1996

Reproductive hazards: an overview of exposures to health care workers.: AAOHN J. 1995 Dec;43(12):614-21. Unique Identifier : AIDSLINE MED/96327996; Shortridge-McCauley LA; 1. Anesthetic gases, particularly nitrous oxide, have been investigated for potential reproductive, mutagenic, and carcinogenic effects. Waste gases have been found in high concentrations, even with work settings with scavenger systems in place. 2. Antineoplastic drugs, commonly used to treat persons with cancer, are
Kaposi's sarcoma in children with AIDS in Europe and the United States [letter]: Eur J Cancer. 1996 Apr;32A(4):650-1. Unique Identifier : AIDSLINE MED/96273543; Serraino D; Franceschi S
PERC: a nursing syndrome for AIDS.: Nurs Diagn. 1996 Jan-Mar;7(1):19-23. Unique Identifier : AIDSLINE MED/96335567; Coler MS; Perc is an acronym and represents a proposed nursing syndrome for people with AIDS. It incorporates the NANDA human response patterns of perceiving, exchanging, relating and choosing. These patterns were identified through a review of literature on AIDS, especially that which addressed NANDA nursing diagnoses. The ana
Nursing diagnoses for hospitalized patients with AIDS.: Nurs Diagn. 1996 Jan-Mar;7(1):9-18. Unique Identifier : AIDSLINE MED/96335566; Smith AR; Chang BL; This study examined the reliability of nursing diagnoses identified from the medical records of 100 patients hospitalized for HIV disease on a 22-bed designated unit at a large metropolitan teaching hospital in Los Angeles. The diagnoses were identified in two ways: (a) staff nurses identified 16 different nursing dia
People are more likely to have unprotected sex after negative HIV tests, survey finds [news]: Nurs Stand. 1996 Jan 3-9;10(15):10. Unique Identifier : AIDSLINE MED/96329231
No limits. AIDS and community nursing [news]: Nurs Stand. 1996 Jan 3-9;10(15):49. Unique Identifier : AIDSLINE MED/96329243
No limits. Electives: mass appeal needed.: Nurs Stand. 1996 Jan 3-9;10(15):55. Unique Identifier : AIDSLINE MED/96329248; Jones C
Risk factors for occupational HIV [news]: Nurs Stand. 1996 Jan 31;10(19):28. Unique Identifier : AIDSLINE MED/96334542
Old diseases return [news]: Nurs Stand. 1996 Mar 20;10(26):12. Unique Identifier : AIDSLINE MED/96339893; Healy P
Giving advice on sex... and safety.: Nurs Stand. 1996 Apr 3;10(28):20. Unique Identifier : AIDSLINE MED/96339927; Woolf L; Topping-Morris B
AIDS epidemic [news]: Nurs Stand. 1996 Apr 3;10(28):29. Unique Identifier : AIDSLINE MED/96339932
[Current status of the management of cytomegalovirus retinitis in patients with AIDS (editorial)]: Enferm Infecc Microbiol Clin. 1996 Mar;14(3):137-41. Unique Identifier : AIDSLINE MED/96220635; Lopez-Cortes LF; Pachon-Diaz J
[Comparison of 2 ELFA methods for the automatized diagnosis of HIV infection]: Enferm Infecc Microbiol Clin. 1996 Mar;14(3):150-4. Unique Identifier : AIDSLINE MED/96220638; Ortiz de Lejarazu R; Eiros-Bouza JM; Martinez P; Reguera JI; Rodriguez-Torres A; Departamento de Microbiologia, Facultad de Medicina, Valladolid.; BACKGROUND: Evaluate two recent tests for HIV infection diagnosis using the Enzyme-Linked Fluorescent Assay (ELFA) technique for rapid diagnosis in microbiology or virology laboratories. METHODS: A panel of 429 sera with different Ab prevalencies and different sources was prepared: 50 blood bank samples from habitual
[Rhodococcus equi pneumonia in patients with HIV infection: report of 2 cases and review of the literature]: Enferm Infecc Microbiol Clin. 1996 Mar;14(3):177-80. Unique Identifier : AIDSLINE MED/96220643; Berna JD; Garcia-Medina V; Cano A; Guirao J; Lafuente A; Garcia-Orenes MC; Servicio de Radiologia, Hospital General Universitario de; Murcia.; BACKGROUND: Pneumonia by Rhodococcus equi is infrequent and is associated with patients with important immunosuppression. To date 66 cases of pneumonia by Rhodococcus equi in patients with HIV infection have been published. The diagnosis, problems in determining diagnosis and treatment are discussed. MATERIALS AND MET
[Fatal anaphylactic shock caused by rifampicin in a patient with HIV infection (letter)]: Enferm Infecc Microbiol Clin. 1996 Mar;14(3):200-1. Unique Identifier : AIDSLINE MED/96220651; Inmaculada Rubio M; Alvarez del Vayo C; Cisneros JM; Viciana P; Martinez-Marcos F
Squamous cell carcinomas of the anus and infection with human papillomavirus in patients with AIDS.: Eur J Surg. 1996 Mar;162(3):251-3. Unique Identifier : AIDSLINE MED/96265770; Munoz-Jimenez F; Louredo-Mendez AM; Turegano-Fuentes F; del Valle-Hernandez E; Lacruz-Pelea C; Department of General Surgery, General University Hospital,; Gregorio Maranon, Madrid, Spain.
AIDS programmes at the workplace: a scoresheet for assessing the quality of services.: Occup Med (Oxf). 1996 Jun;46(3):216-20. Unique Identifier : AIDSLINE MED/96312064; London L; Department of Community Health, University of Cape Town,; Observatory, South Africa.; Little data is available on the extent or comprehensiveness of AIDS prevention activities at South African workplaces. A cross-sectional postal survey was performed of all members of the local occupational health nursing association in the area of greater Cape Town in 1994 to assess the quality of such programmes. Use
Human immunodeficiency virus (HIV) phenotype and interleukin-2/ interleukin-10 ratio are associated markers of protection and progression in HIV infection.: Blood. 1996 Jul 15;88(2):574-9. Unique Identifier : AIDSLINE MED/96289506; Clerici M; Balotta C; Salvaggio A; Riva C; Trabattoni D; Papagno L; Berlusconi A; Rusconi S; Villa ML; Moroni M; Galli M; Cattedra di Immunologia, Universita degli Studi di Milano,; Padiglione L.I.T.A., Ospedale Luigi Sacco, Italy.; Human immunodeficiency virus (HIV) isolability, rate of viral replication, HIV phenotype, type 1 and type 2 cytokine production, and CD4 counts were cross sectionally analyzed in 63 HIV seropositive (HIV+) individuals to establish possible correlations between virologic and immunologic markers of protection and progre
Apoptosis of Burkitt's lymphoma cells induced by specific interaction of surface IgM with a self-antigen: implications for lymphomagenesis in acquired immunodeficiency syndrome.: Blood. 1996 Jul 15;88(2):599-608. Unique Identifier : AIDSLINE MED/96289509; Roncella S; Cutrona G; Favre A; Ulivi M; Fais F; Signorini A; Grossi CE; Chiorazzi N; Ferrarini M; Servizi di Immunologia Clinica e Patologia Clinica, Istituto; Nazionale per la Ricerca sul Cancro-IST, Genova, Italy.; In a previous study, we described a cell line (BRG-P) derived from a woman with Burkitt s lymphoma (BL) and acquired immunodeficiency syndrome that shared the same characteristic cytogenetic abnormalities as the patient s malignant cells. This cell line contained subclones that displayed an isotype switch from IgM to
Primary effusion lymphoma: a distinct clinicopathologic entity associated with the Kaposi's sarcoma-associated herpes virus.: Blood. 1996 Jul 15;88(2):645-56. Unique Identifier : AIDSLINE MED/96289513; Nador RG; Cesarman E; Chadburn A; Dawson DB; Ansari MQ; Sald J; Knowles DM; Department of Pathology, New York Hospital-Cornell Medical; Center, New York 10021, USA.; We recently discovered the Kaposi s sarcoma-associated herpes virus (KSHV/HHV-8) in an uncommon and unusual subset of AIDS-related lymphomas that grow mainly in the body cavities as lymphomatous effusions without an identifiable contiguous tumor mass. The consistent presence of KSHV and certain other distinctive featu
Generation of primary antigen-specific human cytotoxic T lymphocytes in human/mouse radiation chimera.: Blood. 1996 Jul 15;88(2):721-30. Unique Identifier : AIDSLINE MED/96289522; Segall H; Lubin I; Marcus H; Canaan A; Reisner Y; Department of Membrane Research and Biophysics, Weizmann; Institute of Science, Rehovot, Israel.; Severe combined immunodeficient (SCID) mice are increasingly used as hosts for the adoptive transfer of human lymphocytes. Human antibody responses can be obtained in these xenogeneic chimeras, but information about the functionality of the human T cells in SCID mice is limited and controversial. Studies using human p
Recombinant human macrophage colony-stimulating factor in nonhuman primates: selective expansion of a CD16+ monocyte subset with phenotypic similarity to primate natural killer cells.: Blood. 1996 Aug 15;88(4):1215-24. Unique Identifier : AIDSLINE MED/96329554; Munn DH; Bree AG; Beall AC; Kaviani MD; Sabio H; Schaub RG; Alpaugh RK; Weiner LM; Goldman SJ; Division of Pediatric Hematology-Oncology, Medical College of; Georgia, Augusta, USA.; The CD16 receptor (Fc gamma R-III) is found on many tissue macrophages (M phi s), but its expression on circulating monocytes is restricted to a small, phenotypically distinct subset. The number of these CD16+ monocytes may be markedly increased in response to sepsis, human immunodeficiency virus infection, or metasta
Sezary syndrome T-cell clones display T-helper 2 cytokines and express the accessory factor-1 (interferon-gamma receptor beta-chain).: Blood. 1996 Aug 15;88(4):1383-9. Unique Identifier : AIDSLINE MED/96329572; Dummer R; Heald PW; Nestle FO; Ludwig E; Laine E; Hemmi S; Burg G; Department of Dermatology, University of Zurich Medical School,; Switzerland.; Sezary syndrome (SS) is a leukemic variant of low-grade cutaneous T-cell lymphomas (CTCLs). The clonal T cells in this lymphoproliferative disorder are poorly characterized. Using antibodies against the variable region of the T-cell receptor (TCR V alpha/beta), we identified four predominant T-cell clones (two V beta
A clonally distinct recurrence of Burkitt's lymphoma at 15 years.: Blood. 1996 Aug 15;88(4):1407-10. Unique Identifier : AIDSLINE MED/96329575; Lister J; Miklos JA; Swerdlow SH; Bahler DW; Department of Medicine, University of Pittsburgh School of; Medicine, PA 15213-2582, USA.; A human immunodeficiency virus-negative male was successfully treated for two occurrences of Burkitt s lymphoma, 15 years apart. As consolidation of his second remission, he underwent high-dose chemotherapy with peripheral blood stem cell transplantation. In an effort to prove whether the second lymphoma was a relapse
Boromycin, an anti-HIV antibiotic.: Biosci Biotechnol Biochem. 1996 Jun;60(6):1036-7. Unique Identifier : AIDSLINE MED/96294286; Kohno J; Kawahata T; Otake T; Morimoto M; Mori H; Ueba N; Nishio M; Kinumaki A; Komatsubara S; Kawashima K; Lead Generation Research Laboratory at Toda, Tanabe Seiyaku Co.,; Ltd., Saitama, Japan.; The polyether-macrolide antibiotic, boromycin, was isolated as a potent anti-human immunodeficiency virus (HIV) antibiotic from a fermentation broth of Streptomyces sp. A-3376. Boromycin was found to strongly inhibit the replication of the clinically isolated HIV-1 strain as well as the cultured strain in in vitro lab
Prevention of HIV infection [letter]: Acta Paediatr. 1996 Mar;85(3):280. Unique Identifier : AIDSLINE MED/96282748; Etzioni A; Pollack S; Ben-Ishai Z
Talking with elementary school-age children about AIDS and death: principles and guidelines for school nurses.: J Sch Nurs. 1996 Feb;12(1):26-32. Unique Identifier : AIDSLINE MED/96335332; Schonfeld DJ; Teaching school children about sensitive or controversial issues presents difficulties for classroom teachers as well as school nurses. At each developmental stage, there is appropriate information that can be absorbed by children that will help them in dealing with such things as death and AIDS. However, many childre
Research, language, politics, complacency and AIDS [editorial]: Contemp Nurse. 1995 Sep;4(3):94-6. Unique Identifier : AIDSLINE MED/96325780; Kerr PG
Changing attitudes.: Contemp Nurse. 1995 Dec;4(4):178-9. Unique Identifier : AIDSLINE MED/96325797; Crock E; Kleeman M
Network between main protagonists and events leading to AIDS.: Arch Med Res. 1996 Summer;27(2):107-13. Unique Identifier : AIDSLINE MED/96276731; Larralde C; Huerta L; Departamento de Immunologia, Universidad Nacional Autonoma de; Mexico, Mexico, D.F.; A definitive single hypothesis about HIV pathogenesis is still lacking in specialized literature. Rather, a picture of the extreme complexity in AIDS causality ensues from the extensive information available. This article contains an outline of the most relevant data on the subject of AIDS pathogenesis, organized into
The spectrum of HIV infection in patients seen at a private hospital in Mexico City: 115 patients seen from 1984 to 1990.: Arch Med Res. 1996 Summer;27(2):201-4. Unique Identifier : AIDSLINE MED/96276746; del Rio-Chiriboga C; Tellez-Gomez I; Orzechowski-Rallo A; Alanis-Ortega A; Section of Internal Medicine and Infectious Diseases, Hospital; Angeles del Pedregal, Mexico, D.F.; The objective of this study was to describe the epidemiology and clinical presentation of HIV infection among upper middle class patients in Mexico City. A retrospective review of outpatient and hospital records of all HIV-infected patients was accomplished by one of the authors between 1984 and 1990. A total of 115 p
