDS drugs. These compounds were found to inhibit HIV-1 reverse transcriptase (RT) enzyme in vitro and to prevent HIV-1 cytopathogenicity in T4 lymphocytes, without appreciable activity on HIV-2 cytopathic ef
Inhibitors of human immunodeficiency virus type 1 derived from gp41 transmembrane protein: structure--activity studies.: J Med Chem. 1996 Jul 5;39(14):2681-9. Unique Identifier : AIDSLINE MED/96298049; Kazmierski WM; Hazen RJ; Aulabaugh A; StClair MH; Department of Medicinal Chemistry I, Glaxo Wellcome Inc.,; Research Triangle Park, North Carolina 27709, USA.; We synthesized analogues of gp41 (553-590), 1, and evaluated them for their inhibitory activity against HIV-1 in MT4 cell assay (IC50(1) = 2.7 microM). (The numbering scheme for gp41 (e.g., gp41(553-590) for 1) adapted throughout the text is from ref 6.) Gradual truncation of either the N- or C-terminal end of gp41 (5
Structure-based design and synthesis of substituted 2-butanols as nonpeptidic inhibitors of HIV protease: secondary amide series.: J Med Chem. 1996 Jul 5;39(14):2781-94. Unique Identifier : AIDSLINE MED/96298061; Reich SH; Melnick M; Pino MJ; Fuhry MA; Trippe AJ; Appelt K; Davies JF 2nd; Wu BW; Musick L; Agouron Pharmaceuticals, Inc, San Diego, California 92121, USA.; The design, synthesis, and crystallographic analysis of protein-inhibitor complexes is described for a novel series of nonpeptidic HIV protease (HIV Pr)inhibitors. Beginning with a cocrystal structure of a Phe-Pro peptidomimetic bound to the HIV Pr, design was initiated that resulted in the substituted 2-butanol compo
Bis tertiary amide inhibitors of the HIV-1 protease generated via protein structure-based iterative design.: J Med Chem. 1996 Jul 5;39(14):2795-811. Unique Identifier : AIDSLINE MED/96298062; Melnick M; Reich SH; Lewis KK; Mitchell LJ Jr; Nguyen D; Trippe AJ; Dawson H; Davies JF 2nd; Appelt K; Wu BW; Musick L; Gehlhaar DK; Webber S; Shetty B; Kosa M; Kahil D; Andrada D; Agouron Pharmaceuticals Inc. San Diego, California 92121, USA.; A series of potent nonpeptide inhibitors of the HIV protease have been identified. Using the structure of compound 3 bound to the HIV protease, bis tertiary amide inhibitor 9 was designed and prepared. Compound 9 was found to be about 17 times more potent than 3, and the structure of the protein-ligand complex of 9 re
The human immunodeficiency virus type 1 capsid p2 domain confers sensitivity to the cyclophilin-binding drug SDZ NIM 811.: J Virol. 1996 Sep;70(9):5751-7. Unique Identifier : AIDSLINE MED/96323084; Dorfman T; Gottlinger HG; Division of Human Retrovirology, Dana-Farber Cancer Institute,; Boston, Massachusetts 02115, USA.; Human immunodeficiency virus type 1 (HIV-1) specifically incorporates the host cell peptidyl-prolyl isomerase cyclophilin A into virions via contacts with the capsid (CA) domain of the Gag polyprotein Pr55gag. The immunosuppressant drug cyclosporin A and the nonimmunosuppressive cyclosporin A analog SDZ NIM 811 bind t
Transdominant mutants of I kappa B alpha block Tat-tumor necrosis factor synergistic activation of human immunodeficiency virus type 1 gene expression and virus multiplication.: J Virol. 1996 Sep;70(9):5777-85. Unique Identifier : AIDSLINE MED/96323087; Beauparlant P; Kwon H; Clarke M; Lin R; Sonenberg N; Wainberg M; Hiscott J; Lady Davis Institute for Medical Research, Montreal, Quebec,; Canada.; The human immunodeficiency virus type 1 (HIV-1) long terminal repeat (LTR) contains two binding sites for the NF-kappa B/Rel family of transcription factors which are required for the transcriptional activation of viral genes by inflammatory cytokines such as tumor necrosis factor alpha (TNF-alpha) and interleukin-1.
The rev-responsive element negatively regulates human immunodeficiency virus type 1 env mRNA expression in primate cells.: J Virol. 1996 Sep;70(9):5786-90. Unique Identifier : AIDSLINE MED/96323088; Churchill MJ; Moore JL; Rosenberg M; Brighty DW; Department of Gene Expression Sciences, SmithKline Beecham; Pharmaceuticals, King of Prussia, Pennsylvania, USA.; The human immunodeficiency virus type 1 (HIV-1) Rev protein mediates the accumulation of unspliced and singly spliced viral transcripts within the cytoplasm of infected cells, late in the infection cycle, leading to the expression of the viral structural proteins, Gag, Pol, and Env. Rev binds to a complex RNA structur
The zinc finger of nucleocapsid protein of Friend murine leukemia virus is critical for proviral DNA synthesis in vivo.: J Virol. 1996 Sep;70(9):5791-8. Unique Identifier : AIDSLINE MED/96323089; Yu Q; Darlix JL; LaboRetro, Institut National de la Sante et de la Recherche; Medicale U412, Ecole Normale Superieure de Lyon, France.; Nucleocapsid protein NCp10 of murine leukemia virus (MuLV) is encoded by the 3 domain of gag and contains a zinc finger of the form Cys-X2-Cys-X4-His-X4-Cys flanked by basic amino acids. In the course of virus assembly, NCp10 is necessary for core formation, and the zinc finger flanked by the basic residues is requir
Efficient lysis of human immunodeficiency virus type 1-infected cells by cytotoxic T lymphocytes.: J Virol. 1996 Sep;70(9):5799-806. Unique Identifier : AIDSLINE MED/96323090; Yang OO; Kalams SA; Rosenzweig M; Trocha A; Jones N; Koziel M; Walker BD; Johnson RP; AIDS Research Center, Massachusetts General Hospital, Charlestown; 02129, USA.; Numerous studies of human immunodeficiency virus type 1 (HIV-1)-specific cytotoxic T lymphocytes (CTL) have examined their ability to recognize B-cell lines expressing recombinant HIV-1 proteins, but relatively few data regarding the lysis of HIV-1-infected cells by CTL are available. We studied the ability of HIV-1-s
Effect of human immunodeficiency virus type 1 protein R (vpr) gene expression on basic cellular function of fission yeast Schizosaccharomyces pombe.: J Virol. 1996 Sep;70(9):5821-6. Unique Identifier : AIDSLINE MED/96323093; Zhao Y; Cao J; O'Gorman MR; Yu M; Yogev R; Section of Pediatric and Maternal Human Immunodeficiency Virus; Infections, Children's Memorial Hospital, Illinois, USA.; yzhao@nwu.edu; The human immunodeficiency virus type 1 (HIV-1) Vpr protein affects cell morphology and prevents proliferation of human cells by induction of cell cycle G2 arrest. In this study, we used the fission yeast Schizosaccharomyces pombe as a model system to investigate the cellular effects of HIV-1 vpr gene expression. The
Conditional human immunodeficiency virus type 1 protease mutants show no role for the viral protease early in virus replication.: J Virol. 1996 Sep;70(9):5840-4. Unique Identifier : AIDSLINE MED/96323096; Kaplan AH; Manchester M; Smith T; Yang YL; Swanstrom R; Department of Medicine, University of California at Los Angeles; 90024, USA.; The human immunodeficiency virus type 1 protease plays a critical role in the proteolytic processing of precursor polyproteins during virion maturation. Contradictory evidence has been obtained for a possible role for the protease early after infection, i.e., during DNA synthesis and/or integration. We have reexamined
Requirements for kissing-loop-mediated dimerization of human immunodeficiency virus RNA.: J Virol. 1996 Sep;70(9):5902-8. Unique Identifier : AIDSLINE MED/96323104; Clever JL; Wong ML; Parslow TG; Department of Pathology, University of California, San Francisco; 94143, USA.; Sequences from the 5 end of type 1 human immunodeficiency virus RNA dimerize spontaneously in vitro in a reaction thought to mimic the initial step of genomic dimerization in vivo. Dimer initiation has been proposed to occur through a kissing-loop interaction involving a specific RNA stem-loop element designated SL1:
Directional budding of human immunodeficiency virus from monocytes.: J Virol. 1996 Sep;70(9):5916-21. Unique Identifier : AIDSLINE MED/96323106; Perotti ME; Tan X; Phillips DM; Department of General Physiology and Biochemistry, University of; Milan, Italy.; Time-lapse cinematography revealed that activated human immunodeficiency virus (HIV)-infected monocytes crawl along surfaces, putting forward a leading pseudopod. Scanning electron micrographs showed monocyte pseudopods associated with spherical structures the size of HIV virions, and transmission electron micrographs
Human immunodeficiency virus type 1 drug susceptibility during zidovudine (AZT) monotherapy compared with AZT plus 2',3'-dideoxyinosine or AZT plus 2',3'-dideoxycytidine combination therapy. The protocol 34,225-02 Collaborative Group.: J Virol. 1996 Sep;70(9):5922-9. Unique Identifier : AIDSLINE MED/96323107; Larder BA; Kohli A; Bloor S; Kemp SD; Harrigan PR; Schooley RT; Lange JM; Pennington KN; St. Clair MH; Glaxo Wellcome Research and Development, Stevenage,; Hertfordshire, United Kingdom.; Human immunodeficiency virus type 1 (HIV-1) isolates obtained prior to and during a combination therapy trial comparing zidovudine ( AZT ; 3 -azidothymidine) monotherapy with AZT plus 2 ,3 -dideoxyinosin
Significance of amino acid variation at human immunodeficiency virus type 1 reverse transcriptase residue 210 for zidovudine susceptibility.: J Virol. 1996 Sep;70(9):5930-4. Unique Identifier : AIDSLINE MED/96323108; Harrigan PR; Kinghorn I; Bloor S; Kemp SD; Najera I; Kohli A; Larder BA; Glaxo Wellcome Research and Development, Stevenage, United; Kingdom.; Amino acid variation at reverse transcriptase (RT) codon 210 (generally Leu-210 to Trp [L210W], TTG-->TGG) is occasionally detected after the initiation of azidothymidine ( AZT ) therapy. The impact of this variation on AZT resistance and viral replicat
Full-length sequence and mosaic structure of a human immunodeficiency virus type 1 isolate from Thailand.: J Virol. 1996 Sep;70(9):5935-43. Unique Identifier : AIDSLINE GENBANK/U54771; Carr JK; Salminen MO; Koch C; Gotte D; Artenstein AW; Hegerich PA; St Louis D; Burke DS; McCutchan FE; Henry M. Jackson Foundation for the Advancement of Military; Medicine, Rockville, Maryland 20850, USA. jcarr@hiv.hjf.org; Human immunodeficiency virus type 1 isolates of envelope genotype E are contributing substantially to the global pandemic. These strains appear to be mosaics, with the gag gene from clade A and the envelope from clade E; the parental clade E strain has not been found. Here we report the first full genomic sequence of
The posttranscriptional control element of the simian retrovirus type 1 forms an extensive RNA secondary structure necessary for its function.: J Virol. 1996 Sep;70(9):5998-6011. Unique Identifier : AIDSLINE MED/96323116; Tabernero C; Zolotukhin AS; Valentin A; Pavlakis GN; Felber BK; Human Retrovirus Pathogenesis Group, ABL-Basic Research Program,; National Cancer Institute-Frederick Cancer Research and; Development Center, Maryland 21702-1201, USA.; It was previously shown that a 240-nucleotide (nt) RNA element (cis-acting transactivation element [CTE]) located between the env gene and the 3 long terminal repeat of simian retrovirus type 1 (SRV-1) can functionally replace posttranscriptional activation directed by Rev and the Rev-responsive element (RRE) when in
Characterization of a 120-Kilodalton pre-S-binding protein as a candidate duck hepatitis B virus receptor.: J Virol. 1996 Sep;70(9):6029-35. Unique Identifier : AIDSLINE MED/96323119; Li JS; Tong SP; Wands JR; Molecular Hepatology Laboratory, Massachusetts General Hospital; Cancer Center, Charlestown, Massachusetts 02129, USA.; Infection by human and animal hepadnaviruses displays remarkable host and tissue tropism. The infection cycle probably initiates with binding of the pre-S domain of viral envelope protein to surface receptors present on the hepatocyte. Three types of neutralizing monoclonal antibodies against duck hepatitis B virus (D
Mutational analysis of the envelope protein of spleen necrosis virus.: J Virol. 1996 Sep;70(9):6036-43. Unique Identifier : AIDSLINE MED/96323120; Martinez I; Dornburg R; Graduate Program in Microbiology and Molecular Genetics, Rutgers; University, New Brunswick, New Jersey 08903, USA.; Spleen necrosis virus (SNV) is an amphotropic type C retrovirus originally isolated from a duck. The envelope protein is related to that of type D retroviruses, and SNV appears to use the same receptor as do simian retroviruses. However, little is known about envelope-receptor interactions of SNV. We constructed a ser
CD4 down-modulation during infection of human T cells with human immunodeficiency virus type 1 involves independent activities of vpu, env, and nef.: J Virol. 1996 Sep;70(9):6044-53. Unique Identifier : AIDSLINE MED/96323121; Chen BK; Gandhi RT; Baltimore D; Department of Biology, Massachusetts Institute of Technology,; Cambridge 02139, USA.; The human immunodeficiency virus type 1 (HIV-1) genes vpu, env, and nef have all been implicated in modulating the levels of cell surface CD4 on infected cells. To quantitatively assess the relative contribution of each gene product to the regulation of CD4 during HIV infection of Jurkat T cells and peripheral blood m
Characterization of human immunodeficiency virus type 1 Vif particle incorporation.: J Virol. 1996 Sep;70(9):6106-11. Unique Identifier : AIDSLINE MED/96323128; Camaur D; Trono D; Infectious Disease Laboratory, Salk Institute for Biological; Studies, La Jolla, California 92037, USA.; The human immunodeficiency virus type 1 (HIV-1) Vif protein is necessary at the time of viral particle formation yet functionally manifests its effect after virions enter target cells. This suggests that Vif either acts on another viral protein or is itself incorporated into particles. In this study, we have examined
Translation initiation in GB viruses A and C: evidence for internal ribosome entry and implications for genome organization.: J Virol. 1996 Sep;70(9):6126-35. Unique Identifier : AIDSLINE GENBANK/U22303; Simons JN; Desai SM; Schultz DE; Lemon SM; Mushahwar IK; Virus Discovery Group, Abbott Laboratories, North Chicago,; Illinois 60064-4000, USA. simonsj@apmac.abbott.com; GB viruses A and C (GBV-A and GBV-C) are two recently described RNA viruses which appear to be members of the Flaviviridae. Although both viruses appear to contain long 5 nontranslated regions, the sites of polyprotein initiation and the presence of core-like proteins remain to be determined. Translation studies were
Increased envelope spike density and stability are not required for the neutralization resistance of primary human immunodeficiency viruses.: J Virol. 1996 Sep;70(9):6136-42. Unique Identifier : AIDSLINE MED/96323132; Karlsson GB; Gao F; Robinson J; Hahn B; Sodroski J; Division of Human Retrovirology, Dana-Farber Cancer Institute,; Boston, Massachusetts, USA.; Previous observations that the gp120 envelope glycoprotein contents of some primary, clade B human immunodeficiency virus type 1 (HIV-1) isolates were higher than those of laboratory-passaged HIV-1 isolates suggested the hypothesis that increased envelope glycoprotein spike density or stability contributes to the rela
Amino acids essential for RNase H activity of hepadnaviruses are also required for efficient elongation of minus-strand viral DNA.: J Virol. 1996 Sep;70(9):6151-6. Unique Identifier : AIDSLINE MED/96323134; Chen Y; Marion PL; Division of Infectious Diseases and Geographic Medicine,; University School of Medicine, Stanford, California 94305, USA.; The hepadnavirus P gene contains amino acid sequences which share homology with all known RNases H. In this study, we made four mutants in which single amino acids of the duck hepatitis B virus (DHBV) RNase H region were altered. In two of them, amino acids at locations comprising the putative catalytic site were chan
Human immunodeficiency virus type 1 Nef associates with a member of the p21-activated kinase family.: J Virol. 1996 Sep;70(9):6157-61. Unique Identifier : AIDSLINE MED/96323135; Nunn MF; Marsh JW; Laboratory of Molecular Biology, National Institute of Mental; Health, Bethesda, Maryland 20892, USA.; Although human immunodeficiency virus (HIV) Nef is essential for the induction of AIDS, its biochemical function has remained an enigma. In this study, HIV Nef protein is shown to associate with a serine-threonine kinase that recognizes histone H4 as a substrate, is serologically related to rat p21-activated kinase (P
Inhibitors of human immunodeficiency virus type 1 zinc fingers prevent normal processing of gag precursors and result in the release of noninfectious virus particles.: J Virol. 1996 Sep;70(9):6180-9. Unique Identifier : AIDSLINE MED/96323138; Turpin JA; Terpening SJ; Schaeffer CA; Yu G; Glover CJ; Felsted RL; Sausville EA; Rice WG; Laboratory of Antiviral Drug Mechanisms, National Cancer; Institute-Frederick Cancer Research and Development Center, SAIC; Frederick, Maryland 21702, USA.; The Cys-Xaa2-Cys-Xaa4-His-Xaa4-Cys zinc fingers of retroviral nucleocapsid proteins are prime antiviral targets because of conservation of the Cys and His chelating residues and the absolute requirement of these fingers in both early and late phases of retroviral replication. We previously reported that certain disulf
A longitudinal study of feline immunodeficiency virus-specific cytotoxic T lymphocytes in experimentally infected cats, using antigen-specific induction.: J Virol. 1996 Sep;70(9):6199-206. Unique Identifier : AIDSLINE MED/96323140; Beatty JA; Willett BJ; Gault EA; Jarrett O; Department of Veterinary Pathology, University of Glasgow,; Bearsden, United Kingdom.; The evolution of the virus-specific cytotoxic T-lymphocyte response in two cats experimentally infected with feline immunodeficiency virus (FIV) was monitored. Effector cells were derived from peripheral blood lymphocytes during the acute and chronic phases of infection (0 to 21 and 62 to 127 weeks, respectively) and
Multivariate analysis of human immunodeficiency virus type 1 neutralization data.: J Virol. 1996 Sep;70(9):6235-43. Unique Identifier : AIDSLINE MED/96323144; Nyambi PN; Nkengasong J; Lewi P; Andries K; Janssens W; Fransen K; Heyndrickx L; Piot P; van der Groen G; Institute of Tropical Medicine, Antwerp, Belgium.; We report on the use of spectral map analysis of the inter- and intraclade neutralization data of 14 sera of human immunodeficiency virus type 1 (HIV-1)-infected individuals and 16 primary isolates, representing genetic clades A to H in group M and group O. This multivariate analysis has been used previously to study
A seven-transmembrane domain receptor involved in fusion and entry of T-cell-tropic human immunodeficiency virus type 1 strains.: J Virol. 1996 Sep;70(9):6288-95. Unique Identifier : AIDSLINE MED/96323150; Berson JF; Long D; Doranz BJ; Rucker J; Jirik FR; Doms RW; Department of Pathology and Laboratory Medicine, University of; Pennsylvania, Philadelphia 19104, USA.; Entry of human immunodeficiency virus type 1 (HIV-1) into cells requires binding to CD4 and fusion with a cellular membrane. Fusion does not occur in most nonhuman cells even when they express human CD4, indicating that one or more human accessory factors are required for virus infection. Recently, a seven-transmembra
Peripheral blood mononuclear cells from sheep infected with a variant of bovine leukemia virus synthesize envelope glycoproteins but fail to induce syncytia in culture.: J Virol. 1996 Sep;70(9):6296-303. Unique Identifier : AIDSLINE MED/96323151; Johnston ER; Powers MA; Kidd LC; Radke K; Department of Avian Sciences, University of California, Davis; 95616-8532, USA.; Peripheral blood mononuclear cells (PBMCs) infected with the oncogenic retrovirus bovine leukemia virus (BLV) produce virus when cultured briefly. BLV can be transmitted in cocultures to adherent susceptible cells, which become infected, express viral proteins, and fuse into multinucleated syncytia several days later.
Localization of human T-cell leukemia virus type 1 tax to subnuclear compartments that overlap with interchromatin speckles.: J Virol. 1996 Sep;70(9):6347-57. Unique Identifier : AIDSLINE MED/96323157; Semmes OJ; Jeang KT; Molecular Virology Section, National Institute of Allergy and; Infectious Disease, Bethesda, Maryland 20892, USA.; Tax, the virally encoded activator of the human T-cell leukemia virus type 1 long terminal repeats, regulates the expression of many cellular genes. This protein has been implicated in transformation events leading to the development of adult T-cell leukemia. Because subcellular localization contributes importantly to
Identification of domains in the simian immunodeficiency virus matrix protein essential for assembly and envelope glycoprotein incorporation.: J Virol. 1996 Sep;70(9):6384-9. Unique Identifier : AIDSLINE MED/96323161; Gonzalez SA; Burny A; Affranchino JL; Centro de Virologia Animal, Buenos Aires, Argentina.; sag@cevan.sld.ar; The matrix domain (MA) of the simian immunodeficiency virus (SIV) is encoded by the amino-terminal region of the Gag polyprotein precursor and is the component of the viral capsid that lines the inner surface of the virus envelope. To define domains of the SIV MA protein that are involved in virus morphogenesis, delet
Possible origin of murine AIDS (MAIDS) virus: conversion of an endogenous retroviral p12gag sequence to a MAIDS-inducing sequence by frameshift mutations.: J Virol. 1996 Sep;70(9):6405-9. Unique Identifier : AIDSLINE MED/96323165; Kubo Y; Kakimi K; Higo K; Kobayashi H; Ono T; Iwama Y; Kuribayashi K; Hiai H; Adachi A; Ishimoto A; Department of Viral Oncology, Institute for Virus Research,; Kyoto, Japan.; The murine AIDS (MAIDS) virus has a unique sequence in its p12gag region, which is responsible for MAIDS development. A transcript hybridizing with this sequence is expressed in normal C57BL/6 mice. The transcript, designated Edv, has been previously cloned and sequenced (Y. Kubo, Y. Nakagawa, K. Kakimi, H. Matsui, K.
Differential glycosylation, virion incorporation, and sensitivity to neutralizing antibodies of human immunodeficiency virus type 1 envelope produced from infected primary T-lymphocyte and macrophage cultures.: J Virol. 1996 Sep;70(9):6431-6. Unique Identifier : AIDSLINE MED/96323170; Willey RL; Shibata R; Freed EO; Cho MW; Martin MA; Laboratory of Molecular Microbiology, National Institute of; Allergy and Infectious Diseases, Bethesda, Maryland 20892, USA.; Two primary cell targets for human immunodeficiency virus type 1 (HIV-1) infection in vivo are CD4+ T lymphocytes and monocyte-derived macrophages (MDM). HIV-1 encodes envelope glycoproteins which mediate virus entry into these cells. We have utilized infected and radiolabelled primary peripheral blood mononuclear cel
Human immunodeficiency virus type 1 membrane fusion mediated by a laboratory-adapted strain and a primary isolate analyzed by resonance energy transfer.: J Virol. 1996 Sep;70(9):6437-41. Unique Identifier : AIDSLINE MED/96323171; Litwin V; Nagashima KA; Ryder AM; Chang CH; Carver JM; Olson WC; Alizon M; Hasel KW; Maddon PJ; Allaway GP; Progenics Pharmaceuticals, Inc., Tarrytown, New York 10591, USA.; Previous studies of human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein-mediated membrane fusion have focused on laboratory-adapted T-lymphotropic strains of the virus. The goal of this study was to characterize membrane fusion mediated by a primary HIV-1 isolate in comparison with a laboratory-adapted s
The human T-cell leukemia virus type 1 posttranscriptional trans-activator Rex contains a nuclear export signal.: J Virol. 1996 Sep;70(9):6442-5. Unique Identifier : AIDSLINE MED/96323172; Palmeri D; Malim MH; Graduate Group in Molecular Biology, University of Pennsylvania; School of Medicine, Philadelphia 19104-6148, USA.; The Rex protein of human T-cell leukemia virus type 1 is required for the nuclear export of unspliced viral mRNA and, therefore, for virus replication. In this manuscript, we demonstrate that Rex shuttles between the nucleus and the cytoplasm and that its activation domain constitutes a nuclear export signal that spec
Genetics of intracisternal-A-particle-related envelope-encoding proviral elements in mice.: J Virol. 1996 Sep;70(9):6450-4. Unique Identifier : AIDSLINE MED/96323174; Reuss FU; Frankel WN; Moriwaki K; Shiroishi T; Coffin JM; Department of Molecular Biology and Microbiology, Tufts; University School of Medicine, Boston, Massachusetts 02111, USA.; Intracisternal-A-particle-related envelope-encoding (IAPE) proviral elements in the mouse genome encode and express an envelope-like protein that may allow transmission of IAPEs as infectious agents. To test IAPE mobility and potential transmission in mice, we have analyzed the distribution of IAPE elements in the gen
Relationship between viral DNA synthesis and virion envelopment in hepatitis B viruses.: J Virol. 1996 Sep;70(9):6455-8. Unique Identifier : AIDSLINE MED/96323175; Wei Y; Tavis JE; Ganem D; Howard Hughes Medical Institute, University of California Medical; Center, San Francisco 94143, USA.; While the intracellular pool of encapsidated hepatitis B viral DNA contains genomes in all stages of DNA replication, serum-derived virions contain predominantly mature, partially duplex, circular DNA genomes. To account for this finding, Summers and Mason proposed in 1982 that virion envelopment is somehow linked to
Sequence analysis of the human DNA flanking sites of human immunodeficiency virus type 1 integration.: J Virol. 1996 Sep;70(9):6459-62. Unique Identifier : AIDSLINE GENBANK/H11552; Stevens SW; Griffith JD; Department of Microbiology and Immunology, University of North; Carolina at Chapel Hill 27599-7295, USA.; Human immunodeficiency virus type 1 (HIV-1) tagged with the Escherichia coli supF gene has been used to clone integrated HIV-1 proviruses. Sequence analysis of the 600 to 800 bp of human DNA adjacent to 29 clones revealed a propensity for HIV-1 to integrate near the Alu class of human repetitive elements.
The association of Nef with a cellular serine/threonine kinase and its enhancement of infectivity are viral isolate dependent.: J Virol. 1996 Sep;70(9):6493-6. Unique Identifier : AIDSLINE MED/96323182; Luo T; Garcia JV; Department of Virology and Molecular Biology, St. Jude Children's; Research Hospital, Memphis, Tennessee 38101, USA.; The nef genes of human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus (SIV) encode a 27- to 34-kDa myristoylated protein which induces downregulation of CD4 surface levels and enhances virus infectivity. In adult macaques, Nef has been implicated in pathogenesis and disease progression. Both H
Resistance of chimpanzee T cells to human immunodeficiency virus type 1 Tat-enhanced oxidative stress and apoptosis.: J Virol. 1996 Sep;70(9):6502-7. Unique Identifier : AIDSLINE MED/96323184; Ehret A; Westendorp MO; Herr I; Debatin KM; Heeney JL; Frank R; Krammer PH; Tumor Immunology Program, German Cancer Research Center,; Heidelberg, Germany.; CD4+ T-cell depletion in AIDS patients involves induction of apoptosis in human immunodeficiency virus (HIV)-infected and noninfected T cells. The HIV type 1 (HIV-1)-transactivating protein Tat enhances apoptosis and activation-induced cell death (AICD) of human T cells. This effect is mediated by the CD95 (APO-1/Fas)
Identification of HIV-1 group O infection--1996. From the Centers for Disease Control and Prevention.: JAMA. 1996 Aug 21;276(7):521-2. Unique Identifier : AIDSLINE MED/96345579
Perinatal HIV infection [letter; comment]: JAMA. 1996 Aug 21;276(7):527-8. Unique Identifier : AIDSLINE MED/96345584; Cohn SE; Klein JD
HTLV-I infections in offspring derived from HTLV-I carrier rats during the suckling period.: Kurume Med J. 1996;43(1):1-9. Unique Identifier : AIDSLINE MED/96261714; Ohsugi T; Urano T; Masunaga K; Shingu M; Department of Virology, Kurume University School of Medicine,; Japan.; An experimental rat model for vertical transmission of human T cell leukemia virus type I (HTLV-I) was used to examine whether the infection of offspring derived from HTLV-I carrier rats could be established during the suckling period. MT-2 (2 x 10(7)) cells were injected into 5-week-old rats twice, at 2-week interval
Making the difference.: Ky Nurse. 1996 Jan-Mar;44(1):25. Unique Identifier : AIDSLINE MED/96345412; Newman K
Controlling infantile AIDS with natural remedies--a Romanian case study.: J Tradit Chin Med. 1995 Dec;15(4):277-88. Unique Identifier : AIDSLINE MED/96329863; Tani M; Tani Clinic, Tokyo, Japan.
Human acute myeloid leukemias may be etiologically associated with new human retroviral infection [see comments]: Leuk Res. 1996 Jun;20(6):449-55. Unique Identifier : AIDSLINE MED/96319755; Xu R; Gao Q; Wang S; Kan H; Sheng L; Li C; Zhang X; Xu G; Zhang K; Hematology Research Division, Department of Medicine, 2nd; Affiliated Hospital, Zhejiang Medical University, Hangzhou,; People's Republic of China.; The etiology of human acute myeloid leukemias (AML) remains uncertain. In order to examine the possibility of retroviral etiology in AML, we determined retroviral antigens related to HTLV-I in leukemic cell samples from 32 AML cases and peripheral blood mononuclear cells (PBMNCs) from 20 healthy donors by D-IGSS with
HTLV infection and hematologic malignancies [comment]: Leuk Res. 1996 Jun;20(6):457-8. Unique Identifier : AIDSLINE MED/96319756; Loughran TP; Veterans Administration Medical Center, Syracuse, NY 13210, USA.