Common problems with wound care: infection with HIV.: Br J Nurs. 1995 Nov 9-22;4(20):1219-23. Unique Identifier : AIDSLINE MED/96332056; Kiernan M; Young T; The issue of the care required by wounded patients infected with human immunodeficiency virus should be addressed by all nursing personnel. The virus can be transmitted through blood, blood products or wound exudate. Promotion of universal precautions should greatly minimise the risk. The patient s infection status is
Disseminated Penicillium marneffei infection in a patient with acquired immunodeficiency syndrome.: J Formos Med Assoc. 1995 Sep;94(9):572-5. Unique Identifier : AIDSLINE MED/96241083; Chang CC; Liao ST; Huang WS; Liu JD; Shih LS; Department of Internal Medicine, Taipei Municipal Jen-Ai; Hospital, Taiwan.; Penicillium marneffei is a rare human pathogen in Southeast Asia and Southern China . A 26-year-old heterosexual male had intermittent fever, diarrhea and weight loss for 3 months. He was severely immune deficient (CD4+ count, 4/microL) and serologic tests for antibodies against huma
Culture, drugs and unsafe sex: confusion about causation [editorial]: Addiction. 1996 Jun;91(6):753-8. Unique Identifier : AIDSLINE MED/96276705; Rhodes T
Ethics in nursing practice: confidentiality for women and their children with HIV/AIDS.: Medsurg Nurs. 1995 Dec;4(6):452-7. Unique Identifier : AIDSLINE MED/96335500; Pinch WJ; Dougherty CJ; McCarthy V; HIV-positive women and their children experience substantial problems brought about by the illness itself and service-delivery issues. Significant ethical concerns are raised when providing care to this patient population, and the ramifications of compromises in patient confidentiality are extremely serious. All pract
Reducing risks in blood transfusion: process and outcome.: Transfus Med. 1996 Mar;6(1):1-10. Unique Identifier : AIDSLINE MED/96265656; McClelland DB; McMenamin JJ; Moores HM; Barbara JA; Edinburgh South East Scotland Blood Transfusion Service, UK.; The last decade has seen substantial improvements in the provision of safe infection-free blood for patients in many countries. This has resulted from the combined effects of better donor education, selection, testing and exclusion processes. The residual risk of infection with HBsAg attributable to laboratory error
Behavioural risk factors for HIV infection amongst blood donors in London.: Transfus Med. 1996 Mar;6(1):31-6. Unique Identifier : AIDSLINE MED/96265659; Cowan FM; Johnson AM; Wadsworth J; Brennan M; Academic Department of Genitourinary Medicine, University College; London Medical School, UK.; This paper compares the prevalence of risk factors for sexual acquisition of human immunodeficiency virus infection (HIV-1) among blood donors with the risk in the general population. Sexual behaviour data collected as part of a cross-sectional survey of central London blood donors were compared, after indirect standa
High-performance liquid chromatographic separation of an HIV-1 reverse transcriptase inhibitor and its enantiomer.: J Chromatogr A. 1996 Jul 12;738(2):290-4. Unique Identifier : AIDSLINE MED/96314844; Wang T; Grinberg N; Bicker G; Tway P; Thompson K; Analytical Research Department, Merck Research Laboratories,; Rahway, NJ 07065-0900, USA.; This article describes the direct separation of an HIV-1 reverse transcriptase inhibitor and its enantiomer by HPLC on a silica-bonded polyacrylamide (ChiraSpher) column. The column selection was based on specific interactions between the individual enantiomers and the chiral stationary phase. The influence of some ch
[Indemnity payment: secret HIV test is the basis for claim]: Pflege Z. 1996 Jan;49(1):34-6. Unique Identifier : AIDSLINE MED/96327520; Grosskopf V
[Hospital pneumonia due to Xanthomonas maltophilia and AIDS (letter)]: Arch Bronconeumol. 1996 May;32(5):259-60. Unique Identifier : AIDSLINE MED/96265699; Sitges M; Mito O; Pedrol E
Severe complications of perianal sepsis in patients with human immunodeficiency virus.: Br J Surg. 1996 Jun;83(6):778-80. Unique Identifier : AIDSLINE MED/96334831; Consten EC; Slors JF; Danner SA; Sars PR; Obertop H; Van Lanschot JJ; Department of Surgery, Academic Medical Centre, Amsterdam, The; Netherlands.; Fifty human immunodeficiency virus (HIV)-infected patients with perianal sepsis were studied. Seven (14 per cent) had serious septic complications, four patients with severe necrotizing gangrene, and three with abscesses in the mediastinum, liver and brain respectively. CD4+ lymphocyte counts were significantly lower
Importance of human immunodeficiency virus-associated lymphadenopathy and tuberculous lymphadenitis in patients undergoing lymph node biopsy in Zambia [letter]: Br J Surg. 1996 Jun;83(6):869. Unique Identifier : AIDSLINE MED/96334858; Sarela A
Retroviral integrases and their cousins.: Curr Opin Struct Biol. 1996 Feb;6(1):76-83. Unique Identifier : AIDSLINE MED/96284114; Rice P; Craigie R; Davies DR; Laboratory of Molecular Biology,National Institute of Diabetes; and Digestive and Kidney Diseases, National Institutes of Health,; Bethesda, MD 20892-0540, USA.; The recently determined structures of the catalytic domains of HIV integrase, avian sarcoma virus integrase and the Mu transposase are strikingly similar to each other and also exhibit significant similarity to several nucleases. All these enzymes of cut polynucleotides, leaving 3 OH and 5 PO4 groups. The integrase an
Mother-to-infant transmission of hepatitis C virus in human immunodeficiency virus-coinfected mother: a case report.: J Obstet Gynaecol Res. 1996 Apr;22(2):139-42. Unique Identifier : AIDSLINE MED/96280289; Koseki S; Taga M; Aoyama M; Hirabuki T; Hirahara F; Takahasi T; Minaguchi H; Yokota S; Ito A; Department of Obstetrics and Gynecology, Yokohama City University; School of Medicine, Japan.; We report a case of vertical transmission of HCV in a mother infected with both HCV and HIV. Our case suggests that coinfection with HIV, by causing an immune dysfunction, might be one of the risk factors for the transmission of HCV.
Gastric lesions in 76 patients with adult T-cell leukemia/lymphoma. Endoscopic evaluation.: Cancer. 1996 Aug 1;78(3):396-402. Unique Identifier : AIDSLINE MED/96320566; Sakata H; Fujimoto K; Iwakiri R; Mizuguchi M; Koyama T; Sakai T; Inoue E; Tokunaga O; Shimamoto Y; Division of Gastroenterology, Department of Internal Medicine,; Saga Medical School, Saga, Japan.; BACKGROUND: Adult T-cell leukemia/lymphoma (ATLL) is caused by human T-lymphotropic virus type I. Gastric lesions in ATLL have not been described precisely, whereas the clinical features of ATLL have been well documented. The goal of the present study was to review gastric lesions, including gastric involvement, of pa
Low dose methotrexate, bleomycin, doxorubicin, cyclophosphamide, vincristine, and dexamethasone with zalcitabine in patients with acquired immunodeficiency syndrome-related lymphoma. Effect on human immunodeficiency virus and serum interleukin-6 levels over time.: Cancer. 1996 Aug 1;78(3):517-26. Unique Identifier : AIDSLINE MED/96320583; Levine AM; Tulpule A; Espina B; Boswell W; Buckley J; Rasheed S; Stain S; Parker J; Nathwani B; Gill PS; Department of Medicine, Division of Hematology, University of; Southern California School of Medicine, Los Angeles, USA.; BACKGROUND: Use of multiagent chemotherapy has been associated with complete remission (CR) in approximately 50% of patients with newly diagnosed acquired immunodeficiency syndrome (AIDS)-lymphoma, although additional AIDS-related complications may occur. Both chemotherapy and antiretroviral therapy were employed in a
The effects of 5-fluorouracil and doxorubicin on expression of human immunodeficiency virus type 1 long terminal repeat.: Cancer Lett. 1996 Aug 2;105(2):217-23. Unique Identifier : AIDSLINE MED/96319712; Panozzo J; Akan E; Griffiths TD; Woloschak GE; Center for Mechanistic Biology and Biotechnology, Argonne; National Laboratory, IL 60439-4833, USA.; Previous work by many groups has documented induction of the human immunodeficiency virus (HIV) long terminal repeat (LTR) following exposure of cells to ultraviolet light and other DNA damaging agents. Our experiments set out to determine the relative activation or repression of the HIV-LTR in response to two classes
Planned and unplanned postoperative admissions to critical care for mechanical ventilation [see comments]: Can J Anaesth. 1996 Apr;43(4):333-40. Unique Identifier : AIDSLINE MED/96282191; Rose DK; Byrick RJ; Cohen MM; Caskennette GM; Department of Anaesthesia, St. Michael's Hospital, Toronto,; Ontario.; PURPOSE: To determine which factors influence the clinician in choosing critical care admission and postoperative ventilation, we prospectively examined the incidence, timing, causes, and risk factors for admission to critical care for postoperative ventilation within 48 hr of a surgical procedure (excluding cardiac a
Peptide immunization in humans: a combined CD8+/CD4+ T cell-targeted vaccine restimulates the memory CD4 T cell response but fails to induce cytotoxic T lymphocytes (CTL).: Clin Exp Immunol. 1996 Jul;105(1):18-25. Unique Identifier : AIDSLINE MED/96280772; Brander C; Corradin G; Hasler T; Pichler WJ; Institute of Immunology and Allergology, Inselspital, Bern,; Switzerland.; Immunization with short antigenic peptides represents a potential strategy to induce peptide-specific CTL in vivo. In this study, a synthetic vaccine consisting of an HIV-derived, HLA-A2.1-binding CTL epitope and a tetanus toxin-derived T helper epitope was evaluated for its capacity to induce peptide-specific CTL in
Selective CD4+ T cell deletion after specific activation in HIV-infected individuals; protection by anti-CD28 monoclonal antibodies.: Clin Exp Immunol. 1996 Jul;105(1):31-8. Unique Identifier : AIDSLINE MED/96280774; Cottrez F; Capron A; Groux H; Unite INSERM U167, Institut Pasteur, Lille, France.; AIDS is characterized by a progressive decline in the number of CD4+ T cells. This is preceded by an early selective defect in the proliferation of these cells to recall antigens [1-3], pokeweed mitogen (PWM) [4-6] and to superantigens (SAg) [4,7]. In contrast, the proliferative response to phytohaemagglutinin (PHA) r
Complement-dependent cytotoxic antibodies to human T lymphotropic virus type I (HTLV-I)-infected cells in the sera of HTLV-I-infected individuals.: Clin Exp Immunol. 1996 Jul;105(1):39-45. Unique Identifier : AIDSLINE MED/96280775; Plotnicky-Gilquin H; Afani A; Vernant JC; Desgranges C; Unite de Recherche sur les Hepatites, INSERM U271, Lyon,; France.; To investigate whether HTLV-I induces the development of complement-dependent cytotoxic antibodies in humans, sera of asymptomatic HTLV-I carriers and of patients suffering from tropical spastic paraparesis/HTLV-I-associated myelopathy (TSP/HAM) or adult T cell leukaemia (ATL) were used in a cytotoxicity assay against
Rapidly progressive seronegative spondylarthropathy with atlantodental subluxation in a patient with moderately advanced HIV infection.: Clin Exp Rheumatol. 1996 Jan-Feb;14(1):83-5. Unique Identifier : AIDSLINE MED/96259626; Schewe CK; Kellner H; Medizinische Poliklinik, Klinikum Innenstadt, Universitat; Munchen, Germany.; It has been suggested that the immunosuppressed state associated with HIV infection may influence the clinical course of rheumatic diseases. We describe the case of a patient with moderately advanced HIV infection who developed a psoriatic rash and a rapidly progressive spondylarthropathy of the cervical spine with at
A decade of research on the natural history of HIV infection: Part 1. Markers.: Clin Invest Med. 1996 Apr;19(2):111-20. Unique Identifier : AIDSLINE MED/96260549; Strathdee SA; O'Shaughnessy MV; Montaner JS; Schechter MT; British Columbia Centre for Excellence in HIV/AIDS.; Within the context of HIV disease, a marker may be described as a consequence of disease that varies over time but does not necessarily predict future disease course. To date, the most powerful marker of HIV disease progression is the CD4 cell count. Other immunologic markers include neopterin, beta 2-microglobulin, a
A decade of research on the natural history of HIV infection: Part 2. Cofactors.: Clin Invest Med. 1996 Apr;19(2):121-30. Unique Identifier : AIDSLINE MED/96260550; Strathdee SA; Hogg RS; O'Shaughnessy MV; Montaner JS; Schechter MT; British Columbia Centre for Excellence in HIV/AIDS.; Cofactors of HIV disease may be considered risk modifiers that are causally related to future disease course. The search for potential cofactors, of viral, host or environmental origin, may provide avenues for altering the natural history of HIV infection. Potential viral cofactors include viral strains, such as syncy
Radiologic and laboratory evaluation of enhancing brain lesions in patients with AIDS.: Compr Ther. 1995 Nov;21(11):645-52. Unique Identifier : AIDSLINE MED/96238321; Johnson MD; Creasy JL; Department of Pathology, Vanderbilt University School of; Medicine, Nashville, TN 37232-2561, USA.
Chlamydia pneumoniae pneumonia in hospitalized patients. Clinical characteristics and diagnostic value of polymerase chain reaction detection in BAL.: Chest. 1996 Aug;110(2):351-6. Unique Identifier : AIDSLINE MED/96325993; Dalhoff K; Maass M; Department of Internal Medicine II, Medical University of; Luebeck, Germany.; STUDY OBJECTIVE: To evaluate the incidence and clinical characteristics of Chlamydia pneumoniae infection as detected by polymerase chain reaction (PCR) and culture of BAL in hospitalized patients with pneumonia, HIV-infected persons, and control subjects. DESIGN: Prospective, comparative clinical study. SETTING: Univ
Kaposi's sarcoma of the tip of the nose as a sentinel sign for Kaposi's sarcoma of the lung [letter]: Chest. 1996 Aug;110(2):576. Unique Identifier : AIDSLINE MED/96326035; Masih RB; Jesudass SW; Verghese A
[Effects of thymectomy and glucocorticoid therapy on peripheral lymphocytes in myasthenia gravis]: Chung Hua Nei Ko Tsa Chih. 1995 Aug;34(8):514-7. Unique Identifier : AIDSLINE MED/96329747; Huang Y; Xu X; Lin J; Peking Union Medical College Hospital, Beijing.; Clinical manifestations and peripheral blood lymphocyte subset changes were studied in patients with myasthenia gravis (MG) to elucidate the mechanism of clinical improvement following treatment, with thymectomy (Tx) or glucocorticoid (GC) therapy. The changes found were: 1. There was a significant increase in percent
[Expression of adhesion molecules on lymphocyte in patients with systemic lupus erythematosus]: Chung Hua Nei Ko Tsa Chih. 1995 Aug;34(8):545-7. Unique Identifier : AIDSLINE MED/96329755; Zhou T; Jiang Y; Yao J; Ruijin Hospital, Shanghai Second Medical University.; Peripheral blood lymphocyte phenotype (CD3, CD4, CD8, CD20, CD45RA and CD45RO) and adhesion molecule phenotype (CD11a/LFA-1 alpha, CD18/LFA-1 beta and CD54/ICAM-1) were investigated in 35 patients with systemic lupus erythematosus (SLE) by using flow cytometric analysis and dual immunofluorescence staining method. Res
Individual and situational markers of condom use and sex with nonprimary partners among alcoholic inpatients: findings from the ATRISK Study.: Health Psychol. 1996 May;15(3):185-92. Unique Identifier : AIDSLINE MED/96336123; Scheidt DM; Windle M; Research Institute on Addictions, Buffalo, New York, USA.; dscheidt@acspr1.acs.brockport.edu; Alcoholics in treatment have demonstrated increased rates of HIV risk behavior and infection. This study explored individual and situational variables associated with HIV risk behaviors such as condom nonuse and sex with nonprimary partners reported during structured interviews of 802 male and female alcoholic inpatie
Applications of the monitoring process model to coping with severe long-term medical threats.: Health Psychol. 1996 May;15(3):216-25. Unique Identifier : AIDSLINE MED/96336127; Miller SM; Rodoletz M; Mangan CE; Schroeder CM; Sedlacek TV; Division of Population Science, Fox Chase Cancer Center,; Philadelphia, Pennsylvania 19107, USA. sm.miller@fccc.edu; Guided by the monitoring process model (MPM), the authors explored the illness responses of 2 samples: high monitors (who are cognitively vigilant to and amplify threat-related cues) and low monitors (who avoid them and blunt their impact). Both samples-101 women with human papillomavirus-related precancerous cervical
The solution structure of the bovine leukaemia virus matrix protein and similarity with lentiviral matrix proteins.: EMBO J. 1996 Jul 1;15(13):3267-74. Unique Identifier : AIDSLINE PDB; Matthews S; Mikhailov M; Burny A; Roy P; Department of Biochemistry, Imperial College of Science,; Technology and Medicine, University of London, UK.; sjm@bioch.ox.ac.uk; In the mature virion, retroviral matrix proteins are found in association with the inner face of the viral membrane. They play a critical role in determining the morphogenesis of virus assembly. We have determined the three-dimensional solution structure of the bovine leukaemia virus (BLV) matrix protein by heteronucl
Identification of AIDS-related tuberculosis with concordant gallium-67 and three-hour delayed thallium-201 scintigraphy.: Eur J Nucl Med. 1996 Jul;23(7):852-4. Unique Identifier : AIDSLINE MED/96269981; Gomez MV; Gallardo FG; Cobo J; Babe J; Servicio de Medicina Nuclear, Instituto de Salud Carlos III,; Madrid, Spain.; Concordant gallium-67 and thallium-201 uptake has been described in malignant lesions. More recently, 201Tl accumulation has been described in some benign conditions. The authors report three HIV-positive patients who underwent 67Ga and 201Tl scintigraphy. These studies revealed concordant 67Ga and 201Tl uptake and tu
Chronic unexplained diarrhea in human immunodeficiency virus infection: determination of the best diagnostic approach [letter]: Gastroenterology. 1996 Jul;111(1):269-71. Unique Identifier : AIDSLINE MED/96315578; Simon D; Kotler DP; Brandt LJ
[Comparative study of the placenta from HIV+ mothers. Ultrastructural analysis]: Ginecol Obstet Mex. 1996 Apr;64:167-76. Unique Identifier : AIDSLINE MED/96233329; Villegas-Castrejon H; Paredes-Vivas Y; Flores-Rivera E; Gorbea-Robles MC; Arredondo-Garcia JL; Instituto Nacional de Perinatologia, Mexico, D.F.; Perinatal vertical transmission has increased in all the world; it is considered that at the present time there are about one million of children with HIV. Variation goes from 12 to 40%, at different countries. During the last years antiretroviral drugs as
Meeting the social service needs of persons with AIDS: hospices' response.: Hosp J. 1995;10(4):49-65. Unique Identifier : AIDSLINE MED/96329978; Kovacs PJ; Rodgers AY; A national sample of 148 directors of hospice social service departments (or persons most familiar with the delivery of social services in the hospice) participated in an exploratory study investigating the effects of the acquired immune deficiency syndrome (AIDS) epidemic on the delivery of hospice social services. F
Neuropathology of human immunodeficiency virus: questions and answers [editorial]: Hum Pathol. 1996 Jul;27(7):623-4. Unique Identifier : AIDSLINE MED/96320623; Petito CK
Neuropathology of human immunodeficiency virus infection at different disease stages.: Hum Pathol. 1996 Jul;27(7):637-42. Unique Identifier : AIDSLINE MED/96320626; Kibayashi K; Mastri AR; Hirsch CS; Office of Chief Medical Examiner of the City of New York, NY; 10016-6402, USA.; The authors studied the brains of 471 adults infected with human immunodeficiency virus type 1 (HIV-1): 123 asymptomatic carriers, 127 in an early stage of acquired immunodeficiency syndrome (AIDS) with pulmonary tuberculosis or bacterial infections, and 221 in fully developed AIDS with opportunistic infections or neo
Distribution of transforming growth factor-beta isoforms in human immunodeficiency virus-1 encephalitis.: Hum Pathol. 1996 Jul;27(7):643-9. Unique Identifier : AIDSLINE MED/96320627; Johnson MD; Gold LI; Department of Pathology, Vanderbilt Medical School, Nashville, TN; 37232, USA.; The transforming growth factor-beta family of polypeptides includes three related isoforms with pervasive effects on immune system function. In this study, the authors evaluated human brains with human immunodeficiency virus (HIV)-1 encephalitis for transforming growth factor beta (TGFbeta)1, TGFbeta2, and TGFbeta3 im
Crusted (Norwegian) scabies in a specialist HIV unit: successful use of ivermectin and failure to prevent nosocomial transmission.: Genitourin Med. 1996 Apr;72(2):115-7. Unique Identifier : AIDSLINE MED/96273399; Corbett EL; Crossley I; Holton J; Levell N; Miller R; De Cock KM; HIV/AIDS Unit Camden & Islington Community Health Services NHS; Trust, Middlesex Hospital, London, UK.; A nosocomial outbreak of scabies in a specialist inpatient HIV unit resulted from a patient admitted with crusted scabies. Treatment of his infestation with topical scabicides alone failed and he remained infectious for several weeks. His infestation was then eradicated with combined topical treatment and oral ivermec
Hepatitis C virus infection in a large cohort of homosexually active men: independent associations with HIV-1 infection and injecting drug use but not sexual behaviour.: Genitourin Med. 1996 Apr;72(2):118-22. Unique Identifier : AIDSLINE MED/96273400; Bodsworth NJ; Cunningham P; Kaldor J; Donovan B; Taylor Square Private Clinic, Darlinghurst, New South Wales,; Australia.; OBJECTIVE: To determine the prevalence and risk factors for hepatitis C virus (HCV) infection in a cohort of homosexually active men, with particular reference to assessing sexual transmission. DESIGN: Prevalence based on cross-sectional testing for HCV (c100 protein) antibody in a cohort using sera stored between 198
Changes in heterosexual university undergraduates' HIV-related knowledge, attitudes and behaviour: Melbourne, 1989-1994.: Genitourin Med. 1996 Apr;72(2):123-7. Unique Identifier : AIDSLINE MED/96273401; Rosenthal DA; Smith AM; Reichler H; Moore S; Centre for the Study of Sexually Transmissible Diseases, LaTrobe; University, Carlton South, Australia.; OBJECTIVE: To examine differences in the AIDS-related knowledge, attitudes and behaviours of first year university undergraduates in 1989 and 1994. DESIGN: Comparisons were made between cross-sectional surveys, conducted in 1989 and 1994, of first year undergraduates at three Melbourne universities. RESULTS: The 1994
Epidemiology of cryptosporidiosis among European AIDS patients.: Genitourin Med. 1996 Apr;72(2):128-31. Unique Identifier : AIDSLINE MED/96273402; Pedersen C; Danner S; Lazzarin A; Glauser MP; Weber R; Katlama C; Barton SE; Lundgren JD; Department of Infectious Diseases, Hvidovre Hospital, Denmark.; OBJECTIVE: To study epidemiology and possible risk factors associated with the development of cryptosporidiosis among European patients with AIDS. METHODS: An inception cohort of 6548 patients with AIDS, consecutively diagnosed from 1979 to 1989, from 52 centres in 17 European countries was studied. Data on all AIDS d
Disseminated Toxoplasma gondii infection presenting with a fulminant pneumonia [clinical conference]: Genitourin Med. 1996 Apr;72(2):139-43. Unique Identifier : AIDSLINE MED/96273406; Miller RF; Lucas SB; Bateman NT; Department of Academic Genitourinary Medicine, University College; London Medical School, UK.
Should screening of genital infections be part of antenatal care in areas of high HIV prevalence? [letter]: Genitourin Med. 1996 Apr;72(2):148. Unique Identifier : AIDSLINE MED/96273412; L'Herminez M; L'Herminez R; Holtby I
Syndromic management of genital ulcer disease--a critical appraisal [letter]: Genitourin Med. 1996 Apr;72(2):148. Unique Identifier : AIDSLINE MED/96273411; Bhargava R; Mathur D; Bhargava P
Sexually transmitted diseases control in developing countries.: Genitourin Med. 1996 Apr;72(2):83-8. Unique Identifier : AIDSLINE MED/96273392; Adler MW; Academic Department of Genitourinary Medicine, Mortimer Market; Centre, London, UK.; Sexually transmitted diseases (STDs) are a major public health problem now compounded by the advent of AIDS and HIV infection. The size of the problem represented by STDs and HIV is unknown however it is estimated that there are 333 million new cases of STD per annum and currently 15-20 million people infected worldwi
Prevention and management of tuberculosis in HIV positive patients living in countries with a low prevalence of Mycobacterium tuberculosis.: Genitourin Med. 1996 Apr;72(2):89-92. Unique Identifier : AIDSLINE MED/96273393; Brook MG; Miller RF; Department of Medicine, Camden & Islington Community Health; Services NHS Trust, London, UK.; We have re-examined the evidence on which current British Thoracic Society recommendations for primary and secondary prophylaxis and therapy of tuberculosis are based. We suggest that in a country such as the UK with a low prevalence of tuberculosis, primary prophylaxis should be offered primarily to tuberculin positi
Induction of single and dual cytotoxic T-lymphocyte responses to viral proteins in mice using recombinant hybrid Ty-virus-like particles.: Immunology. 1996 Feb;87(2):171-8. Unique Identifier : AIDSLINE MED/96245967; Layton GT; Harris SJ; Myhan J; West D; Gotch F; Hill-Perkins M; Cole JS; Meyers N; Woodrow S; French TJ; Adams SE; Kingsman AJ; British Biotech Pharmaceuticals Ltd, Oxford, UK.; The induction of cytotoxic T-lymphocyte (CTL) responses to viral proteins is thought to be an essential component of protective immunity against viral infections. Methods for generating such responses in a reproducible manner would be of great value in vaccine development. We demonstrate here that the recombinant anti
Expression of L-selectin (CD62L) discriminates Th1- and Th2-like cytokine-producing memory CD4+ T cells.: Immunology. 1996 Feb;87(2):186-90. Unique Identifier : AIDSLINE MED/96245969; Kanegane H; Kasahara Y; Niida Y; Yachie A; Sughii S; Takatsu K; Taniguchi N; Miyawaki T; Department of Pediatrics, School of Medicine, Kanazawa; University, Japan.; Human memory (CD45RO+) CD4+ T cells can be distinguished into two subpopulations on the basis of expression of the lymph node homing receptor, L-selectin (CD62L). In a prior study we showed that human L-selectin-positive memory T-helper (Th) cells promote the maturation of IgG- and IgA-producing cells by naive B cells
T-cell-receptor dose and the time of treatment during murine retrovirus infection for maintenance of immune function.: Immunology. 1996 Feb;87(2):198-204. Unique Identifier : AIDSLINE MED/96245971; Liang B; Ardestani S; Marchalonis JJ; Watson RR; Department of Family and Community Medicine, University of; Arizona, Tucson 85724, USA.; C57BL/6 mice were injected with different doses of human T-cell receptor (TCR) V beta 8.1 CDR1 peptide at different times after murine retrovirus (LP-BM5) infection. Injection with TCR V beta 8.1 CDR1 peptide largely prevented the retrovirus-induced reduction in B- and T-cell proliferation, and T-helper 1 (Th1) cytoki
CD8-deficient mice exhibit augmented mucosal immune responses and intact adjuvant effects to cholera toxin.: Immunology. 1996 Feb;87(2):220-9. Unique Identifier : AIDSLINE MED/96245974; Hornquist E; Grdic D; Mak T; Lycke N; Department of Medical Microbiology and Immunology, University of; Goteborg, Sweden.; We used normal, CD4 and CD8 gene-targeted mice to investigate the role of CD4+ and CD8+ T cells in the regulation of gut mucosal immune responses following oral immunizations with cholera toxin (CT) adjuvant. Phenotypic analysis of mucosa-associated tissues revealed normal CD3+ T-cell frequencies in CD4-/- and CD8-/-