Detection of HHV-8/KSHV DNA sequences in AIDS-associated extranodal lymphoid malignancies.: Leukemia. 1996 Aug;10(8):1358-62. Unique Identifier : AIDSLINE MED/96320611; Otsuki T; Kumar S; Ensoli B; Kingma DW; Yano T; Stetler-Stevenson M; Jaffe ES; Raffeld M; Laboratory of Pathology, National Cancer Institute, National; Institutes of Health, Bethesda, MD, USA.; Herpesvirus-like DNA sequences have been identified in a high proportion of both AIDS-associated and classical Kaposi s sarcoma, and in a small percentage of AIDS-associated malignant lymphomas. To determine the extent of involvement of this new agent designated HHV-8 (human herpesvirus type 8) or KSHV (Kaposi s sarco
HTLV-I-associated adult T cell leukemia/lymphoma in two patients from Bucharest, Romania.: Leukemia. 1996 Aug;10(8):1366-9. Unique Identifier : AIDSLINE MED/96320614; Veelken H; Kohler G; Schneider J; Dierbach H; Mertelsmann R; Schaefer HE; Lubbert M; Department of Internal Medicine I (Hematology/Oncology), Freiburg; University Medical Center, Germany.; Two middle-aged patients with T cell lymphoma, both natives of Bucharest, Romania , tested positive for HTLV-I antibodies. Malignant cells had the typical phenotype and morphology of adult T cell leukemia/lymphoma (ATL). Both cases presented with extranodal manifestation, hypercalc
Delta in the real world [comment]: Lancet. 1996 Aug 3;348(9023):278-9. Unique Identifier : AIDSLINE MED/96312255; Sherer R; HIV Primary Care Center, Cook County Hospital, Chicago, Illinois; 60612, USA.
Delta: a randomised double-blind controlled trial comparing combinations of zidovudine plus didanosine or zalcitabine with zidovudine alone in HIV-infected individuals. Delta Coordinating Committee [see comments]: Lancet. 1996 Aug 3;348(9023):283-91. Unique Identifier : AIDSLINE MED/96312260; BACKGROUND: Because the benefits of zidovudine ( AZT ) in HIV-infected individuals are small and do not last long the Delta trial was designed to test whether combinations of zidovudine with didanosine (ddl) or zalcitabine (
HIV-associated respiratory diseases.: Lancet. 1996 Aug 3;348(9023):307-12. Unique Identifier : AIDSLINE MED/96312265; Miller R; Department of Sexually Transmitted Diseases, University College; London Medical School, UK.; The lungs of individuals infected with HIV are often affected by opportunistic infections and tumours; over two-thirds of patients have at least one respiratory episode during the course of their disease. Despite the availability of effective prophylaxis, infection with the fungus Pneumocystis carinii remains a common
Montreal needle-exchange surprise [news]: Lancet. 1996 Aug 3;348(9023):324. Unique Identifier : AIDSLINE MED/96312268
US specialists object to AMA's call for mandatory HIV testing [news]: Lancet. 1996 Aug 3;348(9023):330. Unique Identifier : AIDSLINE MED/96312270; Rovner J
Gastrointestinal manifestations of HIV infection.: Lancet. 1996 Aug 10;348(9024):379-83. Unique Identifier : AIDSLINE MED/96322233; Sharpstone D; Gazzard B; Department of HIV/GUM, Kobler Centre, Cheslea and Westminster; Hospital, London, UK.; The harrowing picture of emaciated terminally ill AIDS patients is a reminder of our lack of understanding of immunological mechanisms that normally control opportunistic infections. Many gastrointestinal pathogens in patients with AIDS are resistant to treatment and lead inexorably to weight loss and death. Although
Active tuberculosis boosts HIV replication [news]: Lancet. 1996 Aug 10;348(9024):393. Unique Identifier : AIDSLINE MED/96322236; McCarthy M
HIV epidemic in India [letter]: Lancet. 1996 Aug 10;348(9024):412-3. Unique Identifier : AIDSLINE MED/96322257; Jain M; John TJ
Measles case fatality by sex, vaccination status, and HIV-1 antibody in Zambian children [letter]: Lancet. 1996 Aug 10;348(9024):415. Unique Identifier : AIDSLINE MED/96322263; Oshitani H; Suzuki H; Mpabalwani ME; Mizuta K; Numazaki Y
Neurological complications of HIV infection.: Lancet. 1996 Aug 17;348(9025):445-52. Unique Identifier : AIDSLINE MED/96332172; Price RW; Department of Neurology, San Francisco General Hospital, CA; 94110-3518, USA.; Neurological complications of HIV infection cause considerable morbidity and are often associated with high mortality. These complications include not only the more common opportunistic diseases affecting the brain (cerebral toxoplasmosis, primary central nervous system lymphoma, progressive multifocal leucoencephalop
HIV-1-resistant individuals may lack HIV-1 coreceptor [news]: Lancet. 1996 Aug 17;348(9025):463. Unique Identifier : AIDSLINE MED/96332177; Bradbury J
'Chicane-like' airway as a complication of lingual tonsils [letter]: Lancet. 1996 Aug 17;348(9025):475. Unique Identifier : AIDSLINE MED/96332186; Conacher ID; McMahon CC; Meikle D
Outpatients care of HIV-1-infected destitute people: a study in Paris, France [letter]: Lancet. 1996 Aug 17;348(9025):480. Unique Identifier : AIDSLINE MED/96332197; Chauvin P; Mortier E; Valleron AJ; Lebas J
Global burden of the HIV epidemic [letter]: Lancet. 1996 Aug 17;348(9025):480-1. Unique Identifier : AIDSLINE MED/96332198; Stewart GT
Relationship of HIV-1 envelope V2 and V3 sequences of the primary isolates to the viral phenotype.: Microbiol Immunol. 1996;40(4):277-87. Unique Identifier : AIDSLINE MED/96336198; Yoshimura K; Matsushita S; Hayashi A; Takatsuki K; Second Department of Internal Medicine, Kumamoto University; School of Medicine, Japan.; We examined the relationship between the amino acid sequences of the V2 and V3 regions of the envelope protein and the biological properties of ten human immunodeficiency virus type 1 (HIV-1) primary isolates. The infectivity, cytopathic effect (CPE), and syncytium forming activity of these primary isolates were teste
HIV and complementary medicine.: Med J Aust. 1996 Aug 5;165(3):143-5. Unique Identifier : AIDSLINE MED/96339396; McKnight I; Scott M; Australian Federation of AIDS Organisations, Sydney, NSW.; Many people with HIV use complementary or alternative therapies, often without the knowledge of their doctors. To encourage open communication with their patients, doctors need to be aware of what complementary therapies are available and willing to discuss their use. They are then in a better position to defend their
HIV and choosing to die.: Med J Aust. 1996 Aug 5;165(3):146. Unique Identifier : AIDSLINE MED/96339397; van Reyk P; People with HIV have been encouraged to take control of their health and the monitoring and treatment of their illnesses. Many claim the right to choose the time and manner of death.
Legal issues in HIV medicine.: Med J Aust. 1996 Aug 5;165(3):147-9. Unique Identifier : AIDSLINE MED/96339398; Chapman S; The mortality, stigma and publicity surrounding HIV/AIDS have brought into focus many legal and ethical issues arising in the practice of medicine. Three important aspects of the practice of HIV medicine are the obligation to notify health authorities of HIV diagnoses, special obligations to inform and counsel patient
HIV care: the impact on the doctor.: Med J Aust. 1996 Aug 5;165(3):150. Unique Identifier : AIDSLINE MED/96339399; Kelly BJ; Todhunter L; Raphael B; University of Queensland, Brisbane.; Managing patients with HIV raises complex clinical, ethical and personal challenges. Burnout threatens the overcommitted doctor who is not prepared to take preventive measures.
Continuing HIV education for health care workers.: Med J Aust. 1996 Aug 5;165(3):151-2. Unique Identifier : AIDSLINE MED/96339400; Stewart GJ; Bollen MD; Van Der Weyden MB; Department of Clinical Immunology and Allergy, Westmead Hospital,; Sydney, NSW.; A five-year national education program for HIV/AIDS has brought into focus many issues in continuing education and has evolved models worthy of consideration by colleagues in other fields.
[Attitude of established physicians to treating HIV-infected patients and to acquired immunodeficiency syndrome. An empirical study]: Med Klin. 1996 May 15;91(5):272-6. Unique Identifier : AIDSLINE MED/96261743; Loew TH; Heerwagen E; Abteilung fur Psychosomatische Medizin und Psychotherapie,; Universitat Erlangen-Nurnberg.; BACKGROUND: There is no empirical data available on attitudes concerning AIDS and habits towards HIV infected patients of physicians in general or private practice. In this study results of a self-evaluation are presented. METHODS: 178 physicians working with out-patients in different medical fields were randomly sele
The ethical dilemmas of mandatory prenatal and newborn HIV testing.: Nursingconnections. 1995 Winter;8(4):43-50. Unique Identifier : AIDSLINE MED/96337063; Downes J
Uveitis during treatment of disseminated Mycobacterium avium-intracellulare complex infection with the combination of rifabutin, clarithromycin and ethambutol.: Neth J Med. 1996 Jun;48(6):211-5. Unique Identifier : AIDSLINE MED/96300965; Lowe SH; Kroon FP; Bollemeyer JG; Stricker BH; van 't Wout JW; Department of Infectious Diseases, University Hospital Leiden,; Netherlands.; Three patients with a cellular immunodeficiency were treated with rifabutin, clarithromycin and ethambutol for a disseminated infection with Mycobacterium avium-intracellulare complex (MAC). The patients developed uveitis, sometimes in combination with a transient rash, arthralgia, arthritis, jaundice and pseudojaundi
Subacute leukoencephalitis caused by CNS infection with human herpesvirus-6 manifesting as acute multiple sclerosis.: Neurology. 1996 Jul;47(1):145-8. Unique Identifier : AIDSLINE MED/96291032; Carrigan DR; Harrington D; Knox KK; Department of Pathology, Medical College of Wisconsin, Milwaukee; 53226, USA.; Several recent reports have documented the neuroinvasiveness of human herpesvirus-6 (HHV-6) in infants with primary HHV-6 infections, in children and adults with AIDS, in recipients of bone marrow transplants, and in immunologically intact adults and children. CNS infections with HHV-6 can be subacute and are frequent
National health policy: lessons from a hot seat.: Nurs Adm Q. 1996 Spring;20(3):9-18. Unique Identifier : AIDSLINE MED/96339683; Gebbie KM; The author served as the nation s acquired immune deficiency syndrome (AIDS) policy coordinator from August 1993 to July 1994. Given the background of conflict surrounding human immunodeficiency virus (HIV) and AIDS policy in the United States , conflict about the position and function
The HIV antibody test.: Nurse Pract. 1996 Mar;21(3):121-2. Unique Identifier : AIDSLINE MED/96247859
Infectious mononucleosis.: Nurse Pract. 1996 Mar;21(3):14-6, 23, 27-8. Unique Identifier : AIDSLINE MED/96247851; Cozad J; Huntington Beach Community Clinic, Calif., USA.; Infectious mononucleosis is an acute, self-limiting, nonneoplastic lymphoreticular proliferative disorder characterized by peripheral lymphocytosis and circulating atypical lymphocytes. Epstein-Barr virus is the causative agent in 90% of cases. Highest incidence is in the 15- to 25-year-old age-group, with 1% to 3% of
New drugs.: Nursing. 1996 May;26(5):52-6. Unique Identifier : AIDSLINE MED/96345027; Hussar DA
AIDS projections [news]: Occup Health (Lond). 1996 Jan;48(1):4. Unique Identifier : AIDSLINE MED/96345502
Mechanisms of transcriptional transactivation and restriction of human immunodeficiency virus type I replication in an astrocytic glial cell.: Oncogene. 1996 Jul 18;13(2):313-22. Unique Identifier : AIDSLINE MED/96313266; Niikura M; Dornadula G; Zhang H; Mukhtar M; Lingxun D; Khalili K; Bagasra O; Pomerantz RJ; Dorrance H Hamilton Laboratories, Department of Medicine,; Jefferson Medical College, Thomas Jefferson University,; Philadelphia, Pennsylvania 19107, USA.; Unique transcriptional transactivation by the human immunodeficiency virus type 1 (HIV-1) Tat protein of long terminal repeat (LTR)-driven RNA expression, in the absence of the transactivator responsive element (TAR), was previously demonstrated in central nervous system (CNS)-derived astrocytic cell-lines, including
Characterization of several kinds of dimer minizyme: simultaneous cleavage at two sites in HIV-1 tat mRNA by dimer minizymes.: Nucleic Acids Res. 1996 Jun 15;24(12):2302-10. Unique Identifier : AIDSLINE MED/96279730; Kuwabara T; Amontov SV; Warashina M; Ohkawa J; Taira K; National Institute of Bioscience and Human Technology, Agency of; Industrial Science and Technology, MITI, Tsukuba Science City,; Japan.; A minizyme is a hammerhead ribozyme with short oligonucleotide linkers instead of stem-loop II. In a previous study we demonstrated that a minizyme with high activity forms a dimeric structure with a common stem II. Because of their dimeric structure, minizymes are potentially capable of cleaving a substrate at two di
Safe sex advice for mental health patients [news]: Nurs Times. 1996 Mar 20-26;92(12):14. Unique Identifier : AIDSLINE MED/96339970; Kelly J; Murphy D; Bahr G
Old diseases die hard [news]: Nurs Times. 1996 Mar 20-26;92(12):18. Unique Identifier : AIDSLINE MED/96339972; Day M
Delegates protest at 'malicious' cuts in HIV funding [news]: Nurs Times. 1996 May 8-14;92(19):6. Unique Identifier : AIDSLINE MED/96345488
International perspectives. The unseen menace.: Nurs Times. 1996 Feb 21-27;92(8):50-1. Unique Identifier : AIDSLINE MED/96334561; Cassidy J
Women and social development.: Nurs J India. 1995 May;86(5):101-2. Unique Identifier : AIDSLINE MED/96334515
Revised pediatric HIV classification system.: Pediatr Dent. 1996 Mar-Apr;18(2):104-5. Unique Identifier : AIDSLINE MED/96265338
Pediatric HIV infection and its oral manifestations: a review.: Pediatr Dent. 1996 Mar-Apr;18(2):106-13. Unique Identifier : AIDSLINE MED/96265339; Chigurupati R; Raghavan SS; Studen-Pavlovich DA; Columbia University, New York, New York, USA.
Oral findings in asymptomatic (P-1) and symptomatic (P-2) HIV infected children.: Pediatr Dent. 1996 Mar-Apr;18(2):114-6. Unique Identifier : AIDSLINE MED/96265340; Del Toro A; Berkowitz R; Meyerowitz C; Frenkel LM; Eastman Dental Center, University of Rochester Medical Center,; USA.
Oral soft tissue manifestations and CD4 lymphocyte counts in HIV-infected children.: Pediatr Dent. 1996 Mar-Apr;18(2):117-20. Unique Identifier : AIDSLINE MED/96265341; Howell RB; Jandinski JJ; Palumbo P; Shey Z; Houpt MI; Department of Oral Pathology, Biology and Diagnostic Sciences,; New Jersey Dental School, USA.; This study investigated the prevalence of oral soft tissue lesions in children infected with HIV and the relationship of CD4 lymphocyte levels with the prevalence of those lesions. Sixty HIV-positive children enrolled in the Children s Hospital AIDS Program (age 5.8 +/- 3 years) were selected for study. Only five subj
Risk factors for HIV-related orofacial soft-tissue manifestations in children.: Pediatr Dent. 1996 Mar-Apr;18(2):121-6. Unique Identifier : AIDSLINE MED/96265342; Ramos-Gomez FJ; Hilton JF; Canchola AJ; Greenspan D; Greenspan JS; Maldonado YA; Department of Growth and Development, University of; California-San Francisco, USA.; A retrospective review of the medical records of 492 children perinatally exposed to the human immunodeficiency virus (HIV) compared the prevalence of orofacial soft-tissue manifestations in HIV-infected and noninfected children, identified risk factors for occurrence of orofacial lesions in HIV-infected children, and
Cancer in the HIV-infected child.: Pediatr Dent. 1996 Mar-Apr;18(2):127-8. Unique Identifier : AIDSLINE MED/96265343; Berkowitz R; Frenkel LM; Pediatrics Program, Eastman Dental Center, University of; Rochester Medical Center, USA.
Caries experience and cariogenic markers in HIV-positive children and their siblings.: Pediatr Dent. 1996 Mar-Apr;18(2):129-36. Unique Identifier : AIDSLINE MED/96265344; Madigan A; Murray PA; Houpt M; Catalanotto F; Feuerman M; Graduate School of Biomedical Sciences, University of Medicine; and Dentistry of New Jersey, USA.; The purpose of this cross-sectional, masked study was to compare the oral status of perinatally HIV-infected children with their uninfected siblings living in the same environment. A secondary purpose was to compare HIV-positive children for differences in oral health with respect to disease advancement. One hundred f
Compliance is poor among HIV-infected children with unmet dental needs.: Pediatr Dent. 1996 Mar-Apr;18(2):137-8. Unique Identifier : AIDSLINE MED/96265345; Broder HL; Catalanotto FA; Reisine S; Variagiannis E; Department of General and Hospital Dentistry, New Jersey Dental; School, Newark, USA.
Pharmacokinetic interaction between intravenous 2',3'-dideoxyinosine and pentamidine in rats.: Pharm Res. 1996 Apr;13(4):628-32. Unique Identifier : AIDSLINE MED/96267511; Yeh TK; Kang HJ; Wientjes MG; Au JL; Division of Pharmaceutics and Pharmaceutical Chemistry, Ohio; State University, Columbus 43210, USA.; PURPOSE. This study examined the pharmacokinetic interaction between 2 ,3 -dideoxyinosine (ddI) and pentamidine. BACKGROUND. ddI and pentamidine are often coadministered to patients with acquired immunodeficiency syndrome, and are both associated with pancreatic toxicity. Information on potential interaction would be
Long-term dual perfusion of isolated human placental lobules with improved oxygenation for infectious diseases research.: Placenta. 1996 Jan;17(1):57-68. Unique Identifier : AIDSLINE MED/96293548; Polliotti BM; Holmes R; Cornish JD; Hulsey M; Keesling S; Schwartz D; Abramowsky CR; Huddleston J; Panigel M; Nahmias AJ; Department of Pediatrics, Emory University School of Medicine,; Atlanta, Georgia, USA.; An improved method for long-term perfusion of the isolated human term placental lobule has been developed to investigate the maternofetal transfer of infectious agents, in particular the human immunodeficiency virus (HIV). The purpose of this paper is to describe those modifications that allow for substantially prolon
A three-hybrid system to detect RNA-protein interactions in vivo.: Proc Natl Acad Sci U S A. 1996 Aug 6;93(16):8496-501. Unique Identifier : AIDSLINE MED/96323251; SenGupta DJ; Zhang B; Kraemer B; Pochart P; Fields S; Wickens M; Department of Molecular Genetics and Microbiology, State; University of New York, Stony Brook 11794, USA.; RNA-protein interactions are pivotal in fundamental cellular processes such as translation, mRNA processing, early development, and infection by RNA viruses. However, in spite of the central importance of these interactions, few approaches are available to analyze them rapidly in vivo. We describe a yeast genetic meth
Induction of cytotoxic T lymphocytes by intramuscular immunization with plasmid DNA is facilitated by bone marrow-derived cells.: Proc Natl Acad Sci U S A. 1996 Aug 6;93(16):8578-83. Unique Identifier : AIDSLINE MED/96323266; Doe B; Selby M; Barnett S; Baenziger J; Walker CM; Chiron Corporation, Emeryville, CA 94608, USA.; Striated muscle is the predominant site of gene expression after i.m. immunization of plasmid DNA, but it is not clear if myocytes or professional antigen-presenting cells (APCs) of hematopoietic origin present the encoded antigens to class I major histocompatibility complex (MHC)-restricted cytotoxic T lymphocytes (C
Preventing perinatal transmission of HIV--costs and effectiveness of a recommended intervention.: Public Health Rep. 1996 Jul-Aug;111(4):335-41. Unique Identifier : AIDSLINE MED/96319583; Gorsky RD; Farnham PG; Straus WL; Caldwell B; Holtgrave DR; Simonds RJ; Rogers MF; Guinan ME; Department of Health Management and Policy, University of New; Hampshire, USA.; OBJECTIVE. To calculate the national costs of reducing perinatal transmission of human immunodeficiency virus through counseling and voluntary testing of pregnant women and zidovudine treatment of infected women and their infants, as recommended by the Public Health Service, and to compare these costs with the savings
Lesbian and bisexual women in small cities--at risk for HIV? HIV Prevention Community Collaborative.: Public Health Rep. 1996 Jul-Aug;111(4):347-52. Unique Identifier : AIDSLINE MED/96319585; Norman AD; Perry MJ; Stevenson LY; Kelly JA; Roffman RA; Innovative Programs Research Group, School of Social Work,; University of Washington, Seattle 98195, USA.; duecy@u.washington.edu
[AIDS and HIV infections in 1994]: Przegl Epidemiol. 1996;50(1-2):205-12. Unique Identifier : AIDSLINE MED/96309324; Szata W
[Cotrimoxazole induced dermatitis and curative treatment of AIDS pneumocystosis]: Rev Mal Respir. 1996;13(2):101-6. Unique Identifier : AIDSLINE MED/96272057; Caumes E; Service des Maladies Infectieuses et Tropicales, Hopital; Pitie-Salpetriere, Paris.; Adverse cutaneous reactions frequently occur during the treatment of AIDS associated pneumocystosis by trimethoprime-sulfamethoxazole. The most common form is a maculous rash. Treating throughout the duration of hypersensitivity may lead to potentially lethal Stevens-Johnson and Lyell syndromes. Slow acetylator phenot
Prognostic value of some laboratory parameters in a group of intravenous drug users in the early stages of HIV infection.: Recenti Prog Med. 1996 Jan;87(1):16-22. Unique Identifier : AIDSLINE MED/96308160; Cirasino L; Caroli A; Imbriani M; Prete A; Ferrario A; Silvani A; Divisione Medica Rizzi, Ospedale Niguarda Ca' Granda, Milano.; During a 5 year follow-up we found significantly reduced survival for non-accidental deaths in 37 intravenous drug users (IVUDs) in the early stages of HIV infection when compared with 32 HIV-negative IVUDs (p = 0.017). Moreover, in HIV-positive subjects, survival was significantly reduced for those groups which at th
Differential effect of the activation of protein kinase A on the protein synthesis and secretion in the T-helper 2 cell line D10.G4.1.: Scand J Immunol. 1996 Aug;44(2):150-6. Unique Identifier : AIDSLINE MED/96332612; Teschendorf C; Trenn G; Hoffkes HG; Brittinger G; Department of Internal Medicine, University of Essen, Germany.; The authors analysed the effect of protein kinase A (PKA) activation on the protein synthesis and secretion in the T-helper 2 cell line D10.G4.1 (D10) using an assay that allows the detection of almost all secreted proteins of a cell. IL-4 and IL-10 were quantified. Three groups of secretory products could be defined.
Genetic influence on the shaping of the human T-cell receptor repertoire: quantitative assessment by competitive polymerase chain reaction.: Scand J Immunol. 1996 Aug;44(2):173-8. Unique Identifier : AIDSLINE MED/96332615; Uhrberg M; Wernet P; Bone Marrow Donor Center, Heinrich-Heine University, Dusseldorf,; Germany.; It has been difficult to define the different factors which contribute to the shaping of the human T-cell receptor (TCR) repertoire. In this study, the influence of the polymorphic human leucocyte antigen (HLA) genes and non-HLA genes on the phenotype of the TCRBV segment repertoire was assessed in a population of HLA
[Tuberculosis in Switzerland in 1996: prevention and treatment]: Schweiz Med Wochenschr. 1996 Jun 22;126(25):1112-8. Unique Identifier : AIDSLINE MED/96281167; Zellweger JP; Association suisse contre la tuberculose et les maladies; pulmonaires, Berne.; Tuberculosis is currently a rare disease in Switzerland and its incidence is slowly decreasing. Nevertheless, the increase in the proportion of foreign-born patients, the occurrence of multidrug-resistant bacilli and the increase of tuberculosis in HIV-infected individuals giv
AIDS politics [letter]: Science. 1996 Aug 16;273(5277):859. Unique Identifier : AIDSLINE MED/96354942; Fox CH
Preventing AIDS [letter]: Science. 1996 Aug 16;273(5277):861. Unique Identifier : AIDSLINE MED/96354943; Benarde MA
Exclusion of Int-6 from PML nuclear bodies by binding to the HTLV-I Tax oncoprotein.: Science. 1996 Aug 16;273(5277):951-3. Unique Identifier : AIDSLINE MED/96337990; Desbois C; Rousset R; Bantignies F; Jalinot P; Centre National de la Recherche Scientifique UMR49, Ecole Normale; Superieure de Lyon, 69364 Lyon Cedex 07, France.; The Tax transactivator of the human T cell leukemia virus type I (HTLV-I) exhibits oncogenic properties. A screen for proteins interacting with Tax yielded a complementary DNA (cDNA) encoding the human Int-6 protein. In mice, the Int-6 gene can be converted into a putative dominant negative oncogene after retroviral i
Control of MHC restriction by TCR Valpha CDR1 and CDR2.: Science. 1996 Aug 16;273(5277):963-6. Unique Identifier : AIDSLINE MED/96337994; Sim BC; Zerva L; Greene MI; Gascoigne NRJ; Department of Immunology, The Scripps Research Institute, 10550; North Torrey Pines Road, La Jolla, CA 92037, USA. University of; Pennsylvania, Philadelphia, PA 1.; Individual T cell receptor (TCR) Valpha elements are expressed preferentially in CD4 or CD8 peripheral T cell subsets. The closely related Valpha3.1 and Valpha3.2 elements show reciprocal selection into CD4 and CD8 subsets, respectively. Transgenic mice expressing site-directed mutants of a Valpha3.1 gene were used to
[Human gene therapy]: Ryumachi. 1996 Feb;36(1):62-8. Unique Identifier : AIDSLINE MED/96359251; Shimada T
Sexual behaviour, contraceptive practice and reproductive health among school adolescents in rural Transkei.: S Afr Med J. 1996 May;86(5):523-7. Unique Identifier : AIDSLINE MED/96262229; Buga GA; Amoko DH; Ncayiyana DJ; Department of Obstetrics and Gynaecology, Univeralty of Transkei,; Umtata, E. Cape.; OBJECTIVES. To determine the patterns of sexual maturation, sexual behaviour, contraceptive practice and reproductive health among Transkeian adolescents. DESIGN. Cross-sectional descriptive study, using self administered questionnaires. SETTING. Twenty-six schools in 22 rural districts of the Transkei region of the E
Comparison of characteristics of patients and treatment outcome for pulmonary non-tuberculous mycobacterial infection and pulmonary tuberculosis.: Thorax. 1996 Feb;51(2):137-9. Unique Identifier : AIDSLINE MED/96246623; Al Jarad N; Demertzis P; Jones DJ; Barnes NC; Rudd RM; Gaya H; Wedzicha JA; Hughes DT; Empey DW; East London Tuberculosis Centre, London Chest Hospital, UK.; BACKGROUND: Patients with non-tuberculous mycobacteria are usually started on conventional antituberculous triple therapy once acid fast bacilli are detected, before the exact type of mycobacteria has been identified. The ability to identify the characteristics of patients with tuberculous and non-tuberculous mycobact
Increasing incidence of tuberculosis in the young and the elderly in Scotland.: Thorax. 1996 Feb;51(2):140-2. Unique Identifier : AIDSLINE MED/96246624; Duffield JS; Adams WH; Anderson M; Leitch AG; Respiratory Medicine Unit, Royal Infirmary Edinburgh NHS Trust,; UK.; BACKGROUND: Since 1987 there has been an arrest in the previously established decline of tuberculosis notifications in Scotland. A study was undertaken to determine whether age contributed to this phenomenon. METHODS: Notifications of tuberculosis in Scotland were quantified by year and age group for the years 1981-92
Pulmonary capillary blood volume in patients with probable pulmonary Kaposi's sarcoma.: Thorax. 1996 Feb;51(2):204-6. Unique Identifier : AIDSLINE MED/96246639; Camus F; de Picciotto C; Gerbe J; Roy S; Bouchaud O; Casalino E; Perronne C; Service d'Explorations Fonctionnelles, Hopital Bichat-Claude; Bernard, Paris, France.; BACKGROUND: An increase in pulmonary capillary blood volume secondary to angiogenesis has been described in Kaposi s sarcoma. The value of the pulmonary capillary blood volume as an early marker of pulmonary Kaposi s sarcoma was evaluated. METHODS: In a prospective study 45 HIV positive patients (nine asymptomatic for
Pulmonary diseases and HIV infection [letter]: Thorax. 1996 Feb;51(2):228. Unique Identifier : AIDSLINE MED/96246648; Fisher M; Asboe D; Gazzard BG
[Features of the status of otorhinolaryngologic organs of subway train mechanics]: Vestn Otorinolaringol. 1996 Mar-Apr;(2):17-21. Unique Identifier : AIDSLINE MED/96257062; Pankova VB; Vasil'eva SV; 337 mechanics exposed to chemical and physical hazards while servicing subway trains were examined for ENT status. Abnormalities were registered in 87.5% of the examinees. Frequent isolated and combined affections of the nose and pharynx occurred as a rule with mucosal dystrophy. Allergic conditions were not evident.
Women living with HIV: sexual behaviors and counseling experiences.: Women Health. 1995;23(4):17-26. Unique Identifier : AIDSLINE MED/96353421; Simoni JM; Mason HR; Marks G; Ruiz MS; Richardson JL; Department of Preventive Medicine, University of Southern; California, USA. jms112@columbia.edu; Seventy-two ethnically diverse women attending two outpatient HIV clinics in Los Angeles self-administered questionnaires. Nineteen women (26%) reported sexual activity in the two months prior to the survey; most were sexually monogamous and emotionally involved with live-in male partners. According to self-reports, 1
[Tropical spastic paraparesis due to HTLV-I. 4 case reports and literature review]: Acta Neurol Belg. 1996 Jun;96(2):117-25. Unique Identifier : AIDSLINE MED/96337399; Ossemann M; Duprez T; Sindic CJ; Service de Neurologie, Cliniques Universitaires Saint-Luc,; Bruxelles.; We describe the clinical, radiological, neurophysiological and biological characteristics of 4 patients suffering from tropical spastic paraparesis due to a HTLV-I infection. Patient 1 immigrated in Europe at the age of 16 from Caribbean islands. Patient 2 was a White male Caucasian who lived during several years with
An ecological assessment of community-based interventions for prevention and health promotion: approaches to measuring community coalitions.: Am J Community Psychol. 1996 Feb;24(1):33-61. Unique Identifier : AIDSLINE MED/96350870; Goodman RM; Wandersman A; Chinman M; Imm P; Morrissey E; Department of Public Health Sciences, Bowman Gray School of; Medicine, Winston-Salem, North Carolina 27157, USA.; Presented an ecological assessment of a community coalition to prevent alcohol, tobacco, and other drug abuse, and related risks. Ecological assessment is defined as occurring at multiple social levels and along a continuum of stages of coalition readiness. The assessment is aided by the triangulation, or combining of
Controlling diarrhea in the HIV patient.: Am J Nurs. 1996 Aug;96(8):35-41; quiz 42. Unique Identifier : AIDSLINE MED/96335042; Anastasi JK; Sun V; AIDS Program and Center for AIDS Research, Columbia University; School of Nursing, New York, NY, USA.