Dynamic changes in circulating and antigen-responsive T-cell subpopulations post-Mycobacterium bovis infection in cattle.: Immunology. 1996 Feb;87(2):236-41. Unique Identifier : AIDSLINE MED/96245976; Pollock JM; Pollock DA; Campbell DG; Girvin RM; Crockard AD; Neill SD; Mackie DP; Veterinary Sciences Division, Department of Agriculture for; Northern Ireland, Stormont, Belfast.; Bovine tuberculosis is a threat to animal and human health in several countries. Greater understanding of the immunology of the disease is required to develop improved tests and vaccines. This study has used a model of bovine tuberculosis, established in the natural host, to investigate the dynamic changes that occur
Impaired immunity and altered pulmonary responses in mice with a disrupted interferon-gamma receptor gene exposed to the irradiated Schistosoma mansoni vaccine.: Immunology. 1996 Feb;87(2):275-82. Unique Identifier : AIDSLINE MED/96245982; Wilson RA; Coulson PS; Betts C; Dowling MA; Smythies LE; Department of Biology, University of York, UK.; A high level of protection against Schistosoma mansoni is elicited in mice by the irradiated cercaria vaccine and interferon-gamma (IFN-gamma) is a key cytokine in the pulmonary effector response. The role of this cytokine has been investigated in mice with a targeted disruption of the IFN-gamma receptor gene (IFN-gam
Cultured human Langerhans' cells are superior to fresh cells at presenting native HIV-1 protein antigens to specific CD4+ T-cell lines.: Immunology. 1996 Feb;87(2):310-6. Unique Identifier : AIDSLINE MED/96245987; Girolomoni G; Valle MT; Zacchi V; Costa MG; Giannetti A; Manca F; Istituto Dermopatico dell'Immacolata, IRCCS, Rome, Italy.; Cultured Langerhans cells (CLC) exhibit enhanced antigen-presenting function compared to freshly isolated LC (FLC), but they are commonly believed to be inefficient at processing intact proteins. In this study, FLC and CLC from normal, human immunodeficiency virus (HIV) seronegative volunteers were compared for their
Characterization of T cells that confer a high degree of protective immunity against tuberculosis in mice after vaccination with tumor cells expressing mycobacterial hsp65.: Infect Immun. 1996 Jul;64(7):2400-7. Unique Identifier : AIDSLINE MED/96294743; Silva CL; Silva MF; Pietro RC; Lowrie DB; Department of Parasitology, Microbiology and Immunology, School; of Medicine of Ribeirao Preto, University of Sao Paulo, Brazil.; Mice vaccinated by injection with tumor cells expressing the Mycobacterium leprae gene for hsp65 acquire a remarkably high degree of protection against challenge with Mycobacterium tuberculosis. We used limiting-dilution analysis to assess the frequency of CD4+ CD8- and CD4- CD8+ splenocytes responding to mycobacteria
Melanin, melanin ghosts, and melanin composition in Cryptococcus neoformans.: Infect Immun. 1996 Jul;64(7):2420-4. Unique Identifier : AIDSLINE MED/96294746; Wang Y; Aisen P; Casadevall A; Department of Microbiology and Immunology, Albert Einstein; College of Medicine, Bronx, New York 10461, USA.; Melanin synthesis is associated with virulence for the pathogenic fungus Cryptococcus neoformans. Exposure of nonmelanized C. neoformans 4067 cells to 4 M guanidinium isothiocyanate followed by 6 M HCl at 100 degrees C resulted in complete solubilization of cellular structures. However, exposure of melanized C. neofor
Immunity to Cryptosporidium muris infection in mice is expressed through gut CD4+ intraepithelial lymphocytes.: Infect Immun. 1996 Jul;64(7):2556-62. Unique Identifier : AIDSLINE MED/96294764; McDonald V; Robinson HA; Kelly JP; Bancroft GJ; Department of Clinical Sciences, London School of Hygiene and; Tropical Medicine, London, United Kingdom.; The role of gut intraepithelial lymphocytes (IEL) in immunity to cryptosporidial infection was investigated with a murine infection model involving Cryptosporidium muris. Oocyst shedding was monitored in severe combined immunodeficiency (SCID) mice infected with C. muris following intravenous injection of mesenteric l
Tumor necrosis factor alpha and interleukin-12 contribute to resistance to the intracellular bacterium Brucella abortus by different mechanisms.: Infect Immun. 1996 Jul;64(7):2782-6. Unique Identifier : AIDSLINE MED/96294793; Zhan Y; Liu Z; Cheers C; Department of Microbiology, University of Melbourne, Parkville,; Victoria, Australia.; Both interleukin-12 (IL-12) and tumor necrosis factor alpha (TNF-alpha) are produced early in intracellular bacterial infection. Depletion of either IL-12 or TNF-alpha by a single injection of specific antibody 4 h before the injection of Brucella abortus 19 led to the exacerbation of infection 2 weeks later. Whereas
Colocalisation of human immunodeficiency virus and human cytomegalovirus infection in brain autopsy tissue from AIDS patients.: Ir J Med Sci. 1996 Apr-Jun;165(2):133-8. Unique Identifier : AIDSLINE MED/96293026; Balluz IM; Farrell MA; Kay E; Staunton MJ; Keating JN; Sheils O; Cosby SL; Mabruk MJ; Sheahan BJ; Atkins GJ; Department of Microbiology, Moyne Institute of Preventive; Medicine, Trinity College, Dublin, Northern Ireland.; We have examined 26 human AIDS brains obtained at post mortem for infection by human immunodeficiency virus (HIV) and human cytomegalovirus (HCMV), and for dual infection of cells by both viruses. The techniques used were enzyme-linked immunocytochemistry for HCMV and in situ hybri
Interviews with home health aides caring for people with AIDS [interview]: Home Healthc Nurse. 1995 Nov-Dec;13(6):20-4. Unique Identifier : AIDSLINE MED/96329954; Beschle JC; Beggs CM; Russell GE; Through a phenomenological perspective, this study describes the experiences of home health aides caring for people with acquired immunodeficiency syndrome. Six home health aides were asked the question, What is it like to be a home health aide caring for persons with acquired immunodeficiency syndrome? The essential
Kinetic characterization of human immunodeficiency virus type-1 protease-resistant variants.: J Biol Chem. 1996 Jul 26;271(30):17979-85. Unique Identifier : AIDSLINE MED/96279343; Pazhanisamy S; Stuver CM; Cullinan AB; Margolin N; Rao BG; Livingston DJ; Vertex Pharmaceuticals Incorporated, Cambridge, Massachusetts; 02139, USA.; Passage of human immunodeficiency virus type-1 (HIV-1) in T-lymphocyte cell lines in the presence of increasing concentrations of the hydroxylethylamino sulfonamide inhibitor VX-478 or VB-11328 results in sequential accumulation of mutations in HIV-1 protease. We have characterized recombinant HIV-1 proteases that con
A synthetic conformational epitope from the C4 domain of HIV Gp120 that binds CD4.: J Biol Chem. 1996 Jul 26;271(30):17990-5. Unique Identifier : AIDSLINE MED/96279345; Robey FA; Harris-Kelson T; Robert-Guroff M; Batinic D; Ivanov B; Lewis MS; Roller PP; Peptide and Immunochemistry Unit, NIDR, National Institutes of; Health Bethesda, Maryland 20892, USA.; The fourth conserved domain of the human immunodeficiency virus type 1 (HIV-1) envelope, the C4 region of glycoprotein 120 (gp120), is believed to be a major part of gp120 that is necessary for binding to CD4. Recently, we found that C4 in gp120 is probably an alpha-helix, because antibodies made against helical const
A20 blocks endothelial cell activation through a NF-kappaB-dependent mechanism.: J Biol Chem. 1996 Jul 26;271(30):18068-73. Unique Identifier : AIDSLINE MED/96279354; Cooper JT; Stroka DM; Brostjan C; Palmetshofer A; Bach FH; Ferran C; Sandoz Center for Immunobiology, Deaconess Hospital, Harvard; Medical School, Boston, Massachusetts 02215, USA.; The A20 gene product is a novel zinc finger protein originally described as a tumor necrosis factor alpha (TNF)-inducible early response gene in human umbilical vein endothelial cells (HUVEC). Its described function is to block TNF-induced apoptosis in fibroblasts and B lymphocytes, but more recently it has also been
Analysis of T cell receptor V beta expression in rabbit T lymphocytes induced to proliferate by an HTLV-I-transformed leukemogenic T cell line.: J Cancer Res Clin Oncol. 1996;122(8):458-64. Unique Identifier : AIDSLINE MED/96328340; Isono T; Isegawa Y; Seto A; Department of Microbiology, Shiga University of Medical Science,; Japan.; Peripheral blood lymphocytes (PBL) from rabbits of the Chbb:HM strain proliferated in coculture with an X-ray-irradiated HTLV-I-transformed leukemogenic cell line of (B/J x Chbb:HM) F1 origin, whereas PBL from rabbits of the B/J and F1 strains hardly proliferated at all in co-culture with the same cell line. A provira
Activation of antigen-induced lymphocyte proliferation by interleukin-15 without the mitogenic effect of interleukin-2 that may induce human immunodeficiency virus-1 expression.: J Clin Invest. 1996 Aug 1;98(3):616-21. Unique Identifier : AIDSLINE MED/96326385; Patki AH; Quinones-Mateu ME; Dorazio D; Yen-Lieberman B; Boom WH; Thomas EK; Lederman MM; Department of Medicine, Case Western Reserve University School of; Medicine, University Hospitals of Cleveland, Ohio 44106, USA.; The newly identified cytokine, IL-15 enhanced antigen-induced proliferation of PBMC obtained from HIV-1-seropositive subjects. When compared to IL-2 which enhanced both spontaneous and antigen-induced lymphocyte proliferative responses, IL-15 rarely increased spontaneo
Pathogenic and protective correlates of T cell proliferation in AIDS. HNRC Group. HIV Neurobehavioral Research Center.: J Clin Invest. 1996 Aug 1;98(3):731-40. Unique Identifier : AIDSLINE MED/96326399; Schrier RD; Wiley CA; Spina C; McCutchan JA; Grant I; Department of Pathology, University of California, San Diego, La; Jolla 92093, USA. rschrier@ucsd.edu; To investigate the association of antigen specific CD4 T cell activation with HIV disease progression and AIDS-related central nervous system damage, T cell proliferation responses to HIV, CMV , and HSV were evaluated in infected individuals. CD4 T cell loss and
Widespread cutaneous bacillary angiomatosis and a large fungating mass in an HIV-positive man.: J Am Acad Dermatol. 1996 Aug;35(2 Pt 2):285-7. Unique Identifier : AIDSLINE MED/96319544; Fagan WA; DeCamp NC; Kraus EW; Pulitzer DR; University of Texas Health Science Center, Division of; Dermatology, San Antonio 78284-7876, USA.; Bacillary angiomatosis (BA), an infection caused by a gram-negative rod, can be a multiorgan disease. The usual causative organism, Bartonella (formerly Rochalimaea) hensalae, has only recently been identified. Bartonella quintana has also been shown to cause some cases of cutaneous BA. We describe a patient with wide
Photoaccentuated erythroderma associated with CD4+ T lymphocytopenia: successful treatment with 5-methoxypsoralen and UVA, interferon alfa-2b, and extracorporeal photopheresis.: J Am Acad Dermatol. 1996 Aug;35(2 Pt 2):291-4. Unique Identifier : AIDSLINE MED/96319546; Wolf P; Mullegger R; Cerroni L; Aigner R; Fueger G; Hofler G; Derbaschnig J; Kerl H; Department of Dermatology, Karl Franzens University, Graz,; Austria.; We describe a 53-year-old HIV-negative white man who had chronic CD4+ T lymphocytopenia and photoaccentuated erythroderma with lymphoma-like histologic changes. The erythroderma completely responded to 5-methoxypsoralen and UVA (PUVA), interferon alfa-2b, and extracorporeal photopheresis. During therapy opportunistic
Leishmaniasis presenting as a dermatomyositis-like eruption in AIDS.: J Am Acad Dermatol. 1996 Aug;35(2 Pt 2):316-9. Unique Identifier : AIDSLINE MED/96319553; Dauden E; Penas PF; Rios L; Jimenez M; Fraga J; Alvar J; Garcia-Diez A; Department of Dermatology, Hospital de la Princesa, Universidad; Autonoma, Madrid, Spain.; Three patients are described with leishmaniasis and AIDS, with cutaneous lesions mimicking dermatomyositis. Leishmania organisms were observed in great numbers in the dermis of lesional skin biopsy specimens. They were also present inside keratinocytes in all layers of the epidermis in one patient. Skin cultures from
Those who have will, those who haven't won't: caring for HIV-positive patients.: J Contin Educ Nurs. 1996 Mar-Apr;27(2):80-4. Unique Identifier : AIDSLINE MED/96329987; Dols CL; Bradley-Magnuson L; Nurses willingness to care for HIV-positive patients continues to be an issue since the inception of the HIV pandemic. This descriptive correlational study found that while nurses fear of contagion has decreased their willingness to care has not increased in the same proportion. Furthermore, while formal education d
Fever in patients with HIV infection.: Infect Dis Clin North Am. 1996 Mar;10(1):149-65. Unique Identifier : AIDSLINE MED/96244917; Sullivan M; Feinberg J; Bartlett JG; Johns Hopkins University School of Medicine, Baltimore, Maryland,; USA.; Fever is a common sign during the course of HIV infection, usually represents a superimposed opportunistic infection, and is almost always a treatable condition. Proper management generally requires detection of the underlying cause, and the diagnostic evaluation is largely driven by the clinical symptoms, associated
Construction of recombinant extended single-chain antibody peptide conjugates for use in the diagnosis of HIV-1 and HIV-2.: J Immunol Methods. 1996 Jun 10;192(1-2):13-23. Unique Identifier : AIDSLINE MED/96269541; Coia G; Hudson PJ; Lilley GG; CSIRO Division of Biomolecular Engineering, Parkville, Australia.; The construction, expression and evaluation of recombinant scFv based HIV diagnostic reagents are described. In a whole-blood, erythrocyte agglutination assay format, recombinant scFv antibodies (expressed in Escherichia coli), linked to a spacer domain and HIV-gp36 or -gp41 peptides, were shown to be able to detect e
A fluorescent in situ hybridization method in flow cytometry to detect HIV-1 specific RNA.: J Immunol Methods. 1996 Jun 21;193(2):167-76. Unique Identifier : AIDSLINE MED/96269536; Borzi RM; Piacentini A; Monaco MC; Lisignoli G; Degrassi A; Cattini L; Santi S; Facchini A; Laboratorio di Immunologia e Genetica, Istituto di Ricerca; Codivilla Putti, I.O.R., Bologna, Italy.; In HIV+ patients, the presence of HIV-RNA in plasma and circulating cells has been reported to be a marker of progression but the percentage of transcriptionally active infected cells remains unclear. We have developed a reliable fluorescent in situ hybridization method for the detection of HIV specific RNA by flow cy
Present-day management of pulmonary tuberculosis.: J Indian Med Assoc. 1995 Apr;93(4):144-8. Unique Identifier : AIDSLINE MED/96319858; Kundu AK; Kundu AK; Department of Medicine, NRS Medical College, Calcutta.
Detection of human herpesvirus 8 DNA sequences before the appearance of Kaposi's sarcoma in human immunodeficiency virus (HIV)-positive subjects with a known date of HIV seroconversion.: J Infect Dis. 1996 Aug;174(2):283-7. Unique Identifier : AIDSLINE MED/96313003; Lefrere JJ; Meyohas MC; Mariotti M; Meynard JL; Thauvin M; Frottier J; Institut National de Transfusion Sanguine and Service des; Maladies, Infectieuses, Hopital Saint-Antoine, Paris, France.; The presence of human herpesvirus 8 (HHV-8) DNA sequences was sought by polymerase chain reaction (PCR) in peripheral blood mononuclear cells of 4 groups: 6 human immunodeficiency virus (HIV)-infected persons with well-defined dates of seroconversion, during the period between the diagnosis of HIV infection and the ap
Virologic markers of human immunodeficiency virus type 1 in cerebrospinal fluid of infected children.: J Infect Dis. 1996 Aug;174(2):288-93. Unique Identifier : AIDSLINE MED/96313004; Pratt RD; Nichols S; McKinney N; Kwok S; Dankner WM; Spector SA; Department of Pediatrics, University of California, San Diego, La; Jolla 92093-0672, USA.; To identify virologic correlates associated with central nervous system (CNS) abnormalities in children infected with human immunodeficiency virus type 1 (HIV-1), cerebrospinal fluid (CSF) was examined for virologic markers and correlated with neurodevelopmental status and neuroimaging abnormalities. Of 30 children, 1
Predictive markers of AIDS dementia complex: CD4 cell count and cerebrospinal fluid concentrations of beta 2-microglobulin and neopterin.: J Infect Dis. 1996 Aug;174(2):294-8. Unique Identifier : AIDSLINE MED/96313005; Brew BJ; Dunbar N; Pemberton L; Kaldor J; Department of Neurology, St. Vincent's Hospital, Sydney,; Australia.; A predictive marker for AIDS dementia complex (ADC) in a cohort of neurologically asymptomatic human immunodeficiency virus type 1 (HIV-1)-infected patients with
The effect of latent Mycobacterium tuberculosis infection on human immunodeficiency virus (HIV) disease progression and HIV RNA load among injecting drug users.: J Infect Dis. 1996 Aug;174(2):299-308. Unique Identifier : AIDSLINE MED/96313006; Manoff SB; Farzadegan H; Munoz A; Astemborski JA; Vlahov D; Rizzo RT; Solomon L; Graham NM; Department of Epidemiology, Johns Hopkins University School of; Hygiene and Public Health, Baltimore, Maryland 21205, USA.; To examine the relationship between latent Mycobacterium tuberculosis infection and human immunodeficiency virus (HIV) disease progression, two studies were done among a cohort of HIV-infected injecting drug users. First, the decline in CD4 cell count after baseline tuberculin skin testing was prospectively compared f
An international collaborative study of the effects of coinfection with human T-lymphotropic virus type II on human immunodeficiency virus type 1 disease progression in injection drug users.: J Infect Dis. 1996 Aug;174(2):309-17. Unique Identifier : AIDSLINE MED/96313007; Hershow RC; Galai N; Fukuda K; Graber J; Vlahov D; Rezza G; Klein RS; Des Jarlais DC; Vitek C; Khabbaz R; Freels S; Zuckerman R; Pezzotti P; Kaplan JE; University of Illinois, Chicago College of Medicine and School of; Public Health 60612, USA.; To determine whether human T-lymphotropic virus (HTLV) type II coinfection affects progression of human immunodeficiency virus type 1 (HIV) infection, longitudinal data on 370 HIV-infected injection drug users (IDUs) with known HIV seroconversion dates from four cohort studies were pooled. HTLV infection was determine
Human T lymphocyte virus type I-induced myeloneuropathy in rats: implication of local activation of the pX and tumor necrosis factor-alpha genes in pathogenesis.: J Infect Dis. 1996 Aug;174(2):318-23. Unique Identifier : AIDSLINE MED/96313008; Tomaru U; Ikeda H; Ohya O; Abe M; Kasai T; Yamasita I; Morita K; Wakisaka A; Yoshiki T; Department of Pathology, Hokkaido University School of Medicine; Sapporo, Japan.; The pathogenetic roles of human T lymphocyte virus type I (HTLV-I) and cytokines were investigated in HTLV-I-induced myeloneuropathy in Wistar-King-Aptekman-Hokudai rats. In the nervous system, pX messenger RNAs of HTLV-I were selectively expressed in the diseased spinal cord and peripheral nerves but not in the unaff
Immunoregulation in onchocerciasis: persons with ocular inflammatory disease produce a Th2-like response to Onchocerca volvulus antigen.: J Infect Dis. 1996 Aug;174(2):380-6. Unique Identifier : AIDSLINE MED/96313017; Plier DA; Awadzi K; Freedman DO; Department of Medicine, University of Alabama at Birmingham; 35294-2170, USA.; To examine the role of specific cytokines in mediating the clinical manifestations of human onchocercal disease, microfilariae-positive Ghanaian subjects with inflammatory ocular disease were compared with microfilariae-positive subjects without ocular disease. Onchocerca volvulus antigen (OvAg)-stimulated peripheral
Once-weekly intraocular injections of ganciclovir for maintenance therapy of cytomegalovirus retinitis: clinical and ocular outcome.: J Infect Dis. 1996 Aug;174(2):393-6. Unique Identifier : AIDSLINE MED/96313019; Hodge WG; Lalonde RG; Sampalis J; Deschenes J; Department of Ophthalmology, McGill AIDS Centre, McGill; University, Montreal, Canada.; The clinical course and the outcome of treatment were studied in 40 patients with primary cytomegalovirus ( CMV ) retinitis in 57 eyes. All had received one 14-day course of intravenous ganciclovir and all were free of other en
Changes in virus load markers during AIDS-associated opportunistic diseases in human immunodeficiency virus-infected persons.: J Infect Dis. 1996 Aug;174(2):401-3. Unique Identifier : AIDSLINE MED/96313021; Donovan RM; Bush CE; Markowitz NP; Baxa DM; Saravolatz LD; Department of Internal Medicine, Henry Ford Hospital, Detroit,; Michigan 48202, USA.; Human immunodeficiency virus (HIV) load markers are being used increasingly to monitor disease progression and evaluate antiretroviral therapy. This study examined plasma HIV RNA and p24 antigen levels before, during, and after 15 AIDS-associated opportunistic disease events in patients with AIDS (median CD4 cell coun
Human immunodeficiency virus type 1 kinetics in lymph nodes compared with plasma.: J Infect Dis. 1996 Aug;174(2):404-7. Unique Identifier : AIDSLINE MED/96313022; Lafeuillade A; Poggi C; Profizi N; Tamalet C; Costes O; Department of Infectious Diseases, General Hospital, Toulon,; France.; As lymphoid organs are the major reservoir of human immunodeficiency virus type 1 (HIV-1), the rates at which HIV-1 RNA decreases from the plasma and from a series of lymph node biopsies from 4 patients treated with a combination of zidovudine, didanosine, and lamivudine were measured. The concentrations of HIV-1 RNA
An immunohistochemical analysis of naturally occurring chancroid.: J Infect Dis. 1996 Aug;174(2):427-30. Unique Identifier : AIDSLINE MED/96313029; King R; Gough J; Ronald A; Nasio J; Ndinya-Achola JO; Plummer F; Wilkins JA; Department of Pathology, University of Manitoba, Winnipeg,; Canada.; Haemophilus ducreyi is a major cause of genital ulcer disease in many developing countries and is associated with augmented transmission of human immunodeficiency virus (HIV). However, the mechanisms through which H. ducreyi produces ulceration are poorly understood. The characteristics of the host response to H. ducr
Genital ulcers associated with human immunodeficiency virus-related immunosuppression [letter]: J Infect Dis. 1996 Aug;174(2):445-7. Unique Identifier : AIDSLINE MED/96313034; O'Farrell N
Human immunodeficiency virus (HIV) type 1-specific B cell response in seronegative subjects at risk for HIV exposure [letter]: J Infect Dis. 1996 Aug;174(2):447-8. Unique Identifier : AIDSLINE MED/96313035; Angarano G; Fiore JR; Di Stefano M; Monno L
Zidovudine resistance reverse transcriptase mutations during didanosine monotherapy [letter]: J Infect Dis. 1996 Aug;174(2):448-9. Unique Identifier : AIDSLINE MED/96313036; Shafer RW; Winters MA; Jellinger RM; Merigan TC
HIV, TB, and mental illness in a health clinic for the homeless.: J La State Med Soc. 1996 Jun;148(6):267-70. Unique Identifier : AIDSLINE MED/96293114; Townsend MH; Stock MS; Morse EV; Simon PM; LSU School of Medicine, Dept. of Psychiatry, New Orleans, USA.; The authors reviewed the medical records of both mentally ill and non-mentally ill patients in a clinic for the homeless population of New Orleans. The records of all psychiatric patients (n = 52) and a randomly selected comparison group (n = 236) of clinic patients without mental illness were chosen for review. Five
The inflammatory macrophage response to MCMV in mice with a retroviral immunodeficiency syndrome (MAIDS).: J Leukoc Biol. 1996 Jul;60(1):44-50. Unique Identifier : AIDSLINE MED/96295956; Allcock RJ; Peacock CD; Price P; Department of Microbiology, University of Western Australia,; Nedlands, Australia.; We have shown that normal C57BL/6J mice are moderately resistant to infection with murine cytomegalovirus (MCMV) and that this resistance is impaired by prior infection with LP-BM5 MuLV, which causes a disease (MAIDS) similar to early HIV-induced disease. This study investigates ma
Characterization of antisense RNA-mediated inhibition of SIV replication.: J Med Virol. 1996 Apr;48(4):321-5. Unique Identifier : AIDSLINE MED/96258547; Tung FY; Tung MH; Department of Infectious Diseases and Microbiology, Graduate; School of Public Health, University of Pittsburgh, PA 15261, USA.; Antisense RNA-mediated inhibition of HIV showed mixed success in previous experiments. In order to elucidate the parameters influencing the efficacy of an antisense RNA approach, retroviral vectors encoding 4.5 kb, 3.5 kb, or 2.5 kb antisense RNA of the gag-pol region of SIV (simian immunodeficiency virus) were constr
Hepatitis C plasma viral load is associated with HCV genotype but not with HIV coinfection.: J Med Virol. 1996 Apr;48(4):339-43. Unique Identifier : AIDSLINE MED/96258550; Berger A; von Depka Prondzinski M; Doerr HW; Rabenau H; Weber B; Institut fur Medizinische Virologie, Universitatskliniken; Frankfurt, a. M., Germany.; The influence of human immunodeficiency virus (HIV) coinfection and hepatitis C virus (HCV) genotype distribution on HCV viral load and alanine amino transferase (ALT) levels in chronically infected patients remains unclear. In the present study, serum samples from a group of haemophiliac patients were investigated re
Human herpesvirus 6 in human immunodeficiency virus-infected individuals: association with early histologic phases of lymphadenopathy syndrome but not with malignant lymphoproliferative disorders.: J Med Virol. 1996 Apr;48(4):344-53. Unique Identifier : AIDSLINE MED/96258551; Dolcetti R; Di Luca D; Carbone A; Mirandola P; De Vita S; Vaccher E; Sighinolfi L; Gloghini A; Tirelli U; Cassai E; Boiocchi M; Department of Experimental Oncology, INRCCS, Aviano (PN), Italy.; Preliminary evidence suggested that human herpesvirus-6 (HHV-6) may act as a cofactor in acquired immunodeficiency syndrome (AIDS) and may contribute to the pathogenesis of lymphoproliferative disorders occurring in individuals infected with the human immunodeficiency virus (HIV). To understand better the biological a
Viral safety of a new highly purified factor VIII (OCTATE).: J Med Virol. 1996 Apr;48(4):360-6. Unique Identifier : AIDSLINE MED/96258553; Biesert L; Lemon S; Goudeau A; Suhartono H; Wang L; Brede HD; Octapharma AG, Ziegelbrucke, Switzerland.; The inactivation of both transfusion-relevant and model viruses by modified pasteurisation (10 hours at 63 degrees C in solution) has been evaluated following the established guidelines of the EU CPMP Ad Hoc Working Party on Biotechnology/Pharmacy. This heat treatment was introduced into the manufacturing process of O
Antitumor germacranolides from Anvillea garcinii.: J Nat Prod. 1996 Apr;59(4):403-5. Unique Identifier : AIDSLINE MED/96209296; Abdel Sattar E; Galal AM; Mossa GS; Department of Pharmacognosy, College of Pharmacy, King Saud; University, Riyadh Saudi Arabia.; The aerial parts of Anvillea garcinii yielded two new germacranolides, 9 alpha-hydroxy-1 beta, 10 alpha-epoxyparthenolide (4) and parthenolid-9-one (5), in addition to the known 9 alpha-hydroxyparthenolide (1), 9 beta-hydroxyparthenolide (2), and 9 beta-hydroxy-1 beta, 10 alpha-epoxyparthenolide (3). The structures of
On the use of auxiliary data to estimate the survival function and its variance: an application to acquired immunodeficiency syndrome.: J Clin Epidemiol. 1996 Aug;49(8):899-905. Unique Identifier : AIDSLINE MED/96326372; Flandre P; INSERM, Villejuif, France.; Prospective studies have as their goal the estimation of the survival function when the time to the specified event may be censored due to loss to follow-up or to the termination of the study before the event of interest occurs. In such a study, information about an auxiliary event, correlated to the event of interest
Fear of AIDS, homophobia, and occupational risk for HIV. A staff development challenge.: J Nurs Staff Dev. 1995 Nov-Dec;11(6):313-9. Unique Identifier : AIDSLINE MED/96329512; Glad J; Tan WN; Erlen JA; Nursing is committed to providing quality care; however, nursing practice has been challenged by patients with AIDS. In this pilot study, the authors investigated the relation among nurses homophobia, fear AIDS, and occupational risk for contracting HIV. With their findings, they found that a positive attitude toward
Policy and position statement. Pediatric HIV disease. National Association of Pediatric Nurse Associates and Practitioners.: J Pediatr Health Care. 1996 Jan-Feb;10(1):44-5. Unique Identifier : AIDSLINE MED/96334440