Tuberculosis control in resource-poor settings with high rates of HIV infection [editorial; comment]: Am J Public Health. 1996 Aug;86(8 Pt 1):1071-3. Unique Identifier : AIDSLINE MED/96326080; De Cock KM
Needle exchange programs and the law--time for a change [comment]: Am J Public Health. 1996 Aug;86(8 Pt 1):1077-8. Unique Identifier : AIDSLINE MED/96326084; Glantz LH; Mariner WK; School of Public Health Boston University, USA.
Is genital mycosis associated with HIV risk behaviors among heterosexuals? ACSF Investigators. Analyse des comportements sexuels en France.: Am J Public Health. 1996 Aug;86(8 Pt 1):1108-11. Unique Identifier : AIDSLINE MED/96326090; Warszawski J; Meyer L; Bajos N; INSERM U292, Hopital de Bicetre, France.; OBJECTIVES. This study examined in both sexes whether genital mycosis is as strongly associated with human immunodeficiency virus (HIV) sexual risk behavior as are other sexually transmitted diseases. METHODS. Heterosexuals in the French National Survey of Sexual Behavior who reported a history of either mycosis or an
A prospective study of syphilis and HIV infection among injection drug users receiving methadone in the Bronx, NY.: Am J Public Health. 1996 Aug;86(8 Pt 1):1112-5. Unique Identifier : AIDSLINE MED/96326091; Gourevitch MN; Hartel D; Schoenbaum EE; Selwyn PA; Davenny K; Friedland GH; Klein RS; Albert Einstein College of Medicine, Department of Epidemiology; and Social Medicine, Montefiore Medical Center, Bronx, NY 10467,; USA.; OBJECTIVES. The purpose of this study was to assess the relationship between syphilis and human immunodeficiency virus (HIV) infection in injection drug users. METHODS. A 6-year prospective study of 790 injection drug users receiving methadone maintenance treatment in the Bronx, NY, was conducted. RESULTS. Sixteen per
HIV infection and AIDS in China, 1985 through 1994.: Am J Public Health. 1996 Aug;86(8 Pt 1):1116-22. Unique Identifier : AIDSLINE MED/96326092; Yu ES; Xie Q; Zhang K; Lu P; Chan LL; Division of Epidemiology and Biostatistics, Graduate School of; Public Health, San Diego State University, CA 92182-0405, USA.; OBJECTIVES. This paper analyzes data on the distribution of and risk factors for the acquired immunodeficiency syndrome (AIDS) and human immunodeficiency virus (HIV) infection in China . METHODS. Ten years of data on persons tested for HIV infection and AIDS and the proportion who te
HIV risk behaviors among women living in low-income, inner-city housing developments.: Am J Public Health. 1996 Aug;86(8 Pt 1):1123-8. Unique Identifier : AIDSLINE MED/96326093; Sikkema KJ; Heckman TG; Kelly JA; Anderson ES; Winett RA; Solomon LJ; Wagstaff DA; Roffman RA; Perry MJ; Cargill V; Crumble DA; Fuqua RW; Norman AD; Mercer MB; Center for AIDS Intervention Research (CAIR), Medical College of; Wisconsin, Milwaukee 53226, USA.; OBJECTIVES. This study describes the prevalence and predictors of human immunodeficiency virus (HIV) risk behaviors among women living in low-income, inner-city housing developments. METHODS. Anonymous questionnaires were administered to 671 women living in 10 inner-city, low-income housing developments in five US cit
The Mpowerment Project: a community-level HIV prevention intervention for young gay men [see comments]: Am J Public Health. 1996 Aug;86(8 Pt 1):1129-36. Unique Identifier : AIDSLINE MED/96326094; Kegeles SM; Hays RB; Coates TJ; Center for AIDS Prevention Studies, University of California, San; Francisco 94105, USA.; OBJECTIVES. Since young gay men are engaging in alarmingly high rates of unsafe sex and few seek help for changing risky behaviors, community-level programs to prevent infection with the human immunodeficiency virus (HIV) among them are urgently needed. METHODS. We developed and implemented a community-level HIV preve
Directly observed therapy for tuberculosis: the Harlem Hospital experience, 1993.: Am J Public Health. 1996 Aug;86(8 Pt 1):1146-9. Unique Identifier : AIDSLINE MED/96326097; el-Sadr W; Medard F; Barthaud V; Division of Infectious Diseases, Harlem Hospital Center, New; York, NY 10037, USA.; OBJECTIVES. A directly observed therapy program was established at Harlem Hospital, New York, NY, in 1993 to promote high tuberculosis treatment completion rates. METHODS. The Harlem program used an on-site surrogate family model. Treatment completion rate, visit adherence rate, human immuno-deficiency virus seropreva
Death rates among patients hospitalized with community-acquired pneumonia: a reexamination with data from three states.: Am J Public Health. 1996 Aug;86(8 Pt 1):1152-4. Unique Identifier : AIDSLINE MED/96326099; Markowitz JS; Pashko S; Gutterman EM; Linde-Zwirble WT; Newbold R 3rd; Bristol-Myers Squibb Company, Princeton, NJ 08543-4500, USA.; OBJECTIVES. Death rates for community-acquired pneumonia based on relatively small-scale, published studies tend to exceed 15% to 20%. This study reexamined these estimates by using very large, population-based databases. METHODS. Death rates from 1993 associated with community-acquired pneumonia were reexamined with
HIV infection and risk behaviors among male port workers in Santos, Brazil.: Am J Public Health. 1996 Aug;86(8 Pt 1):1158-60. Unique Identifier : AIDSLINE MED/96326101; Larcerda R; Stall R; Gravato N; Tellini R; Hudes ES; Hearst N; Nucleo de Educacao E Prevencao-DST/AIDS, Municipality of; Santos, Sao Paulo, Brazil.; OBJECTIVES. This paper measured the extent to which human immunodeficiency virus (HIV) infection has spread among the male working-class population of Santos, Brazil . METHODS. Questionnaires on risk behaviors and blood tests were administered to a random sample (n = 395) of male po
Questioning the validity of self-reported heterosexual HIV transmission [letter]: Am J Public Health. 1996 Aug;86(8 Pt 1):1172. Unique Identifier : AIDSLINE MED/96326107; Brody S
Equianalgesic doses of subcutaneous but not intrathecal morphine alter phenotypic expression of cell surface markers and mitogen-induced proliferation in rat lymphocytes.: Anesthesiology. 1996 Aug;85(2):355-65. Unique Identifier : AIDSLINE MED/96322830; Hamra JG; Yaksh TL; Department of Anesthesiology, University of California, San; Diego, La Jolla 92093-0818, USA.; BACKGROUND: Surgical trauma and opioids are linked with suppression of immune function. Evidence suggests a probable supraspinal action of morphine in altering immune function, although the role of spinal systems have not been evaluated. Therefore, this study compared the effect of equianalgesic doses of subcutaneous
[Prevalence of HIV infection in Italian drug users attending drug treatment centers in the years 1990-92]: Ann Ist Super Sanita. 1995;31(3):301-5. Unique Identifier : AIDSLINE MED/96308288; Rezza G; Alliegro MB; De Rose A; Pezzotti P; Serafin I; Centro Operativo AIDS, Istituto Superiore di Sanita, Roma.; Repeated cross-sectional surveys have been conducted to collect information on the trend of HIV prevalence among drug users attending drug treatment centers in Italy in the years 1990-92. Annual HIV prevalence was 31.5% in 1990, 29.1% in 1991, and 24.6% in 1992, showing a declining
[Health education and the prevention of HIV infection in schools]: Ann Ist Super Sanita. 1995;31(3):307-12. Unique Identifier : AIDSLINE MED/96308289; Bertinato L; Poli S; Caffarelli E; Mirandola M; Greco D; Laboratorio di Epidemiologia e Biostatistica, Istituto Superiore; di Sanita; This review describes the HIV prevention strategies adopted since 1990 by the Italian Ministry of Health and Ministry of Education, coordinated by the National Health Institute, for use in Italian schools. It sets out reasons for believing that action in schools is essential in containing the spread of the HIV epidemi
Effects of coffee cherry on the immune system in SHN mice.: Anticancer Res. 1996 Jul-Aug;16(4A):1827-30. Unique Identifier : AIDSLINE MED/96314430; Kobayashi T; Yasuda M; Iijima K; Toriizuka K; Cyong JC; Nagasawa H; Experimental Animal Research Laboratory, Meiji University,; Kawasaki, Japan.; Previously, we found that chronic ingestion of the extract of coffee cherry (CC), the residue after the removal of coffee beans, induced a marked suppression of the development and the growth of spontaneous mammary tumours in a high mammary tumour strain of SHN mice. As a possible step to clarify the mechanism of this
Pulmonary complications of HIV infection.: Annu Rev Med. 1996;47:117-26. Unique Identifier : AIDSLINE MED/96266631; Murray JF; Division of Pulmonary and Critical Care Medicine, San Francisco; General Hospital Medical Center, University of California 94143,; USA.; Pulmonary disease is a major source of morbidity and mortality in HIV-infected persons. Pneumocystis carinii pneumonia has decreased substantially during the last eight years, but in the United States it remains the most common disorder that announces the onset of AIDS. In contrast, tu
Bartonella (Rochalimaea) infections: beyond cat scratch.: Annu Rev Med. 1996;47:355-64. Unique Identifier : AIDSLINE MED/96266650; Schwartzman W; Department of Medicine, Sepulveda VA Medical Center, California; 91343, USA.; Five species of Bartonella have been found to infect humans, henselae, quintana, elizabethae, bacilliformis, and vinsonii. The most common of these in North America are Bartonella quintana and Bartonella henselae, the agents of trench fever, bacillary angiomatosis , and parenc
Abnormal serum porphyrin levels in patients with the acquired immunodeficiency syndrome with or without hepatitis C virus infection.: Arch Dermatol. 1996 Aug;132(8):906-10. Unique Identifier : AIDSLINE MED/96326140; Nomura N; Zolla-Pazner S; Simberkoff M; Kim M; Sassa S; Lim HW; Dermatology Laboratory Medicine, New York Veterans Affairs; Medical Center, New York, NY, USA.; OBJECTIVE: To define the contributions of human immunodeficiency virus (HIV) and hepatitis C virus infections to the development of porphyria cutanea tarda. DESIGN: Analysis of serum porphyrin levels in a cohort of 167 subjects. Serum samples were divided into 4 groups corresponding to the status of HIV and hepatitis
Disseminated strongyloidiasis in a patient with acquired immunodeficiency syndrome [letter]: Arch Dermatol. 1996 Aug;132(8):977-8. Unique Identifier : AIDSLINE MED/96326157; Kao D; Murakawa GJ; Kerschmann R; Berger T
High prevalence of arthropathy in HTLV-I carriers on a Japanese island.: Ann Rheum Dis. 1996 Mar;55(3):193-5. Unique Identifier : AIDSLINE MED/96246446; Motokawa S; Hasunuma T; Tajima K; Krieg AM; Ito S; Iwasaki K; Nishioka K; Department of Orthopaedics, Nagasaki Chuo National Hospital,; Japan.; OBJECTIVE: To determine the aetiological relationship between human T cell leukaemia virus type-I (HTLV-I) and arthritis, by performing an epidemiological study of the inhabitants of Tsushima, an island northwest of the main island of Kyushu, Japan , which is an endemic area of HTLV-
Pathology of microsporidiosis: emerging parasitic infections in patients with acquired immunodeficiency syndrome.: Arch Pathol Lab Med. 1996 Feb;120(2):173-88. Unique Identifier : AIDSLINE MED/96197783; Schwartz DA; Sobottka I; Leitch GJ; Cali A; Visvesvara GS; Department of Pathology, Emory University School of Medicine,; Atlanta, GA, USA.; OBJECTIVE: Microsporidiosis is a group of rapidly emerging protozoan infections that have thus far been reported predominantly from severely immunosuppressed persons with the acquired immunodeficiency syndrome (AIDS). The four genera that have been identified in AIDS patients (Enterocytozoon, Encephalitozoon, Septata,
Visceral leishmaniasis emerging as an important opportunistic infection in HIV-infected persons living in areas nonendemic for Leishmania donovani.: Arch Pathol Lab Med. 1996 Feb;120(2):189-98. Unique Identifier : AIDSLINE MED/96197784; Albrecht H; Sobottka I; Emminger C; Jablonowski H; Just G; Stoehr A; Kubin T; Salzberger B; Lutz T; van Lunzen J; Department of Internal Medicine, University Clinic Eppendorf,; Hamburg, Germany.; BACKGROUND: Visceral leishmaniasis is an important infection in patients infected with human immunodeficiency virus and living in areas endemic for Leishmania sp. Leishmaniasis, however, is rarely suspected in patients residing in nonendemic countries. METHODS: Retrospective case analysis of 15 patients with human imm
Autopsy verification of Encephalitozoon intestinalis (microsporidiosis) eradication following albendazole therapy.: Arch Pathol Lab Med. 1996 Feb;120(2):199-203. Unique Identifier : AIDSLINE MED/96197785; Joste NE; Rich JD; Busam KJ; Schwartz DA; Department of Pathology, Brigham and Women's Hospital, Boston,; MA, USA.; Microsporidian infections are increasingly recognized as an important cause of morbidity for persons infected with the human immunodeficiency virus. Encephalitozoon (formerly Septata) intestinalis is a recently described microsporidian that causes intestinal and disseminated infections in severely immunocompromised pa
Bone allograft banking in South Australia [letter]: Aust N Z J Surg. 1996 Aug;66(8):562-3. Unique Identifier : AIDSLINE MED/96332274; Bryce SL; Journeaux SF
Viral exanthems in childhood.: Australas J Dermatol. 1996 May;37 Suppl 1:S14-6. Unique Identifier : AIDSLINE MED/96311863; Hogan PA; Department of Dermatology, Royal Alexandra Hospital for Children,; Sydney, New South Wales, Australia.; Viral exanthems can be classified as erythematous vesicular and papular. The majority are erythematous with the most common viral causes being non polio enteroviruses, respiratory viruses, acute. Epstein-Barr virus, human herpes viruses 6 and 7, and parvovirus B-19. Measles, rubella, mumps, acute GMV, hepatitis viruse
Human T lymphotropic virus-1 infection.: Australas J Dermatol. 1996 May;37 Suppl 1:S20-2. Unique Identifier : AIDSLINE MED/96311865; Kanzaki T; Setoyama M; Katahira Y; Department of Dermatology, Kagoshima University Faculty of; Medicine, Japan.; Human T lymphotropic virus-1 (HTLV-1) is a retrovirus which infects T lymphocytes (CD4+) to cause adult T cell leukaemia/lymphoma (ATL), tropical spastic para-paresis and several other HTLV-1 associated disorders. ATL has been reported worldwide but areas of high incidence include Japan
Immunity to eimeria tenella in chickens: phenotypical and functional changes in peripheral blood T-cell subsets.: Avian Dis. 1996 Jan-Mar;40(1):37-48. Unique Identifier : AIDSLINE MED/96253338; Breed DG; Dorrestein J; Vermeulen AN; Department of Parasitology, Intervet International BV, Boxmeer,; The Netherlands.; The changes in peripheral blood leukocyte (PBL) T-cell subsets following Eimeria tenella infection in outbred white leghorn chickens were studied, using a panel of murine monoclonal antibodies specific for the chicken homologues of the mammalian CD3, CD8, and CD4 markers on day-to-day samples of PBLs. Both flow cytome
[Muscular involvement in the course of AIDS. Anatomo-clinical study of 17 cases]: Ann Pathol. 1995;15(6):424-30. Unique Identifier : AIDSLINE MED/96318055; Butori C; Desnuelle C; Hofman P; Paquis V; Durant J; Carles M; Pesce A; Michiels JF; Service d'Anatomo-Pathologie, CHU Nice.; We report 17 patients seropositive for the human immunodeficiency virus, with muscle tissue involvement in different stages of the disease. Some patients are treated with azidothymidine ( AZT ). Others have no opportunistic infections. In all cases, the
Radiographic presentation of pulmonary tuberculosis in severely immunosuppressed HIV-seropositive patients.: Am J Emerg Med. 1996 Jul;14(4):359-63. Unique Identifier : AIDSLINE MED/96331138; Asimos AW; Ehrhardt J; Department of Emergency Medicine, Carolinas Medical Center,; Charlotte, NC 28232-2861, USA.; Although the presence of typical postprimary or reactivation pattern tuberculosis (TB) on chest radiograph (CXR) strongly suggests TB infection in adults, the sensitivity of this finding, particularly in severely immunosuppressed human immunodeficiency virus (HIV) patients, is unclear. To investigate this issue, HIV s
Analysis of genetic heterogeneity, antigenicity, and biological characteristics of HIV-1 in a maternal transmitter and nontransmitter patient pair.: DNA Cell Biol. 1996 Jul;15(7):571-80. Unique Identifier : AIDSLINE +; Ayyavoo V; Ugen KE; Fernandes LS; Goedert JJ; Rubinstein A; Williams WV; Weiner DB; Department of Pathology, University of Pennsylvania, Philadelphia; 19104, USA.; To obtain insight into the factors involved in vertical transmission, we compared the sequence diversity, seroreactivity, and biological characteristics of human immunodeficiency virus type 1 (HIV-1) derived from a transmitter and nontransmitter mother pair. Forty-two clones from the transmitter and 20 from the nontra
A molecular mechanics and dynamics study of alternate triple-helices involving the integrase-binding site of the HIV-1 virus and oligonucleotides having a 3'-3' internucleotide junction.: J Biomol Struct Dyn. 1996 Apr;13(5):835-53. Unique Identifier : AIDSLINE MED/96304778; Ouali M; Bouziane M; Ketterle C; Gabarro-Arpa J; Auclair C; Le Bret M; Laboratoire de Physicochimie des Macromolecules Biologiques,; Villejuif, France.; Triple helix formation by oligonucleotides can be extended beyond polypurine tracts with the help of specially designed linkers. In this paper we focus our attention on the integrase-binding site of the HIV-1 virus located on the U5 LTR end which contains two adjacent purine tracts on opposite strands. Two alternate t
Direct-rapid (DR) mutagenesis of large plasmids using PCR.: Biotechniques. 1995 Oct;19(4):559-64. Unique Identifier : AIDSLINE MED/96113672; Gatlin J; Campbell LH; Schmidt MG; Arrigo SJ; Department of Microbiology and Immunology, Medical University of; South Carolina, Charleston 29425-2230, USA.
Detection of DNA in single cells using an automated cell deposition unit and PCR.: Biotechniques. 1995 Oct;19(4):616-20. Unique Identifier : AIDSLINE MED/96113684; Bertram S; Hufert FT; Neumann-Haefelin D; von Laer D; Abteilung Virologie, Inst. fur Medizinische Mikrobiologie und; Hygiene, Universitat Freiburg, Germany.; A highly effective single-cell PCR method using a fluorescence-activated cell sorting (FACS)-based automated cell deposition unit (ACDU) that sorts single cells directly into PCR tubes was developed. To evaluate the sensitivity of this method, single ACH-2 cells (containing one HIV-1 genome per cell) were sorted, and
Patient report of HIV risk screening by primary care physicians.: Am J Prev Med. 1996 Mar-Apr;12(2):116-22. Unique Identifier : AIDSLINE MED/96269142; Wenrich MD; Carline JD; Curtis JR; Paauw DS; Ramsey PG; Department of Medicine, University of Washington, Seattle; 98195-5302, USA.; Our objectives were to (1) assess primary care physicians performance at screening patients for HIV risks using patient report; (2) compare patient recall concerning screening with physician report; and (3) compare HIV risk screening with general preventive health screening. Up to 20 patients from 126 physicians pra
[TCR alpha beta + CD4- CD8- T cells among the peripheral blood mononuclear cells of myasthenia gravis patients]: No To Shinkei. 1996 Jul;48(7):644-7. Unique Identifier : AIDSLINE MED/96303748; Nagane Y; Utsugisawa K; Matsubara R; Yamagata M; Tohgi H; Department of Neurology, School of Medicine, Iwate Medical; University, Morioka, Japan.; We investigated the occurrence of TCR alpha beta + CD4- CD8- mononuclear cells (DN alpha beta T cells) and TCR gamma delta + CD3+ mononuclear cells (gamma delta T cells) among the peripheral blood mononuclear cells of 22 myasthenia gravis patients (MG) and 22 controls in order to examine whether extrathymic T cell sub
Federal health initiatives: a status report [news]: Dermatol Nurs. 1996 Jun;8(3):199-200. Unique Identifier : AIDSLINE MED/96360618; Wakefield MK
Volunteers needed for study of HIV viral load test [news]: Oncology (Huntingt). 1996 Apr;10(4):449-50. Unique Identifier : AIDSLINE MED/96300571
Bearing the brunt of poverty.: Nurs Stand. 1996 May 1;10(32):25-7. Unique Identifier : AIDSLINE MED/96356908; Henriques J
Awareness is the cure [news]: Nurs Stand. 1996 May 29;10(36):17. Unique Identifier : AIDSLINE MED/96356916; Williams K
AIDS, euthanasia and nursing.: Nurs Stand. 1996 May 29;10(36):49-51. Unique Identifier : AIDSLINE MED/96356927; Ogden R; Requests for euthanasia can pose a dilemma for nurses. Some of the arguments for and against euthanasia are presented here together with a summary of a study into the phenomenon of underground euthanasia. These are considered in relation to the law and nursing ethics.
Can I have an AIDS test?: Nurs Stand. 1996 May 29;10(36):52-4. Unique Identifier : AIDSLINE MED/96356928; Ford J; Nurses in all areas will increasingly come into contact with people concerned about HIV infection. Although pre- and post-test counselling should be performed by those specially trained for it, sound knowledge about the physical, psychological, emotional and social effects of HIV will help nurses offer reassurance and
AIDS. Sharing knowledge.: Nurs Stand. 1996 May 29;10(36):55-6. Unique Identifier : AIDSLINE MED/96356929; George M; There is a large and growing demand for HIV/AIDS services among residents of east London. Many of those infected or affected are refugees or asylum seekers who often fear statutory agencies.
Has the incidence of AIDS reached its peak? [news]: Ann Oncol. 1996 Feb;7(2):108. Unique Identifier : AIDSLINE MED/96262285
The challenge of HIV/AIDS related eye disease [editorial; comment]: Br J Ophthalmol. 1996 Jun;80(6):496-7. Unique Identifier : AIDSLINE MED/96334756; Courtright P
Carcinoma of the conjunctiva and HIV infection in Uganda and Malawi [see comments]: Br J Ophthalmol. 1996 Jun;80(6):503-8. Unique Identifier : AIDSLINE MED/96334759; Waddell KM; Lewallen S; Lucas SB; Atenyi-Agaba C; Herrington CS; Liomba G; Uganda Eye Project, Kampala, Uganda.; AIM--To investigate the association of human immunodeficiency virus (HIV) infection and carcinoma of the conjunctiva in Africa, and the role of human papilloma virus type 16 (HPV-16). METHODS--Patients in Uganda and Malawi presenting to eye clin
[Exudative uveitis, chronic labial herpes and interstitial pneumonia in an HIV-positive child]: Oftalmologia. 1996 Jan-Mar;40(1):35-8. Unique Identifier : AIDSLINE MED/96308171; Popa GC; Clinica Oftalmologica Craiova.; The paper presents the case of a 6 and a half year-old child, with marked hipotrophy in height and weight (15 kg weight, which make a deficit of about 6 kg). The right eye presented pupilar sinekies, loaded vitreous and two white-yellow exsudative coroidal placards. One of them was inter-maculo-papilar having 4DP in d
HIV-1 genome dimerization: formation kinetics and thermal stability of dimeric HIV-1Lai RNAs are not improved by the 1-232 and 296-790 regions flanking the kissing-loop domain.: Biochemistry. 1996 Jul 23;35(29):9366-74. Unique Identifier : AIDSLINE MED/96302233; Laughrea M; Jette L; McGill AIDS Centre, Lady Davis Institute for Medical Research,; Sir Mortimer B. Davis-Jewish General Hospital, Montreal, Quebec,; Canada.; The genome of all retroviruses consists of two identical RNAs noncovalently linked near their 5 end. Dimerization of genomic RNA is thought to modulate several steps in the retroviral life cycle, such as recombination, translation, and encapsidation. The kissing-loop model of HIV-1 genome dimerization posits that the
Quantitative hybridization kinetics of DNA probes to RNA in solution followed by diffusional fluorescence correlation analysis.: Biochemistry. 1996 Aug 6;35(31):10182-93. Unique Identifier : AIDSLINE MED/96322339; Schwille P; Oehlenschlager F; Walter NG; Max-Planck-Institute for Biophysical Chemistry, Department of; Biochemical Kinetics, Gottingen, Germany.; Binding kinetics in solution of six N,N,N ,N -tetramethyl-5-carboxyrhodamine-labeled oligodeoxyribonucleotide probes to a 101mer target RNA comprising the primer binding site for HIV-1 reverse transcriptase were characterized using fluorescence correlation spectroscopy (FCS). FCS allows a sensitive, non-radioactive re
Solution NMR evidence that the HIV-1 protease catalytic aspartyl groups have different ionization states in the complex formed with the asymmetric drug KNI-272.: Biochemistry. 1996 Aug 6;35(31):9945-50. Unique Identifier : AIDSLINE MED/96322311; Wang YX; Freedberg DI; Yamazaki T; Wingfield PT; Stahl SJ; Kaufman JD; Kiso Y; Torchia DA; Molecular Structural Biology Unit, NIDR, National Institutes of; Health, Bethesda, Maryland 20892, USA.; In order to improve the design of HIV-1 protease inhibitors , it is essential to understand how they interact with active site residues, particularly the catalytic Asp25 and Asp125 residues. KNI-272 is a promising, potent HIV-1 protease inhibitor (K(i) approximately
Adolescents' perceived risk for STDs and HIV infection.: J Adolesc Health. 1996 Mar;18(3):177-81. Unique Identifier : AIDSLINE MED/96253617; Ellen JM; Boyer CB; Tschann JM; Shafer MA; Department of Pediatrics, University of California, San Francisco; 94143, USA.; PURPOSE: (1) To determine whether adolescents systematically underestimate their relative risk for STDs and HIV; and (2) to determine to what extent anxiety about STDs and HIV, past condom use, number of lifetime partners and STD/HIV-related beliefs predict perceived relative risk. METHODS: Two hundred and thirty-one
Healthcare workers and bloodborne pathogens: knowledge, concerns, and practices.: Gastroenterol Nurs. 1996 May-Jun;19(3):96-101. Unique Identifier : AIDSLINE MED/96356733; Ryan ME; Jones L; Miller D; Occupational exposure of healthcare workers to bloodborne pathogens and the transmission of human immunodeficiency virus and hepatitis B virus warrant study. This study examined issues related to the transmission of bloodborne pathogens in practice. Findings provide information regarding knowledge level, practices of
[Disseminated histoplasmosis in a patient infected with the HIV (letter)]: Enferm Infecc Microbiol Clin. 1996 Jan;14(1):60-1. Unique Identifier : AIDSLINE MED/96306179; Rubio A; Unzaga MJ; Baraia-Etxaburu J; Teira R; Rojo P; Cisterna R; Santamaria JM
[Coxofemoral infectious arthritis caused by Candida albicans in an HIV seropositive patient (letter)]: Enferm Infecc Microbiol Clin. 1996 Jan;14(1):63-4. Unique Identifier : AIDSLINE MED/96306182; Rodriguez-Escudero MJ; Solera J; Martinez Alfaro E; Saez L
[Pneumocystis carinii pneumonia. Diagnosis using immunofluorescence with monoclonal antibodies (letter)]: Enferm Infecc Microbiol Clin. 1996 Jan;14(1):64-5. Unique Identifier : AIDSLINE MED/96306183; Cruz Villuendas M; Antonia Remacha M; Echavarri B; Carlos Paradineiro J; Ramos C; Luisa Aisa M
[Primary cutaneous cryptococcosis and bacterial pneumonia caused by Pseudomonas aeruginosa in AIDS: clinical case and review of the literature]: Enferm Infecc Microbiol Clin. 1996 Feb;14(2):101-5. Unique Identifier : AIDSLINE MED/96307904; Dronda F; Gonzalez-Lopez A; Fernandez-Martin JI; Alonso-Sanz M; Chaves F; Lopez-Cubero L; Unidad de Enfermedades Infecciosas-Microbiologia, Hospital; General Penitenciario, Madrid.; BACKGROUND: Clinically symptomatic infection due to Cryptococcus neoformans is found in 5-10% of patients with AIDS. It usually appears as meningitis with or without associated blood stream infection. In the last years, severe Pseudomonas aeruginosa infections in HIV (+) patients, with a high morbidity and mortality,
[Acute renal insufficiency caused by a sulfadiazine in a patient with cerebral toxoplasmosis and AIDS (letter)]: Enferm Infecc Microbiol Clin. 1996 Feb;14(2):125-7. Unique Identifier : AIDSLINE MED/96307912; Rodriguez-Carballeira M; Casagran A; More J; Argilaga R; Garcia M
[Tuberculin test in HIV infection]: Enferm Infecc Microbiol Clin. 1996 Feb;14(2):90-5. Unique Identifier : AIDSLINE MED/96307902; Portu JJ; Perez JR; Arevalo JM; Aldamiz-Etxebarria M; Agud JM; Ayensa C; Servicio de Medicina Interna, Hospital Txagorritxu, Condado de; Trevino.; BACKGROUND: Intravenous infected-HIV drug abusers (IDAP/HIV+) are known to have a higher risk of tuberculosis (TB) than others. The effectiveness of tuberculin testing (Mantoux) in the detection of the TB infection in HIV(+) patients is probably lower than HIV(-) individuals. The aim of this paper is to assess tubercu
Deficient quantitative expression of CD45 isoforms on CD4+ and CD8+ T cell subpopulations and subsets of CD45RA(low)CD45RO(low) T cells in newborn blood.: Biol Neonate. 1996;69(2):128-32. Unique Identifier : AIDSLINE MED/96282141; Chheda S; Palkowetz KH; Rassin DK; Goldman AS; Department of Pediatrics, University of Texas Medical Branch,; Galveston 77555-0526, USA.; Deficiencies in the quantitative expression of CD45RA and CD45RO on CD4+ and CD8+ T cells and in a population of CD45RA(low)CD45RO(low) T cells in blood from term newborn infants were found by flow cytometry. The relative frequencies of CD45RO on CD4+ T cells from adults and newborn infants were 72 and 58%, respective
[Evaluation of an informative leaflet on AIDS/HIV infection aimed at primary health care professionals in Catalonia]: Aten Primaria. 1996 Jan;17(1):4-10. Unique Identifier : AIDSLINE MED/96308237; Rodes A; Aguilera R; Blanch C; Casabona J; Departament de Sanitat i Seguretat Social, Programa per a la; Prevencio i el Control de la SIDA.; OBJECTIVE: To assess primary care professionals understanding and acceptance of a periodic information leaflet on HIV/AIDS. DESIGN: Crossover. SETTING: Primary care teams from the Institut Catala de la Salut. PARTICIPANTS: A random sample of 300 doctors, qualified nurses and social workers. INTERVENTION: A self-admin
[AIDS and tuberculosis (editorial)]: Aten Primaria. 1996 Mar 31;17(5):307-8. Unique Identifier : AIDSLINE MED/96318376; Gimenez i Masat A
The pathology of cervical neoplasia.: Curr Opin Obstet Gynecol. 1996 Feb;8(1):69-73. Unique Identifier : AIDSLINE MED/96260578; Ostor AG; Mulvany N; Department of Anatomical Pathology and Cytology, Royal Women's; Hospital, Melbourne, Australia.; The World Health Organization classification has clarified the typing of cervical tumours. The category of early stromal invasion has been eliminated from the International Federation of Gynecology and Obstetrics staging scheme of cervical carcinoma. Stage lal is defined now as depth o
HIV-1-associated pathology in hemato-lymphoid organs and the experimental evaluation in the SCID-hu mouse.: Int J Hematol. 1996 Jun;63(4):253-64. Unique Identifier : AIDSLINE MED/96292989; Kaneshima H; HIV Gene Therapy/Pathogenesis Research SyStemix, Inc., Palo Alto,; CA 94304, USA. hkaneshima@stem.com; A variety of possible mechanisms for the loss of CD4+ T cells has been proposed, such as direct cytopathic effects by HIV-1 infection, and indirect induction of apoptosis. However, the fundamental picture of major and central pathogenic processes for the decay of immune systems is still missing in understanding the pa
Helicobacter pylori infection in the etiopathogenesis of duodenal ulcer in children.: J Physiol Pharmacol. 1996 Mar;47(1):209-20. Unique Identifier : AIDSLINE MED/96261544; Bak-Romaniszyn L; Malecka-Panas E; Zeman K; Czkwianianc E; Kozlowski W; Kulig A; Kaluzynski A; Suski S; Dept of Pediatrics, Military Medical University, Lodz, Poland.; The study evaluates the frequency of Helicobacter pylori (H. pylori) infection, as well as systemic cellular immune response to H. pylori in children with duodenal ulcer (DU). The study group comprised 47 children with DU, aged 6-17 (mean 13, 1 +/- 4, 2). H. pylori detection was based on urease test, histology, cultur
Uptake and metabolism of BuCast: a glycoprotein processing inhibitor and a potential anti-HIV drug.: Glycobiology. 1996 Mar;6(2):209-16. Unique Identifier : AIDSLINE MED/96285861; Kang MS; Hoechst Marion Roussel Inc., Cincinnati, OH 45215, USA.; We have previously shown (Sunkara et al., 1989; Taylor et al., 1991) that 6-o-butanoyl castanospermine (BuCast) was a 30-50-fold better inhibitor of HIV syncytia formation than castanospermine (Cast). Radiolabeled Cast and BuCast were used to study the uptake and metabolism of these compounds in cultured cells and in
Infection control: human T-cell leukaemia virus infection.: Br J Nurs. 1996 May 9-22;5(9):529-34. Unique Identifier : AIDSLINE MED/96356659; Kepple J; Human T-cell leukaemia (HTLV) types I and II are blood-borne viruses which are transmissible by sexual contact, transfusion of infected blood, sharing equipment for intravenous drug use and breast-feeding. At present the estimated seroprevalence of these viruses in the UK is approximately 1 in 20,000. HTLV I/II infect
[Patient education about autologous blood donation (editorial; comment)]: Infusionsther Transfusionsmed. 1996 Apr;23(2):66. Unique Identifier : AIDSLINE MED/96271997; Weissauer W
[Degree of patient education retardation preoperative autologous blood donation at a university clinic (see comments)]: Infusionsther Transfusionsmed. 1996 Apr;23(2):67-70. Unique Identifier : AIDSLINE MED/96271998; Nussbaumer W; Mayer W; Schonitzer D; Zentralinstitut fur Bluttransfusion und Immunologische; Abteilung, Universitatsklinik Innsbruck, Osterreich.; OBJECTIVE. Uncovering the low degree of information in autologous blood donors for the purpose of implementation of corrective measures. DESIGN. Questionnaire for autologous blood donors. SETTING. Department for Transfusion Medicine of a University Clinic. PARTICIPANTS. 174 autologous blood donors, selected by their r
National Advisory Committee on Immunization (NACI). Interim advisory on measles revaccination of persons with acquired immunodeficiency syndrome (AIDS).: Can Commun Dis Rep. 1996 Jul 15;22(14):116-7. Unique Identifier : AIDSLINE MED/96333977
The safety of immune globulins.: Can Commun Dis Rep. 1996 Jul 15;22(14):117-9. Unique Identifier : AIDSLINE MED/96333978; Tepper M; Gully P; Blood-borne Pathogens Division, Bureau of Infectious Diseases,; LCDC, Ottawa, Ontario.
Studies of the degradation products of nisin, a peptide antibiotic, using capillary electrophoresis with off-line mass spectrometry.: J Chromatogr A. 1996 May 31;735(1-2):375-85. Unique Identifier : AIDSLINE MED/96276293; Cruz L; Garden RW; Kaiser HJ; Sweedler JV; Department of Chemistry, University of Illinois at; Urbana-Champaign 61801, USA.; The utility of capillary electrophoresis (CE) for assessing the purity and stability of pharmaceutical peptides is investigated. The degradation of nisin, a pentacyclic peptide antibiotic, depends upon sample preparation and storage conditions and is followed by CE. With conventional UV detection, peaks are not identi
[The First National Scientific and Practical Conference on the Problems of HIV/AIDS with international participation]: Mikrobiol Z. 1996 Jan-Feb;58(1):108-11. Unique Identifier : AIDSLINE MED/96365157; Spivak MIa
Revisiting the psychological aspects of AIDS: has the crisis passed? [editorial]: Br J Hosp Med. 1996 Feb 21-Mar 5;55(4):158-9. Unique Identifier : AIDSLINE MED/96259710; Ratigan BJ
AIDS-related lymphoma: an emerging epidemic.: Br J Hosp Med. 1996 Mar 6-19;55(5):282-8. Unique Identifier : AIDSLINE MED/96259742; Denton AS; Brook MG; Miller RF; Spittle MF; Meyerstein Institute, University College London Medical School,; Middlesex Hospital.; Acquired immunodeficiency syndrome-related lymphoma is a serious opportunistic complication of human immunodeficiency virus (HIV) infection which is predicted to increase in frequency over the next few years. The presence of this malignant process in HIV-related individuals, who are already immunocompromised, constitu
[Bronchogenic carcinoma and human immunodeficiency virus infection]: Arch Bronconeumol. 1995 Aug-Sep;31(7):362-4. Unique Identifier : AIDSLINE MED/96241364; Carrasquer C; Nieto ML; Soldevila D; Blanes M; Ferrer JM; Perpina M; Servicio de Neumologia, Hospital Universitario La Fe, Valencia.; The coexistence of bronchogenic carcinoma and human immunodeficiency virus is unusual. Patients are usually young former smokers and histopathologic type is most often adenocarcinoma. We describe two cases of bronchogenic carcinoma in HIV positive individuals.
[The campaign against HIV and AIDS: widening the field of action (editorial)]: Sante. 1995 Sep-Oct;5(5):271-3. Unique Identifier : AIDSLINE MED/96108281; Piot P; Cherney S
[Specifics of the management of HIV infection in Maghreb]: Sante. 1995 Sep-Oct;5(5):275-7. Unique Identifier : AIDSLINE MED/96108282; Himmich H; Chakib A; Service des maladies infectieuses, CHU Ibn Rochd, Casablanca,; Maroc.
[Impact of AIDS on the resurgence of tuberculosis and reduced availability of hospital beds in Brazzaville (Congo)]: Sante. 1995 Sep-Oct;5(5):278-82. Unique Identifier : AIDSLINE MED/96108283; Loemba H; Beuzit Y; Makuwa M; Hopital central des armees, Departement de medecine,; Brazzaville, Congo.; Our objective was twofold: firstly to evaluate the impact of AIDS on the annual increase of tuberculosis morbidity in Brazzaville; and secondly, to show its consequences on the reduced availability of hospital beds for patients treated for diseases nonrelated to AIDS. This retrospective study included 541 tuberculosis
[Research in Africa]: Sante. 1995 Sep-Oct;5(5):283-5. Unique Identifier : AIDSLINE MED/96108284; Levy JP
[AIDS epidemiology in French-speaking, central Africa]: Sante. 1995 Sep-Oct;5(5):287-90. Unique Identifier : AIDSLINE MED/96108285; Kapita B; Service de medecine interne, Hopital de Mama-Yemo, Kinsha,; Zaire.
The school environment and health.: Promot Educ. 1996 Mar;3(1):10-4, 41-2. Unique Identifier : AIDSLINE MED/96298104; Williams JH; National Education Association of the United States, Health; Information Network, Washington, DC 20036-3290, USA.
Case report: Kaposi's sarcoma of the rectum--treatment with radiation therapy.: Br J Radiol. 1996 Jun;69(822):573-4. Unique Identifier : AIDSLINE MED/96318194; Kaufmann T; Nisce LZ; Coleman M; Department of Radiation Oncology, New York Hospital-Cornell; Medical Center, Cornell University Medical College, New York, New; York, USA.; The number of patients afflicted with the acquired immune deficiency syndrome (AIDS) is on the rise. About 30% of AIDS patients develop Kaposi s sarcoma. Although the skin is the most common site of involvement, lesions may encompass the gastrointestinal tract. The purpose of this report is to describe a patient with
Mycobacterium avium and purified protein derivative-specific cytotoxicity mediated by CD4+ lymphocytes from healthy HIV-seropositive and-seronegative individuals.: J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Aug 15;12(5):433-41. Unique Identifier : AIDSLINE MED/96335104; Ravn P; Pedersen BK; Department of Infectious Diseases, Rigshospitalet, Copenhagen,; Denmark.; HIV is the greatest single risk factor for the development of tuberculosis. Diseases caused by M. tuberculosis and mycobacteria are the most common opportunistic infections in HIV-infected persons, which may stem from a functional defect of the CD4+ T-cell-mediated killing of macrophages harboring mycobacteria. Our ob
The immunosuppressive peptide of HIV-1 inhibits T and B lymphocyte stimulation.: J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Aug 15;12(5):442-50. Unique Identifier : AIDSLINE MED/96335105; Denner J; Persin C; Vogel T; Haustein D; Norley S; Kurth R; Paul-Ehrlich-Institute, Langen/Frankfurt, Germany.; The transmembrane glycoproteins of all retroviruses contain a conserved region composed of a leucine zipper, an immunosuppressive domain, and an immunodominant Cys-Cys loop. The amino acid sequence of the immunosuppressive domain of gp41 of human immunodeficiency virus type 1 (HIV-1; amino acids 583-599) is closely re
Antiviral efficacy and toxicity of ribavirin in murine acquired immunodeficiency syndrome model.: J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Aug 15;12(5):451-61. Unique Identifier : AIDSLINE MED/96335106; Harvie P; Omar RF; Dusserre N; Desormeaux A; Gourde P; Tremblay M; Beauchamp D; Bergeron MG; Centre de Recherche en Infectiologie, Centre Hospitalier de; l'Universite Laval, Quebec, Canada.; The antiretroviral efficacy and hematotoxicity of ribavirin, a guanosine analogue, have been evaluated in mice infected with the LP-BM5 virus pool [murine acquired immunodeficiency syndrome (MAIDS) model]. Doses ranging from 6.25 to 200 mg/kg/day were injected intraperitoneally twice a day for 6 weeks to infected mice
A randomized trial (ISS 901) of switching to didanosine versus continued zidovudine after the diagnosis of AIDS.: J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Aug 15;12(5):462-9. Unique Identifier : AIDSLINE MED/96335107; Vella S; Floridia M; Dally LG; Tomino C; Fragola V; Weimer LE; Milazzo F; Mazzotta F; Moroni M; Pastore G; Scalise G; Sinicco A; Ortona L; De Rienzo B; Dianzani F; Laboratory of Virology, Istituto Superiore di Sanita, Rome,; Italy.; Although the efficacy of switching from zidovudine ( AZT ) to didanosine (ddI) has already been evaluated in controlled studies, prior investigations were not specifically designed to evaluate this issue in patients with acquired immune deficiency syndr
Prophylaxis with nystatin pastilles for HIV-associated oral candidiasis.: J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Aug 15;12(5):470-6. Unique Identifier : AIDSLINE MED/96335108; MacPhail LA; Hilton JF; Dodd CL; Greenspan D; Department of Stomatology, University of California at San; Francisco, USA.; To determine whether daily use of nystatin pastilles can prevent initial outbreak or recurrence of oral candidiasis in HIV-infected patients and to identify factors associated with outbreaks during 20-week follow-up, a randomized, double-blind, placebo-controlled clinical trial was conducted. Subjects were 128 HIV-inf
Dapsone- and primaquine-induced methemoglobinemia in HIV-infected individuals.: J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Aug 15;12(5):477-81. Unique Identifier : AIDSLINE MED/96335109; Sin DD; Shafran SD; Department of Medicine, University of Alberta, Edmonton, Canada.; Clinically significant methemoglobinemia can develop as a result of medications. Although dapsone and primaquine are known to produce methemoglobinemia in susceptible individuals, methemoglobinemia has been reported only rarely in the human immunodeficiency virus (HIV) population. We describe five cases of methemoglob
Predictive value for survival of soluble tumor necrosis factor receptors p55 and p75 during zidovudine-containing treatment in symptomatic human immunodeficiency virus type 1 infection.: J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Aug 15;12(5):482-8. Unique Identifier : AIDSLINE MED/96335110; Frissen PH; Weverling GJ; Endert E; Jansen J; Sauerwein HP; Lange JM; Department of Internal Medicine, Onze Lieve Vrouwe Gasthuis,; Amsterdam, The Netherlands.; Previous studies of asymptomatic human immunodeficiency virus (HIV) infection have shown that serum levels of soluble tumor necrosis factor receptors (sTNFR) are good predictors of disease progression and clinical outcome during zidovudine (ZDV) therapy. The present study of symptomatic HIV infection was designed to e
Menstrual function in human immunodeficiency virus-infected women without acquired immunodeficiency syndrome.: J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Aug 15;12(5):489-94. Unique Identifier : AIDSLINE MED/96335111; Chirgwin KD; Feldman J; Muneyyirci-Delale O; Landesman S; Minkoff H; Department of Medicine, State University of New York, Health; Science Center at Brooklyn 11203, USA.; To assess whether HIV infection is associated with menstrual abnormalities in HIV-infected women without AIDS, we evaluated 248 premenopausal HIV-infected women without AIDS and 82 HIV-negative women. Detailed medical, drug use, and menstrual histories (using menstrual calendars) were obtained. Complete physical and p
Measuring HIV-1 incidence in northern Thailand: prospective cohort results and estimates based on early diagnostic tests.: J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Aug 15;12(5):495-9. Unique Identifier : AIDSLINE MED/96335112; Beyrer C; Brookmeyer R; Natpratan C; Kunawararak P; Niraroot V; Palapunya P; Khamboonruang C; Celentano DD; Nelson KE; Johns Hopkins University, USA.; Measuring the incidence of the human immunodeficiency virus (HIV) is of vital importance but can be difficult and costly. We compared HIV-1 incidence measured directly from prospective cohort studies with rates derived from a method using the prevalence of HIV-1 antibody-negative, p24-antigen-positive individuals. Mal
Determinants of HIV infection among female commercial sex workers in northeastern Thailand: results from a longitudinal study.: J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Aug 15;12(5):500-7. Unique Identifier : AIDSLINE MED/96335113; Ungchusak K; Rehle T; Thammapornpilap P; Spiegelman D; Brinkmann U; Siraprapasiri T; Division of Epidemiology, Ministry of Public Health, Nonthaburi,; Thailand.; Our objective was to estimate HIV seroconversion rates among commercial sex workers (CSWs) between 1990 and 1991 and to identify the behavioral, demographic, and reproductive determinants of these rates. This study has a prospective (n = 240 with 15 cases) and a cross-sectional component (n = 271 with 34 cases). In No
Hospitalization of patients infected with active TB in New York State, 1987-1992: the effect of the HIV epidemic.: J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Aug 15;12(5):508-13. Unique Identifier : AIDSLINE MED/96335114; Kaufman G; Han Y; Agins BD; New York State Department of Health, AIDS Institute, New York; 10001, USA.; Hospital discharge records were used to study the relationship between human immunodeficiency virus (HIV) epidemic and hospitalized patients with tuberculosis in New York State from 1987 through 1992. The discharges of patients coinfected with HIV and tuberculosis increased by 270%, rising from 1,573 in 1987 to 5,825
Weight loss associated with HIV seroconversion among injection-drug users.: J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Aug 15;12(5):514-8. Unique Identifier : AIDSLINE MED/96335115; Marmor M; Titus S; Harrison C; Cord-Cruz EA; Shore RE; Vogler M; Krasinski K; Mildvan D; Des Jarlais DC; Department of Environmental Medicine, New York University School; of Medicine, New York 10010-2598, USA.; To describe symptoms associated with human immunodeficiency virus (HIV) seroconversion, we studied a cohort of 366 injection-drug users (IDUs) with a study design that included recall every 3 months to collect symptom histories using a structured questionnaire. Eleven HIV seroconversions were observed in 621.5 person
Human T-cell lymphotropic virus type I infection in Barbados: results of a 20-year follow-up study.: J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Aug 15;12(5):519-22. Unique Identifier : AIDSLINE MED/96335116; Rabkin CS; Corbin DO; Felton S; Barker H; Davison D; Dearden C; Blattner WA; Evans AS; Viral Epidemiology Branch, National Cancer Institute, Bethesda,; Maryland 20852, USA.; Forty-one human T-cell lymphotropic virus type I (HTLV-1)-seropositive individuals were identified among 1,012 subjects with stored serum samples from a health and seroepidemiological survey conducted in Barbados in 1972. These 41 subjects plus 79 HTLV-1 seronegative household me
Safety and feasibility of harvesting cells for adoptive immunotherapy from patients with asymptomatic HIV infection [letter]: J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Aug 15;12(5):523-4. Unique Identifier : AIDSLINE MED/96335117; Trickett A; Dwyer J; Tedla N; Lam-Po-Tang R
HTLV-I/II survey on hemodialysis patients in Buenos Aires [letter]: J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Aug 15;12(5):525-6. Unique Identifier : AIDSLINE MED/96335118; DeVito C; Pampuro S; Del Pino N; Martinez Peralta L; Libonatti O
Specificity of HTLV antibody enzyme immunoassay [letter]: J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Aug 15;12(5):526-7. Unique Identifier : AIDSLINE MED/96335119; Ferreira Junior OC; Vaz RS; Carvalho MB; Hamerschlak N; Ferreira MM; Novoa P
Reactivity of Argentine serum samples against synthetic V3-based HIV-1 peptides [letter]: J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Aug 15;12(5):527-8. Unique Identifier : AIDSLINE GENBANK/L16609; Pampuro SE; Calarota SA; Marquina SA; Rabinovich RD; Libonatti OV
Viral/bacterial vaccination rates in HIV-infected patients [letter]: J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Aug 15;12(5):528-9. Unique Identifier : AIDSLINE MED/96335121; Bavry AA; Ahmed OI
Presence of human T-cell lymphotropic virus types I and II infections in Honduras [letter]: J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Aug 15;12(5):529-30. Unique Identifier : AIDSLINE MED/96335122; Vallejo A; Dubon JM; Garcia-Saiz A
The spectrum of non-AIDS-defining neoplastic disease in HIV infection.: J Investig Med. 1996 Jun;44(5):205-15. Unique Identifier : AIDSLINE MED/96321540; Remick SC; Division of Medical Hematology, Albany Medical College, NY 12208,; USA.
Immunological memory induced by genetically transduced tumor cells.: Ann Surg Oncol. 1996 May;3(3):247-54. Unique Identifier : AIDSLINE MED/96292643; Dar MM; Abdel-Wahab Z; Vervaert CE; Darrow T; Barber J; Seigler HF; Department of Surgery, Duke University Medical Center, Durham,; North Carolina 27710, USA.; BACKGROUND: Recent studies have demonstrated the usefulness of gene-modified tumor cells for immunotherapy. Using the tumorigenic murine fibrosarcoma, MCA 106, we investigated the effects of localized interferon-gamma (IFNg) secretion on tumorigenicity and on long-term memory. METHODS: The murine IFNg (MuIFNg) gene wa
Perspectives for the control of tuberculosis.: Ther Immunol. 1995 Apr;2(2):105-13. Unique Identifier : AIDSLINE MED/96290167; Rosen H; Horn D; Shaw A; Merck Research Laboratories, Rahway, NJ 07065 USA.; The control of tuberculosis has become more elusive with the increased incidence of HIV, and the continued selection of multidrug-resistant organisms. The intracellular pathogenesis of, and host-response to Mycobacterium tuberculosis present challenges to both classical chemotherapeutic and vaccination approaches, wit
Cambodia--daring traditional birth attendants to change tradition.: Midwives. 1996 Apr;109(1299):96-8. Unique Identifier : AIDSLINE MED/96361045; Cooke J
Non-typhoidal Salmonella bacteraemia: clinical features and risk factors.: Trop Med Int Health. 1996 Aug;1(4):443-8. Unique Identifier : AIDSLINE MED/96343956; Thamlikitkul V; Dhiraputra C; Paisarnsinsup T; Chareandee C; Department of Medicine, Faculty of Medicine, Siriraj Hospital,; Bangkok, Thailand.; A case control study was conducted to determine the risk factors of non-typhoidal Salmonella bacteraemia. Eighty adult patients with non-typhoidal Salmonella bacteraemia admitted to Siriraj Hospital from January to December 1993 served as the cases. The controls comprised 3 groups: group 1, 80 adult in-patients with E
Specific cleavage of target RNAs from HIV-1 with 5' half tRNA by mammalian tRNA 3' processing endoribonuclease.: RNA. 1996 Jun;2(6):523-4. Unique Identifier : AIDSLINE MED/96338261; Nashimoto M; Life Science Research Laboratory, Japan Tobacco Inc., Yokohama,; Kanagawa, Japan.; Mammalian tRNA 3 processing endoribonuclease (3 tRNase) can be converted to an RNA cutter that recognizes four bases, with about a 65-nt 3 -truncated tRNA(Arg) or tRNA(Ala). The 3 -truncated tRNA recognizes the target RNA via four base pairings between the 5 terminal sequence and a sequence 1-nt upstream of the clea
Infection control procedures--who should decide what cannot be used?: J Can Dent Assoc. 1996 Jun;62(6):471-3. Unique Identifier : AIDSLINE MED/96293030; Christensen RP; Clinical Research Associates, Provo, UT 84604, USA.