Kaposi's sarcoma versus bacillary angiomatosis.: J Am Podiatr Med Assoc. 1996 Jun;86(6):260-2. Unique Identifier : AIDSLINE MED/96280311; Caldwell BD; Kushner D; Young B; Department of Podiatric Medicine, Ohio College of Podiatric; Medicine, Cleveland, USA.; Persons with acquired immune deficiency syndrome (AIDS) are subject to a host of pathologic entities secondary to a depressed immune system. Kaposi s sarcoma frequently presents in this immunocompromised population and, therefore, diagnosis seems clinically straightforward. However, because of the prevalence of a stri
Stand down for the homeless. Podiatric screening of a homeless population in Cleveland.: J Am Podiatr Med Assoc. 1996 Jun;86(6):275-9. Unique Identifier : AIDSLINE MED/96280314; Robbins JM; Roth LS; Villanueva MC; Department of Community Medicine, Ohio College of Podiatric; Medicine, Cleveland 44106, USA.; Health care for the homeless is a major public health concern. With the rise in antibiotic-resistant tuberculosis, the increase of human immunodeficiency virus (HIV) diseases, and other health risks, the medical community has begun to recognize the urgency of taking a proactive role in providing care for this populati
Transposable elements behavior following viral genomic stress in Drosophila melanogaster inbred line.: J Mol Evol. 1996 Jul;43(1):19-27. Unique Identifier : AIDSLINE MED/96304318; Jouan-Dufournel I; Cosset FL; Contamine D; Verdier G; Biemont C; Laboratoire de Biometrie, Genetique et Biologie des; Populations, UMR 5558, Universite Claude Bernard, Lyon 1, 69622; Villeurbanne Cedex, France.; To analyze the behavior of endogenous transposable elements under genomic stress, a Drosophila melanogaster inbred line was submitted to three kinds of viral perturbations. First, a retroviral plasmid containing the avian Rous Associated Virus type 2 (RAV-2) previously deleted for the viral envelope coding gene (env)
AIDS prevention in high-risk African American women: behavioral, psychological, and gender issues.: J Sex Marital Ther. 1996 Spring;22(1):9-21. Unique Identifier : AIDSLINE MED/96317937; Hetherington SE; Harris RM; Bausell RB; Kavanagh KH; Scott DE; University of Maryland at Baltimore School of Nursing 21230, USA.; A three-year longitudinal intervention study was implemented to reduce high-risk drug and sexual behaviors in methadone-dependent African American women. Participants were recruited from four inner-city methadone maintenance programs and randomly assigned either to an eight-week peer counseling and leadership training
Hepatitis, rash and eosinophilia following trichloroethylene exposure: a case report and speculation on mechanistic similarity to halothane induced hepatitis.: J Toxicol Clin Toxicol. 1996;34(4):461-6. Unique Identifier : AIDSLINE MED/96323007; Bond GR; Department of Emergency Medicine, University of Virginia,; Charlottesville 22908, USA.; CASE REPORT: A previously healthy 30-year-old male began work as a degreaser. The solvent used in the degreasing operation was trichloroethylene. Over the next month he experienced symptoms of weakness, dizziness, decreased appetite, nausea, abdominal pain, diarrhea, fever, chills, dry skin, red rash with bumps, peeli
[10th International Conference on AIDS in Yokohama]: Kango. 1994 Oct;46(12):164-72. Unique Identifier : AIDSLINE MED/96330040; Ishihara M
[Nursing care of patients with AIDS and education of nurses at Hospital Cochin in Paris: hospital organization]: Kango. 1994 Oct;46(12):173-83. Unique Identifier : AIDSLINE MED/96330041; Shimizu A
[Nursing care of patients with AIDS and education of nurses at Hospital Cochin in Paris: telling diagnosis, wearing gloves]: Kango. 1994 Nov;46(13):184-93. Unique Identifier : AIDSLINE MED/96330062; Shimizu A
[Human rights of AIDS patients and international collaboration. WHO Nursing Collaborative Center]: Kango. 1994 Nov;46(13):216-9. Unique Identifier : AIDSLINE MED/96330065
[Increased possibility for HIV-associated retinal microangiopathy syndrome in patients with concomitant hepatitis C infection]: Klin Monatsbl Augenheilkd. 1996 Mar;208(3):157-60. Unique Identifier : AIDSLINE MED/96237318; Thierfelder S; Linnert D; Universitats-Augenklinik Wurzburg.; BACKGROUND: The etiology of HIV-related retinal microangiopathy syndrome is yet unknown. Several authors postulate direct endothelial-cell infection, an immunocomplex vasculitis caused by HIV-related hypergammaglobulinemia or an increased serum concentration of endothelin as its origin. PATIENTS: 118 patients infected
Pentoxifylline for the treatment of HIV infection and its complications.: J Cardiovasc Pharmacol. 1995;25 Suppl 2:S139-42. Unique Identifier : AIDSLINE MED/96234442; Dezube BJ; Lederman MM; Department of Medicine, Beth Israel Hospital, Harvard Medical; School, Boston, Massachusetts 02215, USA.; The increased levels of tumor necrosis factor-alpha (TNF-alpha) seen in patients with acquired immune deficiency syndrome (AIDS) may contribute to the AIDS-related wasting syndrome. TNF also induces expression of human immunodeficiency virus (HIV) through activation of the transcription factor NF-kappa B, which binds
Impairment of polymorphonuclear neutrophil function in HIV-infected patients.: J Cardiovasc Pharmacol. 1995;25 Suppl 2:S66-70. Unique Identifier : AIDSLINE MED/96234427; Elbim C; Prevot MH; Bouscarat F; Franzini E; Chollet-Martin S; Hakim J; Gougerot-Pocidalo MA; INSERM U294, Paris, France.; Impaired polymorphonuclear neutrophil (PMN) function may contribute to the onset of certain bacterial and fungal infections and to tissue damage in human immunodeficiency virus (HIV)-infected patients. Published data on PMN function in HIV infection are controversial, possibly because most studies have involved PMNs i
Production of proinflammatory cytokines and cytokines involved in the TH1/TH2 balance is modulated by pentoxifylline.: J Cardiovasc Pharmacol. 1995;25 Suppl 2:S80-4. Unique Identifier : AIDSLINE MED/96234430; Bienvenu J; Doche C; Gutowski MC; Lenoble M; Lepape A; Perdrix JP; Laboratoire d'Immunologie, Centre Hospitalier Lyon-Sud, Pierre; Benite, France.; The modulation of cytokine release induced by pentoxifylline (PTX) has recently been demonstrated not to be restricted solely to tumor necrosis factor (TNF)-alpha. This prompted us to study the influence of PTX on a larger spectrum of cytokines with proinflammatory actions [TNF-alpha, interleukin-6, (IL)-6, IL-1 beta,
Microsporidian sinusitis in patients with the acquired immunodeficiency syndrome.: Laryngoscope. 1996 Aug;106(8):966-71. Unique Identifier : AIDSLINE MED/96320334; Rossi RM; Wanke C; Federman M; Harvard Medical School, Boston, MA USA.; Sinusitis in patients with human immunodeficiency virus (HIV) infection usually arises from the same organisms that are infective in the nonimmunosuppressed population. The authors of this article report that optimal antimicrobial treatment and functional endoscopic sinus surgery failed to eradicate sinonasal disease
Safety awareness for the otolaryngologist caring for the HIV-positive patient.: Laryngoscope. 1996 Aug;106(8):982-6. Unique Identifier : AIDSLINE MED/96320337; Kantu S; Lee D; Nash M; Lucente FE; Department of Otolaryngology, University Hospital of Brooklyn,; New York, USA.; The alarming increase in human immunodeficiency virus (HIV) infection, expected to reach 40 million cases worldwide by the year 2000, has enormous impact on the otolaryngologist, since up to 70% of HIV-positive patients present with head and neck symptoms. Parenteral and nonparenteral acquisition of HIV has been docum
Sulfadiazine-associated nephrotoxicity in patients with the acquired immunodeficiency syndrome.: Medicine (Baltimore). 1996 Jul;75(4):185-94. Unique Identifier : AIDSLINE MED/96320354; Becker K; Jablonowski H; Haussinger D; Department of Gastroenterology and Infectious Diseases, Heinrich; Heine University Medical Center, Dusseldorf, Germany.; We performed a computerized search on sulfadiazine-associated nephrotoxicity reported in human immunodefiency virus (HIV)-infected patients in the international literature. Including an original case report, we summarized 35 acquired immunodefiency syndrome (AIDS) patients from 1987 to 1995 in an analysis comparing th
Mandatory HIV testing of patients and professionals: bringing ethics into practice.: Med Educ. 1995 Sep;29(5):360-3. Unique Identifier : AIDSLINE MED/96286890; Berglund CA; School of Community Medicine, University of New South Wales,; Australia.; A contemporary health dilemma, that of mandatory HIV testing of patients and professionals, is used as a focus for an ethics class. Background material which is given to students is described and referenced. The interjection of ethical theory is described. The exercise has provided an effective focus for medical and h
2',3'-Didehydro-3'-deoxythymidine: regulation of its metabolic activation by modulators of thymidine-5'-triphosphate biosynthesis.: Mol Pharmacol. 1996 Jul;50(1):160-5. Unique Identifier : AIDSLINE MED/96295589; Ahluwalia GS; Gao WY; Mitsuya H; Johns DG; Laboratory of Medicinal Chemistry, National Cancer Institute,; National Institutes of Health, Bethesda, Maryland 20892-4255,; USA.; The anti-human immunodeficiency virus (anti-HIV) agent 2 ,3 -didehydro-3 -deoxythymidine (D4T), like other 2 ,3 -dideoxynucleosides, requires conversion to its 5 -triphosphate to exert its pharmacological effect. Although D4T-triphosphate is unusually potent as an inhibitor of HIV-1 reverse transcriptase, the phosphor
Ligands of the antiestrogen-binding site are able to inhibit virion production of human immunodeficiency virus 1-infected lymphocytes.: Mol Pharmacol. 1996 Jul;50(1):75-9. Unique Identifier : AIDSLINE MED/96295579; Mesange F; Delarue F; Puel J; Bayard F; Faye JC; Laboratoire d'Endocrinoldgie et Communication Cellulaire, INSERM; U397, Institut Louis Bugnard, CHU Rangueil, Toulouse, France.; Since the discovery of human immunodeficiency retrovirus, the drug arsenal against retrovirus has rapidly increased. Concomitantly, new challenges in the therapy of acquired immune deficiency syndrome have arisen, including drug toxicities, drug resistance, and the development of various cancers as effective therapies
Potent inhibition of human immunodeficiency virus and herpes simplex virus type 1 by 9-(2-phosphonylmethoxyethyl)adenine in primary macrophages is determined by drug metabolism, nucleotide pools, and cytokines.: Mol Pharmacol. 1996 Aug;50(2):359-66. Unique Identifier : AIDSLINE MED/96319786; Perno CF; Balestra E; Aquaro S; Panti S; Cenci A; Lazzarino G; Tavazzi B; Di Pierro D; Balzarini J; Calio R; Department of Experimental Medicine and Biochemical Sciences,; University of Rome Tor Vergata, Italy. perno@tovvx1.ccd.utovrm.it; The efficacy of 9-(2-phosphonylmethoxyethyl)adenine (PMEA) against the replication of human immunodeficiency virus (HIV) and herpes simplex virus type 1 (HSV-1) and its cellular metabolism were investigated in human primary macrophages from seronegative donors. PMEA potently inhibited the replication of both HIV and H
Highly favorable antiviral activity and resistance profile of the novel thiocarboxanilide pentenyloxy ether derivatives UC-781 and UC-82 as inhibitors of human immunodeficiency virus type 1 replication.: Mol Pharmacol. 1996 Aug;50(2):394-401. Unique Identifier : AIDSLINE MED/96319790; Balzarini J; Pelemans H; Aquaro S; Perno CF; Witvrouw M; Schols D; De Clercq E; Karlsson A; Rega Institute for Medical Research, Katholieke Universiteit; Leuven, Belgium. jan.balzarini@rega.kuleuven.ac.be; The novel human immunodeficiency virus type 1-specific thiocarboxanilide derivatives that contain either a substituted furanyl (UC-781) or thienyl (UC-82) ring linked to the thiocarboxy group and a pentenyloxyether chain linked to the 4-chlorophenyl ring in meta position show highly favorable antiviral properties. Com
'Beware of hype,' AIDS conference told [news]: Nature. 1996 Jul 11;382(6587):101. Unique Identifier : AIDSLINE MED/96317575; Macilwain C
Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice.: Nature. 1996 Jul 11;382(6587):174-7. Unique Identifier : AIDSLINE MED/96317591; Kaplan MH; Sun YL; Hoey T; Grusby MJ; Department of Cancer Biology, Harvard School of Public Health,; Boston, Massachusetts 02115, USA.; Interactions between cytokine and receptor lead to the activation of multiple signalling molecules, including the family of signal transducer and activator of transcription (STAT) proteins. STAT4 is one member of this family, and is activated only in response to the cytokine interleukin (IL)-12 (refs 5, 6). By gene ta
Unpublished findings not intended for reference [letter]: Mil Med. 1996 Jun;161(6):A4-5. Unique Identifier : AIDSLINE MED/96267924; Temoshok LR
[Visceral leishmaniasis in patients with HIV infection. Our experience]: Minerva Med. 1996 Jun;87(6):317-9. Unique Identifier : AIDSLINE MED/96314389; Terra L; Pellicano S; Allo M; Divisione Malattie Infettive, Ospedale S. Giovanni di Dio, USL n.; 5, Crotone.; The authors describe a case of visceral leishmaniasis in an intravenous drug abuser, HIV seropositive patient. Visceral leishmaniasis was the first opportunist infection and diagnosis was based on smear from bone marrow. A treatment with N-methylglucamine and allopurinol was successful. The authors stress to take into
The effects of an AIDS diagnosis on undergraduate nursing students' care of dying patients.: Nurse Educ. 1995 Nov-Dec;20(6):15-21. Unique Identifier : AIDSLINE MED/96335530; Bormann JE; Brent SB; Mood DW; Nurse educators frequently deal with nursing students discomfort in learning to care for dying patients. However, teaching students how to care for dying patients with acquired immune deficiency syndrome (AIDS) presents unique and interesting challenges. The authors describe the influence an AIDS diagnosis has on stu
Constitutively activated JNK is associated with HTLV-1 mediated tumorigenesis.: Oncogene. 1996 Jul 4;13(1):135-42. Unique Identifier : AIDSLINE MED/96292235; Xu X; Heidenreich O; Kitajima I; McGuire K; Li Q; Su B; Nerenberg M; Department of Molecular and Experimental Medicine, The Scripps; Research Institute, La Jolla, California 92307, USA.; Human T cell leukemia virus type I (HTLV-1) is the etiologic agent of adult T-cell leukemia (ATL) and HTLV-1 associated myelopathy, also called tropical spastic paraparesis (HAM/TSP). Both clinical and in vitro evidence have demonstrated that the virus or its transactivator Tax, are transforming. However, transformati