The law and ethics regarding infection control in treating HIV-positive patients [editorial]: J Can Dent Assoc. 1996 Jun;62(6):475. Unique Identifier : AIDSLINE MED/96293031; Graham PE; Harel-Raviv M
Continuing investigation and controversy regarding risk of transmission of infection via dental handpieces.: J Can Dent Assoc. 1996 Jun;62(6):485-91. Unique Identifier : AIDSLINE MED/96293032; Epstein JB; Rea G; Sherlock CH; Mathias RG; Department of Dentistry, Vancouver Hospital and Health Sciences; Centre, B.C., Canada.; Current epidemiologic evidence indicates that infectious diseases, specifically blood-borne pathogens such as hepatitis B, hepatitis C and HIV, are not transmitted from patient to patient via dental instruments. However, ongoing laboratory investigations suggest that potential pathogens may be retained within dental h
Teaching symptom management of HIV/AIDS using algorithms.: Cancer Nurs. 1996 Aug;19(4):263-8. Unique Identifier : AIDSLINE MED/96333980; Lietzau J; National Cancer Institute, National Institutes of Health,; Bethesda, MD 20892, USA.; Management of patients infected with the human immunodeficiency virus (HIV) or with acquired immunodeficiency syndrome (AIDS) presents a complex set of challenges to the health-care professional, especially in the area of patient education. Lack of resources, time constraints, and/or patients willingness to learn abo
[Effect of acupuncture on the regulation of cell-mediated immunity in the patients with malignant tumors]: Chen Tzu Yen Chiu. 1995;20(3):67-71. Unique Identifier : AIDSLINE MED/96333711; Wu B; In order to investigate the role of acupuncture in the regulation of cellular immune function, we observed acupuncture therapy affecting the levels of T lymphocytes subgroup (CD3+, CD4+, CD8+), soluble interleukin-2 receptor (SIL-2R) and beta-endorphin (beta-EP) in the peripheral blood of patients with malignant tumor
Protease inhibitors: promising new weapons against HIV.: Cleve Clin J Med. 1996 Jul-Aug;63(4):204-8. Unique Identifier : AIDSLINE MED/96334016; Isada CM
Treatment of cervix condylomata with alpha-IFN leucocytar.: Clin Exp Obstet Gynecol. 1995;22(4):326-9. Unique Identifier : AIDSLINE MED/96114160; Zarcone R; Bellini P; Cardone G; Cardone A; Department of Obstetrics and Gynecology, Second University of; Naples, Italy.; The main viruses responsible for condyloma, a venereal disease, are the HPV 16 and 11. The stages of HPV infection are under the control of the immunitary system, which is inhibited by the virus itself. For this reason, the therapy of cervical condylomatosis is, at present, based on the use of interferon. The purpose
[Clinico-radiological correlations in pulmonary pathology caused by immunosuppression]: Clin Ter. 1996 Jan-Feb;147(1-2):25-36. Unique Identifier : AIDSLINE MED/96298471; Sergiacomi GL; Giuliani V; Cerqua C; Simonetti G; Ospedale S. Eugenio, Universita degli Studi di Roma Tor Vergata.; Lung is the most involved site by infective manifestations in immunodepressed patients. In these patients the variability of pathogenic and opportunistic agents is expressed in the lungs with interstitial and alveolar changes, which are not pathognomonic. CT is the appropriate method to study lung parenchyma. CT by me
Epidemiology of anti-human T-cell leukemia virus type I antibody and characteristics of adult T-cell leukemia in China.: Chin Med J (Engl). 1995 Dec;108(12):902-6. Unique Identifier : AIDSLINE MED/96331381; Zhuo J; Yang T; Zeng Y; Lu L; Institute of Hematology, Chinese Academy of Medical Sciences,; Peking Union Medical College, Tianjin.; We analyzed the data from seroepidemiologic survey of anti-HTLV-I serum antibody (HTLV-1 Ab) and 16 adult cases of T-cell leukemia (ATL) in China (1984-1994). The results showed that the positive rate of HTLV-I Ab of the population of China was 0.54%, the birth or residence places o
T cells and cytokines in intracellular bacterial infections: experiences with Mycobacterium bovis BCG.: Ciba Found Symp. 1995;195:123-32; discussion 132-6. Unique Identifier : AIDSLINE MED/96285770; Kaufmann SH; Ladel CH; Flesch IE; Department of Immunology, University of Ulm, Germany.; Intracellular bacteria reside in mononuclear phagocytes, and protective immunity is dominated by T lymphocytes. Mycobacterium bovis bacillus Calmette-Guein (BCG) infection of mice represents an excellent model for studying immune mechanisms involved in defence against persistent intracellular bacteria that cause chron
Cytokines in immune regulation/pathogenesis in HIV infection.: Ciba Found Symp. 1995;195:142-7; discussion 147-53. Unique Identifier : AIDSLINE MED/96285771; Shearer GM; Clerici M; Sarin A; Berzofsky JA; Henkart PA; National Cancer Institute, National Institutes of Health,; Bethesda, MD 20892, USA.; Two hallmarks of immunopathogenesis in the progression of HIV-infected individuals to AIDS are the loss of T helper (Th) cell function in response to antigens and the critical reduction in CD4+ T cell numbers. It is probable that these two phenomena are related. We observed that: (1) the failure to detect antigen-stim
Signalling events in the anergy induction of T helper 1 cells.: Ciba Found Symp. 1995;195:189-96; discussion 196-202. Unique Identifier : AIDSLINE MED/96285774; Sloan-Lancaster J; Allen PM; Department of Pathology, Washington University School of; Medicine, St. Louis, MO 63110-1093, USA.; T cells can interact productively with altered peptide ligands (APLs) resulting in different phenotypic outcomes. Stimulation of T helper 1 cells with an APL on live antigen-presenting cells results in the induction of anergy. We investigated the intracellular signalling events involved in generating this anergy by co
Reversal of polarized T helper 1 and T helper 2 cell populations in murine leishmaniasis.: Ciba Found Symp. 1995;195:20-5; discussion 25-33. Unique Identifier : AIDSLINE MED/96285764; Coffman RL; Correa-Oliviera R; Mocci S; Department of Immunology, DNAX Research Institute of Molecular; and Cellular Biology, Palo Alto, CA 94304-1104, USA.; T helper 1 (Th1) and Th2 cells are the major subsets of fully differentiated CD4+ T cells in the mouse. The spectrum of cytokines characteristic of each subset determines the distinctive regulatory and effector functions mediated by each subset. We have used the murine model of Leishmania major infection to study the
The two faces of interleukin 12: a pro-inflammatory cytokine and a key immunoregulatory molecule produced by antigen-presenting cells.: Ciba Found Symp. 1995;195:203-14; discussion 214-20. Unique Identifier : AIDSLINE MED/96285775; Trinchieri G; Wistar Institute for Anatomy and Biology, Philadelphia, PA 19104,; USA.; Interleukin 12 (IL-12) is produced by phagocytic cells, antigen-presenting cells and B lymphocytes in response to bacteria or intracellular parasites. IL-12 acts on T and natural killer (NK) cells inducing: production of cytokines, particularly gamma-interferon (IFN-gamma); proliferation; and enhancement of cell-media
Differentiation of subsets of CD4+ and CD8+ T cells.: Ciba Found Symp. 1995;195:42-50; discussion 50-4. Unique Identifier : AIDSLINE MED/96285765; Mosmann TR; Sad S; Krishnan L; Wegmann TG; Guilbert LJ; Belosevic M; Department of Immunology, University of Alberta, Edmonton,; Canada.; Our knowledge of the cytokine secretion patterns of T cells and other cells is clearly becoming more complex. The T helper 1 (Th1) and Th2 patterns may represent the extremes of a spectrum of cytokine regulatory patterns controlled by several cell types. CD8+ T cells can also secrete either Th1-like or Th2-like cytoki
Role for CD30 antigen in human T helper 2-type responses.: Ciba Found Symp. 1995;195:55-62; discussion 62-7. Unique Identifier : AIDSLINE MED/96285766; Romagnani S; Division of Clinical Immunology and Allergy, Institute of; Clinical Medicine 3, University of Florence, Italy.; Human T helper 1 (Th1) cells develop preferentially during infections by intracellular parasites and trigger phagocyte-mediated host defence. In contrast, human Th2 cells are responsible for phagocyte-independent host response, and they predominate during helminthic infestations and in atopic humans in response to com
Regulation of T lymphocyte subsets.: Ciba Found Symp. 1995;195:68-80; discussion 80-5. Unique Identifier : AIDSLINE MED/96285767; Fitch FW; Stack R; Fields P; Lancki DW; Cronin DC; Department of Pathology, University of Chicago, IL 60637, USA.; Patterns of cytokine secretion and functional differences distinguish T lymphocyte subsets. T lymphocyte subsets are also regulated differentially. Most established CD8+ lymphocyte clones secrete gamma-interferon (IFN-gamma) but not interleukin 2 ( IL-2 ) or IL-4. Using
Induction and regulation of host cell-mediated immunity by Toxoplasma gondii.: Ciba Found Symp. 1995;195:95-104; discussion 104-9. Unique Identifier : AIDSLINE MED/96285768; Sher A; Denkers EY; Gazzinelli RT; Laboratory of Parasitic Diseases, National Institute of Allergy; and Infectious Diseases, National Institutes of Health, Bethesda,; MD 20892, USA.; Toxoplasma gondii is a highly infectious intracellular parasite which, if left unchecked by the immune system, rapidly overwhelms its intermediate hosts, as illustrated by the pathogenesis of toxoplasmic encephalitis in patients with AIDS. In order to insure both its host s and consequently its own survival simultaneo
Prospective evaluation of a model of risk for HIV infection among injecting drug users.: Drug Alcohol Depend. 1995 Nov;40(1):63-71. Unique Identifier : AIDSLINE MED/96356402; Iguchi MY; Bux DA Jr; Kushner H; Lidz V; French JF; Platt JJ; Department of Psychiatry, Medical College of Pennsylvania,; Philadelphia 19102-1192, USA.; Data on 3016 out-of-treatment injecting drug users (IDUs) were analyzed in order to replicate findings from an earlier study on risk factors for HIV infection (Iguchi et al., 1992) and evaluate a model for estimating probability of infection. Logistic regression analyses yielded a set of risk factors highly consistent
[Consensus on the optimal HIV therapy. Consensus Conference on the Importance of Viral Load in the Therapy of HIV Infections, Langen, May 1996 (news)]: Dtsch Med Wochenschr. 1996 Jul 26;121(30):A10. Unique Identifier : AIDSLINE MED/96366707; Weismann H
[The significance of age in HIV-1 infection for the prognosis of the disease (news)]: Dtsch Med Wochenschr. 1996 Jul 26;121(30):A9. Unique Identifier : AIDSLINE MED/96366706; Morike EM
Activation of the IL-2 gene promoter by HTLV-I tax involves induction of NF-AT complexes bound to the CD28-responsive element.: EMBO J. 1996 Jul 15;15(14):3744-50. Unique Identifier : AIDSLINE MED/96312972; Good L; Maggirwar SB; Sun SC; Department of Microbiology and Immunology, Pennsylvania State; University College of Medicine, Hershey Medical Center, PA 17033,; USA.; The tax gene product of the type I human T-cell leukemia virus (HTLV-I) is a potent transcriptional activator of various growth-related cellular genes, including that encoding interleukin-2 ( IL-2 ). Tax activation of many of these target genes appears to be mediated by
Specificity of hammerhead ribozyme cleavage.: EMBO J. 1996 Jul 15;15(14):3751-7. Unique Identifier : AIDSLINE MED/96312973; Hertel KJ; Herschlag D; Uhlenbeck OC; Department of Chemistry and Biochemistry, University of Colorado,; Boulder 80309-0215, USA.; To be effective in gene inactivation, the hammerhead ribozyme must cleave a complementary RNA target without deleterious effects from cleaving non-target RNAs that contain mismatches and shorter stretches of complementarity. The specificity of hammerhead cleavage was evaluated using HH16, a well-characterized ribozyme
Percutaneous catheter drainage of breast abscesses.: Eur J Radiol. 1996 Feb;21(3):217-9. Unique Identifier : AIDSLINE MED/96260653; Berna JD; Garcia-Medina V; Madrigal M; Guirao J; Llerena J; Departmento de Radiologia del Hospital General, Facultad de; Medicina, Universidad de Murcia, Spain.; Experiences with ultrasonically guided percutaneous catheter drainage of breast abscesses (BA) are presented. The 12 cases were: 10 non-lactating women, one lactating women, and one HIV-positive man. The percutaneous procedure employed was successful in all cases. The mean duration of drainage was 5 days post-catheter
Neonatal and early life immune responses to various forms of vaccine antigens qualitatively differ from adult responses: predominance of a Th2-biased pattern which persists after adult boosting.: Eur J Immunol. 1996 Jul;26(7):1489-96. Unique Identifier : AIDSLINE MED/96305404; Barrios C; Brawand P; Berney M; Brandt C; Lambert PH; Siegrist CA; WHO Collaborating Centre for Neonatal Vaccinology, University of; Geneva, Switzerland.; Induction of neonatal immune responses to vaccine antigens is believed to be of limited efficacy because of immune immaturity and particular susceptibility to tolerogenic signals during this period of life. To characterize particular features of neonatal immune responses to vaccine antigens, we assessed the capacity o
Relationship between Th1/Th2 cytokine patterns and the arthritogenic response in collagen-induced arthritis.: Eur J Immunol. 1996 Jul;26(7):1511-8. Unique Identifier : AIDSLINE MED/96305407; Mauri C; Williams RO; Walmsley M; Feldmann M; Kennedy Institute of Rheumatology, Sunley Division, London, GB.; It is hypothesized that the balance of cytokines produced by Th1/Th2 subsets of T helper cells plays an important role in the development of autoimmune diseases. Murine collagen-induced arthritis (CIA) is an example of an autoimmune disease in which immunization with cartilage-derived type II collagen induces, firstly
Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response.: Eur J Immunol. 1996 Jul;26(7):1553-9. Unique Identifier : AIDSLINE MED/96305413; Mattner F; Magram J; Ferrante J; Launois P; Di Padova K; Behin R; Gately MK; Louis JA; Alber G; Department of Infectious Diseases, F. Hoffmann-La Roche AG,; Basel, Switzerland.; Mice with homologous disruption of the gene coding for either the p35 subunit or the p40 subunit of interleukin-12 (IL-12) and derived from a strain genetically resistant to infection with Leishmania major have been used to study further the role of this cytokine in resistance to infection and the differentiation of f
Accessory signaling by CD40 for T cell activation: induction of Th1 and Th2 cytokines and synergy with interleukin-12 for interferon-gamma production.: Eur J Immunol. 1996 Jul;26(7):1621-7. Unique Identifier : AIDSLINE MED/96305423; Peng X; Kasran A; Warmerdam PA; de Boer M; Ceuppens JL; Department of Pathophysiology, Catholic University of Leuven,; Belgium.; The interaction of CD40 ligand (CD40L) on activated T cells with CD40 on B cells, monocytes and dendritic cells is essential for humoral immunity and for up-regulation of antigen-presenting cell (APC) functions, as a result of signaling through CD40. There are also some indications that after interaction with CD40, CD
Permissive residues within the minimal epitopes of neutralizing monoclonal antibodies to the V3 loop of HIV-1.: Eur J Immunol. 1996 Jul;26(7):1634-40. Unique Identifier : AIDSLINE MED/96305425; Laisney IL; Benjamin H; Gefter M; Strosberg AD; Laboratoire d'Immuno-pharmacologie Moleculaire, Institut Cochin; de Genetique Moleculaire, Paris, France.; Neutralizing monoclonal antibodies (mAb) specific for the third variable (V3) domain of gp120, the HIV-1 surface envelope protein, are mainly isolate specific. We have studied the composition and the permissivity of the minimal epitopes interacting with two of these, the 110-A and 19.26.4 mAb, which are strictly LAI i
Interferon-gamma-inducing factor enhances T helper 1 cytokine production by stimulated human T cells: synergism with interleukin-12 for interferon-gamma production.: Eur J Immunol. 1996 Jul;26(7):1647-51. Unique Identifier : AIDSLINE MED/96305427; Micallef MJ; Ohtsuki T; Kohno K; Tanabe F; Ushio S; Namba M; Tanimoto T; Torigoe K; Fujii M; Ikeda M; Fukuda S; Kurimoto M; Fujisaki Institute, Hayashibara Biochemical Laboratories Inc.,; Okayama, Japan.; The novel cytokine interferon-gamma-inducing factor (IGIF) augments natural killer (NK) cell activity in cultures of human peripheral blood mononuclear cells (PBMC), similarly to the structurally unrelated cytokine interleukin (IL)-12. IGIF has been found to enhance the production of interferon-gamma (IFN-gamma) and g
A functionally significant allelic polymorphism in a T cell receptor V beta gene segment.: Eur J Immunol. 1996 Jul;26(7):1660-3. Unique Identifier : AIDSLINE MED/96305430; Vessey SJ; Bell JI; Jakobsen BK; Institute of Molecular Medicine, John Radcliffe Hospital, Oxford,; Great Britain.; The effect of an allelic polymorphism in the BV1S1 gene segment on recognition of major histocompatibility complex (MHC)-peptide complexes by a specific T cell receptor (TCR) was studied using RBL 2H3 cells transfected with TCR-CD3 zeta chimeric receptors. An HLA-A2-restricted human immunodeficiency virus (HIV) pol-sp
High-risk sexual behavior among young urban students.: Fam Plann Perspect. 1996 Mar-Apr;28(2):69-74. Unique Identifier : AIDSLINE MED/96261887; Barone C; Ickovics JR; Ayers TS; Katz SM; Voyce CK; Weissberg RP; Department of Psychology, Yale University, USA.; A substantial number of adolescents, including many as young as 11, engage in high-risk sexual behavior. In a 1992 survey of 2,248 urban students in grades 6, 8 and 10, 45% of respondents, including 28% of sixth graders, were sexually active; the majority of sexually experienced students had had two or more partners.
Condom availability in the schools: lessons from the courtroom.: Fam Plann Perspect. 1996 Mar-Apr;28(2):75-7. Unique Identifier : AIDSLINE MED/96261888; Mahler K
Risk factors for tuberculosis among HIV-infected patients in Switzerland. Swiss HIV Cohort Study.: Eur Respir J. 1996 Feb;9(2):279-83. Unique Identifier : AIDSLINE MED/96236709; Sudre P; Hirschel B; Toscani L; Ledergerber B; Rieder HL; Division of Infectious Diseases, University Hospital, Geneva,; Switzerland.; The aim of this study was to determine the risk factors associated with tuberculosis among human immunodeficiency virus (HIV)-infected persons living in Switzerland , a country with low prevalence of tuberculous infection. We performed a nested case-control study and logistic r
Characteristics of sputum smear-positive tuberculosis patients with and without HIV infection in a hospital in Zimbabwe.: Eur Respir J. 1996 Feb;9(2):284-7. Unique Identifier : AIDSLINE MED/96236710; Schoch OD; Rieder HL; Driefontein Tuberculosis Sanatorium, Mvuma, Zimbabwe.; Human immunodeficiency virus (HIV) infection has a large impact on tuberculosis in Africa. In this study, the prevalence of HIV infection in a population of hospitalized tuberculosis patients in Zimbabwe was determined and demographic characteristics, clinical signs and symptoms,
Evaluation of a western blot serum test for the diagnosis of Mycobacterium tuberculosis infection.: Eur Respir J. 1996 Feb;9(2):288-92. Unique Identifier : AIDSLINE MED/96236711; Rovatti E; Corradi MP; Amicosante M; Tartoni PL; Panini W; Ancora A; Cenci AM; Zucchi L; Monno L; Angarano G; Saltini C; Dipartimento di Scienze Medicine, Universita di Modena, Italy.; This study was designed to evaluate the possibility of monitoring Mycobacterium tuberculosis infection using a serological assay. A discriminant score comprising antigen fractions of 38, 28, 24 and 19 kDa, identified in western blots using the Mycobacterium bovis bacille Calmette-Guerin (BCG) A60 antigen complex was e
Kaposi's disease and sarcoidosis.: Eur Respir J. 1996 Feb;9(2):383-5. Unique Identifier : AIDSLINE MED/96236727; Corda L; Benerecetti D; Ungari M; Facchetti F; Radaeli E; Terza Divisione di Medicina Generale, Spedali Civili, Brescia,; Italy.; A human immunodeficiency virus (HIV) antibody-negative 65 year old woman was treated with corticosteroids for 7 yrs because of bilateral uveitis. One year after the beginning of corticosteroid treatment, erythematous skin lesions appeared on the legs. Eight years after the diagnosis of uveitis, gastric and bronchial b
Update on urticaria and angioedema (hives).: Allergy Proc. 1995 Nov-Dec;16(6):289-92. Unique Identifier : AIDSLINE MED/96359672; Fox RW; Division of Allergy and Immunology, University of South Florida; Health Sciences Center, Tampa, USA.; The update on urticaria involves new concepts on the pathogenesis and the treatment of severe hives that are unresponsive to conventional treatments. A newly described autoantibody IgG against IgE receptor has been identified in some severe chronic urticaria patients. Anti-inflammatory and immunomodulating agents are
[Coping with AIDS in a support group--an encounter with the health system]: Harefuah. 1996 Apr 15;130(8):521-3, 583. Unique Identifier : AIDSLINE MED/96316532; Weishut DJ; Israel AIDS Task Force, Tel Aviv.; We present the first documentation of a short-term support group for the HIV-infected and those with AIDS in Israel . The group enabled its members to cope with existential issues and with the psychological, social and medical hardships of these conditions, thus becoming an essentia
[Protease inhibitors are effective only on HIV-infected cells (news)]: Fortschr Med. 1996 May 30;114(15):12. Unique Identifier : AIDSLINE MED/96290879
[Safer trials of vaccine and gene therapy against HIV]: Hokkaido Igaku Zasshi. 1996 Jan;71(1):21-6. Unique Identifier : AIDSLINE MED/96317699; Ikuta K; Section of Serology, Hokkaido University, Sapporo, Japan.; HIV, the etiological agent of AIDS, induces depletion of CD4+T cells. Upon primary infection, there is an initial viremia that is followed rapidly by a cell-mediated immune response and apparent viral clearance. Thereafter, the persistence of low levels of HIV in the blood for years before the onset of the disease is
Tat mediates transcriptional activation of HIV-1 gene in vitro.: Indian J Biochem Biophys. 1995 Dec;32(6):351-5. Unique Identifier : AIDSLINE MED/96318749; West M; Hoover T; Kung H; Raziuddin; Biological Carcinogenesis and Development Program, Program; Resources Inc./DynCorp, National Cancer Institute, Frederick, MD; 21702, USA.; Gene expression of human immunodeficiency virus (HIV-1) is greatly enhanced by a viral transactivator, the Tat protein, which interacts with R region sequences of the HIV-1 long terminal repeat (LTR). There is no direct evidence to indicate transcriptional activation of HIV-1 by Tat. Using an in vitro transcription sy
Stimulation of human peripheral blood mononuclear cells with live Mycobacterium bovis BCG activates cytolytic CD8+ T cells in vitro.: Immunology. 1996 Mar;87(3):339-42. Unique Identifier : AIDSLINE MED/96247201; Turner J; Dockrell HM; Department of Clinical Sciences, London School of Hygiene and; Tropical Medicine, UK.; Experimental data have shown that Mycobacterium tuberculosis can survive within the host cell and in doing so may release secreted antigen into the endogenous antigen-processing pathway. If mycobacterial antigen can gain access to MHC class I molecules then CD8+ T cells may play a role in host defence against M. tuber
The method of deriving human T-cell clones alters the proportion of IL-10-producing cells.: Immunology. 1996 Mar;87(3):343-7. Unique Identifier : AIDSLINE MED/96247202; Cohen SB; Webb LM; Feldmann M; Kennedy Institute of Rheumatology, London, UK.; It is now well documented that the mode of primary stimulation in the mouse determines the ratio of Th1-, Th0- or Th2-type T cells obtained. In this paper we determine whether driving and cloning human peripheral blood mononuclear cells (PBMC) non-specifically with interleukin-2 (
Th1/Th2 cell dichotomy in acquired immunity to Bordetella pertussis: variables in the in vivo priming and in vitro cytokine detection techniques affect the classification of T-cell subsets as Th1, Th2 or Th0.: Immunology. 1996 Mar;87(3):372-80. Unique Identifier : AIDSLINE MED/96247206; Barnard A; Mahon BP; Watkins J; Redhead K; Mills KH; Department of Biology, St Patrick's College, Maynooth, Co.; Kildare, Ireland.; In studies of the mechanism of immunity to Bordetella pertussis in a murine respiratory infection model, we have previously demonstrated that natural infection of immunization with a whole cell vaccine induces a potent protective immune response, which is mediated by T-helper type-1 (Th1) cells. In contrast an acellul
Role of polymorphic residues of human leucocyte antigen-DR molecules on the binding of human immunodeficiency virus peptides.: Immunology. 1996 Mar;87(3):414-20. Unique Identifier : AIDSLINE MED/96247212; Jurcevic S; Praud C; Coppin HL; Bertrand A; Ricard S; Thomsen M; Lakhdar-Ghazal F; De Preval C; INSERM Unite 395, Universite Paul Sabatier, Toulouse, France.; A study was made of the binding properties of 96 human immunodeficiency virus peptides to human leucocyte antigen (HLA)-DR1 and HLA-DR103 molecules, which differ by three amino acids at positions 67, 70 and 71 in the beta chains. The affinity of the peptides was characterized by their inhibitory concentrations in comp
Parallel pattern of expression of CD43 and of LFA-1 on the CD45RA+ (naive) and CD45RO+ (memory) subsets of human CD4+ and CD8+ cells. Correlation with the aggregative response of the cells to CD43 monoclonal antibodies.: Immunology. 1996 Mar;87(3):439-46. Unique Identifier : AIDSLINE MED/96247216; Youseffi-Etemad R; Axelsson B; Department of Immunology, Stockholm University, Sweden.; Human peripheral blood T cells form large aggregates when cultured in the presence of antibodies to the highly sialylated protein CD43. About 25% of the cells in such cultures do not aggregate, however, although virtually all T cells express CD43. To find out if these cells constitute a distinct subpopulation of T cel
Retrovirus-elicited interleukin-12 and tumour necrosis factor-alpha as inducers of interferon-gamma-mediated pathology in mouse AIDS.: Immunology. 1996 Mar;87(3):467-74. Unique Identifier : AIDSLINE MED/96247220; Giese NA; Gazzinelli RT; Actor JK; Morawetz RA; Sarzotti M; Morse HC 3rd; Laboratory of Immunopathology, National Institute of Allergy &; Infectious Diseases, National Institutes of Health, Bethesda, MD; 20892-0760, USA.; Spleen cells from mice resistant or sensitive to mouse acquired immune deficiency syndrome (MAIDS) were examined for cytokine mRNA. In MAIDS-resistant BALB/c mice, cytokine transcripts peaked at 1 week after infection with Type 1 cytokines [interleukin-2 ( IL-2 ), tumour
Structural abnormality of 1q in an AIDS-related body-cavity-based lymphoma [letter]: Int J Cancer. 1996 Aug 7;67(4):588-90. Unique Identifier : AIDSLINE MED/96323324; Polito P; Canzonieri V; Cilia AM; Gloghini A; Gaidano G; Carbone A
Verbal autopsy as a tool for diagnosing HIV-related adult deaths in rural Uganda.: Int J Epidemiol. 1996 Jun;25(3):679-84. Unique Identifier : AIDSLINE MED/96324882; Kamali A; Wagner HU; Nakiyingi J; Sabiiti I; Kengeya-Kayondo JF; Mulder DW; Medical Research council (UK) Programme on AIDS in Uganda, Uganda; Virus Research Institute, PO Box 49, Entebbe, Uganda.; BACKGROUND. In general, information on the causes of adult deaths in developing countries is scarce. More specifically, relatively little is known about the effect of HIV-1 associated disease on adult mortality in general populations. In this study we have used a verbal autopsy technique to ascertain whether adult dea
Guide to preventing HIV transmission in health facilities [news]: Int Nurs Rev. 1996 Mar-Apr;43(2):41. Unique Identifier : AIDSLINE MED/96272022
[Reactive arthritis]: Hautarzt. 1996 Jun;47(6):479-87; quiz 485-6. Unique Identifier : AIDSLINE MED/96293945; Hitzelhammer J; Smolen J; Zentrum fur Diagnostik und Therapie, Medizinische Abteilung,; Krankenhaus Lainz, Wien.
Purification of the pets factor. A nuclear protein that binds to the inducible TG-rich element of the human immunodeficiency virus type 2 enhancer.: J Biol Chem. 1996 Aug 9;271(32):19599-605. Unique Identifier : AIDSLINE MED/96325081; Fu GK; Markovitz DM; Department of Internal Medicine, Division of Infectious Diseases,; University of Michigan Medical Center, Ann Arbor, Michigan; 48109-0642, USA.; The peri-ets (pets) site is a TG-rich element found immediately adjacent to two binding sites for the ets family member Elf-1 in the human immunodeficiency virus type 2 (HIV-2) enhancer. Enhancer activation in response to T cell stimulation by phorbol myristate acetate, phytohemagglutinin, soluble or cross-linked anti
Sleep in men and women infected with human immunodeficiency virus.: Holist Nurs Pract. 1996 Jul;10(4):33-43. Unique Identifier : AIDSLINE MED/96360909; Cohen FL; Ferrans CE; Vizgirda V; Kunkle V; Cloninger L; Little is known about sleep problems in persons with human immunodeficiency virus (HIV) infection. The article reports a study that assessed quantitative and qualitative aspects of sleep in a group of men and women with HIV infection and examined sleep parameters in regard to the degree of immune function. The conveni
From the wings of night: dream work with people who have acquired immunodeficiency syndrome.: Holist Nurs Pract. 1996 Jul;10(4):69-87. Unique Identifier : AIDSLINE MED/96360913; Muff J; Nurses who work with seriously ill and dying patients are engaged in helping them live fully until they die. Most theories of death and dying deal with conscious activities only. Yet many people find relief form the fear and loneliness of life-threatening illness if given the opportunity to express their totality, mea
Calcitonin gene-related peptide enhances apoptosis of thymocytes.: J Neuroimmunol. 1996 Jul;67(2):103-9. Unique Identifier : AIDSLINE MED/96337177; Sakuta H; Inaba K; Muramatsu S; Department of Zoology, Faculty of Science, Kyoto University,; Japan.; The effect of calcitonin gene-related peptide (CGRP), a neuropeptide, on the apoptosis of murine thymocytes was investigated. CGRP enhanced apoptosis of thymocytes beyond the spontaneous level at concentrations of 10(-11) M or higher, and the effect attained a plateau at 10(-9) M, mainly by stimulating cAMP formation.
Recombinant interferon-beta blocks proliferation but enhances interleukin-10 secretion by activated human T-cells.: J Neuroimmunol. 1996 Jul;67(2):111-8. Unique Identifier : AIDSLINE MED/96337178; Rep MH; Hintzen RQ; Polman CH; van Lier RA; Department of Clinical Viro-Immunology, Central Laboratory, The; Netherlands Red Cross Blood Transfusion Service, Amsterdam, The; Netherlands.; Results from recent clinical trials have indicated that recombinant interferon-beta (rIFN-beta) is a promising drug for the treatment of Multiple Sclerosis (MS), a disease of supposed autoimmune etiology. To gain insight into the immunoregulatory properties of this cytokine, we analyzed effects of interferon-beta (IFN
Attitudes about condoms and condom use among college students.: J Am Coll Health. 1996 May;44(6):243-9. Unique Identifier : AIDSLINE MED/96318294; Beckman LJ; Harvey SM; Tiersky LA; California School of Professional Psychology, Los Angeles, USA.; The authors assessed the relationships of ethnicity, gender, previous condom use, and intended condom use to perceived attributes of the condom and the contraceptive pill in a multiethnic sample of 197 college students. Factors that appeared to underlie attitudes toward the condom and the Pill included prevention of h
College women's sexuality in an era of AIDS.: J Am Coll Health. 1996 May;44(6):252-61. Unique Identifier : AIDSLINE MED/96318295; Uddin M; Stanford University.; The author surveyed 238 heterosexual undergraduate women enrolled in a California university in 1993 to determine levels of perceived self-efficacy to engage in safer sexual behavior. She predicted that perceived self-efficacy levels would be related to dimensions of sexuality that may play a role in decreasing women
AIDS awareness among nursing students of Delhi.: J Commun Dis. 1996 Mar;28(1):20-7. Unique Identifier : AIDSLINE MED/96240036; Kumar A; Lal P; Walia M; Arora R; Gulati N; Department of Preventive and Social Medicine, Maulana Azad; Medical College, New Delhi.; A total of 233 students of nursing school affiliated to a major hospital of Delhi were surveyed anonymously employing a predesigned, pretested and self-administered questionnaire. Although, 78.6 per cent students knew that AIDS stands for Acquired Immuno-deficiency Syndrome, 15.5 per cent students were unaware of the
Low prevalence of human immunodeficiency virus type-1 (HIV-1) infection in population attending a major hospital in New Delhi, India.: J Commun Dis. 1996 Mar;28(1):45-8. Unique Identifier : AIDSLINE MED/96240040; Aggarwal RK; Chattopadhya D; Kumari S; AIDS Reference Laboratory Division of Microbiology National; Institute of Communicable Diseases Delhi, India.; During 4 year period between April 1990 and March 1994, 4120 specimens from the patients attending out patient departments of Medical, Surgical and Antenatal units of a major city hospital were tested for HIV infection as a part of an on-going sentinel surveillance programme. In addition, 1440 specimens from the patie
Beta-chemokine inhibition of monocytotropic HIV-1 infection. Interference with a postbinding fusion step.: J Immunol. 1996 Aug 15;157(4):1329-32. Unique Identifier : AIDSLINE MED/96322715; Oravecz T; Pall M; Norcross MA; Division of Hematologic Products, Bethesda, MD 20892, USA.; The beta-chemokines RANTES, MIP-1 alpha, and MIP-1 beta have potent suppressive effects on HIV-1 infection resulting from an early postbinding block in virus fusion and entry. Inhibition was observed only with monocytotropic isolates and mapped to the V3 region of the HIV-1 envelope. RANTES did not inhibit virus expre
Naive murine neonatal T cells undergo apoptosis in response to primary stimulation.: J Immunol. 1996 Aug 15;157(4):1343-9. Unique Identifier : AIDSLINE MED/96322718; Adkins B; Chun K; Hamilton K; Nassiri M; Department of Pathology, University of Miami Medical School, FL; 33136, USA.; The cellular mechanisms controlling deficient immune responses in newborn animals are not well understood. Our earlier studies showed that developmental regulation of Th cell activity may be one of the major causes of immunodeficiency in neonatal animals. Naive murine neonatal T cells showed poor Th1 activity but robu
A direct role for IFN-gamma in regulation of Th1 cell development.: J Immunol. 1996 Aug 15;157(4):1350-8. Unique Identifier : AIDSLINE MED/96322719; Bradley LM; Dalton DK; Croft M; Department of Biology, University of California, La Jolla 92093,; USA.; IL-12 has been identified as a major cytokine influencing the differentiation of CD4 cells to a Th1 phenotype, whereas a role for IFN-gamma is controversial. We investigated the interrelationship between IL-12 and IFN-gamma in promoting Th1 responses using naive CD4 cells reactive with pigeon cytochrome c from TCR tra
Phorbol ester and calcium ionophore can replace TCR signals that induce positive selection of CD4 T cells.: J Immunol. 1996 Aug 15;157(4):1508-13. Unique Identifier : AIDSLINE MED/96322737; Takahama Y; Nakauchi H; Department of Immunology, University of Tsukuba, Japan.; Positive selection of immature thymocytes is a developmental process in which TCR ligation by low avidity interaction induces the generation of mature T cells. However, biochemical signals that can induce positive selection have been unclear. By using TCR-alpha beta- mutant thymus cultures, the present study shows tha
Th1-associated immune responses to beta-galactosidase expressed by a replication-defective herpes simplex virus.: J Immunol. 1996 Aug 15;157(4):1598-604. Unique Identifier : AIDSLINE MED/96322749; Brubaker JO; Thompson CM; Morrison LA; Knipe DM; Siber GR; Finberg RW; Laboratory of Infectious Diseases, Dana-Farber Cancer Institute,; Boston, MA 02115, USA.; The immunogenic properties of a replication-defective herpes simplex virus HD-2, containing the Escherichia coli lacZ gene under control of the HSV ICP8 early gene promoter were studied in BALB/c mice. Experiments were designed to determine if the HD-2 virus preferentially stimulated either Th1- or Th2-associated immu
Participation of lymphocyte subpopulations in the pathogenesis of experimental murine cerebral malaria.: J Immunol. 1996 Aug 15;157(4):1620-4. Unique Identifier : AIDSLINE MED/96322752; Yanez DM; Manning DD; Cooley AJ; Weidanz WP; van der Heyde HC; Department of Medical Microbiology and Immunology, University of; Wisconsin, Madison 53706, USA.; We determined the requirement for selected lymphocyte subsets and cytokines in the pathogenesis of experimental murine cerebral malaria (CM) by using gene-targeted knockout and mAb-suppressed mice. Plasmodium berghei ANKA infection induced CM in A 0/0 mice, which lack expression of surface MHC class II glycoproteins a
Induction of autoimmunity in the absence of CD28 costimulation.: J Immunol. 1996 Aug 15;157(4):1752-7. Unique Identifier : AIDSLINE MED/96322770; Bachmaier K; Pummerer C; Shahinian A; Ionescu J; Neu N; Mak TW; Penninger JM; Amgen Institute, Ontario Cancer Institute, Toronto, Canada.; Ag-specific activation of T lymphocytes requires two signals, one by the TCR and a second by costimulatory molecules. In a CD4+ T helper cell-dependent experimental autoimmune myocarditis model, we provide genetic evidence that cardiac myosin-induced autoimmune myocarditis and the production of IgG auto-Abs is depende
Susceptibility of HIV-1 plasma virus to complement-mediated lysis. Evidence for a role in clearance of virus in vivo.: J Immunol. 1996 Aug 15;157(4):1791-8. Unique Identifier : AIDSLINE MED/96322774; Sullivan BL; Knopoff EJ; Saifuddin M; Takefman DM; Saarloos MN; Sha BE; Spear GT; Department of Immunology/Microbiology, Rush University, Chicago,; IL 60612, USA.; This study was undertaken to directly assess the susceptibility of HIV-1 plasma virus to C-mediated lysis. Plasma from HIV-infected individuals was collected and ultracentrifuged over 20% sucrose to isolate virions from plasma components including anticoagulants, which inhibit C activity. Treatment with C alone in the
Assessment of latex indirect agglutination test (Toxolatex Fumouze) for the detection of Toxoplasma specific antibodies in human sera in Turkey.: J Egypt Soc Parasitol. 1996 Aug;26(2):367-74. Unique Identifier : AIDSLINE MED/96321596; Guruz AY; Ok UZ; Korkmaz M; Department of Parasitology, Faculties of Medicine, Ege University; Bornova-Izmir, Turkey.; Sera from 50 patients were examined with conventional ELISA, IFA and Toxolatex Fumouze. Out of 50 specimens only 3 false positive cases were detected with Toxolatex Fumouze as compared with the results of ELISA & IFA tests. Toxolatex Fumouze represents a rapid, highly sensitive and specific technique for screening
Mucormycosis of the upper limb.: J Hand Surg [Br]. 1996 Apr;21(2):261-2. Unique Identifier : AIDSLINE MED/96303107; al-Qattan MM; al Mazrou AM; Department of Plastic Surgery, King Saud University, Riyadh,; Saudi Arabia.; A rare case of mucormycosis of the upper limb in a patient with AIDS is described. The pathophysiology and natural history of the disease are described along with a classification of its clinical stages.
The HIV experience in Florida.: J Fla Med Assoc. 1996 Jun-Jul;83(6):401-5. Unique Identifier : AIDSLINE MED/96280325; Nelson RP Jr; University of South Florida, All Children's Hospital, St.; Petersburg, USA.
Molecular biology of the feline immunodeficiency virus auxiliary genes.: J Gen Virol. 1996 Aug;77 ( Pt 8):1611-21. Unique Identifier : AIDSLINE MED/96332497; Tomonaga K; Mikami T; Department of Veterinary Microbiology, Faculty of Agriculture,; University of Tokyo, Japan.
Feline immunodeficiency virus can infect a human cell line (MOLT-4) but establishes a state of latency in the cells.: J Gen Virol. 1996 Aug;77 ( Pt 8):1623-30. Unique Identifier : AIDSLINE MED/96332498; Ikeda Y; Tomonaga K; Kawaguchi Y; Kohmoto M; Inoshima Y; Tohya Y; Miyazawa T; Kai C; Mikami T; Department of Microbiology, Faculty of Agriculture, University of; Tokyo, Japan.; Infectivity of feline immunodeficiency virus (FIV) in feline and human lymphoblastoid cell lines was examined using homogeneous populations of FIV derived from infectious molecular clones of strains TMZ and Petaluma, and two recombinant chimeric clones carrying gag, pol, vif and ORF-A from the heterologous virus. FIV e
The structure and phylogeny of a new family of human endogenous retroviruses.: J Gen Virol. 1996 Aug;77 ( Pt 8):1631-41. Unique Identifier : AIDSLINE GENBANK/U37066; Widegren B; Kjellman C; Aminoff S; Sahlford LG; Sjogren HO; Department of Tumor Immunology, Wallenberg Laboratory,; Solvegatan, Lund, Sweden. Bengt.Widegren@wblab.lu.se; A novel endogenous retrovirus (ERV) designated XA34 was isolated from a human glioma cDNA library using low stringency hybridization with an ERV-9 env probe. Southern blot hybridizations with human genomic DNA revealed the presence of approximately 16 genomic copies closely related to XA34. Sequencing of a 2303 bp cDNe
The human immunodeficiency virus type 1 regulatory protein Tat inhibits interferon-induced iNos activity in a murine macrophage cell line.: J Gen Virol. 1996 Aug;77 ( Pt 8):1643-7. Unique Identifier : AIDSLINE MED/96332500; Barton CH; Biggs TE; Mee TR; Mann DA; Department of Biochemistry, University of Southampton, UK.; CHB@Soton.ac.uk; Human immunodeficiency virus type 1 (HIV-1) infection is frequently associated with concurrent infection by opportunistic pathogens, against which production of nitric oxide by host macrophages provides a first line of defence. We have investigated whether regulatory HIV-1 proteins, such as Tat, can modulate the active
Genomic and biological alteration of a human immunodeficiency virus type 1 (HIV-1)-simian immunodeficiency virus strain mac chimera, with HIV-1 Env, recovered from a long-term carrier monkey.: J Gen Virol. 1996 Aug;77 ( Pt 8):1649-58. Unique Identifier : AIDSLINE MED/96332501; Igarashi T; Kuwata T; Takehisa J; Ibuki K; Shibata R; Mukai R; Komatsu T; Adachi A; Ido E; Hayami M; Institute for Virus Research, Kyoto University, Japan.; A macaque monkey infected with NM-3, a human immunodeficiency virus type 1 (HIV-1)-simian immunodeficiency virus strain mac (SIVmac) chimeric virus with env, rev, tat and vpu derived from HIV-1 and LTR, gag, pol, vif and vpx derived from SIVmac, became a long-term carrier (more than 2.8 years). This monkey produced nee
Fine-specificity of cytotoxic T lymphocytes which recognize conserved epitopes of the Gag protein of human immunodeficiency virus type 1.: J Gen Virol. 1996 Aug;77 ( Pt 8):1659-65. Unique Identifier : AIDSLINE MED/96332502; van Baalen CA; Klein MR; Huisman RC; Dings ME; Kerkhof Garde SR; Geretti AM; Gruters R; van Els CA; Miedema F; Osterhaus AD; Institute of Virology, Erasmus University, Rotterdam, The; Netherlands.; Human immunodeficiency virus type 1 (HIV-1) Gag-specific cytotoxic T lymphocyte (CTL) responses were studied in seven seropositive long-term asymptomatic individuals (CDC A1) with stable CD4 counts for more than 8 years. Using a set of partially overlapping peptides covering the whole Gag, five 15-20-mer peptides weree
Human antibodies that neutralize primary human immunodeficiency virus type 1 in vitro do not provide protection in an in vivo model.: J Gen Virol. 1996 Aug;77 ( Pt 8):1667-75. Unique Identifier : AIDSLINE MED/96332503; Schutten M; Tenner-Racz K; Racz P; van Bekkum DW; Osterhaus AD; Erasmus University Rotterdam, Department of Virology, The; Netherlands.; Recently, conflicting data have been published about the ability of antibodies which efficiently neutralize T cell-adapted human immunodeficiency virus type 1 (HIV-1) strains to neutralize primary HIV-1 strains in vitro and in vivo. Here we present data indicating that such antibodies fail to neutralize primary HIV-1 e
HIV inhibitory natural products. 26. Quinoline alkaloids from Euodia roxburghiana.: J Nat Prod. 1996 May;59(5):469-71. Unique Identifier : AIDSLINE MED/96231641; McCormick JL; McKee TC; Cardellina JH 2nd; Boyd MR; Laboratory of Drug Discovery Research and Development,; Developmental Therapeutics Program, National Cancer Institute,; Frederick, Maryland 21702-1201, USA.; Bioassay-directed fractionation of the CH2Cl2-MeOH extract of Euodia roxburghiana resulted in the isolation of two known quinoline alkaloids, buchapine (1) and 2, and three new furoquinoline alkaloids, roxiamines A, B, and C (3-5). Compounds 1 and 2 protected CEM-SS cells from the cytopathic effects of HIV-1 in vitro e
Nigranoic acid, a triterpenoid from Schisandra sphaerandra that inhibits HIV-1 reverse transcriptase.: J Nat Prod. 1996 May;59(5):525-7. Unique Identifier : AIDSLINE MED/96231645; Sun HD; Qiu SX; Lin LZ; Wang ZY; Lin ZW; Pengsuparp T; Pezzuto JM; Fong HH; Cordell GA; Farnsworth NR; Laboratory of Phytochemistry, Kunming Institute of Botany,; Chinese Academy of Sciences, Yunnan, People's Republic of China.; An A ring-secocycloartene triterpenoid, nigranoic acid (3,4-secocycloarta-4(28),24-(Z)-diene-3,-26-dioic acid, (1) was isolated from the stems of Schisandra sphaerandra, a Chinese traditional medicinal plant. Its structure elucidation and unambiguous NMR spectral assignment were achieved by the combination of 1D- and e
Patients, needles, and healthcare workers: understanding the epidemiology, pathophysiology, and transmission of the human immunodeficiency virus, hepatitis B and C, and cytomegalovirus.: J Intraven Nurs. 1995 Nov-Dec;18(6 Suppl):S22-31. Unique Identifier : AIDSLINE MED/96345371; Hibberd PL; The risk of transmission of bloodborne pathogens in the healthcare environment is determined by three main factors: the nature and frequency of exposure to blood or body fluids; the risk of transmission of infection after a single exposure to the pathogen; and the prevalence of infected and susceptible patients and hee
Integrating the Occupational Safety & Health Administration mandates on bloodborne pathogens in the practice setting.: J Intraven Nurs. 1995 Nov-Dec;18(6 Suppl):S9-16. Unique Identifier : AIDSLINE MED/96345369; Williams HF; The Occupational Safety & Health Administration Bloodborne Pathogen Standard was developed to reduce the risk of exposure of healthcare workers to hepatitis B and C, human immunodeficiency virus, and other bloodborne pathogens. This can only be achieved if all healthcare workers continue to work to understand, adhe
[Synthetic inhibitors targeting serine and aspartic acid proteases]: J Pharm Belg. 1996 May-Jun;51(3):161-4. Unique Identifier : AIDSLINE MED/96258627; Reboud-Ravaux MC; Boggetto ND; Doucet CE; de Rosny EH; Vergely IB; Thierry NM; Amour AJ; Departement de Biologie Supramoleculaire et Cellulaire,; Institut Jacques Monod, Universite de Paris VII, France.; reboud@ccr.jussieu.fr; The interaction of novel series of synthetic inhibitors with various serine proteases (leukocyte elastase, thrombin, cathepsin G, chymotrypsin, plasminogen activators and plasmin) and an aspartic protease (HIV-1 protease) were studied. Various aspects were analyzed: mechanism of action, structure-activity relationship
HIV infection masquerading as Sjogren's disease: a clinical dilemma.: J Miss State Med Assoc. 1996 Jul;37(7):645-6. Unique Identifier : AIDSLINE MED/96334173; Nunenmacher SJ; Holbert RD; Davidson EM; Biloxi Regional Medical Center, MS, USA.
A characteristic bent conformation of RNA pseudoknots promotes -1 frameshifting during translation of retroviral RNA.: J Mol Biol. 1996 Jul 26;260(4):479-83. Unique Identifier : AIDSLINE MED/96319745; Chen X; Kang H; Shen LX; Chamorro M; Varmus HE; Tinoco I Jr; Department of Chemistry, University of California, Berkeley; 94720, USA.; The structures of four different RNA pseudoknots that provide one of the signals required for ribosomal frameshifting in mouse mammary tumor virus have been determined by NMR. The RNA pseudoknots have similar sequences and assume similar secondary structures, but show significantly different frameshifting efficiencies
DNA-stacking interactions determine the sequence specificity of the deoxyribonuclease activity of 1,10-phenanthroline-copper ion.: J Mol Biol. 1996 Jul 26;260(4):523-39. Unique Identifier : AIDSLINE MED/96319749; Schaeffer F; Rimsky S; Spassky A; Unite de Physicochimie des Macromolecules Biologiques, CNRS; URA1149, Institut Pasteur, Paris, France.; Bis(1,10-phenanthroline)-copper(I) ion (OP2Cu+) binds reversibly to B-DNA and makes single-stranded cuts by oxidative attack on the deoxyribose moiety. The deoxyribonuclease activity is sequence-dependent yet not nucleotide-specific at the cutting site. OP2Cu+ sequence specificity was analysed in terms of local variat
Peptide libraries define the fine specificity of anti-polysaccharide antibodies to Cryptococcus neoformans.: J Mol Biol. 1996 Aug 9;261(1):11-22. Unique Identifier : AIDSLINE MED/96335201; Valadon P; Nussbaum G; Boyd LF; Margulies DH; Scharff MD; Department of Cell Biology, Albert Einstein College of Medicine,; Bronx, NY 10461, USA.; Cryptococcus neoformans is an encapsulated fungus that causes a life-threatening meningoencephalitis in patients with AIDS. Monoclonal antibodies to the capsular glucuronoxylomannan can modulate the infection in mice, but the epitopes on this complex polysaccharide recognized by protective and non-protective antibodie
Scientists figure out what makes HIV stick [news]: J Natl Cancer Inst. 1996 Aug 21;88(16):1102-3. Unique Identifier : AIDSLINE MED/96347984; Kuska B
Rupture of the pathologic spleen: is there a role for nonoperative therapy?: J Trauma. 1996 Aug;41(2):214-8. Unique Identifier : AIDSLINE MED/96332351; Guth AA; Pachter HL; Jacobowitz GR; Bellevue Hospital Center, New York University Medical Center, New; York, New York 10016, USA.; INTRODUCTION: While nonoperative management of blunt splenic injury in the stable patient has become the standard of care, splenectomy is still advocated as the safest management for rupture of the diseased spleen. The combination of splenectomy and underlying immunosuppression may render these patients particularly s
Human immunodeficiency virus and the trauma patient: factors influencing postoperative infectious complications.: J Trauma. 1996 Aug;41(2):251-5; discussion 255-6. Unique Identifier : AIDSLINE MED/96332357; Guth AA; Hofstetter SR; Pachter HL; Shock and Trauma Unit, Bellevue Hospital Center, New York; University Medical Center, NY 10016, USA.; OBJECTIVE: While immunosuppression 2 degrees to human immunodeficiency virus (HIV) infection should logically render HIV+ trauma victims more prone to infection after injury, little data is available regarding trauma outcome in this group of patients. Since the helper CD4+ lymphocyte count is a marker for progression
[An AIDS case of probable pentamidine-induced diabetic ketoacidosis and severe acute pancreatitis]: Nippon Shokakibyo Gakkai Zasshi. 1996 Mar;93(3):226-30. Unique Identifier : AIDSLINE MED/96317908; Pae Y; Koyanagi S; Sawayama Y; Tani Y; Hayashi J; Kashiwagi S; Department of General Medicine, Kyusyu University, Japan.
[Analysis of cells and proteins in bronchoalveolar lavage fluid]: Nippon Kyobu Shikkan Gakkai Zasshi. 1996 Mar;34(3):259-65. Unique Identifier : AIDSLINE MED/96236995; Hanaoka M; Fujimoto K; Hayasaka M; Kubo K; Kobayashi T; Sekiguchi M; Honda T; First Department of Internal Medicine, Shinshu University, School; of Medicine, Matsumoto, Japan.; We studied cells and proteins in bronchoalveolar lavage fluid examined at the First Department of Internal Medicine of Shinshu University Hospital between 1990 and 1994. The samples came from 21 healthy subjects and from 216 patients with various diseases. Lymphocyte counts were abnormally high in patients with bronch
An attributional analysis of suicide.: J Soc Psychol. 1996 Jun;136(3):399-400. Unique Identifier : AIDSLINE MED/96305778; Lester D; Center for the Study of Suicide, Blackwood, NJ 08012, USA.
Clinical investigation of traditional Chinese medicine and pharmacy in treating respiratory tract infections in AIDS.: J Tradit Chin Med. 1996 Mar;16(1):3-6. Unique Identifier : AIDSLINE MED/96335935; Li G; Yue Y; Lu W; Zhou Z; Guang An Men Hospital, China Academy of Traditional Chinese; Medicine, Beijing.; Based on the difference in severity of the disease and complications, 80 cases of acquired immune-deficiency syndrome (AIDS) accompanied with cough were divided into 2 groups: One treated by traditional Chinese medicine (TCM group), including 58 cases and the other treated by Integrated Chinese and Western medicine (i
[A case of tropical spastic paraparesis associated with HTLV1 in the Niger Republic (letter)]: Med Trop (Mars). 1996;56(1):100-1. Unique Identifier : AIDSLINE MED/96289774; Develoux M; Dupont A; Meynard D; Delaporte E
[What's going on with leprosy in 1996? Update of the French Speaking Leprosy Specialists congress (Yaounde, January 1996)]: Med Trop (Mars). 1996;56(1):13-6. Unique Identifier : AIDSLINE MED/96289752; Saint-Andre P; l'Ecole de Medecine du Mali, Marseille, France.
[New opportunistic pathogens in AIDS]: Med Trop (Mars). 1996;56(1):17-20. Unique Identifier : AIDSLINE MED/96289753; Morillon M; Laboratoire de Biologie Clinique, Marseille-Armees, France.
[AIDS-related cryptococcal meningitis at the Bobo-Dioulasso Hospital Center: five case reports]: Med Trop (Mars). 1996;56(1):63-5. Unique Identifier : AIDSLINE MED/96289765; Ki-Zerbo GA; Sawadogo A; Millogo A; Andonaba JB; Yameogo A; Ouedraogo I; Tamini M; Konate B; Durand G; Service de Medecine Interne, I'Hopital National Souro Sanou,; Bobo-Dioulasso, Burkina Faso.; The authors report five cases of Cryptococcus neoformans meningitis in HIV-positive patients hospitalized in the Souro Sanou National Hospital Center of Bobo-Dioulasso ( Burkina Faso ). There were 3 men and 2 women with a mean age of 36 years (range: 29 to 47 years). Presenting symp
[Mycosis fungoides in a Gabonese patient infected with HTLV-I]: Med Trop (Mars). 1996;56(1):66-8. Unique Identifier : AIDSLINE MED/96289766; Perret JL; Moussavou-Kombila JB; Delaporte E; Coniquet S; Nguemby-Mbina C; Normand P; Service de Medecine A, Centre Hospitalier de Libreville, Gabon.; Association of human T-lymphotropic virus type-1 (HTLV-1) with T-cell malignancy is well-known but its relationship with mycosis fungoides is controversial. Typical mycosis fungoides was diagnosed at tumor stage in a 58-year-old Gabonese woman also infected with HTLV-1. Infection with lymphoma of the skin is uncommon
[Trypanosoma cruzi in French Guinea: review of accumulated data since 1940]: Med Trop (Mars). 1996;56(1):79-87. Unique Identifier : AIDSLINE MED/96289769; Raccurt CP; Service de Parasitologie et de Mycologie Medicales, Faculte de; Medecine des Antilles, Cayenne, Guyane Francaise.; Between 1939 and 1994, nine cases of Chagas disease have been reported in French Guiana : seven in the acute phase including two that were fatal and two in the chronic phase with cardiac sequellae. A tenth case of transient parasitem
Sequence analysis of human T cell lymphotropic virus type I (HTLV-I) Env genes amplified from central nervous system tissues of patients with HTLV-I-associated myelopathy or leukemia.: Microb Pathog. 1995 Nov;19(5):317-33. Unique Identifier : AIDSLINE MED/96255672; Maroushek SR; Osame M; Izumo S; Kubota R; Sato E; Bartholomew C; Haase AT; Department of Microbiology, University of Minnesota, Minneapolis; 55455, USA.; Human T cell lymphotropic virus type I (HTLV-I) is a retrovirus that has been linked to HTLV-I-associated myelopathy (HAM)/tropical spastic paraparesis (TSP), a chronic or inflammatory neurological disease with some resemblance to multiple sclerosis. We used the polymerase chain reaction to amplify viral env genes in
Conclusions of a round-table that took place during a seminar on the prevention of TB and HIV transmission in health care settings, Douala, Cameroon, January 1995.: Midwifery. 1996 Mar;12(1):39-40. Unique Identifier : AIDSLINE MED/96361034
[Salivary HIV antibodies. Review of current data and future prospectives]: Minerva Stomatol. 1995 Dec;44(12):583-90. Unique Identifier : AIDSLINE MED/96308476; Polimeni A; Gallottini L; Resi JP; Facolta di Medicina e Chirurgia, Universita degli Studi di; Roma, La Sapienza.; Medical researchers, especially those involved in AIDS studies, have shown increasing interest in the salivary diagnosis in the recent years. Saliva sample collection is simple, quick, non traumatic and it can be done at low cost. Moreover saliva specimens can be collected without significant infection risks for both
[Oral lesions in Kaposi sarcoma: clinical and radiotherapeutic considerations]: Minerva Stomatol. 1996 Jan-Feb;45(1-2):17-27. Unique Identifier : AIDSLINE MED/96308799; Barberis M; Brenna Betti N; Lauritano D; Sangiani L; Spadari F; Villa S; Istituto Scientifico Ospedale San Raffaele, Universita degli; Studi, Milano.; The epidemic form of Kaposi s sarcoma is the most frequent tumor in sieropositive patients. Every part of the body including oral cavity is affected by these lesions. According to modern acknowledgement in treating oropharynge carcinoma, radiotherapy is used for management of oral Kaposi s sarcoma. This paper reports
HIV testing among women aged 18-44 years--United States, 1991 and 1993.: MMWR Morb Mortal Wkly Rep. 1996 Aug 30;45(34):733-7. Unique Identifier : AIDSLINE MED/96368023; Human immunodeficiency virus (HIV) infection is a major cause of morbidity and mortality among women and children in the United States . In 1995, of the 73,380 acquired immunodeficiency syndrome (AIDS) cases reported, women accounted for 13,764 (19%). HIV infection is the third leading
The effects of immunization in human immunodeficiency virus type 1 infection [letter]: N Engl J Med. 1996 Sep 12;335(11):817; discussion 818-9. Unique Identifier : AIDSLINE MED/96361319; Farber CM; Barath AA; Dieye T
The effects of immunization in human immunodeficiency virus type 1 infection [letter]: N Engl J Med. 1996 Sep 12;335(11):817-8; discussion 818-9. Unique Identifier : AIDSLINE MED/96361320; Kroon FP; Van Furth R; Bruisten SM
Testing for antibodies in Kaposi's sarcoma [letter]: N Engl J Med. 1996 Sep 12;335(11):819; discussion 819-20. Unique Identifier : AIDSLINE MED/96361321; Martin JN; Gerberding JL; Osmond DH
Forum to advance trials for AIDS therapies [news]: Nature. 1996 Aug 15;382(6592):566. Unique Identifier : AIDSLINE MED/96338205; Macilwain C
Nutrition and immunity with emphasis on infection and autoimmune disease.: Nutr Health. 1996;10(4):285-312. Unique Identifier : AIDSLINE MED/96354057; Harbige LS; Division of Immunology, United Medical School of Guy's and St.; Thomas's Hospital, Rayne Institute, London, UK.; 1.harbige@umds.ac.uk; Nutrition and nutritional status can have profound effects on immune functions, resistance to infection and autoimmunity in man and other animals. Nutrients enhance or depress immune function depending on the nutrient and level of its intake. Protein-energy malnutrition and vitamin A deficiency are strongly associated
Court rules in DSSNY's favor in state human rights dispute.: N Y State Dent J. 1996 Jun-Jul;62(6):28-9. Unique Identifier : AIDSLINE MED/96321714; Plunkett L
Right to die issue raises complicated ethical questions [editorial]: ONS News. 1996 Apr;11(4):3. Unique Identifier : AIDSLINE MED/96358996; Nevidjon B
Invasive aspergillosis of the larynx in AIDS.: Otolaryngol Head Neck Surg. 1996 Jul;115(1):135-7. Unique Identifier : AIDSLINE MED/96338145; Kingdom TT; Lee KC; Department of Otolaryngology-Head and Neck Surgery, University of; California, San Francisco, 94143, USA.
Children with HIV becoming adolescents: caring for long-term survivors.: Pediatr Nurs. 1996 May-Jun;22(3):220-3, 227, 255. Unique Identifier : AIDSLINE MED/96359034; Riddel J; Moon MW; As children infected with HIV live longer, pediatric nurses who care for these patients need to be familiar with adolescent development and to anticipate physiologic and behavioral changes that will occur in this population. Concerns regarding confidentiality, autonomy, medication needs and compliance may become param
Scores on sensation seeking as a predictor of sexual activities among homosexuals.: Percept Mot Skills. 1996 Apr;82(2):657-8. Unique Identifier : AIDSLINE MED/96283226; Schroth ML; Department of Psychology, Santa Clara University, CA 95053, USA.; Sensation seeking scores were positively correlated with the variety of homosexual activities and the number of homosexual partners within a gay population of 100. However, sensation seeking scores were not correlated with risky sexual practices.
Unexpected anisotropy in substrate cleavage rates by asymmetric hammerhead ribozymes.: Nucleic Acids Res. 1996 Jul 15;24(14):2679-84. Unique Identifier : AIDSLINE MED/96313230; Hendry P; McCall M; CSIRO, Division of Biomolecular Engineering, North Ryde, NSW,; Australia.; RNA substrates which form relatively short helices I and III with hammerhead ribozymes are generally cleaved more rapidly than substrates which create longer binding helices. We speculated that for optimum cleavage rates, one of the helices needed to be relatively weak. To identify this helix, a series of ribozymes an
In vitro expansion of GGC:GCC repeats: identification of the preferred strand of expansion.: Nucleic Acids Res. 1996 Jul 15;24(14):2835-40. Unique Identifier : AIDSLINE MED/96313254; Ji J; Clegg NJ; Peterson KR; Jackson AL; Laird CD; Loeb LA; Joseph Gottstein Memorial Cancer Research Laboratory, Department; of Pathology and Biochemistry, University of Washington, Seattle; 98195, USA.; The human fragile-X syndrome, a major cause of inherited mental retardation, is associated with expansion of the trinucleotide repeat GGC:GCC. Repetitive sequences in DNA are subject to slippage during catalysis by DNA polymerases. We characterized the extent of slippage of synthetic GGC:GCC repeats by various DNA pol
Tuberculosis: what nurses need to know to help control the epidemic [letter]: Nurs Outlook. 1996 Mar-Apr;44(2):103-4. Unique Identifier : AIDSLINE MED/96298078; Lancaster E
No sanctuary from HIV funding cuts [news]: Nurs Times. 1996 May 15-21;92(20):19. Unique Identifier : AIDSLINE MED/96356932; Cervi B
Women's sexual health care: bringing down the barriers.: Nurs Times. 1996 May 15-21;92(20):39-41. Unique Identifier : AIDSLINE MED/96356939; Hayward M; This paper follows the course of a health promotion project aimed at encouraging sexually active women to carry and use barrier contraceptives to maintain positive sexual health. It was carried out by four nursing students on a night diploma course at the University of Portsmouth. Having established a need and target
Albendazole may reduce diarrhoea in HIV patients.: Nurs Times. 1996 May 22-28;92(21):12-3. Unique Identifier : AIDSLINE MED/96356947; Kelly P; Lungu F; Keane E
Should people with HIV infection receive transplants?: Nurs Times. 1996 May 29-Jun 4;92(22):39-40. Unique Identifier : AIDSLINE MED/96358954; Purton C; This paper examines whether potential organ recipients should be screened for HIV/AIDS. Written by a former staff nurse at a liver unit, it outlines the results of a survey of transplant centres. The author argues for pre- and post-test counselling and calls for a protocol to be set up as a guide to testing.
HIV survival rates [news]: Nurs Times. 1996 Jun 12-8;92(24):6. Unique Identifier : AIDSLINE MED/96358960
[Tuberculosis in a Parisian internal medicine hospital unit. 50 cases (letter)]: Presse Med. 1995 Dec 16-23;24(39):1911. Unique Identifier : AIDSLINE MED/96307510; Haas C; Laroche-Le Dinh C; Lowenstein W; Durand H
[Risk factors of the occurrence of cerebral toxoplasmosis in patients with HIV infection. Definition of indications of primary prevention. Proposals of the Toxoplasmosis and other protozoan infections Group. Coordinated action N.5 - 1996 February (news)]: Presse Med. 1996 Mar 30;25(11):519-20. Unique Identifier : AIDSLINE MED/96306460; Leport C; Ambroise-Thomas P; Bazin C; Chene G; Derouin F; Katlama C; Mayaud C; Pelloux H; Raffi F; Vilde JL
[Retrospective evaluation of the detection of Toxoplasma gondii by polymerase chain reaction in AIDS patients]: Presse Med. 1996 Mar 30;25(11):541-5. Unique Identifier : AIDSLINE MED/96306464; Robert F; Ouatas T; Blanche P; Tourte-Schaefer C; Sicard D; Dupouy-Camet J; Laboratoire de Parasitologie, Hopital Cochin, Paris.; OBJECTIVES: We retrospectively evaluated routine detection of Toxoplasma gondii by polymerase chain reaction (PCR) amplification of the B1 gene and the TGR 1E sequence in blood and CSF samples from patients with acquired immune deficiency syndrome (AIDS) and suspected toxoplasmosis. METHODS: From January 1993 to Febru
[Salmonella typhimurium cerebral abscess: rare complication of HIV infection (letter)]: Presse Med. 1996 Mar 30;25(11):556. Unique Identifier : AIDSLINE MED/96306469; Smail A; Lafon B; Toussaint P; Masmoudi K; Leclerc N; Ducroix JP; Baillet J
Breast abscess with lethal septicemia due to Pseudomonas aeruginosa in a patient with AIDS.: Presse Med. 1996 May 18;25(17):803-4. Unique Identifier : AIDSLINE MED/96332387; Roca B; Vilar C; Perez EV; Saez-Royuela A; Simon E; Infectious Diseases Unit, Hospital General, Castellon, Spain.; OBJECTIVE: The incidence of Pseudomonas aeruginosa in HIV-infected patients has increased over the last years. We describe a case of pseudomonal breast abscess complicated with fatal septicemia in an AIDS patient. CASE REPORT: A 21-year-old woman was admitted for fever, chills, nausea, vomiting and pain in the breast.
[Human immunodeficiency virus infection in pregnancy. General aspects]: Presse Med. 1996 Jan 20;25(2):77-80. Unique Identifier : AIDSLINE MED/96307485; d'Ercole C; Cravello L; Sperandeo D; Bretelle F; Piechon L; Boubli L; Blanc B; Service de Gynecologie-Obstetrique B, Hopital de la; Conception, Marseille.; Seroprevalence of HIV infection in pregnancy is on the increase worldwide. Approximately 10 million infants will have been infected by the year 2000 and the majority of these children will have acquired infection by vertical transmission of HIV from infected mothers. Recent reports suggested that pregnancy does not ac
[Asymptomatic pulmonary pneumocytosis accidentally discovered in a patient with HIV infection (letter)]: Presse Med. 1996 Jan 20;25(2):81. Unique Identifier : AIDSLINE MED/96307486; Schott R; Fraisse P; Neidhardt AC; Jaquemin C; Partisani M; Rey D; Lang JM; Weitzenblum E
[Acid-alcohol-resistant bacilli detected by microscopic analysis of exhaled air from HIV-infected patients: tuberculosis or mycobacteriosis?]: Presse Med. 1996 Feb 10;25(5):193-6. Unique Identifier : AIDSLINE MED/96307257; Meynard JL; Lalande V; Selle F; Guiguet M; Meyohas MC; Picard O; Duvivier C; Petit JC; Frottier J; Service des Maladies infectieuses et tropicales, Hopital; Saint-Antoine, Paris.; OBJECTIVES: The incidence of atypical mycobacterial infections has increased with the AIDS epidemic. To present, microscopic examinations of airway specimens positive for acid-fast bacteria were highly suggestive of tuberculosis. However, since the AIDS epidemic, certain authors have reported an increase in Mycobacter
[Visceral localizations of cat-scratch disease in an immunocompetent patient]: Presse Med. 1996 Feb 10;25(5):199-201. Unique Identifier : AIDSLINE MED/96307259; Bouchard O; Bosseray A; Leclercq P; Micoud M; Hopital Michallon, CHU de Grenoble.; Locoregional expression of cat scratch disease is well known, but despite advances in microbiology over the last 10 years leading to the description of two new bacteria (Afipia felis, Bartonella henselae) the infective agent responsible for cat scratch syndrome remains unknown. Until the 80s, only one systemic disease
Catabolic hormones and growth hormone resistance in acquired immunodeficiency syndrome and other catabolic states.: Proc Soc Exp Biol Med. 1996 Sep;212(4):324-31. Unique Identifier : AIDSLINE MED/96355826; Rodgers BD; Group in Endocrinology, University of California, Berkeley 94720,; USA.