Tuberculosis and multi-drug resistant tuberculosis in children.: Pediatr Nurs. 1995 Nov-Dec;21(6):566-72. Unique Identifier : AIDSLINE MED/96334600; Peloquin CA; Berning SE; Infection and disease caused by Mycobacterium tuberculosis remain a hugh global problem, and are not well controlled in several areas within the United States . Co-infection with the human immunodeficiency virus (HIV) and immigration from areas with high rates of tuberculosis contribute
The influence of stress management training in HIV disease.: Nurs Res. 1996 Jul-Aug;45(4):246-53. Unique Identifier : AIDSLINE MED/96314397; McCain NL; Zeller JM; Cella DF; Urbanski PA; Novak RM; Department of Adult Health Nursing, School of Nursing, Virginia; Commonwealth University, Richmond, USA.; A pretest-posttest design (with a 6-week wait-list control and a 6-month comparison group) was used to compare the effectiveness of a 6-week stress management training program with standard outpatient care for 45 men with HIV disease. Outcomes included stress levels, coping patterns, quality of life, psychological dis
HIV/AIDS predictions proved wrong [news]: Nurs Times. 1996 Feb 14-20;92(7):9. Unique Identifier : AIDSLINE MED/96329261; Cassidy J
Evaluation of shared care for people with HIV [news]: Nurs Times. 1996 Feb 28-Mar 5;92(9):12. Unique Identifier : AIDSLINE MED/96334566; Smith S; Robinson J; Hollyer J
Alopecia associated with zidovudine therapy.: Pharmacotherapy. 1996 Jan-Feb;16(1):79-81. Unique Identifier : AIDSLINE MED/96286322; Geletko SM; Segarra M; Mikolich DJ; Department of Pharmacy Practice, University of Rhode Island; College of Pharmacy, Providence, 02908, USA.; Alopecia has been described in patients infected with the human immunodeficiency virus (HIV). Zidovudine reportedly influences hair growth in these patients, causing regrowth or thickening. A 33-year-old HIV-infected man developed alopecia areata after beginning zidovudine therapy. The alopecia reversed after the drug
Infectious myositis. A tropical disease steals out of its zone.: Postgrad Med. 1996 Aug;100(2):193-4, 199-200. Unique Identifier : AIDSLINE MED/96323051; O'Neill DS; Baquis G; Moral L; Department of Internal Medicine, Baystate Medical Center,; Springfield, MA 01199, USA.; Infectious myositis is an acute infection of skeletal muscle that is increasing in prevalence with the increased incidence of HIV disease. Typical presentation is asymmetric swelling of an isolated muscle, with exquisite pain and fever. Results of laboratory studies are usually nonspecific, but magnetic resonance imag
Urticaria. The diagnostic challenge of hives.: Postgrad Med. 1996 Aug;100(2):77-8, 81-4. Unique Identifier : AIDSLINE MED/96323044; Sveum RJ; Department of Allergy, Park Nicollet Clinic, Minneapolis, USA.; Hives pose a diagnostic challenge to physicians. With an acute episode, a careful look for possible triggers and relief of symptoms with H1 antihistamines are usually sufficient. For both urticaria and angioedema, the most helpful diagnostic tool may be a carefully taken medical history, including a family history. Wh
Human immunodeficiency virus type 1 and 2 Tat proteins specifically interact with RNA polymerase II.: Proc Natl Acad Sci U S A. 1996 Mar 5;93(5):2089-94. Unique Identifier : AIDSLINE MED/96312544; Mavankal G; Ignatius Ou SH; Oliver H; Sigman D; Gaynor RB; Division of Molecular Virology, University of Texas Southwestern; Medical Center, Dallas 75235-8594, USA.; The Tat-responsive region (TAR) element is a critical RNA regulatory element in the human immunodeficiency virus (HIV) long terminal repeat, which is required for activation of gene expression by the transactivator protein Tat. Recently, we demonstrated by gel-retardation analysis that RNA polymerase II binds to TAR R
Peptides from conserved regions of paramyxovirus fusion (F) proteins are potent inhibitors of viral fusion.: Proc Natl Acad Sci U S A. 1996 Mar 5;93(5):2186-91. Unique Identifier : AIDSLINE MED/96312562; Lambert DM; Barney S; Lambert AL; Guthrie K; Medinas R; Davis DE; Bucy T; Erickson J; Merutka G; Petteway SR Jr; Trimeris, Inc., Research Triangle Park, NC 27709, USA.; The synthetic peptides DP-107 and DP-178 (T-20), derived from separate domains within the human immunodeficiency virus type 1 (HIV-1) transmembrane (TM) protein, gp4l, are stable and potent inhibitors of HIV-1 infection and fusion. Using a computer searching strategy (computerized antiviral searching technology, C.A.S
Attitudes to drug users according to age of staff.: Prof Nurse. 1996 Mar;11(6):401-2, 404. Unique Identifier : AIDSLINE MED/96327538; Carroll J; The attitudes of professionals working with intravenous drug users, and their perceptions of service delivery, are likely to be affected by age. Younger professionals tend to be more positive in their attitudes towards intravenous drug users. Older professionals tend to be less concerned about the risks from HIV infec
[Rotavirus studied in the feces of 10 patients with the acquired immunodeficiency syndrome (AIDS)]: Rev Soc Bras Med Trop. 1996 May-Jun;29(3):283-4. Unique Identifier : AIDSLINE MED/96244796; Machado AA; Owa MA; de Freitas-Silva G; Figueiredo F de C; Martinez R; Departamento de Clinica Medica, Faculdade de Medicina de; Ribeirao Preto, Universidade de Sao Paulo.
[Cytomegalovirus retinitis in patients with AIDS (editorial)]: Rev Clin Esp. 1996 Apr;196(4):205-7. Unique Identifier : AIDSLINE MED/96254479; Verdejo Ortes J
[Intravitreal ganciclovir in cytomegalovirus retinitis in AIDS]: Rev Clin Esp. 1996 Apr;196(4):208-12. Unique Identifier : AIDSLINE MED/96254480; Olea JL; Salvat M; Mateos JM; Vila J; Villalonga C; Riera M; Servicio de Oftalmologia, Hospital Son Dureta, Palma de; Mallorca.; A retrospective study was made of 26 patients with AIDS who initially presented with retinitis as the only clinical manifestation of cytomegalovirus infection (39 eyes). Sixty-five induction or re-induction therapeutic courses were administered with intravitreal ganciclovir. The ef
[Usefulness of bone marrow examination in patients with advanced HIV infection]: Rev Clin Esp. 1996 Apr;196(4):213-6. Unique Identifier : AIDSLINE MED/96254481; Rodriguez JN; Dieguez JC; Moreno MV; Aguayo DM; Vega MD; Conde J; Prados D; Servicio de Hematologia, Hospital Juan Ramon Jimenez, Huelva.; A bone marrow investigation is a common examination in HIV infected patients for the study of cytopenia, febrile syndromes of unknown origin and extension of neoplastic disorders. A study was made of bone marrow specimens from 35 patients with advanced HIV infection (stage IC or C, CDC, Atlanta) for morphologic and cu
[Cellular immune response in tuberculosis: analysis of T-lymphocytes and their subsets, B-lymphocytes and natural cytotoxic cells in different tuberculosis states and body fluids]: Rev Clin Esp. 1996 Apr;196(4):223-7. Unique Identifier : AIDSLINE MED/96254483; Montes Santiago J; Gambon Deza F; Pacheco Carracedo M; Cerda Mota T; Servicio de Medicina Interna, Hospital de Meixoeiro, Vigo.; BACKGROUND. The immune response to Mycobacterium tuberculosis is primarily mediated by T lymphocytes. In this study an investigation was made of T lymphocytes and their subsets, B lymphocytes and natural cytotoxic cells (Natural Killer, NK) in blood and organic fluids in different tuberculosis conditions. METHODS. Pat
[Treatment of neutropenia in HIV infection with hematopoietic growth factors]: Rev Clin Esp. 1996 Apr;196(4):248-54. Unique Identifier : AIDSLINE MED/96254488; Moreno Garcia M; Fernandez Gonzalez F; Servicio de Medicina Interna, Hospital Penitenciario, Madrid.
[Surgical abdomen in a patient with human immunodeficiency virus infection (clinical conference)]: Rev Clin Esp. 1996 Apr;196(4):264-9. Unique Identifier : AIDSLINE MED/96254495
[Hematopoietic growth factors]: Rev Med Liege. 1996 Jan;51(1):102-6. Unique Identifier : AIDSLINE MED/96308108; Fillet G; Departement de Medecine, Service d'Hematologie, Universite de; Liege.
[Disseminated infection with Mycobacterium celatum]: Schweiz Med Wochenschr. 1996 Jun 15;126(24):1062-5. Unique Identifier : AIDSLINE MED/96271226; Emler S; Praplan P; Rohner P; Auckenthaler R; Hirschel B; Division des maladies infectieuses, Hopitaux universitaires de; Geneve.; A 29-year-old patient with AIDS was hospitalized with weight loss, fever and cough. Mycobacterial cultures from sputum, blood and bronchoalveolar lavage became positive after 3 weeks incubation. When using a DNA probe for identification of Mycobacterium tuberculosis complex, a weakly positive signal was obtained. Tub
[Role of hepatotropic viruses in liver pathology in Southwestern Cameroon]: Schweiz Med Wochenschr Suppl. 1996;79:36S-43S. Unique Identifier : AIDSLINE MED/96251556; Skalsky JA; Joller-Jemelka HI; Bianchi L; Knoblauch M; Presbyterian Medical Institutions Manyemen, SWP, Cameroon.; Between 1990 and 1992 (2 years), 102 patients with clinical liver pathology underwent standardized clinical, pathological, sonographic and serologic investigations (HAV, HBV, HCV, HDV autoantibodies and tumor markers). During the same period seroepidemiological studies with the same parameters as above were performed
HIV's Achilles' heel. Drugs and education are starting to slow the AIDS virus [news]: Sci Am. 1996 Sep;275(3):16, 18. Unique Identifier : AIDSLINE MED/96327163; Beardsley T
New chip off the old block. Can DNA microprobes do for genetics what microprocessors did for computing? [news]: Sci Am. 1996 Sep;275(3):42, 44. Unique Identifier : AIDSLINE MED/96349303; Gibbs WW
Reports bolster viral cause of KS [news]: Science. 1996 Aug 2;273(5275):573. Unique Identifier : AIDSLINE MED/96345541; Cohen J
Fetal immune response [letter]: Science. 1996 Aug 9;273(5276):722-3. Unique Identifier : AIDSLINE MED/96349293; Sarfati M; Delespesse G
Genome sequence of a human tumorigenic poxvirus: prediction of specific host response-evasion genes.: Science. 1996 Aug 9;273(5276):813-6. Unique Identifier : AIDSLINE GENBANK/U60315; Senkevich TG; Bugert JJ; Sisler JR; Koonin EV; Darai G; Moss B; Laboratory of Viral Diseases, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Bethesda, MD; 20892-0455, USA.; Molluscum contagiosum virus (MCV) commonly causes asymptomatic cutaneous neoplasms in children and sexually active adults as well as persistent opportunistic acquired immunodeficiency syndrome (AIDS)-associated disease. Sequencing the 190-kilobase pair genome of MCV has now revealed that the virus potentially encodes
Infection with hepatitis GB virus among Japanese hemophiliacs (letter).: Transfusion. 1996 Jul;36(7):669. Unique Identifier : AIDSLINE MED/96323067; Nishiyama Y; Nakashima H; Hino K; Mori K; Ishikawa M; Okamoto H
[Anus cancer]: Ugeskr Laeger. 1996 Jul 8;158(28):4073-6. Unique Identifier : AIDSLINE MED/96292602; Keldsen N; Laurberg S; Onkologisk afdeling D, Arhus Kommmunehospital.; The pathology, etiology and epidemiology of anal cancer (CA) and the treatment and prognostic factors are reviewed. CA is a rare disease. However, the incidence is rising and is now 0.7 per 100,000 women and 0.4 per 100,000 men in Denma
Serologic evidence for bovine immunodeficiency virus infection in France.: Vet Microbiol. 1996 Jan;48(1-2):165-73. Unique Identifier : AIDSLINE MED/96241245; Polack B; Schwartz I; Berthelemy M; Belloc C; Manet G; Vuillaume A; Baron T; Gonda MA; Levy D; Unite de Recherche Associee d'Immuno-Pathologie Cellulaire et; Moleculaire, Ecole Nationale Veterinaire d'Alfort, France.; We report herein on the first serologic detection of antibodies to bovine immunodeficiency virus (BIV) in France . Serum samples from dairy and beef cattle from southwestern and western France (Landes and Vendee) were tested using a western blot assay with a recombinant 53 kDa gag p
Overview: practical insights from comparative immunology and pathogenesis of AIDS, hepatitis B, and measles for developing an HIV vaccine.: Vaccine. 1995 Dec;13(18):1733-40. Unique Identifier : AIDSLINE MED/96264827; Hilleman MR; Merck Institute for Therapeutic Research, Merck Research; Laboratories, West Point, PA 19486, USA.; Combined effects of viral mutation, beneficial and adverse host immune responses, and alterations in immune function strongly fashion the pathogenesis and outcome of HIV infection. Understanding HIV can be aided by understanding hepatitis B and measles. Clinical remission and exacerbation in persistent hepatitis B vir
Immunization with a soluble recombinant HIV protein entrapped in biodegradable microparticles induces HIV-specific CD8+ cytotoxic T lymphocytes and CD4+ Th1 cells.: Vaccine. 1995 Dec;13(18):1741-9. Unique Identifier : AIDSLINE MED/96264828; Moore A; McGuirk P; Adams S; Jones WC; McGee JP; O'Hagan DT; Mills KH; Biology Department, St. Patrick's College, Maynooth, Co. Kildare,; Ireland.; One of the major obstacles to the development of successful recombinant vaccines against human immunodeficiency virus (HIV) and other intracellular pathogens is the identification of a safe and effective vaccine delivery system for the induction of cell mediated immunity with soluble protein antigens. In this study it
[AIDS prevention in homosexuals in Switzerland: adaptation to risks according to type of partner]: Soz Praventivmed. 1996;41(1):1-10. Unique Identifier : AIDSLINE MED/96317878; Moreau-Gruet F; Dubois-Arber F; Institut universitaire de medecine sociale et preventive,; Lausanne.; OBJECTIVE: To evaluate the effectiveness of AIDS prevention and modes of adaptation to risk among gay men. Swiss results are presented from an international study conducted in 8 European countries. METHOD: A self-administered questionnaire was published in gay magazines and distributed by gay organizations and clubs.