[Test for virus genotype (PCR) for greater safety in blood preparations]: Pharm Unserer Zeit. 1996 Apr;25(2):105. Unique Identifier : AIDSLINE MED/96242874
[Even HIV subtype E is not transmitted by kissing]: Pharm Unserer Zeit. 1996 Apr;25(2):106. Unique Identifier : AIDSLINE MED/96242875
Odor sensitivity is impaired in HIV-positive cognitively impaired patients.: Physiol Behav. 1996 Apr-May;59(4-5):877-81. Unique Identifier : AIDSLINE MED/96270865; Razani J; Murphy C; Davidson TM; Grant I; McCutchan A; SDSU-UCSD Joint Doctoral Program in Clinical Psychology, San; Diego, CA 92120, USA.; An estimated 7-28% of patients infected by the human immunodeficiency virus (HIV) develop dementia and at least 50% develop mild neurocognitive impairment. Past studies have shown odor identification impairments in HIV + neurocognitively impaired patients. It is difficult, however,
OB clinic rejects patient refusing HIV test: nurse sued. Case in point: Atapka v. Perimeter OB-GYN Associates, Inc. 912 F. Supp. 1566--GA (1996).: Regan Rep Nurs Law. 1996 May;36(12):2. Unique Identifier : AIDSLINE MED/96359097; Tammelleo AD
Drug delivery during pregnancy: evaluation in vitro of new drugs.: Reprod Fertil Dev. 1995;7(6):1485-9. Unique Identifier : AIDSLINE MED/96293598; Dancis J; Liebes L; Department of Pediatrics, New York University School of Medicine,; New York 10016, USA.; Indications for the treatment of the pregnant woman fall into three general categories: mother and infant require treatment, only the mother should be treated, or only the infant. Directing therapy towards the affected subject is an important aspect of good care, although it is not the only one. It is argued that a ra
[Recent advances in studies of IL-12]: Sheng Li Ko Hsueh Chin Chan. 1995 Oct;26(4):355-8. Unique Identifier : AIDSLINE MED/96331371; Chen AH
Human immunodeficiency virus-associated atypical mycobacterial skeletal infections.: Semin Arthritis Rheum. 1996 Apr;25(5):347-56. Unique Identifier : AIDSLINE MED/96272078; Hirsch R; Miller SM; Kazi S; Cate TR; Reveille JD; Department of Medicine, University of Texas Health Science; Center-Houston 77225, USA.; The clinical and laboratory features of six human immunodeficiency virus (HIV)-positive patients with atypical mycobacterial skeletal infections, seen at a county outpatient HIV facility or university outpatient clinic, are reviewed and compared with other reported cases. Atypical mycobacterial skeletal infections are
[Angioimmunoblastic lymphadenopathy: comparison of 2 clinical cases, one of them with antibodies against human immunodeficiency virus (HIV) (letter)]: Sangre (Barc). 1996 Feb;41(1):72. Unique Identifier : AIDSLINE MED/96214376; Hernandez DE; Da Costa O; Rodriguez A
Determinants of the growth in the Social Security Administration's disability programs--an overview.: Soc Secur Bull. 1995 Winter;58(4):43-70. Unique Identifier : AIDSLINE MED/96267530; Rupp K; Stapleton D; This article examines factors affecting the growth in the Social Security Administration s disability programs. We synthesize recent empirical evidence on factors affecting trends in applications and awards for Disability Insurance and Supplemental Security Income (SSI) benefits and duration on the rolls. Econometric
Endemic mycosis complicating human immunodeficiency virus infection.: West J Med. 1996 Apr;164(4):335-40. Unique Identifier : AIDSLINE MED/96308808; Sarosi GA; DAvies SF; Santa Clara Valley Medical Center, San Jose, California, USA.; Persons infected with the human immunodeficiency virus are prone to the development of many fungal diseases. Normal hosts with intact immunity usually recover from infection by these less-invasive fungi. In persons with compromised T-cell-mediated immunity, however, widespread dissemination from a pulmonary focus occu
The effect of supplemental beta-carotene on immunologic indices in patients with AIDS: a pilot study.: Yale J Biol Med. 1995 Jan-Apr;68(1-2):19-23. Unique Identifier : AIDSLINE MED/96353428; Fryburg DA; Mark RJ; Griffith BP; Askenase PW; Patterson TF; Division of Endocrinology and Metabolism, Yale University School; of Medicine, New Haven, Connecticut, USA.; Patients with the acquired immunodeficiency syndrome (AIDS) are characterized by a decrease in the number of T helper cells, a defect that is linked to the impaired immunologic competence. Vitamin A and its dietary precursor, beta-carotene, increase absolute T helper cell counts as well as indices of T cell function i
Cell-mediated immunity of patients who have had basal cell carcinomas.: Acta Derm Venereol. 1996 Jan;76(1):28-30. Unique Identifier : AIDSLINE MED/96281987; Czarnecki D; Mar A; Kulinskaya E; Department of Dermatology, Heidelberg Hospital, Melbourne,; Australia.; The cell-mediated immunity of patients who had basal cell carcinomas (BCCs) removed was studied by measuring cuntaneous delayed hypersensitivity reactions to recall antigens (Multitest CMI, Pasteur-Merieux), and by measuring lymphocyte counts and subsets. One group of patients had multiple BCCs (3 or more) removed and
Morphologic features and clinical significance of skin involvement in patients with AIDS-related cryptococcosis.: Acta Derm Venereol. 1996 Jan;76(1):72-4. Unique Identifier : AIDSLINE MED/96282001; Manfredi R; Mazzoni A; Nanetti A; Mastroianni A; Coronado O; Chiodo F; Institute of Infectious Diseases, University of Bologna, Italy.; Eight out of 30 consecutive patients with AIDS and cryptococcal meningoencephalitis (26,7%) presented cutaneous involvement, in the form of papulo-nodular lesions in 3 patients, molluscum contagiosum-like lesions in 3 patients, and pustular-ulcerative lesions in 2 patients. Skin localization represented an untoward pr
Intralesional bleomycin for the treatment of non-genital warts in HIV-infected patients [letter]: Acta Derm Venereol. 1996 Jan;76(1):81-2. Unique Identifier : AIDSLINE MED/96282007; Shah M; Murphy M; Price JD; Lacey CJ
Oxytocin mRNA in the human paraventricular nucleus in AIDS.: Adv Exp Med Biol. 1995;395:91. Unique Identifier : AIDSLINE MED/96283868; Guldenaar SE; Swaab DF; Graduate School of Neurosciences Amsterdam, Netherlands Institute; for Brain Research, The Netherlands.
Current uses and abuses of total parenteral nutrition.: Adv Surg. 1996;29:165-89. Unique Identifier : AIDSLINE MED/96359653; Archer SB; Burnett RJ; Fischer JE; Department of Surgery, University of Cincinnati Medical Center,; Ohio, USA.; Total parenteral nutrition remains a vital medical intervention, and in our institution it is considered as basic as intravenous fluids, antibiotics, and blood transfusions. As is true of most treatments, there are specific indications as well as associated risks and costs which mandate justification of its use. It is
Public or private?... that is the question.: Am J Orthod Dentofacial Orthop. 1996 Aug;110(2):231-2. Unique Identifier : AIDSLINE MED/96339282; Jerrold L
Captopril and renal survival in patients with human immunodeficiency virus nephropathy.: Am J Kidney Dis. 1996 Aug;28(2):202-8. Unique Identifier : AIDSLINE MED/96320146; Kimmel PL; Mishkin GJ; Umana WO; Department of Medicine, George Washington University Medical; Center, Washington, DC 20037, USA.; The pathogenesis of human immunodeficiency virus-associated nephropathy (HIVAN) is unknown, but it is characterized by aggressive glomerulosclerosis, tubulopathy, and interstitial inflammation. Currently, no therapy has been proven effective for HIVAN. Angiotensin II has been implicated in the pathogenesis of progress
Systemic lupus erythematosus in two adults with human immunodeficiency virus infection.: Am J Kidney Dis. 1996 Aug;28(2):292-5. Unique Identifier : AIDSLINE MED/96320161; Contreras G; Green DF; Pardo V; Schultz DR; Bourgoignie JJ; Department of Medicine, University of Miami School of Medicine,; FL, USA.
Facilitator report: bloodborne pathogens exposure among health care workers.: Am J Ind Med. 1996 Apr;29(4):418-20. Unique Identifier : AIDSLINE MED/96284654; Gershon R; School of Hygiene and Public Health, Johns Hopkins University,; Baltimore, MD 21205, USA.; Several psychosocial and organizational factors have been identified as important correlates of compliance with safe work practices among health care workers. In particular, compliance with universal precautions--a set of work practices which were designed to minimize exposure to bloodborne pathogens--has been found t
Should infection control practitioners do follow-up of staff exposures to patient blood and body fluids?: Am J Infect Control. 1996 Apr;24(2):57-66. Unique Identifier : AIDSLINE MED/96293275; Hope KM; Henderson E; Ledgerwood D; Hume K; Louie TJ; Calgary General Hospital, Alberta, Canada.; BACKGROUND: The purpose of this study was to determine the efficiency of a joint infection control/occupational health program for the follow-up of accidental blood or bloody body fluid exposures in health care workers. METHODS: A comprehensive staff follow-up program for all blood exposures with known patient sources
Factors associated with unrecognized HIV-1 infection in an inner-city emergency department.: Ann Emerg Med. 1996 Aug;28(2):159-64. Unique Identifier : AIDSLINE MED/96322272; Alpert PL; Shuter J; DeShaw MG; Webber MP; Klein RS; Department of Medicine, Montefiore Medical Center, Bronx, NY,; USA.; STUDY OBJECTIVE: To determine the prevalence of and risk factors associated with unrecognized HIV-1 infection among medical patients presenting to an inner-city emergency department. METHODS: We conducted anonymous HIV-1 testing in subjects interviewed for risk behaviors and knowledge of HIV status at an inner-city ED
Performance characteristics of a rapid HIV antibody assay in a hospital with a high prevalence of HIV infection. CDC-Bronx-Lebanon HIV Serosurvey Team [see comments]: Ann Intern Med. 1996 Sep 15;125(6):471-5. Unique Identifier : AIDSLINE MED/96349972; Irwin K; Olivo N; Schable CA; Weber JT; Janssen R; Ernst J; Centers for Disease Control and Prevention, Atlanta, Georgia,; USA.; BACKGROUND: The delay between collection of blood samples and availability of test results may be as long as 3 weeks and is one barrier to the acceptance of voluntary testing for human immunodeficiency virus (HIV) infection. Serologic tests that provide results rapidly could overcome this barrier, but the accuracy and
Oral manifestations of HIV infection.: Ann Intern Med. 1996 Sep 15;125(6):485-96. Unique Identifier : AIDSLINE MED/96349975; Weinert M; Grimes RM; Lynch DP; University of Texas, Houston Health Science Center, USA.; OBJECTIVE: To provide a comprehensive, literature-based guide to the diagnosis of and the management and referral of patients with oral diseases associated with human immunodeficiency virus (HIV) infection. DATA SOURCES: The literature was reviewed to identify common oral manifestations of HIV infection, the physical
Prophylaxis for occupational exposure to HIV.: Ann Intern Med. 1996 Sep 15;125(6):497-501. Unique Identifier : AIDSLINE MED/96349976; Gerberding JL; San Francisco General Hospital, California, USA.; Effective prophylaxis for infection with the human immunodeficiency virus (HIV) is important for health care providers at risk for exposure to infected blood. The average risk from percutaneous exposure is approximately 0.3%, but exposures involving a high titer of HIV or a large volume of infections material are apt
Rapid testing for HIV antibody: a technology whose time has come [editorial; comment]: Ann Intern Med. 1996 Sep 15;125(6):509-11. Unique Identifier : AIDSLINE MED/96349979; Spielberg F; Kassler WJ
Microsporidia in humans [letter]: Ann Intern Med. 1996 Sep 15;125(6):522-3. Unique Identifier : AIDSLINE MED/96349996; Berg J; Diaz LE; Bender BS
Enteroadherent eaeA-positive Escherichia coli associated with chronic AIDS-related diarrhea [letter]: Ann Intern Med. 1996 Sep 15;125(6):523. Unique Identifier : AIDSLINE MED/96349997; Hii JH; Guccion JG; Gilbert CL
Stability of suramin in aqueous solution; possible implications for the search for suramin metabolites in patients.: Arch Pharm (Weinheim). 1996 May;329(5):225-8. Unique Identifier : AIDSLINE MED/96255522; Kassack M; Nickel P; University of Bonn, Pharmaceutical Institute, Germany.; The stability of an aqueous solution of suramin has been determined. The only degradation product detectable by HPLC was the amine precursor 2. The decomposition kinetics of suramin at different temperatures are shown. Because of first order kinetics the Arrhenius equation could not be used to evaluate the decompositi
Event-related potentials in HIV infection: evidence for impact of antiretroviral treatment [letter]: Arch Neurol. 1996 Aug;53(8):715-6. Unique Identifier : AIDSLINE MED/96326171; Evers S; Husstedt IW; Luttmann S; Bauer B; Grotemeyer KH
Cytomegalovirus infection and colonic perforation in renal transplant patients.: Transpl Int. 1996;9(3):248-51. Unique Identifier : AIDSLINE MED/96298161; Toogood GJ; Gillespie PH; Gujral S; Warren BF; Roake JA; Gray DW; Morris PJ; Oxford Transplant Centre, Headington, Oxford, UK.; Cytomegalovirus ( CMV ) infection in immunocompromised patients is a major cause of morbidity and mortality. A well-documented manifestation of gastrointestinal CMV infection is gastrointestinal haemorrhage. In contrast, CMV-associated intestinal perforation has r
Detection of JC virus DNA in the peripheral blood leukocytes of HIV-infected patients.: AIDS. 1996 Apr;10(4):353-8. Unique Identifier : AIDSLINE MED/96284605; Dubois V; Lafon ME; Ragnaud JM; Pellegrin JL; Damasio F; Baudouin C; Michaud V; Fleury HJ; Department of Virology, Pellegrin Hospital, University of; Bordeaux 2, France.; OBJECTIVES: To assess whether JC virus (JCV) DNA is frequently harboured by peripheral blood leukocytes (PBL) in HIV-positive patients, before the onset of progressive multifocal leukoencephalopathy (PML). DESIGN: The polyomavirus JCV induces PML in immunocompromised persons and particularly AIDS patients. Leukocytes
Rhodococcus equi infection in HIV-infected patients.: AIDS. 1996 Apr;10(4):359-62. Unique Identifier : AIDSLINE MED/96284606; Donisi A; Suardi MG; Casari S; Longo M; Cadeo GP; Carosi G; Clinic of Infectious and Tropical Diseases, University of; Brescia, Italy.; OBJECTIVE: To report clinical and microbiological features and response to treatment in HIV patients with Rhodococcus equi infection. DESIGN: Retrospective study. SETTING: Inpatients admitted to two Infectious Diseases Departments in a community-based hospital. PATIENTS: A total of 12 HIV-positive patients with R. equ
Retention of HIV-1 inside infected MOLT-4 cells in association with adhesion-induced cytoskeleton reorganization.: AIDS. 1996 Apr;10(4):363-8. Unique Identifier : AIDSLINE MED/96284607; Choudhury S; el-Farrash MA; Kuroda MJ; Harada S; Department of Biodefence and Medical Virology, Kumamoto Uiversity; School of Medicine, Japan.; OBJECTIVE: To study the mechanism of the suppression of HIV release during cell-to-cell adhesion. DESIGN AND METHODS: To investigate the effects of cell-to-cell adhesion on HIV release in association with cytoskeletal elements, chronically HIV-infected T cells were cocultured with different adherent cell lines, cultur
Differential activation of the extracellular signal-regulated kinase, Jun kinase and Janus kinase-Stat pathways by oncostatin M and basic fibroblast growth factor in AIDS-derived Kaposi's sarcoma cells.: AIDS. 1996 Apr;10(4):369-78. Unique Identifier : AIDSLINE MED/96284608; Faris M; Ensoli B; Stahl N; Yancopoulos G; Nguyen A; Wang S; Nel AE; Department of Medicine, University of California Los Angles; School of Medicine 90024, USA.; OBJECTIVES: To determine the integration of signalling pathways associated with two recognized Kaposi s sarcoma (KS) growth factors, oncostatin M (OSM) and basic fibroblast growth factor (bFGF), in the induction of KS cell proliferation. DESIGN AND METHODS: We used protein kinase assays, protein-DNA interactions and A
Efficacy of 2-month total parenteral nutrition in AIDS patients: a controlled randomized prospective trial. The French Multicenter Total Parenteral Nutrition Cooperative Group Study.: AIDS. 1996 Apr;10(4):379-84. Unique Identifier : AIDSLINE MED/96284609; Melchior JC; Chastang C; Gelas P; Carbonnel F; Zazzo JF; Boulier A; Cosnes J; Bouletreau P; Messing B; Department of Nutrition, Bichat-Claude Bernard Hospital, Paris,; France.; OBJECTIVE: To evaluate the efficacy of total parenteral nutrition in AIDS patients. DESIGN: A prospective, randomized, controlled, multicentre trial. METHODS: Over a period of 2 months, 31 malnourished and severely immunodepressed AIDS patients were assigned to receive either dietary counselling (n = 15) or home total
The diffuse infiltrative lymphocytosis syndrome. clinical and immunogenetic features in 35 patients.: AIDS. 1996 Apr;10(4):385-91. Unique Identifier : AIDSLINE MED/96284610; Kazi S; Cohen PR; Williams F; Schempp R; Reveille JD; Department of Internal Medicine, University of Texas-Houston; Medical School 77030, USA.; OBJECTIVE: To study the epidemiological, clinical, serological and immunogenetic features of the diffuse infiltrative lymphocytosis syndrome (DILS). DESIGN: Consecutive series of 35 patients with DILS diagnosed from 1992 to 1995 in a cohort of 4100 outpatients infected with HIV-1. METHODS: Thirty-five individuals with
Complications of varicella zoster virus reactivation in HIV-infected homosexual men.: AIDS. 1996 Apr;10(4):393-9. Unique Identifier : AIDSLINE MED/96284611; Veenstra J; van Praag RM; Krol A; Wertheim van Dillen PM; Weigel HM; Schellekens PT; Lange JM; Coutinho RA; van der Meer JT; Department of Public Health and Environment, University of; Amsterdam, The Netherlands.; OBJECT: To study the complication rate of varicella zoster virus (VZV) reactivation and the relationship between complications, presentation and localization of zoster and immune function in HIV disease. DESIGN AND METHODS: A total of 142 episodes of VZV reactivation in 113 out of 544 HIV-1-infected participants in th
Trends in HIV infection among sexually transmitted disease patients in Paris.: AIDS. 1996 Apr;10(4):401-5. Unique Identifier : AIDSLINE MED/96284612; Meyer L; Couturier E; Brossard Y; Janier M; Taquin Y; Mertz JP; Helal H; Bohot JM; Malkin JE; Franceschini P; Brunet JB; Department of Epidemiology, INSERM U292, Bicetre Hospital, Le; Kremlin-Bicetre, France.; OBJECTIVE: To assess trends in HIV infection among sexually transmitted disease (STD) patients. DESIGN: Repeated unlinked anonymous survey, 1991-1993. SETTING: STD clinics in Paris, France . SUBJECTS: Patients (n = 4354) with a new suspected STD. METHODS: HIV antibody testing, using
AIDS: a major health problem among young Italian women.: AIDS. 1996 Apr;10(4):407-11. Unique Identifier : AIDSLINE MED/96284613; Conti S; Lepri AC; Farchi G; Napoli PA; Prati S; Rezza G; Laboratory of Epidemiology and Biostatistics, Istituto Superiore; di Sanita, Rome, Italy.; OBJECTIVE: To estimate the extent of the HIV/AIDS epidemic among Italian women and to assess its impact on mortality. Further, to assess the incidence of AIDS and the main characteristics of women affected by AIDS: with particular attention to those aged 25-34 years, and to identify differences in these characteristic
HIV-1, HIV-2, human papillomavirus infection and cervical neoplasia in high-risk African women.: AIDS. 1996 Apr;10(4):413-7. Unique Identifier : AIDSLINE MED/96284614; Langley CL; Benga-De E; Critchlow CW; Ndoye I; Mbengue-Ly MD; Kuypers J; Woto-Gaye G; Mboup S; Bergeron C; Holmes KK; Kiviat NB; Department of Medicine, University of Washington, Seattle, USA.; OBJECTIVE: To determine the effect of HIV-1 and HIV-2 infection on the prevalence of cervical human papillomavirus (HPV) and squamous intraepithelial lesions (SIL) in a population of high-risk women in Senegal . DESIGN AND PARTICIPANTS: Cross-sectional study among 759 female commer
Progression of HIV: follow-up of Edinburgh injecting drug users with narrow seroconversion intervals in 1983-1985.: AIDS. 1996 Apr;10(4):419-30. Unique Identifier : AIDSLINE MED/96284615; Brettle RP; McNeil AJ; Burns S; Gore SM; Bird AG; Yap PL; MacCallum L; Leen CS; Richardson AM; Regional Infectious Disease Unit, City Hospital, Edinburgh, UK.; OBJECTIVE: To describe progression and survival of individuals infected with HIV by injecting drug use in Edinburgh. DESIGN AND METHODS: From 313 HIV-infected patients with retrospectively estimated narrow seroconversion intervals, 260 infected via injecting drug use in the years 1983-1985 were selected for the study
The Edinburgh cohort of HIV-positive injecting drug users at 10 years after infection: a case-control study of the evolution of dementia.: AIDS. 1996 Apr;10(4):431-40. Unique Identifier : AIDSLINE MED/96284616; Goodwin GM; Pretsell DO; Chiswick A; Egan V; Brettle RP; University Department of Psychiatry, Royal Edinburgh Hospital,; UK.; OBJECTIVE: To examine the evolution of dementia in HIV-positive injecting drug users (IDU) in Edinburgh. DESIGN: Case-control study. PARTICIPANTS: Twenty six (6%) out of 404 patients in the Edinburgh cohort of HIV-positive IDU who have developed HIV-1-associated dementia in the 10
Similarity between Nef of primate lentiviruses and p15E of murine and feline leukaemia viruses [letter]: AIDS. 1996 Apr;10(4):441-2. Unique Identifier : AIDSLINE MED/96284617; Collette Y; Dutartre H; Benziane A; Olive D
Detection of Isospora in the stools of AIDS patients using a new rapid autofluorescence technique [letter]: AIDS. 1996 Apr;10(4):442-3. Unique Identifier : AIDSLINE MED/96284618; Berlin OG; Conteas CN; Sowerby TM
Testing and management of Toxoplasma serology in HIV-seropositive patients [letter]: AIDS. 1996 Apr;10(4):443-4. Unique Identifier : AIDSLINE MED/96284619; Aarons E; Hawkins D; Nelson M; Gazzard B
The occurrence of Blastocystis hominis in HIV-infected patients [letter]: AIDS. 1996 Apr;10(4):444-5. Unique Identifier : AIDSLINE MED/96284620; Storgaard M; Lauren AL; Anderson PL
Condom use in clients of prostitutes in Spain [letter]: AIDS. 1996 Apr;10(4):445-6. Unique Identifier : AIDSLINE MED/96284621; Estebanez P; Rua-Figueroa M; Aguilar MD; Bru F; Rog Emilio Zunzunegui MV
Lack of utility of routine chest radiographs in HIV-infected patients [letter]: AIDS. 1996 Apr;10(4):446-7. Unique Identifier : AIDSLINE MED/96284622; Olson PE; Wallace MR; Grillo MP; Rossetti RJ; Miller LK
Antiplatelet antibodies during the course of HIV-preventive vaccine trial [letter]: AIDS. 1996 Apr;10(4):447-9. Unique Identifier : AIDSLINE MED/96284623; Kaplan C; Morel-Kopp MC; Kieny MP; Kolbe H; Salmon P; Sicard D; Pialoux G; Meignier B; Excler JL; Plotkin S
CD4 count in HIV infection is positively correlated to interferon-gamma and negatively correlated to interleukin-10 in vitro production [letter]: AIDS. 1996 Apr;10(4):449-51. Unique Identifier : AIDSLINE MED/96284624; Salvaggio A; Balotta C; Galli M; Clerici M
Serum nitrite concentration suggests a role for nitric oxide in AIDS [letter]: AIDS. 1996 Apr;10(4):451-2. Unique Identifier : AIDSLINE MED/96284625; Baldeweg T; Sooranna S; Das I; Catalan J; Gazzard B
Interest and reliability of a polymerase chain reaction on bone-marrow samples in the diagnosis of visceral leishmaniasis in AIDS [letter]: AIDS. 1996 Apr;10(4):452-3. Unique Identifier : AIDSLINE MED/96284626; Piarroux R; Gambarelli F; Toga B; Dumon H; Fontes M; Dunan S; Quilici M
AIDS in Cote d'Ivoire--ten years on.: J Public Health Med. 1996 Mar;18(1):107-11. Unique Identifier : AIDSLINE MED/96260825; Watson P; Snell P; Hopital Protestant de Dabou et Fondation Protestante pour la; Sante, Cote d'Ivoire.; AIDS is a world-wide health problem with a profile which varies widely. Cote d Ivoire is one of the hardest hit countries in Africa. Since the declaration of the first cases in 1985, more than 18 600 cases have been diagnosed. Many initiatives have already been undertaken in t
Dentists practising in Lothian treat HIV seropositive patients: is this a resolution of conflict or a case of Hobson's choice?: Br Dent J. 1996 Jan 20;180(2):53-6. Unique Identifier : AIDSLINE MED/96274067; Gibson BJ; Freeman R; Division of Paediatric and Preventive Dentistry, Queen's; University of Belfast.; Dentists are now required to treat HIV-positive patients in their practices. Dentists working in high HIV prevalence areas treat HIV seropositive patients but what affects this treatment decision? The aim of this study is to investigate the role of conflict with regard to treatment decisions. All 371 dentists practisi
Most sexually active teenagers would have unprotected sex [news]: Nurs Stand. 1996 Jul 10;10(42):9. Unique Identifier : AIDSLINE MED/96364890
A randomized study comparing the effect of GM-CSF and G-CSF on immune reconstitution after autologous bone marrow transplantation.: Br J Haematol. 1996 Jul;94(1):140-7. Unique Identifier : AIDSLINE MED/96301241; San Miguel JF; Hernandez MD; Gonzalez M; Lopez-Berges MC; Caballero MD; Vazquez L; Orfao A; Nieto MJ; Corral M; del Canizo MC; Department of Haematology, University Hospital of Salamanca,; University of Salamanca, Spain.; Haemopoietic growth factors (HGFs) have been shown to accelerate recovery from severe neutropenia after autologous bone marrow transplantation (ABMT) but their effect on immune reconstitution is not well defined. The present study compares, through randomized trial, the in vivo effect of GM-CSF and G-CSF administratio
Investigation of chronic hepatitis C infection in individuals with haemophilia: assessment of invasive and non-invasive methods.: Br J Haematol. 1996 Jul;94(1):159-65. Unique Identifier : AIDSLINE MED/96301244; Hanley JP; Jarvis LM; Andrews J; Dennis R; Lee R; Simmonds P; Piris J; Hayes P; Ludlam CA; Department of Haematology, Royal Infirmary of Edinburgh.; Hepatitis C virus (HCV) infection is the major cause of chronic liver disease in individuals with haemophilia. A wide spectrum of disease severity is found in this group, ranging from mild hepatitis to cirrhosis. We have studied a cohort of 87 anti-HCV positive haemophiliacs who have been infected with HCV for 10-25 y
Secretory component (polymeric immunoglobulin receptor) expression on human keratinocytes by stimulation with interferon-gamma and differences in response.: J Dermatol Sci. 1996 Mar;11(3):214-22. Unique Identifier : AIDSLINE MED/96235500; Nihei Y; Maruyama K; Endo Y; Sato T; Kobayashi K; Kaneko F; Department of Dermatology, Fukushima Medical College, Japan.; Secretory IgA (sIgA) is a major protective factor in the mucosal immune system because of its great ability to form complexes with bacteria. Secretory component (SC) is an 80-kDa glycoprotein, a component of sIgA, which functions as a polymeric immunoglobulin receptor for IgA and aids the secretion of sIgA from the ep
Oxymetholone promotes weight gain in patients with advanced human immunodeficiency virus (HIV-1) infection.: Br J Nutr. 1996 Jan;75(1):129-38. Unique Identifier : AIDSLINE MED/96246078; Hengge UR; Baumann M; Maleba R; Brockmeyer NH; Goos M; Department of Dermatology, University of Essen, Germany.; The effect of the testosterone derivative oxymetholone alone or in combination with the H1-receptor antagonist ketotifen, which has recently been shown to block tumour necrosis factor alpha (TNF alpha), on weight gain and performance status in human immunodeficiency virus (HIV) patients with chronic cachexia was evalu
Successful adherence to observed prophylaxis and treatment of tuberculosis among drug users in a methadone program.: J Addict Dis. 1996;15(1):93-104. Unique Identifier : AIDSLINE MED/96308538; Gourevitch MN; Wasserman W; Panero MS; Selwyn PA; Department of Epidemiology and Social Medicine, Albert Einstein; College of Medicine, Bronx, NY 10467, USA.; Incomplete antituberculous chemoprophylaxis and treatment are major causes of the resurgence of tuberculosis, often drug-resistant, among drug users. We offered directly observed antituberculous chemoprophylaxis (n = 102) or treatment (n = 12) to tuberculous chemoprophylaxis (n = 102) or treatment (n = 12) to eligible
Stability of drug additives to peritoneal dialysate.: Perit Dial Int. 1995 Oct-Dec;15(8):328-35. Unique Identifier : AIDSLINE MED/96241096; Bailie GR; Kane MP; Department of Pharmacy Practice, Albany College of Pharmacy, New; York 12208, USA.; OBJECTIVE: The primary literature was reviewed to determine the stability of drug additives in peritoneal dialysis solutions. DATA SOURCES: A MEDLINE search and retrieval, covering the period 1981 to 1994, was undertaken to identify relevant original literature. Additional references were identified from citations wit
Rifabutin prophylaxis for Mycobacterium avium complex infection in patients with AIDS.: Clin Infect Dis. 1996 Apr;22 Suppl 1:S23-30; discussion S30-2. Unique Identifier : AIDSLINE MED/96250349; Siegal FP; Albert Einstein College of Medicine, New Hyde Park, New York,; USA.; Rifabutin, a macrophage-penetrating lipophilic rifamycin, has a long half-life and activity in vitro against Mycobacterium avium complex (MAC). Preliminary studies of patients with AIDS and those with AIDS-related complex defined dose-limiting toxic effects (arthralgia/arthritis and uveitis) and suggested that rifabut
Rifabutin in the treatment of Mycobacterium avium complex infection: experience in Europe.: Clin Infect Dis. 1996 Apr;22 Suppl 1:S33-6. Unique Identifier : AIDSLINE MED/96250350; Dautzenberg B; Centre Hospitalo-Universitaire Pitie Salpetriere, Paris,; France.; Several European clinical trials of rifabutin alone or in multidrug regimens for treatment of infections due to Mycobacterium avium complex (MAC) in patients with AIDS are discussed. A prospective open study in France assessed 50 patients treated with the combination rifabutin/ iso
Mycobacterium avium complex infection, rifabutin, and uveitis--is there a connection?: Clin Infect Dis. 1996 Apr;22 Suppl 1:S43-7; discussion S47-9. Unique Identifier : AIDSLINE MED/96250352; Nichols CW; Department of Ophthalmology, School of Medicine, University of; Pennsylvania Medical Center, Philadelphia, USA.; Rifabutin, an antimycobacterial agent, has been recommended by the U.S. Public Health Service as prophylaxis against infection due to Mycobacterium avium complex (MAC) in patients with AIDS. When rifabutin is administered as prophylaxis, uveitis has been reported only rarely. However, uveitis has been reported in two
Use of rifabutin in the treatment of pulmonary tuberculosis.: Clin Infect Dis. 1996 Apr;22 Suppl 1:S50-4. Unique Identifier : AIDSLINE MED/96250353; Grassi C; Peona V; Respiratory Diseases Clinic, Pavia, Italy.; This article reviews recent studies conducted outside the United States assessing the efficacy and safety of rifabutin in the treatment of tuberculosis (TB) in HIV-infected patients, in patients with newly diagnosed TB, and in patients with multidrug-resistant TB. A 6-month pilot study
Prophylaxis for tuberculosis in Europe--ongoing research.: Clin Infect Dis. 1996 Apr;22 Suppl 1:S55-60. Unique Identifier : AIDSLINE MED/96250354; Carosi G; Matteelli A; Clinic of Infectious and Tropical Diseases, University of; Brescia, Italy.; The incidence of tuberculosis (TB) in patients with human immunodeficiency virus (HIV) infection has increased in recent years, raising issues regarding preventive therapy for TB in this high-risk patient population. To determine if an HIV-positive individual is at risk for reactivation of latent infection, testing wi
Potential role of rifabutin in prophylaxis for tuberculosis and infections due to multiple opportunistic pathogens.: Clin Infect Dis. 1996 Apr;22 Suppl 1:S61-6; discussion S66-9. Unique Identifier : AIDSLINE MED/96250355; Chaisson RE; Department of Medicine, Johns Hopkins University, Baltimore,; Maryland 21287-6220, USA.; Patients with advanced human immunodeficiency virus (HIV) disease are at risk for infections caused by protozoa, fungi, viruses, bacteria, and mycobacteria. Chemoprophylaxis is being used increasingly to prevent a growing number of opportunistic infections that occur in HIV-infected patients. Multiple opportunistic pa
[Innovative processes in ambulatory care--AIDS as a pilot project]: Pflege. 1996 Jun;9(2):140-9. Unique Identifier : AIDSLINE MED/96361160; Schaeffer D; Flexibility in nursing practice and the willingness to be innovative are discussed, using the care of patients with AIDS as an example. When this new infectious disorder made its first appearance many countries tried to provide a patient-centred, community based service, in spite of the severity of the illness and the
[Adenosine deaminase (ADA) and beta 2-microglobulin (beta 2M) as discriminating serum markers of progression to AIDS]: An Med Interna. 1996 May;13(5):217-21. Unique Identifier : AIDSLINE MED/96300663; Perez de Oteyza C; Menendez Martinez MA; Irazabal C; Enriquez de Salamanca R; Perez Aznar C; Rebollar JL; Departamento de Medicina Interna, Hospital Militar Universitario; Gomez Ulla, Universidad Complutense, Madrid.; BACKGROUND: To establish the discriminatory value of ADA and beta 2M serum levels as markers of AIDS progression. METHODS: We have followed quarterly during two years a cohort of 24 patients with HIV infection; 103 clinical and laboratory evaluations were done (CDC/93 classification). In each of those blood samples we
[Applications of the polymerase chain reaction (PCR) to the diagnosis of central nervous system infections]: An Med Interna. 1996 May;13(5):235-8. Unique Identifier : AIDSLINE MED/96300667; Querol JM; Farga A; Alonso C; Granda D; Alcaraz MJ; Garcia de Lomas J; Servicio de Medicina Interna, Hospital Lluis Alcanyis, Xativa.; The utility of polymerase chain reaction (PCR) is described for the diagnosis in three patients suffering from central nervous system infections, tuberculous meningitis, herpetic encephalitis and cerebral toxoplasmosis. PCR was performed in the cerebrospinal fluid after processing the specimen by two methods, proteina
[The development of a test for evaluating the knowledge of and attitudes on human immunodeficiency virus infection in primary health care professionals]: Aten Primaria. 1996 May 31;17(9):564-9. Unique Identifier : AIDSLINE MED/96294337; Llobera Serentill A; Casabella Abril B; Perez Sanchez J; Carrillo Munoz R; Via Vidal M; Garcia Ortega D; Unidad Psicologia Medica, Facultad de Medicina, Universidad; Autonoma, Barcelona.; OBJECTIVE. To compose both a multiple choice test (MCT) to evaluate primary care professionals understanding of HIV infection and a scale to measure their attitudes towards it. DESIGN. Validation of questionnaires. SETTING. Ciutat Vella health district (City of Barcelona) and university teaching hospitals in Barcelon
Setting the stage for predicting RNA thermodynamic properties and their structural components.: Biophys J. 1996 Apr;70(4):1571-2. Unique Identifier : AIDSLINE MED/96248259; Broyde S; Biology Department, New York University, New York 10003, USA.
Design and synthesis of substrate-based peptidomimetic human immunodeficiency virus protease inhibitors containing the hydroxymethylcarbonyl isostere.: Biopolymers. 1996;40(2):235-44. Unique Identifier : AIDSLINE MED/96232640; Kiso Y; Department of Medicinal Chemistry, Kyoto Pharmaceutical; University, Japan.; The human immunodeficiency (HIV) codes for an aspartic protease known to be essential for retroviral maturation and replication. The HIV protease can recognize Phe-Pro and Tyr-Pro sequences as the virus-specific cleavage site. These features provided a basis for the rational design of selective HIV protease-targeted d
Safety and immunogenicity of Staphylococcus aureus type 5 capsular polysaccharide-Pseudomonas aeruginosa recombinant exoprotein A conjugate vaccine in patients on hemodialysis.: J Am Soc Nephrol. 1996 Feb;7(2):247-53. Unique Identifier : AIDSLINE MED/96265507; Welch PG; Fattom A; Moore J Jr; Schneerson R; Shiloach J; Bryla DA; Li X; Robbins JB; Nephrology Service, Walter Reed Army Medical Center, Washington,; DC, USA.; Seventeen volunteers with ESRD on hemodialysis, negative for infection with HIV or hepatitis B and C and not receiving immunosuppressive therapy, were injected two times 6 wk apart with 25 micrograms of Staphylococcus aureus Type 5 capsular polysaccharide-Pseudomonas aeruginosa exoprotein A (rEPA) conjugate. Controls
The road in and out of homelessness: perceptions of recovering substance abusers.: J Assoc Nurses AIDS Care. 1995 Sep-Oct;6(5):11-9. Unique Identifier : AIDSLINE MED/96111431; Moneyham L; Connor A; Nell Hodgson Woodruff School of Nursing, Emory University,; Atlanta, GA, USA.; In this phenomenological study the authors explored the meaning of homelessness from the perspective of previously homeless substance abusers. The sample involved 8 adult males recruited from a substance abuse treatment program. Through the use of open-ended questioning, two major themes were identified: the road to h
Satisfaction with home healthcare services for clients with HIV: preliminary findings.: J Assoc Nurses AIDS Care. 1995 Sep-Oct;6(5):20-5. Unique Identifier : AIDSLINE MED/96111432; Foley ME; Fahs MC; Eisenhandler J; Hyer K; Department of Community Medicine, Mount Sinai School of Medicine,; New York, New York, USA.; The Visiting Nurse Service of New York and Empire Blue Cross and Blue Shield implemented in 1990 the At Home Options Program (AHOP), an enhanced package of home care and other noninpatient services for HIV-positive clients. AHOP aims to reduce total treatment costs and hospital days. Clients (N = 52) completed mailed
New perspectives on HIV pathogenesis. Viral replication is continuous throughout the course of disease.: J Assoc Nurses AIDS Care. 1995 Sep-Oct;6(5):26-7. Unique Identifier : AIDSLINE MED/96111433
Health locus of control among HIV-positive indigent women.: J Assoc Nurses AIDS Care. 1995 Sep-Oct;6(5):29-36. Unique Identifier : AIDSLINE MED/96111434; Ragsdale D; Kotarba JA; Morrow JR Jr; Yarbrough S; Texas Woman's University, Houston, USA.; The authors explored the multidimensional construct of health locus of control among 14 indigent HIV-positive women who attended one of two southwestern city health clinics. An exploratory survey design was used to compare the mean responses of the subjects on the Multidimensional Health Locus of Control (MHLC) Scales
Mycobacterium avium complex infection in AIDS: clinical features, treatment, and prevention.: J Assoc Nurses AIDS Care. 1995 Sep-Oct;6(5):37-47; quiz 48-9. Unique Identifier : AIDSLINE MED/96111435; Eccles E; Ptak J; Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.; Infection with Mycobacterium avium complex (MAC) may cause a serious disseminated bacterial infection in up to 40% of patients with advanced HIV infection. Disseminated MAC has a negative impact on quality of life and contributes significantly to morbidity and mortality. Prompt diagnosis and aggressive treatment can d
Zerit.: J Assoc Nurses AIDS Care. 1995 Sep-Oct;6(5):50-2. Unique Identifier : AIDSLINE MED/96111436; Porche DJ; Nicholls State University, Thibodaux, LA, USA.
The elderly: the silent population [editorial]: J Assoc Nurses AIDS Care. 1995 Sep-Oct;6(5):9-10. Unique Identifier : AIDSLINE MED/96111430; Gueldner SH
Adult T-cell leukemia: challenge for induction of apoptosis in leukemic cells [editorial; comment]: Intern Med. 1996 Mar;35(3):167-8. Unique Identifier : AIDSLINE MED/96258889; Suzushima H; Yamaguchi K
13-cis retinoic acid inhibits growth of adult T cell leukemia cells and causes apoptosis; possible new indication for retinoid therapy [see comments]: Intern Med. 1996 Mar;35(3):180-4. Unique Identifier : AIDSLINE MED/96258893; Maeda Y; Miyatake J; Sono H; Matsuda M; Tatsumi Y; Horiuchi F; Irimajiri K; Horiuchi A; Third Department of Internal Medicine, Kinki University School of; Medicine, Osaka.; We evaluated the effects of 13-cis retinoic acid (13-cis RA) on the growth of peripheral blood mononuclear cells (PBMC) obtained from 12 patients with adult T cell leukemia (ATL). In general, 13-cis RA potently inhibited the growth of PBMC from ATL patients. However, the sensitivity of the cells to 13-cis RA-induced g
Spontaneous proliferation of and cytokine production by T cells adherent to human endothelial cells in patients with human T-lymphotropic virus type I-associated myelopathy.: Intern Med. 1996 Mar;35(3):195-9. Unique Identifier : AIDSLINE MED/96258896; Nakamura T; Nishiura Y; Ichinose K; Shirabe S; Tsujino A; Goto H; Furuya T; Nagataki S; First Department of Internal Medicine, Nagasaki University School; of Medicine.; We previously reported increased adherence of T cells to human endothelial cells (EC) in patients with HTLV-I-associated myelopathy (HAM). To define the immunological function of EC-adherent T cells from HAM patients, we investigated the degree of spontaneous proliferation and the production of inflammatory cytokines,
[Vitreous involvement in cytomegalovirus retinitis]: Ophthalmologe. 1995 Oct;92(5):685-6. Unique Identifier : AIDSLINE MED/96348264; Richter R; Gumbel H; Muller HM; Fries U; Rodenbach M; Ohrloff C; Zentrum der Augenheilkunde, Universitatsklinikum Frankfurt/M.; In our outpatient department we often see patients with vitreous inflammation. Recent reports emphasize that vitreous inflammation is very rare, so we looked for patients with cytomegalovirus ( CMV ) retinitis and vitreous infl
Ethics: a matter of judgment.: Trends Health Care Law Ethics. 1995 Fall;10(4):15-6, 40. Unique Identifier : AIDSLINE MED/96334690; Cassidy RC
New York State to give mothers the right to HIV test results [news]: Trends Health Care Law Ethics. 1995 Fall;10(4):6. Unique Identifier : AIDSLINE MED/96334688; Stolman CJ
Combination drug treatment benefits patients with HIV [news]: BMJ. 1996 Aug 10;313(7053):320. Unique Identifier : AIDSLINE MED/96343740; Boulton A
Fluctuations of HIV load in semen of HIV positive patients with newly acquired sexually transmitted diseases.: BMJ. 1996 Aug 10;313(7053):341-2. Unique Identifier : AIDSLINE MED/96343747; Atkins MC; Carlin EM; Emery VC; Griffiths PD; Boag F; Department of Virology, Royal Free Hospital School of Medicine,; London.
PBPC grafts from healthy donors: analysis of CD34+ and CD3+ subpopulations.: Bone Marrow Transplant. 1996 Mar;17 Suppl 2:S22-7. Unique Identifier : AIDSLINE MED/96291504; Dreger P; Oberboster K; Schmitz N; Second Dept. of Medicine, University of Kiel, Germany.
Enrichment of allogeneic CD34+ cells and T cell depletion by percoll density gradient centrifugation.: Bone Marrow Transplant. 1996 Mar;17 Suppl 2:S31-3. Unique Identifier : AIDSLINE MED/96291506; Negrin RS; Kusnierz-Glaz C; Blume KG; Strober S; Stanford University, California, USA.
Antibodies reactive with HIV-1 antigens in systemic lupus erythematosus.: Lupus. 1996 Apr;5(2):120-2. Unique Identifier : AIDSLINE MED/96292511; Gul A; Inanc M; Yilmaz G; Ocal L; Konice M; Aral O; Badur S; Dilsen N; Department of Internal Medicine, Istanbul Faculty of Medicine,; University of Istanbul, Turkey.; Antibodies reactive with retroviral gag proteins have been detected in patients with systemic lupus erythematosus (SLE). We investigated the immune responses against human immunodeficiency virus (HIV) 1 antigens in the sera of 44 Turkish patients with SLE. Serum samples were tested by using two different commercial en
[Upper genital tract infections in women infected with HIV: epidemiologic, diagnostic and therapeutic aspects]: Contracept Fertil Sex. 1996 Jun;24(6):488-94. Unique Identifier : AIDSLINE MED/96327279; Panel P; Benifla JL; Darai E; Renolleau C; Sebban E; Waschowska B; Madelenat P; Service de Gynecologie-Obstetrique, CHU Bichat-Claude-Bernard,; Paris.; Fifty seven women hospitalized in the gynecological department of Bichat-Claude Bernard hospital in Paris for pelvic inflammatory disease (PID) proven by laparoscopy from sept. 1992 to nov. 1994 had a serological diagnosis of HIV infection. Three of them (5,2%) were positive (HIV+). Previous publications have shown fr
Conflicts in the biotechnology industry.: J Law Med Ethics. 1995 Winter;23(4):354-9. Unique Identifier : AIDSLINE MED/96334410; Greely HT
Legislating privacy: the HIV experience.: J Law Med Ethics. 1995 Winter;23(4):371-4. Unique Identifier : AIDSLINE MED/96334413; Parmet WE
Why the use of anonymous samples for research matters.: J Law Med Ethics. 1995 Winter;23(4):375-7. Unique Identifier : AIDSLINE MED/96334414; Clayton EW
Ethical issues raised by needle exchange programs.: J Law Med Ethics. 1995 Winter;23(4):382-8. Unique Identifier : AIDSLINE MED/96334416; Loue S; Lurie P; Lloyd LS
[Sickle cell anemia in the south of Zaire. Study of two series of 251 and 340 patients followed-up 1988-1992]: Arch Pediatr. 1996 Feb;3(2):104-11. Unique Identifier : AIDSLINE MED/96241293; Tshilolo L; Mukendi R; Girot R; Service de pediatrie, hopital Gecamines, Kolwesi, Zaire.; BACKGROUND: This work concerns 591 sickle cell disease patients followed by the same paediatrics team in south Zaire . POPULATION: Two series of homozygous sickle cell patients were studied: 1) 251 in-patients hospitalized in Kolwezi during the period 1988-1989, and 2) 340 out-pati
[Role of HIV infection in the pathology of infants and young children in Brazzaville (letter)]: Arch Pediatr. 1996 Feb;3(2):186-7. Unique Identifier : AIDSLINE MED/96241311; Senga P; Mouko A; Makuwa M
[Maternal-fetal HIV infection diagnosed in a 12 year-old child (letter)]: Arch Pediatr. 1996 Mar;3(3):290-1. Unique Identifier : AIDSLINE MED/96263551; Dageville C; Benmouloud M; Haas H; Monpoux F; Cottalorda J; Mariani R
Neuro-ophthalmology and systemic disease--Part II. An annual review (1994).: J Neuroophthalmol. 1995 Dec;15(4):241-53. Unique Identifier : AIDSLINE MED/96357915; Newman NJ; Department of Ophthalmology, Emory University School of Medicine,; Atlanta, Georgia, USA.
[The care of patients with AIDS]: Pflege Aktuell. 1996 Feb;50(2):120-4. Unique Identifier : AIDSLINE MED/96329292; Steven B
Polyarteritis nodosa in human immunodeficiency virus infection: report of four cases and review of the literature.: Br J Rheumatol. 1996 Aug;35(8):796-9. Unique Identifier : AIDSLINE MED/96350184; Font C; Miro O; Pedrol E; Masanes F; Coll-Vinent B; Casademont J; Cid MC; Grau JM; Serrei de Medicina Interna General, Hospital Clinic i Provincial,; Universitat de Barcelona, Spain.; Four patients with HIV infection were diagnosed as having panarteritis nodosa type vasculitis in muscle samples taken by biopsy. Fever, weight loss and neuromuscular symptoms were the major complaints. All but one were successfully treated with a low dose of prednisone. The other patient refused treatment, but her mus
Evidence of HTLV-I in thyroid tissue in an HTLV-I carrier with Hashimoto's thyroiditis.: J Mol Med. 1996 May;74(5):275-78. Unique Identifier : AIDSLINE MED/96369258; Kawai H; Mitsui T; Yokoi K; Akaike M; Hirose K; Hizawa K; Saito S; First Department of Internal Medicine, School of Medicine,; University of Tokushima, Japan.; Human T-lymphotropic virus type l (HTLV-I) protein and messenger RNA (mRNA) for HTLV-I were examined in thyroid tissues from two patients with Hashimoto s thyroiditis and serum anti-thyroid antibody. The virus envelope protein and signals for the mRNA were detected in many of the follicular epithelial cells of the thy
HIV genome transcription induced by polyoma virus middle T antigen through both enhancer- and promoter-dependent LTR activation.: C R Acad Sci III. 1995 Dec;318(12):1227-32. Unique Identifier : AIDSLINE MED/96306659; Jacque JM; Vlach J; Virelizier JL; Garcia A; Unite d'immunologie virale, Institut Pasteur, Paris, France.; In order to understand the regulation of HIV genome transcription induced by cell stimulation through transmembrane receptors, we have transfected cells with polyoma middle T antigen (PyMT) expression vectors, thus mimicking activated receptor-dependent cell stimulation. PyMT-expressing Cos7 cells provided an environm
[Evaluation of the antiradical protector effect of multifermented milk serum with reiterated dosage in rats]: C R Seances Soc Biol Fil. 1995;189(6):1191-7. Unique Identifier : AIDSLINE MED/96307127; Stella V; Postaire E; Direction Scientifique, Pharmacie Centrale des Hopitaux, Paris.; Epidemiological and experimental studies suggest that dietary milk products may exert an inhibitory effect on the development of several types of tumors. Some recent experiments in rodents indicate that the antitumor activity of the dairy product is in the protein fraction and more specifically in the whey protein com
Dental care of patients who receive head and neck radiation therapy [letter]: Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1996 May;81(5):506-7. Unique Identifier : AIDSLINE MED/96322501; Epstein JB; Stevenson-Moore P
Nurses/midwives call for more HIV/AIDS protection [news]: Midwives. 1995 Dec;108(1295):401. Unique Identifier : AIDSLINE MED/96334512
Infant nutrition perspectives.: Midwives. 1996 May;109(1300):120. Unique Identifier : AIDSLINE MED/96364803; Stevens T
Irradiation of singly and doubly transduced murine neuroblastoma cells expressing B7-1 and producing interferon-gamma reduces their capacity to induce systemic immunity.: Cancer Gene Ther. 1996 Mar-Apr;3(2):75-82. Unique Identifier : AIDSLINE MED/96280238; Katsanis E; Bausero MA; Panoskaltsis-Mortari A; Dancisak BB; Xu Z; Orchard PJ; Davis CG; Blazar BR; Department of Pediatrics, University of Minnesota, Minneapolis; 55455, USA.; We have previously reported that immunization with low major histocompatibility complex (MHC) class I expressing murine neuroblastoma (neuro-2a) transduced with B7-1 fails to induce significant protection to wild-type tumor challenge. In this study we investigated whether B7-1 expressing neuro-2a cells can stimulate a
Prodrug-activated gene therapy: involvement of an immunological component in the bystander effect.: Cancer Gene Ther. 1996 Mar-Apr;3(2):83-8. Unique Identifier : AIDSLINE MED/96280239; Gagandeep S; Brew R; Green B; Christmas SE; Klatzmann D; Poston GJ; Kinsella AR; Department of Surgery, Royal Liverpool University Hospital,; England.; The integration and expression of the herpes simplex virus type 1 thymidine kinase (HSV1-TK) gene in localized tumors results in tumor regression after the administration of the specific nucleoside analogue ganciclovir (GCV). Although only 10% to 20% of the tumor cells take up the HSV1-TK gene, the neighboring cells a
Absent inhibition of hepatitis B virus replication by azidothymidine in patients chronically coinfected by HIV-1 and HBV.: New Microbiol. 1996 Apr;19(2):167-9. Unique Identifier : AIDSLINE MED/96332680; Gallian P; De Lamballerie X; Lehucher MP; Dhiver C; Ravaux I; Laboratoire de Virologie de l'Assistance Publique de Marseille,; Hopital de la Timone, Marseille.; The effect of Azidothymidine ( AZT ) in vivo on the replication of the Hepatitis B Virus (HBV) was studied in a population of 25 patients chronically coinfected by HBV and Human Immunodeficiency Virus Type 1 (HIV-1), and receiving AZT at the usual dosag
Geographic differences in the attitudes, knowledge and infection control practices of Ontario dentists.: Can J Public Health. 1996 Mar-Apr;87(2):119-24. Unique Identifier : AIDSLINE MED/96321417; McCarthy GM; Koval JJ; MacDonald JK; Faculty of Dentistry, University of Western Ontario, London.; Geographic differences in the HIV related attitudes, knowledge and behaviours of 5,997 dentists in Ontario were investigated using mailed questionnaires (response rate 70%). Proportionately more respondents from larger population centres reported that they knowingly treated HIV-infected patients (p
[Health, social life and sexuality]: Can Nurse. 1995 Nov;91(10):17. Unique Identifier : AIDSLINE MED/96345276; This research study looked at the health, social life and sexuality of a portion of the University of Montreal student population. More than 600 resident and non-resident students in the 18-26 age group were interviewed by the authors in an attempt to better define prevention strategies in the battle against AIDS and
Reducing the occupational risk of TB.: Can Nurse. 1995 Nov;91(10):27-31. Unique Identifier : AIDSLINE MED/96345281; Stringer B; Tuberculosis, an infectious disease caused by the micro-organism Mycobacterium tuberculosis, has wrought devastation for centuries. According to estimates, in the 1800s alone, say estimates, it was responsible for almost one-third of the deaths in Europe. In the 20th century, the incidence of TB declined dramatically
Tuberculosis: the threat lingers.: Can Nurse. 1995 Nov;91(10):33-7. Unique Identifier : AIDSLINE MED/96345282; Lloyd N; Worldwide, tuberculosis has reached epidemic proportions. An estimated one-third of the world s population is infected with the disease. It kills three million people each year, and more adults die from TB than from any other infectious disease. In April 1993, The World Health Organization
An oasis of health for poor or homeless people who are HIV-positive.: Can Nurse. 1996 Mar;92(3):16-7. Unique Identifier : AIDSLINE MED/96337577; Sibbald BJ
Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection.: Cell. 1996 Aug 9;86(3):367-77. Unique Identifier : AIDSLINE MED/96339434; Liu R; Paxton WA; Choe S; Ceradini D; Martin SR; Horuk R; MacDonald ME; Stuhlmann H; Koup RA; Landau NR; Aaron Diamond AIDS Research Center, Rockefeller University New; York, New York 10016, USA.; Rare individuals have been multiply exposed to HIV-1 but remain uninfected. The CD4+ T-cells of two of these individuals, designated EU2 and EU3, are highly resistant in vitro to the entry of primary macrophagetropic virus but are readily infectable with transformed T-cell line adapted viruses. We report here on the g
Expression of functional HIV-1 integrase in the yeast Saccharomyces cerevisiae leads to the emergence of a lethal phenotype: potential use for inhibitor screening.: Curr Genet. 1996 May;29(6):503-10. Unique Identifier : AIDSLINE MED/96269908; Caumont AB; Jamieson GA; Pichuantes S; Nguyen AT; Litvak S; Dupont C; IBGC-CNRS, Laboratoire de Replication et Expression des Genomes; Eucaryotes et Retroviraux, 1 rue Camille St Saens, F-33077; Bordeaux-Cedex, France.; The integrase of the human immunodeficiency virus type 1 (HIV-1) has been expressed in yeast in order to investigate its potential lethal effect mediated by DNA damage. To this end, we have constructed an expression plasmid containing the retroviral integrase gene under the control of the inducible promotor ADH2/GAPDH
Tuberculosis and HIV infection.: Ceylon Med J. 1996 Mar;41(1):5-6. Unique Identifier : AIDSLINE MED/96321431; Uragoda CG
Psoriatic arthritis.: Dermatol Clin. 1995 Oct;13(4):779-92. Unique Identifier : AIDSLINE MED/96241043; Winchester R; Department of Pediatrics, Columbia University, New York, NY; 10032, USA.; Psoriatic arthritis and its associated enthesopathy appear to be another immune-mediated manifestation of the genetic predisposition to develop psoriasis. The occurrence of psoriatic arthritis in the setting of the selective immune deficiency of advanced HIV infection, especially in the association with HLA-B27, point
Serological investigation of HIV-1 variant subtype strains in transmission in Nairobi.: East Afr Med J. 1996 Feb;73(2):88-90. Unique Identifier : AIDSLINE MED/96349641; Songok EM; Tukei PM; Mulaa FJ; Virus Research Centre, Kenya Medical Research Institute, Nairobi,; Kenya.; In a bid to determine the HIV-1 subtype variants in transmission in Nairobi and its possible association with clinical status, we screened 207 confirmed HIV-1 positive patients visiting HIV/AIDS laboratory at the Virus Research Centre in Nairobi between January and March 1994. We used a selfmade ELISA obtained from an
Detection of anti-HIV-1 IgG antibodies in whole saliva by GACELISA and Western blot assays.: East Afr Med J. 1996 May;73(5):292-4. Unique Identifier : AIDSLINE MED/96349661; Matee MI; Lyamuya EF; Simon E; Mbena EC; Kagoma C; Samaranayake LP; Scheutz F; Department of Microbiology and Immunology, Muhimbili University; College of Health Sciences, Dar es Salaam, Tanzania.; The present study, based on 158 HIV seropositives and 167 HIV seronegatives, demonstrates that saliva collected with the Omni-SAL device and tested with GACELISA (an IgG antibody capture ELISA) is an effective non-invasive alternative to serum for anti-HIV IgG antibody screening. The study also shows that a convention
AIDS-related knowledge and misconceptions among high secondary school teachers and students in Kassala, Sudan.: East Afr Med J. 1996 May;73(5):295-7. Unique Identifier : AIDSLINE MED/96349662; Elzubier AG; el Nour MH; Ansari EH; Department of Family and Community Medicine, College of Medicine; and Medical Sciences, King Faisal University, Dammam, Saudi; Arabia.; An AIDS-related knowledge study was carried out on a sample of 462 high secondary school teachers and students, in Kassala, eastern Sudan . The results showed high scores of knowledge about AIDS-transmission and general knowledge about the disease. However, there was a high frequency
Sentinel surveillance and cross sectional survey on HIV infection prevalence: a comparative study.: East Afr Med J. 1996 May;73(5):298-302. Unique Identifier : AIDSLINE MED/96349663; Kwesigabo G; Killewo JZ; Sandstrom A; Department of Epidemiology and Biostatistics, Muhimbili; University College of Health Sciences, Tanzania.; Despite widespread use of sentinel surveillance systems in monitoring the magnitude of HIV-1 infection in populations, little is known of how the trends they produce compare with those of the larger populations which they support to represent. The objective of this study, therefore, was to assess how useful sentinel s
Effect of HIV infection on the incidence of lymphoma in Africa.: East Afr Med J. 1996 May;73(5 Suppl):S29-30. Unique Identifier : AIDSLINE MED/96349684; Lucas SB; De Cock KM; Peacock C; Diomande M; Kadio A; Dept of Histopathology, UCL Medical School, London.
Pathology of paediatric human immunodeficiency virus infections in Cote d'Ivoi