[The effect of streptococcal group A polysaccharide on PHA-induced T-cell proliferation]: Zh Mikrobiol Epidemiol Immunobiol. 1996 Mar-Apr;(2):71-3. Unique Identifier : AIDSLINE MED/96254369; Bazanova EA; Gnezditskaia EV; Nesterenko VG; Popova LK; Sanina VIu; Ignatenko IN; The influence of group A streptococcal polysaccharide (A-PS) on the proliferation and functional activity of subpopulations CD4+ and CD8+ of human peripheral blood lymphocytes has been studied. As revealed in this study, A-PS, though having no mitogenic activity of its own, is capable of influencing the process of pro
AILD-like dysplasia transformed in AILD-type T cell lymphoma in an HTLV-1 carrier: usefulness of interferon-alpha.: Acta Haematol. 1996;96(2):92-8. Unique Identifier : AIDSLINE MED/96328248; Kozuru M; Hashimoto M; Takahira H; Uike N; Ohoshima K; Takeshita M; Kikuchi M; Clinical Research Institute, National Kyushu Cancer Center,; Fukuoka, Japan.; A 61-year-old Japanese woman who was an HTLV-1 carrier had angioimmunoblastic lymphadenopathy with dysproteinemia (AILD)-like dysplasia that transformed into AILD-type lymphoma after 3 years. Complete remission was achieved with interferon-alpha (IFN-alpha) treatment following a previous combination of anticancer drug
Pyomyositis.: Am Fam Physician. 1996 Aug;54(2):565-9. Unique Identifier : AIDSLINE MED/96320130; Dunkerley GR; Older J; Onwochei B; Pazienza J; St. Clare's Hospital, Schenectady, New York, USA.; In the past, most cases of pyomyositis occurred among persons living in tropical climates, with the most common pathogen being Staphylococcus aureus. Increased numbers of cases have been reported more recently in North America, particularly in immunocompromised persons, such as those infected with the human immunodefi
Antiretroviral drug treatment for HIV/AIDS.: Am Fam Physician. 1996 Aug;54(2):574-80, 587-8. Unique Identifier : AIDSLINE MED/96320131; Goldschmidt RH; Moy A; San Francisco General Hospital, California, USA.; As new antiretroviral drugs for the treatment of human immunodeficiency virus (HIV) infection and new tests to measure HIV infection have become available, primary care clinicians now have more management options than ever before. Viral load measurements are becoming more accepted as a means of assessing HIV disease a
CD20 (pan-B cell antigen) expression on bone marrow-derived T cells.: Am J Clin Pathol. 1996 Jul;106(1):78-81. Unique Identifier : AIDSLINE MED/96291101; Algino KM; Thomason RW; King DE; Montiel MM; Craig FE; Department of Pathology, University of Texas Health Science; Center, San Antonio 78284, USA.; Antibodies directed against CD20 (L26, Leu 16, and B1) are frequently used to determine the presence of B lymphocytes. However, recent publications describe the unexpected presence of CD20-positive T cells in the peripheral blood of normal subjects and occasional T-cell neoplasms that express CD20. To determine the pr
Acquired factor V inhibitor in a patient with acquired human immunodeficiency syndrome [letter]: Am J Hematol. 1996 Aug;52(4):332-3. Unique Identifier : AIDSLINE MED/96319653; Brickner LA; Scannell KA; Sahud MA
Fas antigen expression and its relationship with apoptosis in human hepatocellular carcinoma and noncancerous tissues.: Am J Pathol. 1996 Aug;149(2):429-37. Unique Identifier : AIDSLINE MED/96312846; Higaki K; Yano H; Kojiro M; First Department of Pathology, Kurume University School of; Medicine, Japan.; Apoptosis, a programmed cell death, can be observed in the tissues of viral or autoimmune hepatitis and of hepatocellular carcinoma. Fas antigen (Fas) was proposed as a protein that triggers apoptosis. To elucidate the relationship between Fas expression and its location in hepatocellular carcinoma cells, we histochem
T cell subsets in normal human epidermis.: Am J Pathol. 1996 Aug;149(2):665-74. Unique Identifier : AIDSLINE MED/96312868; Spetz AL; Strominger J; Groh-Spies V; Division of Tumor Virology, Dana Farber Cancer Institute, Boston,; Massachusetts, USA.; Freshly isolated human lymphocytes from normal epidermis were characterized with respect to distribution of subsets. The major T cell receptor-alpha beta + compartment was enriched for CD4+, for CD8 alpha alpha +, and for CD4-CD8-T lymphocytes compared with peripheral blood lymphocytes. Furthermore, the majority of ep
Preventing opportunistic infections in human immunodeficiency virus-infected persons: implications for the developing world.: Am J Trop Med Hyg. 1996 Jul;55(1):1-11. Unique Identifier : AIDSLINE MED/96320181; Kaplan JE; Hu DJ; Holmes KK; Jaffe HW; Masur H; De Cock KM; Division of AIDS, STD, and TB Laboratory Research, National; Center for Infectious Diseases, Centers for Disease Control and; Prevention, Atlanta, Georgia, USA.; More than 18 million persons in the world are estimated to have been infected with human immunodeficiency virus (HIV), the cause of the acquired immunodeficiency syndrome (AIDS). As immunodeficiency progresses, these persons become susceptible to a wide variety of opportunistic infections (OIs) The spectrum of OIs var
Comparability of treatment groups and risk factors for parasitemia at the first antenatal clinic visit in a study of malaria treatment and prevention in pregnancy in rural Malawi.: Am J Trop Med Hyg. 1996;55(1 Suppl):17-23. Unique Identifier : AIDSLINE MED/96320168; Steketee RW; Wirima JJ; Slutsker L; Breman JG; Heymann DL; Division of Parasitic Diseases, National Center for Infectious; Diseases, Centers for Disease Control and Prevention, Atlanta,; Georgia, USA.; The problems of Plasmodium falciparum infection in pregnant women have been described in numerous sub-Saharan African countries, but the frequency of parasitemia at the first antenatal visit and risk factors for infection have not been fully investigated. During a prospective antimalarial treatment and prophylaxis tri
Malaria parasite infection during pregnancy and at delivery in mother, placenta, and newborn: efficacy of chloroquine and mefloquine in rural Malawi.: Am J Trop Med Hyg. 1996;55(1 Suppl):24-32. Unique Identifier : AIDSLINE MED/96320169; Steketee RW; Wirima JJ; Slutsker L; Roberts JM; Khoromana CO; Heymann DL; Breman JG; Division of Parasitic Diseases, National Center for Infectious; Diseases, Centers for Disease Control and Prevention, Atlanta,; Georgia, USA.; Despite international recommendations to use malaria treatment and prevention in pregnant women in malaria-endemic areas, few studies have evaluated the efficacy of available antimalarial regimens. This issue is of particular concern in the face of spreading chloroquine (CQ)-resistance of Plasmodium falciparum in mala
The effect of malaria and malaria prevention in pregnancy on offspring birthweight, prematurity, and intrauterine growth retardation in rural Malawi.: Am J Trop Med Hyg. 1996;55(1 Suppl):33-41. Unique Identifier : AIDSLINE MED/96320170; Steketee RW; Wirima JJ; Hightower AW; Slutsker L; Heymann DL; Breman JG; Division of Parasitic Diseases, National Center for Infectious; Diseases, Centers for Disease Control and Prevention, Atlanta,; Georgia, USA.; While there is broad evidence for the adverse effects of Plasmodium falciparum infection in pregnancy, and the World Health Organization recommends preventive strategies, there is markedly reduced efficacy in sub-Saharan Africa of the most widely available, affordable and used antimala
Impairment of a pregnant woman's acquired ability to limit Plasmodium falciparum by infection with human immunodeficiency virus type-1.: Am J Trop Med Hyg. 1996;55(1 Suppl):42-9. Unique Identifier : AIDSLINE MED/96320171; Steketee RW; Wirima JJ; Bloland PB; Chilima B; Mermin JH; Chitsulo L; Breman JG; Division of Parasitic Diseases, National Center for Infectious; Diseases, Centers for Disease Control and Prevention, Atlanta,; Georgia, USA.; In Africa, the human immunodeficiency virus (HIV) is the most serious emerging infection and Plasmodium falciparum malaria is one of the most prevalent infectious diseases. Both infections have serious consequences in pregnant women, their fetuses, and infants. We examined the association between HIV and P. falciparum
Malaria treatment and prevention in pregnancy: indications for use and adverse events associated with use of chloroquine or mefloquine.: Am J Trop Med Hyg. 1996;55(1 Suppl):50-6. Unique Identifier : AIDSLINE MED/96320172; Steketee RW; Wirima JJ; Slutsker L; Khoromana CO; Heymann DL; Breman JG; Division of Parasitic Diseases, National Center for Infectious; Diseases, Centers for Disease Control and Prevention, Atlanta,; Georgia, USA.; In sub-Saharan Africa, women frequently report a variety of symptoms during pregnancy, some of which indicate possible illness. Given the adverse impact of malaria in pregnancy, these events may be important for at least two reasons: it may be possible to use reported fever illness as a determinant of which women need
Prospective assessment of mortality among a cohort of pregnant women in rural Malawi.: Am J Trop Med Hyg. 1996;55(1 Suppl):66-70. Unique Identifier : AIDSLINE MED/96320175; McDermott JM; Slutsker L; Steketee RW; Wirima JJ; Breman JG; Heymann DL; Division of Parasitic Diseases, National Center for Infectious; Diseases, Centers for Disease Control and Prevention, Atlanta,; Georgia, USA.; Maternal mortality has recently received attention as a neglected public health problem in many developing countries where mortality rates are estimated to be 8-200 times those in developed countries. Most maternal mortality estimates in sub-Saharan Africa have used retrospective methods because of the lack of large p
Objectives and methodology in a study of malaria treatment and prevention in pregnancy in rural Malawi: The Mangochi Malaria Research Project.: Am J Trop Med Hyg. 1996;55(1 Suppl):8-16. Unique Identifier : AIDSLINE MED/96320167; Steketee RW; Wirima JJ; Slutsker WL; Khoromana CO; Breman JG; Heymann DL; Division of Parasitic Diseases, National Center for Infectious; Diseases, Centers for Disease Control and Prevention, Atlanta,; Georgia, USA.; Malaria infection due to Plasmodium falciparum has been widely recognized as associated with important adverse consequences in pregnant women, particularly in areas of high transmission. Although strategies using antimalarial drugs for prevention had been recommended, even by the late 1980s, few studies had been carri
Rates and risk factors for mortality during the first two years of life in rural Malawi.: Am J Trop Med Hyg. 1996;55(1 Suppl):82-6. Unique Identifier : AIDSLINE MED/96320178; Bloland P; Slutsker L; Steketee RW; Wirima JJ; Heymann DL; Breman JG; Division of Parasitic Diseases, National Center for Infectious; Diseases, Centers for Disease Control and Prevention, Atlanta,; Georgia, USA.; Developing nations in sub-Saharan Africa experience childhood mortality rates that are much higher than any other region of the world. In a rural Malawian community we investigated risk factors for deaths occurring during the neonatal (birth-28 days), postneonatal (29-365 days), infant (birth-365 days), and second-yea
Developing effective strategies for malaria prevention programs for pregnant African women.: Am J Trop Med Hyg. 1996;55(1 Suppl):95-100. Unique Identifier : AIDSLINE MED/96320180; Steketee RW; Wirima JJ; Campbell CC; Division of HIV/AIDS, National Center for Prevention Services,; Centers for Disease Control and Prevention, Atlanta, Georgia,; USA.; The control of malaria in pregnant African women, one of several child survival strategies applied through antenatal care, has been particularly challenging. Prevention and control recommendations for typical areas of high Plasmodium falciparum transmission have promoted the use of antimalarial chemoprophylaxis to pre
Nurses combat HIV/AIDS in adolescent community.: Am Nurse. 1995 Nov-Dec;27(8):16. Unique Identifier : AIDSLINE MED/96322625; Campbell K
Home care nursing: bringing the hospital home.: Am Nurse. 1995 Nov-Dec;27(8):17. Unique Identifier : AIDSLINE MED/96322626; Lemkin P
Immunohistochemical characterisation of immunological changes at the tumour site after chemo-immunotherapy with doxorubicin, interleukin-2 and interferon-gamma.: Anticancer Res. 1996 May-Jun;16(3A):1145-54. Unique Identifier : AIDSLINE MED/96273137; Lumsden AJ; Codde JP; Van der Meide PH; Gray BN; Centre for Applied Cancer Studies, Royal Perth Hospital,; Australia.; Chemo-immunotherapy for the treatment of cancer, whilst promising from a preclinical and clinical perspective, remains limited by a lack of clear understanding of the in vivo antitumour mechanisms of this multi modality strategy. There is now strong evidence that systemic immunological parameters do not correlate with
Human T lymphotropic virus type I in arthropathy and autoimmune disorders.: Arthritis Rheum. 1996 Aug;39(8):1410-8. Unique Identifier : AIDSLINE MED/96320246; Nishioka K; Sumida T; Hasunuma T; Institute of Medical Science, St. Marianna University School of; Medicine, Kawasaki, Japan.; The progressive nature of the disease and the persistent inflammation affecting various organs are common features of idiopathic autoimmune disorders of unknown etiology. Therefore, the HTLV-I-associated disorders described in the present review are outstandingly important models for our understanding of the pathologi
The relationship between rheumatoid arthritis and the acquired immunodeficiency syndrome: comment on the article by Ornstein et al [letter]: Arthritis Rheum. 1996 Aug;39(8):1437-9. Unique Identifier : AIDSLINE MED/96320255; Adebajo AO; Hazleman BL
Organ transplantation and the inevitable debate as to what constitutes a basic health care benefit.: Terasaki, Paul; Cecka, J.M., eds. Clinical Transplants 1993. Los Angeles, CA: UCLA Tissue Typing Laboratory, 1994 :359-391. Unique Identifier : AIDSLINE KIE/50102; Evans RW
When doctors and patients decide to test the far limits of treatment. [News].: New York Times. 1995 Dec 19;:C3. Unique Identifier : AIDSLINE KIE/50255; Altman LK
Surgery gives man new best friends. [News].: New York Times. 1995 Dec 17;:E3. Unique Identifier : AIDSLINE KIE/50256; Stryker J
Cross-species transplants raise concerns about human safety. [News].: New York Times. 1996 Jan 9;:11, 17. Unique Identifier : AIDSLINE KIE/50257; Altman L